cilazaprilat has been researched along with cilazapril, anhydrous in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (28.95) | 18.7374 |
| 1990's | 20 (52.63) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 1 (2.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
| Brown, AN; Dymond, DS; Elstob, JE; Francis, RJ; Rajaguru, S; Steiner, J; Wiseman, MN | 1 |
| Andersson, RG; Karlberg, BE; Lindgren, BR; Persson, K; Rosenqvist, U | 1 |
| Andersson, RG; Persson, KM | 1 |
| Andersson, RG; Lindgren, BR; Persson, K; Rosenqvist, U | 1 |
| Mombouli, JV; Nephtali, M; Vanhoutte, PM | 1 |
| Lijnen, P | 1 |
| Baumgartner, HR; Clozel, JP; Hefti, F; Hosang, M; Kuhn, H; Müller, RK; Powell, JS | 1 |
| Brown, A; DeFeo, T; Limjuco, R; Lin, A; Massarella, J | 1 |
| Brown, AN; DeFeo, TM; Lin, A; Massarella, JW; Wills, RJ | 1 |
| Brown, AN; Durnin, C; McEwen, J; Rajaguru, S; Walters, GE; Williams, PE | 1 |
| Doorenbos, CJ; van Brummelen, P | 1 |
| Brown, AN; Fillastre, JP; Francis, RJ; Godin, M; Manfredi, R; Moulin, B; Pinta, P; Williams, PE | 1 |
| Elliott, HL; Francis, RJ; Meredith, PA; Reid, JL | 1 |
| Johnston, GD; Walters, GE; Whitehead, EM; Williams, PE | 1 |
| Ohta, Y; Sugawara, M; Tanaka, H; Umeda, I; Yoneyama, Y | 1 |
| Cubela, R; Jackson, B; Johnston, CI | 1 |
| Chiba, K; Matsuoka, T; Satoh, S; Suzuki-Kusaba, M | 1 |
| Ikeda, U; Shimada, K | 1 |
| Lloyd, GS; Turner, AJ | 1 |
| Bühler, FR; Hahn, AW; Kern, F; Resink, TJ; Schmidt, R | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Kosaka, H; Minamino, T; Mori, H; Node, K; Shinozaki, Y | 1 |
| Gross, V; Haag, K; Neis, W; Schölmerich, J; Treher, E; Wiegand, U | 1 |
| Becker, BF; Gerlach, E; Kupatt, C; Möbert, J; Zahler, S | 1 |
| Andersson, RG; Persson, K | 1 |
| Becker, BF; Gerlach, E; Habazettl, H; Kupatt, C; Messmer, K; Weber, C; Zahler, S | 1 |
| Hori, M; Kitakaze, M; Kosaka, H; Minamino, T; Mori, H; Node, K | 1 |
| Alonso, RM; Jiménez, RM; Prieto, JA | 1 |
| Asanuma, H; Hori, M; Kitakaze, M; Kosaka, H; Kuzuya, T; Minamino, T; Node, K; Ueda, Y | 1 |
| Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T | 1 |
| Arakawa, K; Hayashi, K; Honda, M; Kajiya, F; Kubota, E; Matsuda, H; Matsumoto, A; Naitoh, M; Saruta, T; Suzuki, H; Yamamoto, T | 1 |
| Becker, BF; Kupatt, C; Zahler, S | 1 |
| Alonso, RM; Jiménez, RM; Ortiz, E; Prieto, JA | 1 |
| Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Okubo, K; Ozawa, Y; Saruta, T; Takamatsu, I; Tatematsu, S; Tokuyama, H; Wakino, S | 1 |
| Arakawa, K; Goto, M; Hayashi, K; Hiramatsu, O; Kajiya, F; Matsuda, H; Nakamoto, H; Ogasawara, Y; Suzuki, H; Tachibana, H; Toyota, E; Yada, T | 1 |
| Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Saruta, T; Takamatsu, I; Tatematsu, S; Tokuyama, H; Wakino, S | 1 |
| Aleksandrowicz, E; Larczyński, W; Lysiak-Szydlowska, W; Renke, M; Rutkowski, B; Rutkowski, P; Tylicki, L | 1 |
| Narayanam, M; Sahu, A; Singh, S | 1 |
6 trial(s) available for cilazaprilat and cilazapril, anhydrous
| Article | Year |
|---|---|
The pharmacokinetics and dose proportionality of cilazapril.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Humans; Middle Aged; Pyridazines | 1989 |
The influence of food on the pharmacokinetics and ACE inhibition of cilazapril.
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Cilazapril; Food; Humans; Pyridazines | 1989 |
The effect of acute ACE inhibition on atrial natriuretic peptide.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Cilazapril; Heart Rate; Humans; Infusions, Intravenous; Male; Pyridazines; Renin; Renin-Angiotensin System; Sodium | 1989 |
The pharmacokinetics and angiotensin converting enzyme inhibition dynamics of cilazapril in essential hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Models, Biological; Peptidyl-Dipeptidase A; Pyridazines | 1989 |
Pharmacokinetics of intravenous cilazaprilat in normal volunteers.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Hemodynamics; Humans; Infusions, Intravenous; Male; Pyridazines; Regional Blood Flow | 1989 |
Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Chronic Disease; Cilazapril; Collagen Type III; Cross-Over Studies; Disease Progression; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Potassium; Proteinuria; Renin-Angiotensin System; Spironolactone; Telmisartan | 2008 |
32 other study(ies) available for cilazaprilat and cilazapril, anhydrous
| Article | Year |
|---|---|
Interaction of digoxin with antihypertensive drugs via MDR1.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors | 2002 |
Initial and steady state pharmacokinetics of cilazapril in congestive cardiac failure.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Female; Heart Failure; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Pyridazines | 1991 |
Enalaprilat, but not cilazaprilat, increases inflammatory skin reactions in guinea-pigs.
Topics: Allergens; Angiotensin-Converting Enzyme Inhibitors; Animals; Cilazapril; Dermatitis, Contact; Enalaprilat; Female; Guinea Pigs; Histamine; Peptidyl-Dipeptidase A; Pyridazines; Skin; Substance P | 1991 |
Enalaprilat versus cilazaprilat: a comparison of allergic skin reactions in the guinea pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens; Cilazapril; Dermatitis; Enalaprilat; Female; Guinea Pigs; Histamine Release; Hypersensitivity; Ovalbumin; Pyridazines | 1991 |
Effects of cilazaprilat and enalaprilat on experimental dermatitis in guinea pigs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Dermatitis; Drug Synergism; Enalaprilat; Erythema; Female; Guinea Pigs; Inflammation; Ovalbumin; Pyridazines; Substance P | 1991 |
Effects of the converting enzyme inhibitor cilazaprilat on endothelium-dependent responses.
Topics: Acetylcholine; Adenosine Diphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; Pyridazines; Vasoconstriction; Vasodilation | 1991 |
In vitro effect of cilazaprilat on sodium-potassium transport systems in human erythrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Angiotensin-Converting Enzyme Inhibitors; Biological Transport; Cilazapril; Erythrocytes; Humans; In Vitro Techniques; Lithium; Male; Potassium; Pyridazines; Rubidium Radioisotopes; Sodium | 1990 |
Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Catheterization; Cell Division; Cilazapril; Male; Muscle, Smooth, Vascular; Pyridazines; Rats | 1989 |
A pharmacokinetic study of cilazapril in elderly and young volunteers.
Topics: Administration, Oral; Adolescent; Aged; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Child; Cilazapril; Creatinine; Female; Half-Life; Humans; Male; Pyridazines | 1989 |
Pharmacokinetics of cilazapril in patients with renal failure.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Creatinine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyridazines; Renal Dialysis | 1989 |
Enzyme immunoassay discrimination of a new angiotensin-converting enzyme (ACE) inhibitor, cilazapril, and its active metabolite.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Callitrichinae; Cilazapril; Humans; Immunoenzyme Techniques; Pyridazines | 1987 |
Measurement of angiotensin converting enzyme inhibitors in serum by radioinhibitor binding displacement assay.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cilazapril; Dipeptides; Enalapril; Female; Iodine Radioisotopes; Lisinopril; Peptidyl-Dipeptidase A; Pyridazines; Rats; Rats, Inbred Strains | 1987 |
Inhibitory effect of cilazaprilat on norepinephrine release induced by renal nerve stimulation in anesthetized dogs.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Cilazapril; Dogs; Electric Stimulation; Female; Kidney; Male; Norepinephrine; Pyridazines | 1988 |
Nitric oxide release from rat aortic smooth muscle cells is not attenuated by angiotensin converting enzyme inhibitors.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Captopril; Cells, Cultured; Cilazapril; Enalaprilat; Enzyme Induction; Humans; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Transcription, Genetic | 1994 |
Aminopeptidase P: cation activation and inhibitor sensitivity are substrate-dependent.
Topics: Amino Acid Sequence; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Enalaprilat; Kidney; Kinetics; Molecular Sequence Data; Oligopeptides; Ramipril; Substance P; Substrate Specificity; Swine | 1995 |
Endothelium-modulated proliferation of medial smooth muscle cells: influence of angiotensin II and converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Carotid Arteries; Catheterization; Cell Division; Cilazapril; Endothelium, Vascular; Muscle, Smooth, Vascular; Organoids; Rats; Thymidine | 1995 |
Beneficial effects of inhibition of angiotensin-converting enzyme on ischemic myocardium during coronary hypoperfusion in dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Coronary Circulation; Dogs; Myocardial Ischemia; Nitric Oxide | 1995 |
Angiotensin-converting enzyme (ACE)-inhibition in cirrhosis. Pharmacokinetics and dynamics of the ACE-inhibitor cilazapril (Ro 31-2848).
Topics: Adult; Alanine Transaminase; Angiotensin-Converting Enzyme Inhibitors; Aspartate Aminotransferases; Bilirubin; Blood Pressure; Cholinesterases; Cilazapril; Creatinine; Female; Galactose; Heart Rate; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Reference Values; Renin; Serum Albumin | 1993 |
Effects of ACE-inhibition on redox status and expression of P-selectin of endothelial cells subjected to oxidative stress.
Topics: Angiotensin-Converting Enzyme Inhibitors; Cell Adhesion; Cells, Cultured; Cilazapril; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Humans; Neutrophils; Oxidation-Reduction; Oxidative Stress; P-Selectin | 1997 |
Biphasic response to bradykinin in isolated porcine iliac arteries is mediated by bradykinin B1 and B2 receptors.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cilazapril; Cycloheximide; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Protease Inhibitors; Protein Synthesis Inhibitors; Receptors, Bradykinin; Swine; Vasoconstriction; Vasodilation | 1998 |
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Adhesion; Cilazapril; Coronary Vessels; Flow Cytometry; Guinea Pigs; Macrophage-1 Antigen; Male; Microscopy, Fluorescence; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion | 1997 |
Role of Ca2+-activated K+ channels in the protective effect of ACE inhibition against ischemic myocardial injury.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcium; Cilazapril; Collateral Circulation; Coronary Circulation; Data Interpretation, Statistical; Dogs; Enzyme Inhibitors; Epoprostenol; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channels; Scorpion Venoms; Time Factors; Toxins, Biological | 1998 |
Quantitative determination of the angiotensin-converting enzyme inhibitor cilazapril and its active metabolite cilazaprilat in pharmaceuticals and urine by high-performance liquid chromatography with amperometric detection.
Topics: Angiotensin-Converting Enzyme Inhibitors; Chromatography, High Pressure Liquid; Cilazapril; Electrochemistry; Humans; Tablets | 1998 |
Inhibition of angiotensin-converting enzyme increases the nitric oxide levels in canine ischemic myocardium.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Coronary Circulation; Dogs; Imidazoles; Imidazolidines; Myocardial Ischemia; Nitric Oxide; Peptidyl-Dipeptidase A | 1998 |
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles | 1999 |
Zonal heterogeneity in action of angiotensin-converting enzyme inhibitor on renal microcirculation: role of intrarenal bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Dogs; Imidazoles; Male; Microcirculation; Nitric Oxide; Pyridines; Receptors, Angiotensin; Renal Circulation; Vasodilation | 1999 |
ACE-inhibition attenuates cardiac cell damage and preserves release of NO in the postischemic heart.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cilazapril; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide | 1999 |
Determination of the antihypertensive drug cilazapril and its active metabolite cilazaprilat in pharmaceuticals and urine by solid-phase extraction and high-performance liquid chromatography with photometric detection.
Topics: Antihypertensive Agents; Chromatography, High Pressure Liquid; Cilazapril; Electrochemistry; Humans; Hypertension; Molecular Structure; Photometry | 2001 |
Differential regulation of elevated renal angiotensin II in chronic renal ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Chronic Disease; Chymases; Cilazapril; Dogs; Hemodynamics; Hypertension, Renal; Imidazoles; Ischemia; Kidney; Male; Oligopeptides; Olmesartan Medoxomil; Peptidyl-Dipeptidase A; Renal Circulation; Renin-Angiotensin System; Serine Endopeptidases; Tetrazoles | 2002 |
In vivo visualization of subendocardial arteriolar response in renovascular hypertensive hearts.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Cilazapril; Coronary Vessels; Dogs; Endocardium; Endothelium, Vascular; Female; Hypertension, Renal; Male; Microscopy; Papaverine; Vasodilation; Vasodilator Agents | 2003 |
Role of endothelium-derived hyperpolarizing factor in ACE inhibitor-induced renal vasodilation in vivo.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Factors; Bradykinin; Cilazapril; Dogs; Kidney; Male; Microcirculation; Nitric Oxide; Renal Circulation; Vasodilation | 2004 |
Use of LC-MS/TOF, LC-MS(n), NMR and LC-NMR in characterization of stress degradation products: Application to cilazapril.
Topics: Chromatography, High Pressure Liquid; Cilazapril; Drug Stability; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction | 2015 |