cimadronate has been researched along with tipifarnib in 1 studies
| Studies (cimadronate) | Trials (cimadronate) | Recent Studies (post-2010) (cimadronate) | Studies (tipifarnib) | Trials (tipifarnib) | Recent Studies (post-2010) (tipifarnib) |
|---|---|---|---|---|---|
| 105 | 3 | 4 | 309 | 92 | 94 |
| Protein | Taxonomy | cimadronate (IC50) | tipifarnib (IC50) |
|---|---|---|---|
| Chain B, Protein farnesyltransferase beta subunit | Rattus norvegicus (Norway rat) | 0.0007 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2.88 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Bos taurus (cattle) | 0.5503 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 2.2237 | |
| Protein farnesyltransferase subunit beta | Bos taurus (cattle) | 0.0006 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.0019 | |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | 10 | |
| Geranylgeranyl transferase type-1 subunit beta | Bos taurus (cattle) | 1.1 | |
| Protein farnesyltransferase alpha subunit | Plasmodium falciparum (malaria parasite P. falciparum) | 0.017 | |
| CAAX farnesyltransferase subunit beta | Plasmodium falciparum (malaria parasite P. falciparum) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashihara, E; Fuchida, S; Inaba, T; Ochiai, N; Okamoto, M; Okano, A; Shimazaki, C; Uchida, R; Yamada, N | 1 |
1 other study(ies) available for cimadronate and tipifarnib
| Article | Year |
|---|---|
Nitrogen-containing bisphosphonate incadronate augments the inhibitory effect of farnesyl transferase inhibitor tipifarnib on the growth of fresh and cloned myeloma cells in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Farnesyltranstransferase; Humans; Multiple Myeloma; Quinolones; Tumor Cells, Cultured | 2005 |