cidofovir anhydrous has been researched along with cytosine in 1167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (0.26) | 18.7374 |
| 1990's | 287 (24.59) | 18.2507 |
| 2000's | 573 (49.10) | 29.6817 |
| 2010's | 290 (24.85) | 24.3611 |
| 2020's | 14 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Bronson, JJ; De Boeck, H; Hitchcock, MJ; Ho, HT; Martin, JC; Woods, KL | 1 |
| Balzarini, J; De Clercq, E; Naesens, L; Neyts, J | 1 |
| Andrei, G; Cloes, JM; De Clercq, E; Piette, J; Rentier, B; Sadzot-Delvaux, C; Schols, D; Snoeck, R | 1 |
| Andrei, G; De Clercq, E; Desmyter, J; Goubau, P; Snoeck, R | 1 |
| Holy, A; Leonhardt, JA; Mead, JR; Morris, JL; Sidwell, RW; Smee, DF | 1 |
| Burns, P; Chatterjee, S; Kern, ER; Whitley, RJ | 1 |
| Field, HJ; Gibson, JS; Slater, JD | 1 |
| Araullo-Cruz, T; De Clercq, E; Gordon, YJ; Romanowski, E | 1 |
| Holý, A; Otová, B; Votruba, I | 1 |
| Kern, ER; Patel, P; Simecka, JW | 1 |
| Armani, R; Bergeron-Lynn, GL; Boscher, C; Capparelli, E; Connor, JD; De Clercq, E; Dolnak, DR; Munguia, D; Sherwood, C; Wiley, CA | 1 |
| Kern, ER | 2 |
| Hitchcock, MJ; Martin, JC | 1 |
| Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE | 1 |
| Bohm, R; Hitchcock, MJ; Huang, JL; Martin, JC; Soike, KF; Zhang, JY | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
| De Clercq, E; Maudgal, PC | 2 |
| De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R | 1 |
| Bruggeman, CA; de Clercq, E; Stals, FS | 1 |
| Cerný, J; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Sedivá, K; Veselý, J; Vlach, J; Votruba, I | 1 |
| Araullo-Cruz, T; De Clercq, E; Erzurum, S; Gordon, YJ; Romanowski, E; Seaberg, L; Tolman, R | 1 |
| Holý, A; Symerský, J | 1 |
| De Clercq, E | 16 |
| Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T | 1 |
| Datema, R; Yang, H | 1 |
| Bronson, JJ; Ferrara, LM; Ghazzouli, I; Hitchcock, MJ; Ho, HT; Kern, ER; Martin, JC; Soike, KF; Woods, KL | 1 |
| De Clercq, E; Holý, A | 1 |
| Bronson, JJ; De Boeck, H; Ghazzouli, I; Hitchcock, MJ; Ho, HT; Martin, JC; Woods, K | 1 |
| Kim, CU; Luh, BY; Martin, JC | 1 |
| Feng, JS; Fong, CK; Hsiung, GD; Li, SB; Lucia, HL; Yang, ZH | 1 |
| Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR | 1 |
| De Clercq, E; Holy, A; Rosenberg, I; Sakuma, T; Snoeck, R | 1 |
| Chatterjee, S; Gangopadhyay, NN; Whitley, RJ | 1 |
| Aspe, E; Ennis, RD; Guy, RH; Kennedy, JA; Lee, WA; Visor, GC | 1 |
| Nightingale, SL | 2 |
| Cundy, KC; Fisher, PE; Flaherty, J; Hitchcock, MJ; Jaffe, HS; Lalezari, JP; Lietman, PS; Petty, BG; Polis, MA; Wachsman, M | 1 |
| Andrei, G; Clumeck, N; De Clercq, E; De Wit, S; Poncin, M; Snoeck, R; Van Ranst, M | 1 |
| Cundy, K; Drew, WL; Fisher, PE; Flaherty, J; Glutzer, E; Hannigan, J; James, C; Lalezari, JP; Martin, JC; Miner, D | 1 |
| Arevalo, JF; Chavez de la Paz, E; De Clercq, E; Freeman, WR; Garcia, R; Kirsch, LS; Munguia, D | 1 |
| Cohen, J | 2 |
| Masur, H; Polis, MA | 1 |
| Aduma, P; Connelly, MC; Fridland, A; Srinivas, RV | 1 |
| Arevalo, JF; Chavez de la Paz, E; de Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D | 1 |
| Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF | 1 |
| Assil, KK; Bergeron-Lynn, G; Besen, G; De Clercq, E; Flores-Aguilar, M; Gangan, P; Kupperman, BD; Munguia, D; Pursley, M; Vuong, C | 1 |
| de Clercq, E; Fiten, P; Geboes, K; Janssens, J; Opdenakker, G; Rutgeerts, P; Snoeck, R; Van Cutsem, E; Van Ranst, M; Vantrappen, G | 1 |
| Baird, BF; Davey, RT; Falloon, J; Fisher, PE; Jaffe, HS; Kovacs, JA; Manischewitz, JF; Polis, MA; Spooner, KM; Walker, RE | 1 |
| De Clercq, E; Kaminsky, R; Zweygarth, E | 1 |
| Barkhimer, DB; Bischofberger, N; Chen, MS; Cundy, KC; Hitchcock, MJ; Kent, KM; Lacy, SA; Lee, WA; Li, ZH; Mendel, DB | 1 |
| Hamzeh, FM; Lee, FE; Lietman, PS; Moore, MR | 1 |
| Araullo-Cruz, T; Gordon, YJ; Romanowski, EG | 3 |
| De Clercq, E; Neyts, J | 6 |
| Allen, SJ; Chen, MS; Cherrington, JM; McKee, BH | 1 |
| Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G | 1 |
| Davidson, JM; Drew, WL; Fisher, PE; Glutzer, E; Jaffe, HS; Lalezari, JP; Miner, D; Owen, WF; Safrin, S | 1 |
| Bílá, V; Holý, A; Jelínek, R; Kren, V; Mejsnarová, B; Otová, B; Sladká, M | 1 |
| Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA | 1 |
| Connelly, MC; Fridland, A; Robbins, BL | 1 |
| Awan, AR; Field, HJ | 1 |
| Bruggeman, CA; de Clercq, E; Havennith, M; Stals, FS; Zeytinoglu, A | 1 |
| Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A | 1 |
| Field, HJ; Gilliam, SE | 1 |
| De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M | 1 |
| Bravo, FJ; Kern, ER; Kier, AB; Stanberry, LR; Vogt, PE | 1 |
| Andrei, G; Clumeck, N; De Clercq, E; Gerard, M; Sadzot-Delvaux, C; Snoeck, R; Tricot, G | 1 |
| Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA | 1 |
| Barkhimer, DB; Chen, MS; Mendel, DB | 1 |
| Cherrington, JM; Drew, WL; Hitchcock, MJ; Lalezari, JP; Miner, R | 1 |
| Franková, D; Holý, A; Otová, B; Zídek, A | 1 |
| Chen, MS; Huang, ES; Kim, C; Smith, JL; Xiong, X | 1 |
| Balzarini, J; De Clercq, E; Dvoráková, H; Holý, A; Naesens, L; Reymen, D | 1 |
| Cundy, KC; Hitchcock, MJ; Lee, WA; Lynch, G; Shaw, JP | 1 |
| Jabs, DA | 2 |
| Arevalo, JF; Azen, SP; Chavez de la Paz, E; Freeman, WR; Munguia, D; Rahhal, FM | 1 |
| Arevalo, JF; Azen, SP; Chavez de la Paz, E; Freeman, WR; Munguia, D; Rahhal, FM; Taskintuna, I | 1 |
| Freeman, WR | 1 |
| Flaherty, JF | 1 |
| Cundy, KC; Fisher, PE; Jaffe, HS; Lietman, PS; Pastelak, A; Petty, BG; Wachsman, M | 1 |
| Besen, G; Capparelli, EV; Connor, JD; el-Haig, W; Freeman, WR; Kim, JW | 1 |
| Danner, SA | 1 |
| Chatterjee, S; Lakeman, F; Nii, S; Whitley, RJ; Yamada, M; Yoshida, M | 1 |
| Balzarini, J; De Clercq, E; Naesens, L | 1 |
| De Clercq, E; Kodama, E; Shigeta, S; Suzuki, T | 1 |
| de Oliveira, CB; LaBree, L; McDonnell, PJ; Stevenson, D; Trousdale, MD | 1 |
| Drew, WL; Hitchcock, MJ; Jaffe, HS; Lalezari, JP; Stagg, RJ | 1 |
| Cundy, KC; Hitchcock, MJ; Lee, WA; Li, ZH | 1 |
| Bidgood, AM; Cundy, KC; Griffin, L; Lee, WA; Lynch, G; Shaw, JP | 1 |
| Cundy, KC; Lee, WA; Li, ZH | 1 |
| Bryson, HM; Lea, AP | 1 |
| Samuels, GJ; Visor, GC; Yuan, LC | 1 |
| DeClercq, E; Gordon, YJ; Maudgal, PC; Naesens, L; Veckeneer, M | 1 |
| Reusser, P | 1 |
| Andrei, G; De Clercq, E; Snoeck, R | 3 |
| Meinert, CL | 1 |
| Bosmans, E; Bron, D; De Clereq, E; Delforge, A; Lagneaux, L; Schols, D; Snoeck, R; Stryckmans, P | 1 |
| de Clercq, E; De Hauwere, B; Lutz, A; Maudgal, PC; Neyts, J | 1 |
| Schwartz, DM | 1 |
| Barnett, BB; Sidwell, RW; Smee, DF | 1 |
| Chen, MS; Cihlar, T | 1 |
| Araullo-Cruz, TP; Gordon, YJ; Johnson, YF; Kinchington, PR; Romanowski, EG | 1 |
| Cundy, KC; Eisenberg, EJ | 1 |
| Drew, WL; Holland, GN; Ives, DV; Jaffe, HS; Kramer, F; Kuppermann, BD; Lalezari, JP; Robinson, MR; Stagg, RJ; Youle, M | 1 |
| Andrei, G; De Clercq, E; Snoeck, R; Vandeputte, M | 1 |
| Chen, MS; Smith, JL; Xiong, X | 1 |
| Chen, MS; Cihlar, T; Mendel, DB; Moon, K | 1 |
| Hardy, WD | 1 |
| Kuppermann, BD | 1 |
| Lalezari, JP | 1 |
| Kuppermann, BD; Lalezari, JP | 1 |
| Cassady, KA; Whitley, RJ | 1 |
| Arevalo, JF; Chavez-de la Paz, E; De Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D; Rahhal, FM | 1 |
| Cunningham, ET | 2 |
| Eizuru, Y; Harada, K; Ihara, S; Isashiki, Y; Minamishima, Y | 1 |
| Ganem, D; Kedes, DH | 1 |
| Arevalo, JF; Banker, AS; De Clercq, E; Freeman, WR; Munguia, D; Rahhal, FM; Taskintuna, I | 1 |
| Davis, JL; Feuer, WJ; Freeman, WR; Leonard, RE; Taskintuna, I; Weinberg, DV | 1 |
| Friedberg, DN | 1 |
| Cherrington, JM; Freeman, WR; Fuller, MD; Jiles, RE; Smith, IL; Spector, SA | 1 |
| Jacobson, MA | 1 |
| Blick, G; Garton, T; Hopkins, U; LaGravinese, L | 1 |
| Okleberry, KM; Smee, DF; Warren, RP | 1 |
| Bruggeman, CA; Kloover, JS; Stals, FS; Vanagt, WY | 1 |
| Cundy, KC; Lee, WA; Lynch, G | 1 |
| Hosoya, K; Lee, VH | 1 |
| Connely, M; Fridland, A; Srinivas, RV | 1 |
| Banker, AS; Bergeron-Lynn, G; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Keefe, K; Munguia, D; Rao, NA; Taskintuna, I; Wiley, CA | 1 |
| Gazzard, BG; Morris-Jones, S; Nelson, M; Sadler, M | 1 |
| Beaufils, H; Deray, G; Dumitrescu, L; Vittecoq, D | 1 |
| Rockstroh, JK; Sauerbruch, T; Schliefer, K; Spengler, U | 1 |
| Arevalo, JF; Banker, AS; Berry, C; De Clercq, E; Freeman, WR; Ishimoto, B; Munguia, D; Ochabski, R; Rahhal, FM; Taskintuna, I | 1 |
| Meadows, KP; Pavia, AT; Rallis, TM; Tyring, SK | 1 |
| Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME | 1 |
| Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG | 1 |
| Katlama, C | 1 |
| Kravcik, S | 1 |
| Dahl, TC; Ennis, RD | 1 |
| Palau, LA; Pankey, GA; Tufty, GT | 1 |
| Boggs, J; Cheung, T; Corey, L; Drew, WL; Feinberg, J; Gathe, J; Jaffe, HS; Kessler, H; Kramer, F; Lalezari, J; Lee, S; McGuire, B; Safrin, S; Schacker, T | 1 |
| Cockerell, CJ; Goetz, D; Naylor, M; Sands, B; Zabawski, EJ | 1 |
| Vaghjimal, A | 1 |
| Pérez, JL | 1 |
| Arevalo, JF; Banker, AS; De Clercq, E; Freeman, WR; Mueller, AJ; Rahhal, FM; Rao, NA; Taskintuna, I; Wiley, CA | 1 |
| Luks-Golger, DB; Martinez, CM | 1 |
| Blick, G; Garton, T; Griegor, P; Hopkins, U; LaGravinese, L; Whiteside, M | 1 |
| De Clercq, E; Neyts, J; Pagano, JS; Raab-Traub, N; Sadler, R | 1 |
| Takahashi, K | 1 |
| Ai, E; Freeman, WR; Mueller, AJ; Powell, HC; Rahhal, FM; Smith, IL; Spector, SA; Taskintuna, I | 1 |
| Smith, CL | 1 |
| Baldanti, F; Biron, KK; Gerna, G | 1 |
| Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY | 1 |
| Pau, AK | 1 |
| De Clercq, E; Desloovere, C; Feenstra, L; Naesens, L; Snoeck, R; Van Ranst, M; Wellens, W | 1 |
| Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M | 1 |
| Chinn, R; Fisher, M; Gazzard, BG; Healy, J; Nelson, MR; Sadler, M | 1 |
| Akler, ME; Burman, WJ; Johnson, DW; Johnson, SC | 1 |
| Clark, NM; Greenson, JK; Hedderwick, SA; McGaughy, VR | 1 |
| Capparelli, EV; Cundy, KC; Freeman, WR; Rahhal, FM; Taskintuna, I | 1 |
| Behnsch, M; Bergmann, F; Grobusch, MP; Liekfeld, A; Schürmann, D | 1 |
| Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ | 1 |
| Freeman, WR; Karavellas, MP; Macdonald, JC; Morse, LS; Reed, JB; Torriani, FJ | 1 |
| Schleppy, CA; Tritten, JJ | 1 |
| Hammoud, Z; Parenti, DM; Simon, GL | 1 |
| Engler, RJ; Katial, RK; Myers, KW | 1 |
| Banker, AS; Bergeron-Lynn, G; De Clercq, E; Freeman, WR; Keefe, KS; Taskintuna, I | 2 |
| Cherrington, JM; Cihlar, T; Fuller, MD | 1 |
| De Clercq, E; De Dobbeleer, G; Noel, JC; Parent, D; Simonart, T; Snoeck, R; Van Vooren, JP | 1 |
| Andrei, G; De Clercq, E; Liekens, S; Neyts, J; Vandeputte, M | 1 |
| Kaufman, HE; Thompson, HW; Varnell, ED | 2 |
| Cinatl, J; Scholz, M; Vogel, JU | 1 |
| Gross, G | 1 |
| Hou, J; Major, EO | 1 |
| Cherrington, JM; Cihlar, T; Fuller, MD; Mulato, AS | 1 |
| Dunn, JP; Enger, C; Forman, M; Jabs, DA | 1 |
| Cundy, KC; Hitchcock, MJ; Lacy, SA; Lee, WA; Tellier, P | 1 |
| Don, PC; Kaufmann, M; Lateef, F; Weinberg, JM; White, SM | 1 |
| Aissa, N; Carquin, J; Dewilde, A; Freymuth, F; Houhou-Fidouh, N; Mazeron, MC; Scieux, C; Thouvenot, D | 1 |
| Bidgood, AM; Cundy, KC; Eisenberg, EJ; Krishnamurty, K; Lynch, GR | 1 |
| Dunn, JP; Enger, C; Forman, M; Hubbard, L; Jabs, DA | 1 |
| Freeman, WR; Garcia, CR; Torriani, FJ | 1 |
| Althaus, C; Hudde, T; Kersten, A; Pascha, G; Schweykart, N; Sundmacher, R | 1 |
| Diaz-Mitoma, F; Hughes, A; Jaffe, HS; McGuire, B; Rudy, J; Sacks, SL; Safrin, S; Shafran, SD; Sibbald, RG; Trottier, S | 1 |
| Mucci, M | 1 |
| Cockerell, CJ; Zabawski, EJ | 1 |
| Delfraissy, JF; Dussaix, E; Gasnault, J; Goujard, C; Karaterki, A; Lannuzel, A; Marchadier, E; Pierre Ferey, M; Taoufik, Y | 1 |
| Cherrington, JM; Drew, WL; Fuller, MD; Lalezari, JP; Lamy, PD; Miner, R; Nuessle, S | 1 |
| Avila, CP; Cheng, L; Freeman, WR; Keefe, KS; Macdonald, JC; Rao, NA | 1 |
| Fan-Havard, P; Kendle, JB | 1 |
| Bolton, SG; Dunn, JP; Jabs, DA; Palestine, AG | 1 |
| Badiaga, S; Brouqui, P; Parola, P; Zandotti, C | 1 |
| De Clercq, E; Noel, JC; Simonart, T; Snoeck, R | 1 |
| Barditch-Crovo, P; Cundy, KC; Jaffe, HS; Lietman, PS; Petty, BG; Redpath, M; Ruby, A | 1 |
| Bartels, SP; Gordon, YJ; Romanowski, EG | 1 |
| Aweeka, FT; Brody, SR; Cundy, KC; Gambertoglio, JG; Humphreys, MH; Schoenfeld, P | 1 |
| Azen, SP; Freeman, WR; Karavellas, MP; Macdonald, JC; Plummer, DJ; Shufelt, CL; Torriani, FJ | 1 |
| Cazorla, C; Dupon, M; Dutronc, H; Lacut, JY; Neau, D; Ragnaud, JM; Renaud-Rougier, MB; Viallard, JE | 1 |
| Engstrom, RE; Holland, GN; Lin, AP | 1 |
| Bedard, J; Bowlin, T; Chan, L; Drach, J; Huffman, J; Lis, M; May, S; Rando, R; Sidwell, R; Tryphonas, L | 1 |
| Lee, WA; Oliyai, R; Visor, GC; Yuan, LC | 1 |
| Antinori, A; De Luca, A; Fantoni, M; Tartaglione, T | 1 |
| Mortimer, CB; Salit, IE; Tseng, AL | 1 |
| Cundy, KC | 1 |
| Cheung, TW; Teich, SA | 1 |
| Cherrington, J; Holtzer, C; Jacobson, MA; Safrin, S; Stanley, H; Wilson, S | 1 |
| Freymuth, F; Gluckman, E; Morinet, F; Ribaud, P; Scieux, C | 1 |
| Bretlau, P; Buchwald, C; Gerstoft, J; Lindeberg, H; Petersen, BL | 1 |
| Maeder, P; Meylan, PR; Sahli, R; Tagan, MC; Vuadens, P | 1 |
| Gangemi, JD; Johnson, JA | 2 |
| Afouna, MI; DeClercq, E; El-Shattawy, HH; Ghanem, AH; Higuchi, WI; Kern, ER; Mehta, SC | 1 |
| Barbeau, D; Bedard, J; Bowlin, TL; May, S; Rando, RF; Yuen, L | 1 |
| Skiest, DJ | 1 |
| Andrei, G; De Clercq, E; Delvenne, P; Piette, J; Snoeck, R | 2 |
| Davies, EG; Harper, J; Lacey, K; Thrasher, A | 1 |
| Balzarini, J; de Clercq, E; de Vries, E; Franssen, FF; Holý, A; Naesens, L; Overdulve, JP; Smeijsters, LJ | 1 |
| Buchanan, J; Davis, LJ | 1 |
| Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD | 1 |
| Canzano, JC; Morse, LS; Wendel, RT | 1 |
| Brambilla, AM; Castagna, A; Cinque, P; Lazzarin, A; Moioli, MC; Novati, R; Terreni, MR | 1 |
| Cihlar, T; Fuller, MD; Lin, DC; Mendel, DB; Pritchard, JB; Sweet, DH | 1 |
| Abbed, K; Boue, F; Delfraissy, JF; Dussaix, E; Gasnault, J; Goujard, C; Kousignian, P; Taoufik, Y | 1 |
| Drew, WL; Lalezari, JP | 1 |
| Noble, S; Plosker, GL | 1 |
| Ambati, J; Angerame, MC; Robinson, MR; Wynne, KB | 1 |
| Adriani, B; Beretta, R; Cargnel, A; Fasolo, MM; Orlando, G; Signori, R; Zanchetta, N | 1 |
| Duncan, NO; Kang, DR; Kearns, DB; Magit, AE; Pransky, SM | 1 |
| Gümbel, HO; Rockstroh, JK; Schliefer, K; Spengler, U | 1 |
| Althaus, C; Best, J; Kersten, AJ; Sundmacher, R | 1 |
| Hoy, J | 1 |
| Cherrington, J; Jaffe, HS; Safrin, S | 1 |
| Besselmann, M; Happe, S; Husstedt, IW; Matheja, P; Reichelt, D; Rickert, CH; Schuierer, G | 1 |
| Arimilli, MN; Cundy, KC; Jones, RJ; Lee, WA; Oliyai, R; Shaw, JP; Sueoka-Lennen, CM | 1 |
| Cosyns, JP; Goffin, E; Jadoul, M; Marot, JC; Moreau, M; Vandercam, B | 1 |
| Keating, MR | 1 |
| Bossens, M; De Clercq, E; Muller, C; Noel, JC; Snoeck, R | 1 |
| Bray, M; Huggins, JW; Kefauver, D; Martinez, M; Smee, DF; Thompson, E | 1 |
| Cochereau, I; Diraison, MC; Doan, S; Guvenisik, N; Hoang-Xuan, T; Mousalatti, H; Ren, L | 1 |
| Berenguer, J; Mallolas, J | 1 |
| Chocarro Martinez, A; Garcia Garcia, I; Gonzalez Lopez, A | 1 |
| Au Eong, KG; Beatty, S; Charles, SJ | 1 |
| Ainsworth, J; Bainbridge, JW; Pinching, AJ; Raina, J; Shah, SM | 1 |
| Blaheta, RA; Cinatl, J; Doerr, HW; Gümbel, HO; Kotchetkov, R; Scholz, M; Vogel, JU; Weimer, E | 1 |
| Bolger, G; Bousquet, C; Cordingley, M; Garneau, M; Kibler, P; Lapeyre, N; Rhéaume, M | 1 |
| Gordon, YJ; Romanowski, EG | 2 |
| Brink, NS; Groves, RW; Kapur, N; Preiser, W; Snoeck, R | 1 |
| Emery, VC | 2 |
| Cihlar, T; Ho, ES; Lin, DC; Mendel, DB | 1 |
| Aoki, K; Goto, M; Inagawa, W; Ishiko, H; Itoh, N; Nagamoto, Y; Nakajima, H; Ohno, S; Shimada, Y; Uchio, E | 1 |
| Bourboulia, D; Bower, M; Fife, K; Gazzard, B; Gill, J; Nelson, M | 1 |
| Garweg, JG | 1 |
| Delfraissy, JF; Frau, E; Gasnault, J; Goujard, C; Labetoulle, M; Offret, H | 1 |
| Hashemiyoon, R; Hawrych, A; Wilson, WR | 1 |
| Agut, H; Debré, P; Gautheret-Dejean, A; Grenot, P; Huraux, JM; Manichanh, C | 1 |
| Bergmann, F; Grobusch, MP; Schürmann, D; Suttorp, N; Temmesfeld-Wollbrück, B | 1 |
| Cordingley, MG; De Marte, J; Duan, J; Fleet, TL; Paris, W; Roopchand, D | 1 |
| Hengge, UR; Tietze, G | 1 |
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| Andrei, G; De Schutter, T; Duraffour, S; Matthys, P; Mitera, T; Snoeck, R; Topalis, D; van den Oord, J | 1 |
| Brock, E; Doern, C; Pugni, L; Ronchi, A; Sánchez, PJ | 1 |
| Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD | 1 |
| Gattringer, KB; Jäger, W; Kraff, S; Thalhammer, F; Vossen, MG | 1 |
| Anglada Martínez, H; Carcelero San Martín, E; Castro Rebollo, P; Soy Muner, D | 1 |
| Ader, F; Barraco, F; Billaud, G; Chidiac, C; Detrait, M; Ducastelle-Leprêtre, S; Ferry, T; Gilis, L; Labussière-Wallet, H; Michallet, M; Morisset, S; Nicolini, FE; Salles, G; Sobh, M; Tedone, N; Thomas, X | 1 |
| Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D | 1 |
| Boivin, G; Piret, J | 1 |
| Gregg, K; Hakki, M; Kaul, DR | 1 |
| Dufier, JL; Laccourreye, O; Orssaud, C; Roche, O; Roux, A; Sors, H; Wermert, D | 1 |
| Cleary, A; McMahon, CJ; Watson, R | 1 |
| Andrei, G; Balzarini, J; Krečmerová, M; Masojídková, M; Pohl, R; Snoeck, R | 1 |
| Bachy, V; Grasso, M; Lawson, G; Remacle, M; Van Der Vorst, S | 1 |
| Hanna, I; Ingraham, L; Li, M; Parker, S; Pelis, RM; Renfro, JL; Vapurcuyan, A | 1 |
| Chou, S; Ercolani, RJ; Lefterova, MI; Pinsky, BA; Sahoo, MK; Strasfeld, LM | 1 |
| Balogh, KK; Christensen, ND; Cladel, NM; Hu, J | 1 |
| Damon, IK; Foster, S; Gates, I; Lanier, ER; Li, Y; Olson, VA; Smith, SK; Trost, LC | 1 |
| Cianciolo, R; Derebail, VK; Lachiewicz, AM; Miller, MB | 1 |
| Beckley, I; de Ridder, D; Van der Aa, F | 1 |
| Chambers, HE; Florescu, DF; Florescu, MC; Keck, MA; Mercer, DF; Morris, MC; Qiu, F | 1 |
| Alaibac, M; Peserico, A; Piaserico, S; Sandini, E | 1 |
| Alcamo, AM; Grimley, MS; Mo, JQ; O'Brien, MM; Pinchasik, DE | 1 |
| Franz, E; Hsu, S; Nguyen, HP; Stiegel, KR; Tyring, SK | 1 |
| Feltkamp, MC; Fouchier, RA; Hajdarbegovic, E; Jones, T; Muhlemann, B; van Boheemen, S | 1 |
| Cuny, JF; Foissac, M; Goehringer, F; Lekaditi, M; May, T; Ranaivo, IM; Schmutz, JL | 1 |
| Dutton, P; Fiander, A; Griffiths, G; Hibbitts, S; Hurt, CN; Jones, S; Madden, T; Man, S; Naik, R; Nordin, AJ; Powell, N; Tristram, A | 1 |
| Mahner, S; Wölber, L | 1 |
| Casanova, JL; Kilic, SS; Puel, A | 1 |
| Dagley, A; Downs, B; Hagloch, J; Smee, DF; Tarbet, EB | 1 |
| Black, DH; Brush, LA; Eberle, R; Maxwell, LK; Mccormack, KA; Payton, ME; Ritchey, JW; Wright, G | 1 |
| Exner, TE; Möller, HM; Victora, A | 1 |
| DeVos, JM; Gaber, AO; Gaber, LW; Knight, RJ; Kuten, SA; Patel, SJ | 1 |
| Bonvicini, F; Bua, G; Gallinella, G; Manaresi, E | 2 |
| Andrei, G; De Schutter, T; Snoeck, R; Topalis, D | 1 |
| Leach, KL; Piotrowski, M; Wang, R; Zhang, H; Zhang, X | 1 |
| Buller, RM; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B | 1 |
| Endo, K; Kondo, S; Murono, S; Nakanishi, Y; Tsuji, A; Wakisaka, N; Yoshida, H; Yoshizaki, T | 1 |
| de Alencastro, RB; de Souza, FR; França, TC; Gonçalves, AS; Guimarães, AP; Oliveira, AA; Ramalho, TC | 1 |
| Ball, LM; Bredius, RG; Bresters, D; Jol-van der Zijde, CM; Kollen, WJ; Lankester, AC; Lugthart, G; Oomen, MA; Schilham, MW; Smiers, FJ; van Tol, MJ; Vermont, CL | 1 |
| Chemaly, RF; Hosing, C; Lahoti, A; Saunders, IM; Trevino, C; Westmoreland, M | 1 |
| Athas, DM; Bruminhent, J; Flomenberg, P; Hess, BD | 1 |
| Gijsbers, S; Liekens, S; Noppen, S; Presta, M; Ronca, R; Sienaert, R; Tobia, C | 1 |
| Braverman, RS; Caruso Brown, AE; Cohen, MN; Giller, R; Levin, MJ; Rooney, JF; Tong, S | 1 |
| Foster, SA; Godin, SJ; Keilholz, L; Khouri, J; Long, J; Rose, ML; Trost, LC | 1 |
| Ahn, JS; Ahn, SY; Jang, HC; Jang, MO; Jung, SH; Kang, SJ; Kim, HJ; Kim, JY; Kim, YK; Lee, JJ; Lee, SS; Yang, DH | 1 |
| Campo, F; DE Vincentiis, M; Fusconi, M; Gallo, A; Grasso, M; Greco, A; Pagliuca, G; Remacle, M; Turchetta, R | 1 |
| Burger-Calderon, R; Jeffers-Francis, LK; Webster-Cyriaque, J | 1 |
| Arenas-Villafranca, J; de Troya, M; Del Boz, J; Escudero-Santos, I; Fernández-Morano, T; Padilla España, L | 1 |
| Hong, DJ; Jhun, BW; Kim, K; Kim, SJ; Park, SB | 1 |
| Bilius, V; Pasauliene, R; Rageliene, L; Rascon, J; Verkauskas, G; Zubka, V | 1 |
| Andronova, VL; Deryabin, PG; Galegov, GA; Jasko, MV; Kukhanova, MK; Skoblov, YS | 1 |
| Fechner, H; Kurreck, J; Pozzuto, T; Röger, C | 1 |
| Kovarik, C; Moore, E | 1 |
| Iapadre, G; Lasorella, S; Mareri, A; Maresca, M; Nigro, G; Tambucci, R | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Sampaio, KL | 1 |
| Bryant, A; Kaushik, S; Lawrie, TA; Nordin, A; Pepas, L | 1 |
| Allard, A; Ljungman, P; Mattsson, J; Sparrelid, E; Swartling, L; Törlen, J | 1 |
| Acartürk, F; Özkul, A; Tuğcu-Demiröz, F | 1 |
| Toth, K; Wold, WS | 1 |
| Judd, BE; Ledbetter, EC; Mohammed, HO; Pennington, MR; Spertus, CB; Van de Walle, GR | 1 |
| Akst, L; Best, SR; Bishop, JA; Hillel, A; Karatayli-Ozgursoy, S | 1 |
| Albariño, C; Dyall, J; Flint, M; Foster, S; Hensley, LE; Lanier, ER; McMullan, LK; Nichol, ST; Olinger, GG; Sethna, P; Spiropoulou, CF | 1 |
| Buck, CB; Knight, SA; Nakamaru-Ogiso, E; Tsang, SH; Wang, R; You, J | 1 |
| Baizhumanova, AS; Kim, HT | 1 |
| Zeitels, SM | 1 |
| Aitken, SL; Chemaly, RF; Ghantoji, SS; Jones, RB; Kontoyiannis, DP; Tam, VH; Zhou, J | 1 |
| Beato, M; de Lucas, R; Feito, M; Mayor, A; Ramos, E; Santesteban, R | 1 |
| Loignon, M; Toma, E | 1 |
| Ader, F; Barraco, F; Ducastelle-Leprêtre, S; Gilis, L; Labussiere-Wallet, H; Lebras, L; Michallet, M; Nicolini, FE; Philippe, M; Ranchon, F; Rioufol, C; Salles, G; Schwiertz, V; Thomas, X; Vantard, N; Wattel, E | 1 |
| Bryant, A; Chakrabarti, M; Kaushik, S; Lawrie, TA; Nordin, A; Pepas, L | 1 |
| Álvarez-Gallego, M; Arribas, JR; Beato, MJ; Bernardino, JI; Díaz-Almirón, M; Feíto, M; Feltes, R; González-García, J; Herranz, P; Pérez-Molina, JA; Sendagorta, E; Yllescas, M | 1 |
| Hilgendorf, C; Jansen, K; Masereeuw, R; Nieskens, TT; Peters, JG; Röring, M; Schreurs, MJ; Smits, N; van der Made, TK; Wilmer, MJ; Woestenenk, R | 1 |
| Andrei, G; Balzarini, J; De Schutter, T; El Amri, C; Krečmerová, M; Naesens, L; Nogueira, TC; Snoeck, R; Topalis, D | 1 |
| Endo, K; Kondo, S; Murono, S; Nakanishi, Y; Tsuji, A; Wakisaka, N; Yoshizaki, T | 1 |
| Kawabata, H; Kondo, T; Sakurada, M; Takaori-Kondo, A; Umeda, M; Yamashita, K | 1 |
| Behrendt, V; Ellrichmann, G; Gold, R; Grunwald, C; Lukas, C; Schlottmann, R | 1 |
| Fort, MW; Ledbetter, EC; Pennington, MR; Van de Walle, GR | 1 |
| Astor, BC; Djamali, A; Mandelbrot, D; Mohamed, M; Muth, B; Panzer, SE; Parajuli, S; Zhong, W | 1 |
| Adam, J; Bayar, MA; Chargari, C; Deutsch, E; Haie-Meder, C; Lanoy, E; Laporte, M; Levy, A; Magné, N; Mazeron, R; Mondini, M; Pautier, P; Soria, JC; Varga, A; Vassal, G | 1 |
| Chou, S; Ercolani, RJ; Lanier, ER | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Hofmann, J; Imrich, E; Jahn, G; Sampaio, KL | 1 |
| Choo, DI; Nassar, M; Pordal, A; Quimby, C; Sidell, D; Ward, JA | 1 |
| Epstein, JB; Gharapetian, S; Lill, M; Rejali, AR; Tzachanis, D; Zabner, R | 1 |
| Araki, R; Espinoza, JL; Kuzushima, K; Nakao, S; Nishimura, R; Okumura, H; Takamatsu, H; Yachie, A; Yoshida, T | 1 |
| Andrei, G; Mertens, B; Naesens, L; Nogueira, T; Snoeck, R; Stranska, R | 1 |
| Agut, H; Bonnafous, P; Gautheret-Dejean, A | 1 |
| Eiz-Vesper, B; Heim, A; Maecker-Kolhoff, B; Schultze-Florey, RE; Schwerk, N; Tischer, S | 1 |
| Ahmed, MM; Connor, MP; Howard, NS; Lospinoso, J; Maturo, SC; O'Connor, P; Palazzolo, M; Thompson, ME | 1 |
| Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S | 1 |
| Kajon, AE; Lynch, JP | 1 |
| Barshak, MB; Durand, ML; Foster, CS; Kim, IK; Mali, JO; Scott, NL; Stryjewski, TP; Tobin, EH; Young, LH | 1 |
| Berger, A; Christopeit, M; Hauf, E; Hentrich, M; Heussel, CP; Kalkreuth, J; Klein, M; Kochanek, M; Lehners, N; Mayer, K; Penack, O; Rieger, C; Schalk, E; Silling, G; Vehreschild, M; von Lilienfeld-Toal, M; Weber, T; Wolf, HH | 1 |
| Choi, Y; Jeong, J; Jun, JB; Jung, J; Kim, H; Lee, SH | 1 |
| Henrickson, SE; Treat, JR | 1 |
| Hayden, RT; Ison, MG | 1 |
| Jeong, I; Kim, JH; Kim, S; Kwon, OJ; Kwon, SJ; Lee, M; Na, MJ; Park, HW; Son, JW; Yoon, YS | 1 |
| Figueras Suriol, A; Pi Sala, N; Ramió Montero, E | 1 |
| Drašar, P; Kopečná, M; Kotora, M; Macháček, M; Prchalová, E; Štěpánek, P; Vávrová, K | 2 |
| Brigger, M; Drejet, S; Halum, S; Parker, NP; Skopelja, E | 1 |
| Krecmerova, M | 1 |
| Battistelli, S; Benedetti, S; Catalani, S; Galati, R; Nuvoli, B; Palma, F | 1 |
| Meacham, RK; Thompson, JW | 1 |
| Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY | 1 |
| Rosen, T | 1 |
| Coroneo, MT; Ip, MH | 1 |
| Andronova, VL; Charushin, VN; Denisova, AO; Galegov, GA; Kayushin, AL; Kharitonova, MI; Konstantinova, ID; Kotovskaya, SK; Miroshnikov, AI | 1 |
| Brothers, AW; Englund, JA; Vora, SB | 1 |
| Aktaş, Y; Bilensoy, E; Sandler, N; Varan, C; Wickström, H | 1 |
| Bruminhent, J; Rotjanapan, P; Watcharananan, SP | 1 |
| Arora, R; Garg, A; Gupta, M; Gupta, N; Singh, M | 1 |
| Bryant, D; Fiander, AN; Hibbitts, S; Hurt, CN; Jones, SEF; Powell, N; Tristram, AJ | 1 |
| Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B | 1 |
| Achdout, H; Erez, N; Israeli, O; Israely, T; Lustig, S; Melamed, S; Paran, N; Politi, B; Tamir, H; Waner, T | 1 |
| Kaltashov, IA; Xu, S | 1 |
| Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L | 1 |
| Bibee, K; Cuda, JD; Erdag, G; Girardi, N; Loss, MJ; Orens, JB; Prono, MD; Rangwala, S; Smith, SDB; Toptan, T | 1 |
| Andrei, G; Brisse, E; Imbrechts, M; Matthys, P; Mitera, T; Snoeck, R; Vandenhaute, J; Wouters, CH | 1 |
| Grassi, G; Mazzaglia, A; Neri, G; Pennisi, R; Piperno, A; Pizzo, MM; Scala, A; Sciortino, MT; Sortino, G; Zagami, R; Zhu, Y | 1 |
| Bossens, M; De Maertelaer, V; Evrard, B; Frankenne, F; Hubert, P; Jost, M; Simon, P; Snoeck, R; Van Pachterbeke, C | 1 |
| Azar, MM; Hibbert, KA; Lane, RJ; Shepard, JO | 1 |
| Joffe, M; Tang, JW; Wagner, SD | 1 |
| Cheng, WS; Foster, JH; Krance, R; Martinez, C; Nguyen, NY | 1 |
| Darragh, RK; Parent, JJ; Serrano, RM | 1 |
| Krüger, W; Neumann, T; Schmidt, CA; Schneidewind, L | 1 |
| Green, M; Lopez, SMC; Michaels, MG | 1 |
| DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P | 1 |
| Hawley, J; Lappin, M; Powell, C; Rekers, W; Veir, J; Zirofsky, D | 1 |
| Bae, A; Bambara, RA; Chamberlain, JM; Dewhurst, S; Lanier, R; Sethna, P; Sortino, K | 1 |
| Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG | 1 |
| Armbrust, KR; Koozekanani, D; Santilli, CM | 1 |
| Bergón-Sendín, M; Carretero-López, F; Nieto-Benito, LM; Parra-Blanco, V; Pulido-Pérez, A; Romero-Jiménez, R; Rosell-Díaz, Á; Suárez-Fernández, R | 1 |
| Cottrell, ML; Dunn, JA; Guzman, BB; Schauer, AP; Sykes, C | 1 |
| Abi Aad, Y; Alonso, CD; Avery, RK; Cardozo, C; Cornely, OA; Epstein, DJ; Garcia-Vidal, C; Ho, SA; Koehler, P; Maertens, J; Mehta Steinke, S; Neofytos, D; Papanicolaou, GA; Scheid, C; Slavin, M; Stern, A; Yong, MK | 1 |
| Kerman, A; Napolitano, L; Schroedl, L; Shea, CR | 1 |
| Sassine, J; Siegrist, EA | 1 |
| Gündoğdu, Y; Gür, H; Kartı, SS; Koşan, B; Okuturlar, Y; Uzay, A; Yetiş, T | 1 |
| Boan, P; O'Brien, A | 1 |
| Bodnar, M; Borowczak, J; Burduk, P; Czech, J; Mackiewicz-Nartowicz, H; Rutkiewicz, P; Sinkiewicz, A; Solarz, P; Szylberg, Ł; Zwierz, A | 1 |
| Bernardino, JI; Busto-Leis, JM; Díaz-Menéndez, M; Escudero-Tornero, R; Gutiérrez Arroyo, A; Herranz Pinto, P; Roces Álvarez, P; Sendagorta Cudos, E; Servera-Negre, G; Sobral-Costas, TG | 1 |
| Bernstein, DI; Cardin, RD; Chadderdon, AM; Doherty, MK; Domagala, JM; Gan, X; Harden, EA; Harteg, CC; Hartline, CB; Hutchings, KM; James, SH; Keith, KA; Lipka, E; Prichard, MN; Reyna, DM; Simon, ES; Spencer, JF; Tollefson, AE; Toth, K; White, AD; Wold, WSM | 1 |
| Abbara, A; Armstrong-James, D; Awad, Z; Campbell, V; Chand, M; Chiu, C; Cooke, G; Davies, C; Davies, EP; Davies, F; Dhanji, S; ElHaddad, A; Gilchrist, M; Gómez, CHM; Kumar, V; Mora-Peris, B; Muir, D; Osman, S; Peters, J; Rampling, T; Randell, P; Rimmer, S; Smart, C; Stafford, A; Sun, K; Swaine, T; Waddington, CS; Warrell, CE | 1 |
| Bei, ZC; Cao, B; Song, Y; Wang, B; Wang, H; Xu, L; Zhang, D; Zhao, L | 1 |
183 review(s) available for cidofovir anhydrous and cytosine
| Article | Year |
|---|---|
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1991 |
Chemotherapy of the acquired immune deficiency syndrome (AIDS): acyclic nucleoside phosphonate analogues.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Organophosphonates; Organophosphorus Compounds | 1991 |
Broad-spectrum anti-DNA virus and anti-retrovirus activity of phosphonylmethoxyalkylpurines and -pyrimidines.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; DNA, Viral; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Virus Replication | 1991 |
Therapeutic potential of phosphonylmethoxyalkylpurines and -pyrimidines as antiviral agents.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Purines; Pyrimidines; Retroviridae Infections; Virus Diseases | 1990 |
Biochemical pharmacology of acyclic nucleotide analogues.
Topics: Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; HIV; Humans; Nucleotides; Organophosphonates; Organophosphorus Compounds | 1990 |
Promising new treatments for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections, Intralesional; Organophosphonates; Organophosphorus Compounds | 1995 |
Antivirals for the treatment of herpesvirus infections.
Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1993 |
Management of cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1995 |
The potential of acyclic nucleoside phosphonates as broad-spectrum antiviral agents.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Stereoisomerism | 1995 |
A preclinical and clinical overview of the nucleotide-based antiviral agent cidofovir (HPMPC).
Topics: Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds | 1996 |
Cidofovir.
Topics: Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds | 1996 |
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine | 1996 |
New therapies for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Administration Routes; Drug Therapy, Combination; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1996 |
Management strategies for patients with cytomegalovirus retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Interactions; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds | 1997 |
Therapeutic options for resistant cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Recurrence; Thionucleotides | 1997 |
Cidofovir: a new therapy for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents | 1997 |
Clinical experience with cidofovir in the treatment of cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytomegalovirus Retinitis; Cytosine; Humans; Kidney; Organophosphonates; Organophosphorus Compounds | 1997 |
New therapeutic approaches to the alphaherpesvirus infections.
Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine | 1997 |
Cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Retinitis | 1997 |
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Management of CMV retinitis in HIV infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Prodrugs; Prospective Studies; Recurrence | 1997 |
Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.
Topics: Antiviral Agents; Cidofovir; Codon; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Viral Structural Proteins | 1997 |
Cidofovir use in acyclovir-resistant herpes infection.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus | 1997 |
[Recent advances in antiviral drugs--antiviral agents to HCMV, HHV-6, and HHV-7].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Purines; Thymidine Kinase | 1998 |
Local therapy for cytomegalovirus retinitis.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1998 |
Acyclic nucleoside phosphonates in the chemotherapy of DNA virus and retrovirus infections.
Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytosine; DNA Virus Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections | 1997 |
Treatment of cytomegalovirus diseases.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Therapy of human papillomavirus infection and associated epithelial tumors.
Topics: Aminoquinolines; Antineoplastic Agents; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Humans; Imiquimod; Interferon Inducers; Interferons; Laser Therapy; Neoplasms, Glandular and Epithelial; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Tumor Virus Infections; Vaccines, Synthetic | 1997 |
Cidofovir in the treatment of cytomegalovirus (CMV) retinitis.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds | 1998 |
Topical and intralesional cidofovir: a review of pharmacology and therapeutic effects.
Topics: Administration, Cutaneous; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Herpesviridae Infections; Humans; Injections, Intralesional; Injections, Intravenous; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Sarcoma, Kaposi; Skin Diseases, Viral; Skin Neoplasms; Tumor Virus Infections | 1998 |
Cidofovir in the treatment of cytomegaloviral disease.
Topics: Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Interactions; Humans; Organophosphonates; Organophosphorus Compounds | 1998 |
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir.
Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Interactions; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Insufficiency | 1999 |
Cytomegalovirus infection in patients with HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART).
Topics: Antiviral Agents; Biomarkers; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Diagnosis, Differential; Foscarnet; Ganciclovir; Herpesviridae; Humans; Incidence; Organophosphonates; Organophosphorus Compounds; Risk Factors | 1999 |
Cytomegalovirus: disease syndromes and treatment.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System Diseases; Chorioretinitis; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds; Pneumonia; Sexually Transmitted Diseases, Viral | 1999 |
Cidofovir: a review of its use in cytomegalovirus retinitis in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Humans; In Vitro Techniques; Organophosphonates; Organophosphorus Compounds | 1999 |
Management of CMV infections in HIV-infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Cidofovir. Review of current and potential clinical uses.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
[Cidofovir (vistide) in therapy of progressive multifocal leukoencephalopathy in AIDS. Review of the literature and report of 2 cases].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Brain; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Organophosphorus Compounds; Tomography, Emission-Computed | 1999 |
Antiviral agents for non-human immunodeficiency virus infections.
Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir | 1999 |
Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retinal Detachment | 1999 |
Cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds | 1998 |
Uveitis in HIV positive patients.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; HIV Seropositivity; Humans; Organophosphonates; Organophosphorus Compounds; Rifabutin; Sarcoidosis; Syphilis; Tuberculosis; Uveitis | 2000 |
[Anterior segment involvement in HIV-related eye disease after the commencement of highly active antiretroviral therapy (HAART)].
Topics: AIDS-Related Opportunistic Infections; Animals; Anti-HIV Agents; Antibiotics, Antitubercular; Cidofovir; Cytosine; Diagnosis, Differential; Drug Therapy, Combination; Eye Diseases; Humans; Organophosphonates; Organophosphorus Compounds; Rifabutin; Uveitis | 2000 |
Cytomegalovirus infection following stem cell transplantation.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency | 1999 |
What's new in human papillomavirus infection.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Child; Cidofovir; Cimetidine; Cytosine; Histamine H2 Antagonists; Humans; Hypnosis; Imiquimod; Keratolytic Agents; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Podophyllotoxin; Recurrence; Risk Factors; Warts | 2000 |
Successful treatment of juvenile laryngeal papillomatosis-related multicystic lung disease with cidofovir: case report and review of the literature.
Topics: Adult; Antiviral Agents; Biopsy; Cidofovir; Cystic Adenomatoid Malformation of Lung, Congenital; Cytosine; Diagnosis, Differential; DNA, Viral; Female; Humans; Laryngeal Neoplasms; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Papillomavirus Infections; Tomography, X-Ray Computed; Tumor Virus Infections | 2000 |
Progressive multifocal leukoencephalopathy and idiopathic CD4+lymphocytopenia: a case report and review of reported cases.
Topics: Antiviral Agents; Cidofovir; Cytosine; Fatal Outcome; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; T-Lymphocytopenia, Idiopathic CD4-Positive | 2000 |
Therapeutic developments in cytomegalovirus retinitis.
Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir | 2000 |
Prophylaxis against herpesvirus infections in transplant recipients.
Topics: Antibiotic Prophylaxis; Antiviral Agents; Cidofovir; Cytosine; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpesviridae Infections; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Purines; Transplantation | 2001 |
A review of topical and intralesional cidofovir.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA Virus Infections; DNA Viruses; Humans; Injections, Intralesional; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral | 2000 |
[Ocular complications after treatment with intravenous cidofovir for cytomegalovirus retinitis].
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Injections, Intravenous; Male; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior | 2001 |
Progress in understanding cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Forecasting; Foscarnet; Ganciclovir; Humans; Incidence; Organophosphonates; Organophosphorus Compounds | 2001 |
Use of cidofovir in progressive multifocal leukoencephalopathy.
Topics: Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Cidofovir in the treatment of HPV-associated lesions.
Topics: Administration, Topical; Antiviral Agents; Apoptosis; Cell Division; Cidofovir; Cytosine; Female; Humans; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Tumor Virus Infections | 2001 |
Economic evaluation of systemic treatments for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Economics, Pharmaceutical; Foscarnet; Ganciclovir; Humans; Models, Economic; Organophosphonates; Organophosphorus Compounds; Switzerland; Treatment Failure | 2001 |
[Prospects for therapy and prevention of adenovirus keratoconjunctivitis].
Topics: Adenovirus Infections, Human; Adolescent; Adrenal Cortex Hormones; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cyclosporine; Cytosine; Humans; Immunosuppressive Agents; Interferons; Keratitis; Keratoconjunctivitis, Infectious; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Recurrence; Time Factors | 2001 |
Cytomegalovirus infection: the point in 2001.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Monitoring; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Population Surveillance; Predictive Value of Tests; Prevalence; Risk Factors; Valganciclovir | 2001 |
Recent developments in herpesvirus therapy.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine | 2001 |
A clinical, molecular and cytogenetic study of 12 cases of human herpesvirus 8 associated primary effusion lymphoma in HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bleomycin; Chromosome Aberrations; Cidofovir; Cyclophosphamide; Cytosine; Doxorubicin; Drug Therapy, Combination; Etoposide; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Immunophenotyping; Interferon-alpha; Karyotyping; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Immunoblastic; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prednisone; Prognosis; Remission Induction; Survival Analysis; Vincristine; Vindesine; Viral Load | 2001 |
Cytomegalovirus drug resistance and clinical implications.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Incidence; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2001 |
Therapy for recurrent respiratory papillomatosis.
Topics: Cidofovir; Cytosine; Humans; Interferons; Laryngeal Neoplasms; Lung Neoplasms; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Photochemotherapy; Vocal Cords | 2002 |
Understanding the threat of smallpox.
Topics: Bioterrorism; Cidofovir; Cytosine; Diagnosis, Differential; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States | 2002 |
Management of CMV disease in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Encephalitis, Viral; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Cidofovir in the treatment of poxvirus infections.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; Immunocompromised Host; Injections, Intraperitoneal; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Poxviridae; Poxviridae Infections | 2002 |
[Perspectives for the treatment and prevention of herpes simplex infections].
Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Famciclovir; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Imiquimod; Interferon Inducers; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine | 2002 |
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2002 |
The role of growth factors, angiogenic enzymes and apoptosis in neovascularization and tumor growth-collected publications.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cidofovir; Cyclohexanes; Cytosine; Disease Models, Animal; Fibroblast Growth Factor 2; Growth Substances; Hemangioma; Humans; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Organophosphonates; Organophosphorus Compounds; Rats; Sesquiterpenes; Thymidine Phosphorylase; Tumor Virus Infections | 2002 |
[Progressive multifocal leukoencephalopathy (PML) in chronic lymphatic leukemia (CLL). Review of the literature and case report].
Topics: Antiviral Agents; Brain; Cidofovir; Cytosine; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukoencephalopathy, Progressive Multifocal; Long-Term Care; Magnetic Resonance Imaging; Male; Middle Aged; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds | 2002 |
Cidofovir in the therapy and short-term prophylaxis of poxvirus infections.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Poxviridae Infections; Prodrugs | 2002 |
[Drugs against human cytomegalovirus].
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drugs, Investigational; Female; Foscarnet; Ganciclovir; Global Health; Humans; Infectious Disease Transmission, Vertical; Naphthalenesulfonates; Organophosphonates; Organophosphorus Compounds; Pregnancy; Pregnancy Complications, Infectious; Thionucleotides; Valacyclovir; Valganciclovir; Valine | 2002 |
Progressive multifocal leukoencephalopathy after stem cell transplantation, unsuccessfully treated with cidofovir.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brain; Cidofovir; Combined Modality Therapy; Cytosine; Fatal Outcome; HIV Seronegativity; Humans; Immunocompromised Host; JC Virus; Leukoencephalopathy, Progressive Multifocal; Lymphoma, Mantle-Cell; Magnetic Resonance Imaging; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Treatment Failure | 2002 |
Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients.
Topics: Cidofovir; Cytomegalovirus Infections; Cytosine; DNA Virus Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds | 2002 |
Herpes simplex virus resistance to antiviral drugs.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Herpes Simplex; Humans; Immunocompromised Host; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins; Virus Replication | 2003 |
Observations on the early results of treatment of recurrent respiratory papillomatosis using cidofovir.
Topics: Antineoplastic Agents; Child, Preschool; Cidofovir; Cytosine; Female; Glottis; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laser Therapy; Male; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Time Factors; Treatment Outcome | 2002 |
Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; History, 20th Century; Humans; Organophosphonates; Organophosphorus Compounds; Poxviridae Infections; Smallpox; Time Factors; Vaccinia | 2003 |
In vitro activity of potential anti-poxvirus agents.
Topics: Adenine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Humans; Mice; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Virus Replication | 2003 |
A review of compounds exhibiting anti-orthopoxvirus activity in animal models.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Humans; Mice; Mice, SCID; Nucleosides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Poxviridae Infections; Rabbits; Smallpox; Thiosemicarbazones | 2003 |
Progressive vaccinia.
Topics: Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Methisazone; Organophosphonates; Organophosphorus Compounds; Ribavirin; Vaccination; Vaccinia | 2003 |
[Therapeutic possibilities for polyomavirus infections in renal transplantation].
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Humans; JC Virus; Kidney Transplantation; Nephritis, Interstitial; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Virus Replication | 2003 |
Topical cidofovir for the treatment of dermatologic conditions: verruca, condyloma, intraepithelial neoplasia, herpes simplex and its potential use in smallpox.
Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Carcinoma in Situ; Carcinoma, Squamous Cell; Cidofovir; Condylomata Acuminata; Cytosine; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Infectious; Skin Neoplasms; Smallpox; Warts | 2003 |
Management of acyclovir-resistant herpes simplex virus.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine | 2003 |
[Ocular complications of the virostatic drug cidofovir].
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Eye Diseases; Humans; Infusions, Intravenous; Injections; Leukoencephalopathy, Progressive Multifocal; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior; Vitreous Body | 2003 |
[BK virus-associated nephropathy].
Topics: Adult; Age Factors; Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; Female; Graft Rejection; Humans; Infant; Kidney Diseases; Kidney Transplantation; Male; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Pregnancy; Time Factors; Tumor Virus Infections | 2003 |
Pediatric molluscum contagiosum: optimal treatment strategies.
Topics: Aminoquinolines; Antipruritics; Antiviral Agents; Cantharidin; Child; Child, Preschool; Chronic Disease; Cidofovir; Cryosurgery; Curettage; Cytosine; Female; Garlic; Humans; Imiquimod; Incidence; Male; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Retinoids | 2003 |
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunotherapy; Lymphocyte Depletion; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning | 2003 |
Polyomavirus BK.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Humans; Immunocompromised Host; Kidney Diseases; Kidney Transplantation; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Tumor Virus Infections | 2003 |
Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections.
Topics: Adenine; Animals; Cidofovir; Cytosine; DNA Virus Infections; DNA Viruses; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Retroviridae Infections; Reverse Transcriptase Inhibitors; Tenofovir | 2003 |
Established and potential strategies against papillomavirus infections.
Topics: Aminoquinolines; Antimetabolites; Antiviral Agents; Cidofovir; Cytosine; Drug Design; Fluorouracil; Humans; Imiquimod; Indoles; Interferon Inducers; Interferons; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Podophyllin; Viral Vaccines | 2004 |
Smallpox: clinical features, prevention, and management.
Topics: Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Female; Humans; Infant; Male; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine | 2004 |
The pharmacokinetics of antiviral therapy in paediatric patients.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases | 2003 |
Antiviral prophylaxis of smallpox.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; Vaccination | 2004 |
Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Virus Replication | 2004 |
Treatment of adenovirus infections in the immunocompromised host.
Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Prognosis; Ribavirin; Severity of Illness Index; Transplantation Immunology; Treatment Outcome; Vidarabine | 2004 |
Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA Virus Infections; Drug Resistance, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Tenofovir | 2003 |
Current diagnostic and management trends for recurrent respiratory papillomatosis.
Topics: Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Humans; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Respiratory Tract Neoplasms | 2004 |
Invasive adenoviral infection in a recipient of unrelated bone marrow transplantation: Problems with diagnostic PCR.
Topics: Adenovirus Infections, Human; Adolescent; Antiviral Agents; Cidofovir; Cytosine; Diagnostic Errors; Female; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Polymerase Chain Reaction; Postoperative Complications; Transplantation, Homologous; Viremia | 2005 |
[Smallpox].
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Diagnosis, Differential; Humans; Organophosphonates; Polymerase Chain Reaction; Smallpox; Smallpox Vaccine; Vaccines, Attenuated; Variola virus | 2004 |
Drug-induced renal failure in the ICU.
Topics: Acute Kidney Injury; Adenine; Amphotericin B; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Calcineurin Inhibitors; Cidofovir; Cyclooxygenase Inhibitors; Cytosine; Foscarnet; Hemodynamics; Humans; Hydroxyethyl Starch Derivatives; Immunoglobulins, Intravenous; Intensive Care Units; Kidney; Organophosphonates; Tacrolimus | 2004 |
Development in lipid drugs.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cowpox virus; Cytosine; Dendritic Cells; Glycyrrhizic Acid; HIV-1; Humans; Lipids; Major Histocompatibility Complex; Melanoma; Organophosphonates; Orthopoxvirus; Peptides; Severe acute respiratory syndrome-related coronavirus; T-Lymphocytes | 2005 |
[Antiherpetic therapy].
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine | 2005 |
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Topics: Adult; Antineoplastic Agents; Child; Cidofovir; Clinical Trials as Topic; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Respiratory Tract Neoplasms | 2005 |
[Current therapeutic options for recurrent respiratory papillomatosis].
Topics: Adult; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Combinations; Follow-Up Studies; Humans; Indoles; Interferons; Laser Therapy; Neoplasm Recurrence, Local; Organophosphonates; Otorhinolaryngologic Neoplasms; Papilloma; Treatment Outcome | 2005 |
Recurrent respiratory papillomatosis: pathogenesis to treatment.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Human papillomavirus 11; Human papillomavirus 6; Humans; Indoles; Interferon-alpha; Laryngeal Neoplasms; Laser Therapy; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Papillomavirus Infections; Viral Vaccines | 2005 |
BK virus nephritis after renal transplantation.
Topics: Antibodies, Viral; Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Graft Survival; Humans; Immunity, Cellular; Immunosuppressive Agents; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Nephritis; Organophosphonates; Polyomavirus Infections; Prevalence; Risk Factors; Treatment Outcome; Tumor Virus Infections; Viremia | 2006 |
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Schedule; Epstein-Barr Virus Infections; Famciclovir; Foscarnet; Herpes Zoster; Herpesviridae Infections; Humans; Immunocompromised Host; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Trifluridine; Valacyclovir; Valine | 2006 |
Transbronchial needle injection: a systematic review of a new diagnostic and therapeutic paradigm.
Topics: Bronchoscopy; Catheterization; Cidofovir; Cytosine; Equipment Design; Humans; Injections; Lung Diseases; Lung Neoplasms; Organophosphonates; Papilloma; Respiratory Tract Neoplasms; Secondary Prevention; Solitary Pulmonary Nodule; Thoracic Neoplasms | 2006 |
[Treatment of HHV-6 and HHV-7 infections].
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunoglobulins; Lymphocyte Transfusion; Organophosphonates; Roseolovirus Infections | 2006 |
Antiviral therapy for adenovirus infections.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Immunocompromised Host; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Organophosphonates; Ribavirin | 2006 |
Polyomavirus-associated nephropathy: update on antiviral strategies.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Organophosphonates; Polyomavirus; Polyomavirus Infections; Quinolones | 2006 |
Papillomavirus and treatment.
Topics: Antiviral Agents; Carcinoma; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Female; Humans; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Uterine Cervical Neoplasms; Viral Vaccines; Warts | 2006 |
[Advances in the study of nucleoside antiviral drugs].
Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Cytosine; Dioxolanes; Humans; Molecular Structure; Nucleosides; Organophosphonates; Purine Nucleosides; Tenofovir | 2006 |
Treatment of adenovirus disease in stem cell transplant recipients with cidofovir.
Topics: Adenovirus Infections, Human; Adult; Aged; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Colitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Hepatitis, Viral, Human; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Male; Nephritis; Organophosphonates; Transplantation, Homologous; Viral Load | 2007 |
[Neuropathology of progressive multifocal leukoencephalopathy].
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; Cidofovir; Cytarabine; Cytosine; Demyelinating Diseases; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Oligodendroglia; Organophosphonates | 2007 |
[Progressive multifocal leukoencephalopathy--epidemiology, clinical pictures, diagnosis and therapy].
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Biomarkers; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Humans; Japan; JC Virus; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Prognosis; Tomography, X-Ray Computed | 2007 |
Adenovirus infection after allogeneic stem cell transplantation.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Risk Factors; Transplantation, Homologous | 2007 |
Management of recurrent oral herpes simplex infections.
Topics: Acyclovir; Antiviral Agents; Bell Palsy; Cidofovir; Cytosine; Erythema Multiforme; Herpes Labialis; Humans; Immunocompromised Host; Organophosphonates; Secondary Prevention; Sunscreening Agents; Time Factors; Valacyclovir; Valine | 2007 |
[Mechanism of drug-resistance in human cytomegalovirus].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2007 |
Treatment of congenital cytomegalovirus: where are we now?
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Humans; Infant, Newborn; Organophosphonates; Pregnancy; Valganciclovir | 2007 |
Antiviral agents for the treatment of recurrent respiratory papillomatosis: a systematic review of the English-language literature.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Injections, Intralesional; Neoplasm Recurrence, Local; Organophosphonates; Otorhinolaryngologic Neoplasms; Papilloma; Randomized Controlled Trials as Topic; Treatment Outcome | 2007 |
Can zinc be an adjuvant therapy for juvenile onset recurrent respiratory papillomatosis?
Topics: Adolescent; Antiviral Agents; Chemotherapy, Adjuvant; Child, Preschool; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Male; Organophosphonates; Papilloma; Zinc | 2007 |
Cidofovir: to use or not to use?
Topics: Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Humans; Injections, Intralesional; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Respiratory Tract Neoplasms | 2008 |
Cowpox virus infection: an emerging health threat.
Topics: Animals; Antiviral Agents; Cats; Cidofovir; Communicable Diseases, Emerging; Cowpox; Cowpox virus; Cytosine; Humans; Organophosphonates; Zoonoses | 2008 |
The discovery of antiviral agents: ten different compounds, ten different stories.
Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases | 2008 |
[Polyoma virus in transplant recipients].
Topics: Antiviral Agents; Cidofovir; Cytosine; Decision Trees; Humans; Immunosuppression Therapy; Kidney Transplantation; Organophosphonates; Polyomavirus; Polyomavirus Infections; Postoperative Complications; Risk Factors | 2008 |
Side-effects of cidofovir in the treatment of recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Animals; Antineoplastic Agents; Child; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2008 |
Scientific and clinical aspects of the use of cidofovir in recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Papillomavirus Infections; Respiratory Tract Neoplasms | 2008 |
Immunocompromised hosts: perspectives in the treatment and prophylaxis of cytomegalovirus disease in solid-organ transplant recipients.
Topics: Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Transplantation; Valganciclovir | 2008 |
Regulation of cancer progression by inhibition of angiogenesis and induction of apoptosis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cidofovir; Cytosine; Enzyme Inhibitors; Humans; Organophosphonates; Prognosis; Thymidine Phosphorylase | 2008 |
Progress in the discovery of compounds inhibiting orthopoxviruses in animal models.
Topics: Adenine; Animals; Antiviral Agents; Benzamides; Cidofovir; Cytosine; Disease Models, Animal; Drug Discovery; Humans; Isoindoles; Organophosphonates; Orthopoxvirus; Prodrugs | 2008 |
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir | 2008 |
Anti-HIV drugs for cancer therapeutics: back to the future?
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cytosine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; Neoplasms; Organophosphonates; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine | 2009 |
Low-dose cidofovir for the treatment of polyomavirus-associated nephropathy: two case reports and review of the literature.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2008 |
Antiviral treatment of cytomegalovirus infection and resistant strains.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Thionucleotides; Valganciclovir | 2009 |
Progressive multifocal leukoencephalopathy, a review and an extended report of five patients with different immune compromised states.
Topics: Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoxazoles; Leflunomide; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates | 2009 |
Cidofovir: clinical experience and future perspectives on an acyclic nucleoside phosphonate analog of cytosine in the treatment of refractory and premalignant HPV-associated anal lesions.
Topics: Antiviral Agents; Anus Neoplasms; Cidofovir; Cytosine; Humans; Organophosphonates; Papillomaviridae; Precancerous Conditions; Tumor Virus Infections | 2009 |
The management of condyloma acuminata in the pediatric population.
Topics: Adjuvants, Immunologic; Alphapapillomavirus; Aminoquinolines; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cimetidine; Condylomata Acuminata; Cryotherapy; Cytosine; Dermatologic Surgical Procedures; Female; Histamine H2 Antagonists; Humans; Imiquimod; Keratolytic Agents; Laser Therapy; Lasers, Dye; Lasers, Gas; Male; Organophosphonates; Papillomavirus Infections; Podophyllotoxin; Skin; Treatment Outcome | 2009 |
Treatment of polyomavirus infection in kidney transplant recipients: a systematic review.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cohort Studies; Creatinine; Cytosine; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Organophosphonates; Polyomavirus Infections; Randomized Controlled Trials as Topic; Reoperation; Survival Rate; Treatment Failure; Tumor Virus Infections; Viremia | 2010 |
Adjuvant antiviral therapy for recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Airway Obstruction; Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Humans; Organophosphonates; Papilloma; Recurrence; Respiratory Tract Neoplasms | 2010 |
Use of cidofovir for the treatment of HIV-negative human herpes virus-8-associated primary effusion lymphoma.
Topics: Antiviral Agents; Cidofovir; Cytosine; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Injections; Lymphoma, Primary Effusion; Organophosphonates | 2010 |
Five molecules we would take to a remote island.
Topics: Benzamides; Cidofovir; Colchicine; Cytosine; Humans; Imatinib Mesylate; Organophosphonates; Piperazines; Pyrimidines; Tacrolimus; Vaccines, Synthetic | 2010 |
Antiviral drug resistance of human cytomegalovirus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genome, Viral; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, DNA | 2010 |
The search for new therapies for human cytomegalovirus infections.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication | 2011 |
The BK virus in renal transplant recipients-review of pathogenesis, diagnosis, and treatment.
Topics: Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Polyomavirus Infections; Reoperation; Treatment Failure | 2011 |
Novel treatment of atypical human papillomavirus-associated epithelial hyperplasia with cidofovir.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Anus Neoplasms; Cidofovir; Cytosine; Epithelium; Fatal Outcome; HIV Infections; Humans; Male; Middle Aged; Molecular Structure; Mouth Diseases; Mouth Mucosa; Organophosphonates; Papillomavirus Infections | 2011 |
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Guanosine; Hepatitis B; HIV Infections; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Tenofovir | 2011 |
Deciphering the clinical impact of acute human herpesvirus 6 (HHV-6) infections.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Immunity, Cellular; Infant; Organophosphonates; Roseolovirus Infections; Viral Load; Virus Latency | 2011 |
Adenovirus.
Topics: Adenoviridae; Adenoviridae Infections; Adult; Age Factors; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Organophosphonates; Serotyping; Severity of Illness Index | 2011 |
Application of kinase bypass strategies to nucleoside antivirals.
Topics: Adenine; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; History, 20th Century; History, 21st Century; Humans; Nucleosides; Nucleotides; Organophosphonates; Phosphotransferases; Tenofovir | 2011 |
Intravesicular cidofovir for the treatment of polyomavirus-associated hemorrhagic cystitis.
Topics: Administration, Intravesical; Antiviral Agents; Cidofovir; Cystitis; Cytosine; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections | 2012 |
Human papillomavirus-related genital disease in the immunocompromised host: Part II.
Topics: Adjuvants, Immunologic; Alphapapillomavirus; Aminoquinolines; Antineoplastic Agents, Phytogenic; Antiviral Agents; Anus Neoplasms; Buschke-Lowenstein Tumor; Catechin; Caustics; Cidofovir; Condylomata Acuminata; Counseling; Cryotherapy; Cytosine; Female; Humans; Imiquimod; Immunocompromised Host; Male; Ointments; Organophosphonates; Papillomavirus Infections; Penile Neoplasms; Podophyllotoxin; Precancerous Conditions; Treatment Outcome; Trichloroacetic Acid; Vaginal Neoplasms; Vulvar Neoplasms; Warts | 2012 |
Treatment options for anal intraepithelial neoplasia and evidence for their effectiveness.
Topics: Adult; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cidofovir; Comorbidity; Cytosine; Female; Fluorouracil; Global Health; HIV Infections; Homosexuality, Male; Humans; Imiquimod; Incidence; Male; Organophosphonates; Papillomavirus Infections; Precancerous Conditions; Trichloroacetic Acid | 2012 |
[Treatment of anogenital warts with topical cidofovir].
Topics: Administration, Topical; Adult; Aminoquinolines; Antiviral Agents; Anus Diseases; Child; Cidofovir; Combined Modality Therapy; Condylomata Acuminata; Cryotherapy; Cytosine; Disease Susceptibility; Drug Evaluation; Drug Resistance, Viral; Electrocoagulation; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Imiquimod; Immunocompetence; Male; Organophosphonates; Podophyllotoxin; Remission Induction; Retrospective Studies; Young Adult | 2013 |
Adjuvant antiviral therapy for recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Airway Obstruction; Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Humans; Organophosphonates; Papilloma; Randomized Controlled Trials as Topic; Recurrence; Respiratory Tract Neoplasms | 2012 |
Systematic review of intralesional cidofovir dosing regimens in the treatment of recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Injections, Intralesional; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Treatment Outcome | 2013 |
The Holý Trinity: the acyclic nucleoside phosphonates.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Nucleosides; Organophosphonates; Prodrugs; Tenofovir; Virus Diseases | 2013 |
Intralesional cidofovir as adjuvant for the successful management of aggressive respiratory papillomatosis in an infant.
Topics: Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Risk Assessment; Severity of Illness Index; Time Factors; Treatment Outcome | 2013 |
[Non-antibiotic anti-infectious treatments in urology].
Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir | 2013 |
BK virus encephalitis: case report, review of the literature, and description of a novel treatment modality.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Encephalitis; Humans; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2013 |
Neonatal adenoviral infection: a seventeen year experience and review of the literature.
Topics: Adenoviridae; Adenoviridae Infections; Age Factors; Antiviral Agents; Body Temperature; Cidofovir; Cohort Studies; Cough; Cytosine; Diarrhea; Fatigue; Female; Gastrointestinal Hemorrhage; Hepatomegaly; Humans; Hypotension; Hypoxia; Immunoglobulins, Intravenous; Infant, Newborn; Intensive Care Units, Neonatal; Irritable Mood; Male; Muscle Hypotonia; Organophosphonates; Pancytopenia; Polymerase Chain Reaction; Respiratory Sounds; Retrospective Studies; Ribavirin; Splenomegaly; Tachypnea; Vomiting | 2014 |
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates | 2014 |
Cutaneous viral infections in organ transplant patients.
Topics: Acitretin; Administration, Cutaneous; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Dermatologic Agents; Hair Diseases; Herpes Simplex; Herpes Zoster; Humans; Ichthyosis; Imiquimod; Immunocompromised Host; Immunosuppressive Agents; Incidence; Italy; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Skin Diseases, Viral; Transplant Recipients; Warts | 2014 |
Treatment of molluscum contagiosum in adult, pediatric, and immunodeficient populations.
Topics: Adjuvants, Immunologic; Adult; Aminoquinolines; Antiviral Agents; Cantharidin; Child; Child, Preschool; Cidofovir; Cryotherapy; Curettage; Cytosine; Enzyme Inhibitors; Humans; Imiquimod; Immunocompromised Host; Infant; Infant, Newborn; Interferon-alpha; Molluscum Contagiosum; Organophosphonates; Sexually Transmitted Diseases, Viral | 2014 |
Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cidofovir; Cytosine; Humans; Neoplasms; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Polyomavirus; Polyomavirus Infections; Tumor Suppressor Protein p53 | 2015 |
Recurrent respiratory papillomatosis by HPV: review of the literature and update on the use of cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections | 2014 |
Anti-viral therapy for congenital cytomegalovirus infection: pharmacokinetics, efficacy and side effects.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompetence; Organophosphonates; Treatment Outcome | 2016 |
Medical interventions for high-grade vulval intraepithelial neoplasia.
Topics: Administration, Topical; Adult; Aminoquinolines; Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Female; Humans; Imiquimod; Indoles; Organophosphonates; Randomized Controlled Trials as Topic; Vulvar Neoplasms | 2015 |
Treatment options for progressive multifocal leukoencephalopathy in HIV-infected persons: current status and future directions.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Coinfection; Cytarabine; Cytosine; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Leukoencephalopathy, Progressive Multifocal; Mefloquine; Mianserin; Mirtazapine; Organophosphonates; Ritanserin; Serotonin Antagonists | 2016 |
Medical and surgical interventions for the treatment of usual-type vulval intraepithelial neoplasia.
Topics: Adult; Aminoquinolines; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Disease Progression; Female; Humans; Imiquimod; Indoles; Laser Therapy; Neoplasm Recurrence, Local; Organophosphonates; Photochemotherapy; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome; Vulvar Neoplasms | 2016 |
Successful treatment with intravesical cidofovir for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: A case report and a review of the literature.
Topics: Adenoviridae; Administration, Intravesical; Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Middle Aged; Organophosphonates; Transplantation, Homologous | 2016 |
Human Herpesviruses 6A, 6B, and 7.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunocompromised Host; Organophosphonates; Roseolovirus Infections; Transplant Recipients; Virus Latency | 2016 |
Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.
Topics: Adenoviridae; Adenoviridae Infections; Adenovirus Infections, Human; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Military Personnel; Organophosphonates; Prospective Studies; Respiratory Tract Infections; Serogroup; Viral Vaccines | 2016 |
Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Community-Acquired Infections; Cytosine; Germany; Hand Hygiene; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Influenza, Human; Lung; Masks; Medical Oncology; Metapneumovirus; Neoplasms; Neuraminidase; Nucleic Acid Amplification Techniques; Organophosphonates; Oseltamivir; Paramyxoviridae Infections; Patient Isolation; Pneumonia, Viral; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Tomography, X-Ray Computed; Virus Diseases | 2016 |
Adenovirus.
Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Diagnostic Tests, Routine; Disease Susceptibility; Drug Monitoring; Humans; Immunocompromised Host; Organophosphonates | 2016 |
Treatment of Adenoviral Acute Respiratory Distress Syndrome Using Cidofovir With Extracorporeal Membrane Oxygenation.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Extracorporeal Membrane Oxygenation; Female; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Pneumonia, Viral; Radiography; Respiratory Distress Syndrome; Severity of Illness Index; Treatment Outcome; Young Adult | 2017 |
A Systematic Review.
Topics: Adult; Angiogenesis Inhibitors; Antiviral Agents; Bevacizumab; Cidofovir; Cytosine; Humans; Injections, Intralesional; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Treatment Outcome | 2017 |
Amino Acid Ester Prodrugs of Nucleoside and Nucleotide Antivirals.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; Humans; Nucleosides; Nucleotides; Organophosphonates; Prodrugs | 2017 |
Treatment of human polyomavirus-7-associated rash and pruritus with topical cidofovir in a lung transplant patient: Case report and literature review.
Topics: Administration, Topical; Adult; Aged; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Exanthema; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Lung Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Pruritus; Transplant Recipients; Tumor Virus Infections | 2018 |
Comparison of intravenous or intravesical cidofovir in the treatment of BK polyomavirus-associated hemorrhagic cystitis following adult allogeneic stem cell transplantation-A systematic review.
Topics: Administration, Intravenous; Administration, Intravesical; Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections; Randomized Controlled Trials as Topic; Treatment Outcome; Tumor Virus Infections; Viral Load | 2018 |
Adenovirus infection in pediatric transplant recipients: are effective antiviral agents coming our way?
Topics: Adenoviridae Infections; Antiviral Agents; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Pediatrics; Transplant Recipients | 2018 |
BILATERAL UVEITIS AND HYPOTONY FOLLOWING TREATMENT WITH TOPICAL CIDOFOVIR.
Topics: AIDS-Related Opportunistic Infections; Choroidal Effusions; Cidofovir; Cytosine; Humans; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Uveitis; Uveitis, Anterior | 2023 |
Antivirals With Activity Against Mpox: A Clinically Oriented Review.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Monkeypox virus; Mpox (monkeypox); Organophosphonates | 2023 |
Use of cidofovir in a patient with severe mpox and uncontrolled HIV infection.
Topics: Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Male; Middle Aged; Mpox (monkeypox); Organophosphonates; State Medicine | 2023 |
64 trial(s) available for cidofovir anhydrous and cytosine
| Article | Year |
|---|---|
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatine; Cytomegalovirus Infections; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Semen; Virus Shedding | 1995 |
Phase I/II study of intravitreal cidofovir for the treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Tolerance; Female; Fundus Oculi; Humans; Injections; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Survival Analysis; Vitreous Body | 1995 |
Intravitreal cidofovir (HPMPC) treatment of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Retina; Uveitis; Vitreous Body | 1995 |
Susceptibility of human cytomegalovirus to cidofovir is unchanged after limited in vivo exposure to various regimens of drug.
Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 1996 |
Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects.
Topics: Adolescent; Adult; Antiviral Agents; Biological Availability; Cidofovir; Cytosine; Double-Blind Method; Drug Administration Routes; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Zidovudine | 1996 |
Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Visual Acuity | 1997 |
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Administration Schedule; Female; Fluid Therapy; Humans; Kidney Diseases; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Renal Agents; Visual Acuity | 1997 |
Anterior nongranulomatous uveitis after intravitreal HPMPC (cidofovir) for the treatment of cytomegalovirus retinitis. Analysis and prevention.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Glucocorticoids; Granuloma; Humans; Incidence; Injections; Iritis; Mydriatics; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Uricosuric Agents; Vitreous Body | 1997 |
A randomized, double-blind, placebo-controlled trial of cidofovir gel for the treatment of acyclovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Double-Blind Method; Drug Resistance, Microbial; Female; Foscarnet; Gels; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells | 1997 |
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraocular Pressure; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Recurrence; Renal Agents; Risk Factors; Visual Acuity | 1998 |
A multicenter phase I/II dose escalation study of single-dose cidofovir gel for treatment of recurrent genital herpes.
Topics: Adult; Aged; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gels; Herpes Genitalis; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Clinical pharmacokinetics of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine in human immunodeficiency virus-infected patients.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Biological Availability; Cidofovir; Cytosine; Female; HIV Infections; Humans; Injections, Intravenous; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prodrugs | 1999 |
Phase I study of combination therapy with intravenous cidofovir and oral ganciclovir for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Ganciclovir; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1999 |
Cidofovir, a new approach for the treatment of cervix intraepithelial neoplasia grade III (CIN III).
Topics: Adult; Antiviral Agents; Biopsy; Cervix Uteri; Cidofovir; Conization; Cytosine; Female; Humans; Immunohistochemistry; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2000 |
Intralesional cidofovir for recurrent laryngeal papillomas: preliminary report.
Topics: Adult; Antiviral Agents; Cidofovir; Clinical Protocols; Cytosine; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Recurrence; Retreatment; Treatment Outcome | 2000 |
Long-term follow-up of patients with AIDS treated with parenteral cidofovir for cytomegalovirus retinitis: the HPMPC Peripheral Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clin
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Morbidity; Organophosphonates; Organophosphorus Compounds; Time Factors; Treatment Outcome; Vision, Ocular | 2000 |
Clinical update on 10 children treated with intralesional cidofovir injections for severe recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Male; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Prospective Studies; Respiratory Tract Neoplasms; Treatment Outcome | 2000 |
Cidofovir added to HAART improves virological and clinical outcome in AIDS-associated progressive multifocal leukoencephalopathy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cerebrospinal Fluid; Cidofovir; Cytosine; DNA, Viral; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Seropositivity; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Proteinuria; RNA, Viral; Treatment Outcome | 2000 |
The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Double-Blind Method; Drug Evaluation; Drug Implants; Female; Ganciclovir; Humans; Infusions, Parenteral; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Survival Rate; Treatment Outcome; Uveitis; Visual Acuity; Vitreous Hemorrhage | 2001 |
Early diagnosis of adenovirus infection and treatment with cidofovir after bone marrow transplantation in children.
Topics: Adenovirus Infections, Human; Antiviral Agents; Bone Marrow Transplantation; Cell Nucleus; Child; Child, Preschool; Cidofovir; Cytosine; Digestive System; Epithelium; Female; Humans; Immunohistochemistry; Male; Organophosphonates; Organophosphorus Compounds; Time Factors; Treatment Outcome | 2001 |
SOCA research group stops enrollment. Studies of the Ocular Complications of AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Infusions, Intravenous; Kidney; Organophosphonates; Organophosphorus Compounds | 1996 |
NDA filed to treat refractory herpes.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Recurrence; United States; United States Food and Drug Administration | 1997 |
Update on treatment of CMV retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Eye; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic | 1995 |
Opportunistic infection highlights from the 35th ICAAC.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia | 1995 |
Cidofovir added to highly active antiretroviral therapy in AIDS-associated progressive multifocal leukoencephalopathy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds | 2001 |
Efficacy and tolerability of topical 1% cidofovir cream for the treatment of external anogenital warts in HIV-infected persons.
Topics: Administration, Cutaneous; Adult; Antiviral Agents; Anus Diseases; Cidofovir; Cytosine; Female; Female Urogenital Diseases; HIV Infections; Humans; Male; Male Urogenital Diseases; Organophosphonates; Organophosphorus Compounds; Patient Satisfaction; Pilot Projects; Single-Blind Method; Treatment Outcome; Tumor Virus Infections; Warts | 2001 |
Topical cidofovir for severe cutaneous human papillomavirus and molluscum contagiosum infections in patients with HIV/AIDS. A pilot study.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytosine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Pilot Projects; Recurrence; Severity of Illness Index; Skin Diseases, Viral; Treatment Outcome; Tumor Virus Infections | 2000 |
Phase II double-blind, placebo-controlled study of the safety and efficacy of cidofovir topical gel for the treatment of patients with human papillomavirus infection.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Risk Factors; Treatment Outcome; Tumor Virus Infections | 2001 |
Potent anti-retroviral therapy with or without cidofovir for AIDS-associated progressive multifocal leukoencephalopathy: extended follow-up of an observational study.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Survival Rate | 2001 |
Cidofovir in AIDS-associated progressive multifocal leukoencephalopathy: a monocenter observational study with clinical and JC virus load monitoring.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Survival Analysis; Viral Load | 2001 |
Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation.
Topics: Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retrospective Studies; Transplantation, Homologous; Treatment Outcome | 2001 |
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Syndromes; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Transplantation, Homologous; Treatment Failure; Viremia; Virus Activation | 2001 |
Topical treatment of acute adenoviral keratoconjunctivitis with 0.2% cidofovir and 1% cyclosporine: a controlled clinical pilot study.
Topics: Acute Disease; Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Adult; Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cyclosporine; Cytosine; DNA Primers; DNA, Viral; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Eye Infections, Viral; Female; Humans; Immunosuppressive Agents; Keratoconjunctivitis; Male; Middle Aged; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Treatment Outcome | 2001 |
Combined surgery and cidofovir is an effective treatment for genital warts in HIV-infected patients.
Topics: Adult; Antiviral Agents; Cidofovir; Combined Modality Therapy; Condylomata Acuminata; Cytosine; Electrocoagulation; Female; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies | 2002 |
[A new antiviral for genito-anal condylomas].
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Double-Blind Method; Female Urogenital Diseases; Humans; Male Urogenital Diseases; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Treatment Outcome; Tumor Virus Infections | 2002 |
The effects of cidofovir 1% with and without cyclosporin a 1% as a topical treatment of acute adenoviral keratoconjunctivitis: a controlled clinical pilot study.
Topics: Acute Disease; Adenovirus Infections, Human; Adenoviruses, Human; Adult; Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Conjunctiva; Cyclosporine; Cytosine; DNA Primers; DNA, Viral; Drug Therapy, Combination; Eye Infections, Viral; Eyelids; Female; Humans; Immunosuppressive Agents; Keratoconjunctivitis; Male; Middle Aged; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Safety | 2002 |
Intralesional cidofovir therapy for laryngeal papilloma in an adult cohort.
Topics: Antiviral Agents; Cidofovir; Cohort Studies; Cytosine; Drug Administration Schedule; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papilloma | 2002 |
A pilot study of cidofovir for progressive multifocal leukoencephalopathy in AIDS.
Topics: Adult; Antiviral Agents; Brain; Cerebrospinal Fluid; Cidofovir; Cytosine; HIV Infections; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Treatment Outcome | 2002 |
Pharmacokinetics and renal effects of cidofovir with a reduced dose of probenecid in HIV-infected patients with cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid | 2003 |
A scheduled protocol for the treatment of juvenile recurrent respiratory papillomatosis with intralesional cidofovir.
Topics: Antineoplastic Agents; Antineoplastic Protocols; Child; Child, Preschool; Cidofovir; Cytosine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Prospective Studies; Treatment Outcome | 2003 |
Is cidofovir a useful adjunctive therapy for recurrent respiratory papillomatosis in children?
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Child, Preschool; Cidofovir; Cytosine; Debridement; Female; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Prospective Studies; Treatment Outcome | 2004 |
Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anesthesia, General; Anesthesia, Local; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Female; Ganciclovir; Humans; Infusions, Intravenous; Intraoperative Complications; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Prospective Studies; Visual Acuity; Vitreous Hemorrhage | 2004 |
[Treatment of cutaneous human papilloma virus, poxvirus and herpes simplex virus infections with topical cidofovir in HIV positive patients].
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Poxviridae Infections; Skin Diseases, Viral | 2004 |
Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients.
Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome | 2004 |
Clinical responses to Cidofovir applied topically to women with high grade vulval intraepithelial neoplasia.
Topics: Administration, Topical; Adult; Aged; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Vulvar Neoplasms | 2005 |
Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell transplant recipients.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Microbial Sensitivity Tests; Organophosphonates | 2005 |
3.5-Year follow-up of intralesional cidofovir protocol for pediatric recurrent respiratory papillomatosis.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Protocols; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Retrospective Studies; Treatment Outcome | 2006 |
Intermediate-term and long-term results after treatment by cidofovir and excision in juvenile laryngeal papillomatosis.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Follow-Up Studies; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Organophosphonates; Papilloma; Papillomavirus Infections; Prospective Studies; Secondary Prevention; Severity of Illness Index; Treatment Outcome | 2006 |
Local administration of cidofovir for human papilloma virus associated skin lesions in transplant recipients.
Topics: Administration, Topical; Adolescent; Adult; Cidofovir; Cytosine; Female; Humans; Male; Organ Transplantation; Organophosphonates; Warts | 2007 |
Effect of topical ophthalmic application of cidofovir on experimentally induced primary ocular feline herpesvirus-1 infection in cats.
Topics: Administration, Topical; Animals; Antiviral Agents; Cat Diseases; Cats; Cidofovir; Conjunctivitis, Viral; Cytosine; Drug Administration Schedule; Herpesviridae; Herpesviridae Infections; Male; Organophosphonates | 2008 |
Cidofovir efficacy in recurrent respiratory papillomatosis: a randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Antineoplastic Agents; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Quality of Life; Respiratory Tract Neoplasms | 2008 |
The effect of low-dose cidofovir on the long-term outcome of polyomavirus-associated nephropathy in renal transplant recipients.
Topics: Adult; Aged; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections | 2009 |
Topical treatment of CIN 2+ by cidofovir: results of a phase II, double-blind, prospective, placebo-controlled study.
Topics: Administration, Topical; Adult; Antineoplastic Agents; Cidofovir; Combined Modality Therapy; Conization; Contraceptive Devices, Female; Cytosine; Double-Blind Method; Female; Gels; Humans; Organophosphonates; Papillomavirus Infections; Placebos; Prospective Studies; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2009 |
Late-onset hemorrhagic cystitis in children after hematopoietic stem cell transplantation for thalassemia and sickle cell anemia: a prospective evaluation of polyoma (BK) virus infection and treatment with cidofovir.
Topics: Adolescent; Adult; Anemia, Sickle Cell; BK Virus; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Incidence; Infant; Middle Aged; Organophosphonates; Polyomavirus Infections; Prospective Studies; Thalassemia; Tumor Virus Infections; Young Adult | 2010 |
A randomized, double-blind, placebo-controlled proof of concept trial of topical cidofovir, 1% and 3%, for the prevention of beard hair growth in men.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Double-Blind Method; Facial Dermatoses; Folliculitis; Hair Diseases; Humans; Male; Organophosphonates; Treatment Outcome | 2012 |
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.
Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Biological Availability; Capsule Endoscopy; Cidofovir; Cytosine; DNA Viruses; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intraocular Pressure; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Placebos; United States | 2012 |
Safety and efficacy of topical cidofovir to treat high-grade perianal and vulvar intraepithelial neoplasia in HIV-positive men and women.
Topics: Acquired Immunodeficiency Syndrome; Administration, Cutaneous; Adult; Aged; Antiviral Agents; Anus Neoplasms; Carcinoma in Situ; CD4 Lymphocyte Count; Cidofovir; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Proteins; Organophosphonates; Perineum; Prospective Studies; Vulvar Neoplasms | 2013 |
Relationship between clinical and BK virological response in patients with late hemorrhagic cystitis treated with cidofovir: a retrospective study from the European Group for Blood and Marrow Transplantation.
Topics: Adolescent; Adult; Allografts; Antiviral Agents; BK Virus; Child, Preschool; Cidofovir; Cystitis; Cytosine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Infant; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Time Factors; Viral Load; Viremia | 2013 |
Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Antigens, Viral; Antiviral Agents; Capsid Proteins; Child; Chromatography, Liquid; Cidofovir; Combined Modality Therapy; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunologic Deficiency Syndromes; Immunomagnetic Separation; Immunosuppressive Agents; Immunotherapy, Adoptive; Infant; Infant, Newborn; Interferon gamma Receptor; Interferon-gamma; Lymphocyte Transfusion; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interferon; Ribavirin; T-Cell Antigen Receptor Specificity; T-Lymphocyte Subsets; Transplantation, Homologous; Viremia | 2013 |
Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT³VIN): a multicentre, open-label, randomised, phase 2 trial.
Topics: Adult; Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Carcinoma in Situ; Cidofovir; Cytosine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Imiquimod; Middle Aged; Neoplasm Grading; Organophosphonates; Vulvar Neoplasms | 2014 |
Pharmacokinetics and safety of intravenous cidofovir for life-threatening viral infections in pediatric hematopoietic stem cell transplant recipients.
Topics: Acute Kidney Injury; Adenovirus Infections, Human; Adolescent; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpesviridae Infections; Humans; Male; Organophosphonates; Pilot Projects; Polyomavirus Infections; Viremia | 2015 |
Topical cidofovir to treat high-grade anal intraepithelial neoplasia in HIV-infected patients: a pilot clinical trial.
Topics: Administration, Topical; Adult; Antiviral Agents; Anus Neoplasms; Biopsy; Carcinoma in Situ; Cidofovir; Cytosine; HIV Infections; Humans; Male; Organophosphonates; Papillomavirus Infections; Pilot Projects; Treatment Outcome | 2016 |
Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brachytherapy; Carboplatin; Chemoradiotherapy; Cidofovir; Cytosine; Female; Humans; Middle Aged; Organophosphonates; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 2016 |
Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation.
Topics: Administration, Topical; Adult; Antiviral Agents; C-Reactive Protein; Cidofovir; Cytosine; Female; Follow-Up Studies; Gels; Humans; Organophosphonates; Surveys and Questionnaires; Time Factors; Uterine Cervical Dysplasia; Young Adult | 2018 |
920 other study(ies) available for cidofovir anhydrous and cytosine
| Article | Year |
|---|---|
Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
Topics: Animals; Antiviral Agents; Carbon Radioisotopes; Cells, Cultured; Cidofovir; Cytosine; Herpesviridae Infections; Humans; Kinetics; Magnetic Resonance Spectroscopy; Organophosphonates; Organophosphorus Compounds; Phosphates; Phosphorus | 1992 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1992 |
Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents.
Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Deoxyuracil Nucleotides; Drug Evaluation; Flow Cytometry; Herpesvirus 3, Human; Humans; Organophosphonates; Organophosphorus Compounds; Thymidine Kinase; Viral Envelope Proteins; Virus Replication | 1992 |
Comparative activity of various compounds against clinical strains of herpes simplex virus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Dextran Sulfate; Guanine; HeLa Cells; Heparin; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Virus Replication | 1992 |
Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Combinations; Ganciclovir; Immunologic Deficiency Syndromes; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins | 1992 |
Effect of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine on the replication and morphogenesis of herpes simplex virus type 1.
Topics: Animals; Antiviral Agents; Capsid; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; DNA, Viral; Kidney; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Proteins; Virus Replication | 1992 |
The activity of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine (HPMPC) against equine herpesvirus-1 (EHV-1) in cell cultures, mice and horses.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpesviridae Infections; Herpesvirus 1, Equid; Horse Diseases; Horses; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds | 1992 |
Pretreatment with topical 0.1% (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine inhibits adenovirus type 5 replication in the New Zealand rabbit ocular model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Colony Count, Microbial; Corneal Diseases; Corneal Stroma; Cytosine; Disease Models, Animal; Eye Infections, Viral; Female; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Premedication; Rabbits; Virus Replication | 1992 |
Pretreatment of the host cell with 1-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) is sufficient for its antiviral effect.
Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Drug Administration Schedule; Humans; In Vitro Techniques; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1992 |
Immunotoxic potential of antiviral drugs: effects of ganciclovir and (S)-1-(3-hydroxy-2-phosphonylmethoxy propyl) cytosine on lymphocyte transformation and delayed-type hypersensitivity responses.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Concanavalin A; Cytosine; Ganciclovir; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Phytohemagglutinins; Specific Pathogen-Free Organisms | 1992 |
Lack of retinal toxicity of the anticytomegalovirus drug (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Electroretinography; Half-Life; Injections; Ophthalmoscopy; Organophosphonates; Organophosphorus Compounds; Papio; Rabbits; Retina | 1992 |
Phosphonomethylether compounds as antiviral agents.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Haplorhini; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Structure-Activity Relationship | 1991 |
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay | 1991 |
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds | 1991 |
Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys.
Topics: Administration, Oral; Animals; Antibodies, Viral; Antiviral Agents; Chickenpox; Chlorocebus aethiops; Cidofovir; Cytosine; Herpesvirus 3, Human; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Viremia | 1991 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
Effects of phosphonylmethoxyalkyl-purine and -pyrimidine derivatives on TK+ and TK- HSV-1 keratitis in rabbits.
Topics: Adenine; Animals; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Hempa; Keratitis, Herpetic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Thymidine Kinase | 1991 |
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin | 1991 |
Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Guanosine Triphosphate; Humans; Male; Organophosphonates; Organophosphorus Compounds; Rats; Viral Plaque Assay; Virus Replication | 1991 |
Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; Guanine; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Structure-Activity Relationship; Tubercidin | 1990 |
Inhibitory effect of (S)-HPMPC, (S)-HPMPA, and 2'-nor-cyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro.
Topics: Adenine; Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; DNA; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Serotyping; Tumor Cells, Cultured; Viral Plaque Assay | 1991 |
Structure of 1-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine; an antiviral agent.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry, Physical; Cidofovir; Crystallization; Cytosine; Hydrogen Bonding; Molecular Structure; Organophosphonates; Organophosphorus Compounds; X-Ray Diffraction | 1991 |
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine | 1991 |
(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine in the therapy of thymidine kinase-positive and -deficient herpes simplex virus experimental keratitis.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Disease Models, Animal; Drug Administration Schedule; Female; Keratitis, Dendritic; Male; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Simplexvirus; Thymidine Kinase | 1991 |
Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice.
Topics: Animals; Antiviral Agents; Brain Stem; Cidofovir; Cytosine; Drug Administration Schedule; Encephalitis; Female; Ganciclovir; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Premedication | 1991 |
(S)-1-(3-hydroxy-2-(phosphonylmethoxy)propyl)cytosine (HPMPC): a potent antiherpesvirus agent.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytomegalovirus Infections; Cytosine; Herpesviridae Infections; Mice; Molecular Structure; Organophosphonates; Organophosphorus Compounds | 1990 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Peritoneal Cavity; Skin Diseases, Infectious | 1991 |
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Plaque Assay | 1990 |
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) against guinea pig cytomegalovirus infection in cultured cells and in guinea pigs.
Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Guinea Pigs; Organ Specificity; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay; Virus Replication | 1990 |
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine | 1990 |
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).
Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA; DNA Replication; DNA, Viral; Flow Cytometry; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1990 |
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells | 1989 |
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1988 |
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents.
Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Evaluation Studies as Topic; Ganciclovir; Humans; Interferons; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Radioimmunoassay; Staphylococcal Protein A; Time Factors; Virus Replication | 1994 |
Optimization of in vitro flux through hairless mouse skin of cidofovir, a potent nucleotide analog.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Gels; In Vitro Techniques; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Pharmaceutical Vehicles; Skin Absorption; Solubility | 1995 |
From the Food and Drug Administration.
Topics: Advertising; Antiviral Agents; Cidofovir; Commerce; Consumer Advocacy; Cytomegalovirus Retinitis; Cytosine; Drug Industry; Drugs, Investigational; Humans; Nicotiana; Organophosphonates; Organophosphorus Compounds; Patient Education as Topic; Pharmacoepidemiology; Plants, Toxic; United States; United States Food and Drug Administration | 1995 |
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Immunocompromised Host; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid | 1995 |
Treatment of anogenital papillomavirus infections with an acyclic nucleoside phosphonate analogue.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Female; Humans; Male; Organophosphonates; Organophosphorus Compounds; Papillomaviridae | 1995 |
AIDS therapy. New hope against blindness.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Blindness; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; RNA, Antisense | 1995 |
Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates.
Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Foscarnet; Organophosphonates; Organophosphorus Compounds; Vero Cells | 1995 |
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds | 1995 |
Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Fundus Oculi; Herpes Simplex; Liposomes; Longitudinal Studies; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis | 1995 |
Successful treatment of a squamous papilloma of the hypopharynx-esophagus by local injections of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
Topics: Aged; Antiviral Agents; Cidofovir; Cytosine; Esophageal Neoplasms; Female; Humans; Hypopharyngeal Neoplasms; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Tumor Virus Infections | 1995 |
Anticytomegaloviral activity and safety of cidofovir in patients with human immunodeficiency virus infection and cytomegalovirus viruria.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Urine | 1995 |
Antitrypanosomal activity of phosphonylmethoxyalkylpurines.
Topics: Adenine; Animals; Cidofovir; Cytosine; Female; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Purines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African | 1994 |
1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo.
Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Drug Stability; Female; Humans; Male; Mice; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley | 1994 |
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion in in vitro cell culture perfusion system.
Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Half-Life; Humans; Organophosphonates; Organophosphorus Compounds | 1994 |
HPMPC, a broad-spectrum topical antiviral agent, inhibits herpes simplex virus type 1 replication and promotes healing of dendritic keratitis in the New Zealand rabbit ocular model.
Topics: Administration, Topical; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine; Vero Cells; Virus Replication | 1994 |
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1994 |
Topical HPMPC inhibits adenovirus type 5 in the New Zealand rabbit ocular replication model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Female; Humans; Keratoconjunctivitis; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Replication; Virus Shedding | 1994 |
Kinetic analysis of the interaction between the diphosphate of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, ddCTP, AZTTP, and FIAUTP with human DNA polymerases beta and gamma.
Topics: Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Cytosine; Dideoxynucleotides; DNA Polymerase I; DNA Polymerase III; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Thymine Nucleotides; Zalcitabine; Zidovudine | 1994 |
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; DNA Restriction Enzymes; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral; Thymidine Kinase | 1994 |
Treatment with intravenous (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine of acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with AIDS.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus | 1994 |
Antimitotic and teratogenic effects of acyclic nucleotide analogues 1-(S)-(3-hydroxy-2-phosphonomethoxyethyl)cytosine (HPMPC) and 9-(2-phosphonomethoxyethyl) adenine (PMEA).
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Chick Embryo; Cidofovir; Cytosine; Female; Fibroblasts; Humans; Lung; Male; Mitosis; Organophosphonates; Organophosphorus Compounds; Polydactyly; Rats; Rats, Inbred BN; Rats, Inbred Lew | 1993 |
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis; Time Factors | 1994 |
Mechanism of uptake of the phosphonate analog (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in Vero cells.
Topics: Animals; Antiviral Agents; Carbon Radioisotopes; Cidofovir; Cytosine; Endocytosis; Organophosphonates; Organophosphorus Compounds; Sucrose; Temperature; Time Factors; Tritium; Vero Cells | 1993 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney; Liver; Lung; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vaccinia; Vaccinia virus; Virus Replication | 1993 |
Effects of phosphonylmethoxyalkyl derivatives studied with a murine model for abortion induced by equine herpesvirus 1.
Topics: Abortion, Spontaneous; Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpesviridae Infections; Herpesvirus 1, Equid; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Pregnancy; Virus Replication | 1993 |
Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cell Nucleus; Cidofovir; Cytosine; Herpesviridae; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Structure-Activity Relationship; Thymidine Kinase; Virus Replication | 1994 |
Comparative effect of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine treatment on cytomegalovirus-induced interstitial pneumonitis in allogeneic bone marrow transplant recipient rats.
Topics: Animals; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Male; Organophosphonates; Organophosphorus Compounds; Pulmonary Fibrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine.
Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation | 1993 |
The effect of (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine (HPMPC) on bovine herpesvirus-1 (BHV-1) infection and reactivation in cattle.
Topics: Animals; Antiviral Agents; Body Temperature; Cattle; Cidofovir; Cytosine; Dexamethasone; Drug Tolerance; Evaluation Studies as Topic; Eye; Herpesvirus 1, Bovine; Infectious Bovine Rhinotracheitis; Male; Nasal Cavity; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1993 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice.
Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Ganciclovir; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1993 |
Evaluation of HPMPC therapy for primary and recurrent genital herpes in mice and guinea pigs.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Herpes Genitalis; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Ultraviolet Rays; Vagina; Vaginal Diseases; Virus Replication | 1993 |
A new topical treatment for resistant herpes simplex infections.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance; Herpes Simplex; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Simplexvirus | 1993 |
Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Carriers; Eye Infections, Viral; Herpes Simplex; Herpesvirus 1, Human; Injections; Liposomes; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Retinitis; Vitreous Body | 1996 |
Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Drug Resistance, Microbial; Fibroblasts; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Plaque Assay | 1995 |
Suppression of rat adjuvant arthritis by some acyclic nucleotide analogs.
Topics: Adenine; Animals; Arthritis, Experimental; Cidofovir; Cytosine; Female; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Inbred BN; Rats, Inbred Lew | 1995 |
Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase.
Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA; Fibroblasts; Humans; Kinetics; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Viral Proteins | 1996 |
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds | 1995 |
Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Eye; Half-Life; Humans; Injections; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Tissue Distribution; Vitreous Body | 1996 |
Treatment of cytomegalovirus retinitis in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Routes; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Retinitis | 1996 |
Treatment of cytomegalovirus retinitis with intravitreous cidofovir in patients with AIDS. A preliminary report.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Progression; Female; Humans; Injections, Intralesional; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retinitis; Treatment Outcome; Vitreous Body | 1996 |
Intravitreal cidofovir for the maintenance treatment of cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Female; Follow-Up Studies; Humans; Injections; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retinal Detachment; Safety; Survival Rate; Vitreous Body | 1996 |
New developments in the treatment of CMV retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Injections; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1996 |
Therapeutic potential of Cidofovir (HPMPC, Vistide) for the treatment of DNA virus (i.e. herpes-, papova-, pox- and adenovirus) infections.
Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Cidofovir; Clinical Trials as Topic; Cytosine; DNA Viruses; DNA-Directed DNA Polymerase; Half-Life; Humans; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Point Mutation; Virus Diseases; Virus Replication | 1996 |
Current and experimental therapeutic options for cytomegalovirus disease.
Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds | 1996 |
Effect of partial retinal destruction and gliosis on the intravitreal pharmacokinetics of HPMPC.
Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Gliosis; Half-Life; Injections; Laser Coagulation; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Vitreous Body | 1995 |
A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 1996 |
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Evaluation of Cidofovir (HPMPC, GS-504) against adenovirus type 5 infection in vitro and in a New Zealand rabbit ocular model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antibodies, Viral; Cidofovir; Cytosine; Disease Models, Animal; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Eye; Female; Humans; Organophosphonates; Organophosphorus Compounds; Rabbits; Tears; Tumor Cells, Cultured | 1996 |
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Chlorocebus aethiops; Cidofovir; Cytosine; Injections, Intravenous; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Probenecid; Virus Diseases | 1996 |
Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats.
Topics: Administration, Cutaneous; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Cidofovir; Cytosine; Female; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; Tissue Distribution; Virus Diseases | 1996 |
Effect of probenecid on the distribution, metabolism, and excretion of cidofovir in rabbits.
Topics: Administration, Oral; Animals; Antiviral Agents; Autoradiography; Cidofovir; Cytosine; Injections, Intravenous; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Rabbits; Radiography; Tissue Distribution; Uricosuric Agents | 1996 |
Stability of cidofovir in 0.9% sodium chloride injection and in 5% dextrose injection.
Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Drug Stability; Glucose; Hydrogen-Ion Concentration; Injections; Organophosphonates; Organophosphorus Compounds; Osmolar Concentration; Particle Size; Polyvinyl Chloride; Sodium Chloride; Time Factors | 1996 |
Treatment of adenoviral conjunctivitis with topical cidofovir.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Humans; Male; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Self Medication | 1996 |
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid | 1996 |
An open letter to the FDA regarding changes in reporting procedures for drugs and biologics proposed in the wake of the FIAU tragedy.
Topics: Adverse Drug Reaction Reporting Systems; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Cost-Benefit Analysis; Cytosine; Drug Evaluation; Forms and Records Control; Humans; Organophosphonates; Organophosphorus Compounds; Safety Management; United States; United States Food and Drug Administration | 1996 |
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection.
Topics: Bone Marrow Cells; Cidofovir; Cytokines; Cytomegalovirus; Cytosine; Ganciclovir; Humans; Lipopolysaccharides; Organophosphonates; Organophosphorus Compounds; Stromal Cells; Virus Replication | 1996 |
An ocular model of Adenovirus type 5 infection in the rabbit.
Topics: Adenine; Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Eye Diseases; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Replication | 1995 |
From the Food and Drug Administration.
Topics: Anti-HIV Agents; Antiviral Agents; Breath Tests; Cidofovir; Cytosine; Helicobacter Infections; Helicobacter pylori; HIV Protease Inhibitors; Humans; Organophosphonates; Organophosphorus Compounds; Prostheses and Implants; Renal Insufficiency; Spinal Fusion; United States; United States Food and Drug Administration | 1996 |
Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Ganciclovir; Immunotoxins; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Ricin; Tumor Cells, Cultured | 1996 |
Cidofovir for AIDS-related retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Humans; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1996 |
Identification of enzymes catalyzing two-step phosphorylation of cidofovir and the effect of cytomegalovirus infection on their activities in host cells.
Topics: Antiviral Agents; Catalysis; Cell Line; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Kinetics; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Phosphotransferases | 1996 |
Isolation of human adenovirus type 5 variants resistant to the antiviral cidofovir.
Topics: Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Drug Resistance, Microbial; Humans; Lung Neoplasms; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured | 1996 |
High-performance liquid chromatographic determination of cytosine-containing compounds by precolumn fluorescence derivatization with phenacyl bromide: application to antiviral nucleosides and nucleotides.
Topics: Acetophenones; Animals; Antiviral Agents; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Cytosine Nucleotides; Hydrogen-Ion Concentration; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrometry, Fluorescence; Temperature | 1996 |
Topical corticosteroids reverse the antiviral effect of topical cidofovir in the Ad5-inoculated New Zealand rabbit ocular model.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Drug Therapy, Combination; Female; Glucocorticoids; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Prednisolone; Rabbits; Virus Replication | 1997 |
More new drugs for HIV and associated infections.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Bacterial Agents; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; HIV Infections; Humans; Isoquinolines; Nelfinavir; Nevirapine; Organophosphonates; Organophosphorus Compounds; Protease Inhibitors; Pyridines; Ritonavir; Sulfonic Acids | 1997 |
Activities of various compounds against murine and primate polyomaviruses.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Cidofovir; Cytosine; Mice; Organophosphonates; Organophosphorus Compounds; Polyomavirus; Polyomavirus Infections; Simian virus 40; Virus Replication | 1997 |
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Templates, Genetic | 1997 |
Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Antiviral Agents; Caco-2 Cells; Cell Line; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Cidofovir; Cytosine; Cytosol; Fibroblasts; Humans; Kinetics; Liver; Organophosphonates; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Prodrugs; Swine | 1997 |
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Prognosis; Retinitis | 1997 |
Gilead issues new warnings about cidofovir nephrotoxicity.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Monitoring; Humans; Organophosphonates; Organophosphorus Compounds; Renal Insufficiency | 1997 |
Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA | 1997 |
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA Probes; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Methylurea Compounds; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Phorbol Esters; Pyridines; Sarcoma, Kaposi; Tumor Cells, Cultured; Valine; Virus Replication | 1997 |
Low-dose intravitreal cidofovir (HPMPC) therapy of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Fundus Oculi; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Treatment Outcome; Vitreous Body | 1997 |
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis.
Topics: Adult; Antiviral Agents; Cidofovir; Cohort Studies; Cytomegalovirus Infections; Cytosine; Female; Humans; Injections, Intravenous; Iritis; Male; Middle Aged; Muscle Tonus; Muscular Diseases; Oculomotor Muscles; Organophosphonates; Organophosphorus Compounds; Retinitis; Retrospective Studies | 1997 |
Hypotony and visual loss with intravenous cidofovir treatment of cytomegalovirus retinitis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Injections, Intravenous; Male; Muscle Tonus; Muscular Diseases; Oculomotor Muscles; Organophosphonates; Organophosphorus Compounds; Retinitis | 1997 |
High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor) | 1997 |
Successful use of cidofovir in treating AIDS-related cytomegalovirus retinitis, encephalitis, and esophagitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Encephalitis, Viral; Esophagitis; Humans; Male; Organophosphonates; Organophosphorus Compounds; Retinitis | 1997 |
Metabolism of ganciclovir and cidofovir in cells infected with drug-resistant and wild-type strains of murine cytomegalovirus.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Ganciclovir; Mice; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Time Factors; Tumor Cells, Cultured | 1997 |
Effective treatment of experimental cytomegalovirus-induced encephalo-meningitis in immunocompromised rats with HPMPC.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; Immune Sera; Immunocompromised Host; Male; Meninges; Meningitis, Viral; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Inbred BN; Time Factors | 1997 |
Bioavailability and metabolism of cidofovir following topical administration to rabbits.
Topics: Administration, Topical; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Cidofovir; Cytosine; Isotope Labeling; Male; Organophosphonates; Organophosphorus Compounds; Rabbits; Tissue Distribution | 1997 |
Cidofovir transport in the pigmented rabbit conjunctiva.
Topics: Animals; Antiviral Agents; Benzalkonium Compounds; Biological Transport; Cidofovir; Conjunctiva; Cytosine; Edetic Acid; Hypertonic Solutions; In Vitro Techniques; Male; Organophosphonates; Organophosphorus Compounds; Osmolar Concentration; Rabbits; Temperature | 1997 |
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) inhibits HIV-1 replication in epithelial cells, but not T-lymphocytes.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; CD4 Antigens; Cell Line; Cidofovir; Cytosine; Genetic Engineering; HeLa Cells; Herpesvirus 1, Human; HIV-1; Humans; Organophosphonates; Organophosphorus Compounds; Phosphorylation; T-Lymphocytes; Virus Replication | 1997 |
An animal model for cidofovir (HPMPC) toxicity: intraocular pressure and histopathologic effects.
Topics: Animals; Cidofovir; Ciliary Body; Corneal Diseases; Cytosine; Disease Models, Animal; Eye Diseases; Guinea Pigs; Intraocular Pressure; Iritis; Microscopy, Electron; Organophosphonates; Organophosphorus Compounds; Pigment Epithelium of Eye; Retina; Retinal Diseases; Uveal Diseases | 1997 |
Drugs for non-HIV viral infections.
Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases | 1997 |
Successful treatment of cytomegalovirus encephalitis in an AIDS patient using cidofovir.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Encephalitis, Viral; Humans; Magnetic Resonance Imaging; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1997 |
Fanconi syndrome associated with cidofovir therapy.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Fanconi Syndrome; HIV Seropositivity; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 1997 |
Nephrogenic diabetes insipidus in a patient taking cidofovir.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Diabetes Insipidus, Nephrogenic; Humans; Male; Organophosphonates; Organophosphorus Compounds | 1997 |
Intraocular pressure and aqueous humor dynamics in patients with AIDS treated with intravitreal cidofovir (HPMPC) for cytomegalovirus retinitis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anterior Chamber; Antiviral Agents; Aqueous Humor; Cidofovir; Ciliary Body; Cytomegalovirus Infections; Cytosine; Drug Administration Schedule; Female; Fluorophotometry; Humans; Injections; Intraocular Pressure; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retinitis; Ultrasonography; Vitreous Body | 1997 |
Resolution of recalcitrant molluscum contagiosum virus lesions in human immunodeficiency virus-infected patients treated with cidofovir.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Male; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Remission Induction | 1997 |
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Male; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis, DNA | 1997 |
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency | 1997 |
Cidofovir for cytomegalovirus retinitis.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Ethics, Medical; Humans; Organophosphonates; Organophosphorus Compounds; Research Design | 1997 |
Stability of cidofovir in 0.9% sodium chloride injection for five days.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Stability; Organophosphonates; Organophosphorus Compounds; Polyethylenes; Polypropylenes; Polyvinyl Chloride; Sodium Chloride; Solutions; Temperature | 1997 |
Recurrent iritis after intravenous administration of cidofovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Iritis; Male; Organophosphonates; Organophosphorus Compounds; Recurrence | 1997 |
Treatment of verruca vulgaris with topical cidofovir.
Topics: Administration, Topical; Adolescent; Antiviral Agents; Child; Cidofovir; Cytosine; Female; Humans; Organophosphonates; Organophosphorus Compounds; Warts | 1997 |
Ophthalmic complications of HIV/AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Adverse events and autopsy findings after intravitreous cidofovir (HPMPC) therapy in patients with acquired immune deficiency syndrome (AIDS).
Topics: Adult; AIDS-Related Opportunistic Infections; Anterior Eye Segment; Antiviral Agents; Autopsy; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Follow-Up Studies; Fundus Oculi; Humans; Injections; Iritis; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Pigment Epithelium of Eye; Prospective Studies; Vitreous Body | 1997 |
[More successful therapy of CMV retinitis in AIDS patients].
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; HIV-1; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Antiviral drug susceptibility of human herpesvirus 8.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; DNA Replication; DNA, Viral; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
In vitro and in vivo inhibition of murine gamma herpesvirus 68 replication by selected antiviral agents.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Chlorocebus aethiops; Cidofovir; Cytosine; Gammaherpesvirinae; Herpesviridae Infections; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vero Cells; Virus Replication | 1998 |
Successful resolution of progressive multifocal leukoencephalopathy after combination therapy with cidofovir and cytosine arabinoside.
Topics: Adult; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds | 1998 |
The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice.
Topics: Adolescent; Animals; Antiviral Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Female; Ganciclovir; Genes, p53; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Injections, Intralesional; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Tumor Virus Infections | 1998 |
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Treatment Failure; Vitreous Body | 1998 |
Interpreting human cytomegalovirus antiviral drug susceptibility testing: the role of mixed virus populations.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds | 1998 |
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds | 1998 |
New issues in the management of cytomegalovirus retinitis in AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1998 |
Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antiviral Agents; Child; Cidofovir; Combined Modality Therapy; Cytosine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laser Therapy; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papilloma | 1998 |
New treatments for progressive multifocal leukoencephalopathy in HIV-1-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytosine; Drug Therapy, Combination; HIV Infections; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1998 |
Anterior uveitis and hypotony after intravenous cidofovir for the treatment of cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cohort Studies; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Incidence; Injections, Intravenous; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Risk Factors; Treatment Outcome; Uveitis, Anterior | 1998 |
Adenovirus cholecystitis in a patient with AIDS.
Topics: Adenoviridae Infections; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cholecystitis; Cidofovir; Cytosine; Humans; Male; Organophosphonates; Organophosphorus Compounds | 1998 |
Intravitreal and plasma cidofovir concentrations after intravitreal and intravenous administration in AIDS patients with cytomegalovirus retinitis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cohort Studies; Cytomegalovirus Infections; Cytosine; Humans; Injections; Injections, Intravenous; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Osmolar Concentration; Prospective Studies; Retinitis; Vitreous Body | 1998 |
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Lung Diseases; Nervous System Diseases; Organophosphonates; Organophosphorus Compounds; Retinitis | 1998 |
Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV-1; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence; Virus Activation; Virus Replication | 1998 |
[Fabrication of cidofovir ampules for intravitreal injections for cytomegalovirus retinitis].
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Chemistry, Pharmaceutical; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Compounding; Drug Packaging; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1998 |
Abatement of cutaneous Kaposi's sarcoma associated with cidofovir treatment.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Herpesvirus 8, Human; Humans; Male; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi; Skin Neoplasms | 1998 |
Probenecid hypersensitivity in AIDS: a case report.
Topics: Acquired Immunodeficiency Syndrome; Cidofovir; Cytosine; Drug Hypersensitivity; Herpes Simplex; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents | 1998 |
Influence of intravitreal injections of HPMPC and related nucleoside analogues on intraocular pressure in guinea pig eyes.
Topics: Animals; Antiviral Agents; Cidofovir; Ciliary Body; Cytosine; Guinea Pigs; Injections; Intraocular Pressure; Nucleosides; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Retina; Structure-Activity Relationship; Vitreous Body | 1998 |
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Recombination, Genetic; Virus Replication | 1998 |
Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: report of a case.
Topics: Aged; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Herpesvirus 8, Human; Humans; Injections, Intralesional; Male; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Sarcoma, Kaposi; Skin; Skin Neoplasms; Virus Replication | 1998 |
Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir.
Topics: Animals; Antiviral Agents; Body Weight; Brain Neoplasms; Cidofovir; Cytosine; Hemangioma; Incidence; Organophosphonates; Organophosphorus Compounds; Polyomavirus; Rats; Rats, Wistar; Skin Neoplasms; Survival Analysis | 1998 |
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine | 1998 |
Effects of topical and subconjunctival cidofovir (HPMPC) in an animal model.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Ciliary Body; Conjunctiva; Cornea; Corneal Edema; Cytosine; Guinea Pigs; Injections; Intraocular Pressure; Iris; Keratitis; Models, Biological; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Retina | 1998 |
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line.
Topics: Anti-HIV Agents; Antiviral Agents; Brain; Cells, Cultured; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Enzyme Inhibitors; Fetus; Humans; JC Virus; Neurons; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Topotecan; Tumor Virus Infections; Virus Replication; Zidovudine | 1998 |
A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.
Topics: Amino Acid Sequence; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Repression; Exonucleases; Ganciclovir; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Point Mutation; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication | 1998 |
Incidence of foscarnet resistance and cidofovir resistance in patients treated for cytomegalovirus retinitis. The Cytomegalovirus Retinitis and Viral Resistance Study Group.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Resistance; Female; Foscarnet; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies | 1998 |
Effect of oral probenecid coadministration on the chronic toxicity and pharmacokinetics of intravenous cidofovir in cynomolgus monkeys.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Injections, Intravenous; Kidney; Macaca fascicularis; Male; Organ Size; Organophosphonates; Organophosphorus Compounds; Probenecid | 1998 |
Treatment of acyclovir-resistant, foscarnet-unresponsive HSV infection with topical cidofovir in a child with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Anti-HIV Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Microbial; Facial Dermatoses; Foscarnet; Herpes Simplex; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Failure | 1998 |
[Comparison of the in vitro sensitivity to cidofovir and ganciclovir of clinical cytomegalovirus isolates. Coordinated Action Group 11].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 1998 |
Isolation and identification of a metabolite of cidofovir from rat kidney.
Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Injections, Intravenous; Kidney; Magnetic Resonance Spectroscopy; Male; Organophosphonates; Organophosphorus Compounds; Rats | 1998 |
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Female; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Prospective Studies; Survival Rate; Urine; Viremia | 1998 |
[Intravitreal injection of cidofovir in cytomegalovirus retinitis].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1998 |
[Manufacturing of cidofovir for intravitreal injections in cytomegalovirus retinitis].
Topics: Antiviral Agents; Chemistry, Pharmaceutical; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Industry; Drug Packaging; Europe; Humans; Injections; Organophosphonates; Organophosphorus Compounds; United States; Vitreous Body | 1998 |
Prognostic value of JC virus load in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy.
Topics: AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; DNA Primers; DNA Probes; DNA, Viral; Female; HIV-1; Humans; JC Virus; Male; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Statistics, Nonparametric; Tumor Virus Infections; Viral Load | 1998 |
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Cytomegalovirus iritis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Fatal Outcome; Humans; Immunohistochemistry; Iris; Iritis; Male; Organophosphonates; Organophosphorus Compounds | 1998 |
Discontinuing anticytomegalovirus therapy in patients with immune reconstitution after combination antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Female; Ganciclovir; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Viral Load | 1998 |
Successful treatment of Kaposi's sarcoma with a combination of antiviral drug therapy and chemotherapy: two case reports.
Topics: Adult; Antibiotics, Antineoplastic; Antiviral Agents; Cidofovir; Cytosine; Daunorubicin; Drug Therapy, Combination; Humans; Male; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi; Treatment Outcome | 1998 |
Abatement of cutaneous Kaposi's sarcoma associated with cidofovir treatment.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi; Skin Neoplasms | 1998 |
Comparative antiviral efficacies of cidofovir, trifluridine, and acyclovir in the HSV-1 rabbit keratitis model.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Trifluridine; Virus Replication; Virus Shedding | 1999 |
Pharmacokinetics of cidofovir in renal insufficiency and in continuous ambulatory peritoneal dialysis or high-flux hemodialysis.
Topics: Adult; Aged; Anti-HIV Agents; Cidofovir; Creatinine; Cytosine; Drug Administration Schedule; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Severity of Illness Index | 1999 |
Incidence of immune recovery vitritis in cytomegalovirus retinitis patients following institution of successful highly active antiretroviral therapy.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; California; Cidofovir; Cohort Studies; Cytomegalovirus Retinitis; Cytosine; Eye Diseases; Follow-Up Studies; Humans; Incidence; Inflammation; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retrospective Studies; Syndrome; Time Factors; Visual Acuity; Vitreous Body | 1999 |
Intravenous cidofovir-induced iritis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Injections, Intravenous; Iritis; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 1999 |
Vitrectomy and silicone oil tamponade for cidofovir-associated hypotony with ciliary body detachment.
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Eye Diseases; Humans; Lens Implantation, Intraocular; Lens, Crystalline; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Silicone Oils; Ultrasonography; Vitrectomy | 1999 |
Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Guanosine; Guinea Pigs; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Viral Plaque Assay; Virus Replication | 1999 |
Enhanced chemical stability of the intracellular prodrug, 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine, relative to its parent compound, cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Stability; Hydrolysis; Kinetics; Organophosphonates; Organophosphorus Compounds; Prodrugs; Solubility | 1999 |
Response to cidofovir after failure of antiretroviral therapy alone in AIDS-associated progressive multifocal leukoencephalopathy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Brain; Cidofovir; Cytosine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates; Organophosphorus Compounds | 1999 |
Iritis associated with intravenous cidofovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Infusions, Intravenous; Iritis; Male; Organophosphonates; Organophosphorus Compounds | 1999 |
Successful treatment of adenovirus disease with intravenous cidofovir in an unrelated stem-cell transplant recipient.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning; Transplantation, Homologous | 1999 |
An aggressive and invasive growth of juvenile papillomas involving the total respiratory tract.
Topics: Adult; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; DNA, Viral; Fatal Outcome; Humans; Male; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Respiratory Tract Neoplasms; Time Factors; Tongue Neoplasms; Tumor Suppressor Protein p53 | 1998 |
Monitoring the response of AIDS-related progressive multifocal leukoencephalopathy to HAART and cidofovir by PCR for JC virus DNA in the CSF.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Cidofovir; Cytosine; DNA, Viral; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Monitoring, Physiologic; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Polymerase Chain Reaction; Polyomaviridae | 1999 |
Selective inhibition of human papillomavirus-induced cell proliferation by (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
Topics: Antiviral Agents; Cell Cycle; Cell Transformation, Viral; Cells, Cultured; Cidofovir; Cytosine; Humans; Keratinocytes; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Tumor Virus Infections | 1999 |
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral | 1999 |
A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors.
Topics: Antiviral Agents; Cidofovir; Colorimetry; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Fibroblasts; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tetrazolium Salts; Virus Replication | 1999 |
Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines.
Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Transformed; Cidofovir; COS Cells; Cytosine; HeLa Cells; Humans; Inhibitory Concentration 50; Keratinocytes; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Time Factors; Tumor Cells, Cultured | 1998 |
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Time Factors; Uterine Cervical Neoplasms | 1998 |
Topical cidofovir for severe molluscum contagiosum.
Topics: Administration, Topical; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Male; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Wiskott-Aldrich Syndrome | 1999 |
Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.
Topics: Adenine; Animals; Antimalarials; Cidofovir; Cytosine; Erythrocytes; Ganciclovir; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Plasmodium falciparum; Structure-Activity Relationship | 1999 |
Cidofovir and experimental herpetic stromal disease.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Corneal Stroma; Cytosine; Female; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Trifluridine | 1999 |
Comment: cidofovir in the treatment of cytomegaloviral disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Organophosphonates; Organophosphorus Compounds | 1999 |
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Ganciclovir; Genotype; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Prospective Studies; Retinitis; Viral Load; Viral Proteins | 1999 |
Surgical repair of cytomegalovirus-related retinal detachment without silicone oil in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Fluorocarbons; Follow-Up Studies; HIV-1; Humans; Laser Coagulation; Male; Organophosphonates; Organophosphorus Compounds; Retinal Detachment; Scleral Buckling; Silicone Oils; Sulfur Hexafluoride; Visual Acuity; Vitrectomy | 1999 |
Remission of AIDS-associated progressive multifocal leukoencephalopathy after cidofovir therapy.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Organophosphorus Compounds; Remission Induction | 1999 |
The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.
Topics: Adenine; Amino Acid Sequence; Animals; Anion Transport Proteins; Antiviral Agents; Base Sequence; Biological Transport; Carrier Proteins; Cidofovir; Cloning, Molecular; Cytosine; DNA, Complementary; Humans; Immunoblotting; Kidney; Molecular Sequence Data; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rats | 1999 |
Prolonged survival without neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Demyelinating Diseases; Female; France; HIV; HIV Long-Term Survivors; HIV Protease Inhibitors; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prospective Studies; Retrospective Studies; Survival Rate; Time Factors; Viral Load | 1999 |
Anterior uveitis associated with intravenous cidofovir use in patients with cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Case-Control Studies; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Risk Factors; Uveitis, Anterior | 1999 |
Intralesional or topical cidofovir (HPMPC, VISTIDE) for the treatment of recurrent genital warts in HIV-1-infected patients.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; DNA, Viral; HIV; Humans; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Recurrence; Tumor Virus Infections; Viral Load | 1999 |
Intralesional cidofovir for recurrent respiratory papillomatosis in children.
Topics: Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Organophosphonates; Organophosphorus Compounds; Papilloma; Pilot Projects; Prospective Studies; Recurrence; Treatment Outcome | 1999 |
Management of progressive outer retinal necrosis with cidofovir in a human immunodeficiency virus-infected patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Herpes Zoster; Humans; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Retinal Necrosis Syndrome, Acute; Severity of Illness Index; Treatment Outcome | 1999 |
Cystoid macular edema following immune recovery and treatment with cidofovir for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Injections, Intravenous; Macular Edema; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Vitreous Body | 1999 |
Aryl ester prodrugs of cyclic HPMPC. I: Physicochemical characterization and in vitro biological stability.
Topics: Animals; Antiviral Agents; Blood; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Dogs; Drug Stability; Humans; Hydrolysis; Intestinal Mucosa; Ligands; Liver; Organophosphonates; Organophosphorus Compounds; Prodrugs; Salicylates; Solubility; Stereoisomerism; Swine; Time Factors | 1999 |
Cidofovir-induced end-stage renal failure.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 1999 |
Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challenge.
Topics: Administration, Intranasal; Aerosols; Animals; Antiviral Agents; Bronchi; Cidofovir; Cowpox; Cytosine; Female; Hemorrhage; Mice; Mice, Inbred BALB C; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pulmonary Alveoli; Smallpox; Vaccination | 2000 |
Uveitis in patients treated with intravenous cidofovir.
Topics: Adult; Anti-HIV Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; HIV Seropositivity; Humans; Injections, Intravenous; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retinitis; Retrospective Studies; Uveitis | 1999 |
Intravenous cidofovir for compassionate use in AIDS patients with cytomegalovirus retinitis. Spanish Cidofovir Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cohort Studies; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2000 |
Successful resolution of progressive multifocal leukoencephalopathy after combination therapy with cidofovir and cytosine arabinoside.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2000 |
Ocular complications of intravenous cidofovir for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Uveitis, Anterior | 1999 |
The antisense oligonucleotide ISIS 2922 prevents cytomegalovirus-induced upregulation of IL-8 and ICAM-1 in cultured human fibroblasts.
Topics: Antiviral Agents; Cells, Cultured; Chemotaxis, Leukocyte; Cidofovir; Cytomegalovirus Infections; Cytosine; Fibroblasts; Foscarnet; Ganciclovir; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-8; Neutrophils; Oligonucleotides, Antisense; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Up-Regulation | 2000 |
Acute murine cytomegalovirus infection: a model for determining antiviral activity against CMV induced hepatitis.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Body Weight; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Ganciclovir; Hepatitis, Viral, Animal; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1999 |
Efficacy of topical cidofovir on multiple adenoviral serotypes in the New Zealand rabbit ocular model.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Female; Keratoconjunctivitis; Organophosphonates; Organophosphorus Compounds; Rabbits; Viral Plaque Assay; Virus Cultivation; Virus Replication; Virus Shedding | 2000 |
No apparent effect of cidofovir in epidermodysplasia verruciformis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Epidermodysplasia Verruciformis; Humans; Male; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Treatment Failure | 2000 |
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
Topics: Adenine; Alanine; Animals; Anion Transport Proteins; Antiviral Agents; Biological Transport; Carrier Proteins; CHO Cells; Cidofovir; Cricetinae; Cytosine; Humans; Kidney; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Probenecid | 2000 |
[Antiviral effect of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine on adenovirus].
Topics: Adenoviridae; Antiviral Agents; Cidofovir; Cytosine; Organophosphonates; Organophosphorus Compounds | 2000 |
Cidofovir for the treatment of Kaposi's sarcoma in an HIV-negative homosexual man.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; HIV Seronegativity; Humans; Male; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi; Skin Neoplasms | 1999 |
Cidofovir ocular toxicity is related to previous ocular history.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cataract Extraction; Cidofovir; Cytosine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Mydriatics; Organophosphonates; Organophosphorus Compounds; Uveitis | 2000 |
Susceptibility of human herpesvirus 6 to antiviral compounds by flow cytometry analysis.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Flow Cytometry; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 2000 |
Topical cidofovir is effective in treating extensive penile condylomata acuminata.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Humans; Male; Organophosphonates; Organophosphorus Compounds; Penile Diseases | 2000 |
Topical effects of cidofovir on cutaneous rabbit warts: treatment regimen and inoculum dependence.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cottontail rabbit papillomavirus; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Time Factors; Warts | 2000 |
Successful treatment of recalcitrant condyloma with topical cidofovir.
Topics: Administration, Topical; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Penile Diseases | 2000 |
Lack of reactivation of cytomegalovirus retinitis in an AIDS patient, during and after stopping long-term cidofovir treatment: case report.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Administration Schedule; Humans; Male; Organophosphonates; Organophosphorus Compounds; Virus Activation | 2000 |
Large plantar wart caused by human papillomavirus-66 and resolution by topical cidofovir therapy.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Biopsy; Cidofovir; Cytosine; Diagnosis, Differential; DNA, Viral; Female; Foot Dermatoses; Humans; Male; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Skin; Warts | 2000 |
Topical cidofovir: a novel treatment for recalcitrant molluscum contagiosum in children infected with human immunodeficiency virus 1.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Drug Administration Schedule; Facial Dermatoses; HIV-1; Humans; Male; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds; Perineum | 2000 |
Unsuccessful treatment with cidofovir and cytarabine in progressive multifocal leukoencephalopathy associated with dermatomyositis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds; Treatment Failure | 2000 |
Treatment of cowpox virus respiratory infections in mice with ribavirin as a single agent or followed sequentially by cidofovir.
Topics: Animals; Antiviral Agents; Body Weight; Cell Line; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Lung; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Respiratory Tract Infections; Ribavirin; Vero Cells; Viral Plaque Assay | 2000 |
Treatment of BK virus-associated hemorrhagic cystitis and simultaneous CMV reactivation with cidofovir.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematuria; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Virus Activation | 2000 |
Intranasal treatment of cowpox virus respiratory infections in mice with cidofovir.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Female; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Respiratory System; Respiratory Tract Infections; Vero Cells; Viral Plaque Assay | 2000 |
CMV complications in common variable immunodeficiency.
Topics: Adult; Antiviral Agents; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cidofovir; Colitis; Common Variable Immunodeficiency; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Cytotoxicity Tests, Immunologic; Encephalitis, Viral; Female; Foscarnet; Humans; K562 Cells; Killer Cells, Natural; Myelitis; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Viral Matrix Proteins | 2000 |
[Stopping secondary prevention in AIDS patients with inactive CMV retinitis treated with HAART (highly active antiretroviral therapy)].
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 2000 |
Ocular side-effects from systemic HPMPC (Cidofovir) for a non-ocular cytomegalovirus infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Probenecid; Uveitis, Anterior | 2000 |
Progressive multifocal leukoencephalopathy treated with cidofovir in HIV-infected patients receiving highly active anti-retroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytosine; Female; HIV Infections; HIV-1; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds | 2000 |
Resistant herpes simplex virus type 1 infection: an emerging concern after allogeneic stem cell transplantation.
Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Drug Resistance, Microbial; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Transplantation, Homologous | 2000 |
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Ganciclovir; Gene Deletion; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases; Transfection | 2000 |
Cidofovir inhibits growth of B16 melanoma cells in vivo.
Topics: Animals; Antineoplastic Agents; Body Weight; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Skin Neoplasms | 2000 |
Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage.
Topics: Animals; Antigen-Presenting Cells; Aorta; Arteritis; Autoimmunity; Cidofovir; Cytosine; Gammaherpesvirinae; Interferon gamma Receptor; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Receptors, Interferon; Virus Replication | 2000 |
Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant.
Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance; Female; Foscarnet; Herpes Simplex; Humans; Infant; Organophosphonates; Organophosphorus Compounds | 2000 |
Severe irreversible proximal renal tubular acidosis and azotaemia secondary to cidofovir.
Topics: Acidosis, Renal Tubular; Adult; Anti-HIV Agents; Cidofovir; Cytosine; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds; Uremia | 2000 |
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Fatal Outcome; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pneumonia, Viral; Polymerase Chain Reaction; Postoperative Complications | 2000 |
Failure of cidofovir therapy in progressive multifocal leukoencephalopathy unrelated to human immunodeficiency virus.
Topics: Anti-HIV Agents; Brain; Cidofovir; Cytosine; Female; HIV Infections; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Failure | 2001 |
Resolution of recalcitrant human papillomavirus gingival infection with topical cidofovir.
Topics: Anti-Infective Agents, Local; Antiviral Agents; Cidofovir; Cytosine; Gingival Diseases; HIV Infections; Humans; Inclusion Bodies, Viral; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections | 2000 |
In vivo anti-papillomavirus activity of nucleoside analogues including cidofovir on CRPV-induced rabbit papillomas.
Topics: Animals; Antiviral Agents; Cidofovir; Cottontail rabbit papillomavirus; Cytosine; Disease Models, Animal; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomavirus Infections; Rabbits; Treatment Outcome; Tumor Virus Infections | 2000 |
Effects of diclofenac or ketorolac on the inhibitory activity of cidofovir in the Ad5/NZW rabbit model.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cidofovir; Corneal Stroma; Cytosine; Diclofenac; Drug Interactions; Drug Therapy, Combination; Eye Infections, Viral; Female; Humans; Keratitis; Ketorolac Tromethamine; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Virus Replication; Virus Shedding | 2001 |
[Severe alopecia caused by cidofovir]].
Topics: Adult; AIDS-Related Opportunistic Infections; Alopecia; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Humans; Male; Organophosphonates; Organophosphorus Compounds | 2000 |
Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients. The Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Data Collection; Drug Evaluation; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Renal Insufficiency; Retrospective Studies; Survival Rate; Transplantation, Homologous; Treatment Outcome | 2001 |
Parapoxviruses are strongly inhibited in vitro by cidofovir.
Topics: Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Organophosphonates; Organophosphorus Compounds; Parapoxvirus; Poxviridae Infections; Sheep; Vaccinia; Vaccinia virus; Virus Replication | 2000 |
Isolation and analysis of an aciclovir-resistant murine cytomegalovirus mutant.
Topics: Acyclovir; Amino Acid Substitution; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Codon; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Ganciclovir; Inhibitory Concentration 50; Mice; Muromegalovirus; Mutation; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Virus Replication | 2001 |
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Treatment Outcome; Virus Activation | 2001 |
Systemic cidofovir in papillomatosis.
Topics: Antiviral Agents; Child; Cidofovir; Cytosine; Female; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Respiratory Tract Neoplasms; Tomography, X-Ray Computed | 2001 |
In vitro effects of antiviral agents on human keratocytes.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Colorimetry; Corneal Stroma; Cytosine; Dose-Response Relationship, Drug; Fibroblasts; Ganciclovir; Humans; Idoxuridine; Microscopy, Phase-Contrast; Organophosphonates; Organophosphorus Compounds; Trifluridine | 2001 |
Diagnostic and therapeutic dilemmas of a large scrotal lesion in an AIDS patient.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Biopsy; Cidofovir; Cytosine; Diagnosis, Differential; Fluorescent Antibody Technique, Direct; Herpes Genitalis; Herpesvirus 2, Human; Humans; Hyperplasia; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Scrotum; Skin; Skin Ulcer | 2001 |
Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Burkitt Lymphoma; Cidofovir; Cytosine; Herpesvirus 4, Human; Herpesvirus 8, Human; HIV Long-Term Survivors; HIV Protease Inhibitors; Humans; Interferon-alpha; Lymphoma, B-Cell; Male; Organophosphonates; Organophosphorus Compounds; Pleural Effusion; Sarcoma, Kaposi; Time Factors | 2001 |
Failure of cidofovir to reduce CMV-antigenemia in a child transplanted from a matched unrelated donor.
Topics: Adenoviridae; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Clinical presentation and antiviral therapy for poxvirus infection in pudu (Pudu puda).
Topics: Animal Diseases; Animals; Animals, Zoo; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Disease Outbreaks; Euthanasia; Female; Male; Microscopy, Electron; Neutralization Tests; Organophosphonates; Organophosphorus Compounds; Perissodactyla; Poxviridae; Poxviridae Infections; Tongue | 2000 |
Combination treatment with intralesional cidofovir and viral-DNA vaccination cures large cottontail rabbit papillomavirus-induced papillomas and reduces recurrences.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cottontail rabbit papillomavirus; Cytosine; Female; Genes, Viral; Injections, Intralesional; Male; Neoplasm Recurrence, Local; Oncogene Proteins, Viral; Organophosphonates; Organophosphorus Compounds; Rabbits; Time Factors; Vaccines, DNA; Viral Vaccines; Warts | 2001 |
Topical cidofovir for bowenoid papulosis in an HIV-infected patient.
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Anus Neoplasms; Carcinoma in Situ; Carcinoma, Squamous Cell; Cidofovir; Cytosine; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds | 2001 |
Enhancement of transplantation-associated atherosclerosis by CMV, which can be prevented by antiviral therapy in the form of HPMPC.
Topics: Animals; Antiviral Agents; Aorta; Arteriosclerosis; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Graft Rejection; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic; Tunica Intima; Tunica Media; Virus Replication | 1994 |
Potent inhibition of hemangiosarcoma development in mice by cidofovir.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Transformed; Cidofovir; Cytosine; Female; Hemangiosarcoma; Mice; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Peritoneal Neoplasms; Survival Rate | 2001 |
Ganciclovir and cidofovir treatment of cytomegalovirus-induced myocarditis in mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Muromegalovirus; Myocarditis; Organophosphonates; Organophosphorus Compounds | 2001 |
Treatment of adenovirus infections in patients undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; France; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Ribavirin; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2001 |
Successful preemptive cidofovir treatment for CMV antigenemia after dose-reduced conditioning and allogeneic blood stem cell transplantation.
Topics: Adult; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Feasibility Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Mycoses; Myeloablative Agonists; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Preventive Medicine; Prospective Studies; Transplantation Conditioning; Viral Matrix Proteins | 2001 |
Successful treatment of recurrent vulvar intraepithelial neoplasia resistant to interferon and isotretinoin with cidofovir.
Topics: Administration, Oral; Administration, Topical; Adult; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Drug Resistance, Multiple; Female; Humans; Injections, Subcutaneous; Interferons; Isotretinoin; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Uterine Cervical Dysplasia; Vulvar Neoplasms | 2001 |
FDA grants marketing clearance of Vistide for the treatment of CMV retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Approval; Humans; Organophosphonates; Organophosphorus Compounds; United States; United States Food and Drug Administration | 1996 |
CMV retinitis: a clinical management update.
Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds; Patient Participation; Vitreous Body | 1996 |
Black-bordered warning box for cidofovir.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytosine; Drug Labeling; Humans; Injections, Intravenous; Kidney; Organophosphonates; Organophosphorus Compounds | 1997 |
Pharmacia and Upjohn and Gilead sciences receive European recommendation for cidofovir.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Administration Schedule; Drug Industry; Europe; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Product Surveillance, Postmarketing | 1997 |
Gilead announces phase I/II data insufficient for marketing clearance of FORVADE topical gel to treat refractory herpes in patients with AIDS.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytosine; Herpes Simplex; Humans; Investigational New Drug Application; Organophosphonates; Organophosphorus Compounds; United States; United States Food and Drug Administration | 1997 |
Second National Retrovirus conference: a further report.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cause of Death; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Paclitaxel; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Tuberculosis | 1995 |
Advances, challenges and growing frustration.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cachexia; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Costs; Drug Therapy, Combination; Growth Hormone; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Immunity, Cellular; Infectious Disease Transmission, Vertical; Organophosphonates; Organophosphorus Compounds; Politics; Reverse Transcriptase Inhibitors; Zidovudine | 1995 |
Advances in the treatment of CMV.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Eye; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Quality of Life | 1995 |
Herpesviruses.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Complementary Therapies; Cytosine; Famciclovir; Foscarnet; Herpesviridae Infections; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine; Viral Vaccines | 1995 |
Cidofovir approved.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Administration Schedule; Humans; Organophosphonates; Organophosphorus Compounds; Quality of Life | 1996 |
Anti-HIV agents at ICAAC.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Kidney; Mutation; Nelfinavir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sulfonic Acids; Treatment Failure; Viral Load | 1996 |
Acyclovir-resistant herpes: expanded access available for cidofovir gel (Forvade).
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Gels; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Update on cidofovir for CMV retinitis.
Topics: Administration, Topical; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds | 1997 |
Drug-resistant herpes: cidofovir gel in limbo. Interview with Jay Lalezari, M.D. Interview by John S. James.
Topics: Administration, Topical; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Drug Approval; Drug Resistance, Microbial; Gels; Herpesviridae Infections; Organophosphonates; Organophosphorus Compounds; Treatment Outcome; United States; United States Food and Drug Administration | 1997 |
Fomivirsen.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Foscarnet; Ganciclovir; Health Services Accessibility; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides | 1998 |
Cidofovir.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Interactions; Drug Therapy, Combination; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents | 1998 |
A rocky road for nucleotide analogs.
Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1998 |
Neurology update.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Antiviral Agents; Brain; Cerebrospinal Fluid; Chicago; Cidofovir; Clinical Trials as Topic; Cohort Studies; Congresses as Topic; Cytosine; HIV Infections; Humans; Leukoencephalopathy, Progressive Multifocal; Mutation; Organophosphonates; Organophosphorus Compounds; RNA, Viral; Viral Load | 1999 |
The effects of cidofovir on progressive multifocal leukoencephalopathy: an MRI case study.
Topics: Adult; Anti-HIV Agents; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Organophosphorus Compounds | 2001 |
[Anterior uveitis and cidofovir].
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Cidofovir; Creatinine; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Ophthalmoscopy; Organophosphonates; Organophosphorus Compounds; Recurrence; Retrospective Studies; Time Factors; Tissue Distribution; Uveitis, Anterior | 2001 |
Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cidofovir; Cytosine; Female; Humans; Injections, Intravenous; Interferon alpha-2; Interferon-alpha; Laryngeal Neoplasms; Lung Neoplasms; Organophosphonates; Organophosphorus Compounds; Papilloma; Recombinant Proteins; Tracheal Neoplasms | 2001 |
Successful treatment of aids related PML with HAART and cidofovir.
Topics: Aged; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; Cidofovir; Cytosine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates; Organophosphorus Compounds | 2001 |
Cidofovir treatment of human polyomavirus-associated acute haemorrhagic cystitis.
Topics: Adolescent; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; Hemorrhage; Humans; Male; Organophosphonates; Organophosphorus Compounds; Polyomavirus; Polyomavirus Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Tumor Virus Infections | 2001 |
Inhibition of fibroblast growth factor-2-induced vascular tumor formation by the acyclic nucleoside phosphonate cidofovir.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Apoptosis; Brain Neoplasms; Cell Division; Chick Embryo; Cidofovir; Cytosine; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Hemangioendothelioma; Mice; Mice, Nude; Mice, SCID; Neovascularization, Pathologic; Neovascularization, Physiologic; Organophosphonates; Organophosphorus Compounds; Transfection; Tumor Cells, Cultured | 2001 |
The antiviral resistance and replication of cidofovir-resistant adenovirus variants in the New Zealand White rabbit ocular model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Drug Resistance, Microbial; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Cultivation; Virus Replication | 2001 |
Treatment of lethal vaccinia virus respiratory infections in mice with cidofovir.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cidofovir; Cowpox virus; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Mice; Mice, Inbred BALB C; Nose; Organ Specificity; Organophosphonates; Organophosphorus Compounds; Paranasal Sinuses; Pneumonia, Viral; Spleen; Vaccinia; Vaccinia virus; Viral Load; Viremia | 2001 |
A case of human orf in an immunocompromised patient treated successfully with cidofovir cream.
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Ecthyma, Contagious; Female; Hand Dermatoses; Humans; Immunocompromised Host; Orf virus; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Glass vials for small volume parenterals: influence of drug and manufacturing processes on glass delamination.
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Cidofovir; Cytosine; Disinfection; Drug Stability; Glass; Infusions, Parenteral; Microscopy, Electron, Scanning; Organophosphonates; Organophosphorus Compounds; Pharmaceutical Solutions; Sterilization; Stress, Mechanical; Surface Properties | 2001 |
Reversal of CSF positivity for JC virus genome by cidofovir in a patient with systemic lupus erythematosus and progressive multifocal leukoencephalopathy.
Topics: Adult; Antiviral Agents; Brain; Cidofovir; Cytosine; DNA, Viral; Fatal Outcome; Female; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Organophosphonates; Organophosphorus Compounds; Renal Insufficiency; Treatment Outcome | 2001 |
The good and evil of HAART in HIV-related progressive multifocal leukoencephalopathy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Survival Analysis | 2001 |
Effects of cidofovir on the pathogenesis of a lethal vaccinia virus respiratory infection in mice.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Blood Gas Monitoring, Transcutaneous; Body Weight; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Injections, Intraperitoneal; Lung; Mice; Mice, Inbred BALB C; Organ Size; Organophosphonates; Organophosphorus Compounds; Respiratory System; Respiratory Tract Infections; Time Factors; Vaccinia; Vaccinia virus; Vero Cells; Viral Plaque Assay; Virus Replication | 2001 |
[Evaluation of antiviral agents for adenovirus using the MTT method in vitro].
Topics: Acyclovir; Adenoviridae; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Foscarnet; Humans; Organophosphonates; Organophosphorus Compounds; Zalcitabine | 2000 |
Strategies for management of cytomegalovirus (CMV) infection after allogeneic bone marrow transplantation: the "doubling of baseline CMV pp65 antigenemia" and the "cidofovir as rescue treatment approaches.
Topics: Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Recurrence; Salvage Therapy; Time Factors; Transplantation, Homologous; Viral Matrix Proteins; Viremia | 2001 |
Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients.
Topics: Adult; Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Female; Ganciclovir; Humans; Illinois; Immunization, Passive; Lung Transplantation; Male; Middle Aged; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Predictive Value of Tests; Prospective Studies; Reagent Kits, Diagnostic; Sensitivity and Specificity; Survival Analysis; Syndrome; Viral Load | 2001 |
Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance.
Topics: Antiviral Agents; Bone Marrow Transplantation; Cerebral Ventricles; Child; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Combinations; Drug Resistance, Viral; Encephalitis, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds | 2001 |
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2001 |
Efficacy of cidofovir on human herpesvirus 8 viraemia and Kaposi's sarcoma progression in two patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Disease Progression; DNA, Viral; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi; Skin Neoplasms; Treatment Outcome; Viremia | 2001 |
Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Fluorescent Dyes; Fundulidae; In Vitro Techniques; Kidney Tubules, Proximal; Membrane Transport Proteins; Microscopy, Confocal; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents; Xenobiotics | 2001 |
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Antiviral Agents; Bowen's Disease; Cidofovir; Cytosine; Homosexuality, Male; Humans; Male; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Penile Neoplasms; Skin Neoplasms; Tumor Virus Infections | 2001 |
Bioterrorism. Blocking smallpox: a second defense.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Disease Outbreaks; Humans; Macaca fascicularis; Military Medicine; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States; Variola virus; World Health Organization | 2001 |
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Codon; Cytosine; DNA Mutational Analysis; Drug Resistance, Viral; Female; Foscarnet; Graft vs Host Disease; Herpes Simplex; Humans; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Point Mutation; Salvage Therapy; Simplexvirus; Thymidine Kinase; Transplantation, Homologous; Valacyclovir; Valine; Viral Proteins; Virus Activation | 2001 |
Antiviral prophylaxis with twice daily topical cidofovir protects against challenge in the adenovirus type 5/New Zealand rabbit ocular model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Cultivation; Virus Replication | 2001 |
Cidofovir.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds | 2001 |
Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Division; Cidofovir; Cytosine; Epithelial Cells; Growth Inhibitors; Herpesvirus 4, Human; Humans; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Organophosphonates; Organophosphorus Compounds; Tenofovir; Xenograft Model Antitumor Assays | 2001 |
Anti-CD20 monoclonal antibody (Rituximab) and Cidofovir as successful treatment of an EBV-associated lymphoma with CNS involvement.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; B-Lymphocytes; Cidofovir; Cytosine; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Lymphoid; Lymph Nodes; Lymphoproliferative Disorders; Meninges; Organophosphonates; Organophosphorus Compounds; Prognosis; Rituximab | 2001 |
Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells.
Topics: Annexin A5; Antiviral Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cell Line; Cell Nucleus; Cells, Cultured; Cidofovir; Cytosine; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Keratinocytes; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Phosphatidylserines; Proto-Oncogene Proteins p21(ras); S Phase; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2000 |
Cidofovir treatment of progressive multifocal leukoencephalopathy in a patient receiving highly active antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.
Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis | 2001 |
Cidofovir for KS lesions.
Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Herpesvirus 8, Human; HIV Infections; Humans; Italy; Male; Organophosphonates; Organophosphorus Compounds; Sarcoma, Kaposi | 2001 |
Cidofovir-induced end-stage renal failure.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Kidney Failure, Chronic; Male; Organophosphonates; Organophosphorus Compounds | 2002 |
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation | 2001 |
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting | 2001 |
Acute renal failure in a lung transplant patient after therapy with cidofovir.
Topics: Acute Kidney Injury; Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Lung Transplantation; Male; Organophosphonates; Organophosphorus Compounds | 2001 |
Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Deoxyepinephrine; Dexamethasone; Dopamine Agonists; Drug Therapy, Combination; Glucocorticoids; Humans; Intraocular Pressure; Ocular Hypotension; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior | 2001 |
Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Deoxyepinephrine; Dexamethasone; Dopamine Agonists; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Intraocular Pressure; Ocular Hypotension; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior | 2001 |
Drugs for non-HIV viral infections.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine | 2002 |
Cidofovir: progress in the treatment of progressive multifocal encephalopathy (PML)?
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Disease Progression; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds; Viral Load | 2002 |
Smallpox eradication: destruction of variola virus stocks.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Macaca fascicularis; Mice; Models, Animal; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Public Health; Sequence Analysis, DNA; Smallpox; Smallpox Vaccine; Variola virus; World Health Organization | 2002 |
Resolution of recurrent perianal condylomata acuminata by topical cidofovir in patients with HIV infection.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence; Severity of Illness Index; Skin Diseases, Viral; Treatment Outcome | 2001 |
Compounding of topical cidofovir.
Topics: Administration, Topical; Cidofovir; Cytosine; Drug Compounding; Organophosphonates; Organophosphorus Compounds; Solutions | 2002 |
[Progressive multifocal leukoencephalopathy revealing AIDS in a 13-year-old girl].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cerebrospinal Fluid; Cidofovir; Cytosine; Female; HIV Seropositivity; Humans; Infectious Disease Transmission, Vertical; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prognosis; Time Factors | 2002 |
Topical use of cidofovir induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Topical; Adult; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Condylomata Acuminata; Cytosine; Humans; Kidney Failure, Chronic; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Treatment Failure; Treatment Outcome | 2002 |
Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.
Topics: Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Coloring Agents; Cyclization; Cytosine; Esters; Fibroblasts; Humans; Indicators and Reagents; Neutral Red; Nucleotides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Vero Cells; Viral Plaque Assay; Virus Replication | 2002 |
Orally available cidofovir derivative active against smallpox.
Topics: Administration, Oral; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox | 2002 |
Polymerase chain reaction-based "pre-emptive" therapy with cidofovir for cytomegalovirus reactivation in allogeneic hematopoietic stem cells transplantation recipients: a prospective study.
Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prospective Studies; Virus Activation | 2002 |
Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers.
Topics: Animals; Antiviral Agents; Carcinoma; Cell Division; Cidofovir; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Oncogene Proteins, Viral; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Radiation-Sensitizing Agents; Radiation, Ionizing; Retinoblastoma Protein; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Virus Infections; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2002 |
Characterization of wild-type and cidofovir-resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses.
Topics: 3T3 Cells; Animals; Antiviral Agents; Camelus; Cattle; Chlorocebus aethiops; Cidofovir; Cowpox virus; Cytosine; Drug Resistance, Viral; Mice; Mice, Inbred BALB C; Mice, SCID; Microbial Sensitivity Tests; Monkeypox virus; Organophosphonates; Organophosphorus Compounds; Poxviridae; Poxviridae Infections; Vaccinia virus; Vero Cells; Viral Plaque Assay; Virus Replication | 2002 |
Transcriptional downregulation of ORF50/Rta by methotrexate inhibits the switch of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 from latency to lytic replication.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cidofovir; Cytosine; Down-Regulation; Drug Resistance; Foscarnet; Herpesvirus 8, Human; Humans; Immediate-Early Proteins; Interleukin-6; Methotrexate; Neuropeptides; Nucleic Acid Synthesis Inhibitors; Open Reading Frames; Organophosphonates; Organophosphorus Compounds; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Viral Proteins; Virus Activation; Virus Latency; Virus Replication | 2002 |
Local treatment of HPV-induced skin lesions by Cidofovir.
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Treatment Outcome; Warts | 2002 |
Treatment of aerosolized cowpox virus infection in mice with aerosolized cidofovir.
Topics: Administration, Inhalation; Aerosols; Animals; Antiviral Agents; Body Weight; Bronchopneumonia; Cidofovir; Cowpox; Cowpox virus; Cytosine; Female; Injections, Subcutaneous; Lung; Mice; Mice, Inbred BALB C; Organ Size; Organophosphonates; Organophosphorus Compounds; Statistics, Nonparametric | 2002 |
Treatment of lethal cowpox virus respiratory infections in mice with 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine and its orally active diacetate ester prodrug.
Topics: Animals; Antiviral Agents; Area Under Curve; Body Weight; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred BALB C; Nasal Mucosa; Organophosphonates; Organophosphorus Compounds; Prodrugs; Purines; Statistics, Nonparametric; Vero Cells | 2002 |
Oral drug and old vaccine renew smallpox bioterror debate.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Contraindications; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States | 2002 |
Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo.
Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cell Adhesion; Cell Line; Chelating Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Ethylenediamines; Herpesviridae Infections; Humans; Intercellular Adhesion Molecule-1; Jurkat Cells; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Succinates; Virus Replication | 2002 |
A case of flare syndrome.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine | 2001 |
Office-based treatment of laryngeal papillomatosis with percutaneous injection of cidofovir.
Topics: Adult; Ambulatory Care; Antineoplastic Agents; Cidofovir; Cytosine; Female; Follow-Up Studies; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Retrospective Studies; Sampling Studies; Severity of Illness Index; Treatment Outcome | 2002 |
In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs.
Topics: Adenoviridae; Antiviral Agents; Aphidicolin; Cidofovir; Cytomegalovirus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Herpesvirus 1, Human; Humans; Indicators and Reagents; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2002 |
Determination of cidofovir in both skin layers and percutaneous penetration samples by HPLC.
Topics: Antiviral Agents; Calibration; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Humans; Hydrogen-Ion Concentration; Organophosphonates; Organophosphorus Compounds; Permeability; Reproducibility of Results; Sensitivity and Specificity; Skin; Skin Absorption; Spectrophotometry, Ultraviolet | 2002 |
Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient.
Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Fissure in Ano; Herpes Simplex; Herpesvirus 2, Human; Humans; Organophosphonates; Organophosphorus Compounds | 2002 |
Antiviral therapy for cytomegalovirus infections in pediatric patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Infant; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Time Factors | 2002 |
Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro.
Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Fibroblasts; Guinea Pigs; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Liposomes; Mice; Organophosphonates; Organophosphorus Compounds; Rats; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication | 2002 |
Gearing up for smallpox.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Humans; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States; Variola virus | 2002 |
Anti-cancer agents. Will cidofovir be useful against cervical lesions?
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Uterine Cervical Dysplasia | 2000 |
Successful treatment of squamous cell carcinoma of the lower eyelid with intralesional cidofovir.
Topics: Aged; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Cidofovir; Cytosine; Eyelid Neoplasms; Humans; Injections, Intralesional; Male; Organophosphonates; Organophosphorus Compounds | 2002 |
The smallpox vaccine and postvaccinal encephalitis.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Bioterrorism; Cidofovir; Contraindications; Cytosine; Encephalomyelitis, Acute Disseminated; Female; gamma-Globulins; History, 19th Century; History, 20th Century; Humans; Male; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; Vaccination | 2002 |
Topical cidofovir for erythroplasia of Queyrat of the glans penis.
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Erythroplasia; Humans; Male; Organophosphonates; Organophosphorus Compounds; Penile Neoplasms | 2002 |
Optimization of topical cidofovir penetration using microparticles.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Delayed-Action Preparations; Drug Compounding; Ear, External; In Vitro Techniques; Lactic Acid; Microspheres; Organophosphonates; Organophosphorus Compounds; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Skin Absorption; Solvents; Swine | 2002 |
Smallpox--eradicated, but a growing terror threat.
Topics: Antiviral Agents; Biological Warfare; Bioterrorism; Cidofovir; Cytosine; Europe; History, 16th Century; History, 18th Century; History, 20th Century; History, Ancient; History, Medieval; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; USSR | 2002 |
Treatment of conjunctival squamous cell carcinoma with topical cidofovir.
Topics: Antineoplastic Agents; Biopsy; Carcinoma, Squamous Cell; Cidofovir; Conjunctival Neoplasms; Cytosine; Female; Humans; Middle Aged; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds | 2002 |
Sequence changes in the human adenovirus type 5 DNA polymerase associated with resistance to the broad spectrum antiviral cidofovir.
Topics: Adenoviruses, Human; Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Genetic Variation; Humans; Molecular Sequence Data; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA; Viral Plaque Assay | 2002 |
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine | 2002 |
Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient.
Topics: Adenoviridae; Adenoviridae Infections; Alanine Transaminase; Antiviral Agents; Blood; Child; Cidofovir; Cytosine; DNA, Viral; Female; Humans; Immunocompromised Host; Liver Transplantation; Organophosphonates; Organophosphorus Compounds | 2002 |
Treatment of polyomavirus infection with cidofovir in a renal-transplant recipient.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Injections, Intravenous; Kidney Transplantation; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Tumor Virus Infections | 2002 |
Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain.
Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Blotting, Western; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Herpesvirus 1, Human; Molecular Sequence Data; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA; Thymidine Kinase; Vero Cells; Viral Plaque Assay | 2002 |
Successful treatment of varicella zoster virus retinitis with aggressive intravitreal and systemic antiviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Foscarnet; Ganciclovir; Herpes Zoster Ophthalmicus; Humans; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Retinitis; Vitreous Body | 2002 |
Public health. Treating vaccine reactions: two lifelines, but no guarantees.
Topics: Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Encephalomyelitis, Acute Disseminated; Humans; Immunization, Passive; Immunoglobulins; Kaposi Varicelliform Eruption; Mice; Organophosphonates; Organophosphorus Compounds; Risk Factors; Smallpox Vaccine; Vaccinia; Vaccinia virus | 2002 |
A pilot study of cidofovir in patients with kaposi sarcoma.
Topics: Adult; Aged; Antiviral Agents; Cidofovir; Cytosine; Humans; Interleukin-6; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Sarcoma, Kaposi; Skin; Viral Load | 2003 |
Hypotony after intravenous cidofovir therapy for the treatment of cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Atrophy; Child; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Humans; Infusions, Intravenous; Intraocular Pressure; Male; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Ultrasonography | 2002 |
Quantitative viral load monitoring and cidofovir therapy for the management of BK virus-associated nephropathy in children and adults.
Topics: Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Kidney Diseases; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Prospective Studies; Tumor Virus Infections; Viral Load | 2003 |
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice.
Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Topical; Animals; Antiviral Agents; Azepines; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Permeability; Skin Absorption | 2003 |
Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism.
Topics: Antiviral Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Cidofovir; Cytosine; Fibroblasts; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Radiopharmaceuticals | 2003 |
BK nephropathy: what is the role of antiviral therapy?
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Graft Rejection; Humans; Immunocompromised Host; Kidney Transplantation; Nephritis; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections; Viral Load; Virus Replication | 2003 |
Treatment of refractory BK virus-associated nephropathy with cidofovir.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Creatinine; Cytosine; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; Hispanic or Latino; Humans; Immunosuppression Therapy; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Nephritis; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections; Viral Load; White People | 2003 |
Smallpox vaccination and adverse reactions. Guidance for clinicians.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antiviral Agents; Central Nervous System Diseases; Child; Child, Preschool; Cidofovir; Contraindications; Cross Infection; Cytosine; Disease Transmission, Infectious; Drugs, Investigational; Eye Infections; Female; Fetal Diseases; Humans; Hypersensitivity; Immunocompromised Host; Immunoglobulins, Intravenous; Immunologic Tests; Infant; Infection Control; Infectious Disease Transmission, Vertical; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pregnancy; Risk Factors; Skin Diseases, Eczematous; Skin Diseases, Vesiculobullous; Smallpox Vaccine; Vaccination; Vaccinia | 2003 |
Correlation between cidofovir-associated uveitis and failing immunorestoration during HAART.
Topics: Acquired Immunodeficiency Syndrome; Adult; Analysis of Variance; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cidofovir; Cohort Studies; Confidence Intervals; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunity; Immunocompromised Host; Infusions, Intravenous; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probability; Recovery of Function; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Uveitis, Anterior | 2003 |
Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation.
Topics: Adenovirus Infections, Human; Adolescent; Adult; Antiviral Agents; Bone Marrow Transplantation; Child; Child, Preschool; Cidofovir; Cytosine; Data Collection; Europe; Hematopoietic Stem Cell Transplantation; Humans; Infant; Organophosphonates; Organophosphorus Compounds; Surveys and Questionnaires; Transplantation, Homologous | 2003 |
Prolonged survival in AIDS-related progressive multifocal leucoencephalopathy following anti-retroviral therapy and cidofovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cerebrospinal Fluid; Cidofovir; Cytosine; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Survival Rate; Treatment Outcome | 2003 |
BK transplant nephropathy successfully treated with cidofovir.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Humans; Kidney Transplantation; Male; Middle Aged; Nephritis, Interstitial; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Tumor Virus Infections | 2003 |
Regression of a cutaneous melanoma metastasis after intralesional cidofovir.
Topics: Antineoplastic Agents; Cidofovir; Cytosine; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Organophosphonates; Organophosphorus Compounds; Remission Induction; Skin Neoplasms; Time Factors; Treatment Outcome | 2003 |
Cidofovir and surgery for genital warts.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Combined Modality Therapy; Condylomata Acuminata; Cytosine; Female; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds | 2002 |
Antiviral agent cidofovir decreases Epstein-Barr virus (EBV) oncoproteins and enhances the radiosensitivity in EBV-related malignancies.
Topics: Animals; Antiviral Agents; Apoptosis; bcl-2-Associated X Protein; Burkitt Lymphoma; Carcinoma; Caspase 3; Caspase 9; Caspases; Cell Division; Cidofovir; Combined Modality Therapy; Cytosine; Enzyme Activation; Epstein-Barr Virus Infections; Female; Gene Expression Regulation, Viral; Genes, bcl-2; Herpesvirus 4, Human; Humans; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Oncogene Proteins, Viral; Organophosphonates; Organophosphorus Compounds; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Remission Induction; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Virus Infections; Viral Matrix Proteins; Xenograft Model Antitumor Assays | 2003 |
[Anti-viral injectable treatment (cidofovir) in laryngeal papillomatosis].
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Laser Therapy; Male; Middle Aged; Neoadjuvant Therapy; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Prospective Studies; Treatment Outcome; Tumor Virus Infections | 2002 |
Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds | 2003 |
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds | 2003 |
[Antiviral effect of sulfated sialyl lipid against a clinical strain of adenovirus].
Topics: Adenoviridae; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Humans; Lipids; N-Acetylneuraminic Acid; Organophosphonates; Organophosphorus Compounds; Zalcitabine | 2003 |
Alpha interferon augments cidofovir's antiviral and antiproliferative activities.
Topics: Antiviral Agents; Blotting, Western; Cell Line, Transformed; Cidofovir; Colony Count, Microbial; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Drug Synergism; Humans; Interferon-alpha; Keratinocytes; Oncogene Proteins, Viral; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus E7 Proteins; Papillomavirus Infections; Repressor Proteins; Retinoblastoma Protein; Tumor Suppressor Protein p53; Tumor Virus Infections | 2003 |
Progressive multifocal leukoencephalopathy: cidofovir therapy in three patients with underlying hematological disease.
Topics: Aged; Cidofovir; Cytosine; Hematologic Diseases; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Middle Aged; Organophosphonates; Organophosphorus Compounds; Patients | 2003 |
Comparative effects of cidofovir and cyclic HPMPC on lethal cowpox and vaccinia virus respiratory infections in mice.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cidofovir; Cowpox; Cytosine; Female; Infusions, Parenteral; Liver; Lung Diseases; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Vaccinia | 2003 |
Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.
Topics: Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Poxviridae Infections; Prodrugs; Skin; Tenofovir; Virus Replication | 2003 |
Intralesional cidofovir for the treatment of severe juvenile recurrent respiratory papillomatosis: long-term results in 4 children.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomaviridae; Papillomavirus Infections; Prospective Studies; Recurrence; Tumor Virus Infections | 2003 |
Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR.
Topics: Antiviral Agents; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Regression Analysis | 2003 |
Topical cidofovir (HPMPC) is an effective adjuvant to surgical treatment of anogenital condylomata acuminata.
Topics: Administration, Topical; Adult; Antiviral Agents; Anus Diseases; Chemotherapy, Adjuvant; Chi-Square Distribution; Cidofovir; Condylomata Acuminata; Cytosine; Electrocoagulation; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Organophosphonates; Organophosphorus Compounds | 2003 |
Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Humans; Injections, Intralesional; Laryngoscopy; Laser Therapy; Male; Organophosphonates; Organophosphorus Compounds; Papilloma; Prospective Studies; Respiratory Tract Neoplasms; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome | 2003 |
Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Cidofovir; Cytosine; Esterification; Esters; Female; Kidney; Mice; Organophosphonates; Organophosphorus Compounds; Radiopharmaceuticals; Tissue Distribution | 2003 |
HPMPC therapy of MCMV-induced retinal disease in the SCID mouse measured by electroretinography, a non-invasive technique.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Female; Herpesviridae Infections; Humans; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Retina; Treatment Outcome; Virus Replication | 2003 |
Aerosolized cidofovir is retained in the respiratory tract and protects mice against intranasal cowpox virus challenge.
Topics: Administration, Intranasal; Aerosols; Animals; Antiviral Agents; Cidofovir; Cowpox; Cowpox virus; Cytosine; Female; Injections, Subcutaneous; Kidney; Lung; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Respiratory System; Tissue Distribution | 2003 |
Establishment and cidofovir sensitivity of a cell line from a heart transplant recipient with multiple cutaneous tumors.
Topics: Aged; Antiviral Agents; Biopsy; Cell Division; Chromosome Aberrations; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Neoplasm; Heart Transplantation; Herpesvirus 4, Human; Humans; Immunoenzyme Techniques; Karyotyping; Keratinocytes; Male; Organophosphonates; Organophosphorus Compounds; Skin Neoplasms; Tumor Cells, Cultured | 2003 |
Multicentric Castleman's disease treated with antivirals and immunosuppressants.
Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antiviral Agents; Castleman Disease; Chlorambucil; Cidofovir; Cytosine; Drug Therapy, Combination; Foscarnet; Herpesvirus 8, Human; Humans; Immunosuppressive Agents; Male; Organophosphonates; Organophosphorus Compounds; Prednisolone; Sarcoma, Kaposi; Treatment Outcome | 2003 |
BK virus nephropathy diagnosis and treatment: experience at the University of Maryland Renal Transplant Program.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Maryland; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Postoperative Complications; Retrospective Studies; Transplantation, Homologous | 2002 |
Long-term follow-up of pediatric recurrent respiratory papillomatosis managed with intralesional cidofovir.
Topics: Airway Obstruction; Antiviral Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Male; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma | 2003 |
[Bilateral uveitis with definitive hypotony caused by systemic cidofovir].
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Humans; Injections, Intravenous; Male; Middle Aged; Necrosis; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior | 2003 |
Efficacy of multiple- or single-dose cidofovir against vaccinia and cowpox virus infections in mice.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Viral; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vaccinia; Vero Cells | 2003 |
Effect of anti-cytomegalovirus therapy on the incidence of immune recovery uveitis in AIDS patients with healed cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Epiretinal Membrane; Eye Diseases; Female; Humans; Incidence; Macular Edema; Male; Organophosphonates; Organophosphorus Compounds; Risk Factors; Uveitis; Vitreous Body | 2003 |
Successful cidofovir treatment of adenovirus-associated hemorrhagic cystitis and renal dysfunction after allogenic bone marrow transplant.
Topics: Acute Kidney Injury; Adenoviridae; Adenoviridae Infections; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Hematuria; Humans; Male; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Assessment; Transplantation, Homologous; Treatment Outcome | 2003 |
[Intralesional cidofovir injections for recurrent laryngeal papillomatosis: first results].
Topics: Adolescent; Adult; Aged; Airway Obstruction; Antiviral Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Drug Administration Schedule; Female; Humans; Inclusion Bodies, Viral; Injections, Intralesional; Laryngeal Neoplasms; Larynx; Laser Therapy; Male; Microscopy, Electron; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Organophosphorus Compounds; Papilloma; Pilot Projects; Prospective Studies; Treatment Outcome | 2003 |
Local and systemic effects of intralaryngeal injection of cidofovir in a canine model.
Topics: Animals; Antiviral Agents; Atrophy; Blood Urea Nitrogen; Cidofovir; Creatinine; Cytosine; Dogs; Dose-Response Relationship, Drug; Injections, Intramuscular; Kidney; Laryngeal Edema; Laryngeal Muscles; Larynx; Leukocytes; Necrosis; Organophosphonates; Organophosphorus Compounds; Vocal Cords | 2003 |
Treatment of orf poxvirus lesion with cidofovir cream.
Topics: Administration, Topical; Animals; Antiviral Agents; Child; Cidofovir; Cytosine; Ecthyma, Contagious; Female; Hand Dermatoses; Humans; Orf virus; Organophosphonates; Organophosphorus Compounds; Sheep | 2003 |
Topical cidofovir for condylomata acuminata of the genitalia in a 3-year-old child.
Topics: Antiviral Agents; Child, Preschool; Cidofovir; Condylomata Acuminata; Cytosine; Genital Diseases, Male; Humans; Male; Ointments; Organophosphonates; Organophosphorus Compounds | 2003 |
Optimization of recombinant vaccinia-based ELISPOT assay.
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Survival; Cidofovir; Cytosine; Enzyme-Linked Immunosorbent Assay; Female; Interferon-gamma; Mice; Mice, Inbred C57BL; Organophosphonates; Organophosphorus Compounds; Pan troglodytes; Recombinant Proteins; Sensitivity and Specificity; Vaccinia virus; Virus Replication | 2003 |
Intralesional cidofovir and surgical excision for laryngeal papillomatosis.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papilloma; Treatment Outcome | 2003 |
Boom, or bust?
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Animals; Bacterial Vaccines; Biomedical Research; Bioterrorism; Cidofovir; Cytosine; Federal Government; Humans; Influenza Vaccines; Organophosphonates; Organophosphorus Compounds; Research Personnel; Research Support as Topic; Smallpox; United States | 2003 |
The cotton rat model for adenovirus ocular infection: antiviral activity of cidofovir.
Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antigens, Viral; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cornea; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Eye Infections, Viral; Female; Organophosphonates; Organophosphorus Compounds; Rats; Sigmodontinae; Viral Plaque Assay; Virus Replication; Virus Shedding | 2004 |
Real-time blood plasma polymerase chain reaction for management of disseminated adenovirus infection.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Monitoring; Humans; Infant; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Viral Load | 2004 |
A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values.
Topics: Child; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Monkeypox virus; Organophosphonates; Organophosphorus Compounds; Poxviridae Infections; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2003 |
Intravenous cidofovir for recalcitrant verruca vulgaris in the setting of HIV.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Hand Dermatoses; Humans; Infusions, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Warts | 2004 |
Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response.
Topics: Antigens, Viral; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Immunity, Cellular; Lung; Lung Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 2004 |
Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Cidofovir; Cowpox; Cowpox virus; Cytosine; Ethers; Female; Lipids; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Vaccinia; Vaccinia virus; Viral Load; Virus Replication | 2004 |
[Ocular hypotonia in leukemia].
Topics: Antineoplastic Agents; Cidofovir; Cytosine; Diagnosis, Differential; Humans; Leukemia, B-Cell; Male; Middle Aged; Ocular Hypertension; Organophosphonates; Organophosphorus Compounds; Uveitis, Anterior | 2004 |
Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Ectromelia virus; Ectromelia, Infectious; Esters; Female; Inhibitory Concentration 50; Mice; Molecular Structure; Organophosphonates; Organophosphorus Compounds | 2004 |
Topical cidofovir and cryotherapy--combination treatment for recalcitrant molluscum contagiosum in a patient with HIV infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cryotherapy; Cytosine; Humans; Male; Molluscum Contagiosum; Organophosphonates; Organophosphorus Compounds | 2004 |
Use of cidofovir in polyomavirus BK viral nephropathy in two renal allograft recipients.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polyomavirus Infections; Transplantation, Homologous; Tumor Virus Infections | 2003 |
Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; Female; Foscarnet; Ganciclovir; Humans; Lymphoma, T-Cell; Molecular Epidemiology; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA | 2004 |
Progressive multifocal leukoencephalopathy successfully treated with highly active antiretroviral therapy and cidofovir in an adolescent infected with perinatal human immunodeficiency virus (HIV).
Topics: Adolescent; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Diagnosis, Differential; Follow-Up Studies; HIV Infections; HIV-1; Humans; Image Enhancement; Infectious Disease Transmission, Vertical; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Neurologic Examination; Neuropsychological Tests; Organophosphonates; Organophosphorus Compounds; Treatment Outcome; Viral Load | 2004 |
Intravenous ribavirin for eradication of respiratory syncytial virus (RSV) and adenovirus isolates from the respiratory and/or gastrointestinal tract in recipients of allogeneic hematopoietic stem cell transplants.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Adult; Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Gastrointestinal Tract; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory System; Ribavirin; Treatment Outcome | 2004 |
[Infection due to acyclovir-resistant varicella-zoster herpes virus in a patient with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fatal Outcome; Female; Foscarnet; Herpes Zoster; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Organophosphonates | 2004 |
The management of oral human papillomavirus with topical cidofovir: a case report.
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Differential; Gels; HIV Infections; Humans; Male; Mouth Diseases; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections | 2004 |
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication | 2004 |
Inhibitory activity of alkoxyalkyl and alkyl esters of cidofovir and cyclic cidofovir against orthopoxvirus replication in vitro.
Topics: Alkylation; Antiviral Agents; Cidofovir; Cowpox virus; Cyclization; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Structure-Activity Relationship; Vaccinia virus; Viral Plaque Assay; Virus Replication | 2004 |
Susceptibility of porcine cytomegalovirus to antiviral drugs.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA, Viral; Fluorescent Antibody Technique, Indirect; Foscarnet; Ganciclovir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Swine; Virus Replication | 2004 |
Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice.
Topics: Animals; Antiviral Agents; Body Weight; Brain; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Heart; Liver; Lung; Mice; Mice, Inbred BALB C; Organophosphonates; Oxygen; Purines; Respiratory Tract Infections; Ribavirin; Salivary Glands; Spleen; Treatment Outcome; Vaccinia; Vaccinia virus; Viral Plaque Assay; Viremia | 2004 |
Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction | 2004 |
Efficacy of cidofovir in a murine model of disseminated progressive vaccinia.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Mice; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Skin; Vaccinia; Vaccinia virus | 2004 |
Failure of cidofovir in HIV-associated multicentric Castleman disease.
Topics: Anti-HIV Agents; Castleman Disease; Cidofovir; Cytosine; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Treatment Failure | 2004 |
Current treatment for laryngeal papillomatosis.
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Laser Therapy; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomavirus Infections; Treatment Outcome | 2004 |
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins | 2004 |
Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir.
Topics: Administration, Cutaneous; Animals; Antiviral Agents; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Mice; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Vaccinia; Vaccinia virus | 2004 |
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication | 2004 |
Successful treatment of human herpesvirus 6 encephalomyelitis in immunocompetent patient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Encephalomyelitis; Female; Ganciclovir; Herpesvirus 6, Human; Humans; Immunocompetence; Organophosphonates; Organophosphorus Compounds; Roseolovirus Infections | 2004 |
Cidofovir plasma assays after local injection in respiratory papillomatosis.
Topics: Adult; Aged; Antiviral Agents; Area Under Curve; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Female; Humans; Infant; Injections, Intralesional; Larynx; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Prospective Studies | 2004 |
Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Esters; Ether; Humans; Lipids; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Prodrugs; Treatment Outcome | 2004 |
Perianal ulcer in a patient with AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Diagnosis, Differential; Fatal Outcome; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Perineum; Skin Ulcer | 2004 |
Topical cidofovir is more effective than is parenteral therapy for treatment of progressive vaccinia in immunocompromised mice.
Topics: Administration, Topical; Animals; Antiviral Agents; Brain; Cidofovir; Cyclophosphamide; Cytosine; Disease Models, Animal; Female; Immunocompromised Host; Immunosuppressive Agents; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin; Specific Pathogen-Free Organisms; Spleen; Survival Analysis; Time Factors; Vaccinia; Viral Plaque Assay | 2004 |
Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esters; Female; Injections, Intraperitoneal; Injections, Intravenous; Lipids; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Structure-Activity Relationship; Viral Load | 2004 |
American Society of Pediatric Otolaryngology members' experience with recurrent respiratory papillomatosis and the use of adjuvant therapy.
Topics: Antineoplastic Agents; Antiviral Agents; Australia; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Cytosine; Debridement; Europe; Health Care Surveys; Humans; Laryngeal Neoplasms; Microsurgery; Neoplasm Recurrence, Local; North America; Organophosphonates; Organophosphorus Compounds; Papilloma; Respiratory Tract Neoplasms | 2004 |
Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cidofovir; Cohort Studies; Cytosine; Female; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome | 2004 |
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication | 2004 |
Cidofovir on HHV-8 in BCBL-1 cells.
Topics: Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; DNA, Viral; Herpesvirus 8, Human; Humans; Organophosphonates; Virion; Virus Replication | 2004 |
Intralesional cidofovir for pediatric recurrent respiratory papillomatosis.
Topics: Antineoplastic Agents; Child; Child, Preschool; Cidofovir; Cytosine; Debridement; Female; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Retrospective Studies; Treatment Outcome | 2004 |
Unanimous vote approves tweak to smallpox genome.
Topics: Cidofovir; Cytosine; Drug Evaluation, Preclinical; Genes, Reporter; Genetic Engineering; Genome, Viral; Humans; Organophosphonates; Smallpox; Smallpox Vaccine; Variola virus; World Health Organization | 2004 |
Serial office-based intralesional injection of cidofovir in adult-onset recurrent respiratory papillomatosis.
Topics: Adult; Ambulatory Care; Antineoplastic Agents; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2004 |
Dissection of the Kaposi's sarcoma-associated herpesvirus gene expression program by using the viral DNA replication inhibitor cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA Replication; DNA, Viral; Gene Expression Profiling; Gene Expression Regulation, Viral; Herpesvirus 8, Human; Humans; Oligonucleotide Array Sequence Analysis; Open Reading Frames; Organophosphonates; Viral Proteins; Virus Replication | 2004 |
Efficacy of cidofovir injection for the treatment of recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Treatment Outcome | 2004 |
Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis.
Topics: Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Indoles; Injections, Intralesional; Injections, Intravenous; Lung Neoplasms; Organophosphonates; Papilloma; Probenecid | 2005 |
Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient.
Topics: Adenoviridae; Adenovirus Infections, Human; Administration, Intravesical; Adult; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; Hemorrhage; Humans; Male; Organophosphonates | 2005 |
Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity?
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dideoxynucleosides; Encephalitis; False Negative Reactions; Fatal Outcome; Humans; Immunocompromised Host; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Substance Abuse, Intravenous; Time Factors; Virus Activation; Zidovudine | 2004 |
Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Esters; Ether; Humans; Lipids; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Prodrugs; Virus Replication | 2005 |
Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro.
Topics: Animals; Anti-HIV Agents; Cells, Cultured; Cidofovir; Coloring Agents; Cytomegalovirus; Cytosine; Esters; Ethylene Glycols; Glycerol; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Neutral Red; Organophosphonates; Propylene Glycols; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication | 2005 |
Treatment of herpesvirus associated primary effusion lymphoma with intracavity cidofovir.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cidofovir; Cytosine; Herpesvirus 8, Human; Humans; Injections, Intralesional; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Organophosphonates; Remission Induction; Time Factors | 2005 |
Effect of leflunomide and cidofovir on replication of BK virus in an in vitro culture system.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Isoxazoles; Leflunomide; Organophosphonates; Virus Replication | 2005 |
Successful treatment of a refractory verruca in a child with acute lymphoblastic leukaemia with topical cidofovir.
Topics: Antiviral Agents; Child; Cidofovir; Cytosine; Female; Foot Dermatoses; Humans; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Warts | 2005 |
Delivery of cidofovir to respiratory papillomas of the distal trachea.
Topics: Antineoplastic Agents; Bronchoscopes; Child, Preschool; Cidofovir; Cytosine; Humans; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Tracheal Neoplasms | 2005 |
Stability of cidofovir in extemporaneously prepared syringes.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Stability; Drug Storage; Hydrogen-Ion Concentration; Organophosphonates; Osmolar Concentration; Syringes | 2005 |
[Cidofovir activity in infantile recurrent respiratory papillomatosis].
Topics: Antiviral Agents; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Laryngeal Neoplasms; Laser Therapy; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2005 |
Tubular cell apoptosis and cidofovir-induced acute renal failure.
Topics: Acute Kidney Injury; Adult; Annexin A5; Antiviral Agents; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cidofovir; Cytomegalovirus Retinitis; Cytosine; HIV Infections; Humans; Kidney Tubules, Proximal; Male; Organophosphonates | 2005 |
Effects of cidofovir on cell death and replication of feline herpesvirus-1 in cultured feline corneal epithelial cells.
Topics: Animals; Antiviral Agents; Cats; Cell Culture Techniques; Cell Death; Cell Survival; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; DNA, Viral; Epithelium, Corneal; Herpesviridae; Immunohistochemistry; Keratin-3; Keratins; Organophosphonates; Polymerase Chain Reaction; Virus Replication | 2005 |
High anti-double-stranded DNA antibodies and progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus.
Topics: Antibodies, Anti-Idiotypic; Cidofovir; Cytosine; Disease Progression; DNA; Fatal Outcome; Female; Humans; Immunocompromised Host; JC Virus; Leukoencephalopathy, Progressive Multifocal; Lupus Erythematosus, Systemic; Middle Aged; Organophosphonates | 2005 |
The efficacy of cidofovir treatment of mice infected with ectromelia (mousepox) virus encoding interleukin-4.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Ectromelia virus; Ectromelia, Infectious; Interleukin-4; Mice; Mice, Inbred C57BL; Organophosphonates | 2005 |
Refractory human papillomavirus-associated oral warts treated topically with 1-3% cidofovir solutions in human immunodeficiency virus type 1-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; HIV-1; Humans; Male; Middle Aged; Mouth Diseases; Organophosphonates; Papillomaviridae; Warts | 2005 |
Antiviral activity of Cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity.
Topics: Adult; Antiviral Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Survival; Cidofovir; Cytosine; Head and Neck Neoplasms; Humans; Male; Neoplasm Proteins; Oncogene Proteins, Viral; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Radiation Tolerance; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2005 |
Ribonucleotide reductase inhibitors enhance cidofovir-induced apoptosis in EBV-positive nasopharyngeal carcinoma xenografts.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Interactions; Enzyme Inhibitors; Epstein-Barr Virus Infections; Humans; Hydroxamic Acids; Hydroxyurea; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Organophosphonates; Ribonucleotide Reductases; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
In vitro susceptibility of adenovirus to antiviral drugs is species-dependent.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; Drug Resistance, Viral; Humans; Microbial Sensitivity Tests; Organophosphonates; Ribavirin; Species Specificity | 2005 |
[BK virus infection in a child after an hematopoietic stem cell transplantation].
Topics: Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Organophosphonates; Polyomavirus Infections; Prognosis | 2005 |
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).
Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA; Genetic Variation; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Organic Anion Transport Protein 1; Organophosphonates; p-Aminohippuric Acid; Polymorphism, Single Nucleotide; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Complementary; Tenofovir; Xenopus laevis | 2005 |
Human herpesvirus-8-related Kaposi's sarcoma after liver transplantation successfully treated with cidofovir and liposomal daunorubicin.
Topics: Antibiotics, Antineoplastic; Antiviral Agents; Cidofovir; Cytosine; Daunorubicin; Drug Therapy, Combination; Herpesvirus 8, Human; Humans; Immunocompromised Host; Liver Transplantation; Male; Middle Aged; Organophosphonates; Sarcoma, Kaposi; Viral Load; Viremia | 2005 |
Adjuvant low-dose cidofovir therapy for BK polyomavirus interstitial nephritis in renal transplant recipients.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections | 2005 |
Characterization and treatment of cidofovir-resistant vaccinia (WR strain) virus infections in cell culture and in mice.
Topics: Animals; Cells, Cultured; Cidofovir; Cytosine; Disease Models, Animal; Drug Resistance; Mice; Mice, Inbred BALB C; Mice, SCID; Mutation; Organophosphonates; Vaccinia; Vaccinia virus; Virus Replication | 2005 |
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication | 2005 |
Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate.
Topics: Antiviral Agents; Cidofovir; Cytosine; Diphosphates; DNA Primers; DNA-Directed DNA Polymerase; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Substrate Specificity | 2005 |
Development of herpes simplex virus disease in patients who are receiving cidofovir.
Topics: Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Humans; Male; Organophosphonates; Simplexvirus | 2005 |
Thyrohyoid approach to cidofovir injection: a case study.
Topics: Antineoplastic Agents; Cidofovir; Cytosine; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Treatment Outcome | 2005 |
Remission of progressive multifocal leucoencephalopathy in SLE after treatment with cidofovir: a 4 year follow up.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Follow-Up Studies; Humans; Leukoencephalopathy, Progressive Multifocal; Lupus Erythematosus, Systemic; Organophosphonates; Treatment Outcome | 2005 |
Dramatic improvement in non-AIDS related progressive multifocal leucoencephalopathy.
Topics: Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Hematologic Diseases; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2005 |
Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro.
Topics: Antiviral Agents; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Cidofovir; Cyclization; Cytomegalovirus; Cytosine; Enzyme-Linked Immunosorbent Assay; Esters; Fibroblasts; Flow Cytometry; Herpesviridae; Humans; In Situ Hybridization; Organophosphonates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication | 2005 |
Cidofovir for cytomegalovirus reactivation in pediatric patients after hematopoietic stem cell transplantation.
Topics: Adolescent; Antigens, Viral; Antiviral Agents; Child; Cidofovir; Creatinine; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Premedication; Virus Activation | 2005 |
Polyoma virus nephropathy in native kidneys after lung transplantation.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cisplatin; Cytosine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Lung Transplantation; Male; Mycophenolic Acid; Neoplasm Metastasis; Organophosphonates; Polyomavirus; Polyomavirus Infections; Seminoma; Steroids; Tacrolimus | 2005 |
Cidofovir for recurrent respiratory papillomatosis (RRP): a re-assessment of risks.
Topics: Animals; Antiviral Agents; Carcinogens; Child; Cidofovir; Cytosine; Drug Approval; Humans; Neoplasm Recurrence, Local; Organophosphonates; Papillomavirus Infections; Respiratory Tract Neoplasms; Risk Assessment; Severity of Illness Index; United States; United States Food and Drug Administration | 2005 |
Incidence, clinical outcome, and management of virus-induced hemorrhagic cystitis in children and adolescents after allogeneic hematopoietic cell transplantation.
Topics: Adenoviridae; Adolescent; Adult; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Disease Management; DNA, Viral; Female; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Incidence; Infant; JC Virus; Male; Mass Screening; Organophosphonates; Polyomavirus; Prospective Studies; Risk Factors; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Viruses | 2005 |
Fatal HHV-6 associated encephalitis in an HIV-1 infected patient treated with cidofovir.
Topics: Antiviral Agents; Biopsy; Brain; Cidofovir; Cytosine; Encephalitis, Viral; Fatal Outcome; Female; Herpesvirus 6, Human; HIV Infections; HIV-1; Humans; Magnetic Resonance Imaging; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Roseolovirus Infections; Viral Load | 2006 |
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cidofovir; Cytosine; HIV Infections; Humans; Mice; Mice, Nude; Models, Chemical; Moloney murine sarcoma virus; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Poxviridae; Poxviridae Infections; Purines; Pyrimidines; Vaccinia; Vaccinia virus | 2005 |
Histopathologic effects of cidofovir on cartilage.
Topics: Animals; Biopsy, Needle; Cartilage; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear, External; Female; Immunohistochemistry; Injections, Subcutaneous; Linear Models; Logistic Models; Male; Models, Animal; Organophosphonates; Rabbits; Sensitivity and Specificity | 2005 |
Activities of acyclic nucleoside phosphonates against Orf virus in human and ovine cell monolayers and organotypic ovine raft cultures.
Topics: Adenine; Animals; Cell Line; Cell Line, Transformed; Cidofovir; Cytosine; Humans; Keratinocytes; Nucleosides; Orf virus; Organophosphonates; Organophosphorus Compounds; Sheep | 2005 |
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure.
Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Molecular Sequence Data; Mutation; Organophosphonates | 2005 |
Inhibition of the replication of DNA viruses by phosphonylmethoxyalkyl-purines and -pyrimidines.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Viruses; Organophosphonates; Simplexvirus; Virus Replication | 1989 |
Treatment of recurrent respiratory papillomatosis with microsurgery in combination with intralesional cidofovir--a prospective study.
Topics: Antineoplastic Agents; Cidofovir; Combined Modality Therapy; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Diseases; Male; Microsurgery; Organophosphonates; Papilloma; Prospective Studies; Recurrence; Treatment Outcome | 2006 |
Successful cidofovir therapy of progressive multifocal leukoencephalopathy preceding angioimmunoblastic T-cell lymphoma.
Topics: Cidofovir; Cytosine; Diagnosis, Differential; Humans; Immunoblastic Lymphadenopathy; Leukoencephalopathy, Progressive Multifocal; Lymphoma, T-Cell; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Organophosphonates; Treatment Outcome | 2005 |
Cidofovir and the black box warning.
Topics: Animals; Antineoplastic Agents; Cidofovir; Cytosine; Disease Progression; Drug Labeling; Humans; Laryngeal Neoplasms; Neoplasms; Organophosphonates; Papilloma; Rats | 2005 |
Case of progressive dysplasia concomitant with intralesional cidofovir administration for recurrent respiratory papillomatosis.
Topics: Adult; Antineoplastic Agents; Cidofovir; Cytosine; Disease Progression; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2005 |
Cidofovir incorporation into human keratinocytes with episomal HPV 16 results in nonselective cytotoxicity.
Topics: Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Genes, Viral; Human papillomavirus 16; Humans; Keratinocytes; Organophosphonates; Plasmids; Tumor Cells, Cultured | 2005 |
British Association of Paediatric Otorhinolaryngology members experience with recurrent respiratory papillomatosis.
Topics: Anticarcinogenic Agents; Antiviral Agents; Child; Cidofovir; Cytosine; Databases, Factual; Health Care Surveys; Human papillomavirus 11; Human papillomavirus 6; Humans; Indoles; Interferons; Laryngeal Neoplasms; Laser Therapy; Neoplasm Recurrence, Local; Organophosphonates; Otolaryngology; Papilloma; Papillomavirus Infections; Pediatrics; Practice Patterns, Physicians'; United Kingdom | 2006 |
A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.
Topics: Animals; Antiviral Agents; Cidofovir; Codon, Terminator; Cytosine; Genes, Viral; Herpesvirus Vaccines; Humans; Lung; Mice; Mice, Inbred C57BL; Mutation; Organophosphonates; Rhadinovirus; Trans-Activators; Vaccination; Viral Proteins; Virus Latency | 2006 |
Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro.
Topics: Antineoplastic Agents; Cell Proliferation; Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Esters; Female; Fibroblasts; HeLa Cells; Humans; Organophosphonates; Papillomavirus Infections; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2006 |
Intravenous cidofovir treatment for recalcitrant warts in the setting of a patient with myelodysplastic syndrome.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Differential; Female; Hand; Humans; Infusions, Intravenous; Myelodysplastic Syndromes; Organophosphonates; Skin Diseases; Warts | 2006 |
Cidofovir treatment of HIV-associated cytomegalovirus polyradiculopathy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Female; Humans; Organophosphonates; Polyradiculopathy | 2006 |
Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Child; Cidofovir; Contraindications; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Transplantation; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Transplantation, Homologous; Tumor Virus Infections; Uricosuric Agents | 2006 |
Disseminated adenovirus infection with respiratory failure in pediatric liver transplant recipients: impact of intravenous cidofovir and inhaled nitric oxide.
Topics: Adenovirus Infections, Human; Administration, Inhalation; Antiviral Agents; Biliary Atresia; Cidofovir; Cytosine; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Immunosuppression Therapy; Infant; Liver Failure, Acute; Liver Transplantation; Nitric Oxide; Organophosphonates; Postoperative Complications; Respiratory Insufficiency | 2006 |
Cyclic cidofovir (cHPMPC) prevents congenital cytomegalovirus infection in a guinea pig model.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Infectious Disease Transmission, Vertical; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Roseolovirus; Roseolovirus Infections | 2006 |
Progressive multifocal leukoencephalopathy: prolonged survival in patients treated with protease inhibitors and cidofovir: a case series.
Topics: Adolescent; Adult; Anti-HIV Agents; Brain; Cidofovir; Cytosine; Female; HIV Protease Inhibitors; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Survival Rate | 2006 |
Ether lipid ester derivatives of cidofovir inhibit polyomavirus BK replication in vitro.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Esters; Organophosphonates; Virus Replication | 2006 |
Natural history of adult-onset laryngeal papillomatosis following multiple cidofovir injections.
Topics: Adult; Antiviral Agents; Biopsy; Cidofovir; Cytosine; DNA, Viral; Female; Follow-Up Studies; Human papillomavirus 6; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Organophosphonates; Papilloma; Papillomavirus Infections; Prospective Studies; Time Factors; Treatment Outcome | 2006 |
Risk of immune recovery uveitis in patients with AIDS and cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cross-Sectional Studies; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Injections; Male; Organophosphonates; Prevalence; Risk Factors; Uveitis, Posterior; Visual Acuity; Vitreous Body | 2006 |
Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy (PVAN).
Topics: Adult; Antiviral Agents; Biopsy; Cidofovir; Cyclosporine; Cytosine; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Postoperative Complications; Treatment Outcome | 2006 |
N-chlorotaurine is an effective antiviral agent against adenovirus in vitro and in the Ad5/NZW rabbit ocular model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Infections, Viral; Female; Keratitis; Ophthalmic Solutions; Organophosphonates; Rabbits; Taurine; Viral Plaque Assay; Virus Replication | 2006 |
Viral mRNA expression but not DNA replication is required for lipogenic effect of human adenovirus Ad-36 in preadipocytes.
Topics: 3T3-L1 Cells; Adenovirus E1A Proteins; Adenovirus E4 Proteins; Adenoviruses, Human; Adipocytes; Adipogenesis; Animals; Antiviral Agents; CCAAT-Enhancer-Binding Protein-beta; Cidofovir; Cytosine; DNA Replication; DNA, Viral; Gene Expression; Genes, Viral; Humans; Mice; Obesity; Organophosphonates; RNA, Viral | 2007 |
Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Infant; Male; Organophosphonates; Recurrence; Retrospective Studies; Risk Factors | 2006 |
Cidofovir bladder instillation for the treatment of BK hemorrhagic cystitis after allogeneic stem cell transplantation.
Topics: Administration, Intravesical; Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hemorrhage; Humans; Male; Organophosphonates; Platelet Transfusion; Polyomavirus Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Stem Cell Transplantation; Transplantation, Homologous; Viral Load | 2006 |
A non-chemotherapy treatment of a primary effusion lymphoma: durable remission after intracavitary cidofovir in HIV negative PEL refractory to chemotherapy.
Topics: Aged; Antineoplastic Agents; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; HIV Seronegativity; Humans; Immunophenotyping; Lymphoma; Male; Organophosphonates; Remission Induction | 2006 |
Effects of cidofovir treatment on cytokine induction in murine models of cowpox and vaccinia virus infection.
Topics: Animals; Antiviral Agents; Cidofovir; Cowpox; Cytokines; Cytosine; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred BALB C; Organophosphonates; Vaccinia; Vaccinia virus | 2006 |
The effect of cidofovir on cytomegalovirus-induced hearing loss in a Guinea pig model.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Evoked Potentials, Auditory; Guinea Pigs; Hearing Loss; Organophosphonates; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures.
Topics: Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cyclization; Cytopathogenic Effect, Viral; Cytosine; Esters; Fibroblasts; Humans; Keratinocytes; Organophosphonates; Orthopoxvirus | 2006 |
Effect of local application of cidofovir on the control of recurrences in recurrent laryngeal papillomatosis.
Topics: Adult; Antineoplastic Agents; Cidofovir; Cytosine; Follow-Up Studies; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organophosphonates; Papilloma; Treatment Outcome; Video Recording | 2006 |
Office-based intralesional cidofovir injections for nasal septal papilloma: a pilot study.
Topics: Adult; Antineoplastic Agents; Cidofovir; Cytosine; Follow-Up Studies; Humans; Injections, Intralesional; Male; Middle Aged; Nasal Septum; Nose Neoplasms; Organophosphonates; Outpatients; Papilloma | 2006 |
[Pure alexia secondary to progressive multifocal leukoencephalopathy as first manifestation of HIV infection].
Topics: Alexia, Pure; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Cidofovir; Cytosine; HIV Infections; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates | 2006 |
Is intralesional cidofovir worthwhile in juvenile recurrent respiratory papillomatosis?
Topics: Adjuvants, Pharmaceutic; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Drug Administration Schedule; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Prospective Studies; Treatment Outcome | 2006 |
Remission of AIDS-associated progressive multifocal leukoencephalopathy with combined cidofovir and radiotherapy: a case report.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates | 2006 |
Chronic hypertrophic acyclovir-resistant genital herpes treated with topical cidofovir and with topical foscarnet at recurrence in an HIV-positive man.
Topics: Acyclovir; Administration, Topical; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Herpes Genitalis; HIV Infections; Humans; Male; Middle Aged; Organophosphonates | 2006 |
Intravenous cidofovir-induced resolution of disfiguring cutaneous human papillomavirus infection.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Injections, Intravenous; Male; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Treatment Outcome | 2006 |
Encapsulation of antiviral nucleotide analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules.
Topics: Anti-HIV Agents; Capsules; Chromatography, High Pressure Liquid; Cidofovir; Cyanoacrylates; Cytosine; Drug Compounding; Enbucrilate; Freeze Drying; Microscopy, Electron, Scanning; Organophosphonates; Particle Size; Polymers; Zidovudine | 2006 |
Maribavir sensitivity of cytomegalovirus isolates resistant to ganciclovir, cidofovir or foscarnet.
Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Viral Proteins | 2006 |
Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice.
Topics: Alleles; Animals; Base Sequence; Biomarkers; Cell Line; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Recombinant; Drug Resistance, Viral; Genome, Viral; Genotype; Humans; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Organophosphonates; Phenotype; Protein Structure, Quaternary; Vaccinia virus; Virulence | 2006 |
Mutations in the E9L polymerase gene of cidofovir-resistant vaccinia virus strain WR are associated with the drug resistance phenotype.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Genes, Viral; Mice; Mice, Inbred BALB C; Mutation; Organophosphonates; Phenotype; Specific Pathogen-Free Organisms; Vaccinia; Vaccinia virus; Vero Cells | 2006 |
Cidofovir administered with radiation displays an antiangiogenic effect mediated by E6 inhibition and subsequent TP53-dependent VEGF repression in HPV18+ cell lines.
Topics: Angiogenic Proteins; Antineoplastic Agents; Cell Line, Tumor; Cidofovir; Cytosine; Down-Regulation; Female; Humans; Neovascularization, Pathologic; Organophosphonates; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2006 |
CR12/339--Nebulized cidofovir for recurrent respiratory papillomatosis: a case report.
Topics: Administration, Inhalation; Antineoplastic Agents; Cidofovir; Cytosine; Female; Follow-Up Studies; Humans; Infant; Laryngeal Neoplasms; Nebulizers and Vaporizers; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2006 |
Synergistic combination effect of cidofovir and idoxuridine on vaccinia virus replication.
Topics: Animals; Antiviral Agents; Cell Line; Chick Embryo; Cidofovir; Cytosine; Drug Synergism; Drug Therapy, Combination; Idoxuridine; Organophosphonates; Vaccinia virus; Virus Replication | 2006 |
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Multiple; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2007 |
Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Hepacivirus; Hepatitis B virus; HIV; Humans; Organophosphonates; Papillomaviridae; Poxviridae; Tenofovir; Virus Diseases; Viruses | 2007 |
Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Ecthyma, Contagious; Orf virus; Organophosphonates; Paraffin; Sheep; Silicic Acid | 2007 |
Progressive multifocal leukoencephalopathy mimicking cerebral vasculitis in systemic granulomatosis.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Cerebrospinal Fluid; Cidofovir; Cytarabine; Cytosine; Diagnosis, Differential; DNA, Viral; Fatal Outcome; Hemiplegia; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Polymerase Chain Reaction; Tuberculosis; Vasculitis, Central Nervous System | 2007 |
Intralesional Cidofovir application in recurrent laryngeal papillomatosis.
Topics: Adult; Aged; Antiviral Agents; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Female; Human papillomavirus 11; Human papillomavirus 6; Humans; Laryngeal Mucosa; Laryngeal Neoplasms; Laser Therapy; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organophosphonates; Papilloma; Remission Induction | 2007 |
Anterior uveitis associated with treatment with intravenous cidofovir in kidney transplant patients with BK virus nephropathy.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Cidofovir; Creatinine; Cytosine; Female; Graft Survival; Humans; Infusions, Intravenous; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Postoperative Complications; Retrospective Studies; Tumor Virus Infections; Uveitis, Anterior | 2006 |
Oral 1-O-octadecyl-2-O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice.
Topics: Administration, Oral; Animals; Cidofovir; Cytosine; Ectromelia virus; Ectromelia, Infectious; Female; Liver; Lung; Mice; Organophosphonates; Respiratory Tract Infections | 2007 |
Encapsulation of mono- and oligo-nucleotides into aqueous-core nanocapsules in presence of various water-soluble polymers.
Topics: Cations; Chitosan; Cidofovir; Cyanoacrylates; Cytosine; Dideoxynucleotides; Drug Carriers; Enbucrilate; Materials Testing; Nanocapsules; Nucleotides; Oligonucleotides; Organophosphonates; Permeability; Polyethyleneimine; Polymers; Solubility; Thymine Nucleotides; Water; Zidovudine | 2007 |
The nucleotide analog cidofovir suppresses basic fibroblast growth factor (FGF2) expression and signaling and induces apoptosis in FGF2-overexpressing endothelial cells.
Topics: Animals; Antiviral Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Cidofovir; Cytochromes c; Cytosine; Endothelial Cells; Fibroblast Growth Factor 2; Mice; Organophosphonates; Poly(ADP-ribose) Polymerases; Signal Transduction; Tumor Suppressor Protein p53 | 2007 |
Cidofovir is effective against caprine herpesvirus 1 infection in goats.
Topics: Animals; Cidofovir; Cytosine; Disease Models, Animal; Goats; Herpesviridae Infections; Organophosphonates; Varicellovirus; Virus Shedding | 2007 |
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir.
Topics: Amino Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Cell Survival; Cidofovir; Cytosine; Ethylene Glycol; Half-Life; Humans; Hydrolysis; KB Cells; Magnetic Resonance Spectroscopy; Organophosphonates; Peptide Transporter 1; Phenylalanine; Prodrugs; Rats; Symporters; Valine; Viral Plaque Assay | 2007 |
Utilization of vero cells for primary and chronic BK virus infection.
Topics: Animals; Antiviral Agents; BK Virus; Child; Chlorocebus aethiops; Cidofovir; Cytosine; Humans; Models, Biological; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections; Vero Cells | 2006 |
In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ecthyma, Contagious; Fibroblasts; Humans; In Vitro Techniques; Keratinocytes; Lung; Nucleosides; Orf virus; Organophosphonates; Prodrugs; Sensitivity and Specificity; Sheep | 2007 |
[Intravesical cidofovir--instillation therapy for polyomavirus-associated hemorrhagic cystitis after bone marrow transplantation].
Topics: Administration, Intravesical; Adolescent; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; Hematuria; Humans; Immunosuppressive Agents; Male; Opportunistic Infections; Organophosphonates; Polyomavirus Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Therapeutic Irrigation | 2007 |
A case of 'red eye' post allogeneic stem cell transplantation.
Topics: Adenoviridae; Adenovirus Infections, Human; Adult; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Transplantation, Homologous | 2007 |
Effects of cidofovir on a novel cell-based test system for recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Blotting, Western; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Flow Cytometry; Human papillomavirus 16; Human papillomavirus 6; Humans; Organophosphonates; Otorhinolaryngologic Neoplasms; Papillomavirus Infections; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2007 |
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates | 2007 |
Fatal adenovirus hepatitis during maintenance therapy for childhood acute lymphoblastic leukemia.
Topics: Adenovirus Infections, Human; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Asparaginase; Child, Preschool; Cidofovir; Computer Systems; Cytosine; DNA, Viral; Fatal Outcome; Hepatitis, Viral, Human; Humans; Immunocompromised Host; Male; Mercaptopurine; Methotrexate; Multiple Organ Failure; Organophosphonates; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine; Viremia | 2008 |
Improved outcome from invasive adenovirus infection in pediatric patients after hemopoietic stem cell transplantation using intensive clinical surveillance and early intervention.
Topics: Adenovirus Infections, Human; Adolescent; Antiviral Agents; Blood; Bronchoalveolar Lavage Fluid; Child; Cidofovir; Cytosine; Feces; Female; Fluorescent Antibody Technique; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Immunosuppression Therapy; Infant; Male; Microscopy, Electron, Transmission; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin | 2007 |
Improvement of progressive multifocal leukoencephalopathy after cidofovir therapy in a patient with a destructive polyarthritis.
Topics: Aged; Antibodies, Viral; Antiviral Agents; Arthritis; Brain; Cidofovir; Cytosine; Female; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates; Radiography; Treatment Outcome | 2007 |
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA Viruses; Humans; Mice; Organophosphonates; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Triazines | 2007 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Fatal Outcome; Ganciclovir; Hodgkin Disease; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Renal Insufficiency; Secondary Prevention; Treatment Failure; Virus Activation | 2007 |
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cowpox; Cytomegalovirus Infections; Cytosine; Herpes Simplex; HIV-1; Humans; In Vitro Techniques; Molecular Structure; Organophosphonates; Sensitivity and Specificity; Vaccinia | 2007 |
Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Humans; Kidney; Kinetics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Organophosphonates; Probenecid; Tenofovir; Transfection | 2007 |
Human immunodeficiency virus-associated progressive multifocal leucoencephalopathy: epidemiology and predictive factors for prolonged survival.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cidofovir; Cytosine; Female; HIV Infections; Humans; Immunocompromised Host; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Prognosis; Retrospective Studies; Survival Analysis | 2007 |
Progressive multifocal leucoencephalopathy in a patient with sarcoidosis--successful treatment with cidofovir and mirtazapine.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Mianserin; Middle Aged; Mirtazapine; Opportunistic Infections; Organophosphonates; Sarcoidosis | 2007 |
Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.
Topics: Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Mice; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Polyomavirus; Pyrimidine Nucleosides; Pyrimidines; Simian virus 40 | 2007 |
Low-dose cidofovir treatment of BK virus-associated hemorrhagic cystitis in recipients of hematopoietic stem cell transplant.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Medical Records; Middle Aged; Organophosphonates; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections | 2007 |
Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir.
Topics: Adenovirus Infections, Human; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Lymphocyte Depletion; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; T-Lymphocytes | 2007 |
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
Topics: Acyclovir; Adolescent; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2007 |
Ureteric and urethral stenosis: a complication of BK virus infection in a pediatric renal transplant patient.
Topics: Adolescent; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cystoscopy; Cytosine; Diagnosis, Differential; DNA, Viral; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Kidney Failure, Chronic; Kidney Transplantation; Male; Microscopy, Electron; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Tumor Virus Infections; Ureteral Obstruction; Urethral Stricture | 2007 |
Simultaneous development of Fanconi syndrome and acute renal failure associated with cidofovir.
Topics: Acute Kidney Injury; Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Fanconi Syndrome; Humans; Male; Organophosphonates | 2007 |
Cidofovir and foscarnet for treatment of human herpesvirus 6 encephalitis in a neutropenic stem cell transplant recipient.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Foscarnet; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Herpesvirus 6, Human; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Organophosphonates; Roseolovirus Infections; Viral Load | 2007 |
In vivo imaging of cidofovir treatment of cowpox virus infection.
Topics: Animals; Antiviral Agents; Bioterrorism; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; DNA Replication; Drug Evaluation, Preclinical; Female; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Organophosphonates; Recombination, Genetic; Smallpox; Treatment Outcome; Vero Cells; Virus Replication | 2007 |
[Progressive multifocal leukoencephalopathy in a non-AIDS patient: high efficiency of combined cytarabine and cidofovir].
Topics: Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Lupus Erythematosus, Systemic; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome | 2007 |
Treatment of lentigo maligna with topical 1% cidofovir.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cidofovir; Cytosine; Facial Neoplasms; Female; Humans; Hutchinson's Melanotic Freckle; Organophosphonates; Skin Neoplasms | 2007 |
Oral topical cidofovir: novel route of drug delivery in a severely immunosuppressed patient with refractory multidrug-resistant herpes simplex virus infection.
Topics: Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Herpesvirus 1, Human; Humans; Immunocompromised Host; Middle Aged; Mouthwashes; Organophosphonates; Stem Cell Transplantation; Stomatitis, Herpetic | 2007 |
Adenovirus-associated hemorrhagic cystitis in a pediatric renal transplant recipient.
Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Child, Preschool; Cidofovir; Cystitis; Cytosine; DNA, Viral; Follow-Up Studies; Hematuria; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Organophosphonates; Polymerase Chain Reaction; Postoperative Complications | 2007 |
Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Injections, Intraperitoneal; Mice; Organophosphonates; Survival Analysis; Thymidine; Vaccinia; Vaccinia virus; Viral Plaque Assay | 2007 |
A model of human cytomegalovirus infection in severe combined immunodeficient mice.
Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay | 2007 |
Rabbitpox virus and vaccinia virus infection of rabbits as a model for human smallpox.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Vaccinia; Vaccinia virus; Viremia | 2007 |
Viral-associated trichodysplasia in a patient with lymphoma: a case report and review.
Topics: Administration, Topical; Aged; Alopecia; Antiviral Agents; Cidofovir; Cytosine; Facial Dermatoses; Hair Diseases; Hair Follicle; Humans; Inclusion Bodies, Viral; Intranuclear Inclusion Bodies; Lymphoma, Non-Hodgkin; Male; Organophosphonates; Polyomavirus; Treatment Outcome | 2007 |
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Genotype; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Models, Molecular; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Phenotype; Protein Binding; Protein Conformation; Vero Cells; Viral Proteins; Virulence | 2007 |
Efficacy of topical immunoglobulins against experimental adenoviral ocular infection.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cell Culture Techniques; Cidofovir; Conjunctiva; Cornea; Cytosine; Disease Models, Animal; Epithelial Cells; Eye Infections, Viral; Flow Cytometry; Immunoglobulins, Intravenous; Immunologic Factors; Keratoconjunctivitis; Organophosphonates; Rabbits; Treatment Outcome; Virus Cultivation; Virus Replication; Virus Shedding | 2007 |
Treatment of adenovirus pneumonia with cidofovir in pediatric lung transplant recipients.
Topics: Adenovirus Infections, Human; Antiviral Agents; Child, Preschool; Cidofovir; Community-Acquired Infections; Cytosine; Humans; Immunocompromised Host; Infant; Lung Transplantation; Organophosphonates; Pneumonia, Viral | 2007 |
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Male; Mice; Microscopy, Electron, Transmission; Nucleosides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Swiss 3T3 Cells; Virus Replication | 2007 |
Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Ectromelia virus; Ectromelia, Infectious; Ether; Female; Hepatocytes; Humans; Mice; Mice, Inbred A; Organophosphonates | 2008 |
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Combinations; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Hydroxyurea; Mutation; Organophosphonates; Ribonucleotide Reductases; Thymidine Kinase | 2008 |
Potent inhibition of genital herpesvirus infection in goats by cidofovir.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Goats; Herpes Genitalis; Herpesviridae Infections; Organophosphonates; Varicellovirus | 2007 |
Case report: severe gastrointestinal inflammation and persistent HHV-6B infection in a paediatric cancer patient.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; Astrocytoma; Cidofovir; Cytosine; Diarrhea; Drug Therapy, Combination; Gastrointestinal Diseases; Herpesvirus 6, Human; Humans; Immunosuppression Therapy; Infant; Inflammation; Male; Organophosphonates; Prednisolone; Roseolovirus Infections; Treatment Outcome | 2007 |
Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Ribonucleosides; Sequence Alignment; Viral Proteins | 2008 |
Progressive multifocal leukoencephalopathy as first manifestation of sarcoidosis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Sarcoidosis | 2008 |
Identification of adenoviruses in specimens from high-risk pediatric stem cell transplant recipients and controls.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Animals; Cell Line; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Genotype; Humans; Infant; Macaca mulatta; Organophosphonates; Prospective Studies; Sequence Analysis, DNA; Stem Cell Transplantation; Transplantation; Virus Cultivation | 2008 |
Cidofovir diphosphate inhibits molluscum contagiosum virus DNA polymerase activity.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Humans; Molluscum Contagiosum; Molluscum contagiosum virus; Organophosphonates | 2008 |
Successful outcome of a disseminated adenovirus infection 6 years after allogeneic bone marrow transplantation.
Topics: Adenovirus Infections, Human; Adult; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Lymphopenia; Male; Organophosphonates; Survivors; Time Factors; Transplantation, Homologous | 2008 |
Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Templates, Genetic; Vaccinia virus; Virus Replication | 2008 |
Some novel aminopropyl nucleoside phosphonates.
Topics: Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; Humans; Nucleosides; Organophosphonates; Propylamines | 2007 |
Quantification of cidofovir in human serum by LC-MS/MS for children.
Topics: Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Humans; Molecular Structure; Organophosphonates; Reproducibility of Results; Tandem Mass Spectrometry | 2008 |
Chlorpromazine combined with cidofovir for treatment of a patient suffering from progressive multifocal leukoencephalopathy.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Brain; Chlorpromazine; Cidofovir; Cytosine; DNA, Viral; Drug Therapy, Combination; Fatal Outcome; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Organophosphonates | 2007 |
Cidofovir in combination with HAART and survival in AIDS-associated progressive multifocal leukoencephalopathy.
Topics: Adult; AIDS Dementia Complex; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytosine; Drug Combinations; Female; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Retrospective Studies; Survival Rate; Treatment Outcome | 2008 |
Differential pathogenesis of cowpox virus intranasal infections in mice induced by low and high inoculum volumes and effects of cidofovir treatment.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Body Weight; Chemokines; Cidofovir; Cowpox; Cowpox virus; Cytokines; Cytosine; Female; Giant Cells; Lung; Mice; Mice, Inbred BALB C; Organ Size; Organophosphonates | 2008 |
1% topical cidofovir used as last alternative to treat viral infections.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Molluscum Contagiosum; Organophosphonates; Papillomavirus Infections | 2008 |
Characterization of a cidofovir-resistant HHV-6 mutant obtained by in vitro selection.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Cidofovir; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Herpesvirus 6, Human; Inhibitory Concentration 50; Molecular Sequence Data; Mutation, Missense; Organophosphonates; Viral Proteins; Virus Replication | 2008 |
Recovery of humoral immunity is critical for successful antiviral therapy in disseminated mouse adenovirus type 1 infection.
Topics: 3T3 Cells; Adenoviridae; Adenoviridae Infections; Animals; Antibodies, Viral; Antiviral Agents; Cell Line; Cidofovir; Cyclophosphamide; Cytosine; Disease Models, Animal; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, SCID; Organophosphonates; Treatment Outcome | 2008 |
Biopsy-proven adenoviral diarrhea responding to low-dose cidofovir.
Topics: Adenoviridae; Adenovirus Infections, Human; Aged; Antigens, Viral; Antiviral Agents; Biopsy; Cidofovir; Cytosine; Dexamethasone; Diarrhea; Drug Administration Schedule; Feces; Gastric Mucosa; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Inclusion Bodies, Viral; Intranuclear Inclusion Bodies; Male; Multiple Myeloma; Organophosphonates; Thalidomide; Treatment Outcome | 2008 |
High-risk adenovirus-infected pediatric allogeneic hematopoietic progenitor cell transplant recipients and preemptive cidofovir therapy.
Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Case-Control Studies; Child; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Prospective Studies; Risk Factors; Transplantation, Homologous | 2008 |
[Diagnosis of interstitial nephropathy caused by BK virus in renal transplantation. Therapeutic management with cidofovir plus probenecid].
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Kidney Transplantation; Male; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections | 2007 |
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models.
Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Mice, SCID; Muromegalovirus; Organophosphonates; Survival Analysis | 2008 |
[Treatment of pediatric genital condyloma].
Topics: Adult; Aminoquinolines; Antiviral Agents; Child; Cidofovir; Condylomata Acuminata; Cytosine; Humans; Imiquimod; Interferon Inducers; Keratinocytes; Organophosphonates; Papillomaviridae; Papillomavirus Infections | 2008 |
[Resolution of recalcitrant condyloma acuminata in a patient with human immunodeficiency virus treated with cidofovir].
Topics: Adult; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; HIV Infections; Humans; Male; Organophosphonates; Penile Diseases | 2008 |
Histologic review of cidofovir-treated recurrent respiratory papillomatosis.
Topics: Antineoplastic Agents; Child; Cidofovir; Cytosine; Humans; Laryngeal Neoplasms; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Retrospective Studies | 2008 |
Treatment of locally recurrent Epstein-Barr virus-associated nasopharyngeal carcinoma using the anti-viral agent cidofovir.
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Epstein-Barr Virus Infections; Humans; Magnetic Resonance Imaging; Male; Nasopharyngeal Neoplasms; Organophosphonates; Pharynx; Radiography; Ribosomal Proteins; RNA-Binding Proteins | 2008 |
Cidofovir injection for recurrent laryngeal papillomatosis.
Topics: Adult; Antineoplastic Agents; Child; Cidofovir; Cytosine; Female; Humans; Injections; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2008 |
BK virus-associated nephropathy in a kidney transplant recipient successfully treated with cidofovir, the first case in Japan.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Japan; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2008 |
An adenovirus type F41 outbreak in a pediatric bone marrow transplant unit: analysis of clinical impact and preventive strategies.
Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Antiviral Agents; Blood; Bone Marrow Transplantation; Capsid Proteins; Child; Child, Preschool; Cidofovir; Cross Infection; Cytosine; Disease Outbreaks; DNA, Viral; Feces; Gastroenteritis; Genotype; Germany; Hepatitis, Viral, Human; Humans; Infant; Organophosphonates; Sequence Analysis, DNA; Viral Load; Viremia; Virus Shedding | 2008 |
Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
Topics: Adenine; Anti-HIV Agents; Binding Sites; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Gene Expression Regulation, Viral; HIV Reverse Transcriptase; Models, Molecular; Molecular Structure; Organophosphonates; Protein Conformation; Tenofovir | 2008 |
A single-center experience with BK virus nephropathy.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Graft Survival; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoxazoles; Kidney Transplantation; Leflunomide; Middle Aged; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections | 2008 |
Severe eczema vaccinatum in a household contact of a smallpox vaccinee.
Topics: Antibodies, Viral; Benzamides; Child, Preschool; Cidofovir; Cytosine; Dermatitis, Atopic; DNA, Viral; Family Health; Female; Humans; Immunoglobulin G; Immunoglobulin M; Immunoglobulins, Intravenous; Isoindoles; Kaposi Varicelliform Eruption; Male; Organophosphonates; Plasma; Skin Transplantation; Smallpox Vaccine; United States | 2008 |
[Extensive oral condylomas treated by in situ cidofovir injection in an HIV patient].
Topics: Adult; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; HIV Infections; Humans; Injections, Intralesional; Male; Mouth Diseases; Organophosphonates | 2008 |
Aggressive recurrent respiratory papillomatosis in a neonate.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Cidofovir; Cytosine; ErbB Receptors; Female; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Neoplasm Recurrence, Local; Organophosphonates; Papilloma | 2008 |
Synthesis of cidofovir and (S)-HPMPA ether lipid prodrugs.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Magnetic Resonance Spectroscopy; Organophosphonates; Spectrometry, Mass, Electrospray Ionization | 2007 |
Isolation and characterization of cidofovir resistant vaccinia viruses.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Humans; Mice; Models, Molecular; Mutation; Organophosphonates; Vaccinia; Vaccinia virus; Vero Cells; Viral Plaque Assay; Virulence | 2008 |
In vitro susceptibility of sea lion poxvirus to cidofovir.
Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Kidney; Microbial Sensitivity Tests; Organophosphonates; Parapoxvirus; Poxviridae Infections; Sea Lions | 2008 |
Adult intralesional cidofovir therapy for laryngeal papilloma: a 10-year perspective.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Middle Aged; Organophosphonates; Papilloma; Recurrence; Retrospective Studies; Treatment Outcome | 2008 |
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Protein Structure, Tertiary; Viral Proteins | 2008 |
Successful cidofovir treatment in an adult heart transplant recipient with severe adenovirus pneumonia.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Extracorporeal Membrane Oxygenation; Heart Transplantation; Humans; Male; Middle Aged; Organophosphonates; Pneumonia, Viral; Severity of Illness Index; Treatment Outcome | 2008 |
Cidofovir inhibits polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression.
Topics: Antiviral Agents; BK Virus; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Humans; Kidney Tubules, Proximal; Organophosphonates; Virus Replication | 2008 |
Intermediate dose cidofovir does not cause additive nephrotoxicity in BK virus allograft nephropathy.
Topics: Adolescent; Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; Disease Progression; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; Organophosphonates; Retrospective Studies | 2008 |
Lactoferrin from bovine milk inhibits bovine herpesvirus 1 in cell culture but suppresses development of in vitro-produced bovine embryos.
Topics: Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Herpesviridae Infections; Herpesvirus 1, Bovine; Lactoferrin; Milk; Organophosphonates | 2009 |
Intralesional cidofovir does not increase the risk of laryngeal dysplasia or laryngeal carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinogenicity Tests; Carcinoma; Cidofovir; Cytosine; Humans; Infusions, Intralesional; Laryngeal Neoplasms; Organophosphonates; Rats; Teratogens | 2008 |
Cidofovir modulated gene expression in recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Cidofovir; Cytosine; Down-Regulation; Gene Expression; Humans; Interferon Regulatory Factor-7; Organophosphonates; Papilloma; Recurrence; Respiratory Tract Neoplasms; RNA, Viral; Up-Regulation | 2008 |
Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient.
Topics: Administration, Topical; Antineoplastic Agents; Cidofovir; Combined Modality Therapy; Cytosine; Endoscopy; HIV Seropositivity; Humans; Male; Middle Aged; Nose Neoplasms; Organophosphonates; Papilloma | 2009 |
Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature.
Topics: Administration, Intravesical; Adult; Antineoplastic Agents; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Hematuria; Humans; Hyperbaric Oxygenation; Leukemia, Myeloid, Acute; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2009 |
Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia.
Topics: Adenoviridae Infections; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Humans; Inhibitory Concentration 50; Organophosphonates; Pneumonia, Viral; Ribavirin; United States | 2008 |
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antiviral Agents; Base Sequence; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins; Virus Activation | 2008 |
Cidofovir in addition to antiretroviral treatment is not effective for AIDS-associated progressive multifocal leukoencephalopathy: a multicohort analysis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Agents; Antiviral Agents; Cidofovir; Cohort Studies; Cytosine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Morbidity; Odds Ratio; Organophosphonates; Proportional Hazards Models; Risk; Survival Analysis; Treatment Failure | 2008 |
Antiviral activity of cidofovir against telomerase-specific replication-selective oncolytic adenovirus, OBP-301 (Telomelysin).
Topics: Adenoviridae; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Humans; Lung Neoplasms; Oncolytic Viruses; Organophosphonates; Telomerase; Virus Replication | 2009 |
Assessing the efficacy of cidofovir against herpesvirus-induced genital lesions in goats using different therapeutic regimens.
Topics: Animals; Antiviral Agents; Base Sequence; Cidofovir; Cytosine; Disease Models, Animal; DNA Primers; DNA, Viral; Female; Genital Diseases, Female; Goat Diseases; Goats; Herpes Genitalis; Herpesviridae Infections; Humans; Organophosphonates; Species Specificity; Vaginal Creams, Foams, and Jellies; Varicellovirus | 2008 |
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; DNA Replication; DNA Viruses; DNA, Neoplasm; Drug Stability; Female; Herpesvirus 1, Human; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred Strains; Organophosphonates | 2008 |
Adenovirus infection and treatment with cidofovir in children after liver transplantation.
Topics: Adenoviridae; Adenovirus Infections, Human; Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Female; Humans; Infant; Liver Transplantation; Male; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies | 2009 |
Current treatment of polyoma BK nephropathy in pediatric renal transplant patients.
Topics: BK Virus; Child; Cidofovir; Ciprofloxacin; Cytosine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Organophosphonates; Polyomavirus | 2008 |
In vitro activity of cidofovir against the emerging Cantagalo virus and the smallpox vaccine strain IOC.
Topics: Animals; Antiviral Agents; Brazil; Cattle; Cattle Diseases; Cell Line; Chlorocebus aethiops; Cidofovir; Communicable Diseases, Emerging; Cytosine; Disease Outbreaks; Humans; Kidney; Microbial Sensitivity Tests; Organophosphonates; Smallpox Vaccine; Vaccinia; Vaccinia virus; Virus Replication; Zoonoses | 2009 |
[In vitro acyclovir and cidofovir susceptibilities of human herpesvirus type 1 clinical isolates].
Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Herpes Simplex; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Vero Cells | 2008 |
Intravenous immunoglobulin as rescue therapy for BK virus nephropathy.
Topics: Antiviral Agents; BK Virus; Child, Preschool; Cidofovir; Creatinine; Cytosine; Ganciclovir; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Kidney; Kidney Transplantation; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2009 |
Topical cidofovir for severe warts in a patient affected by AIDS and Hodgkin's lymphoma.
Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Foot; Hand; HIV Infections; Hodgkin Disease; Human papillomavirus 16; Humans; Lymphoma, AIDS-Related; Male; Organophosphonates; Papillomaviridae; Treatment Outcome; Warts | 2008 |
Results and long-term outcome in 39 patients with Wiskott-Aldrich syndrome transplanted from HLA-matched and -mismatched donors.
Topics: Antiviral Agents; Child; Child, Preschool; Chimerism; Cidofovir; Cyclosporine; Cytosine; Graft Rejection; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Infant; Living Donors; Male; Organophosphonates; Treatment Failure; Wiskott-Aldrich Syndrome | 2009 |
Pharmacodynamics of cidofovir for vaccinia virus infection in an in vitro hollow-fiber infection model system.
Topics: Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; HeLa Cells; Humans; Models, Theoretical; Monkeypox virus; Organophosphonates; Poxviridae Infections; Smallpox Vaccine | 2009 |
Experimental infection of an African dormouse (Graphiurus kelleni) with monkeypox virus.
Topics: Animal Structures; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Hemorrhage; Humans; Monkeypox virus; Mpox (monkeypox); Myoxidae; Necrosis; Organophosphonates; Smallpox Vaccine | 2009 |
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.
Topics: Adenine; Animals; Cell Line; Cell Survival; CHO Cells; Cidofovir; Cricetinae; Cricetulus; Cytosine; Guanosine; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2009 |
Coadministration of cidofovir and smallpox vaccine reduced vaccination side effects but interfered with vaccine-elicited immune responses and immunity to monkeypox.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Drug Incompatibility; Macaca fascicularis; Mpox (monkeypox); Organophosphonates; Smallpox Vaccine; T-Lymphocytes; Vaccinia | 2009 |
Treatment of BK virus-associated nephropathy with Cidofovir in renal transplantation.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Polyomavirus Infections; Tumor Virus Infections | 2008 |
A single-centre study of adjuvant cidofovir therapy for BK virus interstitial nephritis (BKVIN) in renal allograft recipients.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Male; Middle Aged; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Transplantation; Transplantation, Homologous; Tumor Virus Infections | 2009 |
Low dosage cidofovir without probenecid as treatment for BK virus hamorrhagic cystitis after hemopoietic stem cell transplant.
Topics: Adolescent; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections | 2009 |
The treatment of viral warts with topical cidofovir 1%: our experience of seven paediatric patients.
Topics: Antiviral Agents; Child; Cidofovir; Cytosine; Female; Humans; Immunocompromised Host; Male; Organophosphonates; Retrospective Studies; Warts | 2009 |
Cytomegalovirus encephalitis/retinitis in allogeneic haematopoietic stem cell transplant recipient treated successfully with combination of cidofovir and foscarnet.
Topics: Adolescent; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Encephalitis, Viral; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Organophosphonates; Retinitis; Treatment Outcome | 2009 |
Intravenous immunoglobulin as treatment for BK virus: nephropathy.
Topics: BK Virus; Cidofovir; Cytosine; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Kidney; Kidney Transplantation; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2009 |
Wiskott-Aldrich syndrome and molluscum contagiosum: a therapeutic challenge after reaction to cidofovir.
Topics: Acitretin; Adjuvants, Immunologic; Administration, Oral; Administration, Topical; Adult; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance; Humans; Imiquimod; Immunocompromised Host; Lymphoma, Large B-Cell, Diffuse; Male; Molluscum Contagiosum; Organophosphonates; Wiskott-Aldrich Syndrome | 2008 |
Intralesional injection of cidofovir for recurrent respiratory papillomatosis in children.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Infant; Injections, Intramuscular; Laryngeal Muscles; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Organophosphonates; Papilloma; Remission Induction | 2009 |
Intravesicular cidofovir for the management of BK virus-associated cystitis.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates | 2009 |
Use of cidofovir for treatment of recurrent respiratory papillomatosis.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphonates; Papilloma; Recurrence; Respiratory Tract Infections | 2009 |
The 3'-to-5' exonuclease activity of vaccinia virus DNA polymerase is essential and plays a role in promoting virus genetic recombination.
Topics: Amino Acid Sequence; Base Sequence; Biocatalysis; Cell Line; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Enzyme Activation; Exonucleases; Genes, Essential; Genetic Markers; Molecular Sequence Data; Mutation; Organophosphonates; Recombination, Genetic; Substrate Specificity; Vaccinia virus | 2009 |
Prognostic factors of recurrent respiratory papillomatosis from a registry of 72 patients.
Topics: Adult; Antineoplastic Agents; Child; Child, Preschool; Cidofovir; Cytosine; Databases, Factual; Female; France; Hospitals, Teaching; Human papillomavirus 11; Human papillomavirus 6; Humans; Laryngoscopy; Male; Organophosphonates; Papilloma; Papillomavirus Infections; Prognosis; Registries; Respiratory Tract Neoplasms; Retrospective Studies | 2009 |
Squamous cell carcinoma associated with intralesional injection of cidofovir for recurrent respiratory papillomatosis.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Child; Cidofovir; Cytosine; Female; Follow-Up Studies; Humans; Injections, Intralesional; Neoplasms, Second Primary; Organophosphonates; Otorhinolaryngologic Surgical Procedures; Papilloma; Tomography, X-Ray Computed; Trachea; Tracheal Neoplasms | 2009 |
[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection].
Topics: Agammaglobulinemia; Antiviral Agents; Azathioprine; Cidofovir; Colitis, Ulcerative; Cytomegalovirus Infections; Cytosine; Enteritis; Female; Humans; Immunization, Passive; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Leukopenia; Middle Aged; Mycophenolic Acid; Neoplasm Staging; Opportunistic Infections; Organophosphonates; Postoperative Complications; Syndrome; Thymectomy; Thymoma; Thymus Neoplasms | 2009 |
Clinical evaluation of local ocular toxicity in candidate anti-adenoviral agents in vivo.
Topics: Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Eyelids; Female; Lacrimal Apparatus; Ophthalmic Solutions; Organophosphonates; Rabbits | 2009 |
Cidofovir induces an increase in levels of low-risk and high-risk HPV E6.
Topics: Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytosine; Female; Human papillomavirus 6; Humans; Oncogene Proteins, Viral; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Transfection; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2009 |
Decreased viral load and symptoms of polyomavirus-associated chronic interstitial cystitis after intravesical cidofovir treatment.
Topics: Administration, Intravesical; Antiviral Agents; Cidofovir; Cystitis, Interstitial; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Polyomavirus; Polyomavirus Infections; Urine | 2009 |
Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.
Topics: Antiviral Agents; Cell Line; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Humans; Interferon-gamma; Organophosphonates; RNA, Small Interfering; Vaccinia virus; Viral Core Proteins; Viral Proteins; Virus Replication | 2009 |
Differential susceptibility of adenovirus clinical isolates to cidofovir and ribavirin is not related to species alone.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Genotype; Humans; Organophosphonates; Ribavirin; Serotyping; Species Specificity | 2009 |
Novel anti-metastatic action of cidofovir mediated by inhibition of E6/E7, CXCR4 and Rho/ROCK signaling in HPV tumor cells.
Topics: Alphapapillomavirus; Cell Line, Tumor; Chemokine CXCL12; Cidofovir; Cytosine; Humans; Neoplasm Metastasis; Oncogene Proteins, Viral; Organophosphonates; Papillomavirus E7 Proteins; Receptors, CXCR4; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2009 |
Progressive multifocal leukoencephalopathy following heightened immunosuppression after lung transplant.
Topics: Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Brain; Cidofovir; Cytosine; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Lung Transplantation; Magnetic Resonance Imaging; Organophosphonates; Pulmonary Fibrosis; Treatment Outcome | 2009 |
Late onset hemorrhagic cystitis in a hematopoietic stem cell recipient: treatment with intravesical hyaluronic acid.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Antiviral Agents; Child; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Hematuria; Humans; Hyaluronic Acid; Male; Organophosphonates; Postoperative Complications; Time Factors; Wiskott-Aldrich Syndrome | 2010 |
Therapeutic paint of cidofovir/sucralfate gel combination topically administered by spraying for treatment of orf virus infections.
Topics: Administration, Topical; Animals; Antiviral Agents; Chemistry, Pharmaceutical; Cidofovir; Cytosine; DNA, Viral; Ecthyma, Contagious; Excipients; Gels; Orf virus; Organophosphonates; Particle Size; Shear Strength; Sheep; Skin; Spectroscopy, Fourier Transform Infrared; Sucralfate | 2009 |
Safety and tolerability of cidofovir in high-risk pediatric patients.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kidney Diseases; Male; Organophosphonates; Treatment Outcome; Young Adult | 2009 |
What lies beneath the tent? JC-virus cerebellar granule cell neuronopathy complicating sarcoidosis.
Topics: Antiviral Agents; Cerebellar Diseases; Cerebellum; Cidofovir; Cytosine; Demyelinating Diseases; Diagnosis, Differential; Fatal Outcome; Female; Humans; Immunohistochemistry; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Middle Aged; Organophosphonates; Sarcoidosis; Steroids | 2009 |
Topical 1% cidofovir for the treatment of vulvar intraepidermal neoplasia (VIN1) developed on lichen sclerosus.
Topics: Administration, Topical; Aged; Antineoplastic Agents; Cidofovir; Cytosine; Female; Humans; Organophosphonates; Precancerous Conditions; Vulvar Lichen Sclerosus; Vulvar Neoplasms | 2009 |
Progressive multifocal leukoencephalopathy in a patient with Franklin disease and hypogammaglobulinemia.
Topics: Adenocarcinoma; Agammaglobulinemia; Aged; Antiviral Agents; Brain; Brain Neoplasms; Cidofovir; Cytosine; Diagnosis, Differential; Fatal Outcome; Heavy Chain Disease; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Paraneoplastic Syndromes; Rectal Neoplasms; Risk Factors; Virus Activation | 2009 |
Synthesis and antiviral activity evaluation of acyclic 2'-azanucleosides bearing a phosphonomethoxy function in the side chain.
Topics: Acids, Acyclic; Adenine; Antiviral Agents; Aza Compounds; Cidofovir; Cytosine; DNA Viruses; HeLa Cells; Humans; Molecular Structure; Nucleosides; Organophosphonates; RNA Viruses; Tenofovir | 2009 |
In vitro analysis of cidofovir and genetically engineered TK expression as potential approaches for the intervention of ColoAd1-based treatment of cancer.
Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Genetic Engineering; Humans; Oncolytic Virotherapy; Oncolytic Viruses; Organophosphonates; Prodrugs; Ribavirin; Thymidine Kinase; Tumor Cells, Cultured | 2009 |
The in vitro and in vivo evaluation of ddC as a topical antiviral for ocular adenovirus infections.
Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Female; Humans; Organophosphonates; Rabbits; Tumor Cells, Cultured; Viral Plaque Assay; Virus Replication; Zalcitabine | 2009 |
Cidofovir for BK virus-associated hemorrhagic cystitis: a retrospective study.
Topics: Adolescent; Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Survival Analysis; Treatment Outcome; Tumor Virus Infections; Young Adult | 2009 |
Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector.
Topics: Adenine; Anti-HIV Agents; beta-Cyclodextrins; Cidofovir; Cytosine; Electrolytes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Linear Models; Organophosphonates; Purines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tenofovir | 2009 |
Cidofovir inhibits genome encapsidation and affects morphogenesis during the replication of vaccinia virus.
Topics: Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; DNA, Viral; Morphogenesis; Organophosphonates; Vaccinia virus; Viral Proteins; Virion; Virus Assembly; Virus Replication | 2009 |
[Cidofovir gel 1% for treating papillomavirus lesions in a patient with congenital immunodeficiency].
Topics: Anemia, Hemolytic, Congenital; Antiviral Agents; Cidofovir; Cytosine; Female; Fingers; Gels; Hand Dermatoses; Humans; Organophosphonates; Papillomavirus Infections; Young Adult | 2010 |
Expansion, reexpansion, and recall-like expansion of Vgamma2Vdelta2 T cells in smallpox vaccination and monkeypox virus infection.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Interferon-gamma; Lung; Lymphocyte Activation; Macaca fascicularis; Monkeypox virus; Mpox (monkeypox); Organophosphonates; Receptors, Antigen, T-Cell, gamma-delta; Smallpox Vaccine; T-Lymphocyte Subsets; Vaccinia virus | 2009 |
Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Male; Organophosphonates; Simplexvirus; Stem Cell Transplantation; Stomatitis; Treatment Outcome | 2009 |
Disseminated adenovirus infection in renal transplant recipients: the role of cidofovir and intravenous immunoglobulin.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2010 |
A clinical algorithm identifies high risk pediatric oncology and bone marrow transplant patients likely to benefit from treatment of adenoviral infection.
Topics: Adenoviridae Infections; Algorithms; Antiviral Agents; Bone Marrow Transplantation; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; Female; Humans; Male; Organophosphonates; Retrospective Studies; Risk Factors; Transplantation, Autologous; Transplantation, Homologous | 2009 |
Persistent adenoviraemia in an infant following haematopoietic stem cell transplantation.
Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Feces; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Lymphocyte Count; Male; Mothers; Organophosphonates; Severe Combined Immunodeficiency; Viral Load; Viremia | 2010 |
Progressive multifocal leukoencephalopathy developed in incomplete Heerfordt syndrome, a rare manifestation of sarcoidosis, without steroid therapy responding to cidofovir.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Parotid Gland; Radiography; Sarcoidosis; Treatment Outcome; Uveoparotid Fever | 2010 |
Treatment results in adult-onset recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laryngoscopy; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Retrospective Studies; Young Adult | 2009 |
Potential risk factors associated with the use of cidofovir to treat benign human papillomavirus-related disease.
Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytosine; Gene Expression Profiling; Gene Expression Regulation; Humans; Off-Label Use; Organophosphonates; Papilloma; Papillomaviridae; Papillomavirus Infections; Respiratory Tract Neoplasms; Risk Factors; RNA | 2009 |
Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme.
Topics: Aminopeptidases; Antiviral Agents; Caco-2 Cells; Cidofovir; Cytosine; Humans; Kinetics; Organophosphonates; Prodrugs; Recombinant Proteins; Substrate Specificity | 2010 |
Radiofrequency coblation for treatment of advanced laryngotracheal recurrent respiratory papillomatosis.
Topics: Adult; Antineoplastic Agents; Catheter Ablation; Cidofovir; Combined Modality Therapy; Cytosine; Endoscopy; Female; Humans; Laryngeal Neoplasms; Lasers, Gas; Male; Middle Aged; Organophosphonates; Papilloma; Recurrence; Retrospective Studies; Tracheal Neoplasms; Young Adult | 2010 |
In reference to Squamous cell carcinoma associated with intralesional injection of cidofovir for recurrent respiratory papillomatosis.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cidofovir; Cytosine; Humans; Injections, Intralesional; Neoplasms, Second Primary; Organophosphonates; Papilloma; Precancerous Conditions; Tracheal Neoplasms | 2010 |
Prevalence of dysplasia in juvenile-onset recurrent respiratory papillomatosis.
Topics: Adolescent; Antineoplastic Agents; Chi-Square Distribution; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Infant; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Prevalence; Retrospective Studies; Wisconsin | 2010 |
Successful treatment of acyclovir-resistant herpes simplex virus with intralesional cidofovir.
Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Facial Dermatoses; Herpes Simplex; Humans; Injections, Intralesional; Male; Organophosphonates | 2010 |
[Medication error due to drug packaging: a case report].
Topics: Anti-HIV Agents; Cidofovir; Cytosine; Drug Packaging; Drug Prescriptions; Humans; Male; Medication Errors; Organophosphonates; Pharmacy Service, Hospital; Young Adult | 2009 |
Degrees of dysplasia and the use of cidofovir in patients with recurrent respiratory papillomatosis.
Topics: Adult; Aged; Biopsy; Cidofovir; Cytosine; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Respiratory Mucosa; Respiratory Tract Neoplasms; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2010 |
Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Mutation, Missense; Organophosphonates; Oxidation-Reduction; Sequence Analysis, DNA; Staining and Labeling; Tetrazolium Salts; Thymidine Kinase; Viral Proteins | 2010 |
Primary HHV 6 infection after liver transplantation with acute graft rejection and multi-organ failure: successful treatment with a 2.5-fold dose of cidofovir and reduction of immunosuppression.
Topics: Antiviral Agents; Child, Preschool; Cholestasis, Intrahepatic; Cidofovir; Cytosine; Female; Graft Rejection; Hepatitis; Herpesviridae Infections; Herpesvirus 6, Human; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver Cirrhosis; Liver Transplantation; Necrosis; Organophosphonates | 2011 |
Anti-adenovirus activity of epiandrosterone and dehydroepiandrosterone derivatives.
Topics: Adenoviridae; Androsterone; Animals; Antiviral Agents; Blotting, Western; Chlorocebus aethiops; Cidofovir; Cytosine; Dehydroepiandrosterone; Humans; Mice; Organophosphonates; Vero Cells; Viral Proteins; Virus Replication | 2010 |
Lack of efficacy of aurintricarboxylic acid and ethacrynic acid against vaccinia virus respiratory infections in mice.
Topics: Animals; Antiviral Agents; Aurintricarboxylic Acid; Cell Line; Cidofovir; Cytosine; Ethacrynic Acid; Mice; Mice, Inbred BALB C; Organophosphonates; Respiratory Tract Infections; Time Factors; Vaccinia; Vaccinia virus | 2010 |
Mucosal bridge and pitting of the true vocal fold: an unusual complication of cidofovir injection.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Injections, Intralesional; Laryngeal Neoplasms; Male; Mucous Membrane; Organophosphonates; Papilloma; Vocal Cords | 2010 |
Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Biological Transport; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorpromazine; Cidofovir; Cricetinae; Cytarabine; Cytosine; Humans; Immunocompetence; Mesocricetus; Neoplasms; Organ Specificity; Organophosphonates; Transduction, Genetic; Virus Replication | 2010 |
Should intralesional cidofovir be used for recurrent respiratory papillomatosis?
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Infusions, Intralesional; Organophosphonates; Papilloma; Recurrence; Respiration Disorders; Severity of Illness Index | 2010 |
Low-dose cidofovir in the treatment of symptomatic BK virus infection in patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis of an algorithmic approach.
Topics: Adult; Aged; Algorithms; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Transplantation, Homologous; Tumor Virus Infections | 2010 |
Comparative whole genome sequence analysis of wild-type and cidofovir-resistant monkeypoxvirus.
Topics: Animals; Base Sequence; Cidofovir; Cytosine; Drug Resistance, Viral; Genome, Viral; Molecular Conformation; Molecular Sequence Data; Monkeypox virus; Organophosphonates; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Viral Proteins | 2010 |
Progressive multifocal leucoencephalopathy in a patient with Sézary syndrome.
Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Cidofovir; Cytarabine; Cytosine; Fatal Outcome; Flow Cytometry; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Receptors, Antigen, T-Cell, alpha-beta; Sezary Syndrome; Skin Neoplasms | 2010 |
Intracavitary cidofovir for human herpes virus-8-associated primary effusion lymphoma in an HIV-negative patient.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cidofovir; Cyclophosphamide; Cytosine; Doxorubicin; Female; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Injections; Lymphoma, Primary Effusion; Organophosphonates; Pleural Effusion; Prednisone; Vincristine | 2010 |
Poor outcome of adenovirus infections in adult hematopoietic stem cell transplant patients with sustained adenovirus viremia.
Topics: Adenoviridae Infections; Adult; Antiviral Agents; Asymptomatic Infections; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; DNA, Viral; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; Ribavirin; Treatment Outcome; Viral Load; Viremia; Young Adult | 2010 |
Cidofovir may be deleterious in BK virus-associated nephropathy.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Graft Survival; Humans; Kidney Diseases; Kidney Transplantation; Organophosphonates; Polyomavirus Infections; Treatment Outcome; Tumor Virus Infections | 2010 |
Cidofovir-loaded liposomes: an intro-study using BCBL-1 cell line as a model for primary effusion lymphoma.
Topics: Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; Flow Cytometry; Humans; Liposomes; Lymphoma; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Organophosphonates | 2010 |
Stability of 0.5% cidofovir stored under various conditions for up to 6 months.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Stability; Drug Storage; Herpesviridae; Microbial Sensitivity Tests; Organophosphonates; Temperature; Time Factors | 2010 |
Mitochondrial changes in cidofovir therapy for BK virus nephropathy.
Topics: Adult; Aged; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cytosine; Humans; Kidney Tubules, Proximal; Middle Aged; Mitochondria; Organophosphonates; Polyomavirus Infections | 2010 |
Determination of cidofovir in human plasma after low dose drug administration using high-performance liquid chromatography-tandem mass spectrometry.
Topics: Antiviral Agents; Calibration; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Drug Stability; Humans; Limit of Detection; Organophosphonates; Tandem Mass Spectrometry | 2010 |
Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Anti-Infective Agents, Local; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Ophthalmic Solutions; Organophosphonates; Pharmaceutical Preparations; Povidone-Iodine; Rabbits; Tobramycin; Treatment Outcome; Viral Plaque Assay | 2011 |
Cidofovir does not prevent caprine herpesvirus type-1 neural latency in goats.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Female; Ganglia; Goats; Herpesviridae Infections; Humans; Organophosphonates; Sacrococcygeal Region; Varicellovirus; Virus Latency; Virus Shedding | 2010 |
Renal failure five years after lung transplantation due to polyomavirus BK-associated nephropathy.
Topics: Adult; Aged; Cidofovir; Cytosine; Female; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Transplantation; Male; Middle Aged; Mycophenolic Acid; Organophosphonates; Polyomavirus Infections; Prednisone; Renal Insufficiency; Tacrolimus; TOR Serine-Threonine Kinases | 2010 |
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir.
Topics: Adenoviridae Infections; Cidofovir; Cytosine; Dermatitis, Exfoliative; Drug Eruptions; Eosinophilia; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Organophosphonates; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Syndrome; Treatment Outcome | 2011 |
Effects of cidofovir on human papillomavirus-positive cervical cancer cells xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cidofovir; Cytosine; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Organophosphonates; Papillomaviridae; Proliferating Cell Nuclear Antigen; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2010 |
Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient.
Topics: Adenovirus Infections, Human; Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Nephritis; Organophosphonates; Time Factors | 2011 |
Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytarabine; Cytokines; Cytosine; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Randomized Controlled Trials as Topic; T-Lymphocytopenia, Idiopathic CD4-Positive; Treatment Outcome | 2010 |
Treatment of recurrent respiratory papillomatosis lung involvement by cidofovir infusion.
Topics: Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Infusions, Intravenous; Lung; Middle Aged; Organophosphonates; Papillomavirus Infections; Pneumonia; Respiratory Function Tests; Respiratory Tract Infections; Tomography, X-Ray Computed; Treatment Outcome | 2011 |
Postexposure prevention of progressive vaccinia in SCID mice treated with vaccinia immune globulin.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Therapy, Combination; HeLa Cells; Humans; Immunoglobulins; Mice; Mice, SCID; Organophosphonates; Post-Exposure Prophylaxis; Skin; Survival Rate; Vaccination; Vaccinia; Vaccinia virus; Vero Cells | 2011 |
[Drug-drug interactions and nephrotoxicity].
Topics: Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Antirheumatic Agents; Cidofovir; Cisplatin; Contrast Media; Creatinine; Cytosine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney; Organophosphonates; Probenecid; Risk Factors; Uricosuric Agents | 2011 |
Treatment of adenovirus hepatitis with cidofovir in a pediatric liver transplant recipient.
Topics: Adenoviridae; Antiviral Agents; Biopsy; Cidofovir; Cytosine; DNA; Hepatitis; Humans; Infant; Kidney; Liver Transplantation; Male; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; Risk Factors; Treatment Outcome | 2012 |
Cidofovir may be deleterious in BK virus-associated nephropathy.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Kidney Diseases; Kidney Transplantation; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Tumor Virus Infections | 2011 |
Topical cidofovir for viral warts in children.
Topics: Administration, Topical; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Organophosphonates; Warts | 2011 |
Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.
Topics: Antiviral Agents; Base Sequence; Cidofovir; Cytosine; DNA; DNA Replication; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Organophosphonates; Poxviridae; Solutions | 2011 |
Novel method of intralesional cidofovir injection into laryngotracheal papillomata.
Topics: Antiviral Agents; Bronchoscopy; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Laryngeal Neoplasms; Neoplasm Recurrence, Local; Organophosphonates; Papilloma; Young Adult | 2011 |
Efficacy of intravenous cidofovir in the treatment of giant molluscum contagiosum in a patient with human immunodeficiency virus.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cidofovir; Cytosine; HIV Infections; Humans; Infusions, Intravenous; Male; Molluscum Contagiosum; Organophosphonates; Treatment Outcome | 2011 |
Activities of different classes of acyclic nucleoside phosphonates against BK virus in primary human renal cells.
Topics: BK Virus; Cell Line; Cell Proliferation; Cidofovir; Cytarabine; Cytosine; Humans; Isoxazoles; Kidney; Leflunomide; Nucleosides; Organophosphonates; Polymerase Chain Reaction; Vidarabine | 2011 |
Intraocular pharmacokinetics of a crystalline lipid prodrug, octadecyloxyethyl-cyclic-cidofovir, for cytomegalovirus retinitis.
Topics: Animals; Antiviral Agents; Autoradiography; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Eye; Intravitreal Injections; Organophosphonates; Prodrugs; Rabbits | 2011 |
Substantial effect of topical cidofovir 1% on recalcitrant warts in a renal-transplanted adolescent: a case report.
Topics: Administration, Cutaneous; Adolescent; Antiviral Agents; Cidofovir; Cytosine; Humans; Kidney Transplantation; Male; Organophosphonates; Skin Diseases; Warts | 2011 |
Intensive polyoma virus nephropathy treatment as a preferable approach for graft surveillance.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Graft Rejection; Graft Survival; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Tacrolimus | 2011 |
Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cowpox virus; Cytosine; Ectromelia virus; Esters; Guinea Pigs; Haplorhini; Humans; Liver; Organophosphonates; Rats; Vaccinia virus | 2011 |
Inhaled cidofovir as an adjuvant therapy for recurrent respiratory papillomatosis.
Topics: Administration, Inhalation; Aerosols; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Humans; Infant; Injections, Intralesional; Male; Off-Label Use; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections | 2011 |
Drug reaction with eosinophilia and systemic symptoms (DRESS) induced by cidofovir in a transplant recipient: a misunderstanding of DRESS.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Eruptions; Eosinophilia; Humans; Infant; Organ Transplantation; Organophosphonates; Syndrome | 2011 |
Effectiveness of cidofovir intralesional treatment in recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Cidofovir; Cohort Studies; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laser Therapy; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Retrospective Studies; Risk Assessment; Treatment Outcome; Young Adult | 2011 |
Novel polymeric/lipidic hybrid systems (PLHs) for effective Cidofovir delivery: preparation, characterization and comparative in vitro study with polymeric particles and liposomes.
Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; Desiccation; Diffusion; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Excipients; Herpesvirus 8, Human; Humans; Lipids; Liposomes; Organophosphonates; Particle Size; Polyesters; Polymers | 2011 |
New prodrugs of Adefovir and Cidofovir.
Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus | 2011 |
Topical treatment of cutaneous vaccinia virus infections in immunosuppressed hairless mice with selected antiviral substances.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cyclophosphamide; Cytosine; Female; Immune Tolerance; Immunosuppression Therapy; Mice; Mice, Hairless; Microbial Sensitivity Tests; Organophosphonates; Purines; Skin Diseases, Viral; Vaccinia; Vaccinia virus | 2011 |
Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis.
Topics: Acyclovir; Antiviral Agents; Chickenpox; Child; Child, Preschool; Cidofovir; Cytosine; Female; Herpes Zoster; Herpesvirus 3, Human; Hospitalization; Humans; Immunocompromised Host; Incidence; Infant; Male; Organophosphonates; Practice Guidelines as Topic | 2011 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine | 2011 |
An outbreak of adenovirus type 7 in a residential facility for severely disabled children.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; Disabled Children; Disease Outbreaks; Female; Hospitalization; Humans; Infant; Israel; Male; Molecular Typing; Organophosphonates; Residential Facilities; Respiratory Tract Infections; Retrospective Studies | 2011 |
Study of camelpox virus pathogenesis in athymic nude mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Mice; Mice, Nude; Organophosphonates; Orthopoxvirus; Poxviridae Infections | 2011 |
New human papillomavirus (HPV) types involved in epidermodysplasia verruciformis (EV) in 3 HIV-infected patients: response to topical cidofovir.
Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epidermodysplasia Verruciformis; Follow-Up Studies; Humans; Male; Middle Aged; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Sampling Studies; Severity of Illness Index; Treatment Outcome | 2011 |
Recalcitrant herpetic scrotal ulcer as a manifestation of immune reconstitution inflammatory syndrome.
Topics: Administration, Topical; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Biopsy, Needle; Cidofovir; Cytosine; Diagnosis, Differential; Follow-Up Studies; Herpes Simplex; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Immunohistochemistry; Male; Organophosphonates; Scrotum; Severity of Illness Index; Skin Ulcer; Treatment Outcome; Wound Healing | 2011 |
Intravenous cidofovir for resistant cutaneous warts in a patient with psoriasis treated with monoclonal antibodies.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiviral Agents; Cidofovir; Cytosine; Humans; Immunocompromised Host; Infusions, Intravenous; Male; Organophosphonates; Psoriasis; Treatment Outcome; Tumor Necrosis Factor-alpha; Warts | 2011 |
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus | 2011 |
Longitudinal analysis of human herpesvirus-8 DNA and antibodies in an Italian allogeneic stem cell transplant recipient.
Topics: Antibodies, Viral; Cidofovir; Cytosine; DNA, Viral; Encephalitis; Fatal Outcome; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Italy; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Organophosphonates; Stem Cell Transplantation; Transplantation, Homologous | 2011 |
Does human bocavirus infection depend on helper viruses? A challenging case report.
Topics: Antiviral Agents; Cidofovir; Coinfection; Cytosine; Diarrhea; DNA, Viral; Helper Viruses; Herpesvirus 6, Human; Human bocavirus; Humans; Infant; Male; Organophosphonates; Parvoviridae Infections; Polymerase Chain Reaction; Roseolovirus Infections; Viral Load | 2011 |
Virological failure of intralesional cidofovir therapy in recurrent respiratory papillomatosis is not associated with genetic or epigenetic changes of HPV11: complete genome comparison of sequential isolates.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Genome, Viral; Human papillomavirus 11; Humans; Molecular Sequence Data; Mutation; Organophosphonates; Papillomavirus Infections; Polymorphism, Single-Stranded Conformational; Respiratory Tract Infections; Sequence Analysis, DNA; Treatment Failure | 2011 |
Comparison of the quantitative performances and measurement uncertainty estimates obtained during method validation versus routine applications of a novel hydrophilic interaction chromatography method for the determination of cidofovir in human plasma.
Topics: Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphonates; Reference Standards; Uncertainty | 2012 |
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.
Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2012 |
Drug-induced uveitis in aids patients: two case reports.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Humans; Organophosphonates; Rifabutin; Uveitis | 2011 |
Treatment of recurrent respiratory papillomatosis and adverse reactions following off-label use of cidofovir (Vistide®).
Topics: Adverse Drug Reaction Reporting Systems; Antiviral Agents; Cidofovir; Cytosine; Injections, Intralesional; Neoplasms; Neutropenia; Off-Label Use; Organophosphonates; Papilloma; Papillomavirus Infections; Recurrence; Renal Insufficiency; Respiratory Tract Infections | 2012 |
Therapy and long-term prophylaxis of vaccinia virus respiratory infections in mice with an adenovirus-vectored interferon alpha (mDEF201).
Topics: Adenoviridae; Administration, Intranasal; Animals; Body Weight; Cidofovir; Cytosine; Female; Genetic Vectors; Interferon-alpha; Mice; Mice, Inbred BALB C; Organophosphonates; Protective Agents; Respiratory Tract Infections; Survival Analysis; Time Factors; Vaccinia; Vaccinia virus | 2011 |
Acute primary canine herpesvirus-1 dendritic ulcerative keratitis in an adult dog.
Topics: Animals; Antiviral Agents; Cidofovir; Corneal Ulcer; Cytosine; Dog Diseases; Dogs; Herpesviridae Infections; Herpesvirus 1, Canid; Immunocompromised Host; Male; Organophosphonates | 2012 |
Successful treatment with plasma exchange for disseminated cidofovir-resistant adenovirus disease in a pediatric SCT recipient.
Topics: Adenovirus Infections, Human; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Viral; Humans; Male; Organophosphonates; Plasma Exchange; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Stem Cell Transplantation; Transplantation, Homologous; Unrelated Donors | 2012 |
Structure of cyclic nucleoside phosphonate ester prodrugs: an inquiry.
Topics: Acetonitriles; Chloroform; Cidofovir; Crystallography, X-Ray; Cytosine; Esters; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism | 2012 |
A child with BK virus infection: inadequacy of current therapeutic strategies.
Topics: BK Virus; Brain Diseases; Cardiomyopathies; Child; Cidofovir; Cytosine; Encephalomyelitis; Fatal Outcome; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Organophosphonates; Polymerase Chain Reaction; Polyomavirus Infections; Viral Load | 2012 |
Adjuvant therapy for laryngeal papillomatosis.
Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antiviral Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Indoles; Infant; Laryngeal Diseases; Male; Middle Aged; Organophosphonates; Papilloma; Papillomavirus Vaccines; Vaccination; Valacyclovir; Valine | 2011 |
Evaluation of inhaled cidofovir as postexposure prophylactic in an aerosol rabbitpox model.
Topics: Administration, Inhalation; Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Lung; Male; Organophosphonates; Post-Exposure Prophylaxis; Rabbits; Vaccinia; Vaccinia virus | 2012 |
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins | 2011 |
Chronic acyclovir-resistant HSV-2 ulcer in an immunosuppressed patient treated with topical cidofovir.
Topics: Acyclovir; Administration, Cutaneous; Aged; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fissure in Ano; Herpesvirus 2, Human; Humans; Immunocompromised Host; Lymphoma, Mantle-Cell; Male; Organophosphonates; Stem Cell Transplantation | 2011 |
Cost-effectiveness of cidofovir treatment of polyomavirus nephropathy in kidney transplant recipients.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cost-Benefit Analysis; Cytosine; Decision Support Techniques; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Markov Chains; Middle Aged; Models, Economic; Models, Statistical; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2012 |
Anogenital pseudotumoral herpes and HIV infection: a new challenge for diagnosis and treatment.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Carcinoma, Squamous Cell; Cidofovir; Condylomata Acuminata; Cytosine; Diagnosis, Differential; Female; Foscarnet; Humans; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Thalidomide; Treatment Outcome; Tumor Virus Infections | 2012 |
Antiviral effect of HPMPC (Cidofovir®), entrapped in cationic liposomes: in vitro study on MDBK cell and BHV-1 virus.
Topics: Animals; Antiviral Agents; Cations; Cattle; Cell Culture Techniques; Cell Line; Cell Survival; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Drug Carriers; Herpesvirus 1, Bovine; Kidney; Lipids; Liposomes; Microscopy, Fluorescence; Organophosphonates; Real-Time Polymerase Chain Reaction; Virus Replication | 2012 |
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Viral; Eye; Female; Foscarnet; Ganciclovir; Humans; Organophosphonates; Plasma; Sequence Analysis, DNA | 2012 |
Viral-associated trichodysplasia: characterization of a novel polyomavirus infection with therapeutic insights.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Female; Hair Diseases; Hair Follicle; Humans; Middle Aged; Organophosphonates; Polyomavirus; Polyomavirus Infections | 2012 |
Longterm remission of more than 5 years in a patient with progressive multifocal leucoencephalopathy and sarcoidosis.
Topics: Anti-Inflammatory Agents; Antiviral Agents; Brain; Cidofovir; Cytosine; Female; Gait Disorders, Neurologic; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Methotrexate; Mianserin; Middle Aged; Mirtazapine; Organophosphonates; Prednisolone; Receptor, Serotonin, 5-HT2A; Sarcoidosis; Serotonin Antagonists | 2012 |
Adenovirus-induced interstitial nephritis following umbilical cord blood transplant for chronic lymphocytic leukemia.
Topics: Acute Kidney Injury; Adenoviridae Infections; Adult; Antineoplastic Combined Chemotherapy Protocols; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Fetal Blood; Follow-Up Studies; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Nephritis, Interstitial; Organophosphonates; Risk Assessment; Severity of Illness Index; Treatment Outcome; Unrelated Donors; Viremia | 2012 |
In vitro characterization of a nineteenth-century therapy for smallpox.
Topics: Animals; Canada; Cell Line; Cidofovir; Cytosine; Fluorescent Antibody Technique; HeLa Cells; History, 19th Century; Humans; In Vitro Techniques; Organophosphonates; Phytotherapy; Plant Extracts; Rabbits; Real-Time Polymerase Chain Reaction; Sarraceniaceae; Smallpox; United States; Variola virus; Virus Replication | 2012 |
Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Pancreas Transplantation; Recurrence; Stomach; Treatment Outcome | 2012 |
Transporter-targeted lipid prodrugs of cyclic cidofovir: a potential approach for the treatment of cytomegalovirus retinitis.
Topics: Animals; Antiviral Agents; Biological Transport; Biotinylation; Biotransformation; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Dogs; Eye; Lipid Metabolism; Lipids; Male; Octanols; Organophosphonates; Prodrugs; Rabbits; Solubility; Symporters; Technology, Pharmaceutical; Water | 2012 |
Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Humans; Microbial Sensitivity Tests; Molecular Structure; Mutant Proteins; Mutation, Missense; Organophosphonates; Orthopoxvirus; Recombinant Proteins; Selection, Genetic; Vaccinia virus; Viral Plaque Assay | 2012 |
Laryngeal papilloma.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Injections, Intralesional; Laryngeal Diseases; Laryngoscopy; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Reoperation; Respiratory Tract Infections | 2012 |
Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient.
Topics: Acyclovir; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Gels; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Real-Time Polymerase Chain Reaction; Transplantation, Homologous; Treatment Outcome | 2013 |
Progressive multifocal leucoencephalopathy after autologous bone marrow transplantation: a treatment option.
Topics: Antidepressive Agents, Tricyclic; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Mianserin; Middle Aged; Mirtazapine; Multiple Myeloma; Organophosphonates; Postoperative Complications; Transplantation, Autologous | 2011 |
A single cidofovir treatment rescues animals at progressive stages of lethal orthopoxvirus disease.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ectromelia virus; Ectromelia, Infectious; Female; Immunoglobulin G; Interferon-gamma; Mice; Mice, Inbred BALB C; Organophosphonates; Survival Analysis | 2012 |
The impact of cidofovir treatment on viral loads in adult recurrent respiratory papillomatosis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Female; Human papillomavirus 11; Human papillomavirus 6; Humans; Laryngeal Neoplasms; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Real-Time Polymerase Chain Reaction; Respiratory Tract Infections; Retrospective Studies; Viral Load | 2012 |
Failure of intravenous cidofovir for generalized verrucosis in a patient with severe combined immunodeficiency.
Topics: Antiviral Agents; Cidofovir; Cytosine; Epidermodysplasia Verruciformis; Follow-Up Studies; Humans; Male; Organophosphonates; Severe Combined Immunodeficiency; Treatment Failure; Young Adult | 2012 |
Successful response to cidofovir of adenovirus hepatitis during chemotherapy in a child with hepatoblastoma.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Female; Hepatitis, Viral, Human; Hepatoblastoma; Humans; Infant; Liver Neoplasms; Organophosphonates | 2012 |
BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: treatment response and evidence for nosocomial transmission.
Topics: Administration, Intravenous; Administration, Intravesical; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Child; Child, Preschool; Cidofovir; Cross Infection; Cystitis; Cytosine; Female; Hemorrhage; Humans; Male; Organophosphonates; Plasma; Polyomavirus Infections; Transplantation; Treatment Outcome; Urine; Viral Load | 2013 |
Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antiviral Agents; Area Under Curve; BK Virus; Cidofovir; Cross-Over Studies; Cytosine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Half-Life; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections; Viremia | 2013 |
[Usefulness of topical cidofovir treatment for recalcitrant molluscum contagiosum in immunocompromised children].
Topics: Administration, Topical; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cryosurgery; Cytosine; Female; Follow-Up Studies; Humans; Male; Molluscum Contagiosum; Opportunistic Infections; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
Experience of 11 years use of cidofovir in recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Infant; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Recurrence; Remission Induction; Respiratory Tract Infections; Young Adult | 2013 |
Current use of intralesional cidofovir for recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Chemotherapy, Adjuvant; Cidofovir; Cross-Sectional Studies; Cytosine; Humans; Injections, Intralesional; Organophosphonates; Papillomavirus Infections; Practice Patterns, Physicians'; Reoperation; Respiratory Tract Infections | 2013 |
Intralesional cidofovir in severe juvenile respiratory papillomatosis.
Topics: Antineoplastic Agents; Child; Child, Preschool; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Laryngeal Neoplasms; Male; Neoplasm Staging; Organophosphonates; Papilloma; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2012 |
An adenoviral vector-based expression and delivery system for the inhibition of wild-type adenovirus replication by artificial microRNAs.
Topics: Adenoviridae; Antiviral Agents; Biological Products; Cell Line; Cidofovir; Cytosine; Drug Synergism; Humans; MicroRNAs; Organophosphonates; RNA Interference; Viral Load; Viral Proteins; Virus Replication | 2013 |
Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice.
Topics: Animals; Antineoplastic Agents; Brain; Cachexia; Carcinoma; Cell Line, Tumor; Cidofovir; Cytokines; Cytosine; Female; Human papillomavirus 16; Humans; Kynurenine; Leukocyte Count; Liver; Mice; Mice, Nude; Organophosphonates; Papillomavirus Infections; Spleen; Splenomegaly; Tryptophan; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2013 |
Minimizing surgical management through the use of adjuvant medical therapies.
Topics: Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Humans; Laryngeal Neoplasms; Organophosphonates; Papilloma | 2012 |
Evolution of an amino acid based prodrug approach: stay tuned.
Topics: Amino Acids; Antiviral Agents; Cidofovir; Cytosine; Molecular Structure; Organophosphonates; Prodrugs | 2013 |
Treatment of anal intraepithelial neoplasia: has it come of age?
Topics: Antiviral Agents; Anus Neoplasms; Carcinoma in Situ; Cidofovir; Cytosine; Female; HIV Infections; Humans; Male; Ointments; Organophosphonates; Papillomavirus Infections | 2013 |
Safety of intralesional cidofovir in patients with recurrent respiratory papillomatosis: an international retrospective study on 635 RRP patients.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Female; Head and Neck Neoplasms; Humans; Injections, Intralesional; Male; Neutropenia; Off-Label Use; Organophosphonates; Papillomavirus Infections; Renal Insufficiency; Respiratory Tract Infections; Retrospective Studies; Treatment Outcome | 2013 |
Single-operator flexible nasolaryngoscopy-guided transthyrohyoid vocal fold injections.
Topics: Antineoplastic Agents; Cidofovir; Cytosine; Equipment Design; Female; Follow-Up Studies; Glucocorticoids; Humans; Injections; Laryngeal Diseases; Laryngoscopes; Laryngoscopy; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome; Vocal Cords | 2013 |
Screening for BK viremia reduces but does not eliminate the risk of BK nephropathy: a single-center retrospective analysis.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cytosine; Early Diagnosis; Female; Glomerular Filtration Rate; Graft Survival; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Mass Screening; Middle Aged; Multivariate Analysis; Organophosphonates; Polyomavirus Infections; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Texas; Time Factors; Tumor Virus Infections; Viral Load; Viremia; Young Adult | 2013 |
Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient.
Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Encephalomyelitis; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic, T-Cell; Middle Aged; Organophosphonates | 2013 |
Evaluation of intratympanic formulations for inner ear delivery: methodology and sustained release formulation testing.
Topics: Chemistry, Pharmaceutical; Cidofovir; Computer Simulation; Cytosine; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Ear, Inner; Ear, Middle; Membranes, Artificial; Models, Biological; Organophosphonates; Polyethylene Glycols; Polyglactin 910 | 2014 |
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA | 2013 |
The combination of the antiviral agent cidofovir and anti-EGFR antibody cetuximab exerts an antiproliferative effect on HPV-positive cervical cancer cell lines' in-vitro and in-vivo xenografts.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antiviral Agents; Cell Cycle; Cell Line, Tumor; Cetuximab; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Organophosphonates; Papillomaviridae; Uterine Cervical Neoplasms | 2013 |
Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage.
Topics: Antiviral Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line; Cidofovir; Computational Biology; Cytosine; DNA Damage; DNA Repair; Down-Regulation; Gene Expression Profiling; Gene Regulatory Networks; HeLa Cells; Humans; Oligonucleotide Array Sequence Analysis; Organophosphonates; Papillomaviridae; Retinoid X Receptors; rho GTP-Binding Proteins; Signal Transduction; Up-Regulation | 2013 |
Intravitreal cidofovir injection for the management of chronic glaucoma in dogs.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dog Diseases; Dogs; Female; Glaucoma; Intraocular Pressure; Male; Organophosphonates; Retrospective Studies | 2014 |
Clinicopathological findings in persistent corneal cowpox infection.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Corneal Ulcer; Cowpox; Cowpox virus; Cytosine; DNA, Viral; Eye Infections, Viral; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Keratoplasty, Penetrating; Middle Aged; Mycophenolic Acid; Organophosphonates; Real-Time Polymerase Chain Reaction; Reoperation; Virus Activation; Visual Acuity | 2013 |
Human papillomavirus: the fundamentals of HPV for oral health care providers.
Topics: Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Mouth Neoplasms; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Papillomavirus Vaccines | 2013 |
Successful treatment of perianal giant condyloma acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.
Topics: Administration, Topical; Antineoplastic Agents; Antiviral Agents; Anus Neoplasms; Buschke-Lowenstein Tumor; Cidofovir; Combined Modality Therapy; Cytosine; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunocompromised Host; Interleukin-2; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Treatment Outcome | 2013 |
Intralesional cidofovir for treating extensive genital verrucous herpes simplex virus infection.
Topics: Antiviral Agents; Cidofovir; Coinfection; Cytosine; Hepatitis C; Herpes Genitalis; HIV Infections; Humans; Injections, Intralesional; Male; Middle Aged; Organophosphonates | 2013 |
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists.
Topics: Anticarcinogenic Agents; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Health Care Surveys; Human papillomavirus 11; Human papillomavirus 6; Humans; Injections, Intralesional; Laryngeal Neoplasms; Laser Therapy; Neoplasm Recurrence, Local; Organophosphonates; Papillomavirus Infections; Pediatrics; Practice Patterns, Physicians'; Respiratory Tract Infections; Treatment Outcome; United Kingdom | 2013 |
[BK virus infections in pediatric kidney transplant recipients].
Topics: Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; DNA, Viral; Female; Graft Rejection; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections; Turkey | 2013 |
Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells.
Topics: Animals; Antiviral Agents; Apoptosis; Blotting, Western; Cells, Cultured; Cidofovir; Cyclic AMP; Cytosine; Gammaherpesvirinae; Herpesviridae Infections; Humans; Kidney; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Organophosphonates; Organophosphorus Compounds; Prodrugs; Tumor Virus Infections; Virus Activation; Virus Replication | 2013 |
Treatment of BK virus-associated hemorrhagic cystitis in pediatric hematopoietic stem cell transplant recipients with cidofovir: a single-center experience.
Topics: Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Tumor Virus Infections; Viral Load | 2013 |
Generation and characterization of a GCV resistant HCMV UL97-mutation and a drug sensitive UL54-mutation.
Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutagenesis; Mutation, Missense; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins | 2013 |
Clinical efficiency of quadrivalent HPV (types 6/11/16/18) vaccine in patients with recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Follow-Up Studies; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Injections, Intralesional; Injections, Intramuscular; Laryngoscopy; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Papillomavirus Vaccines; Pilot Projects; Prospective Studies; Respiratory Tract Infections; Romania; Young Adult | 2014 |
Degrees of dysplasia based on viral typing in patients with cidofovir use and recurrent respiratory papillomatosis.
Topics: Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Precancerous Conditions; Recurrence; Respiratory Tract Infections; Respiratory Tract Neoplasms; Retrospective Studies | 2013 |
Safety of cidofovir by intratympanic delivery technique.
Topics: Animals; Antiviral Agents; Cidofovir; Cochlea; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hearing Loss, Sensorineural; Injections; Organophosphonates | 2014 |
Cidofovir: a novel antitumor agent for glioblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cidofovir; Cytosine; DNA Breaks, Double-Stranded; DNA Replication; Female; Glioblastoma; Humans; Mice; Mice, Nude; Organophosphonates; Spheroids, Cellular; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Effect of vocal fold injection of cidofovir and bevacizumab in a porcine model.
Topics: Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Biopsy, Needle; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Immunohistochemistry; Injections, Intralesional; Models, Animal; Organophosphonates; Random Allocation; Sensitivity and Specificity; Sus scrofa; Swine; Vocal Cords | 2014 |
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cidofovir; Cytosine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Resistance, Viral; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Mice; Mice, Nude; Organophosphonates; Phenotype; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2013 |
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates | 2014 |
Single-dose pharmacokinetics of cidofovir in continuous venovenous hemofiltration.
Topics: Antiviral Agents; Cidofovir; Critical Illness; Cytosine; Hemofiltration; Humans; Male; Middle Aged; Organophosphonates; Probenecid | 2014 |
[Cidofovir dosage in a critically ill patient undergoing continuous veno-venous hemodiafiltration].
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Critical Illness; Cytosine; Female; Hemofiltration; Humans; Organophosphonates; Young Adult | 2014 |
High burden of BK virus-associated hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Aged; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Female; Graft vs Host Disease; Health Care Costs; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hospital Costs; Humans; Incidence; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Risk Factors; Transplantation, Homologous; Tumor Virus Infections; Viremia; Young Adult | 2014 |
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Follow-Up Studies; Foscarnet; Herpes Simplex; HIV Infections; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Retrospective Studies; Skin Diseases, Viral; Skin Ulcer; Socioeconomic Factors; Thymidine Kinase; Treatment Outcome | 2014 |
UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Organophosphonates; Viral Proteins | 2014 |
Urrets-Zavalia syndrome as a complication of ocular hypotonia due to intravenous cidofovir treatment.
Topics: Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Infusions, Intravenous; Laryngeal Neoplasms; Ocular Hypotension; Organophosphonates; Papilloma; Pupil Disorders; Tracheal Neoplasms | 2014 |
Successful treatment of refractory cutaneous warts using topical 3% cidofovir in a child after heart transplant.
Topics: Administration, Topical; Antiviral Agents; Child; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Opportunistic Infections; Organophosphonates; Postoperative Period; Treatment Outcome; Warts | 2014 |
N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity.
Topics: Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Herpesviridae; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Prodrugs; Structure-Activity Relationship; Virus Replication | 2014 |
Use of cidofovir in HPV patients with recurrent respiratory papillomatosis.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Injections, Intralesional; Male; Middle Aged; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Respiratory Tract Infections; Retrospective Studies; Young Adult | 2014 |
A plasma concentration of α-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1.
Topics: Adult; Animals; Biological Transport; Cell Line; CHO Cells; Cidofovir; Cricetulus; Cytosine; Humans; Ketoglutaric Acids; Kinetics; Ligands; Middle Aged; Organic Anion Transporters; Organophosphonates; p-Aminohippuric Acid; Swine | 2014 |
Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; High-Throughput Nucleotide Sequencing; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Organophosphonates; Pneumonia, Viral; Time Factors; Viral Proteins; Virus Replication | 2014 |
Formulation of cidofovir improves the anti-papillomaviral activity of topical treatments in the CRPV/rabbit model.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Chemistry, Pharmaceutical; Cidofovir; Cottontail rabbit papillomavirus; Cytosine; Excipients; Organophosphonates; Papillomavirus Infections; Rabbits; Treatment Outcome; Tumor Virus Infections | 2014 |
In vitro efficacy of brincidofovir against variola virus.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Organophosphonates; Smallpox; Variola virus | 2014 |
Adenovirus causing fever, upper respiratory infection, and allograft nephritis complicated by persistent asymptomatic viremia.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Kidney Transplantation; Nephritis, Interstitial; Organophosphonates; Respiratory Tract Infections; Viremia; Young Adult | 2014 |
Polyomavirus BK--a potential new therapeutic target for painful bladder syndrome/interstitial cystitis?
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cidofovir; Cystitis, Interstitial; Cystoscopy; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Polyomavirus; Polyomavirus Infections; Prognosis; Quinolones; Real-Time Polymerase Chain Reaction; Treatment Outcome; Urinary Bladder, Overactive | 2014 |
Cidofovir in pediatric solid organ transplant recipients: University of Nebraska experience.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cohort Studies; Creatinine; Cytosine; Female; Glomerular Filtration Rate; Hematuria; Hospitals, University; Humans; Infant; Kidney; Male; Nebraska; Organophosphonates; Proteinuria; Retrospective Studies; Transplants | 2015 |
Successful Treatment of Disseminated Adenovirus Infection in an Infant With Acute Lymphoblastic Leukemia.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Humans; Immunocompromised Host; Infant; Male; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Survival Rate | 2015 |
Cidofovir gel as treatment of follicular spicules in multiple myeloma.
Topics: Aged; Antiviral Agents; Carcinoma, Merkel Cell; Cidofovir; Cytosine; Gels; Hair Follicle; Humans; Male; Merkel cell polyomavirus; Multiple Myeloma; Organophosphonates; Polyomavirus Infections; Skin Neoplasms | 2015 |
[Efficacy and safety of intravenous cidofovir in the treatment of giant molluscum contagiosum in an immunosuppressed patient].
Topics: Antiviral Agents; Cidofovir; Cytosine; Follow-Up Studies; Genital Diseases, Male; Humans; Infusions, Intravenous; Male; Molluscum Contagiosum; Opportunistic Infections; Organophosphonates; Young Adult | 2014 |
Surgery or topical therapy for vulval intraepithelial neoplasia.
Topics: Aminoquinolines; Carcinoma in Situ; Cidofovir; Cytosine; Female; Humans; Imiquimod; Organophosphonates; Vulvar Neoplasms | 2014 |
Orf Infection in a Patient with Stat1 Gain-of-Function.
Topics: Adult; Animals; Antiviral Agents; Base Sequence; Candidiasis, Chronic Mucocutaneous; Cidofovir; Cytosine; DNA Mutational Analysis; Ecthyma, Contagious; Humans; Immunologic Deficiency Syndromes; Interleukin-17; Male; Mutation, Missense; Organophosphonates; Sheep, Domestic; STAT1 Transcription Factor; Zoonoses | 2015 |
Enhanced efficacy of cidofovir combined with vaccinia immune globulin in treating progressive cutaneous vaccinia virus infections in immunosuppressed hairless mice.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Female; Immunoglobulins; Infusions, Parenteral; Mice, Hairless; Mice, SCID; Organophosphonates; Skin Diseases, Infectious; Treatment Outcome; Vaccinia | 2015 |
Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Cercopithecine; Macaca mulatta; Mice; Organophosphonates; Simplexvirus; Trifluridine; Vero Cells; Viral Plaque Assay | 2014 |
Accurate ab initio prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA; DNA-Binding Proteins; G-Quadruplexes; Lac Repressors; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Operator Regions, Genetic; Organophosphonates; Promoter Regions, Genetic; Protein Binding; Protons | 2014 |
Observations on the use of cidofovir for BK virus infection in renal transplantation.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Tumor Virus Infections; Viral Load; Viremia | 2014 |
Antiviral effect of cidofovir on parvovirus B19 replication.
Topics: Antiviral Agents; Blotting, Southern; Cell Line; Cell Proliferation; Cell Survival; Cidofovir; Cytosine; Erythroid Precursor Cells; Organophosphonates; Parvovirus B19, Human; Real-Time Polymerase Chain Reaction; Virus Replication | 2015 |
Intracellular concentrations determine the cytotoxicity of adefovir, cidofovir and tenofovir.
Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Organic Anion Transport Protein 1; Organophosphonates; Tenofovir; Toxicity Tests | 2015 |
Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Alanine Transaminase; Animals; Body Weight; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load | 2014 |
Trends in the management of recurrent respiratory papillomatosis in Japan.
Topics: Antiviral Agents; Cidofovir; Cytosine; Debridement; Disease Management; Humans; Japan; Laser Therapy; Lasers, Gas; Lasers, Solid-State; Medicine, Chinese Traditional; Organophosphonates; Otolaryngology; Papillomavirus Infections; Practice Patterns, Physicians'; Respiratory Tract Infections; Surveys and Questionnaires | 2015 |
Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox.
Topics: Acyclovir; Antiviral Agents; Catalytic Domain; Cidofovir; Cytosine; Drug Design; Humans; Kinetics; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Nucleoside-Phosphate Kinase; Organophosphonates; Small Molecule Libraries; Smallpox; Species Specificity; Structure-Activity Relationship; Thermodynamics; Variola virus; Viral Proteins | 2015 |
The effect of cidofovir on adenovirus plasma DNA levels in stem cell transplantation recipients without T cell reconstitution.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; DNA, Viral; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Infant; Killer Cells, Natural; Lymphocyte Count; Lymphocyte Depletion; Male; Organophosphonates; T-Lymphocytes; Transplantation, Homologous; Viral Load; Viremia | 2015 |
Topical cidofovir-induced acute kidney injury in two severely immunocompromised patients with refractory multidrug-resistant herpes simplex virus infections.
Topics: Acute Kidney Injury; Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Herpes Simplex; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates | 2016 |
Disseminated adenovirus disease in heart transplant recipient presenting with conjunctivitis.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Aged; Antiviral Agents; Cidofovir; Conjunctivitis; Cytosine; Heart Transplantation; Humans; Immunocompromised Host; Immunosuppression Therapy; Male; Organophosphonates; Pneumonia, Viral; Postoperative Complications; Transplant Recipients | 2015 |
The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors.
Topics: Animals; Antiviral Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cidofovir; Cytosine; Embryo, Nonmammalian; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Fibroblasts; Humans; Immunoenzyme Techniques; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, SCID; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zebrafish | 2015 |
The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease.
Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Injections, Intradermal; Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia; Vaccinia virus; Variola virus | 2015 |
Treatment of BK virus-associated hemorrhagic cystitis with low-dose intravenous cidofovir in patients undergoing allogeneic hematopoietic cell transplantation.
Topics: Administration, Intravenous; Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Time Factors; Transplantation, Homologous; Treatment Outcome; Tumor Virus Infections; Viral Load | 2015 |
Effect of Leflunomide, Cidofovir and Ciprofloxacin on replication of BKPyV in a salivary gland in vitro culture system.
Topics: Animals; Antigens, Viral, Tumor; Antiviral Agents; BK Virus; Cells, Cultured; Cidofovir; Ciprofloxacin; Cytosine; Humans; Isoxazoles; Leflunomide; Organophosphonates; RNA, Messenger; RNA, Viral; Salivary Glands; Time Factors; Viral Load; Virus Replication | 2015 |
Recalcitrant warts and topical cidofovir: predictive factors of good response.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Male; Middle Aged; Organophosphonates; Treatment Outcome; Warts; Young Adult | 2016 |
Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Cidofovir; Cytosine; Drug-Related Side Effects and Adverse Reactions; Humans; Immunocompromised Host; Medical Records; Organophosphonates; Pneumonia; Respiratory Insufficiency; Retrospective Studies; Treatment Outcome | 2015 |
Intravesical cidofovir to treat BK virus-associated hemorrhagic cystitis in children after hematopoietic stem cell transplantation.
Topics: Administration, Intravesical; Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cystitis; Cytosine; Female; Formaldehyde; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Immune System; Male; Organophosphonates; Polymerase Chain Reaction; Polyomavirus Infections; Time Factors | 2015 |
[Research of suppression of the herpes simplex virus reproduction with drug resistance by combination phosphite of acycloguanosine with some antiherpetic drugs].
Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Foscarnet; Glycyrrhizic Acid; Herpesvirus 1, Human; Humans; Interferon-alpha; Organophosphonates; Phosphites; Ribavirin; Vero Cells; Vidarabine; Virus Replication | 2014 |
Enhanced suppression of adenovirus replication by triple combination of anti-adenoviral siRNAs, soluble adenovirus receptor trap sCAR-Fc and cidofovir.
Topics: Adenoviridae; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Drug Synergism; HeLa Cells; Humans; Organophosphonates; Receptors, Virus; RNA, Small Interfering; Virus Internalization; Virus Replication | 2015 |
Intralesional cidofovir for the treatment of a plantar wart.
Topics: Antiviral Agents; Cidofovir; Cytosine; Foot Dermatoses; Humans; Injections, Intralesional; Organophosphonates; Warts | 2015 |
Identification of newly detected, drug-related HCMV UL97- and UL54-mutations using a modified plaque reduction assay.
Topics: Adult; Antiviral Agents; Cell Line; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Genotype; Humans; Infant; Male; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2015 |
Prolonged outbreak of adenovirus A31 in allogeneic stem cell transplant recipients.
Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Disease Outbreaks; DNA, Viral; Humans; Organophosphonates; Phylogeny; Retrospective Studies; Stem Cell Transplantation; Sweden; Time Factors | 2015 |
Preparation and characterization of bioadhesive controlled-release gels of cidofovir for vaginal delivery.
Topics: Adhesiveness; Adhesives; Administration, Intravaginal; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Stability; Gels; Herpesvirus 1, Bovine; Mucous Membrane; Organophosphonates; Rabbits; Vero Cells | 2015 |
New drug on the horizon for treating adenovirus.
Topics: Adenoviridae Infections; Adenoviruses, Human; Adoptive Transfer; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Immunocompromised Host; Organophosphonates; T-Lymphocytes | 2015 |
In Vitro and In Vivo Evaluation of Cidofovir as a Topical Ophthalmic Antiviral for Ocular Canine Herpesvirus-1 Infections in Dogs.
Topics: Administration, Ophthalmic; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Dog Diseases; Dogs; Herpesviridae Infections; Herpesvirus 1, Canid; Madin Darby Canine Kidney Cells; Microscopy, Confocal; Organophosphonates; Random Allocation; Vero Cells; Virus Shedding | 2015 |
Risk Factors for Dysplasia in Recurrent Respiratory Papillomatosis in an Adult and Pediatric Population.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma; Cell Transformation, Neoplastic; Child; Child, Preschool; Cidofovir; Cytosine; Humans; Infant; Middle Aged; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Respiratory Tract Neoplasms; Retrospective Studies; Risk Factors; Sex Factors; Smoking; Young Adult | 2016 |
The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Hemorrhagic Fever, Ebola; Human Umbilical Vein Endothelial Cells; Humans; Lipids; Male; Organophosphonates; Structure-Activity Relationship; Vero Cells; Virus Replication | 2016 |
The Oncogenic Small Tumor Antigen of Merkel Cell Polyomavirus Is an Iron-Sulfur Cluster Protein That Enhances Viral DNA Replication.
Topics: Antigens, Viral, Tumor; Antiviral Agents; Cell Line; Cell Nucleus; Cidofovir; Cytosine; DNA Mutational Analysis; DNA Replication; Electron Spin Resonance Spectroscopy; Humans; Iron-Sulfur Proteins; Merkel cell polyomavirus; Mutant Proteins; Organophosphonates; Protein Transport; Virus Replication | 2016 |
Is recurrent respiratory papillomatosis a manageable or curable disease?
Topics: Adolescent; Adult; Aged; Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Combined Modality Therapy; Cytosine; Female; Humans; Injections, Intralesional; Laryngoscopy; Larynx; Laser Therapy; Male; Microsurgery; Middle Aged; Organophosphonates; Papillomavirus Infections; Postoperative Complications; Recurrence; Remission Induction; Respiratory Tract Infections; Retrospective Studies; Treatment Outcome; Voice Disorders; Voice Quality; Young Adult | 2016 |
Glottic Cancer: A Metamorphosing Disease.
Topics: Adolescent; Adult; Antiviral Agents; Carcinoma, Squamous Cell; Cidofovir; Cytosine; Diagnostic Errors; Female; Glottis; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Laryngoscopy; Laser Therapy; Lasers, Solid-State; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Retrospective Studies; Smoking; Squamous Cell Carcinoma of Head and Neck | 2016 |
Pharmacokinetics and safety of intravesicular cidofovir in allogeneic HSCT recipients.
Topics: Adenoviridae Infections; Administration, Intravesical; Adolescent; Aged; Antiviral Agents; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Plasma; Prospective Studies; Transplantation, Homologous; Young Adult | 2016 |
Trichodysplasia Spinulosa in a 20-Month-Old Girl With a Good Response to Topical Cidofovir 1%.
Topics: Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Female; Hair Diseases; Hair Follicle; Humans; Immunocompromised Host; Infant; Organophosphonates; Polyomavirus | 2015 |
Cidofovir in the Treatment of BK Virus-Associated Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Drug Administration Schedule; Female; Glomerular Filtration Rate; Graft Survival; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Middle Aged; Myeloablative Agonists; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Tumor Virus Infections; Viral Load | 2016 |
A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.
Topics: 3T3 Cells; Adenine; Animals; Antiviral Agents; Cell Line; Cell Line, Transformed; Cell Survival; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Forecasting; Gene Expression Regulation; HEK293 Cells; Humans; Kidney Tubules, Proximal; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates | 2016 |
Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1.
Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Cidofovir; Cytidine Triphosphate; Cytosine; Drug Resistance, Neoplasm; Female; HeLa Cells; Humans; Microbial Sensitivity Tests; Nucleoside-Phosphate Kinase; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Phosphorylation; Solute Carrier Proteins; Uridine Triphosphate; Uterine Cervical Neoplasms | 2016 |
Intralesional cidofovir injection for recurrent respiratory papillomatosis in Japan.
Topics: Adult; Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Human papillomavirus 6; Humans; Injections, Intralesional; Japan; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Respiratory Tract Infections; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2016 |
Cidofovir for treatment of progressive multifocal leukoencephalopathy in a newly diagnosed sarcoidosis patient - a valid therapeutic option?
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Humans; Image Processing, Computer-Assisted; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates | 2016 |
A novel corneal explant model system to evaluate antiviral drugs against feline herpesvirus type 1 (FHV-1).
Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cidofovir; Cornea; Cytosine; Drug Evaluation, Preclinical; Organ Culture Techniques; Organophosphonates; Varicellovirus; Virus Cultivation | 2016 |
In kidney transplant recipients with BK polyomavirus infection, early BK nephropathy, microvascular inflammation, and serum creatinine are risk factors for graft loss.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Creatinine; Cytosine; Female; Graft Rejection; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Plasma Exchange; Polyomavirus Infections; Prognosis; Risk Factors; Tumor Virus Infections; Viremia | 2016 |
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins | 2016 |
Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance.
Topics: Adolescent; Adult; Antiviral Agents; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Infant; Middle Aged; Mutation; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Genetic; Viral Proteins | 2016 |
Combination therapies using an intratympanic polymer gel delivery system in the guinea pig animal model: A safety study.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Drug Combinations; Drug Delivery Systems; Follow-Up Studies; Ganciclovir; Glucocorticoids; Guinea Pigs; Hearing Loss; Hydrogels; Injection, Intratympanic; Organophosphonates; Polyesters; Polyethylene Glycols; Polymers | 2016 |
Enhanced inhibition of parvovirus B19 replication by cidofovir in extendedly exposed erythroid progenitor cells.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Erythroid Precursor Cells; Humans; Organophosphonates; Parvovirus B19, Human; Primary Cell Culture; Virus Replication | 2016 |
Complex management of resistant oral herpes simplex virus infection following hematopoietic stem cell transplantation: potential role of topical cidofovir.
Topics: Administration, Topical; Aged; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Organophosphonates; Transplantation Conditioning | 2016 |
Epstein-Barr virus-associated leukemic lymphoma after allogeneic stem cell transplantation.
Topics: Adolescent; Adult; Cidofovir; Cytosine; Epstein-Barr Virus Infections; Female; Hematopoietic Stem Cell Transplantation; Herpesvirus 4, Human; Humans; Leukemia, Lymphoid; Lymphocyte Transfusion; Lymphoproliferative Disorders; Male; Organophosphonates; Rituximab; Transplantation, Homologous; Treatment Outcome | 2016 |
Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms.
Topics: Antiviral Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cidofovir; Cytosine; DNA Damage; Female; Head and Neck Neoplasms; HeLa Cells; Humans; Male; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms | 2016 |
Monitoring of adenovirus (ADV)-specific T cells in a boy with ADV pneumonia and disseminated disease after lung transplantation.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Bronchoalveolar Lavage Fluid; Child, Preschool; Cidofovir; Cytosine; Enzyme-Linked Immunospot Assay; Feasibility Studies; Flow Cytometry; Humans; Immunocompromised Host; Immunosuppression Therapy; Lung Transplantation; Male; Monitoring, Physiologic; Organophosphonates; Pneumonia, Viral; Real-Time Polymerase Chain Reaction; T-Lymphocytes; Viral Load | 2016 |
Effect of high-dose vocal fold injection of cidofovir and bevacizumab in a porcine model.
Topics: Animals; Bevacizumab; Biopsy, Needle; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunohistochemistry; Injections, Intralesional; Laryngeal Neoplasms; Odds Ratio; Organophosphonates; Papilloma; Random Allocation; Sensitivity and Specificity; Sus scrofa; Vocal Cords | 2017 |
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load | 2016 |
Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir.
Topics: Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Foscarnet; Herpes Simplex; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Infusions, Intravenous; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retinal Necrosis Syndrome, Acute; Retrospective Studies; Simplexvirus; Vitreous Body | 2018 |
BK polyomavirus encephalitis in a patient with thrombotic microangiopathy after an allogeneic hematopoietic stem cell transplant.
Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Antiviral Agents; BK Virus; Cidofovir; Ciprofloxacin; Cystitis; Cytosine; Encephalitis; Fatal Outcome; Female; Hematopoietic Stem Cell Transplantation; Hematuria; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Immunologic Factors; Immunosuppressive Agents; Magnetic Resonance Imaging; Middle Aged; Organophosphonates; Polyomavirus Infections; Thrombotic Microangiopathies; Tomography, X-Ray Computed; Transplantation, Homologous; Tumor Virus Infections; Virus Activation | 2016 |
Topical Cidofovir for Recalcitrant Verrucae in Individuals with Severe Combined Immunodeficiency After Hematopoietic Stem Cell Transplantation.
Topics: Antiviral Agents; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Severe Combined Immunodeficiency; Treatment Outcome; Warts | 2017 |
[Intralesional cidofovir in human papilomavirus infection in interdigital spaces].
Topics: Antiviral Agents; Cidofovir; Cytosine; Fingers; Humans; Infusions, Intralesional; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Warts | 2017 |
Dodecyl Amino Glucoside Enhances Transdermal and Topical Drug Delivery via Reversible Interaction with Skin Barrier Lipids.
Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Cidofovir; Cytosine; Drug Delivery Systems; Epidermis; Glucosides; Hexoses; Humans; Hydrophobic and Hydrophilic Interactions; Keratinocytes; Lipids; Organophosphonates; Permeability; Skin; Skin Absorption; Structure-Activity Relationship; Theophylline | 2017 |
Reduced cell viability and apoptosis induction in human thyroid carcinoma and mesothelioma cells exposed to cidofovir.
Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cidofovir; Cytosine; DNA Fragmentation; Female; Humans; Mesothelioma; Organophosphonates; Papillomavirus Infections; Polyomavirus Infections; Thyroid Neoplasms; Tumor Virus Infections; Uterine Cervical Neoplasms | 2017 |
Comparison of cidofovir and the measles, mumps, and rubella vaccine in the treatment of recurrent respiratory papillomatosis.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Combined Modality Therapy; Cytosine; Debridement; Female; Humans; Infant; Male; Measles-Mumps-Rubella Vaccine; Organophosphonates; Papillomavirus Infections; Remission Induction; Respiratory Tract Infections; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2017 |
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles | 2017 |
Recurrent Herpes Labialis in Adults: New Tricks for an Old Dog.
Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Labialis; Herpesvirus 1, Human; Humans; Hyperthermia, Induced; Infusions, Parenteral; Organophosphonates; Recurrence; Stomatitis, Herpetic; Viral Load | 2017 |
Treatment of Previously Refractory Ocular Surface Squamous Neoplasia With Topical Cidofovir.
Topics: Administration, Ophthalmic; Aged; Carcinoma in Situ; Cidofovir; Conjunctival Neoplasms; Cytosine; Humans; Male; Neoplasm Recurrence, Local; Organophosphonates | 2017 |
New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1.
Topics: Acyclovir; Antiviral Agents; Benzimidazoles; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Nucleosides; Organophosphonates | 2017 |
Renal Toxicity in Pediatric Patients Receiving Cidofovir for the Treatment of Adenovirus Infection.
Topics: Acute Kidney Injury; Adenovirus Infections, Human; Adolescent; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Humans; Infant; Infant, Newborn; Organophosphonates; Retrospective Studies; Young Adult | 2017 |
Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration.
Topics: Adenocarcinoma; Administration, Intravaginal; Antiviral Agents; Cell Line, Tumor; Cervix Uteri; Cidofovir; Cyclodextrins; Cytosine; Drug Delivery Systems; Female; Humans; Nanoparticles; Organophosphonates; Paclitaxel; Printing; Solubility; Uterine Cervical Neoplasms | 2017 |
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Mutation; Organ Transplantation; Organophosphonates; Postoperative Complications; Real-Time Polymerase Chain Reaction; Retrospective Studies; Thailand; Young Adult | 2017 |
Successful Treatment of BK Virus Hemorrhagic Cystitis (HC) Post Allogenic Hematopoietic Stem Cell Transplantation with Low Dose Cidofovir.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Male; Organophosphonates; Polyomavirus Infections; Transplantation, Homologous; Tumor Virus Infections | 2017 |
Human Papillomavirus DNA Methylation Predicts Response to Treatment Using Cidofovir and Imiquimod in Vulval Intraepithelial Neoplasia 3.
Topics: Aminoquinolines; Biomarkers; Carcinoma in Situ; Cidofovir; Cytosine; DNA Methylation; DNA, Viral; Drug Therapy, Combination; Female; Genes, Viral; Humans; Imiquimod; Neoplasm Staging; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Promoter Regions, Genetic; ROC Curve; Treatment Outcome; Vulvar Neoplasms | 2017 |
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
Topics: A549 Cells; Adenoviridae Infections; Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Cidofovir; Cricetinae; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Immunosuppression Therapy; Liver; Male; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Induction, treatment and prevention of eczema vaccinatum in atopic dermatitis mouse models.
Topics: Animals; Antibodies, Viral; Antiviral Agents; CD4-Positive T-Lymphocytes; Cidofovir; Cytosine; Dermatitis, Atopic; Disease Models, Animal; Ectromelia virus; Female; Humans; Kaposi Varicelliform Eruption; Mice; Organophosphonates; Smallpox Vaccine | 2017 |
Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery.
Topics: Administration, Cutaneous; Alkenes; Cidofovir; Cytosine; Drug Liberation; Epidermis; Fibroblasts; Galactose; Galactosides; Humans; Hydrocortisone; Keratinocytes; Lipids; Organophosphonates; Permeability; Skin; Skin Absorption; Structure-Activity Relationship; Theophylline; Water | 2017 |
Overcoming the Hydrolytic Lability of a Reaction Intermediate in Production of Protein/Drug Conjugates: Conjugation of an Acyclic Nucleoside Phosphonate to a Model Carrier Protein.
Topics: Adenine; Chromatography, Ion Exchange; Chromatography, Liquid; Cidofovir; Cytosine; HIV; Nucleosides; Organophosphonates; Pharmaceutical Preparations; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tenofovir | 2017 |
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunoglobulins; Immunoglobulins, Intravenous; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Postoperative Complications; Tissue Donors | 2017 |
Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Disease Models, Animal; Humans; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Lymphohistiocytosis, Hemophagocytic; Mice; Mice, Inbred BALB C; Mice, Knockout; Muromegalovirus; Organophosphonates; T-Lymphocytes; Toll-Like Receptor 3; Toll-Like Receptor 9; Virus Diseases; Virus Replication | 2017 |
Intracellular trafficking and therapeutic outcome of multiwalled carbon nanotubes modified with cyclodextrins and polyethylenimine.
Topics: Animals; Antiviral Agents; beta-Cyclodextrins; Biological Transport; Chlorocebus aethiops; Cidofovir; Cytomegalovirus; Cytosine; Drug Carriers; Drug Liberation; Green Fluorescent Proteins; Kinetics; Lysosomes; Nanotubes, Carbon; Organophosphonates; Plasmids; Polyethyleneimine; Rhodamines; Vero Cells | 2018 |
Case 1-2018. A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure.
Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Lung; Nasopharynx; Opportunistic Infections; Organophosphonates; Radiography, Thoracic; Renal Insufficiency; Respiratory Insufficiency; Stem Cell Transplantation; Tomography, X-Ray Computed; Viral Load | 2018 |
Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient.
Topics: Adenoviridae; Adenovirus Infections, Human; Antineoplastic Agents; Bronchoalveolar Lavage Fluid; Cidofovir; Cytosine; DNA, Viral; Drug Therapy, Combination; Fatal Outcome; Haemophilus influenzae; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Tomography, X-Ray Computed; Trimethoprim, Sulfamethoxazole Drug Combination | 2018 |
Intravesicular cidofovir for BK hemorrhagic cystitis in pediatric patients after hematopoietic stem cell transplant.
Topics: Administration, Intravesical; Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2018 |
Successful treatment of disseminated adenovirus infection with cidofovir and intravenous immunoglobulin in an infant following heart transplant.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Heart Transplantation; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Infant; Male; Opportunistic Infections; Organophosphonates | 2018 |
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus.
Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication | 2018 |
Feline Herpesvirus 1 and Mycoplasma spp. Conventional PCR Assay Results From Conjunctival Samples From Cats in Shelters With Suspected Acute Ocular Infections.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Antiviral Agents; Cat Diseases; Cats; Cidofovir; Conjunctiva; Cytosine; DNA, Bacterial; DNA, Viral; Eye Infections, Bacterial; Eye Infections, Viral; Herpesviridae Infections; Mycoplasma; Mycoplasma Infections; Ointments; Ophthalmic Solutions; Organophosphonates; Oxytetracycline; Polymerase Chain Reaction; Varicellovirus | 2018 |
Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Humans; Kinetics; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Viral Proteins; Virus Replication | 2019 |
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus.
Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides | 2019 |
Intralesional cidofovir as neoadjuvant therapy in a squamous cell carcinoma of the nail bed.
Topics: Antiviral Agents; Carcinoma, Squamous Cell; Cidofovir; Cytosine; Humans; Injections, Intralesional; Nail Diseases; Neoadjuvant Therapy | 2021 |
A quantitative LC-MS/MS method for the determination of tissue brincidofovir and cidofovir diphosphate in a MuPyV-infected mouse model.
Topics: Animals; Antiviral Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Kidney; Mice; Mice, Inbred C57BL; Organophosphonates; Polyomavirus Infections; Spleen; Tandem Mass Spectrometry | 2021 |
Safety and efficacy of intravenously administered cidofovir in adult haematopoietic cell transplant recipients: a retrospective multicentre cohort study.
Topics: Antiviral Agents; Cidofovir; Cohort Studies; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Retrospective Studies; Transplant Recipients | 2021 |
Topical cidofovir for benign human papillomavirus-associated skin lesions.
Topics: Alphapapillomavirus; Cidofovir; Cytosine; Humans; Organophosphonates; Papillomaviridae; Papillomavirus Infections | 2021 |
Daily low dose intravesical cidofovir for the treatment of BK virus associated hemorrhagic cystitis after allogeneic stem cell transplantation.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Drug-Related Side Effects and Adverse Reactions; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections; Renal Insufficiency; Tumor Virus Infections | 2023 |
Cidofovir-induced anterior uveitis in an allogeneic stem cell transplant recipient.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Polyomavirus Infections; Retrospective Studies; Uveitis, Anterior | 2022 |
Cidofovir for the Treatment of Molluscum Contagiosum Virus.
Topics: Cidofovir; Cytosine; Humans; Molluscum Contagiosum; Molluscum contagiosum virus; Organophosphonates | 2022 |
Assessment of immunomodulation and regulation of cell cycle in epithelium and stroma after Cidofovir injection in patients with recurrent respiratory papillomatosis-Pilot study.
Topics: Antiviral Agents; Cell Cycle; Cidofovir; Cytosine; Epithelium; Humans; Immunomodulation; Laryngeal Neoplasms; Organophosphonates; Papillomavirus Infections; Pilot Projects | 2023 |
Human monkeypox outbreak: Epidemiological data and therapeutic potential of topical cidofovir in a prospective cohort study.
Topics: Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Disease Outbreaks; Humans; Mpox (monkeypox); Organophosphonates; Prospective Studies | 2023 |
NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Topics: Animals; Antiviral Agents; Biological Availability; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Mice; Organophosphonates; Prodrugs | 2023 |
Disulfide-incorporated lipid prodrugs of cidofovir: Synthesis, antiviral activity, and release mechanism.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Humans; Lipids; Micelles; Phosphates; Prodrugs; Vaccinia virus; Vero Cells | 2023 |