Page last updated: 2024-09-05

cilengitide and arginyl-glycyl-aspartic acid

cilengitide has been researched along with arginyl-glycyl-aspartic acid in 11 studies

Compound Research Comparison

Studies
(cilengitide)
Trials
(cilengitide)
Recent Studies (post-2010)
(cilengitide)
Studies
(arginyl-glycyl-aspartic acid)
Trials
(arginyl-glycyl-aspartic acid)
Recent Studies (post-2010) (arginyl-glycyl-aspartic acid)
194291334,556171,799

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Simone, M; Di Leva, FS; Hegemann, JD; Kessler, H; Knappe, TA; Marahiel, MA; Marinelli, L; Novellino, E; Xie, X; Zahler, S; Zimmermann, M1
Arnaout, MA; Frech, M; Goodman, SL; Joachimiak, A; Stehle, T; Xiong, JP; Zhang, R1
Achilefu, S; Bloch, S; Chance, B; Dorshow, RB; Liang, K; Markiewicz, MA; Ye, Y; Zhong, T1
Auzzas, L; Battistini, L; Belvisi, L; Burreddu, P; Casiraghi, G; Castorina, M; Curti, C; Gaetani, E; Giannini, G; Motto, I; Nicastro, G; Pisano, C; Rassu, G; Zanardi, F1
Jiang, FC; Ni, GH1
Cai, W; Chen, X1
Mikkelsen, T; Nabors, LB; Reardon, DA; Stupp, R1
Nabors, LB; Neyns, B; Reardon, DA; Stupp, R; Tonn, JC; Weller, M1
Joner, M; Kapp, TG; Kessler, H; Laufer, B; Li, L; Mas-Moruno, C; Neubauer, S; Rechenmacher, F; Steigerwald, K1
Byron, SK; Craig, SE; Humphries, MJ; Jowitt, TA; Mould, AP1
An, X; Ge, H; Gu, T; Guo, L; Jiang, Q; Meng, X; Ning, X; Shan, X; Zhang, L1

Reviews

3 review(s) available for cilengitide and arginyl-glycyl-aspartic acid

ArticleYear
[Advances in the study of the integrin alpha(v) beta3 antagonists].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:7

    Topics: Acetates; Aminopyridines; Angiogenesis Inhibitors; Benzodiazepinones; Humans; Integrin alphaVbeta3; Ligands; Molecular Structure; Oligopeptides; Peptides, Cyclic; Snake Venoms

2006
Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism.
    Anti-cancer agents in medicinal chemistry, 2006, Volume: 6, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disintegrins; Drug Delivery Systems; Gene Silencing; Gene Targeting; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Neoplasms; Oligopeptides; Positron-Emission Tomography; RNA, Small Interfering; Snake Venoms; Tomography, Emission-Computed, Single-Photon; Ultrasonography

2006
Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme.
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Central Nervous System Neoplasms; Clinical Trials as Topic; Drug Evaluation, Preclinical; Glioblastoma; Humans; Integrins; Models, Molecular; Oligopeptides; Protein Binding; Snake Venoms; Treatment Outcome

2008

Other Studies

8 other study(ies) available for cilengitide and arginyl-glycyl-aspartic acid

ArticleYear
Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
    Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13

    Topics: Bacteriocins; Cell Adhesion; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Models, Molecular; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Snake Venoms

2014
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.
    Science (New York, N.Y.), 2002, Apr-05, Volume: 296, Issue:5565

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Ligands; Manganese; Models, Molecular; Oligopeptides; Peptides, Cyclic; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Vitronectin; Snake Venoms

2002
Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, May-31, Volume: 102, Issue:22

    Topics: Animals; Carbocyanines; Fluorometry; Integrins; Ligands; Mice; Mice, Nude; Microscopy, Fluorescence; Molecular Probe Techniques; Neoplasms; Oligopeptides; Peptides, Cyclic; Snake Venoms; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2005
Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.
    Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24

    Topics: Binding, Competitive; Crystallography, X-Ray; Cycloleucine; Integrin alphaVbeta3; Integrins; Models, Molecular; Molecular Structure; Oligopeptides; Peptides, Cyclic; Protein Binding; Radioligand Assay; Receptors, Vitronectin; Snake Venoms; Solutions; Structure-Activity Relationship

2005
Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies.
    Future oncology (London, England), 2011, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Industry; Glioblastoma; Humans; Integrins; Oligopeptides; Snake Venoms; Treatment Outcome

2011
The integrin ligand c(RGDf(NMe)Nal) reduces neointimal hyperplasia in a polymer-free drug-eluting stent system.
    ChemMedChem, 2014, Volume: 9, Issue:7

    Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drug-Eluting Stents; Hyperplasia; Immunosuppressive Agents; Integrins; Oligopeptides; Polymers; Rabbits; Snake Venoms; Wound Healing

2014
Disruption of integrin-fibronectin complexes by allosteric but not ligand-mimetic inhibitors.
    The Biochemical journal, 2014, Dec-15, Volume: 464, Issue:3

    Topics: Allosteric Site; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Binding Sites; Cells, Cultured; Fibronectins; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Integrins; Ligands; Multiprotein Complexes; Oligopeptides; Peptide Fragments; Protein Binding; Receptors, Vitronectin; Sf9 Cells; Snake Venoms; Spodoptera

2014
Novel Integrin αvβ3-Specific Ligand for the Sensitive Diagnosis of Glioblastoma.
    Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Gene Knockout Techniques; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Ligands; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Optical Imaging; Protein Binding; Snake Venoms; Transfection; Xenograft Model Antitumor Assays

2019