cimetidine and ibuprofen

cimetidine has been researched along with ibuprofen in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (33.87)	18.7374
1990's	6 (9.68)	18.2507
2000's	16 (25.81)	29.6817
2010's	17 (27.42)	24.3611
2020's	2 (3.23)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T	1
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T	1
Chang, TK; Ensom, MH; Kiang, TK	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Blocher, CR; Byrne, K; Carey, PD; Michna, B; Sielaff, TD; Sugerman, HJ; Vasquez, A	1
Blocher, CR; Byrne, K; Carey, PD; Hirsh, JI; Sielaff, TD; Sugerman, HJ; Tatum, JL; Vasquez, A	1
Madhavan, S; Schondelmeyer, SW	1
Small, RE; Wood, JH	1
Evans, AM; Nation, RL; Sansom, LN	1
Bianchine, JR; Gerber, MC; Gerber, N; Tejwani, GA	1
Forsyth, DR; Jayasinghe, KS; Roberts, CJ	1
Bartle, EJ; Bender, EM; Carter, WH; Hansbrough, JF; Mansour, MA; Zapata-Sirvent, RL	1
Bartle, EJ; Hansbrough, JF; Zapata-Sirvent, R	1
Carter, WH; Hansbrough, JF; Hoyt, D; Shackford, SR; Zapata-Sirvent, RL	1
Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL	1
Hatakeyama, H; Hirose, K; Jyoyama, H; Matsubara, T; Otsubo, S; Touchi, A	1
Johnson, SM; Karnes, HT; Rajasekharaiah, K; Small, RE; Stephenson, DW; Willis, HE; Wood, JH	1
Bender, EM; Hansbrough, JF; Zapata-Sirvent, RL	1
Blocher, CR; Kellum, JM; Sielaff, TD; Sugerman, HJ; Tatum, JL	1
Greenblatt, DJ; Matlis, R; Ochs, HR; Weinbrenner, J	1
Claman, HN; Hansbrough, J; Peterson, V; Zapata-Sirvent, R	1
Bliss, M; Conrad, KA; Mayersohn, M	1
Christensen, JM; Parrott, KA	1
Flemström, G; Garner, A; Heylings, JR; Rees, WD	1
Carey, PD; Fowler, AA; Sugerman, HJ; Walsh, CJ; Windsor, AC	1
Fisher, BJ; Fowler, AA; Leeper-Woodford, SK; Sugerman, HJ	1
Byrne, K; Carey, D; Fisher, B; Fowler, AA; Leeper-Woodford, SK; Sugerman, HJ; Walsh, C	1
Jennis, T; Lu, HC; Marcus, S; Ruck, B; Shih, RD	1
Bytautiene, E; Garfield, RE; Maul, H; Saade, GR; Vedernikov, Y	1
SHUGAR, D; SZER, W	1
BLAUG, SM; RICH, AG	1
BANKER, GS; WOLFSON, BB	1
Bytautiene, E; Garfield, RE; Romero, R; Saade, GR; Vedernikov, YP	1
Gonnissen, Y; Peeters, E; Remon, JP; Verhoeven, E; Vervaet, C	1
Jung, JA; Parvez, MM; Shin, HJ; Shin, JG	1
Baek, JS; Lee, YH; Loo, SCJ; Tan, NS; Yeo, EW	1
Hassan, ZM; Jafarzadeh, A; Khorramdelazad, H; Masoumi, J; Nemati, M; Oladpour, O; Rezayati, MT; Taghipour, F; Taghipour, Z	1
Hassan, ZM; Jafarzadeh, A; Nemati, M; Oladpour, O; Rezayati, MT; Taghipour, F; Taghipour, Z	1

Reviews

3 review(s) available for cimetidine and ibuprofen

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug interactions with cimetidine: an update. Pharmacology & therapeutics, 1985, Volume: 27, Issue:3 Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Aspirin; Aziridines; Benzodiazepines; Benzoquinones; Cimetidine; Drug Interactions; Humans; Ibuprofen; Imipramine; Kinetics; Lidocaine; Liver Circulation; Pituitary Gland; Procaine; Xanthines	1985

Trials

2 trial(s) available for cimetidine and ibuprofen

Article	Year
Lack of effect of cimetidine on the pharmacokinetics of R(-)- and S(+)-ibuprofen. British journal of clinical pharmacology, 1989, Volume: 28, Issue:2 Topics: Absorption; Adult; Biotransformation; Blood Proteins; Cimetidine; Drug Interactions; Humans; Ibuprofen; Male; Protein Binding; Stereoisomerism	1989
Do nizatidine and cimetidine interact with ibuprofen? European journal of clinical pharmacology, 1988, Volume: 35, Issue:1 Topics: Adult; Cimetidine; Double-Blind Method; Drug Interactions; Half-Life; Histamine H2 Antagonists; Humans; Ibuprofen; Male; Nizatidine; Thiazoles	1988

Other Studies

57 other study(ies) available for cimetidine and ibuprofen

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis	2001
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:5 Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Increased survival time after delayed histamine and prostaglandin blockade in a porcine model of severe sepsis-induced lung injury. Critical care medicine, 1990, Volume: 18, Issue:3 Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Extravascular Lung Water; Hemodynamics; Histamine Antagonists; Ibuprofen; Prostaglandin Antagonists; Pseudomonas Infections; Respiratory Distress Syndrome; Shock, Septic; Swine	1990
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS. Circulatory shock, 1990, Volume: 30, Issue:2 Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomonas Infections; Ranitidine; Respiratory Distress Syndrome; Respiratory Function Tests; Shock, Septic; Swine	1990
Pharmacists' evaluations of the nonprescription availability of metaproterenol, cimetidine, ibuprofen, and nystatin. American journal of hospital pharmacy, 1989, Volume: 46, Issue:12 Topics: Attitude of Health Personnel; Cimetidine; Ibuprofen; Metaproterenol; Nonprescription Drugs; Nystatin; Pharmacists; Regression Analysis; United States; United States Food and Drug Administration	1989
Influence of racial differences on effects of ranitidine and cimetidine on ibuprofen pharmacokinetics. Clinical pharmacy, 1989, Volume: 8, Issue:7 Topics: Black People; Cimetidine; Female; Humans; Ibuprofen; Male; Ranitidine; White People	1989
Postburn immunosuppression in an animal model. IV. Improved resistance to septic challenge with immunomodulating drugs. Surgery, 1986, Volume: 99, Issue:1 Topics: Animals; Anti-Infective Agents, Local; Burns; Cerium; Cimetidine; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Hypersensitivity, Delayed; Ibuprofen; Immune Tolerance; Immunity, Cellular; Infection Control; Infections; Mice; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory	1986
Prevention of posttraumatic alterations in lymphocyte subpopulations in mice by immunomodulating drugs. Archives of surgery (Chicago, Ill. : 1960), 1986, Volume: 121, Issue:1 Topics: Animals; Cimetidine; Corticosterone; Cyclophosphamide; Female; Ibuprofen; Leukocyte Count; Lymphocytes; Mice; Mice, Inbred Strains; Spleen; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Wounds and Injuries	1986
Immunomodulating drugs increase resistance against sepsis in traumatized mice. The Journal of trauma, 1986, Volume: 26, Issue:7 Topics: Adjuvants, Immunologic; Animals; Cimetidine; Cyclophosphamide; Female; Ibuprofen; Immune Tolerance; Infections; Mice; Mice, Inbred Strains; T-Lymphocytes, Regulatory; Wounds and Injuries	1986
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model. Surgery, 1987, Volume: 102, Issue:2 Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin; Methylprednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Distress Syndrome; Swine	1987
[Effect of the nonsteroidal anti-inflammatory drug 480156-S on hepatic drug-metabolizing activity and pharmacological action of diazepam and pentobarbital in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:4 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Cytochrome P-450 Enzyme System; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Liver; Male; Oxygenases; Pentobarbital; Phenylpropionates; Rats; Rats, Inbred Strains	1988
Effect of ranitidine and cimetidine on ibuprofen pharmacokinetics. Clinical pharmacy, 1988, Volume: 7, Issue:4 Topics: Adult; Cimetidine; Female; Humans; Ibuprofen; Male; Random Allocation; Ranitidine	1988
Prevention of alterations in postoperative lymphocyte subpopulations by cimetidine and ibuprofen. American journal of surgery, 1986, Volume: 151, Issue:2 Topics: Adult; Aged; Antibodies, Monoclonal; B-Lymphocytes; Cimetidine; Humans; Ibuprofen; Immunity, Cellular; Leukocyte Count; Lymphocytes; Middle Aged; Postoperative Period; Premedication; T-Lymphocytes	1986
Treatment of porcine Pseudomonas ARDS with combination drug therapy. The Journal of trauma, 1987, Volume: 27, Issue:12 Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug Combinations; Drug Therapy, Combination; Extracellular Space; Ibuprofen; Ketanserin; Lung; Methylprednisolone; Pseudomonas Infections; Respiratory Distress Syndrome; Serotonin; Swine	1987
Interaction of ibuprofen with the H-2 receptor antagonists ranitidine and cimetidine. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:6 Topics: Adult; Analysis of Variance; Biological Availability; Chromatography, High Pressure Liquid; Cimetidine; Drug Interactions; Female; Humans; Ibuprofen; Kinetics; Male; Ranitidine	1985
Postburn immunosuppression in an animal model. II. Restoration of cell-mediated immunity by immunomodulating drugs. Surgery, 1984, Volume: 95, Issue:3 Topics: Animals; Burns; Chlorides; Cimetidine; Cyclophosphamide; Dinitrofluorobenzene; Drug Hypersensitivity; Female; Ibuprofen; Immune Tolerance; Immunity, Cellular; Indomethacin; Lithium; Lithium Chloride; Mice; Mice, Inbred Strains	1984
Cimetidine does not alter ibuprofen kinetics after a single dose. British journal of clinical pharmacology, 1984, Volume: 18, Issue:4 Topics: Adult; Cimetidine; Drug Interactions; Humans; Ibuprofen; Kinetics; Male	1984
Influence of cimetidine on the disposition of ibuprofen in the rat. Research communications in chemical pathology and pharmacology, 1984, Volume: 43, Issue:3 Topics: Animals; Cimetidine; Drug Interactions; Gastric Mucosa; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Male; Models, Biological; Proadifen; Rats; Rats, Inbred Strains; Tissue Distribution	1984
Effect of carbenoxolone on alkaline secretion by isolated amphibian gastric and duodenal mucosa. European journal of clinical investigation, 1981, Volume: 11, Issue:6 Topics: Animals; Bicarbonates; Biological Transport; Carbenoxolone; Cimetidine; Dinoprostone; Duodenum; Gastric Mucosa; Glycyrrhetinic Acid; Ibuprofen; Intestinal Mucosa; Necturus; Prostaglandins E; Rana catesbeiana; Rana temporaria; Taurocholic Acid	1981
Multi-agent therapy in the treatment of sepsis-induced microvascular injury. The British journal of surgery, 1994, Volume: 81, Issue:12 Topics: Animals; Cell Membrane Permeability; Cimetidine; Diphenhydramine; Hemodynamics; Hypochlorous Acid; Ibuprofen; Microcirculation; Neutrophils; Pulmonary Alveoli; Sepsis; Superoxides; Swine; Vascular Diseases	1994
Pharmacologic reduction in tumor necrosis factor activity of pulmonary alveolar macrophages. American journal of respiratory cell and molecular biology, 1993, Volume: 8, Issue:2 Topics: Animals; Cells, Cultured; Cimetidine; Cyclooxygenase Inhibitors; Diphenhydramine; Histamine; Histamine H2 Antagonists; Ibuprofen; Lipopolysaccharides; Macrophages, Alveolar; Mice; Swine; Tumor Necrosis Factor-alpha	1993
Histamine receptor antagonists, cyclooxygenase blockade, and tumor necrosis factor during acute septic insult. Shock (Augusta, Ga.), 1998, Volume: 9, Issue:2 Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Cimetidine; Cyclooxygenase Inhibitors; Diphenhydramine; Disease Models, Animal; Drug Therapy, Combination; Histamine Antagonists; Hypertension, Pulmonary; Ibuprofen; Pseudomonas Infections; Swine; Tumor Necrosis Factor-alpha	1998
Pseudomethemoglobinemia: a case report and review of sulfhemoglobinemia. Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:8 Topics: Acetaminophen; Adolescent; Cimetidine; Diagnosis, Differential; Female; Humans; Ibuprofen; Methemoglobinemia; Naproxen; Oximetry; Suicide, Attempted; Sulfhemoglobinemia	1998
Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products. American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:6 Topics: Animals; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Histamine; Ibuprofen; Mast Cells; Oligopeptides; p-Methoxy-N-methylphenethylamine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Thrombin; Uterine Contraction	2003
Preparation of poly-5-fluorouridylic acid and the properties of halogenated poly-uridylic acids and their complexes with poly-adenylic acid. Acta biochimica Polonica, 1963, Volume: 10 Topics: Adenine Nucleotides; Adenosine Monophosphate; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Uracil Nucleotides; Uridine Monophosphate	1963
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION. Journal of pharmaceutical sciences, 1965, Volume: 54 Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines	1965
SOLUBILIZATION AND EVALUATION OF POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE BARBITURATE SYSTEMS. Journal of pharmaceutical sciences, 1965, Volume: 54 Topics: Barbiturates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Oxazoles; Oxazolidinones; Phenobarbital; Povidone; Research; Solubility	1965
Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women. American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:5 Topics: Cell Degranulation; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Ibuprofen; Linoleic Acids; Longitudinal Studies; Mast Cells; Myometrium; p-Methoxy-N-methylphenethylamine; Pregnancy; Uterine Contraction	2004
Coprocessing via spray drying as a formulation platform to improve the compactability of various drugs. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:1 Topics: Acetaminophen; Carbohydrates; Chemistry, Pharmaceutical; Cimetidine; Desiccation; Dosage Forms; Drug Compounding; Ibuprofen; Microscopy, Electron, Scanning; Models, Statistical; Particle Size; Povidone; Powders; Solubility; Technology, Pharmaceutical; X-Ray Diffraction	2008
Evaluation of Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Aminosalicylic Acid; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cimetidine; Drug Interactions; HEK293 Cells; Humans; Ibuprofen; Liver-Specific Organic Anion Transporter 1; Naproxen; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 2; Probenecid; Proton Pump Inhibitors; Quinidine; Rifampin; Verapamil	2017
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases. Drug design, development and therapy, 2017, Volume: 11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Celecoxib; Cimetidine; Delayed-Action Preparations; Diffusion; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Gastric Juice; Histamine H2 Antagonists; Ibuprofen; Inflammation; Kinetics; Models, Chemical; Nanocapsules; Nanotechnology; Naproxen; Polymers; Solubility; Technology, Pharmaceutical	2017
Modulatory Effects of Metformin Alone and in Combination with Cimetidine and Ibuprofen on T Cell-related Parameters in a Breast Cancer Model. Iranian journal of allergy, asthma, and immunology, 2021, Sep-28, Volume: 20, Issue:5 Topics: Animals; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Cimetidine; Disease Models, Animal; Female; Humans; Ibuprofen; Immunomodulation; Metformin; Mice; T-Lymphocyte Subsets; T-Lymphocytes	2021
Cimetidine and Ibuprofen Modulate T Cell Responses in a Mouse Model of Breast Cancer. Asian Pacific journal of cancer prevention : APJCP, 2022, Jun-01, Volume: 23, Issue:6 Topics: Animals; Cimetidine; Disease Models, Animal; Forkhead Transcription Factors; Ibuprofen; Mice; Mice, Inbred BALB C; Neoplasms; Nuclear Receptor Subfamily 1, Group F, Member 3; T-Lymphocytes, Regulatory; Transforming Growth Factor beta	2022