Compounds > cilomilast
Page last updated: 2024-09-04

cilomilast and atropine

cilomilast has been researched along with atropine in 3 studies

Compound Research Comparison

Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010)
(cilomilast)		Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010) (atropine)
162134226,7111,2591,697

Protein Interaction Comparison

ProteinTaxonomycilomilast (IC50)atropine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)21.41
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.012
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0067
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0007
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0009
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0015
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0021
Alpha-1D adrenergic receptorHomo sapiens (human)1.354
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.012

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1

Other Studies

3 other study(ies) available for cilomilast and atropine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010