Compounds > cilengitide
Page last updated: 2024-09-05

cilengitide and tirofiban

cilengitide has been researched along with tirofiban in 5 studies

Compound Research Comparison

Studies
(cilengitide)		Trials
(cilengitide)		Recent Studies (post-2010)
(cilengitide)		Studies
(tirofiban)		Trials
(tirofiban)		Recent Studies (post-2010) (tirofiban)
194291331,210309427

Protein Interaction Comparison

ProteinTaxonomycilengitide (IC50)tirofiban (IC50)
Integrin subunit alpha 2bRattus norvegicus (Norway rat)0.13
Integrin beta-3Homo sapiens (human)0.1184
Integrin alpha-V Homo sapiens (human)0.011
Integrin alpha-IIbHomo sapiens (human)0.1225
Integrin beta-3 Rattus norvegicus (Norway rat)0.13

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Bochen, A; Boehm, H; Di Leva, FS; Kessler, H; Marelli, UK; Marinelli, L; Mas-Moruno, C; Novellino, E; Otto, E; Pallarola, D; Spatz, JP1
De Simone, M; Di Leva, FS; Hegemann, JD; Kessler, H; Knappe, TA; Marahiel, MA; Marinelli, L; Novellino, E; Xie, X; Zahler, S; Zimmermann, M1
Kemker, I; Marion, A; Schnepel, C; Schröder, DC; Sewald, N1
Dangi, A; Marelli, UK; Meena, CL; Reichart, F; Sanjayan, GJ; Singh, D; Weinmüller, M; Zahler, S1
Feiner, RC; Kemker, I; Marion, A; Müller, KM; Schröder, DC; Sewald, N1

Other Studies

5 other study(ies) available for cilengitide and tirofiban

ArticleYear
Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids.
    Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4

    Topics: Amino Acids; Animals; Antigens, Neoplasm; Cell Adhesion; Cell Line; Fibrinogen; Fibronectins; Gold; Integrin alpha5beta1; Integrins; Latent TGF-beta Binding Proteins; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Nanoparticles; Oligopeptides; Peptides, Cyclic; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Vitronectin

2013
Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
    Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13

    Topics: Bacteriocins; Cell Adhesion; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Models, Molecular; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Snake Venoms

2014
Cyclization of RGD Peptides by Suzuki-Miyaura Cross-Coupling.
    Journal of medicinal chemistry, 2019, 08-22, Volume: 62, Issue:16

    Topics: Boronic Acids; Cell Line, Tumor; Cyclization; Humans; Hydrocarbons, Halogenated; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Oligopeptides; Solvents; Structure-Activity Relationship

2019
Novel cilengitide-based cyclic RGD peptides as αvβ
    Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8

    Topics: Dose-Response Relationship, Drug; Humans; Integrin alphaVbeta3; Molecular Structure; Peptides, Cyclic; Structure-Activity Relationship

2020
Tuning the Biological Activity of RGD Peptides with Halotryptophans†.
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Chromatography, High Pressure Liquid; Feasibility Studies; Halogens; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Oligopeptides; Structure-Activity Relationship; Tryptophan

2021