ci 988 has been researched along with pentagastrin in 9 studies
| Studies (ci 988) | Trials (ci 988) | Recent Studies (post-2010) (ci 988) | Studies (pentagastrin) | Trials (pentagastrin) | Recent Studies (post-2010) (pentagastrin) |
|---|---|---|---|---|---|
| 147 | 8 | 14 | 3,639 | 207 | 51 |
| Protein | Taxonomy | ci 988 (IC50) | pentagastrin (IC50) |
|---|---|---|---|
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.8875 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horwell, DC; Hughes, J; Hunter, JC; Pritchard, MC; Richardson, RS; Roberts, E; Woodruff, GN | 1 |
| Field, MJ; Hughes, J; Menzies, R; Oles, RJ; Singh, L; Vass, CA; Woodruff, GN | 1 |
| Field, MJ; Hughes, J; Lewis, AS; Singh, L; Woodruff, GN | 1 |
| Gaw, AJ; Hills, DM; Spraggs, CF | 1 |
| Daum, P; Hill, DR; Pinnock, RD; Suman-Chauhan, N; Woodruff, GN | 1 |
| Akuzawa, S; Ito, H; Kamato, T; Katuyama, Y; Kobayashi, A; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H | 1 |
| Boyce, S; Rupniak, NM; Webb, JK | 1 |
| Bado, A; Blommaert, AG; Böhme, A; Ducos, B; Garbay, C; Moizo, L; Roques, BP; Weng, JH | 1 |
| Black, JW; Harper, EA; Shankley, NP | 1 |
9 other study(ies) available for ci 988 and pentagastrin
| Article | Year |
|---|---|
Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Cholecystokinin; Gastrins; Indicators and Reagents; Male; Mice; Receptors, Cholecystokinin; Structure-Activity Relationship | 1991 |
The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Carbolines; Central Nervous System Depressants; Cholecystokinin; Conflict, Psychological; Devazepide; Drug Interactions; Ethanol; Hypnotics and Sedatives; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Motor Activity; Pentagastrin; Pentobarbital; Pentylenetetrazole; Phenylurea Compounds; Postural Balance; Rats; Receptors, Cholecystokinin; Social Behavior | 1991 |
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety.
Topics: Animals; Anxiety; Benzodiazepinones; Cerebral Ventricles; Ceruletide; Chlordiazepoxide; Cholecystokinin; Devazepide; Indoles; Injections, Intraventricular; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin | 1991 |
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecystokinin; Decerebrate State; Devazepide; Dose-Response Relationship, Drug; Gastrins; Guanethidine; Heart Rate; Hormone Antagonists; Hormones; Hypertension; Indoles; Male; Meglumine; Pentagastrin; Phentolamine; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Tetragastrin | 1995 |
The cholecystokinin-induced increase in intracellular calcium in AR42J cells is mediated by CCKB receptors linked to internal calcium stores.
Topics: Animals; Benzodiazepinones; Bridged-Ring Compounds; Calcium; Cholecystokinin; Devazepide; Dipeptides; Gastric Mucosa; Guinea Pigs; Indoles; Manganese; Meglumine; Pentagastrin; Rats; Receptors, Cholecystokinin; Tumor Cells, Cultured | 1994 |
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1994 |
Inhibition of pentagastrin-induced pressor response in conscious rats by the CCK-B receptor antagonist CI-988 and chlordiazepoxide.
Topics: Animals; Blood Pressure; Carbolines; Chlordiazepoxide; Hormone Antagonists; Indoles; Male; Meglumine; Pentagastrin; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin | 1996 |
Role of N- and C-terminal substituents on the CCK-B agonist-antagonist pharmacological profile of Boc-Trp-Phg-Asp-Nal-NH2 derivatives.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Benzodiazepinones; CHO Cells; Cholecystokinin; Cricetinae; Dose-Response Relationship, Drug; Electrophysiology; Gastric Acid; Gastrointestinal Agents; Hippocampus; Indoles; Inositol Phosphates; Male; Meglumine; Molecular Sequence Data; Neurons; Neurotransmitter Agents; Oligopeptides; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Structure-Activity Relationship; Time Factors; Transfection | 1996 |
Characterization of the binding of a novel radioligand to CCKB/gastrin receptors in membranes from rat cerebral cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Kinetics; Male; Meglumine; Membranes; Nootropic Agents; Pentagastrin; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tritium | 1999 |