cimetidine has been researched along with bupivacaine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Dundas, CR; Noble, DW; Smith, KJ | 1 |
| Brighouse, D; Morgan, B; O'Sullivan, GM; Reynolds, F; Smith, M | 1 |
| Collier, PS; Flynn, RJ; McClean, E; Moore, J | 1 |
| Jantunen, ME; Lindberg, RL; Pihlajamäki, KK | 1 |
| Brashear, WT; Brown, DE; Kuhnert, BR; Kuhnert, PM; Syracuse, CD; Zuspan, KJ | 1 |
| Honda, K; Inomata, S; Nakamura, T; Tanaka, E | 1 |
4 trial(s) available for cimetidine and bupivacaine
| Article | Year |
|---|---|
Effects of H-2 antagonists on the elimination of bupivacaine.
Topics: Bupivacaine; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Kinetics; Male; Metabolic Clearance Rate; Ranitidine | 1987 |
H2 antagonists and bupivacaine clearance.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Cimetidine; Female; Histamine H2 Antagonists; Humans; Pregnancy; Ranitidine; Time Factors | 1988 |
Does pretreatment with cimetidine and ranitidine affect the disposition of bupivacaine?
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Cimetidine; Female; Humans; Pneumonia, Aspiration; Pregnancy; Premedication; Ranitidine | 1989 |
Lack of effect of cimetidine on the pharmacokinetics of bupivacaine in healthy subjects.
Topics: Adult; Bupivacaine; Cimetidine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate | 1988 |
12 other study(ies) available for cimetidine and bupivacaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Lack of influence of cimetidine on bupivacaine levels during parturition.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Biotransformation; Bupivacaine; Cesarean Section; Cimetidine; Citrates; Citric Acid; Female; Humans; Preanesthetic Medication; Pregnancy | 1987 |
Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.
Topics: Amides; Anesthetics, Local; Bupivacaine; Cells, Cultured; Cimetidine; Clonidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Lidocaine; Microsomes, Liver; Midazolam; Premedication; Ropivacaine; Thiamylal; Vecuronium Bromide | 2006 |