Compounds > ciglitazone

ciglitazone and clofibrate

ciglitazone has been researched along with clofibrate in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.67)	18.7374
1990's	1 (6.67)	18.2507
2000's	8 (53.33)	29.6817
2010's	5 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aizawa, Y; Fujita, T; Hasegawa, K; Horikoshi, H; Kanai, T; Kurumada, T; Yoshioka, T	1
Blanchard, SG; Brackeen, MF; Brown, KK; Cobb, JE; Collins, JL; Harrington, WW; Hashim, MA; Henke, BR; Hull-Ryde, EA; Kaldor, I; Kliewer, SA; Lake, DH; Leesnitzer, LM; Lehmann, JM; Lenhard, JM; Miller, JF; Mook, RA; Noble, SA; Oliver, W; Orband-Miller, LA; Parks, DJ; Plunket, KD; Szewczyk, JR; Willson, TM	1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Baik, EJ; Kim, EJ; Kwon, KJ; Lee, SH; Moon, CH; Park, JY	1
Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS	1
Fujita, T; Ikeda, H; Kawamatsu, Y; Meguro, K; Sohda, T	1
Beauregard, C; Brandt, PC	1
Newaz, M; Oyekan, A; Yousefipour, Z	1
Catalán, J; Giral, H; Sorribas, V; Villa-Bellosta, R	1
Chang, S; Choi, EH; Demerjian, M; Elias, PM; Feingold, KR; Man, MQ	1
Crowe, DL; Han, JS	1

Reviews

1 review(s) available for ciglitazone and clofibrate

Article	Year
[Discovery and development of a new insulin sensitizing agent, pioglitazone]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:11 Topics: Animals; Clinical Trials as Topic; Clofibrate; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drug Design; Humans; Hypoglycemic Agents; Insulin Resistance; Mice; Pioglitazone; Thiazoles; Thiazolidinediones	2002

Other Studies

14 other study(ies) available for ciglitazone and clofibrate

Article	Year
Studies on hindered phenols and analogues. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation. Journal of medicinal chemistry, 1989, Volume: 32, Issue:2 Topics: Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Rats; Structure-Activity Relationship	1989
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents. Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25 Topics: Administration, Oral; Aminopyridines; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Lipids; Male; Mice; Oxazoles; Propionates; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Transfection; Tyrosine	1998
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. Brain research, 2002, Jun-21, Volume: 941, Issue:1-2 Topics: Animals; Cell Culture Techniques; Cell Death; Chromans; Clofibrate; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Escherichia coli; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lipopolysaccharides; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisome Proliferators; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2002
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:9 Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	2002
Peroxisome proliferator-activated receptor agonists inhibit interleukin-1beta-mediated nitric oxide production in cultured lacrimal gland acinar cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:6 Topics: Animals; Cell Line, Transformed; Chromans; Clofibrate; Dexamethasone; Gene Expression; Humans; Interleukin-1; Lacrimal Apparatus; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; PPAR alpha; PPAR gamma; Pterins; Pyrimidines; Rabbits; Thiazolidinediones; Troglitazone	2003
Role of PPAR-gamma on the pathogenesis and vascular changes in glycerol-induced acute renal failure. Pharmacological research, 2006, Volume: 54, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Angiotensin II; Animals; Ascorbic Acid; Clofibrate; Down-Regulation; Free Radicals; Glycerol; Kidney; Male; Nitric Oxide; Nitriles; PPAR gamma; Rats; Rats, Sprague-Dawley; Renal Circulation; Thiazolidinediones; Thromboxane A2; Vasoconstriction	2006
Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines. Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:6 Topics: Animals; Caspase 3; Cell Line; Cell Survival; Clofibrate; DNA Fragmentation; Hypoglycemic Agents; Hypolipidemic Agents; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; LLC-PK1 Cells; Mice; Opossums; Peroxisome Proliferators; Pioglitazone; PPAR alpha; PPAR gamma; Pyrimidines; Swine; Thiazolidinediones	2007
Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis. Experimental dermatology, 2009, Volume: 18, Issue:7 Topics: Animals; Cell Differentiation; Cell Membrane Permeability; Cell Proliferation; Clobetasol; Clofibrate; DNA-Binding Proteins; Epidermis; Female; Glucocorticoids; Hydroxycholesterols; Keratinocytes; Liver X Receptors; Male; Mice; Mice, Hairless; Models, Animal; Orphan Nuclear Receptors; PPAR alpha; PPAR gamma; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones	2009
Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands. BMC cancer, 2010, Nov-16, Volume: 10 Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chromatin Assembly and Disassembly; Clofibrate; CREB-Binding Protein; Fatty Acids, Unsaturated; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Invasiveness; Nuclear Receptor Coactivator 1; Peroxisome Proliferator-Activated Receptors; Promoter Regions, Genetic; Retinoid X Receptors; Tetrahydronaphthalenes; Thiazolidinediones; Time Factors; Transfection; Tumor Burden	2010