Compounds > cilomilast
Page last updated: 2024-09-04

cilomilast and clavulanic acid

cilomilast has been researched along with clavulanic acid in 3 studies

Compound Research Comparison

Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010)
(cilomilast)		Studies
(clavulanic acid)		Trials
(clavulanic acid)		Recent Studies (post-2010) (clavulanic acid)
16213421,801212424

Protein Interaction Comparison

ProteinTaxonomycilomilast (IC50)clavulanic acid (IC50)
Beta-lactamase Klebsiella pneumoniae1.72
Beta-lactamase Escherichia coli0.07
Beta-lactamase Citrobacter gillenii0.009
Beta-lactamase Shouchella clausii0.085
Beta-lactamase Pseudomonas aeruginosa0.1
Beta-lactamase Pseudomonas aeruginosa0.1
Beta-lactamaseStaphylococcus aureus0.08
Beta-lactamaseEscherichia coli K-120.015
Beta-lactamase SHV-1Escherichia coli0.028
Beta-lactamase SHV-1Klebsiella pneumoniae0.17
Beta-lactamase OXA-1Escherichia coli3.2
Cytochrome P450 2B6Homo sapiens (human)0.17
Beta-lactamasePseudomonas aeruginosa PAO10.8
Beta-lactamase TEMEscherichia coli0.0933
Beta-lactamase Salmonella enterica subsp. enterica serovar Westhampton0.01
Beta-lactamase Pseudomonas aeruginosa0.1
Beta-lactamase Klebsiella pneumoniae0.02
Class D beta-lactamaseBrachyspira pilosicoli2
Beta-lactamase Pseudomonas luteola0.036
Beta-lactamase Escherichia coli8.6
Beta-lactamase Escherichia coli0.009

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1

Other Studies

3 other study(ies) available for cilomilast and clavulanic acid

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010