cimetidine has been researched along with allopurinol in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (19.15) | 18.7374 |
1990's | 10 (21.28) | 18.2507 |
2000's | 15 (31.91) | 29.6817 |
2010's | 13 (27.66) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Endou, H; Kobayashi, Y; Ohshiro, N; Sasaki, T; Sekine, T; Shibusawa, A; Tokuyama, S; Yamamoto, T | 1 |
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Bircher, J; Brandes, A; Compagnone, D; Hille, H; Münch, B; Ullrich, D | 1 |
Salim, AS | 6 |
Millard, J; Zimmerman, J | 1 |
Friedl, HP; Till, GO; Trentz, O; Ward, PA | 1 |
Murata, K; Noda, K; Samejima, M; Tagawa, K | 1 |
Chiba, S; Horiuchi, A; Iwatsuki, K; Oguchi, H; Yonekura, H | 1 |
Birkett, DJ; Kjellen, G; Lelo, A; Miners, JO | 1 |
Tarnok, I; Tarnok, Z | 1 |
Handa, SP | 1 |
Granger, DN; Korthuis, RJ; Taylor, AE; Townsley, MI | 1 |
Champion, GD; Day, RO; Graham, GG; Lee, E | 1 |
Byrne, PJ; Caldwell, MT; Gorey, TF; Hennessy, TP; Stuart, RC | 1 |
Byrne, PJ; Flynn, R; Gorey, TF; Hennessy, TP; Kay, E; McBennett, S; Stuart, RC | 1 |
Osakabe, N; Osawa, T; Sanbongi, C; Takizawa, T; Yamagishi, M | 1 |
Huang, H; Salahudeen, AK | 1 |
Ayalasomayajula, S; Bizot, MN; Dieterich, HA; Dole, WP; Howard, D; Tchaloyan, S; Yeh, CM | 1 |
Chen, H; Hu, JP; Li, Y; Sheng, L | 1 |
Getachew, H; Shibeshi, W; Tadesse, Y | 1 |
2 review(s) available for cimetidine and allopurinol
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Anti-rheumatic drug interactions.
Topics: Adrenergic beta-Antagonists; Allopurinol; Animals; Antacids; Anti-Inflammatory Agents; Anticoagulants; Cimetidine; Diuretics; Drug Combinations; Drug Interactions; Glucocorticoids; Gold; Humans; Hypoglycemic Agents; Penicillamine; Probenecid; Sulfinpyrazone; Vasodilator Agents | 1984 |
5 trial(s) available for cimetidine and allopurinol
Article | Year |
---|---|
Allopurinol and dimethyl sulfoxide improve treatment outcomes in smokers with peptic ulcer disease.
Topics: Adult; Alcohol Drinking; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Double-Blind Method; Duodenal Ulcer; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Male; Middle Aged; Prospective Studies; Recurrence; Smoking; Time Factors | 1992 |
Oxygen-derived free radicals and the prevention of duodenal ulcer relapse: a new approach.
Topics: Allopurinol; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Follow-Up Studies; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Male; Middle Aged; Prospective Studies; Random Allocation; Recurrence; Smoking | 1990 |
Role of free radical scavengers in the management of refractory duodenal ulceration. A new approach.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Female; Free Radical Scavengers; Humans; Hydroxyl Radical; Male; Middle Aged; Prospective Studies; Recurrence; Smoking; Xanthine Oxidase | 1994 |
The relationship between Helicobacter pylori and oxygen-derived free radicals in the mechanism of duodenal ulceration.
Topics: Adult; Aged; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Free Radical Scavengers; Free Radicals; Helicobacter Infections; Helicobacter pylori; Humans; Life Tables; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Reactive Oxygen Species; Recurrence; Treatment Outcome | 1993 |
A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects.
Topics: Adolescent; Adult; Allopurinol; Amides; Antihypertensive Agents; Celecoxib; Cimetidine; Cyclooxygenase Inhibitors; Drug Interactions; Female; Fumarates; Gout Suppressants; Histamine H2 Antagonists; Humans; Hypertension; Male; Middle Aged; Pyrazoles; Reference Values; Renin; Sulfonamides | 2008 |
40 other study(ies) available for cimetidine and allopurinol
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice.
Topics: Amino Acid Sequence; Animals; Chromosome Mapping; Cloning, Molecular; Gene Expression Regulation; Mice; Molecular Sequence Data; Organic Anion Transporters, Sodium-Independent; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations.
Topics: Adolescent; Adult; Age Factors; Allopurinol; Caffeine; Child; Cimetidine; Drug Interactions; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosis; Male; Phenytoin; Smoking; Theophylline | 1992 |
A possible new approach to the problem of refractory peptic ulceration. A role for free radical scavengers?
Topics: Adult; Allopurinol; Chronic Disease; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Free Radical Scavengers; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Male; Middle Aged; Stomach Ulcer | 1991 |
H2-antagonist inhibition of human neutrophil superoxide anion synthesis.
Topics: Cimetidine; Dose-Response Relationship, Drug; Free Radicals; Humans; Immunity, Cellular; NADH, NADPH Oxidoreductases; Neutrophils; Ranitidine; Superoxides; Xanthine Oxidase | 1989 |
Roles of histamine, complement and xanthine oxidase in thermal injury of skin.
Topics: Animals; Burns; Cimetidine; Complement Inactivator Proteins; Complement System Proteins; Cromolyn Sodium; Edema; Elapid Venoms; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Hydroxides; Hydroxyl Radical; Kinetics; Male; Radioimmunoassay; Rats; Skin; Superoxides; Uric Acid; Xanthine Oxidase | 1989 |
Pharmacokinetic analysis of single- or multiple-dose plasma drug concentration data with a microcomputer using multi-fraction absorption models.
Topics: Administration, Oral; Allopurinol; Bayes Theorem; Cimetidine; Delayed-Action Preparations; Diltiazem; Intestinal Absorption; Microcomputers; Models, Biological; Nalidixic Acid; Pharmaceutical Preparations; Pharmacokinetics; Regression Analysis; Software; Sulfisoxazole | 1989 |
Allopurinol stimulates pancreatic exocrine secretion in the dog.
Topics: Allopurinol; Animals; Atropine; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Male; Pancreas; Pancreatic Juice; Secretin; Sulpiride | 1989 |
Paraxanthine metabolism in humans: determination of metabolic partial clearances and effects of allopurinol and cimetidine.
Topics: Acetylation; Adult; Allopurinol; Caffeine; Cimetidine; Cytochrome P-450 Enzyme System; Humans; Kidney; Male; Metabolic Clearance Rate; Theophylline | 1989 |
Interaction of cimetidine and histamine with superoxide generated in a cell-free system and in neutrophils.
Topics: Cell-Free System; Cimetidine; Histamine; Humans; Neutrophils; Superoxides; Xanthine Oxidase | 1987 |
Drug-induced acute interstitial nephritis: report of 10 cases.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cephaloridine; Cimetidine; Female; Fenoprofen; Humans; Indomethacin; Kidney; Male; Middle Aged; Nephritis, Interstitial; Penicillins | 1986 |
The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability.
Topics: Allopurinol; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Capillary Permeability; Catalase; Cimetidine; Dimethyl Sulfoxide; Diphenhydramine; Dogs; Female; Free Radicals; Ischemia; Male; Muscles; Osmotic Pressure; Oxygen; Superoxide Dismutase; Vascular Resistance | 1985 |
Oxygen-derived free radical scavengers: a new approach to the problem of refractory peptic ulceration.
Topics: Adult; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Female; Free Radical Scavengers; Free Radicals; Humans; Male; Middle Aged; Peptic Ulcer | 1993 |
Microvascular changes in experimental gastric stress ulceration: the influence of allopurinol, cimetidine, and misoprostol.
Topics: Allopurinol; Animals; Capillaries; Cimetidine; Female; Gastric Mucosa; Microcirculation; Microscopy, Electron, Scanning; Misoprostol; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Physiological; Vascular Patency | 1993 |
Stress ulceration and gastric mucosal cell kinetics: the influence of prophylaxis against acute stress ulceration.
Topics: Allopurinol; Animals; Cell Division; Cell Movement; Cimetidine; DNA; Gastric Mucosa; Kinetics; Male; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 1993 |
Effects of polyphenol substances derived from Theobroma cacao on gastric mucosal lesion induced by ethanol.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cacao; Chromatography, High Pressure Liquid; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Flavonoids; Gastric Mucosa; Lipid Peroxidation; Male; Peroxidase; Phenols; Polymers; Polyphenols; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sucralfate; Thiobarbituric Acid Reactive Substances; Uric Acid; Vitamin E; Xanthine Oxidase | 1998 |
Cold induces catalytic iron release of cytochrome P-450 origin: a critical step in cold storage-induced renal injury.
Topics: Adenosine; Allopurinol; Catalysis; Cimetidine; Cold Temperature; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Inhibitors; Glutathione; Humans; Insulin; Iron; Kidney; Kidney Tubules; Organ Preservation; Organ Preservation Solutions; Raffinose; Urothelium | 2002 |
[Metabolism of nicousamide in rat and human liver in vitro].
Topics: Adenosine Monophosphate; Allopurinol; Aniline Compounds; Animals; Cimetidine; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Cytochrome-B(5) Reductase; Cytosol; Dicumarol; Enzyme Inhibitors; Female; Humans; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Propylthiouracil; Rats; Rats, Sprague-Dawley; Steroid 21-Hydroxylase; Xanthine Oxidase | 2008 |
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Antifungal Agents; Antihypertensive Agents; Ceftazidime; Cimetidine; Creatinine; Cross-Sectional Studies; Digoxin; Diuretics; Drug Dosage Calculations; Drug Prescriptions; Enalapril; Ethiopia; Female; Fluconazole; Gout Suppressants; Hospitalization; Humans; Male; Medication Errors; Middle Aged; Pharmaceutical Preparations; Prospective Studies; Renal Insufficiency, Chronic; Severity of Illness Index; Spironolactone; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Young Adult | 2015 |