cimetidine and guaifenesin

cimetidine has been researched along with guaifenesin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199014 (43.75)18.7374
1990's7 (21.88)18.2507
2000's4 (12.50)29.6817
2010's7 (21.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Durham, RM; Shapiro, MJ1
Guslandi, M2
Cheli, R; Molinari, F; Parodi, MC1
Hotta, K; Ishihara, K; Kakei, M; Ohara, S; Okabe, H1
Ito, M; Suzuki, Y; Tanaka, T1
Dai, S; Ho, MM; Ogle, CW1
Kristensen, M; Nilsson, T1
Carson, SA; Chopra, SK; Tashkin, DP1
Meeroff, JC1
Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM1
Kyogoku, K; Mori, Y; Nakazima, M; Shinozaki, A; Suwa, T1
West, GB1
Hiroi, J; Honda, F; Katsuki, S; Ohtsuka, M; Seki, J1
Azuumi, Y; Hotta, K; Ishihara, K; Kakei, M; Ohara, S; Okabe, H1
Kagoshima, M; Kodaira, H; Shimada, H1
Kamishiro, T; Masuda, M; Matsukura, H; Uchida, A1
Clement, P; De Waele, M; Smitz, J; Wang, D1
Konno, K; Nakata, J; Takeyama, K; Tamaoki, J1
Chiyotani, A; Konno, K; Nakata, J; Takeyama, K; Tamaoki, J1
Chang, QD; Wan, JL; Wang, CL1
Hirano, H; Majima, Y; Sakakura, Y; Shimizu, T1
Arnaud, P; Botham, R; Lenfant, B; Pachot, J; Pontier, C1
Hattori, R; Majima, Y; Shimizu, S; Shimizu, T1
Batista, LM; Calvo, TR; de Almeida, AB; de Pietro Magri, L; Souza Brito, AR; Toma, W; Vilegas, W1
Arambewela, LS; Arawwawala, LD; Thabrew, MI1
de Andrade, SF; Klein JĂșnior, LC; Lemos, M; Niero, R; Santin, JR1
Higuchi, K; Murano, M; Tokioka, S; Umegaki, E; Yoda, Y1
Diebel, LN; Hall-Zimmerman, L; Liberati, DM1

Reviews

3 review(s) available for cimetidine and guaifenesin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Stress gastritis revisited.
    The Surgical clinics of North America, 1991, Volume: 71, Issue:4

    Topics: Antacids; Bicarbonates; Cimetidine; Epithelium; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Intercellular Junctions; Mucus; Prostaglandins; Stress, Physiological; Sucralfate

1991
Review: effect of anti-ulcer drugs on gastric mucous barrier and possible cyclic AMP involvement.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Carbenoxolone; Cimetidine; Cyclic AMP; Gastric Mucosa; Gefarnate; Humans; Mucus; Parasympatholytics; Pentagastrin; Prostaglandins

1980

Trials

1 trial(s) available for cimetidine and guaifenesin

ArticleYear
The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis.
    Acta oto-rhino-laryngologica Belgica, 1996, Volume: 50, Issue:1

    Topics: Adult; Airway Resistance; Anti-Allergic Agents; Bronchodilator Agents; Budesonide; Cimetidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Mucus; Nasal Provocation Tests; Phthalazines; Pregnenediones; Rhinitis, Allergic, Seasonal

1996

Other Studies

28 other study(ies) available for cimetidine and guaifenesin

ArticleYear
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Cimetidine, carbenoxolone and gastric mucus.
    Gut, 1988, Volume: 29, Issue:9

    Topics: Carbenoxolone; Cimetidine; Gastric Mucosa; Glycyrrhetinic Acid; Humans; Mucus

1988
Cimetidine and cytoprotection.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 121

    Topics: Cimetidine; Gastric Acid; Gastric Mucosa; Humans; Mucus

1986
Effect of cimetidine on gastric mucus glycoprotein biosynthesis.
    Digestion, 1986, Volume: 34, Issue:2

    Topics: Animals; Cimetidine; Gastric Mucosa; Glycoproteins; In Vitro Techniques; Male; Mucus; Rats; Rats, Inbred Strains

1986
Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Gastric Mucosa; Glycoproteins; Male; Mucus; Polyenes; Proglumide; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing

1986
Morphine enhances gastric mucus synthesis in rats.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Animals; Atropine; Cimetidine; Fentanyl; Gastric Mucosa; Male; Morphine; Mucus; Naloxone; Rats

1986
Mucus secretion in hypertrophic, hypersecretory, protein-losing gastropathy.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:2

    Topics: Cimetidine; Fucose; Gastric Juice; Gastritis; Gastritis, Hypertrophic; Hexosamines; Humans; Male; Middle Aged; Mucus; Proteins; Saliva; Sodium

1985
Effect of intravenous cimetidine on mucociliary transport in anesthetized dogs.
    European journal of respiratory diseases, 1982, Volume: 63, Issue:4

    Topics: Aerosols; Anesthesia, Intravenous; Animals; Cilia; Cimetidine; Depression, Chemical; Dogs; Guanidines; Histamine H2 Antagonists; Injections, Intravenous; Mucus; Receptors, Histamine H2; Trachea

1982
Ulcer disease of the upper gastrointestinal tract.
    Hospital practice (Office ed.), 1984, Volume: 19, Issue:10

    Topics: Aluminum; Antacids; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Gastrectomy; Gastric Acid; Gastrins; Gastrointestinal Hormones; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Intestinal Absorption; Metoclopramide; Mucus; Parasympatholytics; Ranitidine; Smoking; Stomach Ulcer; Sucralfate; Vagotomy

1984
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
    International archives of allergy and applied immunology, 1984, Volume: 74, Issue:4

    Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea

1984
Cytoprotective effect of SU-88, an anti-ulcer agent, in the rat.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cell Survival; Chalcone; Chalcones; Cimetidine; Dinoprostone; Ethanol; Gastric Mucosa; Glycoproteins; Hydrochloric Acid; Indomethacin; Male; Mucus; Propiophenones; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer

1984
Testing for drugs inhibiting the formation of gastric ulcers.
    Journal of pharmacological methods, 1982, Volume: 8, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Cold Temperature; Copper; Indomethacin; Mucus; Organometallic Compounds; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Salicylates; Stomach Ulcer; Stress, Physiological

1982
Effect of cimetidine on gastric tissue mucous contents in rats subjected to stress.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:1

    Topics: Animals; Cimetidine; Gastric Mucosa; Guanidines; Hexosamines; Hexoses; Male; Mucus; Rats; Stress, Physiological

1981
[Effects of cimetidine and cetraxate on the biosynthetic activity of mucus glycoproteins in organ culture of rat gastric mucosa (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1981, Volume: 78, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cyclohexanecarboxylic Acids; Gastric Mucosa; Glycoproteins; Guanidines; Male; Mucus; Organ Culture Techniques; Rats; Tranexamic Acid

1981
[Effects of FRG-8813, a new histamine H2-receptor antagonist, on gastric mucus in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1994, Volume: 104, Issue:5

    Topics: Acetamides; Administration, Oral; Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Mucosa; Hexoses; Histamine H2 Antagonists; Male; Mucus; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley

1994
Effects of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Dinoprostone; Gastric Mucosa; Hexosamines; Hexoses; Indomethacin; Male; Mucus; Omeprazole; Prostaglandins; Rats; Rats, Sprague-Dawley

1994
Effect of oxitropium bromide on histamine-induced airway goblet cell secretion.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:1

    Topics: Administration, Inhalation; Aerosols; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Histocytochemistry; Injections, Intravenous; Male; Mucus; Muscarinic Antagonists; Piperidines; Pyrilamine; Receptors, Histamine; Scopolamine Derivatives; Trachea; Vagus Nerve

1996
Histamine H2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Animals; Asthma; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine N-Methyltransferase; Male; Methylhistamines; Mucus; Piperidines; Pyrilamine; Recombinant Proteins; Trachea

1997
Effect of tetramethylpyrazine on reserpine-induced gastric lesion in rats.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Mucus; Pyrazines; Rats; Rats, Sprague-Dawley; Reserpine; Stomach; Stomach Ulcer

1998
A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:5

    Topics: Animals; Antigens; Chlorpheniramine; Chromones; Cimetidine; Dexamethasone; Eosinophils; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Immune Sera; Immunization; Leukotriene Antagonists; Lipopolysaccharides; Male; Mucus; Nasal Mucosa; Neutrophils; Ovalbumin; Rats; Rats, Inbred F344; Rhinitis, Allergic, Perennial

2000
HT29-MTX and Caco-2/TC7 monolayers as predictive models for human intestinal absorption: role of the mucus layer.
    Journal of pharmaceutical sciences, 2001, Volume: 90, Issue:10

    Topics: Administration, Oral; Biological Transport, Active; Caco-2 Cells; Cell Membrane Permeability; Cell Size; Cimetidine; Diffusion; Forecasting; HT29 Cells; Humans; Intercellular Junctions; Intestinal Absorption; Intestinal Mucosa; Methotrexate; Microscopy, Electron, Scanning; Microvilli; Models, Biological; Mucus; Sumatriptan

2001
A mechanism of antigen-induced goblet cell degranulation in the nasal epithelium of sensitized rats.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:1

    Topics: Animals; Antigens; Atropine; Cell Degranulation; Chromones; Cimetidine; Eosinophils; Histamine; Indomethacin; Mucus; Nasal Mucosa; Neutrophils; Ovalbumin; Rats

2003
Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Bethanechol; Cimetidine; Disease Models, Animal; Eriocaulaceae; Ethanol; Gastric Juice; Gastrointestinal Contents; Hydrogen-Ion Concentration; Indomethacin; Lansoprazole; Male; Mice; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

2004
Gastroprotective activity of Trichosanthes cucumerina in rats.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Ethanol; Female; Gastric Juice; Gastric Mucosa; Histamine Antagonists; Hydrogen-Ion Concentration; Indomethacin; Male; Mucus; Plant Components, Aerial; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Stomach Ulcer; Sucralfate; Trichosanthes

2010
Antiulcer effects of Achyrocline satureoides (Lam.) DC (Asteraceae) (Marcela), a folk medicine plant, in different experimental models.
    Journal of ethnopharmacology, 2010, Jul-20, Volume: 130, Issue:2

    Topics: Achyrocline; Animals; Anti-Ulcer Agents; Brazil; Cimetidine; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Indomethacin; Medicine, Traditional; Mucus; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer

2010
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer; Piperidines; Prostaglandins; Rats; Rats, Sprague-Dawley

2010
H2 blockers decrease gut mucus production and lead to barrier dysfunction in vitro.
    Surgery, 2011, Volume: 150, Issue:4

    Topics: Bacterial Adhesion; Cimetidine; Critical Illness; Escherichia coli; Histamine H2 Antagonists; HT29 Cells; Humans; In Vitro Techniques; Interleukin-6; Intestinal Mucosa; Mucins; Mucus; Tumor Necrosis Factor-alpha

2011