cidofovir anhydrous has been researched along with ganciclovir in 277 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.36) | 18.7374 |
| 1990's | 86 (31.05) | 18.2507 |
| 2000's | 102 (36.82) | 29.6817 |
| 2010's | 71 (25.63) | 24.3611 |
| 2020's | 17 (6.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR | 1 |
| Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M | 1 |
| Schneller, SW; Seley, KL; Wu, J | 1 |
| Bédard, J; Chan, L; Nguyen-Ba, P; Quimpère, M; Turcotte, N; Yuen, L | 1 |
| Andrei, G; De Clercq, E; Froeyen, M; Hendrix, C; Herdewijn, P; Snoeck, R; Wang, J | 1 |
| Andrei, G; Balzarini, J; Castro, A; De Clercq, E; Gil, C; Martinez, A; Otero, J; Perez, C; Prieto, C; Snoeck, R | 1 |
| Andrei, G; De Clercq, E; Dimas, K; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Pannecouque, C; Snoeck, R; Stamatiou, G; Witvrouw, M; Zoidis, G | 1 |
| De Clercq, E; Garuti, L; Roberti, M | 1 |
| Balzarini, J; Barral, K; Camplo, M; De Clercq, E; Hider, RC; Neyts, J | 2 |
| Andrei, G; Balzarini, J; De Clercq, E; McGuigan, C; Pathirana, RN; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; García-López, MT; Gerona-Navarro, G; González-Muñiz, R; Pérez de Vega, MJ; Snoeck, R | 2 |
| Andrei, G; Balzarini, J; Barbarić, M; Cetina, M; De Clercq, E; Frković, D; Kralj, M; Mintas, M; Nagl, A; Opacić, N; Pavelić, K; Raić-Malić, S; Snoeck, R; Zorc, B | 1 |
| Andrei, G; Balzarini, J; Barbarić, M; De Clercq, E; Grdisa, M; Hergold-Brundić, A; Mintas, M; Nagl, A; Pavelić, K; Pilepić, V; Snoeck, R; Ursić, S; Zorc, B | 1 |
| Bédard, J; Chan, L; Drouin, M; Falardeau, G; Lachance, H; St-Pierre, A; Yannopoulos, CG | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| De Clercq, E; Glapski, C; Guillerm, G; Muzard, M; Pilard, S | 1 |
| Adrian, J; Chen, X; Cushing, TD; DiMaio, H; Doughan, B; Flygare, J; Jaen, J; Liang, L; Mayorga, V; Mellon, H; Miao, S; Peterson, MG; Powers, JP; Spector, F; Stein, C; Wright, M; Xu, D; Ye, Q | 1 |
| Chou, S; Rawlinson, WD; Scott, GM; Weinberg, A | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pískala, A; Snoeck, R | 1 |
| Adrian, J; Chen, X; Cushing, T; Dimaio, H; Jaen, J; Liang, L; Mayorga, V; Miao, S; Peterson, MG; Powers, JP; Spector, F; Stein, C; Wright, M; Xu, D; Ye, Q | 1 |
| Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE | 1 |
| Andrei, G; Balzarini, J; Cristofoli, WA; De Clercq, E; Knaus, EE; Snoeck, R; Wiebe, LI | 1 |
| Balzarini, J; Clercq, ED; Kralj, M; Makuc, D; Mintas, M; Pavelić, K; Plavec, J; Prekupec, S; Raić-Malić, S; Suman, L | 1 |
| De Clercq, E; Küçükgüzel, I; Küçükgüzel, SG; Rollas, S; Tatar, E | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Mintas, M; Pavelić, K; Raić-Malić, S; Snoeck, R; Sokcević, M; Suman, L | 1 |
| Chou, S; Li, S; Marousek, GI; Van Wechel, LC; Weinberg, A | 1 |
| Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Dzimbeg, G; Ester, K; Kralj, M; Mintas, M; Pavelić, K; Snoeck, R; Zorc, B | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Andrei, G; Balzarini, J; Camarasa, MJ; de Castro, S; Naesens, L; Peromingo, MT; Snoeck, R; Velázquez, S | 1 |
| Allouchi, H; Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB | 1 |
| Balzarini, J; De Clercq, E; Judge, V; Kumar, P; Narang, R; Narasimhan, B; Sharma, D | 1 |
| Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E | 1 |
| Andrei, G; Balzarini, J; Camarasa, MJ; De Castro, S; García-Aparicio, C; Snoeck, R; Velázquez, S | 1 |
| Balzarini, J; Brancale, A; Cirilli, R; Coluccia, A; Giordano, C; La Regina, G; La Torre, F; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Samuele, A; Sansone, A; Silvestri, R; Zanoli, S | 1 |
| Andrei, G; Bayrak, OF; De Clercq, E; Güniz Küçükgüzel, S; Karakuş, S; Küçükgüzel, I; Pannecouque, C; Sahin, F; Snoeck, R | 1 |
| Andrei, G; De Clercq, E; Golankiewicz, B; Ostrowski, T; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; Baraka, MM; el-Sabbagh, OI; Ibrahim, SM; Pannecouque, C; Rashad, AA; Snoeck, R | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Daily, SL; Frederick, SL; Harden, EA; Hartline, CB; Jefferson, G; Kern, ER; Maddry, JA; Prichard, MN; Quenelle, DC; Secrist, JA; Tiwari, KN; Whitley, RJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| De Clercq, E; Ganguly, S; Kumar, KS; Veerasamy, R | 1 |
| Andrei, G; Balzarini, J; Brehová, P; Cihlar, T; De Clercq, E; Dracínský, M; Holý, A; Hui, H; Krecmerová, M; Laflamme, G; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Pomeisl, K; Snoeck, R; Tichý, T | 1 |
| Balzarini, J; De Clercq, E; Dewan, SK; Kumar, P; Narasimhan, B; Pannecouque, C; Yadav, S | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Agrofoglio, LA; Alexandre, JA; Andrei, G; Azzouzi, A; Balzarini, J; Broggi, J; Caillat, C; Deville-Bonne, D; El-Amri, C; Eriksson, S; Lin, J; Meyer, P; Pradère, U; Roy, V; Snoeck, R; Topalis, D | 1 |
| Agrofoglio, LA; Andrei, G; Balzarini, J; Montagu, A; Roy, V; Snoeck, R | 1 |
| Kesel, AJ | 1 |
| Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T | 1 |
| Borysko, K; Breitenbach, J; Drach, JC; Hilfinger, J; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S; Peterson, LW | 1 |
| Andrei, G; Balzarini, J; Karlsson, A; McGuigan, C; Persoons, L; Quintiliani, M; Snoeck, R; Solaroli, N | 1 |
| Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R | 1 |
| Borysko, KZ; Breitenbach, JM; Collins, M; Drach, JC; Hilfinger, JM; Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Serpi, M; Zakharova, VM | 1 |
| Balzarini, J; Głowacka, IE; Piotrowska, DG | 1 |
| Drach, JC; Li, C; Prichard, MN; Quenelle, DC; Zemlicka, J | 1 |
| Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K | 1 |
| Agrofoglio, LA; Andrei, G; Balzarini, J; Roy, V; Sari, O; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Snoeck, R; Tichý, T | 1 |
| Agrofoglio, LA; Andrei, G; Balzarini, J; Hamada, M; Montagu, A; Pradère, U; Roy, V; Sari, O; Snoeck, R | 1 |
| Batta, G; Bereczki, I; Borbás, A; Fejes, Z; Herczegh, P; Kiss-Szikszai, A; Naesens, L; Ostorházi, E; Rőth, E; Rozgonyi, F; Sipos, A; Török, Z | 1 |
| Andrei, G; Babkov, DA; Balzarini, J; Gavryushov, SA; Ivanov, AV; Khandazhinskaya, AL; Kochetkov, SN; Novikov, MS; Pannecouque, C; Paramonova, MP; Seley-Radtke, KL; Snoeck, R; Valuev-Elliston, VT | 1 |
| Andrei, G; Babkov, DA; Balzarini, J; Chizhov, AO; Khandazhinskaya, AL; Novikov, MS; Ozerov, AA; Paramonova, MP; Seley-Radtke, KL; Snoeck, R | 1 |
| Balzarini, J; Chibale, K; Kaur, H; Singh, K | 1 |
| Agrofoglio, LA; Andrei, G; Balzarini, J; Hamada, M; McBrayer, TR; Nolan, SP; Roy, V; Schinazi, RF; Snoeck, R; Urbina-Blanco, C; Whitaker, T | 1 |
| Balzarini, J; Singh, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R | 1 |
| Andrei, G; Kraljević Pavelić, S; Makuc, D; Martinović, T; Mintas, M; Pavelić, K; Plavec, J; Schols, D; Snoeck, R; Stipković Babić, M; Wittine, K | 1 |
| Andrei, G; Babkov, DA; Chizhov, AO; Khandazhinskaya, AL; Novikov, MS; Seley-Radtke, KL; Snoeck, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Andrei, G; Balzarini, J; Bertamino, A; Campiglia, P; Ciaglia, T; di Sarno, V; Gomez-Monterrey, IM; Musella, S; Novellino, E; Ostacolo, C; Sala, M; Scala, MC; Snoeck, R; Spensiero, A | 1 |
| Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Pomeisl, K; Snoeck, R | 1 |
| Agrofoglio, LA; Andrei, G; Bessières, M; Chartier, A; Hervin, V; Lohier, JF; Roy, V; Snoeck, R | 1 |
| Andrei, G; De Jonghe, S; Herdewijn, P; Liu, C; Snoeck, R; Srivastava, P; Wang, M | 1 |
| Andrei, G; De Jonghe, S; Groaz, E; Herdewijn, P; Luo, M; Snoeck, R | 1 |
| Andrei, G; Pertusati, F; Pileggi, E; Schols, D; Serpi, M; Snoeck, R | 1 |
| Andrei, G; Hulpia, F; Liekens, S; Noppen, S; Schols, D; Snoeck, R; Van Calenbergh, S; Vervaeke, P | 1 |
| Claessens, F; Dehaen, W; Helsen, C; Karypidou, K; Pannecouque, C; Persoons, L; Quevedo, MA; Ribone, SR | 1 |
| Abdel-Moty, SG; Andrei, G; Hayallah, AM; Mohammed, AF; Simons, C; Snoeck, R | 1 |
| Andrei, G; Cazin, I; Harej, A; Klobučar, M; Macan, AM; Pavelić, K; Pavelić, SK; Raić-Malić, S; Schols, D; Snoeck, R; Stepanić, V | 1 |
| Balzarini, J; De Clercq, E; Karki, SS; Kulkarni, AA; Kumar, S; Veliyath, SK | 1 |
| Andrei, G; Groaz, E; Herdewijn, P; Luo, M; Snoeck, R | 1 |
| Andrei, G; De Jonghe, S; Groaz, E; Herdewijn, P; Snoeck, R; Zheng, Z | 1 |
| Andrei, G; Aralov, AV; Belyaev, ES; Chistov, AA; Ishmukhametov, AA; Jegorov, AV; Korshun, VA; Kozlovskaya, LI; Matyugina, ES; Nikolaeva, YV; Osolodkin, DI; Shtro, AA; Snoeck, R; Volok, VP | 1 |
| Andrei, G; D'Alonzo, D; De Fenza, M; Esposito, A; Guaragna, A; Snoeck, R; Talarico, G | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Balzarini, J; De Clercq, E; Naesens, L; Neyts, J | 1 |
| Holy, A; Leonhardt, JA; Mead, JR; Morris, JL; Sidwell, RW; Smee, DF | 1 |
| Kern, ER; Patel, P; Simecka, JW | 1 |
| Kern, ER | 1 |
| Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
| De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R | 1 |
| Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T | 1 |
| Datema, R; Yang, H | 1 |
| Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| Chatterjee, S; Gangopadhyay, NN; Whitley, RJ | 1 |
| Cohen, J | 1 |
| Masur, H; Polis, MA | 1 |
| Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF | 1 |
| De Clercq, E; Neyts, J | 1 |
| Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA | 1 |
| Bruggeman, CA; de Clercq, E; Havennith, M; Stals, FS; Zeytinoglu, A | 1 |
| Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A | 1 |
| De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M | 1 |
| De Clercq, E | 1 |
| Balzarini, J; De Clercq, E; Dvoráková, H; Holý, A; Naesens, L; Reymen, D | 1 |
| Jabs, DA | 1 |
| Freeman, WR | 1 |
| Flaherty, JF | 1 |
| Danner, SA | 1 |
| Chatterjee, S; Lakeman, F; Nii, S; Whitley, RJ; Yamada, M; Yoshida, M | 1 |
| De Clercq, E; Kodama, E; Shigeta, S; Suzuki, T | 1 |
| Reusser, P | 1 |
| Bosmans, E; Bron, D; De Clereq, E; Delforge, A; Lagneaux, L; Schols, D; Snoeck, R; Stryckmans, P | 1 |
| Schwartz, DM | 1 |
| Barnett, BB; Sidwell, RW; Smee, DF | 1 |
| Hardy, WD | 1 |
| Kuppermann, BD | 1 |
| Cunningham, ET | 1 |
| Eizuru, Y; Harada, K; Ihara, S; Isashiki, Y; Minamishima, Y | 1 |
| Ganem, D; Kedes, DH | 1 |
| Cherrington, JM; Freeman, WR; Fuller, MD; Jiles, RE; Smith, IL; Spector, SA | 1 |
| Jacobson, MA | 1 |
| Okleberry, KM; Smee, DF; Warren, RP | 1 |
| Bruggeman, CA; Kloover, JS; Stals, FS; Vanagt, WY | 1 |
| Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME | 1 |
| Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG | 1 |
| Katlama, C | 1 |
| Pérez, JL | 1 |
| De Clercq, E; Neyts, J; Pagano, JS; Raab-Traub, N; Sadler, R | 1 |
| Takahashi, K | 1 |
| Ai, E; Freeman, WR; Mueller, AJ; Powell, HC; Rahhal, FM; Smith, IL; Spector, SA; Taskintuna, I | 1 |
| Smith, CL | 1 |
| Baldanti, F; Biron, KK; Gerna, G | 1 |
| Pau, AK | 1 |
| Behnsch, M; Bergmann, F; Grobusch, MP; Liekfeld, A; Schürmann, D | 1 |
| Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ | 1 |
| Cherrington, JM; Cihlar, T; Fuller, MD | 1 |
| Cinatl, J; Scholz, M; Vogel, JU | 1 |
| Cherrington, JM; Cihlar, T; Fuller, MD; Mulato, AS | 1 |
| Aissa, N; Carquin, J; Dewilde, A; Freymuth, F; Houhou-Fidouh, N; Mazeron, MC; Scieux, C; Thouvenot, D | 1 |
| Dunn, JP; Enger, C; Forman, M; Hubbard, L; Jabs, DA | 1 |
| Freeman, WR; Garcia, CR; Torriani, FJ | 1 |
| Cherrington, JM; Drew, WL; Fuller, MD; Lalezari, JP; Lamy, PD; Miner, R; Nuessle, S | 1 |
| Bolton, SG; Dunn, JP; Jabs, DA; Palestine, AG | 1 |
| Cheung, TW; Teich, SA | 1 |
| Cherrington, J; Holtzer, C; Jacobson, MA; Safrin, S; Stanley, H; Wilson, S | 1 |
| Barbeau, D; Bedard, J; Bowlin, TL; May, S; Rando, RF; Yuen, L | 1 |
| Skiest, DJ | 1 |
| Balzarini, J; de Clercq, E; de Vries, E; Franssen, FF; Holý, A; Naesens, L; Overdulve, JP; Smeijsters, LJ | 1 |
| Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD | 1 |
| Drew, WL; Lalezari, JP | 1 |
| Hoy, J | 1 |
| Keating, MR | 1 |
| Au Eong, KG; Beatty, S; Charles, SJ | 1 |
| Blaheta, RA; Cinatl, J; Doerr, HW; Gümbel, HO; Kotchetkov, R; Scholz, M; Vogel, JU; Weimer, E | 1 |
| Bolger, G; Bousquet, C; Cordingley, M; Garneau, M; Kibler, P; Lapeyre, N; Rhéaume, M | 1 |
| Emery, VC | 2 |
| Agut, H; Debré, P; Gautheret-Dejean, A; Grenot, P; Huraux, JM; Manichanh, C | 1 |
| Einsele, H; Hebart, H | 1 |
| Althaus, C; Best, J; Gantke, B; Kersten, A; Theisen, A | 1 |
| Hoffman, VF; Skiest, DJ | 1 |
| Chou, S; Drew, WL; Miner, RC | 1 |
| Distler, A; Ketteler, M; Mertz, A; Offermann, G; Preuschof, L; Schäfer, H; Stöffler-Meilicke, M | 1 |
| Eizuru, Y; Minamishima, Y; Minematsu, T; Mori, S | 1 |
| Boeckh, M; Chuang, EL; Corey, L; Crippa, F; Sale, G | 1 |
| LaBree, L; McDonnell, PJ; Moreira, LB; Oliveira, C; Seitz, B | 1 |
| Castagnola, E; Cristina, E; Dallorso, S; Giacchino, R; Lanino, E | 1 |
| Lawson, CM; Lenzo, JC; Shellam, GR | 1 |
| Blanchet, KD | 1 |
| Torres, G | 2 |
| Cheng, B | 1 |
| Feinberg, J | 1 |
| Highleyman, L | 1 |
| Lee, TA; Malinverni, R; Pleil, AM; Ramsey, SD; Steger, PJ; Sullivan, SD; Veenstra, DL; Williamson, T | 1 |
| Basara, N; Kiehl, MG | 1 |
| Castagnola, E; Chierici, M; Cristina, E; Lanino, E; Miano, M; Morreale, G | 1 |
| Alkan, S; Bhorade, SM; Garrity, ER; Husain, AN; McCabe, MA; Norwick, L; Sandesara, C; Vigneswaran, WT; Yeldandi, V | 1 |
| Boulad, F; Cihlar, T; George, D; Kiehn, TE; Lin, DC; Polsky, B; Prasad, VK; Regan, A; Seo, SK | 1 |
| Bidanset, DJ; Hartline, CB; Kern, ER; Rybak, RJ | 2 |
| Salmon-Ceron, D | 1 |
| De Clercq, E; Naesens, L | 1 |
| Chou, SW | 1 |
| Williams, IG | 1 |
| Di Perri, G; Maiello, A; Quario, M; Racca, D; Sinicco, A; Zeme, DA | 1 |
| Kimberlin, DW | 1 |
| Zaia, JA | 2 |
| Mitchell, SM; Obi, AA; Zambarakji, HJ | 1 |
| Emery, VC; Leśnikowski, ZJ; Olejniczak, A; Paradowska, E; Przepiórkiewicz, M | 1 |
| Bidanset, DJ; Kern, ER; Kushner, NL; Long, MC; Williams, SL | 1 |
| Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW | 1 |
| Boivin, G; Sergerie, Y | 1 |
| Boeckh, M; Nichols, WG; Papanicolaou, G; Rubin, R; Wingard, JR; Zaia, J | 1 |
| Baldanti, F; Campanini, G; Comolli, G; Gerna, G; Lilleri, D; Ridolfo, AL; Rusconi, S | 1 |
| Eksborg, S | 1 |
| Alain, S; Belloc, S; Brouet, JC; Ducancelle, A; Malphettes, M; Mazeron, MC; Petit, F; Sanson Le Pors, MJ; Scieux, C | 1 |
| Dunn, JP; Foster, G; Jabs, DA; Kuppermann, BD; Martin, DF; Van Natta, M; Zong, A | 1 |
| Clarke, HE; Maggs, DJ | 1 |
| Clark, DA; Emery, VC; Fryer, JF; Griffiths, PD | 1 |
| De Clercq, E; Friedrichs, C; Gaspar, G; Neyts, J; Wutzler, P | 1 |
| Baldanti, F; Gerna, G; Lurain, N | 1 |
| Alain, S; Denes, E; Magy, L; Pradeau, K; Ranger-Rogez, S; Weinbreck, P | 1 |
| Ljungman, P | 1 |
| Freitag, M; Herget, T; Kupfer, R; Marschall, M; Morbitzer, M; Stamminger, T | 1 |
| Dediulescu, DF; Dediulescu, L | 1 |
| Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM | 1 |
| Buonfrate, D; Cesaro, S; Cusinato, R; Manzardo, C; Mengoli, C; Messina, C; Palù, G; Tridello, G; Zhou, X | 1 |
| Boivin, G; Gilbert, C | 1 |
| Moriuchi, H; Moriuchi, M | 1 |
| Chou, S; Drew, WL; Marousek, GI; Miner, RC | 1 |
| Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K | 1 |
| Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P | 1 |
| Eizuru, Y | 1 |
| Michaels, MG | 1 |
| Bernstein, DI; Bravo, FJ; Cardin, RD | 1 |
| Chou, S; Marousek, GI | 1 |
| Chou, S; Li, S; Marousek, G; Weinberg, A | 1 |
| Boucher, HW; Torres-Madriz, G | 1 |
| Asano-Mori, Y; Chiba, S; Kako, S; Kanda, Y; Kurokawa, M; Motokura, T; Oshima, K; Shiraki, K; Watanabe, T | 1 |
| Casier, S; Filler, G; Grimmer, J; Moussa, M; Rehman, F; Sharma, AP | 1 |
| Járay, J; Péter, A; Telkes, G; Varga, M | 1 |
| Bunjes, D; Härter, G; Mertens, T; Michel, D; Schreiber, A; Schubert, A | 1 |
| Cowan, MJ; Dvorak, CC; Horn, B; Weintrub, PS | 1 |
| Chou, S; Lurain, NS | 1 |
| Kern, ER; Prichard, MN | 1 |
| Agut, H | 1 |
| Capobianchi, A; Foà, R; Gentile, G; Girmenia, C; Iori, AP; Mauro, FR; Micozzi, A; Torelli, GF | 1 |
| Bowlin, TL; Chou, S; Marousek, G | 1 |
| Chavala, S; Miller, MB; Moss, HB; Say, E | 1 |
| Carmichael, A; Goldsmith, PM; Husain, MM; Middleton, SJ; Zhang, H | 1 |
| Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Laib Sampaio, K | 1 |
| Bastide, C; Bruyère, F; Chandenier, J; Desoubeaux, G; Fourcade, C; Guy, L; Karsenty, G; Lachaud, L; Lavigne, JP; Malavaud, S; Sotto, A | 1 |
| Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD | 1 |
| Boivin, G; Piret, J | 1 |
| Gregg, K; Hakki, M; Kaul, DR | 1 |
| Chou, S; Ercolani, RJ; Lefterova, MI; Pinsky, BA; Sahoo, MK; Strasfeld, LM | 1 |
| Black, DH; Brush, LA; Eberle, R; Maxwell, LK; Mccormack, KA; Payton, ME; Ritchey, JW; Wright, G | 1 |
| Iapadre, G; Lasorella, S; Mareri, A; Maresca, M; Nigro, G; Tambucci, R | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Sampaio, KL | 1 |
| Chou, S; Ercolani, RJ; Lanier, ER | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Hofmann, J; Imrich, E; Jahn, G; Sampaio, KL | 1 |
| Choo, DI; Nassar, M; Pordal, A; Quimby, C; Sidell, D; Ward, JA | 1 |
| Agut, H; Bonnafous, P; Gautheret-Dejean, A | 1 |
| Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY | 1 |
| Bruminhent, J; Rotjanapan, P; Watcharananan, SP | 1 |
| Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B | 1 |
| Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L | 1 |
| Meesing, A; Razonable, RR | 1 |
| DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P | 1 |
| Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG | 1 |
| Chiereghin, A; Contini, C; Felici, S; Gabrielli, L; La Corte, R; Lazzarotto, T; Maritati, M; Piccirilli, G; Turello, G | 1 |
| Aguilar-Guisado, M; Berastegui-Cabrera, J; Marrugal-Lorenzo, JA; Merino, L; Pachón, J; Sánchez-Céspedes, J | 1 |
| Anderson, TK; Chien, M; Jockusch, S; Ju, J; Kirchdoerfer, RN; Kumar, S; Li, X; Russo, JJ; Tao, C | 1 |
| Alfares, M; Ambinder, RF; Arav-Boger, R; Avery, RK; Forman, MS; Jones, RJ; Lees, L; Mehta Steinke, SA; Ostrander, D; Shedeck, A; Shoham, S; Valsamakis, A | 1 |
| Chou, S | 1 |
| Cho, SY; Choi, SM; Jung, JY; Kim, HJ; Kim, M; Lee, DG; Nho, D; Oh, EJ | 1 |
| Blumberg, EA; Halpern-Cohen, V | 1 |
| Alain, S; Aranzamendi, M; Berengua, C; Bodro, M; Cofan, F; Cordero, E; Esteva, C; Fernández Avilés, F; Fernández Sabé, N; Hantz, S; Len, O; Linares, L; Marcos, MÁ; Martin-Davila, P; Moreno, A; Mosquera, MM; Navarro Gabriel, M; Pérez Jiménez, AB; Plault, N; Rodríguez, C; Rovira, M; Sánchez-Palomino, S; Santos Bravo, M; Suarez-Lledó, M; Vidal, E | 1 |
| Bowlin, TL; Hussein, ITM; Tollefson, AE; Toth, K | 1 |
| Carter, RT; Ineck, NE; Lewin, AC; Liu, CC; Marino, ME; Mironovich, MA; Yoon, A | 1 |
| Aydamirov, AS; Erdem, E; Harbiyeli, II; Ozturk, G; Yagmur, M; Yarkin, F | 1 |
| Kleiboeker, SB | 1 |
53 review(s) available for cidofovir anhydrous and ganciclovir
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1991 |
Promising new treatments for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections, Intralesional; Organophosphonates; Organophosphorus Compounds | 1995 |
Antivirals for the treatment of herpesvirus infections.
Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1993 |
Management of cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1995 |
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine | 1996 |
New therapies for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Administration Routes; Drug Therapy, Combination; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1996 |
Management strategies for patients with cytomegalovirus retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Interactions; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds | 1997 |
Therapeutic options for resistant cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Recurrence; Thionucleotides | 1997 |
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Management of CMV retinitis in HIV infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Prodrugs; Prospective Studies; Recurrence | 1997 |
Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.
Topics: Antiviral Agents; Cidofovir; Codon; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Viral Structural Proteins | 1997 |
[Recent advances in antiviral drugs--antiviral agents to HCMV, HHV-6, and HHV-7].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Purines; Thymidine Kinase | 1998 |
Local therapy for cytomegalovirus retinitis.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1998 |
Treatment of cytomegalovirus diseases.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Cidofovir in the treatment of cytomegalovirus (CMV) retinitis.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds | 1998 |
Cytomegalovirus infection in patients with HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART).
Topics: Antiviral Agents; Biomarkers; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Diagnosis, Differential; Foscarnet; Ganciclovir; Herpesviridae; Humans; Incidence; Organophosphonates; Organophosphorus Compounds; Risk Factors | 1999 |
Cytomegalovirus: disease syndromes and treatment.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System Diseases; Chorioretinitis; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds; Pneumonia; Sexually Transmitted Diseases, Viral | 1999 |
Management of CMV infections in HIV-infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Antiviral agents for non-human immunodeficiency virus infections.
Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir | 1999 |
Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retinal Detachment | 1999 |
Cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds | 1998 |
Cytomegalovirus infection following stem cell transplantation.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency | 1999 |
Therapeutic developments in cytomegalovirus retinitis.
Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir | 2000 |
Progress in understanding cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Forecasting; Foscarnet; Ganciclovir; Humans; Incidence; Organophosphonates; Organophosphorus Compounds | 2001 |
Economic evaluation of systemic treatments for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Economics, Pharmaceutical; Foscarnet; Ganciclovir; Humans; Models, Economic; Organophosphonates; Organophosphorus Compounds; Switzerland; Treatment Failure | 2001 |
Cytomegalovirus infection: the point in 2001.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Monitoring; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Population Surveillance; Predictive Value of Tests; Prevalence; Risk Factors; Valganciclovir | 2001 |
Recent developments in herpesvirus therapy.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine | 2001 |
Cytomegalovirus drug resistance and clinical implications.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Incidence; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2001 |
Management of CMV disease in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Encephalitis, Viral; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2002 |
[Drugs against human cytomegalovirus].
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drugs, Investigational; Female; Foscarnet; Ganciclovir; Global Health; Humans; Infectious Disease Transmission, Vertical; Naphthalenesulfonates; Organophosphonates; Organophosphorus Compounds; Pregnancy; Pregnancy Complications, Infectious; Thionucleotides; Valacyclovir; Valganciclovir; Valine | 2002 |
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunotherapy; Lymphocyte Depletion; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning | 2003 |
The pharmacokinetics of antiviral therapy in paediatric patients.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases | 2003 |
Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Virus Replication | 2004 |
Treatment of adenovirus infections in the immunocompromised host.
Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Prognosis; Ribavirin; Severity of Illness Index; Transplantation Immunology; Treatment Outcome; Vidarabine | 2004 |
[Antiherpetic therapy].
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine | 2005 |
[Treatment of HHV-6 and HHV-7 infections].
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunoglobulins; Lymphocyte Transfusion; Organophosphonates; Roseolovirus Infections | 2006 |
[Mechanism of drug-resistance in human cytomegalovirus].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2007 |
Treatment of congenital cytomegalovirus: where are we now?
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Humans; Infant, Newborn; Organophosphonates; Pregnancy; Valganciclovir | 2007 |
Immunocompromised hosts: perspectives in the treatment and prophylaxis of cytomegalovirus disease in solid-organ transplant recipients.
Topics: Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Transplantation; Valganciclovir | 2008 |
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir | 2008 |
Antiviral treatment of cytomegalovirus infection and resistant strains.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Thionucleotides; Valganciclovir | 2009 |
Antiviral drug resistance of human cytomegalovirus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genome, Viral; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, DNA | 2010 |
The search for new therapies for human cytomegalovirus infections.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication | 2011 |
Deciphering the clinical impact of acute human herpesvirus 6 (HHV-6) infections.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Immunity, Cellular; Infant; Organophosphonates; Roseolovirus Infections; Viral Load; Virus Latency | 2011 |
[Non-antibiotic anti-infectious treatments in urology].
Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir | 2013 |
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates | 2014 |
Anti-viral therapy for congenital cytomegalovirus infection: pharmacokinetics, efficacy and side effects.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompetence; Organophosphonates; Treatment Outcome | 2016 |
Human Herpesviruses 6A, 6B, and 7.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunocompromised Host; Organophosphonates; Roseolovirus Infections; Transplant Recipients; Virus Latency | 2016 |
New Developments in the Management of Cytomegalovirus Infection After Transplantation.
Topics: Acetates; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Organ Transplantation; Quinazolines; Valganciclovir | 2018 |
New Perspectives on Antimicrobial Agents: Maribavir.
Topics: Adult; Anti-Infective Agents; Antiviral Agents; Benzimidazoles; Child; Cidofovir; Cytomegalovirus Infections; Dichlororibofuranosylbenzimidazole; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Valganciclovir | 2022 |
7 trial(s) available for cidofovir anhydrous and ganciclovir
| Article | Year |
|---|---|
Phase I study of combination therapy with intravenous cidofovir and oral ganciclovir for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Ganciclovir; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1999 |
The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Double-Blind Method; Drug Evaluation; Drug Implants; Female; Ganciclovir; Humans; Infusions, Parenteral; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Survival Rate; Treatment Outcome; Uveitis; Visual Acuity; Vitreous Hemorrhage | 2001 |
Update on treatment of CMV retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Eye; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic | 1995 |
Opportunistic infection highlights from the 35th ICAAC.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia | 1995 |
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Syndromes; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Transplantation, Homologous; Treatment Failure; Viremia; Virus Activation | 2001 |
Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anesthesia, General; Anesthesia, Local; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Female; Ganciclovir; Humans; Infusions, Intravenous; Intraoperative Complications; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Prospective Studies; Visual Acuity; Vitreous Hemorrhage | 2004 |
Evaluation of compounded cidofovir, famciclovir, and ganciclovir for the treatment of feline herpesvirus ocular surface disease in shelter-housed cats.
Topics: Animals; Antiviral Agents; Cat Diseases; Cats; Cidofovir; Famciclovir; Ganciclovir; Herpesviridae Infections; Ophthalmic Solutions; Ulcer; Varicellovirus; Weight Gain | 2023 |
217 other study(ies) available for cidofovir anhydrous and ganciclovir
| Article | Year |
|---|---|
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells | 1989 |
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells | 1996 |
Carbocyclic oxetanocins lacking the C-3' methylene.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses | 1997 |
Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity.
Topics: Antiviral Agents; Cytomegalovirus; Microbial Sensitivity Tests; Nucleotides; Organophosphorus Compounds; Stereoisomerism; Structure-Activity Relationship | 1998 |
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.
Topics: Animals; Antiviral Agents; Cyclohexanes; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Models, Molecular; Molecular Mimicry; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship | 2000 |
Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Benzothiadiazines; Chlorocebus aethiops; Cyclic S-Oxides; Cytomegalovirus; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; T-Lymphocytes; Vero Cells | 2000 |
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
Topics: Bacteria; Cell Division; Cell Line; Formazans; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazolium Salts; Thiosemicarbazones; Tumor Cells, Cultured; Viruses | 2002 |
Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Structure-Activity Relationship; T-Lymphocytes; Tumor Cells, Cultured; Viral Plaque Assay | 2002 |
Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives.
Topics: Antiviral Agents; Deferiprone; Dideoxynucleosides; Drug Design; Herpesvirus 1, Human; Models, Molecular; Pyridones; Structure-Activity Relationship | 2003 |
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.
Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Furans; Humans; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication | 2004 |
Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.
Topics: Antiviral Agents; Azetidines; Cytomegalovirus; Lactams | 2004 |
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.
Topics: Amino Acids; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Hydantoins; Hydroxyurea; Stereoisomerism; Structure-Activity Relationship | 2005 |
Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids.
Topics: Acetamides; Adamantane; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Cytomegalovirus; Drug Screening Assays, Antitumor; Humans; Hydroxamic Acids; Mice; Molecular Structure; Structure-Activity Relationship | 2005 |
Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors.
Topics: Antiviral Agents; Cytomegalovirus; Drug Design; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Models, Chemical; Models, Molecular; Molecular Structure; Naphthyridines | 2005 |
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
Topics: Alanine; Antiviral Agents; Azetidines; Cells, Cultured; Cytomegalovirus; Humans; Lactams; Protease Inhibitors; Structure-Activity Relationship | 2005 |
Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives.
Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Chlorocebus aethiops; Deferiprone; HeLa Cells; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; HIV-2; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Pyridones; Structure-Activity Relationship; Vero Cells | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
Topics: Adenosylhomocysteinase; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Deoxyadenosines; Herpesvirus 3, Human; Humans; Nucleosides; Stereoisomerism; Structure-Activity Relationship | 2006 |
Discovery of a novel series of inhibitors of human cytomegalovirus primase.
Topics: Antiviral Agents; Bone Marrow; Cell Line; Cytomegalovirus; DNA Primase; Enzyme Inhibitors; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship | 2006 |
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Multiple; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2007 |
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA Viruses; Humans; Mice; Organophosphonates; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Triazines | 2007 |
SAR studies on a novel series of human cytomegalovirus primase inhibitors.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Cytomegalovirus; DNA Primase; DNA Replication; Drug-Related Side Effects and Adverse Reactions; Humans; Inhibitory Concentration 50; Pyrimidines; Rats; Structure-Activity Relationship; Viral Load | 2007 |
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells | 2007 |
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
Topics: Alkynes; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Transfection; Uridine | 2007 |
Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Cytostatic Agents; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Molecular Mimicry; Positron-Emission Tomography; Pyrimidine Nucleosides; Pyrimidines; Structure-Activity Relationship | 2007 |
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
Topics: Animals; Antitubercular Agents; Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Thiourea; Triazoles | 2008 |
Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Pyrimidines; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship | 2007 |
Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens.
Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Mutation; Phenotype | 2007 |
Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).
Topics: Antiviral Agents; Cell Line; Cell Survival; Cytomegalovirus; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship | 2007 |
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
Topics: Antiviral Agents; Cell Line; Cytosine; DNA Viruses; Drug Resistance, Viral; Esters; Humans; Magnetic Resonance Spectroscopy; Prodrugs; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship | 2007 |
The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Primaquine; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Urea | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thymidine; Urea | 2008 |
Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Herpes Zoster; Herpesvirus 3, Human; Humans; Imidazoles; Lung; Molecular Structure; Pyridines; Structure-Activity Relationship | 2008 |
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Aspergillus niger; Bacillus subtilis; Candida albicans; Cells, Cultured; Chlorocebus aethiops; Drug Design; Escherichia coli; HeLa Cells; Herpesvirus 1, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vero Cells | 2009 |
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship | 2009 |
4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytomegalovirus; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Naphthalenesulfonates; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Virus Replication | 2009 |
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
Topics: Amino Acids; Animals; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Drug Resistance, Viral; Enterovirus B, Human; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Lymphocytes; Mice; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones; Virus Replication | 2009 |
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Sulfonamides; Thiourea; Viruses | 2009 |
Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues.
Topics: Acyclovir; Antiviral Agents; Cell Line; Guanine; Herpesvirus 3, Human; Humans | 2009 |
Synthesis and antiviral activity of new pyrazole and thiazole derivatives.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Microbial Sensitivity Tests; Pyrazoles; Structure-Activity Relationship; Thiazoles; Vero Cells; Viruses | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Cells, Cultured; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Fluorescent Antibody Technique, Indirect; Herpesviridae; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Molecular Structure; Pyrimidine Nucleosides; Viral Proteins; Virus Replication | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones.
Topics: Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Quinazolines; Schiff Bases; Spectrophotometry, Infrared | 2010 |
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
Topics: Adenine; Antiviral Agents; Cell Proliferation; Cells, Cultured; Esters; Herpesviridae; Humans; Organophosphorus Compounds; Poxviridae; Prodrugs; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Virology | 2010 |
4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation.
Topics: Animals; Anti-Infective Agents; Benzenesulfonates; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Dogs; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
Topics: Antiviral Agents; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Herpesviridae; Humans; Ligands; Models, Molecular; Molecular Structure; Nucleoside-Phosphate Kinase; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase | 2011 |
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; Cyclization; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Vero Cells; Viruses | 2011 |
Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative.
Topics: Anti-Bacterial Agents; Benzaldehydes; Cell Line, Tumor; Chromatography, Thin Layer; Cytomegalovirus; Hepacivirus; Herpesvirus 3, Human; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Retinoids; Stereoisomerism; Structure-Activity Relationship; Thiosemicarbazones | 2011 |
New prodrugs of Adefovir and Cidofovir.
Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus | 2011 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine | 2011 |
Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.
Topics: Amides; Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Floxuridine; Hepacivirus; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Phosphoric Acids; Stereoisomerism; Structure-Activity Relationship; Virus Replication | 2011 |
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses | 2011 |
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus | 2011 |
Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
Topics: Animals; Antiviral Agents; Cell Line; Cytostatic Agents; Drug Design; Humans; Inhibitory Concentration 50; Mice; Nucleotides; Triazoles; Viruses | 2012 |
Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
Topics: Administration, Oral; Animals; Antiviral Agents; Cowpox virus; Cyclopropanes; Cytomegalovirus; Guanine; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; HIV-1; Humans; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Vaccinia virus | 2012 |
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses | 2012 |
Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines.
Topics: Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; Deoxyuridine; Humans; Inhibitory Concentration 50; Virus Replication; Viruses | 2012 |
Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.
Topics: Animals; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA Viruses; Guanine; Humans; Hypoxanthine; Hypoxanthines; Nucleosides; Organophosphonates; Phosphorous Acids; Prodrugs; Structure-Activity Relationship | 2012 |
Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphono-but-2'-en-1'-yl]purine nucleosides.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; DNA Viruses; Dogs; Drug Design; Drug Discovery; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Organophosphonates; Prodrugs; Purine Nucleosides; RNA Viruses; Vero Cells; Viral Plaque Assay | 2012 |
Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities.
Topics: Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cell Survival; Drug Resistance, Viral; Gram-Positive Bacteria; Herpesvirus 1, Human; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Isoindoles; Microbial Sensitivity Tests; o-Phthalaldehyde; Teicoplanin | 2012 |
N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Binding Sites; Cell Line; Cinnamates; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Mutation; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil | 2013 |
Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof.
Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Humans; Receptors, Virus; Structure-Activity Relationship; Uracil; Virus Replication | 2013 |
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship | 2013 |
Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides.
Topics: Antiviral Agents; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Prodrugs; Structure-Activity Relationship; Viruses | 2013 |
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues.
Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus | 2015 |
Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Purines; Structure-Activity Relationship | 2015 |
Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.
Topics: Acetamides; Antiviral Agents; Cell Line; Cell Proliferation; Cytomegalovirus; DNA Viruses; Drug Evaluation, Preclinical; Herpesvirus 3, Human; Humans; RNA Viruses; Structure-Activity Relationship; Uracil; Virus Replication | 2015 |
Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor.
Topics: Antiviral Agents; Cell Line; Cell Proliferation; Cells, Cultured; Drug Design; Herpesvirus 3, Human; Humans; Indoles; Molecular Structure; Virus Replication | 2016 |
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship | 2017 |
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.
Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Humans; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Simplexvirus | 2017 |
Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates.
Topics: Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Coronavirus 229E, Human; Dose-Response Relationship, Drug; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Structure-Activity Relationship | 2018 |
Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates.
Topics: Antiviral Agents; Cyclopentanes; DNA Viruses; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Organophosphonates; Structure-Activity Relationship | 2018 |
Amidate Prodrugs of Cyclic 9-(
Topics: | 2018 |
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.
Topics: Antiviral Agents; Cell Line; DNA Viruses; Drug Stability; Humans; Nucleosides; Organophosphonates; Prodrugs; RNA Viruses; Structure-Activity Relationship | 2018 |
Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides.
Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Purine Nucleosides; Small Molecule Libraries; Structure-Activity Relationship; Vaccinia virus | 2018 |
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents.
Topics: Antiviral Agents; Catalytic Domain; Cell Line, Tumor; Coronavirus; Coronavirus 3C Proteases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Triazoles; Viral Proteins | 2018 |
Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.
Topics: Acyclovir; Antiviral Agents; Guanine; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Models, Molecular | 2019 |
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives.
Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles; Viruses | 2019 |
Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-
Topics: | 2013 |
Amidate Prodrugs of
Topics: | 2020 |
Influence of 4'-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2.
Topics: | 2021 |
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; DNA Viruses; Dogs; Humans; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Oxazines; SARS-CoV-2; Structure-Activity Relationship; Vero Cells; Virus Replication | 2021 |
Synthesis and antiviral properties of biomimetic iminosugar-based nucleosides.
Topics: Antiviral Agents; Biomimetics; Molecular Conformation; Nucleosides; Piperidines | 2022 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1992 |
Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Combinations; Ganciclovir; Immunologic Deficiency Syndromes; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins | 1992 |
Immunotoxic potential of antiviral drugs: effects of ganciclovir and (S)-1-(3-hydroxy-2-phosphonylmethoxy propyl) cytosine on lymphocyte transformation and delayed-type hypersensitivity responses.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Concanavalin A; Cytosine; Ganciclovir; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Phytohemagglutinins; Specific Pathogen-Free Organisms | 1992 |
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay | 1991 |
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds | 1991 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin | 1991 |
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine | 1991 |
Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice.
Topics: Animals; Antiviral Agents; Brain Stem; Cidofovir; Cytosine; Drug Administration Schedule; Encephalitis; Female; Ganciclovir; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Premedication | 1991 |
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine | 1990 |
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).
Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA; DNA Replication; DNA, Viral; Flow Cytometry; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1990 |
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents.
Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Evaluation Studies as Topic; Ganciclovir; Humans; Interferons; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Radioimmunoassay; Staphylococcal Protein A; Time Factors; Virus Replication | 1994 |
AIDS therapy. New hope against blindness.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Blindness; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; RNA, Antisense | 1995 |
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds | 1995 |
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1994 |
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis; Time Factors | 1994 |
Comparative effect of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine treatment on cytomegalovirus-induced interstitial pneumonitis in allogeneic bone marrow transplant recipient rats.
Topics: Animals; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Male; Organophosphonates; Organophosphorus Compounds; Pulmonary Fibrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine.
Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation | 1993 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice.
Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Ganciclovir; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1993 |
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds | 1995 |
Treatment of cytomegalovirus retinitis in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Routes; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Retinitis | 1996 |
New developments in the treatment of CMV retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Injections; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1996 |
Current and experimental therapeutic options for cytomegalovirus disease.
Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds | 1996 |
A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 1996 |
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection.
Topics: Bone Marrow Cells; Cidofovir; Cytokines; Cytomegalovirus; Cytosine; Ganciclovir; Humans; Lipopolysaccharides; Organophosphonates; Organophosphorus Compounds; Stromal Cells; Virus Replication | 1996 |
Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Ganciclovir; Immunotoxins; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Ricin; Tumor Cells, Cultured | 1996 |
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Prognosis; Retinitis | 1997 |
Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA | 1997 |
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA Probes; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Methylurea Compounds; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Phorbol Esters; Pyridines; Sarcoma, Kaposi; Tumor Cells, Cultured; Valine; Virus Replication | 1997 |
High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor) | 1997 |
Metabolism of ganciclovir and cidofovir in cells infected with drug-resistant and wild-type strains of murine cytomegalovirus.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Ganciclovir; Mice; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Time Factors; Tumor Cells, Cultured | 1997 |
Effective treatment of experimental cytomegalovirus-induced encephalo-meningitis in immunocompromised rats with HPMPC.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; Immune Sera; Immunocompromised Host; Male; Meninges; Meningitis, Viral; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Inbred BN; Time Factors | 1997 |
Drugs for non-HIV viral infections.
Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases | 1997 |
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Male; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis, DNA | 1997 |
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency | 1997 |
The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice.
Topics: Adolescent; Animals; Antiviral Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Female; Ganciclovir; Genes, p53; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Injections, Intralesional; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Tumor Virus Infections | 1998 |
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Treatment Failure; Vitreous Body | 1998 |
Interpreting human cytomegalovirus antiviral drug susceptibility testing: the role of mixed virus populations.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds | 1998 |
New issues in the management of cytomegalovirus retinitis in AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1998 |
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Lung Diseases; Nervous System Diseases; Organophosphonates; Organophosphorus Compounds; Retinitis | 1998 |
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Recombination, Genetic; Virus Replication | 1998 |
A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.
Topics: Amino Acid Sequence; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Repression; Exonucleases; Ganciclovir; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Point Mutation; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication | 1998 |
[Comparison of the in vitro sensitivity to cidofovir and ganciclovir of clinical cytomegalovirus isolates. Coordinated Action Group 11].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 1998 |
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Female; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Prospective Studies; Survival Rate; Urine; Viremia | 1998 |
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Discontinuing anticytomegalovirus therapy in patients with immune reconstitution after combination antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Female; Ganciclovir; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Viral Load | 1998 |
A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors.
Topics: Antiviral Agents; Cidofovir; Colorimetry; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Fibroblasts; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tetrazolium Salts; Virus Replication | 1999 |
Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.
Topics: Adenine; Animals; Antimalarials; Cidofovir; Cytosine; Erythrocytes; Ganciclovir; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Plasmodium falciparum; Structure-Activity Relationship | 1999 |
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Ganciclovir; Genotype; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Prospective Studies; Retinitis; Viral Load; Viral Proteins | 1999 |
The antisense oligonucleotide ISIS 2922 prevents cytomegalovirus-induced upregulation of IL-8 and ICAM-1 in cultured human fibroblasts.
Topics: Antiviral Agents; Cells, Cultured; Chemotaxis, Leukocyte; Cidofovir; Cytomegalovirus Infections; Cytosine; Fibroblasts; Foscarnet; Ganciclovir; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-8; Neutrophils; Oligonucleotides, Antisense; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Up-Regulation | 2000 |
Acute murine cytomegalovirus infection: a model for determining antiviral activity against CMV induced hepatitis.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Body Weight; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Ganciclovir; Hepatitis, Viral, Animal; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1999 |
Susceptibility of human herpesvirus 6 to antiviral compounds by flow cytometry analysis.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Flow Cytometry; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 2000 |
[Stopping secondary prevention in AIDS patients with inactive CMV retinitis treated with HAART (highly active antiretroviral therapy)].
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 2000 |
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Ganciclovir; Gene Deletion; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases; Transfection | 2000 |
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Fatal Outcome; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pneumonia, Viral; Polymerase Chain Reaction; Postoperative Complications | 2000 |
Isolation and analysis of an aciclovir-resistant murine cytomegalovirus mutant.
Topics: Acyclovir; Amino Acid Substitution; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Codon; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Ganciclovir; Inhibitory Concentration 50; Mice; Muromegalovirus; Mutation; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Virus Replication | 2001 |
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Treatment Outcome; Virus Activation | 2001 |
In vitro effects of antiviral agents on human keratocytes.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Colorimetry; Corneal Stroma; Cytosine; Dose-Response Relationship, Drug; Fibroblasts; Ganciclovir; Humans; Idoxuridine; Microscopy, Phase-Contrast; Organophosphonates; Organophosphorus Compounds; Trifluridine | 2001 |
Failure of cidofovir to reduce CMV-antigenemia in a child transplanted from a matched unrelated donor.
Topics: Adenoviridae; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Ganciclovir and cidofovir treatment of cytomegalovirus-induced myocarditis in mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Muromegalovirus; Myocarditis; Organophosphonates; Organophosphorus Compounds | 2001 |
CMV retinitis: a clinical management update.
Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds; Patient Participation; Vitreous Body | 1996 |
Second National Retrovirus conference: a further report.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cause of Death; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Paclitaxel; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Tuberculosis | 1995 |
Advances in the treatment of CMV.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Eye; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Quality of Life | 1995 |
Fomivirsen.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Foscarnet; Ganciclovir; Health Services Accessibility; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides | 1998 |
Strategies for management of cytomegalovirus (CMV) infection after allogeneic bone marrow transplantation: the "doubling of baseline CMV pp65 antigenemia" and the "cidofovir as rescue treatment approaches.
Topics: Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Recurrence; Salvage Therapy; Time Factors; Transplantation, Homologous; Viral Matrix Proteins; Viremia | 2001 |
Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients.
Topics: Adult; Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Female; Ganciclovir; Humans; Illinois; Immunization, Passive; Lung Transplantation; Male; Middle Aged; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Predictive Value of Tests; Prospective Studies; Reagent Kits, Diagnostic; Sensitivity and Specificity; Survival Analysis; Syndrome; Viral Load | 2001 |
Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance.
Topics: Antiviral Agents; Bone Marrow Transplantation; Cerebral Ventricles; Child; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Combinations; Drug Resistance, Viral; Encephalitis, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds | 2001 |
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2001 |
A case of flare syndrome.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine | 2001 |
Antiviral therapy for cytomegalovirus infections in pediatric patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Infant; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Time Factors | 2002 |
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine | 2002 |
Successful treatment of varicella zoster virus retinitis with aggressive intravitreal and systemic antiviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Foscarnet; Ganciclovir; Herpes Zoster Ophthalmicus; Humans; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Retinitis; Vitreous Body | 2002 |
Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds | 2003 |
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds | 2003 |
Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR.
Topics: Antiviral Agents; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Regression Analysis | 2003 |
Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response.
Topics: Antigens, Viral; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Immunity, Cellular; Lung; Lung Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 2004 |
Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; Female; Foscarnet; Ganciclovir; Humans; Lymphoma, T-Cell; Molecular Epidemiology; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA | 2004 |
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication | 2004 |
Susceptibility of porcine cytomegalovirus to antiviral drugs.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA, Viral; Fluorescent Antibody Technique, Indirect; Foscarnet; Ganciclovir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Swine; Virus Replication | 2004 |
Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction | 2004 |
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication | 2004 |
Successful treatment of human herpesvirus 6 encephalomyelitis in immunocompetent patient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Encephalomyelitis; Female; Ganciclovir; Herpesvirus 6, Human; Humans; Immunocompetence; Organophosphonates; Organophosphorus Compounds; Roseolovirus Infections | 2004 |
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication | 2004 |
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication | 2005 |
Cidofovir for cytomegalovirus reactivation in pediatric patients after hematopoietic stem cell transplantation.
Topics: Adolescent; Antigens, Viral; Antiviral Agents; Child; Cidofovir; Creatinine; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Premedication; Virus Activation | 2005 |
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure.
Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Molecular Sequence Data; Mutation; Organophosphonates | 2005 |
Maribavir sensitivity of cytomegalovirus isolates resistant to ganciclovir, cidofovir or foscarnet.
Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Viral Proteins | 2006 |
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates | 2007 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Fatal Outcome; Ganciclovir; Hodgkin Disease; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Renal Insufficiency; Secondary Prevention; Treatment Failure; Virus Activation | 2007 |
A model of human cytomegalovirus infection in severe combined immunodeficient mice.
Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay | 2007 |
Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Ribonucleosides; Sequence Alignment; Viral Proteins | 2008 |
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Protein Structure, Tertiary; Viral Proteins | 2008 |
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antiviral Agents; Base Sequence; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins; Virus Activation | 2008 |
Intravenous immunoglobulin as rescue therapy for BK virus nephropathy.
Topics: Antiviral Agents; BK Virus; Child, Preschool; Cidofovir; Creatinine; Cytosine; Ganciclovir; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Kidney; Kidney Transplantation; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2009 |
Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Male; Organophosphonates; Simplexvirus; Stem Cell Transplantation; Stomatitis; Treatment Outcome | 2009 |
Longitudinal analysis of human herpesvirus-8 DNA and antibodies in an Italian allogeneic stem cell transplant recipient.
Topics: Antibodies, Viral; Cidofovir; Cytosine; DNA, Viral; Encephalitis; Fatal Outcome; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Italy; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Organophosphonates; Stem Cell Transplantation; Transplantation, Homologous | 2011 |
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.
Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2012 |
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Viral; Eye; Female; Foscarnet; Ganciclovir; Humans; Organophosphonates; Plasma; Sequence Analysis, DNA | 2012 |
Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Pancreas Transplantation; Recurrence; Stomach; Treatment Outcome | 2012 |
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA | 2013 |
Generation and characterization of a GCV resistant HCMV UL97-mutation and a drug sensitive UL54-mutation.
Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutagenesis; Mutation, Missense; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins | 2013 |
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates | 2014 |
UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Organophosphonates; Viral Proteins | 2014 |
Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; High-Throughput Nucleotide Sequencing; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Organophosphonates; Pneumonia, Viral; Time Factors; Viral Proteins; Virus Replication | 2014 |
Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Cercopithecine; Macaca mulatta; Mice; Organophosphonates; Simplexvirus; Trifluridine; Vero Cells; Viral Plaque Assay | 2014 |
Identification of newly detected, drug-related HCMV UL97- and UL54-mutations using a modified plaque reduction assay.
Topics: Adult; Antiviral Agents; Cell Line; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Genotype; Humans; Infant; Male; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2015 |
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins | 2016 |
Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance.
Topics: Adolescent; Adult; Antiviral Agents; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Infant; Middle Aged; Mutation; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Genetic; Viral Proteins | 2016 |
Combination therapies using an intratympanic polymer gel delivery system in the guinea pig animal model: A safety study.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Drug Combinations; Drug Delivery Systems; Follow-Up Studies; Ganciclovir; Glucocorticoids; Guinea Pigs; Hearing Loss; Hydrogels; Injection, Intratympanic; Organophosphonates; Polyesters; Polyethylene Glycols; Polymers | 2016 |
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles | 2017 |
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Mutation; Organ Transplantation; Organophosphonates; Postoperative Complications; Real-Time Polymerase Chain Reaction; Retrospective Studies; Thailand; Young Adult | 2017 |
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
Topics: A549 Cells; Adenoviridae Infections; Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Cidofovir; Cricetinae; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Immunosuppression Therapy; Liver; Male; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunoglobulins; Immunoglobulins, Intravenous; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Postoperative Complications; Tissue Donors | 2017 |
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus.
Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication | 2018 |
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus.
Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides | 2019 |
Multidrug-resistant cytomegalovirus infection in a patient with granulomatosis with polyangiitis during immunosuppressive treatment.
Topics: Antiviral Agents; Cidofovir; Cyclophosphamide; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Middle Aged; Prednisone | 2020 |
In vitro co-infection by cytomegalovirus improves the antiviral activity of ganciclovir against human adenovirus.
Topics: A549 Cells; Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cell Line; Cidofovir; Coinfection; Cytomegalovirus; DNA, Viral; Ganciclovir; Humans; Inhibitory Concentration 50; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor) | 2020 |
A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.
Topics: Antiviral Agents; Betacoronavirus; Cidofovir; Coronavirus Infections; COVID-19; Dideoxynucleosides; Ganciclovir; Guanine; Nucleotides; Pandemics; Pneumonia, Viral; Prodrugs; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Stavudine; Valganciclovir | 2020 |
Outcomes of transplant recipients treated with cidofovir for resistant or refractory cytomegalovirus infection.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Retrospective Studies; Transplant Recipients | 2021 |
Opposite effects of cytomegalovirus UL54 exonuclease domain mutations on acyclovir and cidofovir susceptibility.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Ganciclovir; Mutation; Viral Proteins | 2021 |
Intra-host diversity of drug-resistant cytomegalovirus: A case report of cytomegalovirus infection after allogeneic hematopoietic cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Mutation; Phosphotransferases (Alcohol Group Acceptor) | 2022 |
Genotypic and Phenotypic Study of Antiviral Resistance Mutations in Refractory Cytomegalovirus Infection.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Humans; Mutation; Phenotype; Viral Proteins | 2022 |
Filociclovir is a potent inhibitor of human adenovirus F41.
Topics: Adenoviruses, Human; Antiviral Agents; Child; Cidofovir; Ganciclovir; Humans; Valganciclovir | 2022 |
In Vitro efficacy of cyclosporine a and various antiseptics and antiviral drugs on adenovirus genotype 8, a common cause of epidemic keratoconjunctivitis.
Topics: Adenoviridae; Adenoviridae Infections; Anti-Infective Agents, Local; Antiviral Agents; Chlorhexidine; Cidofovir; Cyclosporine; Ganciclovir; Genotype; Humans; Keratoconjunctivitis; Povidone-Iodine | 2023 |
Prevalence of cytomegalovirus antiviral drug resistance in transplant recipients.
Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Prevalence; Transplant Recipients; Viral Proteins | 2023 |