cimadronate has been researched along with mevalonic acid in 6 studies
| Studies (cimadronate) | Trials (cimadronate) | Recent Studies (post-2010) (cimadronate) | Studies (mevalonic acid) | Trials (mevalonic acid) | Recent Studies (post-2010) (mevalonic acid) |
|---|---|---|---|---|---|
| 105 | 3 | 4 | 3,810 | 33 | 922 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Croucher, PI; Helfrich, MH; Rogers, MJ; Russell, RG; Shipman, CM | 1 |
| Fujita, T; Fukuyama, R; Izumo, N; Koida, M; Meguro, T; Nakamuta, H; Yasutomi, C | 1 |
| Iguchi, T; Ikeda, Y; Kizaki, M; Miyakawa, Y; Yamamoto, K | 1 |
| Hirano, K; Iguchi, K; Nakano, T; Usui, S | 1 |
| Endo, N; Hotta, T; Ito, T; Kawashima, H; Nakano, K; Ogose, A; Tamura, K | 1 |
| Ishikawa, C; Kawakami, H; Masuda, M; Matsuda, T; Mori, N; Ohshiro, K; Ohta, T; Okudaira, T; Tanaka, Y; Tomita, M | 1 |
6 other study(ies) available for cimadronate and mevalonic acid
| Article | Year |
|---|---|
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Lovastatin; Mevalonic Acid; Multiple Myeloma; Protein Prenylation; Tumor Cells, Cultured | 1998 |
Incadronate and etidronate accelerate phosphate-primed mineralization of MC4 cells via ERK1/2-Cbfa1 signaling pathway in a Ras-independent manner: further involvement of mevalonate-pathway blockade for incadronate.
Topics: Animals; Blotting, Western; Calcification, Physiologic; Calcium; Cell Line; Cell Nucleus; Diphosphonates; Etidronic Acid; Genes, ras; Mevalonic Acid; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; Ovariectomy; Phosphates; Transcription Factors | 2001 |
Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway.
Topics: Apoptosis; Cell Division; Cell Line, Tumor; Checkpoint Kinase 1; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Imidazoles; Interleukin-6; MAP Kinase Signaling System; Mevalonic Acid; Multiple Myeloma; Phosphorylation; Protein Kinases; S Phase; Signal Transduction; Stromal Cells | 2003 |
Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.
Topics: Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cytosol; Diphosphonates; Enzyme Inhibitors; Humans; Leucine; Male; Mevalonic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; rap1 GTP-Binding Proteins | 2006 |
Effect of incadronate on proliferation of mesenchymal tumor cells with or without activated Ras mutation.
Topics: Animals; Apoptosis; Autoradiography; Bone Density Conservation Agents; Cell Proliferation; Diphosphonates; Farnesyltranstransferase; Genes, ras; Humans; Mesenchymoma; Mevalonic Acid; Mutation; Polymerase Chain Reaction | 2005 |
Bisphosphonate incadronate inhibits growth of human T-cell leukaemia virus type I-infected T-cell lines and primary adult T-cell leukaemia cells by interfering with the mevalonate pathway.
Topics: Aged; Animals; Antimetabolites; Apoptosis; Biomarkers; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Female; Human T-lymphotropic virus 1; Humans; Inhibitor of Apoptosis Proteins; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Leukemia, T-Cell; Male; Mevalonic Acid; Mice; Mice, SCID; Microtubule-Associated Proteins; Middle Aged; Neoplasm Proteins; Neoplasm Transplantation; Signal Transduction; Survivin; T-Lymphocytes | 2007 |