Page last updated: 2024-08-24

cidofovir anhydrous and cmx 001

cidofovir anhydrous has been researched along with cmx 001 in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (17.86)	29.6817
2010's	16 (57.14)	24.3611
2020's	7 (25.00)	2.80

Authors

Authors	Studies
Beadle, JR; Ciesla, SL; Hartline, C; Hostetler, KY; Keith, KA; Kern, ER; Wan, WB	1
Hruby, DE; Jordan, R; Keith, KA; Kern, ER; Painter, GR; Prichard, MN; Quenelle, DC; Robertson, A	1
Beadle, JR; Collins, DJ; Herrod, BP; Hostetler, KY; Keith, KA; Kern, ER; Quenelle, DC; Trahan, J	1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E	1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Almond, M; Buller, RM; Lampert, B; Oberle, C; Painter, G; Parker, S; Robertson, A; Touchette, E; Trost, LC	1
Godkin, S; Lampert, B; Painter, G; Painter, W; Robertson, A; Trost, LC	1
Alfson, ED; Awosika, OO; Ciarlini, P; Drew, C; Folkerth, RD; Johnson, EL; Klein, JP; Koo, S; Lyons, JL; Marty, F; Phillips, RE; Zaki, S	1
Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN	1
Damon, IK; Foster, S; Gates, I; Lanier, ER; Li, Y; Olson, VA; Smith, SK; Trost, LC	1
Buller, RM; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B	1
Foster, SA; Godin, SJ; Keilholz, L; Khouri, J; Long, J; Rose, ML; Trost, LC	1
Toth, K; Wold, WS	1
Albariño, C; Dyall, J; Flint, M; Foster, S; Hensley, LE; Lanier, ER; McMullan, LK; Nichol, ST; Olinger, GG; Sethna, P; Spiropoulou, CF	1
Chou, S; Ercolani, RJ; Lanier, ER	1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S	1
Hayden, RT; Ison, MG	1
Green, M; Lopez, SMC; Michaels, MG	1
DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P	1
Bae, A; Bambara, RA; Chamberlain, JM; Dewhurst, S; Lanier, R; Sethna, P; Sortino, K	1
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG	1
Cottrell, ML; Dunn, JA; Guzman, BB; Schauer, AP; Sykes, C	1
Sassine, J; Siegrist, EA	1
Hirano, D; Ishikane, M; Kataoka, Y; Kuroda, N; Shimizu, T	1
Akhtar, N; Al-Tammemi, AB; Al-Tawfiq, JA; Chatterjee, C; Chattu, VK; Dwivedi, P; Mohanty, A; Nowrouzi-Kia, B; Padhi, BK; Pradhan, A; Rodriguez-Morales, AJ; Sah, R; Satapathy, P; Shamim, MA; Tripathy, S; Veeramachaneni, SD	1
Bechtel, M; Bojkova, D; Ciesek, S; Cinatl, J; Corman, VM; Göttig, S; Kandler, JD; Kippenberger, S; Michaelis, M; Rabenau, HF; Rothenburger, T; Schneider, J; Steinhorst, K; Tietgen, M; Wass, MN; Zöller, N	1
Bansal, N; Bansal, S; Chaudhay, R; Gujjar, P; Gupta, S; Verma, I	1

Reviews

5 review(s) available for cidofovir anhydrous and cmx 001

Article	Year
Adenovirus. Microbiology spectrum, 2016, Volume: 4, Issue:4 Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Diagnostic Tests, Routine; Disease Susceptibility; Drug Monitoring; Humans; Immunocompromised Host; Organophosphonates	2016
Adenovirus infection in pediatric transplant recipients: are effective antiviral agents coming our way? Current opinion in organ transplantation, 2018, Volume: 23, Issue:4 Topics: Adenoviridae Infections; Antiviral Agents; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Pediatrics; Transplant Recipients	2018
Antivirals With Activity Against Mpox: A Clinically Oriented Review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 01-06, Volume: 76, Issue:1 Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Monkeypox virus; Mpox (monkeypox); Organophosphonates	2023
Lack of clinical evidence of antiviral therapy for human monkeypox: A scoping review. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:2 Topics: Antiviral Agents; Benzamides; Cidofovir; Humans; Mpox (monkeypox)	2023
The use of antivirals in the treatment of human monkeypox outbreaks: a systematic review. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023, Volume: 127 Topics: Antiviral Agents; Benzamides; Cidofovir; Disease Outbreaks; Humans; Isoindoles; Monkeypox virus; Mpox (monkeypox); Trifluridine	2023

Trials

1 trial(s) available for cidofovir anhydrous and cmx 001

Article	Year
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Biological Availability; Capsule Endoscopy; Cidofovir; Cytosine; DNA Viruses; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intraocular Pressure; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Placebos; United States	2012

Article

Year

First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.

Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Biological Availability; Capsule Endoscopy; Cidofovir; Cytosine; DNA Viruses; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intraocular Pressure; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Placebos; United States

2012

Other Studies

22 other study(ies) available for cidofovir anhydrous and cmx 001

Article	Year
Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses. Journal of medicinal chemistry, 2006, Mar-23, Volume: 49, Issue:6 Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; Esters; Humans; Organophosphonates; Orthopoxvirus; Stereoisomerism; Structure-Activity Relationship	2006
Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antiviral Agents; Benzamides; Cells, Cultured; Chlorocebus aethiops; Cowpox virus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Orthopoxvirus; Poxviridae Infections; Treatment Outcome; Vaccinia virus; Vero Cells; Virus Replication	2007
Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cowpox; Kidney; Liver; Lung; Mice; Molecular Structure; Organophosphonates; Spleen; Vaccinia virus	2007
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship	2009
New prodrugs of Adefovir and Cidofovir. Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11 Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus	2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model. Antiviral research, 2008, Volume: 77, Issue:1 Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Ectromelia virus; Ectromelia, Infectious; Ether; Female; Hepatocytes; Humans; Mice; Mice, Inbred A; Organophosphonates	2008
Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient. Neurology, 2013, Apr-30, Volume: 80, Issue:18 Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Encephalomyelitis; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic, T-Cell; Middle Aged; Organophosphonates	2013
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA	2013
In vitro efficacy of brincidofovir against variola virus. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9 Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Organophosphonates; Smallpox; Variola virus	2014
Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model. Antiviral research, 2014, Volume: 112 Topics: Adenoviridae Infections; Adenoviruses, Human; Alanine Transaminase; Animals; Body Weight; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load	2014
The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease. Antiviral research, 2015, Volume: 117 Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Injections, Intradermal; Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia; Vaccinia virus; Variola virus	2015
New drug on the horizon for treating adenovirus. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:14 Topics: Adenoviridae Infections; Adenoviruses, Human; Adoptive Transfer; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Immunocompromised Host; Organophosphonates; T-Lymphocytes	2015
The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus. Antiviral research, 2016, Volume: 125 Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Hemorrhagic Fever, Ebola; Human Umbilical Vein Endothelial Cells; Humans; Lipids; Male; Organophosphonates; Structure-Activity Relationship; Vero Cells; Virus Replication	2016
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins	2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5 Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load	2016
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus. Antiviral research, 2018, Volume: 158 Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication	2018
Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1 Topics: Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Humans; Kinetics; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Viral Proteins; Virus Replication	2019
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus. Antiviral research, 2019, Volume: 172 Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides	2019
A quantitative LC-MS/MS method for the determination of tissue brincidofovir and cidofovir diphosphate in a MuPyV-infected mouse model. Biomedical chromatography : BMC, 2021, Volume: 35, Issue:5 Topics: Animals; Antiviral Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Kidney; Mice; Mice, Inbred C57BL; Organophosphonates; Polyomavirus Infections; Spleen; Tandem Mass Spectrometry	2021
Repurposing of the antibiotic nitroxoline for the treatment of mpox. Journal of medical virology, 2023, Volume: 95, Issue:3 Topics: Anti-Bacterial Agents; Antiviral Agents; Cidofovir; Drug Repositioning; Humans; Mpox (monkeypox); Nitroquinolines	2023
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans. Current drug targets, 2023, Volume: 24, Issue:13 Topics: Animals; Antiviral Agents; Benzamides; Cidofovir; Humans; Monkeypox virus; Mpox (monkeypox); Vaccines	2023