Page last updated: 2024-08-24

cidofovir anhydrous and acyclovir

cidofovir anhydrous has been researched along with acyclovir in 171 studies

Research

Studies (171)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.58)18.7374
1990's31 (18.13)18.2507
2000's66 (38.60)29.6817
2010's60 (35.09)24.3611
2020's13 (7.60)2.80

Authors

AuthorsStudies
Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR1
Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M1
Schneller, SW; Seley, KL; Wu, J1
Andrei, G; De Clercq, E; Froeyen, M; Hendrix, C; Herdewijn, P; Snoeck, R; Wang, J1
Andrei, G; Balzarini, J; Castro, A; De Clercq, E; Gil, C; Martinez, A; Otero, J; Perez, C; Prieto, C; Snoeck, R1
Andrei, G; De Clercq, E; Dimas, K; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Pannecouque, C; Snoeck, R; Stamatiou, G; Witvrouw, M; Zoidis, G1
De Clercq, E; Garuti, L; Roberti, M1
Balzarini, J; Barral, K; Camplo, M; De Clercq, E; Hider, RC; Neyts, J2
Andrei, G; Balzarini, J; Barbarić, M; Cetina, M; De Clercq, E; Frković, D; Kralj, M; Mintas, M; Nagl, A; Opacić, N; Pavelić, K; Raić-Malić, S; Snoeck, R; Zorc, B1
Andrei, G; Balzarini, J; De Clercq, E; García-López, MT; Gerona-Navarro, G; González-Muñiz, R; Pérez de Vega, MJ; Snoeck, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
De Clercq, E; Glapski, C; Guillerm, G; Muzard, M; Pilard, S1
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pískala, A; Snoeck, R1
Chattopadhyay, D; Fan, X; Harden, EA; Johnson, MP; Keith, KA; Kern, ER; Luo, M; McBrayer, A; Prichard, MN; Qiu, S; Torrence, PF1
Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE1
Andrei, G; Balzarini, J; Cristofoli, WA; De Clercq, E; Knaus, EE; Snoeck, R; Wiebe, LI1
Balzarini, J; Clercq, ED; Kralj, M; Makuc, D; Mintas, M; Pavelić, K; Plavec, J; Prekupec, S; Raić-Malić, S; Suman, L1
De Clercq, E; Küçükgüzel, I; Küçükgüzel, SG; Rollas, S; Tatar, E1
Andrei, G; Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Mintas, M; Pavelić, K; Raić-Malić, S; Snoeck, R; Sokcević, M; Suman, L1
Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB1
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Snoeck, R1
Lombardo, F; Obach, RS; Waters, NJ1
Andrei, G; Balzarini, J; Camarasa, MJ; de Castro, S; Naesens, L; Peromingo, MT; Snoeck, R; Velázquez, S1
Allouchi, H; Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Andrei, G; Balzarini, J; Camarasa, MJ; De Castro, S; García-Aparicio, C; Snoeck, R; Velázquez, S1
Andrei, G; Bayrak, OF; De Clercq, E; Güniz Küçükgüzel, S; Karakuş, S; Küçükgüzel, I; Pannecouque, C; Sahin, F; Snoeck, R1
Andrei, G; De Clercq, E; Golankiewicz, B; Ostrowski, T; Snoeck, R1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Daily, SL; Frederick, SL; Harden, EA; Hartline, CB; Jefferson, G; Kern, ER; Maddry, JA; Prichard, MN; Quenelle, DC; Secrist, JA; Tiwari, KN; Whitley, RJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Andrei, G; De Clercq, E; Fan, X; Feng, D; Loiseau, PM; Qu, Y; Snoeck, R; Wang, J; Zhang, X1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Andrei, G; Balzarini, J; Brehová, P; Cihlar, T; De Clercq, E; Dracínský, M; Holý, A; Hui, H; Krecmerová, M; Laflamme, G; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Pomeisl, K; Snoeck, R; Tichý, T1
Agrofoglio, LA; Alexandre, JA; Andrei, G; Azzouzi, A; Balzarini, J; Broggi, J; Caillat, C; Deville-Bonne, D; El-Amri, C; Eriksson, S; Lin, J; Meyer, P; Pradère, U; Roy, V; Snoeck, R; Topalis, D1
Agrofoglio, LA; Andrei, G; Balzarini, J; Montagu, A; Roy, V; Snoeck, R1
Kesel, AJ1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T1
Andrei, G; Balzarini, J; Karlsson, A; McGuigan, C; Persoons, L; Quintiliani, M; Snoeck, R; Solaroli, N1
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R1
Borysko, KZ; Breitenbach, JM; Collins, M; Drach, JC; Hilfinger, JM; Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Serpi, M; Zakharova, VM1
Balzarini, J; Głowacka, IE; Piotrowska, DG1
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K1
Agrofoglio, LA; Andrei, G; Balzarini, J; Roy, V; Sari, O; Snoeck, R1
Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Snoeck, R; Tichý, T1
Agrofoglio, LA; Andrei, G; Balzarini, J; Hamada, M; Montagu, A; Pradère, U; Roy, V; Sari, O; Snoeck, R1
Batta, G; Bereczki, I; Borbás, A; Fejes, Z; Herczegh, P; Kiss-Szikszai, A; Naesens, L; Ostorházi, E; Rőth, E; Rozgonyi, F; Sipos, A; Török, Z1
Alvarez, K; Balzarini, J; Canard, B; Fournier, M; Payrot, N; Priet, S; Roux, L; Weck, C; Zoulim, F1
Balzarini, J; Chibale, K; Kaur, H; Singh, K1
Balzarini, J; Singh, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Briguglio, I; Carta, A; Corona, P; Farci, P; Giliberti, G; Ibba, C; La Colla, P; Loddo, R; Loriga, M; Paglietti, G; Piras, S; Sanna, G1
Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R1
Andrei, G; Babkov, DA; Chizhov, AO; Khandazhinskaya, AL; Novikov, MS; Seley-Radtke, KL; Snoeck, R1
Briguglio, I; Carta, A; Corona, P; Farci, P; Fermeglia, M; Gavini, E; Giliberti, G; Giunchedi, P; Ibba, C; La Colla, P; Laurini, E; Loddo, R; Piras, S; Pricl, S; Sanna, G1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrei, G; Balzarini, J; Bertamino, A; Campiglia, P; Ciaglia, T; di Sarno, V; Gomez-Monterrey, IM; Musella, S; Novellino, E; Ostacolo, C; Sala, M; Scala, MC; Snoeck, R; Spensiero, A1
Aldern, KA; Beadle, JR; Broker, TR; Buckheit, RW; Chow, LT; Harden, EA; Hartman, T; Hostetler, KY; Keith, KA; Prichard, MN; Valiaeva, N; Yang, G; Yu, JH1
Andronova, VL; Charushin, VN; Denisova, AO; Galegov, GA; Kayushin, AL; Kharitonova, MI; Konstantinova, ID; Kotovskaya, SK; Miroshnikov, AI1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R1
Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Pomeisl, K; Snoeck, R1
Andrei, G; De Jonghe, S; Herdewijn, P; Lescrinier, E; Plebanek, E; Snoeck, R1
Agrofoglio, LA; Andrei, G; Bessières, M; Chartier, A; Hervin, V; Lohier, JF; Roy, V; Snoeck, R1
Andrei, G; De Jonghe, S; Herdewijn, P; Liu, C; Snoeck, R; Srivastava, P; Wang, M1
Andrei, G; De Jonghe, S; Groaz, E; Herdewijn, P; Luo, M; Snoeck, R1
Andrei, G; Pertusati, F; Pileggi, E; Schols, D; Serpi, M; Snoeck, R1
Andrei, G; Hulpia, F; Liekens, S; Noppen, S; Schols, D; Snoeck, R; Van Calenbergh, S; Vervaeke, P1
Claessens, F; Dehaen, W; Helsen, C; Karypidou, K; Pannecouque, C; Persoons, L; Quevedo, MA; Ribone, SR1
Abdel-Moty, SG; Andrei, G; Hayallah, AM; Mohammed, AF; Simons, C; Snoeck, R1
Andrei, G; Cazin, I; Harej, A; Klobučar, M; Macan, AM; Pavelić, K; Pavelić, SK; Raić-Malić, S; Schols, D; Snoeck, R; Stepanić, V1
Balzarini, J; De Clercq, E; Karki, SS; Kulkarni, AA; Kumar, S; Veliyath, SK1
Andrei, G; Groaz, E; Herdewijn, P; Luo, M; Snoeck, R1
Andrei, G; De Jonghe, S; Groaz, E; Herdewijn, P; Snoeck, R; Zheng, Z1
Andrei, G; Aralov, AV; Belyaev, ES; Chistov, AA; Ishmukhametov, AA; Jegorov, AV; Korshun, VA; Kozlovskaya, LI; Matyugina, ES; Nikolaeva, YV; Osolodkin, DI; Shtro, AA; Snoeck, R; Volok, VP1
Boryczka, S; Chrobak, E; Orzechowska, B; Pęcak, P1
Andrei, G; D'Alonzo, D; De Fenza, M; Esposito, A; Guaragna, A; Snoeck, R; Talarico, G1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Andrei, G; De Clercq, E; Desmyter, J; Goubau, P; Snoeck, R1
Kern, ER1
De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R1
De Clercq, E; Holý, A1
Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF1
Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G1
Davidson, JM; Drew, WL; Fisher, PE; Glutzer, E; Jaffe, HS; Lalezari, JP; Miner, D; Owen, WF; Safrin, S1
Bravo, FJ; Kern, ER; Kier, AB; Stanberry, LR; Vogt, PE1
De Clercq, E2
Barkhimer, DB; Chen, MS; Mendel, DB1
Reusser, P1
Andrei, G; De Clercq, E; Snoeck, R2
Cassady, KA; Whitley, RJ1
Ganem, D; Kedes, DH1
Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG1
Boggs, J; Cheung, T; Corey, L; Drew, WL; Feinberg, J; Gathe, J; Jaffe, HS; Kessler, H; Kramer, F; Lalezari, J; Lee, S; McGuire, B; Safrin, S; Schacker, T1
Luks-Golger, DB; Martinez, CM1
De Clercq, E; Neyts, J1
Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY1
Kaufman, HE; Thompson, HW; Varnell, ED1
Don, PC; Kaufmann, M; Lateef, F; Weinberg, JM; White, SM1
Bartels, SP; Gordon, YJ; Romanowski, EG1
Afouna, MI; DeClercq, E; El-Shattawy, HH; Ghanem, AH; Higuchi, WI; Kern, ER; Mehta, SC1
Keating, MR1
Einsele, H; Hebart, H1
Aymard, M; Chen, Y; Devergie, A; Espérou, H; Garderet, L; Garrait, V; Gluckman, E; Hocqueloux, L; Leleu, G; Molina, JM; Morfin, F; Morinet, F; Ribaud, P; Rocha, V; Scieux, C; Sélimi, F; Socié, G; Thouvenot, D1
Blot, N; Dehesdin, D; Janvresse, C; Schneider, P; Tron, P; Vannier, JP; Young, P1
Eizuru, Y; Minamishima, Y; Minematsu, T; Mori, S1
Torres, G1
Bowers, M1
Fujiwara, T; Kaneko, H; Mori, S; Shigeta, S1
Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V1
Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K1
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B1
De Clercq, E; Naesens, L1
Geusau, A; Kopp, T; Rieger, A; Stingl, G1
Snoeck, R1
Zaia, JA2
De Clercq, E; Kurane, I; Maeda, A; Morikawa, S; Niikura, M; Saijo, M; Suzutani, T1
Emery, VC; Leśnikowski, ZJ; Olejniczak, A; Paradowska, E; Przepiórkiewicz, M1
Morfin, F; Thouvenot, D1
Afouna, MI; Fincher, TK; Reddy, IK; Zaghloul, AA1
Bidanset, DJ; Kern, ER; Kushner, NL; Long, MC; Williams, SL1
Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW1
Chilukuri, S; Rosen, T1
Boeckh, M; Nichols, WG; Papanicolaou, G; Rubin, R; Wingard, JR; Zaia, J1
Eksborg, S1
Lajusticia, J; Ramos, C1
Clarke, HE; Maggs, DJ1
De Clercq, E; Friedrichs, C; Gaspar, G; Neyts, J; Wutzler, P1
Dediulescu, DF; Dediulescu, L1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM1
Goh, CL; Tan, HH1
Alessi, E; Cusini, M; Ghislanzoni, M; Zerboni, R1
Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K1
Challacombe, SJ; Woo, SB1
Andrei, G; De Clercq, E; Fiten, P; Gordts, B; Goubau, P; Opdenakker, G; Selleslag, D; Snoeck, R; van Landuyt, H1
Boivin, G; Sergerie, Y1
Cieśluk, B; Dzieciatkowski, T; Majewska, A; Łuczak, M1
Járay, J; Péter, A; Telkes, G; Varga, M1
Cowan, MJ; Dvorak, CC; Horn, B; Weintrub, PS1
Bernardin, R; Castelo-Soccio, L; Goldstein, SA; Kovarik, C; Stern, J1
Deinhardt, S; Sauerbrei, A; Wutzler, P; Zell, R1
Beer, M; Eyrich, M; Gattenlöhner, S; Girschick, HJ; Liese, J; Schick, J; Schlegel, PG; Weissbrich, B; Wiegering, V1
Bahar, MS; Boltežar, IH; Gale, N; Matičič, M; Poljak, M; Zargi, M1
Bohn, K; Hamprecht, K; Heim, A; Hoffmann, D; Hofmann, J; Jahn, G; Sauerbrei, A; Schnitzler, P; Weissbrich, B; Wutzler, P; Zell, R1
Evans, KG; Goldstein, SC; Kim, EJ; Morrissey, KA; Rook, AH; Vittorio, CC1
Armistead, P; Dean, A; Khan, T; Muluneh, B1
Bastide, C; Bruyère, F; Chandenier, J; Desoubeaux, G; Fourcade, C; Guy, L; Karsenty, G; Lachaud, L; Lavigne, JP; Malavaud, S; Sotto, A1
Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D1
Boivin, G; Piret, J1
de Alencastro, RB; de Souza, FR; França, TC; Gonçalves, AS; Guimarães, AP; Oliveira, AA; Ramalho, TC1
Andronova, VL; Deryabin, PG; Galegov, GA; Jasko, MV; Kukhanova, MK; Skoblov, YS1
Fort, MW; Ledbetter, EC; Pennington, MR; Van de Walle, GR1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S1
Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY1
Rosen, T1
Guo, HM; Li, JP; Qin, T; Qu, GR; Xie, MS1
Dhillon, VK; Kumar, PN; Mathur, A; Yang, CQ1
Giannasca, NJ; Greeley, ZW; Margulies, BJ; Porter, MJ1
Heidenreich, D; Hofmann, WK; Jawhar, M; Klein, SA; Kreil, S; Mueller, N; Nolte, F1
Baukmann, S; Brunnemann, AK; Bühler, S; Fickenscher, H; Krumbholz, A; Rose, R; Sauerbrei, A; Zell, R1
Chou, S1
Fan, J; Kashemirov, BA; Liu, D; Lloyd, MG; Lyu, J; McKenna, CE; Moffat, JF; Overhulse, JM; Prichard, MN1
Bouscarat, F; Boutolleau, D; Bucau, M; Burrel, S; Fidouh, N; Ghosn, J; Hachon, L; Joly, V; Khellaf, L; Lariven, S; Le Pluart, D; Thy, M1
Andrei, G; Gillemot, S; Reynders, M; Schalkwijk, HH; Selleslag, D; Snoeck, R1

Reviews

24 review(s) available for cidofovir anhydrous and acyclovir

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
    Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3

    Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication

1991
Antivirals for the treatment of herpesvirus infections.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32 Suppl A

    Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds

1993
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options.
    The Journal of hospital infection, 1996, Volume: 33, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

1996
New therapeutic approaches to the alphaherpesvirus infections.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

1997
Cidofovir use in acyclovir-resistant herpes infection.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1997
Antiviral agents for non-human immunodeficiency virus infections.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir

1999
Cytomegalovirus infection following stem cell transplantation.
    Haematologica, 1999, Volume: 84 Suppl EHA-4

    Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency

1999
Recent developments in herpesvirus therapy.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine

2001
[Perspectives for the treatment and prevention of herpes simplex infections].
    Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:4 Pt 2

    Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Famciclovir; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Imiquimod; Interferon Inducers; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

2002
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2002, Volume: 29, Issue:8

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors

2002
[Drugs against human cytomegalovirus].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:75

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drugs, Investigational; Female; Foscarnet; Ganciclovir; Global Health; Humans; Infectious Disease Transmission, Vertical; Naphthalenesulfonates; Organophosphonates; Organophosphorus Compounds; Pregnancy; Pregnancy Complications, Infectious; Thionucleotides; Valacyclovir; Valganciclovir; Valine

2002
Herpes simplex virus resistance to antiviral drugs.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Herpes Simplex; Humans; Immunocompromised Host; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins; Virus Replication

2003
Management of acyclovir-resistant herpes simplex virus.
    Dermatologic clinics, 2003, Volume: 21, Issue:2

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine

2003
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2003, Volume: 9, Issue:9

    Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunotherapy; Lymphocyte Depletion; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning

2003
The pharmacokinetics of antiviral therapy in paediatric patients.
    Herpes : the journal of the IHMF, 2003, Volume: 10, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases

2003
[Antiherpetic therapy].
    Oftalmologia (Bucharest, Romania : 1990), 2005, Volume: 49, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine

2005
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies.
    American journal of clinical dermatology, 2006, Volume: 7, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Schedule; Epstein-Barr Virus Infections; Famciclovir; Foscarnet; Herpes Zoster; Herpesviridae Infections; Humans; Immunocompromised Host; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Trifluridine; Valacyclovir; Valine

2006
Management of recurrent oral herpes simplex infections.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103 Suppl

    Topics: Acyclovir; Antiviral Agents; Bell Palsy; Cidofovir; Cytosine; Erythema Multiforme; Herpes Labialis; Humans; Immunocompromised Host; Organophosphonates; Secondary Prevention; Sunscreening Agents; Time Factors; Valacyclovir; Valine

2007
The discovery of antiviral agents: ten different compounds, ten different stories.
    Medicinal research reviews, 2008, Volume: 28, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases

2008
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
    Orvosi hetilap, 2008, Dec-21, Volume: 149, Issue:52

    Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir

2008
[Non-antibiotic anti-infectious treatments in urology].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:15

    Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir

2013
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
    Reviews in medical virology, 2014, Volume: 24, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates

2014

Trials

2 trial(s) available for cidofovir anhydrous and acyclovir

ArticleYear
A randomized, double-blind, placebo-controlled trial of cidofovir gel for the treatment of acyclovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDS.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Double-Blind Method; Drug Resistance, Microbial; Female; Foscarnet; Gels; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1997
Opportunistic infection highlights from the 35th ICAAC.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia

1995

Other Studies

145 other study(ies) available for cidofovir anhydrous and acyclovir

ArticleYear
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1989
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells

1996
Carbocyclic oxetanocins lacking the C-3' methylene.
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses

1997
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Antiviral Agents; Cyclohexanes; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Models, Molecular; Molecular Mimicry; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship

2000
Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
    Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Benzothiadiazines; Chlorocebus aethiops; Cyclic S-Oxides; Cytomegalovirus; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; T-Lymphocytes; Vero Cells

2000
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
    Bioorganic & medicinal chemistry letters, 2002, Mar-11, Volume: 12, Issue:5

    Topics: Bacteria; Cell Division; Cell Line; Formazans; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazolium Salts; Thiosemicarbazones; Tumor Cells, Cultured; Viruses

2002
Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles.
    Bioorganic & medicinal chemistry letters, 2002, Oct-07, Volume: 12, Issue:19

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Structure-Activity Relationship; T-Lymphocytes; Tumor Cells, Cultured; Viral Plaque Assay

2002
Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives.
    Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24

    Topics: Antiviral Agents; Deferiprone; Dideoxynucleosides; Drug Design; Herpesvirus 1, Human; Models, Molecular; Pyridones; Structure-Activity Relationship

2003
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Amino Acids; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Hydantoins; Hydroxyurea; Stereoisomerism; Structure-Activity Relationship

2005
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Alanine; Antiviral Agents; Azetidines; Cells, Cultured; Cytomegalovirus; Humans; Lactams; Protease Inhibitors; Structure-Activity Relationship

2005
Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives.
    Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Chlorocebus aethiops; Deferiprone; HeLa Cells; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; HIV-2; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Pyridones; Structure-Activity Relationship; Vero Cells

2006
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
    Journal of medicinal chemistry, 2006, Feb-23, Volume: 49, Issue:4

    Topics: Adenosylhomocysteinase; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Deoxyadenosines; Herpesvirus 3, Human; Humans; Nucleosides; Stereoisomerism; Structure-Activity Relationship

2006
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
    Journal of medicinal chemistry, 2007, Mar-08, Volume: 50, Issue:5

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA Viruses; Humans; Mice; Organophosphonates; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Triazines

2007
Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Amino Acid Sequence; Antiviral Agents; Herpesviridae; Humans; Kinetics; Molecular Sequence Data; Orthopoxvirus; Phosphorylation; Thymidine Kinase; Vaccinia virus

2007
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells

2007
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
    Journal of medicinal chemistry, 2007, Jun-14, Volume: 50, Issue:12

    Topics: Alkynes; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Transfection; Uridine

2007
Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
    Journal of medicinal chemistry, 2007, Jun-28, Volume: 50, Issue:13

    Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Cytostatic Agents; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Molecular Mimicry; Positron-Emission Tomography; Pyrimidine Nucleosides; Pyrimidines; Structure-Activity Relationship

2007
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:2

    Topics: Animals; Antitubercular Agents; Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Thiourea; Triazoles

2008
Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Pyrimidines; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship

2007
Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cytomegalovirus; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship

2007
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
    Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23

    Topics: Antiviral Agents; Cell Line; Cytosine; DNA Viruses; Drug Resistance, Viral; Esters; Humans; Magnetic Resonance Spectroscopy; Prodrugs; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thymidine; Urea

2008
Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.
    Bioorganic & medicinal chemistry, 2008, Nov-01, Volume: 16, Issue:21

    Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Herpes Zoster; Herpesvirus 3, Human; Humans; Imidazoles; Lung; Molecular Structure; Pyridines; Structure-Activity Relationship

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytomegalovirus; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Naphthalenesulfonates; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Virus Replication

2009
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Sulfonamides; Thiourea; Viruses

2009
Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:8

    Topics: Acyclovir; Antiviral Agents; Cell Line; Guanine; Herpesvirus 3, Human; Humans

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Cells, Cultured; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Fluorescent Antibody Technique, Indirect; Herpesviridae; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Molecular Structure; Pyrimidine Nucleosides; Viral Proteins; Virus Replication

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Antiprotozoal Agents; Antiviral Agents; Cell Line; Humans; Leishmania donovani; Nucleosides; Pyrans; Pyridones; Pyrimidine Nucleosides

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
    Journal of medicinal chemistry, 2010, Oct-14, Volume: 53, Issue:19

    Topics: Adenine; Antiviral Agents; Cell Proliferation; Cells, Cultured; Esters; Herpesviridae; Humans; Organophosphorus Compounds; Poxviridae; Prodrugs; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Virology

2010
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Antiviral Agents; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Herpesviridae; Humans; Ligands; Models, Molecular; Molecular Structure; Nucleoside-Phosphate Kinase; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase

2011
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; Cyclization; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Vero Cells; Viruses

2011
Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Anti-Bacterial Agents; Benzaldehydes; Cell Line, Tumor; Chromatography, Thin Layer; Cytomegalovirus; Hepacivirus; Herpesvirus 3, Human; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Retinoids; Stereoisomerism; Structure-Activity Relationship; Thiosemicarbazones

2011
New prodrugs of Adefovir and Cidofovir.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

2011
Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.
    Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14

    Topics: Amides; Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Floxuridine; Hepacivirus; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Phosphoric Acids; Stereoisomerism; Structure-Activity Relationship; Virus Replication

2011
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses

2011
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
    Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16

    Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus

2011
Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cytostatic Agents; Drug Design; Humans; Inhibitory Concentration 50; Mice; Nucleotides; Triazoles; Viruses

2012
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses

2012
Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; Deoxyuridine; Humans; Inhibitory Concentration 50; Virus Replication; Viruses

2012
Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Animals; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA Viruses; Guanine; Humans; Hypoxanthine; Hypoxanthines; Nucleosides; Organophosphonates; Phosphorous Acids; Prodrugs; Structure-Activity Relationship

2012
Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphono-but-2'-en-1'-yl]purine nucleosides.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; DNA Viruses; Dogs; Drug Design; Drug Discovery; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Organophosphonates; Prodrugs; Purine Nucleosides; RNA Viruses; Vero Cells; Viral Plaque Assay

2012
Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities.
    Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23

    Topics: Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cell Survival; Drug Resistance, Viral; Gram-Positive Bacteria; Herpesvirus 1, Human; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Isoindoles; Microbial Sensitivity Tests; o-Phthalaldehyde; Teicoplanin

2012
Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: synthesis, antiviral activity and decomposition study.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Antiviral Agents; Cell Line, Tumor; Cell Survival; DNA Viruses; Dose-Response Relationship, Drug; Esters; Hepatitis B virus; HIV-1; HIV-2; Humans; Models, Chemical; Molecular Structure; Nucleosides; Organophosphonates; Organothiophosphonates; Prodrugs

2013
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship

2013
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Aminoquinolines; Animals; Antiviral Agents; Cattle; Cell Line; Cell Survival; DNA Viruses; Dogs; Dose-Response Relationship, Drug; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; RNA Viruses; Structure-Activity Relationship

2014
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus

2015
Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.
    Bioorganic & medicinal chemistry, 2015, Nov-01, Volume: 23, Issue:21

    Topics: Acetamides; Antiviral Agents; Cell Line; Cell Proliferation; Cytomegalovirus; DNA Viruses; Drug Evaluation, Preclinical; Herpesvirus 3, Human; Humans; RNA Viruses; Structure-Activity Relationship; Uracil; Virus Replication

2015
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
    European journal of medicinal chemistry, 2015, Nov-13, Volume: 105

    Topics: Antiviral Agents; DNA Viruses; Dose-Response Relationship, Drug; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Quinolines; Quinoxalines; RNA Viruses; Structure-Activity Relationship

2015
Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Antiviral Agents; Cell Line; Cell Proliferation; Cells, Cultured; Drug Design; Herpesvirus 3, Human; Humans; Indoles; Molecular Structure; Virus Replication

2016
Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Guanine; HEK293 Cells; Herpesvirus 2, Human; HIV; Humans; Leukocytes, Mononuclear; Molecular Structure; Nucleic Acid Amplification Techniques; Organophosphonates; Papillomaviridae; Structure-Activity Relationship; Virus Replication

2016
New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1.
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Acyclovir; Antiviral Agents; Benzimidazoles; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Nucleosides; Organophosphonates

2017
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship

2017
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Humans; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Simplexvirus

2017
Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Antiviral Agents; Cell Line; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleosides; Pyrazines; Varicella Zoster Virus Infection; Virus Replication

2018
Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Coronavirus 229E, Human; Dose-Response Relationship, Drug; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Structure-Activity Relationship

2018
Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Antiviral Agents; Cyclopentanes; DNA Viruses; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Organophosphonates; Structure-Activity Relationship

2018
Amidate Prodrugs of Cyclic 9-(
    ACS medicinal chemistry letters, 2018, Apr-12, Volume: 9, Issue:4

    Topics:

2018
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Antiviral Agents; Cell Line; DNA Viruses; Drug Stability; Humans; Nucleosides; Organophosphonates; Prodrugs; RNA Viruses; Structure-Activity Relationship

2018
Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Purine Nucleosides; Small Molecule Libraries; Structure-Activity Relationship; Vaccinia virus

2018
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents.
    Bioorganic & medicinal chemistry letters, 2018, 11-15, Volume: 28, Issue:21

    Topics: Antiviral Agents; Catalytic Domain; Cell Line, Tumor; Coronavirus; Coronavirus 3C Proteases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Triazoles; Viral Proteins

2018
Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.
    Bioorganic & medicinal chemistry, 2019, 03-15, Volume: 27, Issue:6

    Topics: Acyclovir; Antiviral Agents; Guanine; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Models, Molecular

2019
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles; Viruses

2019
Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2013, Volume: 22, Issue:4

    Topics:

2013
Amidate Prodrugs of
    ACS medicinal chemistry letters, 2020, Jul-09, Volume: 11, Issue:7

    Topics:

2020
Influence of 4'-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2.
    ACS medicinal chemistry letters, 2021, Jan-14, Volume: 12, Issue:1

    Topics:

2021
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
    European journal of medicinal chemistry, 2021, Aug-05, Volume: 220

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; DNA Viruses; Dogs; Humans; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Oxazines; SARS-CoV-2; Structure-Activity Relationship; Vero Cells; Virus Replication

2021
Novel betulin dicarboxylic acid ester derivatives as potent antiviral agents: Design, synthesis, biological evaluation, structure-activity relationship and in-silico study.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Antiviral Agents; Dicarboxylic Acids; DNA Viruses; Dose-Response Relationship, Drug; Drug Design; Esters; Microbial Sensitivity Tests; Molecular Structure; RNA Viruses; Structure-Activity Relationship; Triterpenes

2021
Synthesis and antiviral properties of biomimetic iminosugar-based nucleosides.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Antiviral Agents; Biomimetics; Molecular Conformation; Nucleosides; Piperidines

2022
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Comparative activity of various compounds against clinical strains of herpes simplex virus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Dextran Sulfate; Guanine; HeLa Cells; Heparin; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Virus Replication

1992
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
    Journal of virological methods, 1991, Volume: 35, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin

1991
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Peritoneal Cavity; Skin Diseases, Infectious

1991
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus.
    Antiviral research, 1995, Volume: 26, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds

1995
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; DNA Restriction Enzymes; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral; Thymidine Kinase

1994
Treatment with intravenous (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine of acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:3

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1994
Evaluation of HPMPC therapy for primary and recurrent genital herpes in mice and guinea pigs.
    Antiviral research, 1993, Volume: 21, Issue:1

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Herpes Genitalis; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Ultraviolet Rays; Vagina; Vaginal Diseases; Virus Replication

1993
Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:9

    Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Drug Resistance, Microbial; Fibroblasts; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Plaque Assay

1995
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:7

    Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid

1996
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
    The Journal of clinical investigation, 1997, May-01, Volume: 99, Issue:9

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA Probes; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Methylurea Compounds; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Phorbol Esters; Pyridines; Sarcoma, Kaposi; Tumor Cells, Cultured; Valine; Virus Replication

1997
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006

    Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases

1997
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
    AIDS (London, England), 1997, Volume: 11, Issue:11

    Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency

1997
In vitro and in vivo inhibition of murine gamma herpesvirus 68 replication by selected antiviral agents.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Chlorocebus aethiops; Cidofovir; Cytosine; Gammaherpesvirinae; Herpesviridae Infections; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vero Cells; Virus Replication

1998
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds

1998
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine

1998
Treatment of acyclovir-resistant, foscarnet-unresponsive HSV infection with topical cidofovir in a child with AIDS.
    Archives of dermatology, 1998, Volume: 134, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Anti-HIV Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Microbial; Facial Dermatoses; Foscarnet; Herpes Simplex; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Failure

1998
Comparative antiviral efficacies of cidofovir, trifluridine, and acyclovir in the HSV-1 rabbit keratitis model.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:2

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Trifluridine; Virus Replication; Virus Shedding

1999
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:5

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral

1999
Resistant herpes simplex virus type 1 infection: an emerging concern after allogeneic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:4

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Drug Resistance, Microbial; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Transplantation, Homologous

2000
Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant.
    Bone marrow transplantation, 2000, Volume: 26, Issue:8

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance; Female; Foscarnet; Herpes Simplex; Humans; Infant; Organophosphonates; Organophosphorus Compounds

2000
Isolation and analysis of an aciclovir-resistant murine cytomegalovirus mutant.
    Antiviral research, 2001, Volume: 49, Issue:1

    Topics: Acyclovir; Amino Acid Substitution; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Codon; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Ganciclovir; Inhibitory Concentration 50; Mice; Muromegalovirus; Mutation; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Virus Replication

2001
Herpesviruses.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Complementary Therapies; Cytosine; Famciclovir; Foscarnet; Herpesviridae Infections; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine; Viral Vaccines

1995
Acyclovir-resistant herpes: expanded access available for cidofovir gel (Forvade).
    AIDS treatment news, 1997, Feb-07, Issue:No 264

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Gels; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds

1997
[Evaluation of antiviral agents for adenovirus using the MTT method in vitro].
    Nippon Ganka Gakkai zasshi, 2000, Volume: 104, Issue:11

    Topics: Acyclovir; Adenoviridae; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Foscarnet; Humans; Organophosphonates; Organophosphorus Compounds; Zalcitabine

2000
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation.
    Pathologie-biologie, 2001, Volume: 49, Issue:7

    Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Codon; Cytosine; DNA Mutational Analysis; Drug Resistance, Viral; Female; Foscarnet; Graft vs Host Disease; Herpes Simplex; Humans; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Point Mutation; Salvage Therapy; Simplexvirus; Thymidine Kinase; Transplantation, Homologous; Valacyclovir; Valine; Viral Proteins; Virus Activation

2001
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis

2001
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation

2001
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 2002, Feb-04, Volume: 44, Issue:1123

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine

2002
Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient.
    The British journal of dermatology, 2002, Volume: 147, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Fissure in Ano; Herpes Simplex; Herpesvirus 2, Human; Humans; Organophosphonates; Organophosphorus Compounds

2002
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Oct-15, Volume: 35, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine

2002
Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain.
    Antiviral research, 2002, Volume: 56, Issue:3

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Blotting, Western; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Herpesvirus 1, Human; Molecular Sequence Data; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA; Thymidine Kinase; Vero Cells; Viral Plaque Assay

2002
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice.
    International journal of pharmaceutics, 2003, Mar-06, Volume: 253, Issue:1-2

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Topical; Animals; Antiviral Agents; Azepines; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Permeability; Skin Absorption

2003
Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry.
    Antiviral research, 2003, Volume: 58, Issue:2

    Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds

2003
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
    Antiviral research, 2003, Volume: 58, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds

2003
[Infection due to acyclovir-resistant varicella-zoster herpes virus in a patient with AIDS].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fatal Outcome; Female; Foscarnet; Herpes Zoster; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Organophosphonates

2004
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
    American journal of veterinary research, 2004, Volume: 65, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication

2004
Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
    Antiviral research, 2004, Volume: 62, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction

2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
    Antiviral research, 2004, Volume: 61, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins

2004
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    The Journal of general virology, 2005, Volume: 86, Issue:Pt 8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication

2005
Chronic hypertrophic acyclovir-resistant genital herpes treated with topical cidofovir and with topical foscarnet at recurrence in an HIV-positive man.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:7

    Topics: Acyclovir; Administration, Topical; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Herpes Genitalis; HIV Infections; Humans; Male; Middle Aged; Organophosphonates

2006
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
    Veterinary microbiology, 2007, May-16, Volume: 122, Issue:1-2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates

2007
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:2

    Topics: Acyclovir; Adolescent; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections

2007
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes.
    Antiviral research, 2008, Volume: 77, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Combinations; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Hydroxyurea; Mutation; Organophosphonates; Ribonucleotide Reductases; Thymidine Kinase

2008
[In vitro acyclovir and cidofovir susceptibilities of human herpesvirus type 1 clinical isolates].
    Medycyna doswiadczalna i mikrobiologia, 2008, Volume: 60, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Herpes Simplex; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Vero Cells

2008
Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Oct-15, Volume: 49, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Male; Organophosphonates; Simplexvirus; Stem Cell Transplantation; Stomatitis; Treatment Outcome

2009
Successful treatment of acyclovir-resistant herpes simplex virus with intralesional cidofovir.
    Archives of dermatology, 2010, Volume: 146, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Facial Dermatoses; Herpes Simplex; Humans; Injections, Intralesional; Male; Organophosphonates

2010
Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus.
    Antiviral research, 2010, Volume: 86, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Mutation, Missense; Organophosphonates; Oxidation-Reduction; Sequence Analysis, DNA; Staining and Labeling; Tetrazolium Salts; Thymidine Kinase; Viral Proteins

2010
Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis.
    BMC pediatrics, 2011, May-10, Volume: 11

    Topics: Acyclovir; Antiviral Agents; Chickenpox; Child; Child, Preschool; Cidofovir; Cytosine; Female; Herpes Zoster; Herpesvirus 3, Human; Hospitalization; Humans; Immunocompromised Host; Incidence; Infant; Male; Organophosphonates; Practice Guidelines as Topic

2011
Adjuvant therapy for laryngeal papillomatosis.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2011, Volume: 20, Issue:3

    Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antiviral Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Indoles; Infant; Laryngeal Diseases; Male; Middle Aged; Organophosphonates; Papilloma; Papillomavirus Vaccines; Vaccination; Valacyclovir; Valine

2011
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins

2011
Chronic acyclovir-resistant HSV-2 ulcer in an immunosuppressed patient treated with topical cidofovir.
    Archives of dermatology, 2011, Volume: 147, Issue:12

    Topics: Acyclovir; Administration, Cutaneous; Aged; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fissure in Ano; Herpesvirus 2, Human; Humans; Immunocompromised Host; Lymphoma, Mantle-Cell; Male; Organophosphonates; Stem Cell Transplantation

2011
Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:2

    Topics: Acyclovir; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Gels; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Real-Time Polymerase Chain Reaction; Transplantation, Homologous; Treatment Outcome

2013
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Follow-Up Studies; Foscarnet; Herpes Simplex; HIV Infections; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Retrospective Studies; Skin Diseases, Viral; Skin Ulcer; Socioeconomic Factors; Thymidine Kinase; Treatment Outcome

2014
Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox.
    European journal of medicinal chemistry, 2015, Feb-16, Volume: 91

    Topics: Acyclovir; Antiviral Agents; Catalytic Domain; Cidofovir; Cytosine; Drug Design; Humans; Kinetics; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Nucleoside-Phosphate Kinase; Organophosphonates; Small Molecule Libraries; Smallpox; Species Specificity; Structure-Activity Relationship; Thermodynamics; Variola virus; Viral Proteins

2015
[Research of suppression of the herpes simplex virus reproduction with drug resistance by combination phosphite of acycloguanosine with some antiherpetic drugs].
    Voprosy virusologii, 2014, Volume: 59, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Foscarnet; Glycyrrhizic Acid; Herpesvirus 1, Human; Humans; Interferon-alpha; Organophosphonates; Phosphites; Ribavirin; Vero Cells; Vidarabine; Virus Replication

2014
A novel corneal explant model system to evaluate antiviral drugs against feline herpesvirus type 1 (FHV-1).
    The Journal of general virology, 2016, Volume: 97, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cidofovir; Cornea; Cytosine; Drug Evaluation, Preclinical; Organ Culture Techniques; Organophosphonates; Varicellovirus; Virus Cultivation

2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load

2016
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5

    Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles

2017
Recurrent Herpes Labialis in Adults: New Tricks for an Old Dog.
    Journal of drugs in dermatology : JDD, 2017, Mar-01, Volume: 16, Issue:3

    Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Labialis; Herpesvirus 1, Human; Humans; Hyperthermia, Induced; Infusions, Parenteral; Organophosphonates; Recurrence; Stomatitis, Herpetic; Viral Load

2017
Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir.
    The Journal of organic chemistry, 2018, 12-21, Volume: 83, Issue:24

    Topics: Acyclovir; Chemistry Techniques, Synthetic; Cidofovir; Hydroxylation; Models, Molecular; Molecular Conformation; Nucleosides; Stereoisomerism

2018
Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass.
    The Annals of otology, rhinology, and laryngology, 2019, Volume: 128, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Herpes Simplex; Humans; Injections, Intralesional; Laryngitis; Male; Middle Aged

2019
Acyclovir, cidofovir, and amenamevir have additive antiviral effects on herpes simplex virus TYPE 1.
    Antiviral research, 2020, Volume: 176

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Drug Resistance, Viral; Drug Synergism; Herpesvirus 1, Human; Inhibitory Concentration 50; Oxadiazoles; Vero Cells; Virus Replication

2020
Topical Treatment of Acyclovir-Resistant Herpes Simplex Virus Stomatitis after Allogeneic Hematopoietic Cell Transplantation.
    Oncology research and treatment, 2020, Volume: 43, Issue:12

    Topics: Acyclovir; Administration, Topical; Adult; Aged; Antiviral Agents; Cidofovir; Drug Resistance, Viral; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Stomatitis; Treatment Outcome

2020
Antiviral susceptibility of recombinant Herpes simplex virus 1 strains with specific polymerase amino acid changes.
    Antiviral research, 2021, Volume: 195

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Guanine; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Microbial Sensitivity Tests; Thymidine Kinase; Vero Cells

2021
Opposite effects of cytomegalovirus UL54 exonuclease domain mutations on acyclovir and cidofovir susceptibility.
    Antiviral research, 2021, Volume: 195

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Ganciclovir; Mutation; Viral Proteins

2021
An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice.
    Antiviral research, 2022, Volume: 199

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Herpesvirus 3, Human; Humans; Mice; Organ Culture Techniques; Organophosphonates; Prodrugs; Viral Regulatory and Accessory Proteins

2022
Novel mutations in antiviral multiresistant HSV-2 genital lesion: A case report.
    Journal of medical virology, 2022, Volume: 94, Issue:12

    Topics: Acyclovir; Antiviral Agents; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Genitalia; Herpes Simplex; Herpesvirus 2, Human; Humans; Imiquimod; Mutation; Obesity; Thymidine Kinase; Valacyclovir

2022
Heterogeneity and viral replication fitness of HSV-1 clinical isolates with mutations in the thymidine kinase and DNA polymerase.
    The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11

    Topics: Acyclovir; Antiviral Agents; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Mutation; Thymidine Kinase; Virus Replication

2022