cimetidine has been researched along with lidocaine in 67 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (44.78) | 18.7374 |
1990's | 6 (8.96) | 18.2507 |
2000's | 18 (26.87) | 29.6817 |
2010's | 13 (19.40) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Artursson, P; Mateus, A; Matsson, P | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Grönneberg, R; Hägermark, O; Strandberg, K | 1 |
Alzamora, F; Cunha-Melo, JR; Freire-Maia, L; Gonzaga, HM | 1 |
Daifotis, Z; Danou, K; Kaniaris, P; Karayannacos, P; Sabatakaki, A | 1 |
Kishikawa, K; Miyashita, K; Namiki, A; Saitoh, K | 1 |
Bar-Meir, S; Bruck, R; Krepel, Z | 1 |
Collier, PS; Flynn, RJ; Howard, PJ; Moore, J | 2 |
Bianchine, JR; Gerber, MC; Gerber, N; Tejwani, GA | 1 |
Heath, CA; Johnson, RF; Roberts, RK; Schenker, S; Speeg, KV | 1 |
Kapil, RP; Lalonde, RL; Mattern, AL; North, DS | 1 |
Cheek, DB; Dailey, PA; Healy, K; Hughes, SC; Rosen, MA; Shnider, SM | 1 |
Itho, H; Kawamata, Y; Koyama, C; Nishigaki, R; Shibasaki, S; Ueno, F; Umemura, K | 1 |
Curry, SH; Gotz, VP; Lopez, LM; Mehta, JL; Parish, RC | 1 |
Kim, KC; Tasch, MD | 1 |
Cross, R; Foster, J; Patterson, JH; Powell, JR; Wargin, W | 1 |
Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR | 1 |
Bentley, JB; Fukui, T; Gandolfi, AJ; Glass, SJ; Jackson, JE; Plachetka, JR | 1 |
Abernethy, DR; Schwartz, JB; Todd, EL | 1 |
Wood, JR | 1 |
Greene, WL; Levinson, MJ; Self, TH | 1 |
Sedman, AJ | 1 |
Greene, W | 1 |
Feely, J | 1 |
Bauer, LA; Blouin, RA; Edwards, WA; Randolph, FP | 1 |
Frank, WO; Humphries, TJ; Myerson, RM; Peace, KE; Seaman, JJ | 1 |
Birkett, DJ; Foenander, T; Lillywhite, K; Miners, JO; Wanwimolruk, S; Wing, LM | 1 |
Karmen, A; Keren, G; Knapp, AB; Levitt, B; Maguire, W; Miura, DS; Somberg, JC | 1 |
D'Arcy, PF | 1 |
Powell, JR | 1 |
DiGregorio, GJ; Fruncillo, RJ; Soll, A | 1 |
Feely, J; McAllister, CB; Wilkinson, GR; Wood, AJ | 1 |
Loi, CM; Schmucker, DL; Vestal, RE; Wei, X | 1 |
Borzone, S; Caglieris, S; Ghia, M; Giannini, E; Mattioli, F; Mereto, E; Risso, D; Testa, R | 1 |
Chichester, C; McKindley, DS; Raymond, R | 1 |
Hashiguchi, M; Kasanuki, H; Rikihisa, T; Shiga, T; Urae, A | 1 |
Arase, S; Miyaoka, Y; Skrebova, N; Takiwaki, H | 1 |
Honda, K; Inomata, S; Misawa, S; Nagashima, A; Tanaka, E | 1 |
Honda, K; Inomata, S; Nakamura, T; Tanaka, E | 1 |
Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI; Usui, T | 1 |
5 review(s) available for cimetidine and lidocaine
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interactions with cimetidine: an update.
Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Aspirin; Aziridines; Benzodiazepines; Benzoquinones; Cimetidine; Drug Interactions; Humans; Ibuprofen; Imipramine; Kinetics; Lidocaine; Liver Circulation; Pituitary Gland; Procaine; Xanthines | 1985 |
Cimetidine-drug interactions.
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Chlormethiazole; Cimetidine; Drug Interactions; Humans; Ketoconazole; Kidney; Lidocaine; Morphine; Penicillins; Theophylline | 1984 |
Drug interactions involving cimetidine--mechanisms, documentation, implications.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antacids; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifungal Agents; Aspirin; Benzodiazepines; Cimetidine; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Iron; Lidocaine; Pancreas; Phenytoin; Prednisolone; Theophylline; Vitamin B 12 | 1984 |
Interaction of cimetidine with other drugs.
Topics: Aged; Chlormethiazole; Cimetidine; Diazepam; Drug Interactions; Guanidines; Humans; Lidocaine; Liver; Liver Circulation; Phenytoin; Propranolol; Tissue Distribution; Warfarin | 1983 |
9 trial(s) available for cimetidine and lidocaine
Article | Year |
---|---|
[Famotidine does not modify the plasma levels of lidocaine for spinal anesthesia. A comparative study of famotidine and cimetidine].
Topics: Aged; Anesthesia, Spinal; Cimetidine; Depression, Chemical; Famotidine; Gastric Acid; Humans; Lidocaine; Male | 1992 |
Effects of famotidine and cimetidine on plasma levels of epidurally administered lignocaine.
Topics: Anesthesia, Epidural; Cimetidine; Famotidine; Female; Humans; Lidocaine; Male; Middle Aged; Pneumonia, Aspiration; Preanesthetic Medication; Time Factors | 1990 |
Single dose oral H2-antagonists do not affect plasma lidocaine levels in the parturient.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Cimetidine; Drug Interactions; Female; Fetal Blood; Humans; Lidocaine; Pregnancy; Randomized Controlled Trials as Topic; Ranitidine | 1989 |
Effect of intravenous cimetidine on lignocaine disposition during extradural caesarean section.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Cimetidine; Female; Humans; Injections, Intravenous; Lidocaine; Pregnancy; Random Allocation | 1989 |
The effect of histamine-2 receptor antagonists on tocainide pharmacokinetics.
Topics: Adult; Anti-Arrhythmia Agents; Cimetidine; Drug Interactions; Female; Half-Life; Histamine H2 Antagonists; Humans; Lidocaine; Male; Middle Aged; Ranitidine; Tocainide | 1988 |
Effect of duration of lidocaine infusion and route of cimetidine administration on lidocaine pharmacokinetics.
Topics: Adult; Cimetidine; Dealkylation; Drug Interactions; Humans; Infusions, Intravenous; Kinetics; Lidocaine; Male | 1986 |
Effects of histamine-2 receptor blockade on lidocaine kinetics.
Topics: Administration, Oral; Adult; Analysis of Variance; Chromatography, High Pressure Liquid; Cimetidine; Double-Blind Method; Drug Interactions; Half-Life; Humans; Infusions, Parenteral; Kinetics; Lidocaine; Male; Orosomucoid; Ranitidine | 1985 |
Increased toxicity and reduced clearance of lidocaine by cimetidine.
Topics: Adult; Blood Proteins; Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine; Male; Metabolic Clearance Rate; Protein Binding | 1982 |
Effect of cimetidine and probenecid on pilsicainide renal clearance in humans.
Topics: Adult; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Cimetidine; Cross-Over Studies; Enzyme Inhibitors; Humans; Kidney; Lidocaine; Male; Probenecid; Reference Values; Uricosuric Agents | 2000 |
53 other study(ies) available for cimetidine and lidocaine
Article | Year |
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[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of histamine receptor antagonists on histamine-induced responses in human skin.
Topics: Adult; Axons; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Injections, Intradermal; Lidocaine; Metiamide; Pyrilamine; Reflex; Skin | 1979 |
Gastric secretion induced by scorpion toxin.
Topics: Animals; Anura; Atropine; Cimetidine; Gastric Juice; Lidocaine; Rats; Scorpion Venoms; Stimulation, Chemical; Vagotomy | 1979 |
Cimetidine and omeprazole have different effects on hepatic extraction of lidocaine in rats.
Topics: Animals; Cimetidine; Indocyanine Green; Lidocaine; Liver; Male; Omeprazole; Rats; Rats, Inbred Strains | 1990 |
Effect of H2-receptor antagonists on steady-state extraction of indocyanine green and lidocaine by the perfused rat liver.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Indocyanine Green; Lidocaine; Liver; Male; Oxygen Consumption; Perfusion; Ranitidine; Rats; Rats, Inbred Strains | 1986 |
Effect of cimetidine and ranitidine on lidocaine concentrations during epidural anesthesia for cesarean section.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Cimetidine; Female; Fetal Blood; Humans; Lidocaine; Pregnancy; Ranitidine | 1988 |
Effects of cimetidine on lidocaine distribution in rats.
Topics: Animals; Blood Proteins; Cimetidine; Drug Interactions; Erythrocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Male; Mathematics; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Serum lidocaine concentrations following application to the oropharynx: effects of cimetidine.
Topics: Administration, Topical; Adult; Cimetidine; Drug Interactions; Humans; Lidocaine; Oropharynx; Orosomucoid | 1987 |
Effects of cimetidine and ranitidine on local anesthetic central nervous system toxicity in mice.
Topics: Anesthetics, Local; Animals; Brain Diseases; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Lidocaine; Mice; Procaine; Ranitidine; Seizures | 1986 |
The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction.
Topics: Administration, Oral; Aged; Cimetidine; Drug Interactions; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Ventricular Fibrillation | 1987 |
Lack of interaction between verapamil and cimetidine.
Topics: Administration, Oral; Adult; Biological Availability; Blood Proteins; Chromatography, Gas; Cimetidine; Drug Administration Schedule; Drug Interactions; Electrocardiography; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Lidocaine; Male; Random Allocation; Verapamil | 1985 |
H2 receptor antagonists: cimetidine and ranitidine.
Topics: Cimetidine; Drug Interactions; Furans; Guanidines; Histamine H2 Antagonists; Humans; Lidocaine; Propranolol; Ranitidine | 1983 |
Cimetidine drug interactions.
Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Anti-Arrhythmia Agents; Anticonvulsants; Benzodiazepines; Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine; Peptic Ulcer; Warfarin | 1983 |
Cimetidine-induced decrease in lidocaine metabolism.
Topics: Adult; Cimetidine; Drug Interactions; Humans; Kinetics; Lidocaine; Liver; Liver Circulation; Male | 1984 |
Lidocaine-cimetidine interaction.
Topics: Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine; Research Design | 1983 |
Lidocaine disposition--sex differences and effects of cimetidine.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Biological Availability; Blood Proteins; Cimetidine; Drug Interactions; Female; Humans; Injections, Intravenous; Lidocaine; Male; Protein Binding; Sex Factors; Smoking | 1984 |
The cimetidine-lidocaine interaction.
Topics: Cimetidine; Diphenhydramine; Drug Interactions; Female; Guanidines; Humans; Lidocaine; Male; Middle Aged | 1983 |
Early reports on drug interactions.
Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine | 1983 |
Cimetidine and lidocaine.
Topics: Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine | 1983 |
Effect of cimetidine on the pharmacokinetics of quinidine and lidocaine in the rat.
Topics: Animals; Cimetidine; Drug Interactions; Guanidines; Kinetics; Lidocaine; Male; Quinidine; Rats; Rats, Inbred Strains | 1983 |
Lidocaine-cimetidine interaction can be toxic.
Topics: Arrhythmias, Cardiac; Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine; Peptic Ulcer | 1982 |
Characterization of the independent and combined effects of two inhibitors on oxidative drug metabolism in rat liver microsomes.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cimetidine; Kinetics; Lidocaine; Male; Mexiletine; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1995 |
Effects of reduced glutathione and n-acetylcysteine on lidocaine metabolism in cimetidine treated rats.
Topics: Acetylcysteine; Anesthetics, Local; Animals; Cimetidine; Drug Interactions; Fluorescence Polarization Immunoassay; Free Radical Scavengers; Glutathione; Histamine H2 Antagonists; Injections, Intraperitoneal; Lidocaine; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Effect of endotoxin shock on the clearance of lidocaine and indocyanine green in the perfused rat liver.
Topics: Anesthetics, Local; Animals; Cimetidine; Coloring Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endotoxins; Enzyme Inhibitors; Indocyanine Green; Isoenzymes; Lidocaine; Liver; Male; Metabolic Clearance Rate; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Shock, Septic | 1999 |
Localized heat urticaria: a clinical study using laser Doppler flowmetry.
Topics: Administration, Topical; Aged; Cimetidine; Diphenhydramine; Female; Histamine; Histamine H1 Antagonists; Hot Temperature; Humans; Laser-Doppler Flowmetry; Lidocaine; Male; Middle Aged; Phenothiazines; Skin; Time Factors; Urticaria | 2001 |
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
Topics: Animals; Cimetidine; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ketoconazole; Lidocaine; Microsomes, Liver; Midazolam; Neuromuscular Depolarizing Agents; Pentobarbital; Pharmacogenetics; Premedication; Rats; Theophylline; Thiamylal | 2005 |
Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.
Topics: Amides; Anesthetics, Local; Bupivacaine; Cells, Cultured; Cimetidine; Clonidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Lidocaine; Microsomes, Liver; Midazolam; Premedication; Ropivacaine; Thiamylal; Vecuronium Bromide | 2006 |
Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Benzamides; Cations; Cell Line; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Isoquinolines; Lidocaine; Metformin; Organic Cation Transport Proteins; Procainamide; Quinidine; Rats | 2008 |