Page last updated: 2024-09-02

ci 988 and meglumine

ci 988 has been researched along with meglumine in 127 studies

Compound Research Comparison

Studies (ci 988)	Trials (ci 988)	Recent Studies (post-2010) (ci 988)	Studies (meglumine)	Trials (meglumine)	Recent Studies (post-2010) (meglumine)
147	8	14	4,168	413	1,399

Research

Studies (127)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	104 (81.89)	18.2507
2000's	15 (11.81)	29.6817
2010's	8 (6.30)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Branchereau, P; Champagnat, J; Denavit-Saubie, M; Roques, BP	1
Field, MJ; Hughes, J; Singh, L; Vass, CA; Woodruff, GN	1
Kearney, AS; Mehta, SC; Radebaugh, GW	1
Spealman, RD	1
Crawley, JN	1
Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E	1
Hökfelt, T; Horwell, DC; Hughes, J; Wiesenfeld-Hallin, Z; Xu, XJ	3
Drysdale, MJ; Horwell, DC; Pritchard, MC	1
Costall, B; Domeney, AM; Hughes, J; Kelly, ME; Naylor, RJ; Woodruff, GN	1
Barrett, JE; Powell, KR	1
Hughes, J; Hunter, JC; Woodruff, GN	1
Field, MJ; Hughes, J; Menzies, R; Oles, RJ; Singh, L; Vass, CA; Woodruff, GN	1
Harding, M; Hayward, NJ; Hughes, J; Lloyd, SA; McKnight, AT; Woodruff, GN	1
Campbell, BJ; Dimaline, R; Dockray, GJ; Hughes, J	1
Boden, P; Hill, DR; Hughes, J; Pinnock, R; Singh, L; Woodruff, GN	1
Horwell, DC	1
Boden, P; Costall, B; Domeney, A; Horwell, DC; Hughes, J; Hunter, JC; Kelly, E; Pinnock, RD; Woodruff, GN	1
Field, MJ; Hughes, J; Lewis, AS; Singh, L; Woodruff, GN	1
Chen, D; Ding, XQ; Håkanson, R	1
Gaw, AJ; Hills, DM; Spraggs, CF	1
Birkemo, LS; Croom, DK; Dezube, M; Dougherty, RW; Ervin, GN; Grizzle, MK; James, MK; Johnson, MF; Mosher, JT; Sugg, EE	1
Hoffmann, O; Wiesenfeld-Hallin, Z	2
Bickerdike, MJ; Dourish, CT; Fletcher, A; Marsden, CA	1
Blommaert, A; Fournié-Zaluski, MC; Noble, F; Roques, BP	1
Blommaert, AG; Ducos, B; Fournie-Zaluski, MC; Maldonado, R; Roques, BP; Valverde, O	1
Corwin, RL; Crawley, JN; Hardy, M; Jörn, A	1
Daum, P; Hill, DR; Pinnock, RD; Suman-Chauhan, N; Woodruff, GN	1
Derrien, M; Ducos, B; Durieux, C; McCort-Tranchepain, I; Roques, BP	1
Dooley, DJ; Klamt, I	1
Blanchard, JC; Böhme, GA; Lemaire, M; Piot, O; Roques, BP	1
Abelson, JL; Bammert-Adams, J; Curtis, GC; Fantone, R; Nesse, R; Pyke, RE	1
Akuzawa, S; Ito, H; Kamato, T; Katuyama, Y; Kobayashi, A; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H	1
Hökfelt, T; Hughes, J; Jing-Xia, H; Seiger, Å; Wiesenfeld-Hallin, Z; Xiao-Jun, X	1
Black, JW; Shankley, NP; Welsh, NJ	1
Dickinson, CJ; Seva, C; Yamada, T	1
Massey, BW; Vanover, KE; Woolverton, WL	1
Fournie-Zaluski, MC; Maldonado, R; Roques, BP; Valverde, O	2
Higginbottom, M; Hill, DR; Horwell, DC; Mostafai, E; Roberts, E; Suman-Chauhan, N	1
Chiba, T; DelValle, J; Park, J; Yamada, T	1
Campbell, BJ; Dimaline, R; Dockray, GJ; Garner, A; Hughes, J	1
Blackmore, M; Doherty, E; Hirst, BH; Manning, JE	1
Dickenson, A; Stanfa, L; Wiesenfeld-Hallin, Z; Xu, XJ	1
Blommaert, A; Derrien, M; Durieux, C; Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Valverde, O	1
Chapman, KL; Freedman, SB; Heald, A; Patel, S; Smith, AJ	2
Hökfelt, T; Hughes, J; Wiesenfeld-Hallin, Z; Xu, XJ	1
Ohtsuka, T; Yokose, K	1
Boyle, SJ; McKnight, AT; Tang, KW; Woodruff, GN	1
Christoffersen, CL; Meltzer, LT; Razmpour, A; Serpa, KA	1
Dimaline, R; Dockray, GJ; Evans, D; Forster, ER; Sandvik, AK	1
Hökfelt, T; Hughes, J; Puke, MJ; Verge, VM; Wiesenfeld-Hallin, Z; Xu, XJ	1
Blommaert, AG; Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Valverde, O	1
Hinks, GL; Hughes, J; Poat, JA	1
Bradwejn, J; Hinton, J; Koszycki, D; Paradis, M; Reece, P; Sedman, A	1
Rakovska, A	1
Brotchi, J; Camby, I; Danguy, A; Kiss, R; Martinez, J; Pasteels, JL; Salmon, I	1
Howes, LG; Morris, DL; Romani, R	2
Boyce, S; Rupniak, NM; Webb, JK	1
Goudreau, N; Guillaume-Rousselet, N; Jagerschmidt, A; Maigret, B; Roques, BP; Vikland, ML	1
Bado, A; Blommaert, AG; Böhme, A; Ducos, B; Garbay, C; Moizo, L; Roques, BP; Weng, JH	1
Birkemo, LS; Ervin, GN; Johnson, MF; Mosher, JT	1
Adams, JB; Costa, J; Cutler, NR; Greiner, M; Pande, AC; Pierce, MW; Pyke, RE; Schweizer, E; Wilcox, CS; Wisselink, PG	1
Champagnat, J; Denavit-Saubie, M; McLean, HA	1
Araldi, G; Donati, D; Natalini, B; Oliosi, B; Pellicciari, R; Tarzia, G; Ursini, A; van Amsterdam, F	1
Bjorge, SM; Hinton, JP; Hoffman, K; Jennings, K; Pablo, JC; Wright, DS	1
Atwal, P; Field, MJ; Hunter, JC; Oles, RJ; Singh, L; Woodruff, GN	1
Horwell, D; Pritchard, M; Raphy, J; Ratcliffe, G	1
Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Ruiz, F	1
Dockray, GJ; Forster, E; Garcia, L; Hill, D; Horwell, DC; Hughes, J; Pritchard, MC; Toescu, E; Woodruff, G	1
Adams, JB; Cook, J; Cowley, DS; Pyke, RE; Roy-Byrne, PP; Wingerson, D; Zaccharias, P	1
Brown, P; Field, M; Hinks, GL; Hughes, J; Poat, JA	1
Augelli-Szafran, CE; Hill, D; Horwell, DC; Kneen, C; Ortwine, DF; Pritchard, MC; Purchase, TS; Roth, BD; Suman-Chauhan, N; Trivedi, BK; Webdale, L	1
Durieux, C; Léna, I; Roques, BP	1
Jenck, F; Martin, JR; Moreau, JL	1
den Boer, JA; Pande, AC; Slaap, B; van Es-Radhakishun, F; van Megen, HJ; Westenberg, HG	1
Ahmed, M; Ballinger, A; Clark, M; Kumar, P	1
Besson, JM; Buritova, J; Fournié-Zaluski, MC; Honore, P; Roques, BP	1
Endo, T; Nagasaki, M; Noto, T	1
Maldonado, R; Roques, BP; Smadja, C; Valverde, O	1
Marvik, R; Sandvik, AK; Waldum, HL	1
Elfvin, A; Fournié-Zaluski, MC; Hao, JX; Roques, BP; Wiesenfeld-Hallin, Z; Xu, XJ	1
Coric, P; Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Ruiz, F; Smadja, C	1
Costall, B; Naylor, RJ	1
Bestervelt, LL; Dethloff, LA; Patmore, SJ; Tierney, BM; Zandee, JC	1
Lucas, GA; Wiesenfeld-Hallin, Z; Xu, XJ	1
Roques, BP; Valverde, O	1
Little, HJ; Wilson, J	1
Alster, P; Brodin, E; de Araújo Lucas, G; Gustafsson, H; Schött, E; Stiller, CO; Wiesenfeld-Hallin, Z	1
Little, HJ; Watson, WP; Wilson, J	1
Alchepo, B; Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L	1
Hinton, JP; Trivedi, BK	1
Aldskogius, H; Grant, G; Hao, JX; Hökfelt, T; Wiesenfeld-Hallin, Z; Xu, XJ	1
de Tullio, P; Delarge, J; Pirotte, B	1
Black, JW; Griffin, EP; Harper, EA; Shankley, NP	1
Black, JW; Harper, EA; Shankley, NP	1
Charney, DS; Goddard, AW; Goodman, WK; Heninger, GR; Money, R; Pande, AC; Price, LH; Woods, SW	1
Dickinson, CJ; Sawada, M; Stepan, VM; Todisco, A	1
Akil, H; Day, HE	1
Adams, JB; Greiner, M; Lydiard, RB; Pande, AC; Pierce, MW	1
Broberger, C; Farkas-Szallasi, T; Hökfelt, T; Lundberg, JM; Szallasi, A; Wiesenfeld-Hallin, Z; Xu, XJ	1
Barr, B; Bestervelt, L; Dethloff, L	1
Pache, DM; Sewell, RD; Subhan, F	1
Ardid, D; Boucher, M; Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Méen, M	1
Bradley, EL; Bright, CA; Kissin, I	1
Fournié-Zaluski, M; Hutcheson, DM; Maldonado, R; Pache, DM; Roques, BP; Sewell, RD; Subhan, F	1
Boucher, M; Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J	1
Kamei, J; Zushida, K	1
Antonelli, T; Bebe, BW; Ferraro, L; Glennon, J; O'Connor, WT; Tanganelli, S; Tomasini, MC	1
Kamei, J; Nagase, H; Zushida, K	1
Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Fournié-Zaluski, MC; Méen, M; Roques, BP	1
Jensen, RT; Moody, TW	1
Lawrence, AJ; Lodge, DJ	1
Canestrelli, C; Chen, H; Cupo, A; Fournié-Zaluski, MC; Le Guen, S; Maldonado, R; Mas Nieto, M; Noble, F; Roques, BP	1
Cho, HY; Hong, SK; Kim, J; Kim, JH; Kim, Y; Yoon, YW	1
Becker, C; Benoliel, JJ; Blugeot, A; Mauborgne, A; Pohl, M; Rivat, C; Zeau, B	1
Benturquia, N; Canestrelli, C; Crete, D; Mas Nieto, M; Noble, F; Roques, BP; Wilson, J	1
Akiyama, M; Goto, Y; Inagaki, M; Izumi, H; Kaga, M; Li, H; Matsuda, Y; Matsushima, Y; Ohta, H; Seki, M; Toda, T	1
Frommelt, L; Goebel-Stengel, M; Hofmann, T; Klapp, BF; Kobelt, P; Lembke, V; Mönnikes, H; Stengel, A; Wiedenmann, B	1
Asico, LD; Chen, Y; He, D; Jose, PA; Villar, VA; Zeng, C; Zheng, S; Zhou, L	1
Bagot, RC; Berton, O; Cahill, ME; Dietz, DM; Fallon, B; Feng, J; Ferguson, D; Harrigan, E; Joshi, T; Ku, SM; Mazei-Robison, M; Nestler, EJ; Robison, AJ; Vialou, V; Winstanley, CA	1
Jensen, RT; Moody, TW; Moreno, P; Nuche-Berenguer, B	1
Kaczyńska, K; Szereda-Przestaszewska, M	1

Reviews

7 review(s) available for ci 988 and meglumine

Article	Year
Neurochemical actions of CCK underlying the therapeutic potential of CCK-B antagonists. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Cholecystokinin; gamma-Aminobutyric Acid; Indoles; Meglumine; Receptors, Cholecystokinin; Spinal Cord; Substance-Related Disorders	1991
Functional role of brain CCK receptors. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Autoradiography; Benzodiazepinones; Binding Sites; Brain; Devazepide; Indoles; Meglumine; Mice; Rats; Receptors, Cholecystokinin; Sincalide	1991
Cholecystokinin and morphine analgesia: variations on a theme. Trends in pharmacological sciences, 1994, Volume: 15, Issue:3 Topics: Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Humans; Indoles; Meglumine; Morphine; Phenylurea Compounds; Receptors, Cholecystokinin	1994
[Cholecystokinin receptor antagonists]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1993, Volume: 38, Issue:11 Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Furans; Indoles; Meglumine; Molecular Sequence Data; Proglumide; Receptors, Cholecystokinin; Sincalide; Thiophenes	1993
'Targeted' molecular diversity: design and development of non-peptide antagonists for cholecystokinin and tachykinin receptors. Immunopharmacology, 1996, Volume: 33, Issue:1-3 Topics: Amino Acid Sequence; Animals; Drug Design; Drug Evaluation, Preclinical; Hormone Antagonists; Humans; Indoles; Ligands; Meglumine; Molecular Structure; Oligopeptides; Peptide Library; Phenylalanine; Receptors, Cholecystokinin; Receptors, Tachykinin; Tryptophan	1996
CI-1015. An orally active CCK-B receptor antagonist with an improved pharmacokinetic profile. Pharmaceutical biotechnology, 1998, Volume: 11 Topics: Adamantane; Administration, Oral; Animals; Brain; Humans; Indoles; Meglumine; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Structure-Activity Relationship; Tryptophan	1998
Recent advances in the chemistry of cholecystokinin receptor ligands (agonists and antagonists). Current medicinal chemistry, 1999, Volume: 6, Issue:6 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Humans; Indoles; Keto Acids; Ligands; Meglumine; Peptoids; Proglumide; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spiro Compounds; Structure-Activity Relationship; Tetragastrin	1999

Trials

7 trial(s) available for ci 988 and meglumine

Article	Year
The effects of central cholecystokinin receptor blockade on hypothalamic-pituitary-adrenal and symptomatic responses to overnight withdrawal from alprazolam. Biological psychiatry, 1995, Jan-01, Volume: 37, Issue:1 Topics: Adult; Alprazolam; Cross-Over Studies; Double-Blind Method; Humans; Hypothalamo-Hypophyseal System; Indoles; Meglumine; Middle Aged; Pituitary-Adrenal System; Receptors, Cholecystokinin; Substance Withdrawal Syndrome	1995
Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers. Biological psychiatry, 1995, Dec-01, Volume: 38, Issue:11 Topics: Adult; Amino Acid Sequence; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method; Hemodynamics; Humans; Indoles; Male; Meglumine; Middle Aged; Molecular Sequence Data; Panic; Psychiatric Status Rating Scales; Receptors, Cholecystokinin; Tetragastrin	1995
A double-blind, placebo-controlled study of a CCK-B receptor antagonist, CI-988, in patients with generalized anxiety disorder. Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:6 Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Colonic Diseases, Functional; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Indoles; Male; Meglumine; Panic Disorder; Personality Inventory; Phobic Disorders; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Somatoform Disorders; Treatment Outcome	1995
Effect of CI-988, a cholecystokinin-B receptor antagonist, on lactate-induced panic. Biological psychiatry, 1996, Sep-15, Volume: 40, Issue:6 Topics: Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Heart Rate; Humans; Indoles; Lactic Acid; Male; Meglumine; Panic Disorder; Psychiatric Status Rating Scales; Receptors, Cholecystokinin	1996
The cholecystokinin-B receptor antagonist CI-988 failed to affect CCK-4 induced symptoms in panic disorder patients. Psychopharmacology, 1997, Volume: 129, Issue:3 Topics: Adolescent; Adult; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrocortisone; Indoles; Male; Meglumine; Middle Aged; Panic Disorder; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tetragastrin; Treatment Outcome	1997
Effects of the CCK(B) antagonist CI-988 on responses to mCPP in generalized anxiety disorder. Psychiatry research, 1999, Mar-22, Volume: 85, Issue:3 Topics: Adult; Affect; Analysis of Variance; Anti-Anxiety Agents; Anxiety Disorders; Blood Pressure; Female; Heart Rate; Human Growth Hormone; Humans; Hydrocortisone; Indoles; Male; Meglumine; Middle Aged; Piperazines; Prolactin; Psychiatric Status Rating Scales; Serotonin Receptor Agonists	1999
Placebo-controlled trial of the CCK-B antagonist, CI-988, in panic disorder. Biological psychiatry, 1999, Sep-15, Volume: 46, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Indoles; Meglumine; Middle Aged; Panic Disorder; Receptors, Cholecystokinin	1999

Other Studies

113 other study(ies) available for ci 988 and meglumine

Article	Year
CCK modulates inhibitory synaptic transmission in the solitary complex through CCKB sites. Neuroreport, 1992, Volume: 3, Issue:10 Topics: Animals; Benzodiazepinones; Bicuculline; Brain Stem; Cholecystokinin; Devazepide; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Indoles; Interneurons; Medulla Oblongata; Meglumine; Membrane Potentials; Microelectrodes; Phenylurea Compounds; Rats; Receptors, Cholecystokinin; Synapses; Synaptic Transmission; Vagus Nerve	1992
The antagonism of benzodiazepine withdrawal effects by the selective cholecystokininB receptor antagonist CI-988. British journal of pharmacology, 1992, Volume: 105, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Drug Administration Schedule; Indoles; Light; Male; Meglumine; Mice; Mice, Inbred Strains; Receptors, Cholecystokinin; Substance Withdrawal Syndrome	1992
Aqueous stability and solubility of CI-988, a novel "dipeptoid" cholecystokinin-B receptor antagonist. Pharmaceutical research, 1992, Volume: 9, Issue:8 Topics: Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Hydrolysis; Indoles; Meglumine; Receptors, Cholecystokinin; Solubility	1992
Failure of cholecystokinin antagonists to modify the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2 Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Devazepide; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Receptors, Cholecystokinin; Reinforcement Schedule; Saimiri	1992
Subtype-selective cholecystokinin receptor antagonists block cholecystokinin modulation of dopamine-mediated behaviors in the rat mesolimbic pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:9 Topics: Animals; Behavior, Animal; Benzodiazepinones; Cholecystokinin; Darkness; Devazepide; Dopamine; Indoles; Injections, Intraperitoneal; Limbic System; Male; Meglumine; Microinjections; Motor Activity; Nucleus Accumbens; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Tegmentum Mesencephali	1992
Amide bond replacements incorporated into CCK-B selective "dipeptoids". Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8 Topics: Amides; Cholecystokinin; Indoles; Meglumine; Models, Molecular; Receptors, Cholecystokinin; Structure-Activity Relationship	1992
CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the rat. British journal of pharmacology, 1992, Volume: 105, Issue:3 Topics: Animals; Behavior, Animal; Drug Tolerance; Indoles; Injections, Intraperitoneal; Male; Meglumine; Morphine; Morphine Dependence; Naloxone; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Substance Withdrawal Syndrome	1992
Rationally designed "dipeptoid" analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Carboxylic Acids; Cholecystokinin; Dipeptides; Drug Design; Indoles; Male; Meglumine; Mice; Rats; Receptors, Cholecystokinin	1992
Anxiolytic effects of CCK-B antagonists. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Callitrichinae; Diazepam; Indoles; Meglumine; Mice; Rats; Receptors, Cholecystokinin; Substance Withdrawal Syndrome	1991
Evaluation of the effects of PD 134308 (CI-988), a CCK-B antagonist, on the punished responding of squirrel monkeys. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Chlordiazepoxide; Electroshock; Indoles; Male; Meglumine; Punishment; Receptors, Cholecystokinin; Saimiri	1991
The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist. British journal of pharmacology, 1991, Volume: 104, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Carbolines; Central Nervous System Depressants; Cholecystokinin; Conflict, Psychological; Devazepide; Drug Interactions; Ethanol; Hypnotics and Sedatives; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Motor Activity; Pentagastrin; Pentobarbital; Pentylenetetrazole; Phenylurea Compounds; Postural Balance; Rats; Receptors, Cholecystokinin; Social Behavior	1991
The effect of CCKB/gastrin antagonists on stimulated gastric acid secretion in the anaesthetized rat. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Animals; Anti-Anxiety Agents; Atropine; Benzodiazepinones; Bethanechol Compounds; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastrins; Histamine; Indoles; Male; Meglumine; Omeprazole; Phenylurea Compounds; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin	1991
PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:18 Topics: Analgesics; Animals; Cholecystokinin; Drug Synergism; Female; Galanin; Indoles; Injections, Spinal; Kinetics; Male; Meglumine; Morphine; Naloxone; Nociceptors; Pain; Peptides; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Reflex; Sorbitol; Spinal Cord; Time Factors	1990
Studies on the effect of systemic PD134308 (CAM 958) in spinal reflex and pain models with special reference to interaction with morphine and intrathecal galanin. Neuropeptides, 1991, Volume: 19 Suppl Topics: Analgesics; Animals; Drug Interactions; Female; Galanin; Indoles; Injections, Intravenous; Injections, Spinal; Male; Meglumine; Morphine; Naloxone; Pain; Peptides; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Reflex; Spinal Cord	1991
Inhibition of food intake by omeprazole in the chicken. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: Animals; Animals, Newborn; Body Weight; Chickens; Depression, Chemical; Eating; Gastrins; Indoles; Meglumine; Omeprazole; Radioimmunoassay; Receptors, Cholecystokinin; Satiety Response	1991
Development of CCK-B antagonists. Neuropeptides, 1991, Volume: 19 Suppl Topics: Amino Acid Sequence; Animals; Binding Sites; Blood-Brain Barrier; Cerebral Cortex; Cholecystokinin; Drug Design; Indoles; Meglumine; Mice; Molecular Sequence Data; Peptide Fragments; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship	1991
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:17 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Callitrichinae; Cell Membrane; Cerebral Cortex; Cholecystokinin; Electrophysiology; Humans; Indoles; Kinetics; Meglumine; Mice; Pancreas; Rats; Receptors, Cholecystokinin; Social Behavior; Sorbitol; Ventromedial Hypothalamic Nucleus	1990
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety. Proceedings of the National Academy of Sciences of the United States of America, 1991, Feb-15, Volume: 88, Issue:4 Topics: Animals; Anxiety; Benzodiazepinones; Cerebral Ventricles; Ceruletide; Chlordiazepoxide; Cholecystokinin; Devazepide; Indoles; Injections, Intraventricular; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin	1991
Cholecystokinin-B receptor ligands of the dipeptoid series act as agonists on rat stomach histidine decarboxylase. Gastroenterology, 1995, Volume: 109, Issue:4 Topics: Animals; Benzodiazepinones; Devazepide; Enzyme Activation; Gastrins; Histidine Decarboxylase; Indoles; Ligands; Male; Meglumine; Phenethylamines; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stomach	1995
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat. British journal of pharmacology, 1995, Volume: 115, Issue:4 Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecystokinin; Decerebrate State; Devazepide; Dose-Response Relationship, Drug; Gastrins; Guanethidine; Heart Rate; Hormone Antagonists; Hormones; Hypertension; Indoles; Male; Meglumine; Pentagastrin; Phentolamine; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Tetragastrin	1995
Modification of receptor selectivity and functional activity in cholecystokinin peptoid ligands. Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17 Topics: Adamantane; Amino Acid Sequence; Animals; Appetite Depressants; CHO Cells; Cricetinae; Humans; Indoles; Ligands; Magnetic Resonance Spectroscopy; Male; Meglumine; Molecular Sequence Data; Peptoids; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spectrometry, Mass, Fast Atom Bombardment; Tetragastrin; Tryptophan	1995
The CCK-B receptor antagonist Cl 988 reverses tolerance to morphine in rats. Neuroreport, 1994, Dec-20, Volume: 5, Issue:18 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Indoles; Male; Meglumine; Morphine; Nociceptors; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Cholecystokinin; Time Factors	1994
The influence of 5-hydroxytryptamine re-uptake blockade on CCK receptor antagonist effects in the rat elevated zero-maze. European journal of pharmacology, 1994, Dec-27, Volume: 271, Issue:2-3 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Devazepide; Diazepam; Indoles; Male; Maze Learning; Meglumine; Niacinamide; Phenylurea Compounds; Piperazines; Piperidines; Rats; Receptors, Cholecystokinin; Selective Serotonin Reuptake Inhibitors; Zimeldine	1994
A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test. European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2 Topics: Analgesics; Animals; Disulfides; Enkephalins; Formaldehyde; Indoles; Male; Meglumine; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Phenylalanine; Receptors, Cholecystokinin; Receptors, Opioid, delta; Receptors, Opioid, mu	1995
Inhibition of morphine withdrawal by the association of RB 101, an inhibitor of enkephalin catabolism, and the CCKB antagonist PD-134,308. British journal of pharmacology, 1995, Volume: 114, Issue:5 Topics: Analgesics; Animals; Behavior, Animal; Binding, Competitive; Body Temperature; Diprenorphine; Disulfides; Drug Combinations; Drug Synergism; Enkephalins; Indoles; Male; Meglumine; Mice; Morphine; Motor Activity; Naloxone; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Substance Withdrawal Syndrome; Weight Loss	1995
The CCK-B antagonist CI-988 increases dopamine levels in microdialysate from the rat nucleus accumbens via a tetrodotoxin- and calcium-independent mechanism. Journal of neurochemistry, 1995, Volume: 65, Issue:1 Topics: Animals; Calcium; Cholecystokinin; Dopamine; Dopamine Antagonists; Indoles; Male; Meglumine; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tetrodotoxin	1995
The cholecystokinin-induced increase in intracellular calcium in AR42J cells is mediated by CCKB receptors linked to internal calcium stores. Neuropeptides, 1994, Volume: 27, Issue:3 Topics: Animals; Benzodiazepinones; Bridged-Ring Compounds; Calcium; Cholecystokinin; Devazepide; Dipeptides; Gastric Mucosa; Guinea Pigs; Indoles; Manganese; Meglumine; Pentagastrin; Rats; Receptors, Cholecystokinin; Tumor Cells, Cultured	1994
Heterogeneity of CCK-B receptors involved in animal models of anxiety. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:1 Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Benzodiazepinones; Cholecystokinin; Devazepide; Guinea Pigs; In Vitro Techniques; Indoles; Male; Meglumine; Mice; Molecular Sequence Data; Pancreas; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cholecystokinin	1994
Differential profile of the CCKB receptor antagonist CI-988 and diazepam in the four-plate test. Psychopharmacology, 1993, Volume: 112, Issue:4 Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Electroshock; Exploratory Behavior; Flumazenil; Indoles; Male; Meglumine; Mice; Ondansetron; Receptors, Cholecystokinin	1993
CCK-A and CCK-B selective receptor agonists and antagonists modulate olfactory recognition in male rats. Psychopharmacology, 1994, Volume: 115, Issue:4 Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Cognition; Indoles; Male; Meglumine; Molecular Sequence Data; Peptide Fragments; Phenylurea Compounds; Pyrazoles; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Smell; Social Behavior	1994
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2 Topics: Animals; Benzodiazepines; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide	1994
Chronic pain-related behaviors in spinally injured rats: evidence for functional alterations of the endogenous cholecystokinin and opioid systems. Pain, 1994, Volume: 56, Issue:3 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Cholecystokinin; Chronic Disease; Diazepam; Endorphins; Female; Indoles; Meglumine; Naloxone; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Spinal Cord Injuries; Vocalization, Animal	1994
Comparative analysis of the vagal stimulation of gastric acid secretion in rodent isolated stomach preparations. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Animals; Atropine; Cholecystokinin; Cholinergic Antagonists; Electric Stimulation; Gastric Acid; Gastric Mucosa; Guinea Pigs; Hexamethonium Compounds; Histamine H2 Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Male; Meglumine; Mice; Rats; Rats, Wistar; Receptors, Cholecystokinin; Species Specificity; Tetrodotoxin; Vagus Nerve	1994
Growth-promoting effects of glycine-extended progastrin. Science (New York, N.Y.), 1994, Jul-15, Volume: 265, Issue:5170 Topics: Benzodiazepinones; Binding Sites; Cell Division; Gastrins; Humans; Indoles; Meglumine; Octreotide; Ornithine Decarboxylase; Phenylurea Compounds; Receptors, Cholecystokinin; Tumor Cells, Cultured	1994
Effects of cholecystokinin antagonists on the discriminative stimulus effects of cocaine in rats and monkeys. Drug and alcohol dependence, 1994, Volume: 34, Issue:2 Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Devazepide; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Female; Indoles; Macaca mulatta; Male; Meglumine; Mesencephalon; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Receptors, Dopamine; Substance-Related Disorders; Synaptic Transmission	1994
Cholecystokinin B antagonists strongly potentiate antinociception mediated by endogenous enkephalins. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1 Topics: Adamantane; Analgesics; Animals; Benzodiazepinones; Dipeptides; Disulfides; Drug Synergism; Enkephalins; Indoles; Male; Meglumine; Nociceptors; Pain Measurement; Phenylalanine; Phenylurea Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Regression Analysis; Tail	1994
Conformationally restricted analogues of the potent CCK-B antagonist CI-988. Bioorganic & medicinal chemistry, 1993, Volume: 1, Issue:3 Topics: Animals; Binding Sites; Cerebral Cortex; In Vitro Techniques; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Meglumine; Mice; Molecular Conformation; Molecular Structure; Pancreas; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship	1993
Distinct receptors for cholecystokinin and gastrin on canine fundic D-cells. The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1 Topics: Animals; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Cholecystokinin; Devazepide; Dogs; Gastric Fundus; Gastric Mucosa; Gastrins; Indoles; Kinetics; Meglumine; Receptors, Cholecystokinin; Sincalide; Somatostatin	1993
The mechanism of action of gastrin releasing peptide (GRP) in stimulating avian gastric acid secretion. Regulatory peptides, 1994, Jan-13, Volume: 49, Issue:3 Topics: Analysis of Variance; Animals; Bombesin; Chickens; Dose-Response Relationship, Drug; Gastric Acid; Gastrin-Releasing Peptide; Gastrins; Indoles; Male; Meglumine; Oligopeptides; Peptides; Receptors, Cholecystokinin; Turkeys	1994
Autocrine growth stimulation of human renal Wilms' tumour G401 cells by a gastrin-like peptide. International journal of cancer, 1994, May-01, Volume: 57, Issue:3 Topics: Benzamides; Benzodiazepinones; Cell Division; Devazepide; Gastrins; Humans; Indoles; Kidney Neoplasms; Meglumine; Phenylurea Compounds; Proglumide; Receptors, Cholecystokinin; Tumor Cells, Cultured; Wilms Tumor	1994
CCK-B antagonists exhibit antidepressant-like effects and potentiate endogenous enkephalin analgesia. Correlation with in vivo binding affinities and brain penetration. Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713 Topics: Animals; Antidepressive Agents; Benzodiazepinones; Blood-Brain Barrier; Brain; Cerebral Ventricles; Cholecystokinin; Electroshock; Indoles; Injections, Intraventricular; Meglumine; Mice; Motor Activity; Peptide Fragments; Phenylurea Compounds; Receptors, Cholecystokinin	1994
Use of ex vivo binding to estimate brain penetration and central activity of CCK-B antagonists. Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713 Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Cerebral Ventricles; Indoles; Injections, Intraventricular; Inulin; Iodine Radioisotopes; Male; Meglumine; Mice; Mice, Inbred Strains; Phenylurea Compounds; Radioligand Assay; Receptors, Cholecystokinin; Tetrazoles	1994
The CCK-B antagonist CI988 enhances the reflex-depressive effect of morphine in axotomized rats. Neuroreport, 1994, Feb-24, Volume: 5, Issue:6 Topics: Animals; Axons; Depression, Chemical; Drug Synergism; Electromyography; Female; Indoles; Meglumine; Morphine; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reflex; Sciatic Nerve	1994
Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding. European journal of pharmacology, 1994, Mar-03, Volume: 253, Issue:3 Topics: Analysis of Variance; Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Guinea Pigs; Indoles; Injections, Intravenous; Injections, Intraventricular; Male; Meglumine; Mice; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Succinimides; Tetrazoles	1994
Characterization of CCK receptors in a novel smooth muscle preparation from the guinea-pig stomach by use of the selective antagonists CI-988, L-365,260 and devazepide. British journal of pharmacology, 1993, Volume: 109, Issue:4 Topics: Animals; Benzodiazepinones; Carbachol; Cholecystokinin; Devazepide; Gastric Mucosa; Gastrins; Guinea Pigs; In Vitro Techniques; Indoles; Male; Meglumine; Muscle Contraction; Muscle, Smooth; Phenylurea Compounds; Receptors, Cholecystokinin; Stomach	1993
Comparison of the effects of the cholecystokinin-B receptor antagonist, PD 134308, and the cholecystokinin-A receptor antagonist, L-364,718, on dopamine neuronal activity in the substantia nigra and ventral tegmental area. Synapse (New York, N.Y.), 1993, Volume: 13, Issue:2 Topics: Animals; Apomorphine; Benzodiazepinones; Cholecystokinin; Devazepide; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Indoles; Male; Meglumine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Substantia Nigra; Tegmentum Mesencephali	1993
Control of gastric corpus chromogranin A messenger RNA abundance in the rat. The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1 Topics: Animals; Base Sequence; Blotting, Northern; Chromogranin A; Chromogranins; Fasting; Female; Gastric Mucosa; Gastrins; Indoles; Meglumine; Molecular Sequence Data; Omeprazole; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger; Stomach	1993
Up-regulation of cholecystokinin in primary sensory neurons is associated with morphine insensitivity in experimental neuropathic pain in the rat. Neuroscience letters, 1993, Apr-02, Volume: 152, Issue:1-2 Topics: Animals; Cholecystokinin; Ganglia, Spinal; Indoles; Male; Meglumine; Morphine; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; Sciatic Nerve; Self Mutilation	1993
Weak tolerance to the antinociceptive effect induced by the association of a peptidase inhibitor and a CCKB receptor antagonist. European journal of pharmacology, 1995, Nov-03, Volume: 286, Issue:1 Topics: Analgesics; Animals; Benzodiazepinones; Disulfides; Drug Synergism; Drug Tolerance; Indoles; Male; Meglumine; Mice; Pain Measurement; Phenylalanine; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors	1995
Changes in hypothalamic cholecystokininA and cholecystokininB receptor subtypes and associated neuropeptide expression in response to salt-stress in the rat and mouse. Neuroscience, 1995, Volume: 68, Issue:3 Topics: Animals; Autoradiography; Benzodiazepinones; Cholecystokinin; Devazepide; Hormone Antagonists; Hypothalamus; In Situ Hybridization; Indoles; Male; Meglumine; Mice; Mice, Inbred Strains; Neuronal Plasticity; Neuropeptides; Oligonucleotide Probes; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger; Saline Solution, Hypertonic; Succinimides	1995
Cholecystokinin-GABA interactions in rat striatum. Neuropeptides, 1995, Volume: 29, Issue:5 Topics: Animals; Calcium; Cholecystokinin; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin; Tritium	1995
Influence of gastrin on human astrocytic tumor cell proliferation. Journal of the National Cancer Institute, 1996, May-01, Volume: 88, Issue:9 Topics: Amino Acid Sequence; Astrocytoma; Autoradiography; Benzodiazepinones; Brain Neoplasms; Cell Division; Cholecystokinin; Devazepide; Gastrins; Hormone Antagonists; Humans; Indoles; Meglumine; Molecular Sequence Data; Peptide Fragments; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Thymidine; Tritium; Tumor Cells, Cultured	1996
Gastrin receptor antagonist CI-988 inhibits growth of human colon cancer in vivo and in vitro. The Australian and New Zealand journal of surgery, 1996, Volume: 66, Issue:4 Topics: Administration, Oral; Analysis of Variance; Animals; Cell Division; Colorectal Neoplasms; Drug Evaluation, Preclinical; Hormone Antagonists; Humans; Indoles; Male; Meglumine; Mice; Mice, Nude; Neoplasms, Experimental; Receptors, Cholecystokinin; Tumor Cells, Cultured	1996
Inhibition of pentagastrin-induced pressor response in conscious rats by the CCK-B receptor antagonist CI-988 and chlordiazepoxide. Regulatory peptides, 1996, Jan-16, Volume: 61, Issue:1 Topics: Animals; Blood Pressure; Carbolines; Chlordiazepoxide; Hormone Antagonists; Indoles; Male; Meglumine; Pentagastrin; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin	1996
Dose dependent in vivo inhibition of human colorectal cancer (LoVo) by the gastrin receptor antagonist, CI-988. Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:5 Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Division; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Indoles; Male; Meglumine; Mice; Mice, Nude; Neoplasm Transplantation; Receptors, Cholecystokinin; Tumor Cells, Cultured	1996
His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity. European journal of pharmacology, 1996, Jan-18, Volume: 296, Issue:1 Topics: Animals; Arginine; Base Sequence; Benzodiazepinones; Cholecystokinin; Devazepide; Histidine; Indoles; Meglumine; Models, Molecular; Molecular Sequence Data; Phenylurea Compounds; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tetragastrin	1996
Dextromethorphan potentiates morphine antinociception, but does not reverse tolerance in rats. Neuroreport, 1996, Feb-29, Volume: 7, Issue:3 Topics: Analgesics, Opioid; Animals; Antitussive Agents; Dextromethorphan; Drug Synergism; Drug Tolerance; Hormone Antagonists; Indoles; Male; Meglumine; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley	1996
Role of N- and C-terminal substituents on the CCK-B agonist-antagonist pharmacological profile of Boc-Trp-Phg-Asp-Nal-NH2 derivatives. Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:4 Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Benzodiazepinones; CHO Cells; Cholecystokinin; Cricetinae; Dose-Response Relationship, Drug; Electrophysiology; Gastric Acid; Gastrointestinal Agents; Hippocampus; Indoles; Inositol Phosphates; Male; Meglumine; Molecular Sequence Data; Neurons; Neurotransmitter Agents; Oligopeptides; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Structure-Activity Relationship; Time Factors; Transfection	1996
Several roles of CCKA and CCKB receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning. Peptides, 1996, Volume: 17, Issue:3 Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Psychological; Devazepide; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Lithium Chloride; Male; Meglumine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Taste	1996
The CCKB antagonist PD-134,308 facilitates rewarding effects of endogenous enkephalins but does not induce place preference in rats. Psychopharmacology, 1996, Volume: 123, Issue:2 Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Enkephalins; Hormone Antagonists; Indoles; Male; Meglumine; Morphine; Pain Measurement; Rats; Rats, Wistar; Receptors, Cholecystokinin	1996
A cholecystokinin-B receptor antagonist potentiates GABAergic and glycinergic inhibition in the nucleus of the solitary tract of the rat. The European journal of neuroscience, 1996, Volume: 8, Issue:6 Topics: Animals; Anti-Anxiety Agents; Chloride Channel Agonists; Drug Synergism; Electric Conductivity; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Meglumine; Neural Inhibition; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Solitary Nucleus; Tetrodotoxin	1996
Synthesis and receptor binding affinity of cholecystokinin receptor ligands: 2-and 1-indolyl derivatives of PD134308. Farmaco (Societa chimica italiana : 1989), 1996, Volume: 51, Issue:7 Topics: Animals; Binding, Competitive; Brain Chemistry; Guinea Pigs; Hormone Antagonists; Hydrolysis; In Vitro Techniques; Indoles; Ligands; Male; Meglumine; Receptors, Cholecystokinin; Spectrophotometry, Infrared	1996
Three complementary liquid chromatographic methods for determination of the peptoid cholecystokinin-B antagonist, CI-988, in rat plasma. Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:7 Topics: Animals; Anions; Cholecystokinin; Chromatography, High Pressure Liquid; Hormone Antagonists; Indoles; Mass Spectrometry; Meglumine; Peptoids; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence	1996
Effect of CCK receptor antagonists on the antinociceptive, reinforcing and gut motility properties of morphine. British journal of pharmacology, 1996, Volume: 118, Issue:5 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hormone Antagonists; Indoles; Male; Meglumine; Morphine; Pain Threshold; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cholecystokinin	1996
Similar decrease in spontaneous morphine abstinence by methadone and RB 101, an inhibitor of enkephalin catabolism. British journal of pharmacology, 1996, Volume: 119, Issue:1 Topics: Analgesics; Animals; Disulfides; Drug Combinations; Enkephalins; Indoles; Male; Meglumine; Methadone; Morphine; Naloxone; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Substance Withdrawal Syndrome	1996
Characterization of novel peptoid agonists for the CCK-A receptor. Regulatory peptides, 1996, Aug-27, Volume: 65, Issue:1 Topics: Adamantane; Amylases; Animals; Calcium; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Meglumine; Mice; Pancreas; Peptoids; Phenethylamines; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin	1996
The anxiolytics CI-988 and chlordiazepoxide fail to reduce immediate early gene mRNA stimulation following exposure to the rat elevated X-maze. European journal of pharmacology, 1996, Sep-26, Volume: 312, Issue:2 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Chlordiazepoxide; Gene Expression Regulation; Genes, Immediate-Early; Indoles; Male; Meglumine; Rats; RNA, Messenger; Transcriptional Activation	1996
Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988. Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:10 Topics: Animals; Hormone Antagonists; Indoles; Meglumine; Mice; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Structure-Activity Relationship	1996
Dual modulation of dopamine release from anterior nucleus accumbens through cholecystokinin-B receptor subsites. Journal of neurochemistry, 1997, Volume: 68, Issue:1 Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Cholecystokinin; Culture Media; Devazepide; Dopamine; Hormone Antagonists; Indoles; Male; Meglumine; Nucleus Accumbens; Peptide Fragments; Potassium; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tetrodotoxin	1997
Behavioral effects of CCKB receptor ligands in a validated simulation of panic anxiety in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6, Issue:4 Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Caffeine; Clonazepam; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Phenylurea Compounds; Rats; Rats, Wistar	1996
Gastrin effects on growth and exocrine secretion in the neonatal rat pancreas. Pancreas, 1997, Volume: 14, Issue:3 Topics: Amylases; Animals; Animals, Newborn; Female; Gastrins; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Meglumine; Pancreas; Pregnancy; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide	1997
Antinociceptive effects of RB101, a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by a cholecystokinin type B receptor antagonist, as revealed by noxiously evoked spinal c-Fos expression in rats. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1 Topics: Analgesics; Animals; Benzodiazepinones; Devazepide; Disulfides; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Indoles; Male; Meglumine; Pain; Phenylalanine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spinal Cord	1997
Role of vagus nerves and gastrin in the gastric phase of acid secretion in male anesthetized rats. The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1 Topics: Animals; Deoxyglucose; Gastric Acid; Gastric Mucosa; Gastrins; Hormone Antagonists; Indoles; Male; Meglumine; Peptones; Physical Stimulation; Rats; Rats, Wistar; Stomach; Vagotomy; Vagus Nerve	1997
The attenuation of morphine-conditioned place preference following chronic mild stress is reversed by a CCKB receptor antagonist. Psychopharmacology, 1997, Volume: 131, Issue:1 Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Morphine; Rats; Receptors, Cholecystokinin; Stress, Physiological; Time Factors	1997
Evaluation of biologic gastrin activity of compound CI-988 in the isolated, vascularly perfused rat stomach. Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:6 Topics: Animals; Gastric Acid; Gastrins; Histamine Release; Hormone Antagonists; Indoles; Male; Meglumine; Peptoids; Perfusion; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach	1997
CI 988, an antagonist of the cholecystokinin-B receptor, potentiates endogenous opioid-mediated antinociception at spinal level. Neuropeptides, 1997, Volume: 31, Issue:3 Topics: Analgesics; Animals; Decerebrate State; Disulfides; Dose-Response Relationship, Drug; Drug Synergism; Female; Hormone Antagonists; Indoles; Injections, Intravenous; Meglumine; Nociceptors; Opioid Peptides; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Reflex; Spinal Cord	1997
CCK-B receptors in the limbic system modulate the antidepressant-like effects induced by endogenous enkephalins. Psychopharmacology, 1997, Volume: 132, Issue:3 Topics: Amygdala; Animals; Caudate Nucleus; Disulfides; Enkephalins; Enzyme Inhibitors; Hormone Antagonists; Indoles; Injections, Intraventricular; Limbic System; Male; Meglumine; Mice; Motor Activity; Neprilysin; Nucleus Accumbens; Phenylalanine; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin	1997
The influence of 5-HT2 and 5-HT4 receptor antagonists to modify drug induced disinhibitory effects in the mouse light/dark test. British journal of pharmacology, 1997, Volume: 122, Issue:6 Topics: Animals; Avoidance Learning; Behavior, Animal; Benzodiazepinones; Darkness; Devazepide; Diazepam; Drug Antagonism; Fenclonine; Indoles; Light; Losartan; Male; Meglumine; Mice; Organophosphorus Compounds; Proline; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Ritanserin; Serotonin Antagonists; Sulfonamides	1997
Gastric effects of the CCK-B/gastrin receptor ligand CI-988 in cynomolgus monkeys. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:1 Topics: Animals; Benzodiazepinones; Gastric Acid; Gastric Mucosa; Indoles; Ligands; Macaca fascicularis; Meglumine; Phenylurea Compounds; Receptor, Cholecystokinin B; Receptors, Cholecystokinin	1998
On the role of cholecystokinin in the mediation of spinal reflex excitability in intact and axotomized rats. Neuropeptides, 1998, Volume: 32, Issue:1 Topics: Animals; Axotomy; Cholecystokinin; Electric Stimulation; Female; Indoles; Injections, Spinal; Meglumine; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Reflex; Sciatic Nerve	1998
Cholecystokinin modulates the aversive component of morphine withdrawal syndrome in rats. Neuroscience letters, 1998, Mar-06, Volume: 244, Issue:1 Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Benzodiazepinones; Cholecystokinin; Conditioning, Classical; Devazepide; Indoles; Male; Meglumine; Morphine Dependence; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Wistar; Substance Withdrawal Syndrome	1998
CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome. Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4 Topics: Acoustic Stimulation; Alcoholism; Animals; Anti-Anxiety Agents; Behavior, Animal; Central Nervous System Depressants; Dipeptides; Ethanol; Excitatory Amino Acid Agonists; Handling, Psychological; Indoles; Male; Meglumine; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Cholecystokinin; Seizures; Substance Withdrawal Syndrome	1998
Peripheral axotomy influences the in vivo release of cholecystokinin in the spinal cord dorsal horn-possible involvement of cholecystokinin-B receptors. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: Animals; Anti-Anxiety Agents; Axotomy; Cholecystokinin; Indoles; Male; Meglumine; Microdialysis; Potassium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sciatic Nerve; Spinal Cord	1998
CCK(B) antagonists protect against anxiety-related behaviour produced by ethanol withdrawal, measured using the elevated plus maze. Psychopharmacology, 1998, Volume: 137, Issue:2 Topics: Animals; Anxiety; Dipeptides; Ethanol; Indoles; Male; Maze Learning; Meglumine; Mice; Motor Activity; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Serotonin; Substance Withdrawal Syndrome	1998
YM022, a highly potent and selective CCKB antagonist inhibiting gastric acid secretion in the rat, the cat and isolated rabbit glands. Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:3 Topics: Aminopyrine; Animals; Benzodiazepines; Benzodiazepinones; Cats; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastric Fistula; Gastric Mucosa; Gastrins; Hormone Antagonists; Indoles; Male; Meglumine; Phenylurea Compounds; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin	1998
Central inhibitory dysfunctions: mechanisms and clinical implications. The Behavioral and brain sciences, 1997, Volume: 20, Issue:3 Topics: Animals; Baclofen; Central Nervous System; Cholecystokinin; GABA Agonists; Hormone Antagonists; Indoles; Ischemia; Meglumine; Narcotics; Neural Inhibition; Pain; Pain Measurement; Peripheral Nervous System; Rats; Receptors, GABA; Spinal Cord; Spinal Cord Injuries	1997
Analysis of the behaviour of selected CCKB/gastrin receptor antagonists in radioligand binding assays performed in mouse and rat cerebral cortex. British journal of pharmacology, 1999, Volume: 126, Issue:6 Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Guinea Pigs; Hormone Antagonists; Indoleacetic Acids; Indoles; Iodine Radioisotopes; Male; Meglumine; Mice; Pancreas; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Succinimides; Thiazoles; Tritium	1999
Characterization of the binding of a novel radioligand to CCKB/gastrin receptors in membranes from rat cerebral cortex. British journal of pharmacology, 1999, Volume: 126, Issue:6 Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Kinetics; Male; Meglumine; Membranes; Nootropic Agents; Pentagastrin; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tritium	1999
Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells. Molecular medicine (Cambridge, Mass.), 1999, Volume: 5, Issue:3 Topics: Animals; Antineoplastic Agents; Binding Sites; Binding, Competitive; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Colonic Neoplasms; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gastrins; Gene Expression Regulation; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Meglumine; Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Rats; Receptors, Cholecystokinin; Recombinant Proteins; Response Elements; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured	1999
Evidence that cholecystokinin receptors are not involved in the hypothalamic-pituitary-adrenal response to intraperitoneal administration of interleukin-1beta. Journal of neuroendocrinology, 1999, Volume: 11, Issue:7 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Area Under Curve; Corticosterone; Devazepide; Hypothalamo-Hypophyseal System; Indoles; Injections, Intraperitoneal; Interleukin-1; Male; Meglumine; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Recombinant Proteins	1999
Increased spinal cholecystokinin activity after systemic resiniferatoxin: electrophysiological and in situ hybridization studies. Pain, 2000, Volume: 84, Issue:1 Topics: Animals; Cholecystokinin; Decerebrate State; Diterpenes; Ganglia, Spinal; Hormone Antagonists; Indoles; Injections, Subcutaneous; Male; Meglumine; Morphine; Neurons; Neurotoxins; Pain; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Reflex; RNA, Messenger; Spinal Cord; Time Factors; Transcription, Genetic	2000
Divergent proliferative responses to a gastrin receptor ligand in synchronized and unsynchronized rat pancreatic AR42J tumour cells. Cellular signalling, 2000, Volume: 12, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Division; Gastrins; Hormone Antagonists; Indoles; Ligands; Meglumine; Pancreatic Neoplasms; Rats; Receptors, Cholecystokinin; Signal Transduction; Tumor Cells, Cultured	2000
Potentiation of opioid-induced conditioned place preference by the selective serotonin reuptake inhibitor fluoxetine. European journal of pharmacology, 2000, Feb-25, Volume: 390, Issue:1-2 Topics: Alanine; Animals; Conditioning, Operant; Disulfides; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Indoles; Male; Meglumine; Narcotics; Protease Inhibitors; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Selective Serotonin Reuptake Inhibitors	2000
Potentiation of morphine and clomipramine analgesia by cholecystokinin -B antagonist CI-988 in diabetic rats. Neuroscience letters, 2000, May-26, Volume: 286, Issue:1 Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomipramine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Meglumine; Morphine; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors	2000
Acute tolerance to continuously infused alfentanil: the role of cholecystokinin and N-methyl-D-aspartate-nitric oxide systems. Anesthesia and analgesia, 2000, Volume: 91, Issue:1 Topics: Alfentanil; Analgesia; Analgesics, Opioid; Animals; Benzodiazepinones; Cholecystokinin; Dizocilpine Maleate; Drug Tolerance; Indoles; Infusions, Intravenous; Male; Meglumine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Threshold; Phenylurea Compounds; Proglumide; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin	2000
Analgesic doses of the enkephalin degrading enzyme inhibitor RB 120 do not have discriminative stimulus properties. European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2 Topics: Alanine; Analgesics; Animals; Anti-Anxiety Agents; Discrimination Learning; Discrimination, Psychological; Disulfides; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Morphine; Protease Inhibitors; Rats; Rats, Wistar	2000
Spinal effect of the cholecystokinin-B receptor antagonist CI-988 on hyperalgesia, allodynia and morphine-induced analgesia in diabetic and mononeuropathic rats. Pain, 2000, Volume: 88, Issue:1 Topics: Analgesia; Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Drug Synergism; Hormone Antagonists; Hyperalgesia; Indoles; Injections, Intravenous; Injections, Spinal; Male; Meglumine; Morphine; Nervous System Diseases; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Touch	2000
The role of spinal cholecystokinin B receptors in thermal allodynia and hyperalgesia in diabetic mice. Brain research, 2001, Feb-23, Volume: 892, Issue:2 Topics: Animals; Capsaicin; Cholecystokinin; Diabetes Mellitus, Experimental; Enzyme Activators; Hot Temperature; Hyperalgesia; Indoles; Injections, Spinal; Male; Meglumine; Mice; Mice, Inbred ICR; Nerve Fibers; Nociceptors; Pain; Protein Kinase C; Reaction Time; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spinal Cord	2001
Evidence for a nucleus accumbens CCK2 receptor regulation of rat ventral pallidal GABA levels: a dual probe microdialysis study. Life sciences, 2000, Dec-22, Volume: 68, Issue:5 Topics: Animals; Bicuculline; Devazepide; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin	2000
Role of cholecystokinin in the reduction of endomorphin-2-induced antinociception in diabetic mice. European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2 Topics: Analgesics; Animals; Behavior, Animal; Cholecystokinin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Meglumine; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Pain; Pain Measurement; Sincalide	2001
Enhancement of the effects of a complete inhibitor of enkephalin-catabolizing enzymes, RB 101, by a cholecystokinin-B receptor antagonist in diabetic rats. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: Aminopeptidases; Animals; Diabetes Mellitus, Experimental; Disulfides; Drug Synergism; Indoles; Male; Meglumine; Naloxone; Naltrexone; Neprilysin; Pain; Pain Measurement; Phenylalanine; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors; Vocalization, Animal; Weight Loss	2001
CI-988 inhibits growth of small cell lung cancer cells. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Drug Screening Assays, Antitumor; Humans; Indoles; Lung Neoplasms; Meglumine; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tumor Cells, Cultured	2001
The neurochemical effects of anxiolytic drugs are dependent on rearing conditions in Fawn-Hooded rats. Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:3 Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Indoles; Male; Meglumine; Rats; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Dopamine D2; RNA, Messenger; Social Isolation; Tyrosine 3-Monooxygenase	2003
Pain management by a new series of dual inhibitors of enkephalin degrading enzymes: long lasting antinociceptive properties and potentiation by CCK2 antagonist or methadone. Pain, 2003, Volume: 104, Issue:1-2 Topics: Aminopeptidases; Analgesics; Animals; Disease Management; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Indoles; Male; Meglumine; Methadone; Mice; Pain; Pain Measurement; Prodrugs; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin	2003
Role of spinal cholecystokinin in neuropathic pain after spinal cord hemisection in rats. Neuroscience letters, 2009, Oct-25, Volume: 462, Issue:3 Topics: Animals; Cholecystokinin; Indoles; Male; Meglumine; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Thorax	2009
Chronic stress induces transient spinal neuroinflammation, triggering sensory hypersensitivity and long-lasting anxiety-induced hyperalgesia. Pain, 2010, Volume: 150, Issue:2 Topics: Analysis of Variance; Animals; Anxiety; Cholecystokinin; Dominance-Subordination; Hyperalgesia; Indoles; Inflammation; Male; Meglumine; Pain Measurement; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Stress, Psychological	2010
Relationship between vulnerability to reinforcing effects of morphine and activity of the endogenous cholecystokinin system in Lewis and Fischer rats. Addiction biology, 2012, Volume: 17, Issue:3 Topics: Analysis of Variance; Animals; Cholecystokinin; Conditioning, Psychological; Enkephalins; Hormone Antagonists; Indoles; Male; Meglumine; Morphine; Narcotics; Peptide Fragments; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Cholecystokinin; Reinforcement, Psychology	2012
Behavioral and cortical EEG evaluations confirm the roles of both CCKA and CCKB receptors in mouse CCK-induced anxiety. Behavioural brain research, 2013, Jan-15, Volume: 237 Topics: Adaptation, Physiological; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Brain; Brain Mapping; Brain Waves; Devazepide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Gene Expression Regulation; Indoles; Injections, Intraventricular; Male; Maze Learning; Meglumine; Mice; Mice, Inbred C57BL; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Spectrum Analysis; Tetragastrin	2013
The CCKB antagonist CI988 reduces food intake in fasted rats via a dopamine mediated pathway. Peptides, 2013, Volume: 39 Topics: Aminopyridines; Amphibian Proteins; Animals; Appetite Depressants; Dopamine; Eating; Flupenthixol; Food Deprivation; Indoles; Male; Meglumine; Peptide Hormones; Photoperiod; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Corticotropin-Releasing Hormone; Signal Transduction	2013
Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:5 Topics: Animals; Benzazepines; Diuresis; Dopamine Agonists; Dopamine Antagonists; Fenoldopam; Gastrins; Hormone Antagonists; Hypertension; Indoles; Kidney; Meglumine; Natriuresis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine D1	2013
Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Mar-12, Volume: 34, Issue:11 Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain Mapping; Cholecystokinin; Chronic Disease; Depressive Disorder; Indoles; Limbic System; Male; Meglumine; Mice; Mice, Inbred C57BL; Neural Pathways; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Receptor, Cholecystokinin B; Social Dominance; Stress, Psychological	2014
CI-988 Inhibits EGFR Transactivation and Proliferation Caused by Addition of CCK/Gastrin to Lung Cancer Cells. Journal of molecular neuroscience : MN, 2015, Volume: 56, Issue:3 Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dipeptides; ErbB Receptors; Gastrins; Gefitinib; Hormone Antagonists; Humans; Indoles; Lung Neoplasms; Meglumine; Pyrimidines; Quinazolines	2015
Contribution of CCK1 receptors to cardiovascular and respiratory effects of cholecystokinin in anesthetized rats. Neuropeptides, 2015, Volume: 54 Topics: Administration, Intravenous; Animals; Blood Pressure; Devazepide; Heart Rate; Indoles; Male; Meglumine; Nodose Ganglion; Rats; Rats, Wistar; Receptors, Cholecystokinin; Respiration; Respiratory Rate; Sincalide; Tidal Volume; Vagotomy	2015