Page last updated: 2024-09-04

cilomilast and l-791943

cilomilast has been researched along with l-791943 in 3 studies

Compound Research Comparison

Studies (cilomilast)	Trials (cilomilast)	Recent Studies (post-2010) (cilomilast)	Studies (l-791943)	Trials (l-791943)	Recent Studies (post-2010) (l-791943)
162	13	42	5	0	0

Protein Interaction Comparison

Protein	Taxonomy	cilomilast (IC50)	l-791943 (IC50)
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)		0.0042

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blouin, M; Brideau, C; Chan, CC; Chauret, N; Ducharme, Y; Girard, M; Girard, Y; Guay, D; Hamel, P; Huang, Z; Jones, TR; Laliberté, F; Masson, P; McAuliffe, M; Piechuta, H; Silva, J; Young, RN	1
Blouin, M; Brideau, C; Chauret, N; Ducharme, Y; Frenette, R; Friesen, RW; Girard, Y; Hamel, P; Jones, TR; Laliberté, F; Li, C; Masson, P; McAuliffe, M	1
Jabaris, SS; Kodimuthali, A; Pal, M	1

Reviews

1 review(s) available for cilomilast and l-791943

Article	Year
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18 Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive	2008

Other Studies

2 other study(ies) available for cilomilast and l-791943

Article	Year
Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor. Bioorganic & medicinal chemistry letters, 2002, Jun-03, Volume: 12, Issue:11 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Bronchoconstriction; Cell Line, Transformed; Cyclic Nucleotide Phosphodiesterases, Type 4; Emetics; Ferrets; Guinea Pigs; Half-Life; Humans; Inhibitory Concentration 50; Ovalbumin; Phosphodiesterase Inhibitors; Pyridines; Rats; Recombinant Fusion Proteins; Saimiri; Sheep; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2002
Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters. Bioorganic & medicinal chemistry letters, 2002, Oct-21, Volume: 12, Issue:20 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkylation; Animals; Biological Availability; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 4; Half-Life; Humans; Indicators and Reagents; Phosphodiesterase Inhibitors; Pyridines; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2002

Article

Year

Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor.

Bioorganic & medicinal chemistry letters, 2002, Jun-03, Volume: 12, Issue:11

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Bronchoconstriction; Cell Line, Transformed; Cyclic Nucleotide Phosphodiesterases, Type 4; Emetics; Ferrets; Guinea Pigs; Half-Life; Humans; Inhibitory Concentration 50; Ovalbumin; Phosphodiesterase Inhibitors; Pyridines; Rats; Recombinant Fusion Proteins; Saimiri; Sheep; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2002

Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters.

Bioorganic & medicinal chemistry letters, 2002, Oct-21, Volume: 12, Issue:20

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkylation; Animals; Biological Availability; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 4; Half-Life; Humans; Indicators and Reagents; Phosphodiesterase Inhibitors; Pyridines; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2002