cimetidine has been researched along with coumarin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Butler, K; Fried, A; Marshall, ME | 1 |
| Fentem, JH; Fry, JR | 1 |
| Hennig, FW; Herrmann, R; Manegold, C; Matthiessen, W; Maurer, B | 1 |
| Amato, R; Dexeus, FH; Dozier, N; Fitz, K; Logothetis, CJ; Reuben, JM; Sella, A | 1 |
| Butler, K; Cantrell, J; Marshall, ME; Mendelsohn, L; Wiseman, C | 1 |
| Davenport, Y; Tseng, A; Venook, AP | 1 |
| Cibull, M; Eichhorn, T; Jennings, CD; Marshall, ME; Rhoades, J; Riley, LK; Thompson, J | 1 |
| Butler, K; Cantrell, J; Harvey, J; Macdonald, J; Marshall, ME; Mendelsohn, L | 1 |
| Ernstoff, MS; Kirkwood, JM | 1 |
| Butler, K; Cantrell, J; Macdonald, JS; Marshall, ME; Mendelsohn, L; Riley, L; Taylor, R; Wiseman, C | 1 |
| Langvad, E; Pedersen, L; Rose, C | 1 |
| Bueschen, A; Butler, K; Edmonds, K; Markiewicz, M; Marshall, ME; Mohler, JL; Ryles, M; Urban, D; Weiss, L; Williams, B | 1 |
| Flamm, J; Ludwig, H; Micksche, M; Sagaster, P | 1 |
1 review(s) available for cimetidine and coumarin
| Article | Year |
|---|---|
An updated review of the clinical development of coumarin (1,2-benzopyrone) and 7-hydroxycoumarin.
Topics: Adult; Aged; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Cimetidine; Coumarins; Drug Therapy, Combination; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome; Umbelliferones | 1994 |
3 trial(s) available for cimetidine and coumarin
| Article | Year |
|---|---|
Phase I evaluation of coumarin (1,2-benzopyrone) and cimetidine in patients with advanced malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Coumarins; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Radiography | 1991 |
Phase II trial of coumarin and cimetidine in advanced renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cimetidine; Coumarins; Drug Evaluation; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Pleural Neoplasms; Survival Rate | 1990 |
Randomised study using IFN-alpha versus IFN-alpha plus coumarin and cimetidine for treatment of advanced renal cell cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cimetidine; Coumarins; Female; Humans; Interferon alpha-2; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Recombinant Proteins | 1995 |
16 other study(ies) available for cimetidine and coumarin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of cimetidine on the metabolism of coumarin by rat, gerbil and human liver microsomes.
Topics: Animals; Cimetidine; Coumarins; Drug Interactions; Gerbillinae; Humans; Male; Microsomes, Liver; Models, Biological; Phenobarbital; Rats; Rats, Inbred Strains; Umbelliferones | 1991 |
Phase II study of coumarin and cimetidine in patients with metastatic renal cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cimetidine; Coumarins; Drug Evaluation; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Kidney Neoplasms; Lymphocyte Activation; Male; Middle Aged; Remission Induction; T-Lymphocytes, Regulatory | 1990 |
Treatment of advanced malignant melanoma with coumarin and cimetidine: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Coumarins; Female; Humans; Male; Melanoma; Middle Aged; Pilot Projects | 1989 |
Activity of coumarin and cimetidine in metastatic renal cell carcinoma.
Topics: Carcinoma, Renal Cell; Cimetidine; Coumarins; Drug Evaluation; Drug Therapy, Combination; Humans; Kidney Neoplasms | 1989 |
Effects of coumarin (1,2-benzopyrone) and cimetidine on peripheral blood lymphocytes, natural killer cells, and monocytes in patients with advanced malignancies.
Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Coumarins; Female; Humans; Killer Cells, Natural; Lymphocytes; Male; Middle Aged; Monocytes; Neoplasms | 1989 |
Treatment of non-small cell lung cancer with coumarin and cimetidine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cimetidine; Coumarins; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1987 |
Coumarin plus cimetidine: yet another angle for therapy of renal cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cimetidine; Coumarins; Humans; Kidney Neoplasms; Pilot Projects | 1987 |
Treatment of metastatic renal cell carcinoma with coumarin (1,2-benzopyrone) and cimetidine: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cimetidine; Coumarins; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nephrectomy; Pilot Projects; Remission Induction | 1987 |
Combined treatment of advanced malignant melanoma with coumarin and cimetidine. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Coumarins; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Skin Neoplasms | 1987 |