chromopyrrolic-acid has been researched along with staurosporine-aglycone* in 1 studies
1 other study(ies) available for chromopyrrolic-acid and staurosporine-aglycone
Article | Year |
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Production of chromopyrrolic acid by coexpression of inkOD in a heterologous host Streptomyces albus.
Two ink genes, inkO and inkD, responsible for the earliest steps of K252a biosynthetic pathway, from Nonomurea longicantena JCM 11136 were heterologously coexpressed in Streptomycesalbus J1074. The resultant strain accumulated compound that was purified by HPLC and studied by NMR. Coexpression of inkOD yielded chromopyrrolic acid, the key intermediate in an indolocarbazole biosynthesis. Topics: Carbazoles; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Design; Indole Alkaloids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Multigene Family; Pyrroles; Streptomyces; Tryptophan | 2009 |