cilostazol and dipyridamole

cilostazol has been researched along with dipyridamole in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's1 (3.23)18.2507
2000's12 (38.71)29.6817
2010's14 (45.16)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Bristol, JA; Cain, MH; Weishaar, RE1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Kawai, C; Murohara, Y; Takatsu, Y; Yui, Y1
Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M1
Ito, H; Kimura, Y; Ozeki, Y; Sudo, T1
Inami, N; Iwasaka, T; Liu, Y; Nomura, S1
Bricmont, P; Cone, J; Czerwiec, FS; Fong, M; Kambayashi, J; Le, SN; Liu, Y; Shoaf, SE; Sun, B; Tao, L; Yoshitake, M1
Cone, J; Fong, M; Kambayashi, J; Li, H; Liu, Y; Yoshitake, M1
Iwata, M; Nakamura, T; Uchiyama, S; Yamazaki, M1
Liao, JK1
Bhatt, DL; Meadows, TA1
Iba, T1
Kesteven, P; McCaslin, J; Smout, J; Stansby, G1
Gomez, CR; Qureshi, AI1
Diener, HC; Weber, R1
Birnbaum, Y; Perez-Polo, JR; Ye, Y1
Kamal, AK; Khan, M1
Falcinelli, E; Gresele, P; Momi, S1
Baglin, TP; Eikelboom, JW; Hirsh, J; Spencer, FA; Weitz, JI1
Fisher, MJ; Liu, S; Paganini-Hill, A; Yang, F; Yu, C1
Rondina, MT; Weyrich, AS1
Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T1
Azarbal, A; Clavijo, L; Gaglia, MA1
Guo, ZN; Jin, H; Niu, PP; Xing, YQ; Yang, Y1
Liu, X; Zhang, JJ1
Longo, J; Minden, MD; Pandyra, AA; Penn, LZ; Schimmer, AD; Stachura, P1
Liu, S; Shah, J; Yu, W1

Reviews

15 review(s) available for cilostazol and dipyridamole

ArticleYear
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
    Circulation, 2007, Mar-27, Volume: 115, Issue:12

    Topics: Aspirin; Atherosclerosis; Cilostazol; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dipyridamole; Disease Susceptibility; Drug Interactions; Drug Therapy, Combination; Dyslipidemias; Hemorrhage; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome; Vasodilator Agents

2007
Clinical aspects of platelet inhibitors and thrombus formation.
    Circulation research, 2007, May-11, Volume: 100, Issue:9

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Cilostazol; Clopidogrel; Dipyridamole; Drug Resistance; Humans; Pentanoic Acids; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Stents; Tetrazoles; Thrombosis; Thromboxanes; Ticlopidine

2007
[Pretreatment with cilostazol protects against the vascular endothelial damage after ischemia/reperfusion].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:2

    Topics: Animals; Aspirin; Cilostazol; Dipyridamole; Endothelial Cells; Ischemic Preconditioning; Mice; Phosphodiesterase Inhibitors; Reperfusion Injury; Tetrazoles

2008
Oral antiplatelet agents and bleeding risk in relation to major cardiovascular surgery.
    Current drug safety, 2006, Volume: 1, Issue:3

    Topics: Aspirin; Cardiovascular Surgical Procedures; Cilostazol; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk; Tetrazoles; Ticlopidine

2006
Controversies and future perspectives of antiplatelet therapy in secondary stroke prevention.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10

    Topics: Aspirin; Blood-Brain Barrier; Cilostazol; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Humans; Lactones; Naphthalenes; Platelet Aggregation Inhibitors; Propionates; Pyridines; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Succinates; Tetrazoles; Thrombosis; Ticlopidine

2010
Protecting against ischemia-reperfusion injury: antiplatelet drugs, statins, and their potential interactions.
    Annals of the New York Academy of Sciences, 2010, Volume: 1207

    Topics: Aspirin; Cilostazol; Dipyridamole; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Simvastatin; Tetrazoles

2010
Anti-platelet therapy: phosphodiesterase inhibitors.
    British journal of clinical pharmacology, 2011, Volume: 72, Issue:4

    Topics: Blood Platelets; Cilostazol; Clinical Trials as Topic; Dipyridamole; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Thrombosis

2011
Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
    Chest, 2012, Volume: 141, Issue:2 Suppl

    Topics: Aspirin; Cilostazol; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Societies, Medical; Tetrazoles; Thienopyridines; Thrombosis; United States

2012
Targeting phosphodiesterases in anti-platelet therapy.
    Handbook of experimental pharmacology, 2012, Issue:210

    Topics: Animals; Blood Platelets; Cilostazol; Dipyridamole; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Tetrazoles

2012
Antiplatelet therapy for peripheral arterial disease and critical limb ischemia: guidelines abound, but where are the data?
    Journal of cardiovascular pharmacology and therapeutics, 2015, Volume: 20, Issue:2

    Topics: Aspirin; Cilostazol; Dipyridamole; Endovascular Procedures; Extremities; Humans; Ischemia; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prostaglandins; Tetrazoles

2015
Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis.
    BMJ open, 2016, Mar-17, Volume: 6, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Tetrazoles; Ticlopidine

2016
Aspirin plus dipyridamole has the highest surface under the cumulative ranking curves (SUCRA) values in terms of mortality, intracranial hemorrhage, and adverse event rate among 7 drug therapies in the treatment of cerebral infarction.
    Medicine, 2018, Volume: 97, Issue:13

    Topics: Aspirin; Cerebral Infarction; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hematologic Agents; Humans; Intracranial Hemorrhages; Tetrazoles; Ticlopidine; Warfarin

2018
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:5

    Topics: Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Humans; Ischemic Attack, Transient; Ischemic Stroke; Platelet Aggregation Inhibitors; Stroke; Ticagrelor

2022

Trials

2 trial(s) available for cilostazol and dipyridamole

ArticleYear
Platelet activation markers, microparticles and soluble adhesion molecules are elevated in patients with arteriosclerosis obliterans: therapeutic effects by cilostazol and potentiation by dipyridamole.
    Platelets, 2004, Volume: 15, Issue:3

    Topics: Aged; Arteriosclerosis Obliterans; Biomarkers; Case-Control Studies; Cell Adhesion Molecules; Cilostazol; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Particle Size; Platelet Activation; Tetrazoles

2004
Cilostazol and dipyridamole synergistically inhibit human platelet aggregation.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2

    Topics: Adenosine; Animals; Blood Platelets; CHO Cells; Cilostazol; Cricetinae; Cyclic AMP; Dipyridamole; Drug Synergism; Humans; Intracellular Membranes; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Time Factors

2004

Other Studies

14 other study(ies) available for cilostazol and dipyridamole

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
[The mode of action and clinical applications of phosphodiesterase inhibitors as anti-platelet drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cilostazol; Coronary Disease; Coronary Thrombosis; Cyclic AMP; Dipyridamole; Fibrinolytic Agents; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinazolines; Tetrazoles

1989
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines

1999
Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method.
    British journal of pharmacology, 2001, Volume: 133, Issue:8

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Aspirin; Blood Coagulation; Blood Platelets; Cilostazol; Collagen; Dipyridamole; Filtration; Heparin; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Pressure; Tetrazoles; Time Factors; Tirofiban; Tyrosine

2001
Antiplatelet and antithrombotic activity of cilostazol is potentiated by dipyridamole in rabbits and dissociated from bleeding time prolongation.
    Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:1

    Topics: Animals; Bleeding Time; Carotid Artery Thrombosis; Cilostazol; Dipyridamole; Disease Models, Animal; Drug Synergism; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tetrazoles

2005
Synergistic effect of cilostazol and dipyridamole mediated by adenosine on shear-induced platelet aggregation.
    Thrombosis research, 2007, Volume: 119, Issue:4

    Topics: Adenosine; Adult; Cilostazol; Dipyridamole; Drug Synergism; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Shear Strength; Tetrazoles

2007
Medical treatment of patients with intracranial atherosclerotic disease.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2009, Volume: 19 Suppl 1

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Embolism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Intracranial Thrombosis; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Factors; Tetrazoles; Ticlopidine

2009
What is the best first agent to give to a patient with acute ischaemic stroke? Aspirin, heparin, clopidogrel, cilostazol or dipyridamole?
    JPMA. The Journal of the Pakistan Medical Association, 2010, Volume: 60, Issue:10

    Topics: Aspirin; Brain Ischemia; Cilostazol; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Humans; Platelet Aggregation Inhibitors; Stroke; Tetrazoles; Ticlopidine

2010
Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties.
    Journal of the neurological sciences, 2012, Sep-15, Volume: 320, Issue:1-2

    Topics: Actins; Brain; Capillary Permeability; Carbazoles; Cells, Cultured; Cilostazol; Claudin-5; Dipyridamole; Drug Interactions; Electric Impedance; Endothelial Cells; Histamine; Humans; Isoquinolines; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Pyrroles; Rolipram; Sulfonamides; Tetrazoles

2012
Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan.
    Advances in therapy, 2014, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Dipyridamole; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Secondary Prevention; Stroke; Succinates; Tablets, Enteric-Coated; Tetrazoles; Ticlopidine

2014
Cyclic AMP-hydrolyzing phosphodiesterase inhibitors potentiate statin-induced cancer cell death.
    Molecular oncology, 2020, Volume: 14, Issue:10

    Topics: Cell Death; Cell Line, Tumor; Cilostazol; Cyclic AMP; Dipyridamole; Drug Synergism; Humans; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Biological; Neoplasms; Phosphodiesterase Inhibitors; Sterols

2020