ciglitazone has been researched along with pd 98059 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Dixon, C; Hilbelink, T; Lu, L; Rovin, BH; Wilmer, WA | 1 |
| Blaschke, F; Bungenstock, A; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Stawowy, P | 1 |
| Bungenstock, A; Czupalla, C; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Nürnberg, B; Spencer-Hänsch, C; Stawowy, P | 1 |
| Fakhry, I; Gehr, TW; Ghosh, S; Ghosh, SS; Lyall, V; Schoolwerth, AC; Sica, DA | 1 |
| Dai, J; Remick, DG; Wang, X; Zeng, X | 1 |
| Kim, HK; Kim, HS; Kim, HY; Kim, JR | 1 |
| Chen, F; Harrison, LE; Kim, E; Wang, CC | 1 |
8 other study(ies) available for ciglitazone and pd 98059
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glomerular Mesangium; Humans; Hypoglycemic Agents; Immunologic Factors; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
PPAR activators inhibit endothelial cell migration by targeting Akt.
Topics: Apoptosis; Blotting, Western; Cell Movement; Cells, Cultured; Chromans; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fenofibrate; Flavonoids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; In Situ Nick-End Labeling; Lipid Metabolism; Lymphokines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peroxisome Proliferators; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2002 |
Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands.
Topics: Androstadienes; Cell Line; Cell Movement; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins; Wortmannin | 2002 |
PPARgamma ligand attenuates PDGF-induced mesangial cell proliferation: role of MAP kinase.
Topics: Animals; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Drug Synergism; Enzyme Inhibitors; Flavonoids; Gene Expression; Gene Expression Regulation; Genes, fos; Glomerular Mesangium; Ligands; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Receptors, Cytoplasmic and Nuclear; Serum Response Element; Thiazolidinediones; Transcription Factors; Tumor Suppressor Proteins | 2003 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins | 2003 |
Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages.
Topics: Animals; Blotting, Northern; Chemokine CXCL1; Chemokines, CXC; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Flavonoids; Gene Expression; Hypoglycemic Agents; Immunologic Factors; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; PPAR gamma; Prostaglandin D2; Pyrrolidines; RNA Stability; RNA, Messenger; Specific Pathogen-Free Organisms; Thiazolidinediones; Thiocarbamates; Time Factors; Up-Regulation | 2005 |
Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway.
Topics: Binding Sites; Butadienes; Cyclin-Dependent Kinase Inhibitor p27; Flavonoids; Gene Expression Regulation; HT29 Cells; Humans; Luciferases; MAP Kinase Signaling System; Nitriles; Phosphorylation; Plicamycin; Promoter Regions, Genetic; Sp1 Transcription Factor; Thiazolidinediones; Time Factors; Transcription, Genetic; Transfection | 2005 |