cilomilast has been researched along with interleukin-8 in 8 studies
| Studies (cilomilast) | Trials (cilomilast) | Recent Studies (post-2010) (cilomilast) | Studies (interleukin-8) | Trials (interleukin-8) | Recent Studies (post-2010) (interleukin-8) |
|---|---|---|---|---|---|
| 162 | 13 | 42 | 23,523 | 1,167 | 9,990 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Au, BT; Collins, PD; Teixeira, MM; Williams, TJ | 1 |
| Amit, O; Barnes, NC; Brightling, CE; Compton, C; Edelson, J; Gamble, E; Grootendorst, DC; Hansel, TT; Jeffery, PK; Kroegel, C; Majumdar, S; Matin, D; Morell, F; Parker, D; Pavord, ID; Qiu, Y; Rabe, KF; Rennard, SI; Tat, T; Troy, S; Vignola, AM; Zhu, J | 1 |
| Bellia, V; Bousquet, J; Chiappara, G; Chimenti, L; Costanzo, G; Di Giorgi, R; Mirabella, F; Profita, M; Riccobono, L; Vignola, AM | 1 |
| Cawston, TE; Corris, PA; Fisher, AJ; Forrest, IA; Jones, D; Lordan, JL; Murphy, DM; Pritchard, G; Stovold, R; Ward, C | 1 |
| Aksoy, MO; Ji, R; Kelsen, SG; Li, XX; Reddy, PJ; Yang, Y | 1 |
| Ferraro, M; Giarratano, A; Gjomarkaj, M; Johnson, M; La Grutta, S; Liotta, G; Pace, E; Uasuf, CG | 1 |
| Goto, T; Maeda, H; Nakamura, S; Suzuki, O; Yoshino, T | 1 |
| Ammit, AJ; Baehring, G; Kugel, MJ; Patel, BS | 1 |
1 trial(s) available for cilomilast and interleukin-8
| Article | Year |
|---|---|
Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biopsy; Bronchodilator Agents; Carboxylic Acids; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Interleukin-8; Leukocyte Count; Leukocyte Elastase; Male; Middle Aged; Nitriles; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Sputum; Treatment Outcome | 2003 |
7 other study(ies) available for cilomilast and interleukin-8
| Article | Year |
|---|---|
Effect of PDE4 inhibitors on zymosan-induced IL-8 release from human neutrophils: synergism with prostanoids and salbutamol.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Albuterol; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Drug Synergism; Humans; Interleukin-8; Neutrophils; Nitriles; Phosphodiesterase Inhibitors; Prostaglandins; Pyridines; Pyrrolidinones; Rolipram; Zymosan | 1998 |
Effect of cilomilast (Ariflo) on TNF-alpha, IL-8, and GM-CSF release by airway cells of patients with COPD.
Topics: Adult; Aged; Bronchodilator Agents; Carboxylic Acids; Cell Count; Cells, Cultured; Chemotaxis, Leukocyte; Cyclohexanecarboxylic Acids; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Male; Middle Aged; Nitriles; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Sputum; Tumor Necrosis Factor-alpha | 2003 |
The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bronchi; Carboxylic Acids; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Lung Transplantation; Nitriles; Phosphodiesterase Inhibitors; Vascular Endothelial Growth Factor A | 2006 |
Inhibition by salmeterol and cilomilast of fluticasone-enhanced IP-10 release in airway epithelial cells.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Carboxylic Acids; Cells, Cultured; Chemokine CXCL10; Cyclohexanecarboxylic Acids; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression; Humans; Interleukin-8; Nitriles; Phosphodiesterase Inhibitors; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA; Salmeterol Xinafoate | 2008 |
Cilomilast counteracts the effects of cigarette smoke in airway epithelial cells.
Topics: Cell Line; Chemokine CXCL10; Chemotaxis; Cyclohexanecarboxylic Acids; Gene Expression Regulation; Humans; Interleukin-8; Lymphocytes; Nitriles; Phosphodiesterase 4 Inhibitors; Respiratory Mucosa; Signal Transduction; Smoke; Tobacco Use Disorder; Toll-Like Receptor 4 | 2011 |
The role of phosphodiesterase 4B in IL-8/LTB4-induced human neutrophil chemotaxis evaluated with a phosphodiesterase 4B inhibitor.
Topics: Adult; Aminopyridines; Benzamides; Chemotaxis; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Dose-Response Relationship, Drug; Female; Humans; Interleukin-8; Leukocytes, Mononuclear; Leukotriene B4; Lipopolysaccharides; Male; Neutrophils; Nitriles; Phosphodiesterase 4 Inhibitors; Tumor Necrosis Factor-alpha | 2015 |
Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect.
Topics: Anti-Inflammatory Agents; Bronchi; Bronchodilator Agents; Cells, Cultured; Cyclic AMP; Cyclohexanecarboxylic Acids; Dual Specificity Phosphatase 1; Formoterol Fumarate; Humans; Inflammation; Interleukin-8; Myocytes, Smooth Muscle; Nitriles; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha | 2017 |