Page last updated: 2024-09-03

cimadronate and zoledronic acid

cimadronate has been researched along with zoledronic acid in 5 studies

Compound Research Comparison

Studies
(cimadronate)
Trials
(cimadronate)
Recent Studies (post-2010)
(cimadronate)
Studies
(zoledronic acid)
Trials
(zoledronic acid)
Recent Studies (post-2010) (zoledronic acid)
105344,1086202,610

Protein Interaction Comparison

ProteinTaxonomycimadronate (IC50)zoledronic acid (IC50)
Carbonic anhydrase 12Homo sapiens (human)0.316
Geranylgeranyl pyrophosphate synthaseHomo sapiens (human)0.318
Carbonic anhydrase 2Homo sapiens (human)0.062
72 kDa type IV collagenaseHomo sapiens (human)7
Farnesyl pyrophosphate synthaseHomo sapiens (human)0.2144
Farnesyl diphosphate synthaseEscherichia coli K-121.1
Farnesyl pyrophosphate synthase Leishmania donovani0.11
Geranylgeranyl pyrophosphate synthaseSaccharomyces cerevisiae S288C0.424
Carbonic anhydrase 9Homo sapiens (human)5.323
Carbonic anhydrase 14Homo sapiens (human)0.092

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruchhaus, I; Chan, JM; Croft, SL; Flessner, RM; Ghosh, S; Kemp, RG; Kendrick, H; Kobayashi, S; Lea, CR; Lewis, JC; Loftus, TC; Meints, GA; Nozaki, T; Oldfield, E; Tovian, ZS1
Hall, P; Hudock, MP; Leon, A; Liu, L; Morita, CT; Oldfield, E; Puan, KJ; Studer, D; Yang, Y; Yin, F1
Barnett, BL; Dunford, JE; Ebetino, FH; Kavanagh, KL; Kwaasi, AA; Oppermann, U; Rogers, MJ; Russell, RG1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fujii, Y; Fukui, I; Kijima, T; Okubo, Y; Suyama, T; Yonese, J1

Other Studies

5 other study(ies) available for cimadronate and zoledronic acid

ArticleYear
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Antimalarials; Antiprotozoal Agents; Cell Line; Cricetinae; Diphosphonates; Entamoeba histolytica; Entamoebiasis; Humans; In Vitro Techniques; Liver Abscess; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship

2004
Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Anti-Bacterial Agents; Cluster Analysis; Diphosphonates; Drug Synergism; Escherichia coli K12; Fosfomycin; Gene Expression; Geranyltranstransferase; Models, Molecular; Oligonucleotide Array Sequence Analysis; Quantitative Structure-Activity Relationship; Terpenes

2006
Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Binding Sites; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Models, Molecular; Molecular Structure; Nitrogen; Stereoisomerism; Structure-Activity Relationship; Time Factors

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Lung and bone metastases from renal cell carcinoma responsive to bisphosphonates: a case report.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:6

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Humans; Imidazoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Pamidronate; Zoledronic Acid

2008