cilomilast has been researched along with lovastatin in 3 studies
Studies (cilomilast) | Trials (cilomilast) | Recent Studies (post-2010) (cilomilast) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
---|---|---|---|---|---|
162 | 13 | 42 | 4,828 | 698 | 873 |
Protein | Taxonomy | cilomilast (IC50) | lovastatin (IC50) |
---|---|---|---|
Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
Integrin beta-2 | Homo sapiens (human) | 3.09 | |
Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
Neutrophil elastase | Homo sapiens (human) | 0.027 | |
Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
Integrin alpha-L | Homo sapiens (human) | 3.09 | |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
3 other study(ies) available for cilomilast and lovastatin
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |