ci 988 has been researched along with devazepide in 30 studies
| Studies (ci 988) | Trials (ci 988) | Recent Studies (post-2010) (ci 988) | Studies (devazepide) | Trials (devazepide) | Recent Studies (post-2010) (devazepide) |
|---|---|---|---|---|---|
| 147 | 8 | 14 | 780 | 5 | 42 |
| Protein | Taxonomy | ci 988 (IC50) | devazepide (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.0009 | |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | 0.0008 | |
| Cholecystokinin receptor type A | Homo sapiens (human) | 0.0002 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.245 | |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | 0.27 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (86.67) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horwell, DC; Hughes, J; Hunter, JC; Pritchard, MC; Richardson, RS; Roberts, E; Woodruff, GN | 1 |
| Capelli, AM; Carr, RA; Cassarà, P; Corsi, M; Curcuruto, O; Curotto, G; Dal Cin, M; Davalli, S; Donati, D; Feriani, A; Finch, H; Finizia, G; Gaviraghi, G; Marien, M; Pentassuglia, G; Polinelli, S; Ratti, E; Reggiani, A; Reggiani, AM; Tarzia, G; Tedesco, G; Tranquillini, ME; Trist, DG; Ursini, A; Van Amsterdam, FT | 1 |
| Branchereau, P; Champagnat, J; Denavit-Saubie, M; Roques, BP | 1 |
| Spealman, RD | 1 |
| Crawley, JN | 1 |
| Field, MJ; Hughes, J; Menzies, R; Oles, RJ; Singh, L; Vass, CA; Woodruff, GN | 1 |
| Boden, P; Hill, DR; Hughes, J; Pinnock, R; Singh, L; Woodruff, GN | 1 |
| Field, MJ; Hughes, J; Lewis, AS; Singh, L; Woodruff, GN | 1 |
| Chen, D; Ding, XQ; Håkanson, R | 1 |
| Gaw, AJ; Hills, DM; Spraggs, CF | 1 |
| Bickerdike, MJ; Dourish, CT; Fletcher, A; Marsden, CA | 1 |
| Daum, P; Hill, DR; Pinnock, RD; Suman-Chauhan, N; Woodruff, GN | 1 |
| Derrien, M; Ducos, B; Durieux, C; McCort-Tranchepain, I; Roques, BP | 1 |
| Massey, BW; Vanover, KE; Woolverton, WL | 1 |
| Chiba, T; DelValle, J; Park, J; Yamada, T | 1 |
| Blackmore, M; Doherty, E; Hirst, BH; Manning, JE | 1 |
| Boyle, SJ; McKnight, AT; Tang, KW; Woodruff, GN | 1 |
| Christoffersen, CL; Meltzer, LT; Razmpour, A; Serpa, KA | 1 |
| Hinks, GL; Hughes, J; Poat, JA | 1 |
| Brotchi, J; Camby, I; Danguy, A; Kiss, R; Martinez, J; Pasteels, JL; Salmon, I | 1 |
| Goudreau, N; Guillaume-Rousselet, N; Jagerschmidt, A; Maigret, B; Roques, BP; Vikland, ML | 1 |
| Birkemo, LS; Ervin, GN; Johnson, MF; Mosher, JT | 1 |
| Durieux, C; Léna, I; Roques, BP | 1 |
| Besson, JM; Buritova, J; Fournié-Zaluski, MC; Honore, P; Roques, BP | 1 |
| Costall, B; Naylor, RJ | 1 |
| Roques, BP; Valverde, O | 1 |
| Akil, H; Day, HE | 1 |
| Antonelli, T; Bebe, BW; Ferraro, L; Glennon, J; O'Connor, WT; Tanganelli, S; Tomasini, MC | 1 |
| Akiyama, M; Goto, Y; Inagaki, M; Izumi, H; Kaga, M; Li, H; Matsuda, Y; Matsushima, Y; Ohta, H; Seki, M; Toda, T | 1 |
| Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
1 review(s) available for ci 988 and devazepide
| Article | Year |
|---|---|
Functional role of brain CCK receptors.
Topics: Animals; Autoradiography; Benzodiazepinones; Binding Sites; Brain; Devazepide; Indoles; Meglumine; Mice; Rats; Receptors, Cholecystokinin; Sincalide | 1991 |
29 other study(ies) available for ci 988 and devazepide
| Article | Year |
|---|---|
Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Cholecystokinin; Gastrins; Indicators and Reagents; Male; Mice; Receptors, Cholecystokinin; Structure-Activity Relationship | 1991 |
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Callithrix; Cerebral Cortex; Crystallography, X-Ray; Guinea Pigs; HeLa Cells; Humans; In Vitro Techniques; Membranes; Mice; Models, Molecular; Pancreas; Radioligand Assay; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship | 2000 |
CCK modulates inhibitory synaptic transmission in the solitary complex through CCKB sites.
Topics: Animals; Benzodiazepinones; Bicuculline; Brain Stem; Cholecystokinin; Devazepide; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Indoles; Interneurons; Medulla Oblongata; Meglumine; Membrane Potentials; Microelectrodes; Phenylurea Compounds; Rats; Receptors, Cholecystokinin; Synapses; Synaptic Transmission; Vagus Nerve | 1992 |
Failure of cholecystokinin antagonists to modify the discriminative stimulus effects of cocaine.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Devazepide; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Receptors, Cholecystokinin; Reinforcement Schedule; Saimiri | 1992 |
Subtype-selective cholecystokinin receptor antagonists block cholecystokinin modulation of dopamine-mediated behaviors in the rat mesolimbic pathway.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Cholecystokinin; Darkness; Devazepide; Dopamine; Indoles; Injections, Intraperitoneal; Limbic System; Male; Meglumine; Microinjections; Motor Activity; Nucleus Accumbens; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Tegmentum Mesencephali | 1992 |
The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Carbolines; Central Nervous System Depressants; Cholecystokinin; Conflict, Psychological; Devazepide; Drug Interactions; Ethanol; Hypnotics and Sedatives; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Motor Activity; Pentagastrin; Pentobarbital; Pentylenetetrazole; Phenylurea Compounds; Postural Balance; Rats; Receptors, Cholecystokinin; Social Behavior | 1991 |
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety.
Topics: Animals; Anxiety; Benzodiazepinones; Cerebral Ventricles; Ceruletide; Chlordiazepoxide; Cholecystokinin; Devazepide; Indoles; Injections, Intraventricular; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin | 1991 |
Cholecystokinin-B receptor ligands of the dipeptoid series act as agonists on rat stomach histidine decarboxylase.
Topics: Animals; Benzodiazepinones; Devazepide; Enzyme Activation; Gastrins; Histidine Decarboxylase; Indoles; Ligands; Male; Meglumine; Phenethylamines; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stomach | 1995 |
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecystokinin; Decerebrate State; Devazepide; Dose-Response Relationship, Drug; Gastrins; Guanethidine; Heart Rate; Hormone Antagonists; Hormones; Hypertension; Indoles; Male; Meglumine; Pentagastrin; Phentolamine; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Tetragastrin | 1995 |
The influence of 5-hydroxytryptamine re-uptake blockade on CCK receptor antagonist effects in the rat elevated zero-maze.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Devazepide; Diazepam; Indoles; Male; Maze Learning; Meglumine; Niacinamide; Phenylurea Compounds; Piperazines; Piperidines; Rats; Receptors, Cholecystokinin; Selective Serotonin Reuptake Inhibitors; Zimeldine | 1994 |
The cholecystokinin-induced increase in intracellular calcium in AR42J cells is mediated by CCKB receptors linked to internal calcium stores.
Topics: Animals; Benzodiazepinones; Bridged-Ring Compounds; Calcium; Cholecystokinin; Devazepide; Dipeptides; Gastric Mucosa; Guinea Pigs; Indoles; Manganese; Meglumine; Pentagastrin; Rats; Receptors, Cholecystokinin; Tumor Cells, Cultured | 1994 |
Heterogeneity of CCK-B receptors involved in animal models of anxiety.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Benzodiazepinones; Cholecystokinin; Devazepide; Guinea Pigs; In Vitro Techniques; Indoles; Male; Meglumine; Mice; Molecular Sequence Data; Pancreas; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cholecystokinin | 1994 |
Effects of cholecystokinin antagonists on the discriminative stimulus effects of cocaine in rats and monkeys.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Devazepide; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Female; Indoles; Macaca mulatta; Male; Meglumine; Mesencephalon; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Receptors, Dopamine; Substance-Related Disorders; Synaptic Transmission | 1994 |
Distinct receptors for cholecystokinin and gastrin on canine fundic D-cells.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Cholecystokinin; Devazepide; Dogs; Gastric Fundus; Gastric Mucosa; Gastrins; Indoles; Kinetics; Meglumine; Receptors, Cholecystokinin; Sincalide; Somatostatin | 1993 |
Autocrine growth stimulation of human renal Wilms' tumour G401 cells by a gastrin-like peptide.
Topics: Benzamides; Benzodiazepinones; Cell Division; Devazepide; Gastrins; Humans; Indoles; Kidney Neoplasms; Meglumine; Phenylurea Compounds; Proglumide; Receptors, Cholecystokinin; Tumor Cells, Cultured; Wilms Tumor | 1994 |
Characterization of CCK receptors in a novel smooth muscle preparation from the guinea-pig stomach by use of the selective antagonists CI-988, L-365,260 and devazepide.
Topics: Animals; Benzodiazepinones; Carbachol; Cholecystokinin; Devazepide; Gastric Mucosa; Gastrins; Guinea Pigs; In Vitro Techniques; Indoles; Male; Meglumine; Muscle Contraction; Muscle, Smooth; Phenylurea Compounds; Receptors, Cholecystokinin; Stomach | 1993 |
Comparison of the effects of the cholecystokinin-B receptor antagonist, PD 134308, and the cholecystokinin-A receptor antagonist, L-364,718, on dopamine neuronal activity in the substantia nigra and ventral tegmental area.
Topics: Animals; Apomorphine; Benzodiazepinones; Cholecystokinin; Devazepide; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Indoles; Male; Meglumine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Substantia Nigra; Tegmentum Mesencephali | 1993 |
Changes in hypothalamic cholecystokininA and cholecystokininB receptor subtypes and associated neuropeptide expression in response to salt-stress in the rat and mouse.
Topics: Animals; Autoradiography; Benzodiazepinones; Cholecystokinin; Devazepide; Hormone Antagonists; Hypothalamus; In Situ Hybridization; Indoles; Male; Meglumine; Mice; Mice, Inbred Strains; Neuronal Plasticity; Neuropeptides; Oligonucleotide Probes; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger; Saline Solution, Hypertonic; Succinimides | 1995 |
Influence of gastrin on human astrocytic tumor cell proliferation.
Topics: Amino Acid Sequence; Astrocytoma; Autoradiography; Benzodiazepinones; Brain Neoplasms; Cell Division; Cholecystokinin; Devazepide; Gastrins; Hormone Antagonists; Humans; Indoles; Meglumine; Molecular Sequence Data; Peptide Fragments; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Thymidine; Tritium; Tumor Cells, Cultured | 1996 |
His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity.
Topics: Animals; Arginine; Base Sequence; Benzodiazepinones; Cholecystokinin; Devazepide; Histidine; Indoles; Meglumine; Models, Molecular; Molecular Sequence Data; Phenylurea Compounds; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tetragastrin | 1996 |
Several roles of CCKA and CCKB receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning.
Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Psychological; Devazepide; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Lithium Chloride; Male; Meglumine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Taste | 1996 |
Dual modulation of dopamine release from anterior nucleus accumbens through cholecystokinin-B receptor subsites.
Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Cholecystokinin; Culture Media; Devazepide; Dopamine; Hormone Antagonists; Indoles; Male; Meglumine; Nucleus Accumbens; Peptide Fragments; Potassium; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tetrodotoxin | 1997 |
Antinociceptive effects of RB101, a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by a cholecystokinin type B receptor antagonist, as revealed by noxiously evoked spinal c-Fos expression in rats.
Topics: Analgesics; Animals; Benzodiazepinones; Devazepide; Disulfides; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Indoles; Male; Meglumine; Pain; Phenylalanine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spinal Cord | 1997 |
The influence of 5-HT2 and 5-HT4 receptor antagonists to modify drug induced disinhibitory effects in the mouse light/dark test.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzodiazepinones; Darkness; Devazepide; Diazepam; Drug Antagonism; Fenclonine; Indoles; Light; Losartan; Male; Meglumine; Mice; Organophosphorus Compounds; Proline; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Ritanserin; Serotonin Antagonists; Sulfonamides | 1997 |
Cholecystokinin modulates the aversive component of morphine withdrawal syndrome in rats.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Benzodiazepinones; Cholecystokinin; Conditioning, Classical; Devazepide; Indoles; Male; Meglumine; Morphine Dependence; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1998 |
Evidence that cholecystokinin receptors are not involved in the hypothalamic-pituitary-adrenal response to intraperitoneal administration of interleukin-1beta.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Area Under Curve; Corticosterone; Devazepide; Hypothalamo-Hypophyseal System; Indoles; Injections, Intraperitoneal; Interleukin-1; Male; Meglumine; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Recombinant Proteins | 1999 |
Evidence for a nucleus accumbens CCK2 receptor regulation of rat ventral pallidal GABA levels: a dual probe microdialysis study.
Topics: Animals; Bicuculline; Devazepide; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin | 2000 |
Behavioral and cortical EEG evaluations confirm the roles of both CCKA and CCKB receptors in mouse CCK-induced anxiety.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Brain; Brain Mapping; Brain Waves; Devazepide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Gene Expression Regulation; Indoles; Injections, Intraventricular; Male; Maze Learning; Meglumine; Mice; Mice, Inbred C57BL; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Spectrum Analysis; Tetragastrin | 2013 |
Contribution of CCK1 receptors to cardiovascular and respiratory effects of cholecystokinin in anesthetized rats.
Topics: Administration, Intravenous; Animals; Blood Pressure; Devazepide; Heart Rate; Indoles; Male; Meglumine; Nodose Ganglion; Rats; Rats, Wistar; Receptors, Cholecystokinin; Respiration; Respiratory Rate; Sincalide; Tidal Volume; Vagotomy | 2015 |