ci 994 and vorinostat
ci 994 has been researched along with vorinostat in 14 studies
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Belosay, A; Gediya, LK; Khandelwal, A; Njar, VC; Purushottamachar, P | 1 |
| Bradner, JE; Grachan, ML; Greenberg, EF; Haggarty, SJ; Mazitschek, R; Warnow, T; West, N | 1 |
| Bertrand, P; Blanquart, C; Bouchet, S; Cuendet, M; Lehotzky, A; Martinet, N; Nurisso, A; Ovadi, J; Simões-Pires, C; Zwick, V | 1 |
| Chattopadhyay, S; Christensen, DP; Fisher, SL; Galbo, T; Gale, JP; Gilbert, TJ; Holson, EB; Hooker, JM; Kaya, T; Leroy, M; Lundh, M; Mandrup-Poulsen, T; McCarren, P; Meier, BC; Morgan, NG; Richardson, S; Vetere, A; Wagner, BK; Wagner, FF; Walpita, D; Zhang, YL | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Chen, W; Dong, G; Miao, C; Rao, Y; Sheng, C; Wang, P; Wang, X; Xu, T; Yang, X; Zhang, W | 1 |
| Li, Y; Tang, P; Xie, R; Yuan, Q | 1 |
| Dong, G; Fang, K; He, S; Miao, Z; Sheng, C; Wang, W; Wu, S | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Agbaba, D; Bertrand, P; Blanquart, C; Bouchet, S; Fouchaq, B; Linot, C; Nikolic, K; Roche, J; Ruzic, D | 1 |
| Codd, R; Gotsbacher, MP; Roth, L | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Gridelli, C; Maione, P; Rossi, A | 1 |
| Hu, PW; Jamaluddin, MS; Jan, Y; Rice, AP; Siwak, EB | 1 |
Reviews
1 review(s) available for ci 994 and vorinostat
| Article | Year |
|---|---|
The potential role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer.
Topics: Animals; Antineoplastic Agents; Benzamides; Butyrates; Carcinoma, Non-Small-Cell Lung; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Indoles; Lung Neoplasms; Panobinostat; Phenylenediamines; Vorinostat | 2008 |
Other Studies
13 other study(ies) available for ci 994 and vorinostat
| Article | Year |
|---|---|
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Imidazoles; Male; Neoplasms, Experimental; Phenylenediamines; Prostatic Neoplasms; Pyridines; Transplantation, Heterologous; Tretinoin | 2008 |
Chemical phylogenetics of histone deacetylases.
Topics: | 2010 |
Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.
Topics: Alkenes; Benzamides; Dose-Response Relationship, Drug; Formic Acid Esters; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2016 |
An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Line; Cytoprotection; Drug Design; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Insulin-Secreting Cells; Molecular Sequence Data; Protein Isoforms; Rats | 2016 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Death; Cell Line, Tumor; Drug Discovery; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Nicotinamide Phosphoribosyltransferase; Small Molecule Libraries; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2017 |
Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Docking Simulation; Molecular Structure; ortho-Aminobenzoates; Structure-Activity Relationship; Thiocarbamates | 2018 |
Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor Agents.
Topics: A549 Cells; Acetylation; Animals; Antineoplastic Agents; Binding Sites; Drug Design; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Mice, Nude; Proto-Oncogene Proteins c-mdm2; Rats, Sprague-Dawley; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling.
Topics: | 2019 |
Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors.
Topics: Chromatography, Affinity; Coordination Complexes; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imino Acids; Metalloproteins; Metals, Heavy; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2020 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb.
Topics: Antiretroviral Therapy, Highly Active; Benzamides; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclin T; Cyclin-Dependent Kinase 9; Depsipeptides; Enzyme Activation; Gene Expression Regulation, Viral; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Hydroxamic Acids; Indoles; Panobinostat; Phenylenediamines; Phosphorylation; Positive Transcriptional Elongation Factor B; Proviruses; Virus Activation; Virus Latency; Virus Replication; Vorinostat | 2016 |