ci 988 has been researched along with sincalide in 22 studies
| Studies (ci 988) | Trials (ci 988) | Recent Studies (post-2010) (ci 988) | Studies (sincalide) | Trials (sincalide) | Recent Studies (post-2010) (sincalide) |
|---|---|---|---|---|---|
| 147 | 8 | 14 | 4,015 | 72 | 533 |
| Protein | Taxonomy | ci 988 (IC50) | sincalide (IC50) |
|---|---|---|---|
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.0006 | |
| Cholecystokinin receptor type A | Homo sapiens (human) | 0.0006 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.001 | |
| Gastrin/cholecystokinin type B receptor | Mus musculus (house mouse) | 0.0008 | |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (86.36) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horwell, DC; Hughes, J; Hunter, JC; Pritchard, MC; Richardson, RS; Roberts, E; Woodruff, GN | 1 |
| Boden, P; Costall, B; Domeney, A; Horwell, DC; Hughes, J; Hunter, JC; Kelly, E; Pinnock, RD; Woodruff, GN | 1 |
| Birkemo, LS; Croom, DK; Dezube, M; Dougherty, RW; Ervin, GN; Grizzle, MK; James, MK; Johnson, MF; Mosher, JT; Sugg, EE | 1 |
| Boden, P; Hill, DR; Hughes, J; Pinnock, R; Singh, L; Woodruff, GN | 1 |
| Horwell, DC | 1 |
| Chen, D; Ding, XQ; Håkanson, R | 1 |
| Gaw, AJ; Hills, DM; Spraggs, CF | 1 |
| Blanchard, JC; Böhme, GA; Lemaire, M; Piot, O; Roques, BP | 1 |
| Akuzawa, S; Ito, H; Kamato, T; Katuyama, Y; Kobayashi, A; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H | 1 |
| Chiba, T; DelValle, J; Park, J; Yamada, T | 1 |
| Chapman, KL; Freedman, SB; Heald, A; Patel, S; Smith, AJ | 1 |
| Ohtsuka, T; Yokose, K | 1 |
| Rakovska, A | 1 |
| Brotchi, J; Camby, I; Danguy, A; Kiss, R; Martinez, J; Pasteels, JL; Salmon, I | 1 |
| Goudreau, N; Guillaume-Rousselet, N; Jagerschmidt, A; Maigret, B; Roques, BP; Vikland, ML | 1 |
| Birkemo, LS; Ervin, GN; Johnson, MF; Mosher, JT | 1 |
| Ahmed, M; Ballinger, A; Clark, M; Kumar, P | 1 |
| Black, JW; Griffin, EP; Harper, EA; Shankley, NP | 1 |
| Black, JW; Harper, EA; Shankley, NP | 1 |
| Antonelli, T; Bebe, BW; Ferraro, L; Glennon, J; O'Connor, WT; Tanganelli, S; Tomasini, MC | 1 |
| Kamei, J; Nagase, H; Zushida, K | 1 |
| Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
2 review(s) available for ci 988 and sincalide
| Article | Year |
|---|---|
Functional role of brain CCK receptors.
Topics: Animals; Autoradiography; Benzodiazepinones; Binding Sites; Brain; Devazepide; Indoles; Meglumine; Mice; Rats; Receptors, Cholecystokinin; Sincalide | 1991 |
[Cholecystokinin receptor antagonists].
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Furans; Indoles; Meglumine; Molecular Sequence Data; Proglumide; Receptors, Cholecystokinin; Sincalide; Thiophenes | 1993 |
20 other study(ies) available for ci 988 and sincalide
| Article | Year |
|---|---|
Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Cholecystokinin; Gastrins; Indicators and Reagents; Male; Mice; Receptors, Cholecystokinin; Structure-Activity Relationship | 1991 |
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Callitrichinae; Cell Membrane; Cerebral Cortex; Cholecystokinin; Electrophysiology; Humans; Indoles; Kinetics; Meglumine; Mice; Pancreas; Rats; Receptors, Cholecystokinin; Social Behavior; Sorbitol; Ventromedial Hypothalamic Nucleus | 1990 |
Modification of receptor selectivity and functional activity in cholecystokinin peptoid ligands.
Topics: Adamantane; Amino Acid Sequence; Animals; Appetite Depressants; CHO Cells; Cricetinae; Humans; Indoles; Ligands; Magnetic Resonance Spectroscopy; Male; Meglumine; Molecular Sequence Data; Peptoids; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spectrometry, Mass, Fast Atom Bombardment; Tetragastrin; Tryptophan | 1995 |
Development of CCK-B antagonists.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blood-Brain Barrier; Cerebral Cortex; Cholecystokinin; Drug Design; Indoles; Meglumine; Mice; Molecular Sequence Data; Peptide Fragments; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship | 1991 |
Cholecystokinin-B receptor ligands of the dipeptoid series act as agonists on rat stomach histidine decarboxylase.
Topics: Animals; Benzodiazepinones; Devazepide; Enzyme Activation; Gastrins; Histidine Decarboxylase; Indoles; Ligands; Male; Meglumine; Phenethylamines; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stomach | 1995 |
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecystokinin; Decerebrate State; Devazepide; Dose-Response Relationship, Drug; Gastrins; Guanethidine; Heart Rate; Hormone Antagonists; Hormones; Hypertension; Indoles; Male; Meglumine; Pentagastrin; Phentolamine; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Tetragastrin | 1995 |
CCK-A and CCK-B selective receptor agonists and antagonists modulate olfactory recognition in male rats.
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Cognition; Indoles; Male; Meglumine; Molecular Sequence Data; Peptide Fragments; Phenylurea Compounds; Pyrazoles; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Smell; Social Behavior | 1994 |
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1994 |
Distinct receptors for cholecystokinin and gastrin on canine fundic D-cells.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Cholecystokinin; Devazepide; Dogs; Gastric Fundus; Gastric Mucosa; Gastrins; Indoles; Kinetics; Meglumine; Receptors, Cholecystokinin; Sincalide; Somatostatin | 1993 |
Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding.
Topics: Analysis of Variance; Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Guinea Pigs; Indoles; Injections, Intravenous; Injections, Intraventricular; Male; Meglumine; Mice; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Succinimides; Tetrazoles | 1994 |
Cholecystokinin-GABA interactions in rat striatum.
Topics: Animals; Calcium; Cholecystokinin; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin; Tritium | 1995 |
Influence of gastrin on human astrocytic tumor cell proliferation.
Topics: Amino Acid Sequence; Astrocytoma; Autoradiography; Benzodiazepinones; Brain Neoplasms; Cell Division; Cholecystokinin; Devazepide; Gastrins; Hormone Antagonists; Humans; Indoles; Meglumine; Molecular Sequence Data; Peptide Fragments; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Thymidine; Tritium; Tumor Cells, Cultured | 1996 |
His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity.
Topics: Animals; Arginine; Base Sequence; Benzodiazepinones; Cholecystokinin; Devazepide; Histidine; Indoles; Meglumine; Models, Molecular; Molecular Sequence Data; Phenylurea Compounds; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tetragastrin | 1996 |
Several roles of CCKA and CCKB receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning.
Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Psychological; Devazepide; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Lithium Chloride; Male; Meglumine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Taste | 1996 |
Gastrin effects on growth and exocrine secretion in the neonatal rat pancreas.
Topics: Amylases; Animals; Animals, Newborn; Female; Gastrins; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Meglumine; Pancreas; Pregnancy; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1997 |
Analysis of the behaviour of selected CCKB/gastrin receptor antagonists in radioligand binding assays performed in mouse and rat cerebral cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Guinea Pigs; Hormone Antagonists; Indoleacetic Acids; Indoles; Iodine Radioisotopes; Male; Meglumine; Mice; Pancreas; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Succinimides; Thiazoles; Tritium | 1999 |
Characterization of the binding of a novel radioligand to CCKB/gastrin receptors in membranes from rat cerebral cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Kinetics; Male; Meglumine; Membranes; Nootropic Agents; Pentagastrin; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tritium | 1999 |
Evidence for a nucleus accumbens CCK2 receptor regulation of rat ventral pallidal GABA levels: a dual probe microdialysis study.
Topics: Animals; Bicuculline; Devazepide; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin | 2000 |
Role of cholecystokinin in the reduction of endomorphin-2-induced antinociception in diabetic mice.
Topics: Analgesics; Animals; Behavior, Animal; Cholecystokinin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Meglumine; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Pain; Pain Measurement; Sincalide | 2001 |
Contribution of CCK1 receptors to cardiovascular and respiratory effects of cholecystokinin in anesthetized rats.
Topics: Administration, Intravenous; Animals; Blood Pressure; Devazepide; Heart Rate; Indoles; Male; Meglumine; Nodose Ganglion; Rats; Rats, Wistar; Receptors, Cholecystokinin; Respiration; Respiratory Rate; Sincalide; Tidal Volume; Vagotomy | 2015 |