Page last updated: 2024-08-24

cidofovir anhydrous and probenecid

cidofovir anhydrous has been researched along with probenecid in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (36.11)	18.2507
2000's	14 (38.89)	29.6817
2010's	8 (22.22)	24.3611
2020's	1 (2.78)	2.80

Authors

Authors	Studies
Cihlar, T; Ho, ES	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Cundy, KC; Fisher, PE; Flaherty, J; Hitchcock, MJ; Jaffe, HS; Lalezari, JP; Lietman, PS; Petty, BG; Polis, MA; Wachsman, M	1
Cundy, K; Drew, WL; Fisher, PE; Flaherty, J; Glutzer, E; Hannigan, J; James, C; Lalezari, JP; Martin, JC; Miner, D	1
Arevalo, JF; Chavez de la Paz, E; de Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D	1
Cundy, KC; Hitchcock, MJ; Lee, WA; Li, ZH	1
Cundy, KC; Lee, WA; Li, ZH	1
Lalezari, JP	1
Arevalo, JF; Chavez-de la Paz, E; De Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D; Rahhal, FM	1
Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M	1
Engler, RJ; Katial, RK; Myers, KW	1
Cundy, KC; Hitchcock, MJ; Lacy, SA; Lee, WA; Tellier, P	1
Cundy, KC	1
Cihlar, T; Ho, ES; Lin, DC; Mendel, DB	1
Pavesio, C; Scott, RA	1
Bowers, M	1
Miller, DS	1
Chakrabarti, S; Collingham, KE; Fegan, CD; Milligan, DW; Osman, H	1
Duncan, BA; Ingrosso, A; Mucci, M; Nickens, DJ; Rodríguez, CA; Wolf, DL	1
Bodart, E; de Bilderling, G; De Clercq, E; Lawson, G; Naesens, L; Remacle, M; Snoeck, R; Tuerlinckx, D	1
Araya, CE; Dharnidharka, VR; Fennell, RS; Lew, JF; Neiberger, RE	1
Ida, H; Inui, K; Katsura, T; Tsuji, Y; Uwai, Y	1
Barrios, C; Mir, ML; Puig, JM	1
Castagnola, E; Cirillo, C; Cuzzubbo, D; Dallorso, S; Di Marco, E; Faraci, M; Lanino, E; Moroni, C; Morreale, G	1
Czock, D; Keller, F	1
Gao, Y; Momper, JD; Randhawa, PS; Schonder, KS; Shapiro, R; Venkataramanan, R; Zhao, Y	1
Gattringer, KB; Jäger, W; Kraff, S; Thalhammer, F; Vossen, MG	1

Reviews

4 review(s) available for cidofovir anhydrous and probenecid

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Cidofovir: a new therapy for cytomegalovirus retinitis. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1 Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents	1997
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. Clinical pharmacokinetics, 1999, Volume: 36, Issue:2 Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Interactions; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Insufficiency	1999

Trials

6 trial(s) available for cidofovir anhydrous and probenecid

Article	Year
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue. The Journal of infectious diseases, 1995, Volume: 171, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatine; Cytomegalovirus Infections; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Semen; Virus Shedding	1995
Intravitreal cidofovir (HPMPC) treatment of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome. Ophthalmology, 1995, Volume: 102, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Retina; Uveitis; Vitreous Body	1995
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical Annals of internal medicine, 1997, Feb-15, Volume: 126, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Administration Schedule; Female; Fluid Therapy; Humans; Kidney Diseases; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Renal Agents; Visual Acuity	1997
Anterior nongranulomatous uveitis after intravitreal HPMPC (cidofovir) for the treatment of cytomegalovirus retinitis. Analysis and prevention. Ophthalmology, 1997, Volume: 104, Issue:3 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Glucocorticoids; Granuloma; Humans; Incidence; Injections; Iritis; Mydriatics; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Uricosuric Agents; Vitreous Body	1997
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Apr-01, Volume: 17, Issue:4 Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraocular Pressure; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Recurrence; Renal Agents; Risk Factors; Visual Acuity	1998
Pharmacokinetics and renal effects of cidofovir with a reduced dose of probenecid in HIV-infected patients with cytomegalovirus retinitis. Journal of clinical pharmacology, 2003, Volume: 43, Issue:1 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid	2003

Other Studies

26 other study(ies) available for cidofovir anhydrous and probenecid

Article	Year
Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Analytical biochemistry, 2000, Jul-15, Volume: 283, Issue:1 Topics: Animals; Anion Transport Proteins; Anions; Arylsulfonates; Boron Compounds; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescein; Fluoresceins; Fluorescent Dyes; Glutarates; Humans; Inhibitory Concentration 50; Kinetics; Models, Chemical; Spectrometry, Fluorescence; Time Factors; Transfection	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Immunocompromised Host; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid	1995
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7 Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Chlorocebus aethiops; Cidofovir; Cytosine; Injections, Intravenous; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Probenecid; Virus Diseases	1996
Effect of probenecid on the distribution, metabolism, and excretion of cidofovir in rabbits. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:3 Topics: Administration, Oral; Animals; Antiviral Agents; Autoradiography; Cidofovir; Cytosine; Injections, Intravenous; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Rabbits; Radiography; Tissue Distribution; Uricosuric Agents	1996
Probenecid hypersensitivity in AIDS: a case report. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Cidofovir; Cytosine; Drug Hypersensitivity; Herpes Simplex; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents	1998
Effect of oral probenecid coadministration on the chronic toxicity and pharmacokinetics of intravenous cidofovir in cynomolgus monkeys. Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 44, Issue:2 Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Injections, Intravenous; Kidney; Macaca fascicularis; Male; Organ Size; Organophosphonates; Organophosphorus Compounds; Probenecid	1998
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:3 Topics: Adenine; Alanine; Animals; Anion Transport Proteins; Antiviral Agents; Biological Transport; Carrier Proteins; CHO Cells; Cidofovir; Cricetinae; Cytosine; Humans; Kidney; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Probenecid	2000
Ocular side-effects from systemic HPMPC (Cidofovir) for a non-ocular cytomegalovirus infection. American journal of ophthalmology, 2000, Volume: 130, Issue:1 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Probenecid; Uveitis, Anterior	2000
Cidofovir. BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Interactions; Drug Therapy, Combination; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents	1998
Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Fluorescent Dyes; Fundulidae; In Vitro Techniques; Kidney Tubules, Proximal; Membrane Transport Proteins; Microscopy, Confocal; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents; Xenobiotics	2001
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections. Bone marrow transplantation, 2001, Volume: 28, Issue:9 Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting	2001
Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis. Journal of medical virology, 2005, Volume: 75, Issue:2 Topics: Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Indoles; Injections, Intralesional; Injections, Intravenous; Lung Neoplasms; Organophosphonates; Papilloma; Probenecid	2005
Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy. Pediatric transplantation, 2006, Volume: 10, Issue:1 Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Child; Cidofovir; Contraindications; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Transplantation; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Transplantation, Homologous; Tumor Virus Infections; Uricosuric Agents	2006
Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2). Pharmaceutical research, 2007, Volume: 24, Issue:4 Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Humans; Kidney; Kinetics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Organophosphonates; Probenecid; Tenofovir; Transfection	2007
[Diagnosis of interstitial nephropathy caused by BK virus in renal transplantation. Therapeutic management with cidofovir plus probenecid]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2007, Volume: 27, Issue:6 Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Kidney Transplantation; Male; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections	2007
Low dosage cidofovir without probenecid as treatment for BK virus hamorrhagic cystitis after hemopoietic stem cell transplant. The Pediatric infectious disease journal, 2009, Volume: 28, Issue:1 Topics: Adolescent; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections	2009
[Drug-drug interactions and nephrotoxicity]. Therapeutische Umschau. Revue therapeutique, 2011, Volume: 68, Issue:1 Topics: Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Antirheumatic Agents; Cidofovir; Cisplatin; Contrast Media; Creatinine; Cytosine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney; Organophosphonates; Probenecid; Risk Factors; Uricosuric Agents	2011
Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection. Transplant infectious disease : an official journal of the Transplantation Society, 2013, Volume: 15, Issue:1 Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antiviral Agents; Area Under Curve; BK Virus; Cidofovir; Cross-Over Studies; Cytosine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Half-Life; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections; Viremia	2013
Single-dose pharmacokinetics of cidofovir in continuous venovenous hemofiltration. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:4 Topics: Antiviral Agents; Cidofovir; Critical Illness; Cytosine; Hemofiltration; Humans; Male; Middle Aged; Organophosphonates; Probenecid	2014