Page last updated: 2024-09-05

ci 966 and n-(4,4-diphenyl-3-butenyl)nipecotic acid

ci 966 has been researched along with n-(4,4-diphenyl-3-butenyl)nipecotic acid in 2 studies

Compound Research Comparison

Studies (ci 966)	Trials (ci 966)	Recent Studies (post-2010) (ci 966)	Studies (n-(4,4-diphenyl-3-butenyl)nipecotic acid)	Trials (n-(4,4-diphenyl-3-butenyl)nipecotic acid)	Recent Studies (post-2010) (n-(4,4-diphenyl-3-butenyl)nipecotic acid)
14	0	4	121	0	22

Protein Interaction Comparison

Protein	Taxonomy	n-(4,4-diphenyl-3-butenyl)nipecotic acid (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	0.6918
Sodium- and chloride-dependent GABA transporter 1	Homo sapiens (human)	0.165
Sodium- and chloride-dependent GABA transporter 1	Mus musculus (house mouse)	0.4099

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borden, LA; Branchek, TA; Gluchowski, C; Murali Dhar, TG; Smith, KE; Weinshank, RL	1
Chatton, JY; Magistretti, PJ; Pellerin, L	1

Other Studies

2 other study(ies) available for ci 966 and n-(4,4-diphenyl-3-butenyl)nipecotic acid

Article	Year
Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2 Topics: Animals; Anticonvulsants; Carrier Proteins; Cell Line; Cloning, Molecular; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Oximes; Pyridines; Rats; Recombinant Proteins; Structure-Activity Relationship; Tiagabine; Transfection	1994
GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission. Proceedings of the National Academy of Sciences of the United States of America, 2003, Oct-14, Volume: 100, Issue:21 Topics: Animals; Astrocytes; Biological Transport, Active; Brain; Cells, Cultured; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Fluid; Lactic Acid; Magnesium; Mice; Nipecotic Acids; Pyridines; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission	2003

Article

Year

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2

Topics: Animals; Anticonvulsants; Carrier Proteins; Cell Line; Cloning, Molecular; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Oximes; Pyridines; Rats; Recombinant Proteins; Structure-Activity Relationship; Tiagabine; Transfection

1994

GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission.

Proceedings of the National Academy of Sciences of the United States of America, 2003, Oct-14, Volume: 100, Issue:21

Topics: Animals; Astrocytes; Biological Transport, Active; Brain; Cells, Cultured; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Fluid; Lactic Acid; Magnesium; Mice; Nipecotic Acids; Pyridines; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission

2003