cilostamide and 1-methyl-3-isobutylxanthine

cilostamide has been researched along with 1-methyl-3-isobutylxanthine in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (21.21)	18.7374
1990's	7 (21.21)	18.2507
2000's	10 (30.30)	29.6817
2010's	9 (27.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bristol, JA; Cain, MH; Weishaar, RE	1
Hughes, RA; Manallack, DT; Thompson, PE	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Chen, G; Ke, H; Kunz, S; Martinelli, S; Robinson, H; Seebeck, T; Wan, Y; Wang, H	1
Elks, ML; Manganiello, VC	2
Degerman, E; Elks, M; Manganiello, V	1
Malik, KU; Williams, JL	1
Endoh, M; Satoh, K; Yamashita, S	1
Hidaka, H; Manganiello, VC; Osborne, JC; Vaughan, M; Yamamoto, S; Yamamoto, T	1
Moreno, S; Rossi, S; Tomes, C	1
Arauz, E; Fitzpatrick, DF; Krzanowski, JJ; Pan, X; Polson, JB	1
Downing, GJ; Poisner, AM	1
Malik, KU; Schwartz, DD; Williams, JL	1
Poduslo, JF; Walikonis, RS	1
Maurice, DH; Palmer, D; Tsoi, K	1
Conti, M; Hanssen, RG; Hirsch, B; Hsueh, AJ; Kloosterboer, HJ; Tsafriri, A; Van de Kant, M; Wiersma, A	1
Greenberg, AG; Kraemer, FB; Xue, B; Zemel, MB	1
Absher, PM; Dunkerley, HA; Jimmo, SL; Maurice, DH; Netherton, SJ; Palmer, D; Raymond, DR; Russell, JC; Sage, EH; Tilley, DG; Vernon, RB	1
Chung, C; MacNeil, DJ; Morin, NR; Patel, S; Scapin, G; Singh, SB; Tota, MR; Van der Ploeg, LH; Varnerin, JP	1
Maurice, DH; Netherton, SJ	1
Guéguen, L; Laforest, MF; Pouliot, E; Richard, FJ	1
Côté, N; Guillemette, C; Richard, FJ; Sasseville, M	1
Bakavoli, M; Hosseini, A; Mansouri, SM; Nick, RS; Parsaee, H; Saberi, MR; Sadeghian, H; Seyedi, SM	1
Abi-Gerges, A; Conti, M; Fischmeister, R; Heymes, C; Lefebvre, F; Lugnier, C; Mateo, P; Richter, W; Samuel, JL; Vandecasteele, G; Varin, A	1
Albuz, FK; Armstrong, DT; Gilchrist, RB; Lane, M; Sasseville, M; Thompson, JG	1
Gilchrist, RB; Kelly, JM; Rose, RD; Sutton-McDowall, ML; Thompson, JG	1
Das, D; Khan, PP; Maitra, S	1
Dwinell, MB; Hauser, AD; Roy, I; Williams, CL; Wilson, JM; Zimmerman, NP	1
Baulain, U; Diederich, M; Großfeld, R; Heinzmann, J; Herrmann, D; Lucas-Hahn, A; Niemann, H; Timmermann, B; Ulloa, SM	1
de Seigneux, S; Derouette, JP; Dizin, E; Féraille, E; Hasler, U; Martin, PY; Roth, I; Szanto, I	1
Corradini, E; Heck, AJ; Klaasse, G; Leurs, U; Martin, NI; Scholten, A	1
Alam, MH; Lee, J; Miyano, T	1

Reviews

2 review(s) available for cilostamide and 1-methyl-3-isobutylxanthine

Article	Year
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity	1985
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases. Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10 Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines	2005

Article

Year

A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines

2005

Other Studies

31 other study(ies) available for cilostamide and 1-methyl-3-isobutylxanthine

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors. The Journal of biological chemistry, 2012, Apr-06, Volume: 287, Issue:15 Topics: Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Drug Design; Kinetics; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sulfonamides; Surface Properties; Trypanosoma cruzi	2012
A role for soluble cAMP phosphodiesterases in differentiation of 3T3-L1 adipocytes. Journal of cellular physiology, 1985, Volume: 124, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Azo Compounds; Cell Differentiation; Cell Line; Dexamethasone; Glycerolphosphate Dehydrogenase; Insulin; Lipid Metabolism; Mice; Phenylisopropyladenosine; Quinolines; Quinolones; Solubility; Theophylline; Time Factors	1985
Selective inhibitors of specific phosphodiesterases in intact adipocytes. Methods in enzymology, 1988, Volume: 159 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Cattle; Cells, Cultured; Cyclic GMP; Dexamethasone; Insulin; Kinetics; Liver; Mice; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quinolines; Quinolones; Rats; Structure-Activity Relationship	1988
Inhibitory modulation by cAMP of isoproterenol-induced prostacyclin synthesis in rabbit heart. The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclase Inhibitors; Animals; Blood Pressure; Colforsin; Cyclic AMP; Epoprostenol; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Quinolones; Rabbits; Thionucleotides	1989
Inhibition of cyclic AMP phosphodiesterase activity and myocardial contractility: effects of cilostamide, a novel PDE inhibitor, and methylsiobutylxanthine on rabbit and canine ventricular muscle. European journal of pharmacology, 1980, Aug-22, Volume: 66, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Quinolines; Quinolones; Rabbits; Theophylline	1980
Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. The Journal of biological chemistry, 1983, Dec-10, Volume: 258, Issue:23 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cattle; Dipyridamole; Hydrolysis; Kinetics; Liver; Papaverine; Quinolines; Quinolones; Theophylline	1983
Selective effects of phosphodiesterase inhibitors on different phosphodiesterases, adenosine 3',5'-monophosphate metabolism, and lipolysis in 3T3-L1 adipocytes. Endocrinology, 1984, Volume: 115, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Cell Line; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Kinetics; Lipolysis; Mice; Phosphodiesterase Inhibitors; Quinolines; Quinolones	1984
Isobutylmethylxanthine and other classical cyclic nucleotide phosphodiesterase inhibitors affect cAMP-dependent protein kinase activity. Cellular signalling, 1993, Volume: 5, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Etazolate; In Vitro Techniques; Mucor; Myocardium; Phosphodiesterase Inhibitors; Quinolones; Rats; Signal Transduction	1993
Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Cell Line; Drug Synergism; Isoenzymes; Models, Chemical; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyrrolidinones; Quinolones; Rats; Rolipram; Thymidine	1994
Stimulation of placental prorenin secretion by selective inhibition of cyclic nucleotide phosphodiesterases. Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Chorionic Gonadotropin; Culture Media; Culture Techniques; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Precursors; Humans; Placenta; Protein Kinases; Pyridazines; Quinolones; Renin	1995
Contribution of calcium to isoproterenol-stimulated lipolysis in the isolated perfused rabbit heart. The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Diltiazem; Gallic Acid; Glycerol; Heart; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Myocardium; Quinolones; Rabbits	1993
Activity of cyclic AMP phosphodiesterases and adenylyl cyclase in peripheral nerve after crush and permanent transection injuries. The Journal of biological chemistry, 1998, Apr-10, Volume: 273, Issue:15 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene Expression Regulation, Enzymologic; Male; Myelin Sheath; Nerve Crush; Nerve Regeneration; Phosphoric Diester Hydrolases; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Rolipram; S100 Proteins; Sciatic Nerve; Time Factors; Transcription, Genetic; Xanthines	1998
Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors. Circulation research, 1998, May-04, Volume: 82, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Aorta; Becaplermin; Cell Movement; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Synergism; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Quinolones; Rats; Recombinant Proteins	1998
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents. The Journal of clinical investigation, 1998, Aug-01, Volume: 102, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Contraceptive Agents, Female; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Estrus; Female; Fertilization; Heart Rate; Hypoxanthine; Isoenzymes; Meiosis; Menotropins; Mice; Mice, Inbred C57BL; Milrinone; Oogenesis; Ovarian Follicle; Ovulation; Ovulation Induction; Phosphodiesterase Inhibitors; Pregnancy; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Rolipram; Second Messenger Systems; Substrate Specificity; Thiophenes	1998
Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:13 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Androstadienes; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Humans; Insulin; Isoproterenol; Lipolysis; Phosphodiesterase Inhibitors; Phosphorylation; Potassium Chloride; Quinolones; Sterol Esterase; Wortmannin; Xanthines	2001
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease. Diabetes, 2002, Volume: 51, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Cell Membrane; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Diabetes Mellitus, Type 2; Hydrolysis; Muscle, Smooth, Vascular; Obesity; Phenotype; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Mutant Strains	2002
The role of tryptophan 1072 in human PDE3B inhibitor binding. Biochemical and biophysical research communications, 2003, Aug-08, Volume: 307, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; COS Cells; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Escherichia coli; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Phosphodiesterase Inhibitors; Protein Binding; Quinolones; Sequence Alignment; Tryptophan	2003
Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis. Molecular pharmacology, 2005, Volume: 67, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Aorta; Cell Movement; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelium, Vascular; Humans; Kinetics; Microcirculation; Neovascularization, Physiologic; Phosphoric Diester Hydrolases; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Umbilical Veins	2005
Fundamental significance of specific phosphodiesterases in the control of spontaneous meiotic resumption in porcine oocytes. Molecular reproduction and development, 2005, Volume: 70, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Female; Gonadotropins, Equine; Meiosis; Oocytes; Phosphodiesterase Inhibitors; Quinolones; Sus scrofa	2005
New insight into the role of phosphodiesterase 3A in porcine oocyte maturation. BMC developmental biology, 2006, Oct-12, Volume: 6 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cell Nucleus; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Meiosis; Okadaic Acid; Oocytes; Phosphodiesterase Inhibitors; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Time Factors	2006
Design, synthesis and pharmacological evaluation of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives as inotropic agents. Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Amrinone; Animals; Atrial Function; Cardiotonic Agents; Catalytic Domain; Cyclic Nucleotide Phosphodiesterases, Type 3; Drug Design; Molecular Sequence Data; Molecular Structure; Phosphodiesterase Inhibitors; Quinolines; Quinolones; Rats; Rats, Wistar; Sequence Alignment	2009
Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals. Circulation research, 2009, Oct-09, Volume: 105, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aortic Valve Stenosis; Cardiomegaly; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Myocardial Contraction; Myocytes, Cardiac; Organ Size; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Wistar; Second Messenger Systems	2009
Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes. Human reproduction (Oxford, England), 2010, Volume: 25, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Cell Communication; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Culture Media, Serum-Free; Cumulus Cells; Cyclic AMP; Embryo Implantation; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Gap Junctions; Mice; Oocytes; Oogenesis; Pregnancy; Pregnancy Outcome; Quinolones	2010
Regulation of sheep oocyte maturation using cAMP modulators. Theriogenology, 2013, Jan-01, Volume: 79, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Embryo, Mammalian; Embryonic Development; Female; Follicle Stimulating Hormone; In Vitro Oocyte Maturation Techniques; Oocytes; Oogenesis; Osmolar Concentration; Phosphodiesterase Inhibitors; Quality Control; Quinolones; Sheep	2013
Participation of PI3-kinase/Akt signalling in insulin stimulation of p34cdc2 activation in zebrafish oocyte: phosphodiesterase 3 as a potential downstream target. Molecular and cellular endocrinology, 2013, Jul-15, Volume: 374, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Chromones; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Female; Gene Expression Regulation, Developmental; Hydroxyprogesterones; Insulin; Isoenzymes; Meiosis; Morpholines; Oocytes; Phosphatidylinositol 3-Kinase; Phosphodiesterase 3 Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Recombinant Proteins; Signal Transduction; Wortmannin; Zebrafish	2013
Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells. Molecular carcinogenesis, 2015, Volume: 54, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Amides; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Pyridines; Quinolones; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; Vasodilator Agents	2015
Effects of different oocyte retrieval and in vitro maturation systems on bovine embryo development and quality. Zygote (Cambridge, England), 2015, Volume: 23, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Colforsin; Culture Media; DNA Methylation; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; In Vitro Oocyte Maturation Techniques; Male; Oocyte Retrieval; Quinolones	2015
NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity. PloS one, 2014, Volume: 9, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Aquaporin 2; Arginine Vasopressin; Blotting, Western; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Kidney Tubules, Collecting; Mice; NADPH Oxidase 4; NADPH Oxidases; Quinolones; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Rolipram; Signal Transduction	2014
Charting the interactome of PDE3A in human cells using an IBMX based chemical proteomics approach. Molecular bioSystems, 2015, Volume: 11, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; 14-3-3 Proteins; Cyclic Nucleotide Phosphodiesterases, Type 3; HeLa Cells; Humans; Papaverine; Phosphodiesterase Inhibitors; Protein Binding; Protein Interaction Maps; Protein Phosphatase 2; Proteomics; Quinolones	2015
Inhibition of PDE3A sustains meiotic arrest and gap junction of bovine growing oocytes in in vitro growth culture. Theriogenology, 2018, Sep-15, Volume: 118 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Cell Communication; Cell Cycle Checkpoints; Cumulus Cells; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Gap Junctions; In Vitro Oocyte Maturation Techniques; Meiosis; Milrinone; Oocytes; Phosphodiesterase 3 Inhibitors; Quinolones	2018