Page last updated: 2024-09-05

cilengitide and cyclic(arg-gly-asp-d-phe-val)

cilengitide has been researched along with cyclic(arg-gly-asp-d-phe-val) in 5 studies

Compound Research Comparison

Studies
(cilengitide)
Trials
(cilengitide)
Recent Studies (post-2010)
(cilengitide)
Studies
(cyclic(arg-gly-asp-d-phe-val))
Trials
(cyclic(arg-gly-asp-d-phe-val))
Recent Studies (post-2010) (cyclic(arg-gly-asp-d-phe-val))
194291332009

Protein Interaction Comparison

ProteinTaxonomycilengitide (IC50)cyclic(arg-gly-asp-d-phe-val) (IC50)
Integrin beta-3Homo sapiens (human)1.239
Integrin alpha-V Homo sapiens (human)1.0243
Integrin beta-5Homo sapiens (human)0.0063
Integrin beta-6Homo sapiens (human)3.696

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auzzas, L; Battistini, L; Belvisi, L; Burreddu, P; Casiraghi, G; Castorina, M; Curti, C; Gaetani, E; Giannini, G; Motto, I; Nicastro, G; Pisano, C; Rassu, G; Zanardi, F1
Castorina, M; Dal Pozzo, A; de Castiglione, R; Giannini, G; Mazzini, S; Mondelli, R; Muzi, L; Ni, M; Penco, S; Pisano, C1
Bottoncetti, A; Brandi, A; Cini, N; Cordero, FM; Gratteri, P; Melani, F; Pisaneschi, F; Salvati, M1
Corti, A; Curnis, F; Ghitti, M; Gori, A; Musco, G; Nardelli, F; Paissoni, C; Quilici, G; Sacchi, A; Traversari, C; Valentinis, B1
Kemker, I; Marion, A; Schnepel, C; Schröder, DC; Sewald, N1

Other Studies

5 other study(ies) available for cilengitide and cyclic(arg-gly-asp-d-phe-val)

ArticleYear
Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.
    Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24

    Topics: Binding, Competitive; Crystallography, X-Ray; Cycloleucine; Integrin alphaVbeta3; Integrins; Models, Molecular; Molecular Structure; Oligopeptides; Peptides, Cyclic; Protein Binding; Radioligand Assay; Receptors, Vitronectin; Snake Venoms; Solutions; Structure-Activity Relationship

2005
Incorporation of the unusual C(alpha)-fluoroalkylamino acids into cyclopeptides: synthesis of arginine-glycine-aspartate (RGD) analogues and study of their conformational and biological behavior.
    Journal of medicinal chemistry, 2006, Mar-09, Volume: 49, Issue:5

    Topics: Amino Acids; Dimethyl Sulfoxide; Fluorine; Integrin alphaVbeta3; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Receptors, Vitronectin; Stereoisomerism; Structure-Activity Relationship; Water

2006
Synthesis, SAR and in vitro evaluation of new cyclic Arg-Gly-Asp pseudopentapeptides containing a s-cis peptide bond as integrin alphavbeta3 and alphavbeta5 ligands.
    Bioorganic & medicinal chemistry, 2008, Apr-15, Volume: 16, Issue:8

    Topics: Computer Simulation; Integrin alphaVbeta3; Integrins; Ligands; Models, Molecular; Molecular Structure; Oligopeptides; Peptides, Cyclic; Receptors, Vitronectin; Structure-Activity Relationship

2008
Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to α
    Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17

    Topics: Allosteric Regulation; Binding, Competitive; Cell Line, Tumor; Cell Membrane; HEK293 Cells; Humans; Integrin alphaVbeta3; Magnetic Resonance Spectroscopy; Melanoma; Molecular Docking Simulation; Peptides, Cyclic; Protein Conformation; Snake Venoms; Structure-Activity Relationship; Succinimides; Tyrosine

2018
Cyclization of RGD Peptides by Suzuki-Miyaura Cross-Coupling.
    Journal of medicinal chemistry, 2019, 08-22, Volume: 62, Issue:16

    Topics: Boronic Acids; Cell Line, Tumor; Cyclization; Humans; Hydrocarbons, Halogenated; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Oligopeptides; Solvents; Structure-Activity Relationship

2019