cilostazol and theophylline

cilostazol has been researched along with theophylline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bristol, JA; Cain, MH; Weishaar, RE1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Fujimura, M; Kita, T; Matsuda, T; Myou, S; Tachibana, H1
Fujimura, M; Hashimoto, T; Kamio, Y; Matsuda, T; Myou, S1
Nagai, H; Tanaka, H; Uno, T1
Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M1
Hasegawa, T; Hiramatsu, K; Ito, Y; Kitaichi, K; Kume, H; Shibata, E; Shimizu, Y; Suzuki, R; Takagi, K; Takeuchi, M; Yamaki, K; Yoshida, N1
El Solh, AA; Saliba, R1
Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y1
Ebihara, S; Ebihara, T; Gui, P; Kohzuki, M; Osaka, K; Sumi, Y1
Cho, JG; Jeong, HK; Jin, IT; Lee, KH; Park, HW; Yoon, N1

Reviews

4 review(s) available for cilostazol and theophylline

ArticleYear
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic prevention of aspiration pneumonia: a systematic review.
    The American journal of geriatric pharmacotherapy, 2007, Volume: 5, Issue:4

    Topics: Aged; Amantadine; Angiotensin-Converting Enzyme Inhibitors; Cabergoline; Capsaicin; Cilostazol; Controlled Clinical Trials as Topic; Ergolines; Humans; Pneumonia, Aspiration; Risk Factors; Sensory System Agents; Tetrazoles; Theophylline

2007
Thermal taste and anti-aspiration drugs: a novel drug discovery against pneumonia.
    Current pharmaceutical design, 2014, Volume: 20, Issue:16

    Topics: Animals; Cilostazol; Drug Discovery; Humans; Pneumonia, Aspiration; Taste; Tetrazoles; Theophylline; Thermoreceptors; Thermosensing

2014

Trials

1 trial(s) available for cilostazol and theophylline

ArticleYear
Effect of a phosphodiesterase 3 inhibitor, cilostazol, on bronchial hyperresponsiveness in elderly patients with asthma.
    International archives of allergy and immunology, 1997, Volume: 114, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Aged; Asthma; Bronchial Hyperreactivity; Cilostazol; Cyclic Nucleotide Phosphodiesterases, Type 3; Double-Blind Method; Female; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Respiratory Function Tests; Tetrazoles; Theophylline

1997

Other Studies

10 other study(ies) available for cilostazol and theophylline

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Bronchoprotective effects of KF-19514 and cilostazol in guinea pigs in vivo.
    European journal of pharmacology, 1997, May-26, Volume: 327, Issue:1

    Topics: Animals; Bronchoconstriction; Bronchodilator Agents; Cilostazol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Naphthyridines; Phosphodiesterase Inhibitors; Tetrazoles; Theophylline

1997
Effects of isoenzyme selective phosphodiesterase inhibitors on bacterial lipopolysaccharide-induced bronchial hyperreactivity in guinea pigs.
    General pharmacology, 1998, Volume: 30, Issue:2

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cilostazol; Guinea Pigs; Isoenzymes; Lipopolysaccharides; Male; Neutrophils; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Quinolines; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha

1998
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines

1999
Differential effect of phosphodiesterase inhibitors on IL-13 release from peripheral blood mononuclear cells.
    Clinical and experimental immunology, 2001, Volume: 126, Issue:3

    Topics: Adult; Asthma; Cilostazol; Colforsin; Cyclic AMP; Dexamethasone; Humans; In Vitro Techniques; Interleukin-13; Kinetics; Leukocytes, Mononuclear; Male; Phosphodiesterase Inhibitors; Phytohemagglutinins; Rolipram; Tetrazoles; Theophylline

2001
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:10

    Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Hydroxy Acids; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion Injury; Superoxides; Tetrazoles; Theophylline

2011
Positive chronotropic effects of theophylline and cilostazol in patients with symptomatic sick sinus syndrome who have declined permanent pacing.
    Reviews in cardiovascular medicine, 2020, Sep-30, Volume: 21, Issue:3

    Topics: Aged; Cardiac Pacing, Artificial; Cardiovascular Agents; Cilostazol; Drug Substitution; Female; Heart Rate; Humans; Male; Middle Aged; Recovery of Function; Retrospective Studies; Sick Sinus Syndrome; Theophylline; Time Factors; Treatment Outcome; Treatment Refusal

2020