cilengitide has been researched along with cgp 77675 in 1 studies
| Studies (cilengitide) | Trials (cilengitide) | Recent Studies (post-2010) (cilengitide) | Studies (cgp 77675) | Trials (cgp 77675) | Recent Studies (post-2010) (cgp 77675) |
|---|---|---|---|---|---|
| 194 | 29 | 133 | 20 | 0 | 5 |
| Protein | Taxonomy | cilengitide (IC50) | cgp 77675 (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 0.0004 | |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | 0.0004 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 0.0102 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alghisi, GC; Ponsonnet, L; Rüegg, C | 1 |
1 other study(ies) available for cilengitide and cgp 77675
| Article | Year |
|---|---|
The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.
Topics: Animals; Antigens, CD; Cadherins; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alphaVbeta3; Integrin beta1; Intercellular Junctions; Permeability; Phosphorylation; Pyrimidines; Pyrroles; Snake Venoms; src-Family Kinases | 2009 |