cimetidine and isoniazid

cimetidine has been researched along with isoniazid in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (25.71)	18.7374
1990's	5 (14.29)	18.2507
2000's	9 (25.71)	29.6817
2010's	12 (34.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Dansette, PM; Fontana, E; Poli, SM	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Areas, V; Bermejo, T; de Juana, P; García, B; Jiménez, I; Obeso, G; Zaborras, E	1
Jensen, LS; Rowland, GN; Wyatt, CL	1
Cai, YA; Lindros, KO; Penttilä, KE	1
Bhavsar, VH; Mistry, SD; Vaccharajani, MV	1
Gredeby, H; Höglund, P; Nilsson, LG; Paulsen, O	1
Baciewicz, AM	1
Bhavsar, VH; Joshi, NJ; Kelkar, VV; Patel, SR	1
Greenblatt, DJ; Grehl, H; Harmatz, JS; Ochs, HR; Verburg-Ochs, B	1
Abernethy, DR; Greenblatt, DJ; Ochs, HR; Shader, RI	1
Bilynskiĭ, BT; Shparik, IaV	1
Bengoa, JM; Bolt, MJ; Rosenberg, IH	1
Kern, F; Mallory, A	1
Capron, MH; Lauga, J	1
Agarwal, S; Gupta, U; Kalra, BS; Khurana, N; Tayal, V	1
Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH	1

Reviews

5 review(s) available for cimetidine and isoniazid

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Carbamazepine drug interactions. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin	1986
[Carcinogenicity of various drugs]. Voprosy onkologii, 1984, Volume: 30, Issue:8 Topics: Adult; Animals; Anti-Bacterial Agents; Arsenicals; Barbiturates; Brain Neoplasms; Carcinogens; Child; Cimetidine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Isoniazid; Kidney Neoplasms; Male; Mice; Phenacetin; Pregnancy; Prenatal Exposure Delayed Effects; Risk; Secologanin Tryptamine Alkaloids	1984
Drug-induced pancreatitis: a critical review. Gastroenterology, 1980, Volume: 78, Issue:4 Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Cholestyramine Resin; Cimetidine; Cyproheptadine; Dextropropoxyphene; Diazoxide; Diuretics; Estrogens; Ethacrynic Acid; Furosemide; Histamine; Humans; Hypercalcemia; Indomethacin; Isoniazid; Mercaptopurine; Narcotics; Pancreatitis; Phenformin; Procainamide; Rifampin; Salicylates; Sodium Chloride Symporter Inhibitors; Sulfonamides; Tetracycline	1980

Other Studies

30 other study(ies) available for cimetidine and isoniazid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Interaction between isoniazid and carbamazepine potentiated by cimetidine. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6 Topics: Aged; Carbamazepine; Cimetidine; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Isoniazid; Male; Risk Factors	1992
Effect of feeding isoniazid and cimetidine on growth and bone development in male broiler chicks. Poultry science, 1990, Volume: 69, Issue:8 Topics: Animals; Bone Development; Bone Diseases; Calcium; Chickens; Cholecalciferol; Cimetidine; Isoniazid; Male; Tensile Strength; Tibia; Time Factors; Weight Gain	1990
Role of ethanol-inducible cytochrome P-450 IIE1 in carbon tetrachloride-induced damage to centrilobular hepatocytes from ethanol-treated rats. Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:5 Topics: Animals; Carbon Tetrachloride; Cell Separation; Cell Survival; Cells, Cultured; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanol; Isoniazid; Liver; Male; Rats	1990
A study of the effect of isoniazid and cimetidine on dark adaptation of human eye. Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:1 Topics: Adult; Cimetidine; Dark Adaptation; Eye; Humans; Isoniazid; Male; Ocular Physiological Phenomena; Photoreceptor Cells	1990
No interaction between H2 blockers and isoniazid. European journal of respiratory diseases, 1986, Volume: 68, Issue:4 Topics: Absorption; Acetylation; Adult; Chromatography, High Pressure Liquid; Cimetidine; Drug Interactions; Female; Half-Life; Histamine H2 Antagonists; Humans; Isoniazid; Kinetics; Male; Middle Aged; Ranitidine; Spectrophotometry; Time Factors	1986
The effect of isoniazid and cimetidine on ethanol and methanol elimination in rabbits. Acta pharmacologica et toxicologica, 1986, Volume: 58, Issue:3 Topics: Animals; Cimetidine; Ethanol; Female; Isoniazid; Male; Metabolic Clearance Rate; Methanol; Rabbits	1986
Cimetidine inhibits the hepatic hydroxylation of vitamin D. Nutrition reviews, 1985, Volume: 43, Issue:6 Topics: Adolescent; Animals; Child; Cholestanetriol 26-Monooxygenase; Cimetidine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isoniazid; Liver; Male; Rats; Steroid Hydroxylases; Vitamin D	1985
Disposition of clotiazepam: influence of age, sex, oral contraceptives, cimetidine, isoniazid and ethanol. European journal of clinical pharmacology, 1984, Volume: 26, Issue:1 Topics: Adult; Aged; Aging; Azepines; Cimetidine; Contraceptives, Oral, Hormonal; Drug Interactions; Ethanol; Female; Half-Life; Humans; Isoniazid; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Sex Factors	1984
Benzodiazepine drug-drug interactions commonly occurring in clinical practice. Current medical research and opinion, 1984, Volume: 8 Suppl 4 Topics: Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Contraceptives, Oral; Disulfiram; Drug Interactions; Enzyme Induction; Ethanol; Humans; Isoniazid; Kinetics; Liver; Mixed Function Oxygenases; Propranolol	1984
Hepatic vitamin D 25-hydroxylase inhibition by cimetidine and isoniazid. The Journal of laboratory and clinical medicine, 1984, Volume: 104, Issue:4 Topics: Animals; Cholestanetriol 26-Monooxygenase; Cimetidine; Isoniazid; Liver; Male; Rats; Rats, Inbred Strains; Steroid Hydroxylases	1984
[Breast cancer in the male]. Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36 Topics: Breast Neoplasms; Cimetidine; Digitalis Glycosides; Humans; Isoniazid; Male; Risk Factors; Sex Factors; Spironolactone	1993
Hepatoprotective effect of tocopherol against isoniazid and rifampicin induced hepatotoxicity in albino rabbits. Indian journal of experimental biology, 2007, Volume: 45, Issue:12 Topics: Animals; Antioxidants; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cimetidine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Isoniazid; Liver Diseases; Rabbits; Rifampin; Tocopherols	2007
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism. The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:1 Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System; Diuretics; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Furosemide; Half-Life; Infusions, Intravenous; Injections, Intravenous; Isoniazid; Male; Methylcholanthrene; Orphenadrine; Proadifen; Quinine; Rats; Rats, Sprague-Dawley; Troleandomycin; Weight Gain	2009