Compounds > cilomilast
Page last updated: 2024-09-04

cilomilast and pulmicort

cilomilast has been researched along with pulmicort in 5 studies

Compound Research Comparison

Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010)
(cilomilast)		Studies
(pulmicort)		Trials
(pulmicort)		Recent Studies (post-2010) (pulmicort)
16213424,9951,6381,785

Protein Interaction Comparison

ProteinTaxonomycilomilast (IC50)pulmicort (IC50)
Glucocorticoid receptorHomo sapiens (human)0.0026
Progesterone receptorHomo sapiens (human)0.028
Glucocorticoid receptorRattus norvegicus (Norway rat)0.0029
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0045
Mineralocorticoid receptor Homo sapiens (human)0.014
Matrix metalloproteinase-9Homo sapiens (human)1.989
Androgen receptorRattus norvegicus (Norway rat)1.1725
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.0045
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0045
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0045

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Dougall, IG; Ratcliffe, MJ1
Aguiar, JA; Ask, K; Cao, Q; Doxey, AC; Hirota, JA; Hou, V; Huff, RD; Inman, MD; Kim, Y; Miller, MS; Revill, S; Tiessen, N1

Other Studies

5 other study(ies) available for cilomilast and pulmicort

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Comparison of the anti-inflammatory effects of Cilomilast, Budesonide and a p38 Mitogen activated protein kinase inhibitor in COPD lung tissue macrophages.
    BMC pharmacology & toxicology, 2012, Nov-13, Volume: 13

    Topics: Anti-Inflammatory Agents; Budesonide; Cells, Cultured; Cyclohexanecarboxylic Acids; Female; Humans; Interleukin-6; Lipopolysaccharides; Macrophages, Alveolar; Male; Middle Aged; Naphthalenes; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Tumor Necrosis Factor-alpha

2012
Potentiation of long-acting β
    Respiratory research, 2021, Oct-19, Volume: 22, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Benzothiazoles; Budesonide; Cell Line; Chemokines; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Drug Synergism; Drug Therapy, Combination; Epithelial Cells; Formoterol Fumarate; Glucocorticoids; Humans; Lung; Multidrug Resistance-Associated Proteins; Nitriles; Phosphodiesterase 4 Inhibitors; Rolipram; Second Messenger Systems; Triazoles

2021