Compounds > cilomilast
Page last updated: 2024-09-04

cilomilast and isoproterenol

cilomilast has been researched along with isoproterenol in 4 studies

Compound Research Comparison

Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010)
(cilomilast)		Studies
(isoproterenol)		Trials
(isoproterenol)		Recent Studies (post-2010) (isoproterenol)
162134230,7808032,640

Protein Interaction Comparison

ProteinTaxonomycilomilast (IC50)isoproterenol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.246
Beta-1 adrenergic receptorHomo sapiens (human)0.333
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.77
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.6667

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Huang, L; Jiang, HL; Lai, KF; Li, XS; Luo, ZH; Shan, WJ; Zhou, Q1
Huang, L; Lai, K; Li, X; Shan, W; Xie, J; Zhou, Q1
Darby-King, A; Harley, CW; McLean, JH1

Other Studies

4 other study(ies) available for cilomilast and isoproterenol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD.
    Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Drug Design; Guinea Pigs; Inhibitory Concentration 50; Molecular Structure; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Trachea

2012
Design, synthesis and evaluation of dual pharmacology β2-adrenoceptor agonists and PDE4 inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Design; Ethanolamines; Formoterol Fumarate; Humans; Molecular Structure; Phosphodiesterase 4 Inhibitors; Phthalazines; Receptors, Adrenergic, beta-2; Recombinant Proteins; Structure-Activity Relationship

2014
Potentiation and prolongation of long-term odor memory in neonate rats using a phosphodiesterase inhibitor.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Behavior, Animal; Carboxylic Acids; Conditioning, Classical; Cyclohexanecarboxylic Acids; Discrimination Learning; Drug Interactions; Female; Isoproterenol; Male; Memory; Nitriles; Odorants; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Rolipram; Time Factors

2005