chrysin and cirsiliol

chrysin has been researched along with cirsiliol* in 1 studies

Reviews

1 review(s) available for chrysin and cirsiliol

Article	Year
GABA(A)-receptor ligands of flavonoid structure. Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8 This review describes the new research developments that have established the CNS-activity of some natural flavonoids. The properties of flavone, chrysin, apigenin and cirsiliol are described and a survey of the occurrence of ligands for the benzodiazepine binding site in the flavonoid field is attempted. Natural compounds, structurally related to flavonoids and with similar CNS-activities, are also included. A medicinal chemistry approach to improve the biochemical and pharmacological properties of the flavone nucleus is described alongside with the enumeration of the principal achievements obtained to date. Quantitative structure-activity relationships studies leading to the formulation of pharmacophore models presumably describing the characteristics of the flavone-binding site in the GABA(A)-receptor are summarized. Topics: Animals; Apigenin; Benzodiazepines; Binding Sites; Flavones; Flavonoids; GABA Agents; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, GABA-A	2002

Article

Year

GABA(A)-receptor ligands of flavonoid structure.

Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8

This review describes the new research developments that have established the CNS-activity of some natural flavonoids. The properties of flavone, chrysin, apigenin and cirsiliol are described and a survey of the occurrence of ligands for the benzodiazepine binding site in the flavonoid field is attempted. Natural compounds, structurally related to flavonoids and with similar CNS-activities, are also included. A medicinal chemistry approach to improve the biochemical and pharmacological properties of the flavone nucleus is described alongside with the enumeration of the principal achievements obtained to date. Quantitative structure-activity relationships studies leading to the formulation of pharmacophore models presumably describing the characteristics of the flavone-binding site in the GABA(A)-receptor are summarized.

Topics: Animals; Apigenin; Benzodiazepines; Binding Sites; Flavones; Flavonoids; GABA Agents; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2002