ci 924 has been researched along with gemfibrozil in 5 studies
*Gemfibrozil: A lipid-regulating agent that lowers elevated serum lipids primarily by decreasing serum triglycerides with a variable reduction in total cholesterol. [MeSH]
*Gemfibrozil: A lipid-regulating agent that lowers elevated serum lipids primarily by decreasing serum triglycerides with a variable reduction in total cholesterol. [MeSH]
| Studies (ci 924) | Trials (ci 924) | Recent Studies (post-2010) (ci 924) | Studies (gemfibrozil) | Trials (gemfibrozil) | Recent Studies (post-2010) (gemfibrozil) |
|---|---|---|---|---|---|
| 9 | 1 | 4 | 1,483 | 359 | 297 |
| Protein | Taxonomy | ci 924 (IC50) | gemfibrozil (IC50) |
|---|---|---|---|
| Cytochrome P450 2C8 | Homo sapiens (human) | 4.1 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 7.0795 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 4.0738 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoefle, M; Maxwell, RE; Sircar, I | 1 |
| Corder, CN; Kloer, HU; Price, MD | 1 |
| Hofstra, AH; King, LM; Walker, RM | 2 |
| Chen, CH; Huang, KY; Kor, CT; Li, YR; Lin, CH; Lin, SH; Wang, BY | 1 |
1 trial(s) available for ci 924 and gemfibrozil
| Article | Year |
|---|---|
CI-924 effects on plasma lipids in patients with type II and type IV hyperlipoproteinaemia.
Topics: Apolipoproteins; Dose-Response Relationship, Drug; Double-Blind Method; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipids; Lipoproteins; Male; Middle Aged | 1989 |
4 other study(ies) available for ci 924 and gemfibrozil
| Article | Year |
|---|---|
Phenylenebis(oxy)bis[2,2-dimethylpentanoic acid]s: agents that elevate high-density lipoproteins.
Topics: Animals; Biological Assay; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Gemfibrozil; Hypolipidemic Agents; Indicators and Reagents; Lipoproteins, HDL; Lipoproteins, LDL; Male; Pentanoic Acids; Rats; Structure-Activity Relationship; Valerates | 1983 |
Peroxisome proliferation and microsomal enzyme induction by the hypolipidemic CI-924 in rats and mice: relationship to tumorgenicity.
Topics: Animals; Blotting, Western; Body Weight; Carcinogenicity Tests; Carcinogens; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Gemfibrozil; Hypolipidemic Agents; Male; Mice; Mice, Inbred Strains; Microbodies; Microsomes, Liver; Organ Size; Rats; Rats, Wistar; Sex Characteristics; Species Specificity | 1995 |
Early effects of CI-924 on hepatic peroxisome proliferation, microsomal enzyme induction, PCNA, and apoptosis in B6C3F1 mice and Wistar rats.
Topics: Animals; Apoptosis; Blotting, Western; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Female; Gemfibrozil; Hypolipidemic Agents; Liver; Male; Mice; Microbodies; Mixed Function Oxygenases; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Time Factors; Transcription Factors | 1997 |
The impact of the duration of the integrated disease management program on COPD-related outcomes.
Topics: Disease Management; Female; Gemfibrozil; Humans; Male; Pulmonary Disease, Chronic Obstructive; Retrospective Studies | 2023 |