choline and s-adenosylmethionine

choline has been researched along with s-adenosylmethionine in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (34.38)	18.7374
1990's	12 (12.50)	18.2507
2000's	13 (13.54)	29.6817
2010's	29 (30.21)	24.3611
2020's	9 (9.38)	2.80

Authors

Authors	Studies
Bakovic, M; Schenkel, LC; Sivanesan, S; Taylor, A; Verbrugghe, A; Wuyts, B; Zhang, J	1
Berge, RK; Bjørndal, B; Bohov, P; Bruheim, I; Nordrehaug, JE; Ramsvik, MS; Rostrup, E; Svardal, A	1
Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X	1
Feng, T; Kenéz, Á; Mann, S; Nydam, DV; Overton, TR; Wakshlag, JJ; Xu, W; Yepes, FL	1
Burton, EG; Metzenberg, RL	2
Galeone, F; Guarguaglini, M; Saba, P; Salvadorini, F	1
Kiss, Z	1
Petri, WA; Poirier, LA	1
Edwards, CH; Edwards, GA; Freeburne, MM; Jones, EG; Seo, CW; Sherman, L; Stacey, RE; Wade, WD	1
Barbier, M; Kerr, SJ; Lederer, E; Tekitek, A	1
Poirier, LA; Wainfan, E	1
Dreyfus, H; Ferret, B; Hubsch, A; Massarelli, R	1
Long, JP; Sheff, KY; Yorek, MA	1
Andriamampandry, C; Freysz, L; Kanfer, JN; Massarelli, R	1
Jaffe, JJ; Srivastava, AK	1
Bloch, K; Chin, J	1
Finkelstein, JD; Harris, BJ; Martin, JJ	1
Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ	1
Snoswell, AM; Xue, GP	1
Young, DL	1
Dewhurst, SA; Weinreich, D	1
Thompson, W; Wong, ER	1
Kates, M; Marshall, MO	1
Abdel-Latif, AA; Morganstern, RD	1
Hallman, M; Raivio, K	1
Lester, RL; Waechter, CJ	1
Lees, GJ; McCaman, MW; McCaman, RE	1
Rigoli, A	1
Acheampong-Mensah, D; Feuer, G	1
Jensen, LS; Kushwaha, RP	1
Blume, AJ; Farber, JL; Nirenberg, MW; Rosenberg, RN; Schrier, BK; Thompson, EJ; Wilson, SH	1
Fitzgerald, PJ; Marsh, WH; Parsa, I	1
Demain, AL; White, RF	1
Adler, M; Cantoni, GL; Chiang, PK; de Blas, A; Nirenberg, M; Shih, M	1
Hoffman, RM	1
Benevenga, NJ	1
Benzi, G; Curti, D; Polgatti, M; Villa, RF	1
Cascales, C; Cascales, M; Santos-Ruiz, A; Santos-Ruiz, MR	1
Poirier, LA; Shivapurkar, N	1
Bartoli, E; Daino, L; Feo, F; Pascale, R; Pirisi, L; Satta, A; Zanetti, S	1
Hayakawa, T; She, QB; Tsuge, H	1
Barry, JA; Gillies, RJ; Ross, BD	1
Bussière, M; Campenot, RB; Pan, D; Vance, DE; Vance, JE	1
Jenden, DJ; Vargas, HM	1
Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL	1
Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH	1
Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME	1
Alpert, JE; Bottiglieri, T; Fava, M; Kolsky, AR; Magni, G; Moore, C; Moroz, G; Nierenberg, AA; Renshaw, P; Rosenbaum, JF; Spillmann, M	1
Capdevila, A; Jenden, DJ; Levy, HL; Mudd, SH; Roch, M; Wagner, C	1
Ashihara, H; Baba, S; Suzuki, M; Yasumoto, E	1
Mar, MH; Song, J; Zeisel, SH; Zhu, X	1
Choi, JY; Mamoun, CB; Pessi, G; Reynolds, JM; Voelker, DR	1
Augspurger, NR; Baker, DH; Garrow, TA; Scherer, CS	1
Green, RM; Igolnikov, AC	1
Chen, TS; de Villiers, WJ; Im, HJ; McClain, CJ; Oz, HS	1
Maloney, CA; Rees, WD; Wilson, FA	1
Allen, RH; Barić, I; Buist, NR; Glenn, B; Mudd, SH; Pogribny, I; Schulze, A; Stabler, S; Vugrek, O; Wagner, C; Zeisel, SH	1
Batra, V; Mishra, KP	1
Bishop, JR; Bogarapu, S; Krueger, CD; Pavuluri, MN	1
Copple, BL; Gyamfi, M; He, L; Wan, YJ; Wortham, M	1
Blom, HJ; Boulanger, Y; Debray, FG; Decarie, JC; Jakobs, C; Khiat, A; Lambert, M; Levy, E; Lortie, A; Mitchell, GA; Orquin, J; Ramos, F; Roy, MS; Struys, E; Verhoeven, NM	1
Batra, V; Devasagayam, TP; Sridhar, S	1
Abratte, CM; Caudill, MA; Shin, W; Vermeylen, F; Yan, J	1
Caballeria, J; Caballero, F; Elena, M; Fernández, A; Fernández-Checa, JC; Fucho, R; García-Ruiz, C; Martínez, L; Matías, N; Morales, A	1
Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT	1
da Costa, KA; Fischer, LM; Sanders, LM; Zeisel, SH	1
Garrow, TA; Mehedint, MG; Teng, YW; Zeisel, SH	1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR	1
Cruz, D; Delgado, JM; Jiménez-Capdeville, ME; Ríos, R; Santoyo, ME; Zarazúa, S	1
Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM	1
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q	1
Awaji, H; Horie, K; Kim, M; Nakata, R; Sugiyama, A	1
Mehedint, MG; Zeisel, SH	1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH	1
Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D	1
Obeid, R	1
Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G	1
Cardoso, JF; da Silva, LE; de Castro, GS; Deminice, R; Dos Reis Silveira, L; Frajacomo, FT; Francisco, LV; Jordao, AA; Teodoro, BG	1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y	1
Chmiel, KJ; Halsted, CH; Kharbanda, KK; Kim, K; Medici, V; Olson, K; Rutledge, JC; Shibata, NM; Su, RJ; Syed, R; Yokoyama, A	1
Arning, E; Bahous, RH; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Hou, W; Jerome-Majewska, LA; Malysheva, OV; Rozen, R	1
Zeisel, S	1
Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A	1
Balskus, EP; Bodea, S	1
Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R	1
Arima, H; Fujii, T; Izu, H; Yamashita, S	1
Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA	1
Elango, R	1
Mohmmed, A; Narwal, M; Sheokand, PK; Thakur, V	1
Baylin, A; Burant, CF; Dolinoy, DC; Domino, SE; Goodrich, JM; LaBarre, JL; McCabe, CF; Padmanabhan, V; Treadwell, MC	1
Akison, LK; Cuffe, JSM; Kumar, V; Moritz, KM; Steane, SE	1
Caton, JS; Crouse, MS; Cushman, RA; Dahlen, CR; Freetly, HC; King, LE; Lee, RT; Lindholm-Perry, AK; Neville, BW; Oliver, WT; Reynolds, LP; Syring, JG; Ward, AK	1
Bare, A; Etoroma, D; Lee, SG; Thomas, J	1
Aiba, T; Hara, S; Harada, S; Hirabayashi, T; Ikeda, K; Kaneko, M; Kasahara, K; Kawaguchi, M; Kikuchi, N; Kita, Y; Kiyonari, H; Kobayashi, T; Kurano, M; Mikami, K; Miki, Y; Mouri, M; Murakami, M; Nakata, R; Nishito, Y; Sato, H; Soga, T; Takamiya, R; Taketomi, Y; Tokuoka, SM; Yatomi, Y; Yoda, E; Yokoyama, K	1
Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H	1

Reviews

8 review(s) available for choline and s-adenosylmethionine

Article	Year
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis. Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2 Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40	1984
Evidence for alternative pathways of methionine catabolism. Advances in nutritional research, 1984, Volume: 6 Topics: Animals; Betaine; Carbon Dioxide; Choline; Decarboxylation; Diet; Homocystinuria; Humans; Liver; Methionine; Models, Biological; Oxidation-Reduction; Propionates; S-Adenosylmethionine; Sarcosine; Transaminases	1984
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet. The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine	2006
Complementary medicines in pediatric bipolar disorder. Minerva pediatrica, 2008, Volume: 60, Issue:1 Topics: Adolescent; Bipolar Disorder; Child; Choline; Complementary Therapies; Drug Therapy, Combination; Fatty Acids, Omega-3; Humans; Inositol; Lecithins; Nootropic Agents; Quality of Life; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Surface-Active Agents; Treatment Outcome; Vitamin B Complex	2008
Choline's role in maintaining liver function: new evidence for epigenetic mechanisms. Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:3 Topics: Animals; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Folic Acid; Gene Expression; Histones; Humans; Liver; Liver Cirrhosis; Models, Animal; Polymorphism, Genetic; S-Adenosylmethionine	2013
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway. Nutrients, 2013, Sep-09, Volume: 5, Issue:9 Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine	2013
Choline, Other Methyl-Donors and Epigenetics. Nutrients, 2017, Apr-29, Volume: 9, Issue:5 Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cyclin-Dependent Kinase Inhibitor Proteins; Diet; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histones; Humans; Liver Neoplasms; Meta-Analysis as Topic; Mice; Models, Animal; Phenotype; S-Adenosylhomocysteine; S-Adenosylmethionine	2017
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition. The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1 Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur	2020

Trials

4 trial(s) available for choline and s-adenosylmethionine

Article	Year
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. Lipids in health and disease, 2015, Dec-15, Volume: 14 Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Erythrocytes; Euphausiacea; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, VLDL; Male; Methylamines; Particle Size; Pilot Projects; Triglycerides	2015
Folate nutriture alters choline status of women and men fed low choline diets. The Journal of nutrition, 1999, Volume: 129, Issue:3 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine	1999
Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men. The Journal of nutrition, 2010, Volume: 140, Issue:5 Topics: Adolescent; Adult; Choline; Choline Deficiency; Diet; DNA Damage; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid Deficiency; Genetic Markers; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Nutrition Policy; Nutritional Requirements; Polymorphism, Genetic; S-Adenosylmethionine; Young Adult	2010
Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. The American journal of clinical nutrition, 2011, Volume: 93, Issue:5 Topics: Adolescent; Adult; Aged; Biomarkers; Cholesterol, Dietary; Choline; Choline Deficiency; Docosahexaenoic Acids; Female; Genetic Association Studies; Humans; Liver; Male; Menopause; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult	2011

Other Studies

84 other study(ies) available for choline and s-adenosylmethionine

Article	Year
Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency. The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:11 Topics: Acylation; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Carnitine; Choline; Dietary Supplements; Fatty Acids; Gene Expression Regulation; Liver; Mice, Mutant Strains; Phosphatidylcholines; Phosphatidylserines; RNA Nucleotidyltransferases; Triglycerides; Weight Gain	2015
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. JAMA cardiology, 2018, 03-01, Volume: 3, Issue:3 Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Female; Humans; Hypertension; Kynurenine; Male; Renal Insufficiency, Chronic; Stroke Volume; Transcatheter Aortic Valve Replacement; Ventricular Remodeling	2018
Effects of dietary branched-chain amino acid supplementation on serum and milk metabolome profiles in dairy cows during early lactation. Journal of dairy science, 2022, Volume: 105, Issue:10 Topics: Amino Acids, Branched-Chain; Animals; Antioxidants; Carnitine; Cattle; Choline; Diet; Dietary Supplements; Fatty Acids; Female; Glucose; Glutathione; Humans; Insulins; Lactation; Lipids; Metabolome; Milk; Nitrogen; Phosphorylcholine; Urea	2022
Regulation of methionine biosythesis in Neurospora crassa. Archives of biochemistry and biophysics, 1975, Volume: 168, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Cell Division; Choline; Enzyme Activation; Glycine Hydroxymethyltransferase; Methionine; Mutation; Neurospora; Neurospora crassa; S-Adenosylmethionine; Tetrahydrofolate Dehydrogenase	1975
Effect of intravenous injection of CDP-choline, S-adenosyl-methionine and citiolone in subjects with hyperlipemia. Artery, 1979, Volume: 5, Issue:2 Topics: Adult; Cholesterol; Choline; Cytidine Diphosphate Choline; Female; Humans; Hyperlipidemias; In Vitro Techniques; Injections, Intravenous; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; S-Adenosylmethionine; Thiophenes; Triglycerides	1979
Role of a specific choline pool in sphingomyelin synthesis in rat heart. The Biochemical journal, 1977, Dec-15, Volume: 168, Issue:3 Topics: Animals; Choline; Ethanolamines; In Vitro Techniques; Kinetics; Male; Myocardium; Phosphatidylcholines; Phospholipids; Phosphorus; Rats; S-Adenosylmethionine; Sphingomyelins; Tissue Distribution	1977
A methionine-reversible folate deficiency in rats following the acute administration of diethylnitrosamine and alpha-naphthylisothiocyanate. Chemico-biological interactions, 1977, Volume: 17, Issue:1 Topics: 1-Naphthylisothiocyanate; Animals; Choline; Diet; Diethylnitrosamine; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Male; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Thiocyanates; Time Factors	1977
Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat. The Journal of nutrition, 1977, Volume: 107, Issue:10 Topics: Adenosine; Aminobutyrates; Animals; Body Weight; Butyrates; Choline; Cysteine; Deoxyadenosines; Homoserine; Male; Methionine; Rats; S-Adenosylmethionine; Thionucleosides	1977
Transfer of the methyl group of methionine to choline and to tRNA in the honeybee Apis mellifica L. Biochimie, 1975, Volume: 57, Issue:10 Topics: Animals; Bees; Choline; Cytosine; Fatty Acids; Guanine; Lipids; Methylation; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases	1975
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression. Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12	1992
Exogenous gangliosides may affect methylation mechanisms in neuronal cell cultures. Neurochemical research, 1991, Volume: 16, Issue:2 Topics: Animals; Brain; Cells, Cultured; Chemical Precipitation; Chick Embryo; Choline; DNA; Ethanolamine; Ethanolamines; Gangliosides; Methionine; Methylation; Molecular Weight; Neurons; Phospholipids; RNA; S-Adenosylmethionine; Sulfur Radioisotopes; Trichloroacetic Acid; Tritium	1991
Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: Animals; Biphenyl Compounds; Choline; Ethanolamine; Ethanolamines; Mice; Neuroblastoma; Phosphatidylcholines; Phospholipids; Piperidines; S-Adenosylmethionine; Tumor Cells, Cultured	1991
A rat brain cytosolic N-methyltransferase(s) activity converting phosphorylethanolamine into phosphorylcholine. Biochemical and biophysical research communications, 1990, Sep-14, Volume: 171, Issue:2 Topics: Animals; Brain; Cell Fractionation; Choline; Cytosol; Ethanolamines; Kinetics; Male; Methyltransferases; Phosphorylcholine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Subcellular Fractions	1990
Phosphatidylcholine synthesis in adult Dirofilaria immitis females. International journal for parasitology, 1985, Volume: 15, Issue:1 Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Dirofilaria immitis; Female; Filarioidea; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine	1985
Phosphatidylcholine synthesis in yeast. Journal of lipid research, 1988, Volume: 29, Issue:1 Topics: Choline; Cytidine Diphosphate Choline; Ethionine; Methionine; Methylation; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae	1988
Methionine metabolism in mammals. The methionine-sparing effect of cystine. The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine	1988
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets. Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1 Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors	1986
Regulation of methyl group metabolism in lactating ewes. Biochemistry international, 1985, Volume: 11, Issue:3 Topics: Animals; Choline; Creatine; Creatinine; Female; Lactation; Liver; Methyltransferases; Milk; Pancreas; Pregnancy; S-Adenosylmethionine; Sheep	1985
Estradiol- and testosterone-induced alterations in phosphatidylcholine and triglyceride synthesis in hepatic endoplasmic reticulum. Journal of lipid research, 1971, Volume: 12, Issue:5 Topics: Acyltransferases; Animal Nutritional Physiological Phenomena; Animals; Benzoates; Body Weight; Carbon Isotopes; Castration; Choline; Coenzyme A; Cytosine Nucleotides; Depression, Chemical; Diet; Endoplasmic Reticulum; Estradiol; Female; Glycerides; Injections, Subcutaneous; Lipotropic Agents; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phosphotransferases; Propionates; Rats; S-Adenosylmethionine; Stimulation, Chemical; Testosterone; Triglycerides	1971
Effects of long-term organ culture on neurotransmitter metabolism in the ganglia of Aplysia californica. Journal of neurobiology, 1974, Volume: 5, Issue:1 Topics: Acetylcholinesterase; Acetyltransferases; Action Potentials; Amino Acids; Animals; Carboxy-Lyases; Carnitine; Catechol O-Methyltransferase; Choline; Electrophysiology; Evoked Potentials; Ganglia; Glucosephosphate Dehydrogenase; Nerve Tissue Proteins; Neurotransmitter Agents; Organ Culture Techniques; S-Adenosylmethionine; Synaptic Transmission; Time Factors	1974
Novel mutation causing derepression of several enzymes of sulfur metabolism in Neurospora crassa. Journal of bacteriology, 1972, Volume: 109, Issue:1 Topics: Alkaline Phosphatase; Alleles; Autoradiography; Cell-Free System; Choline; Chromatography, Ion Exchange; Chromosome Mapping; Crosses, Genetic; Culture Media; Electrophoresis; Enzyme Repression; Genes; Genetics, Microbial; Homoserine; Hydro-Lyases; Hydrolases; Isocitrates; Lyases; Methionine; Mutation; Neurospora; Neurospora crassa; Pentosyltransferases; S-Adenosylmethionine; Sucrase; Sulfatases; Sulfates; Sulfur; Sulfur Isotopes; Sulfurtransferases; Transferases	1972
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver. Biochimica et biophysica acta, 1972, Feb-21, Volume: 260, Issue:2 Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium	1972
Biosynthesis of nitrogenous phospholipids in spinach leaves. Canadian journal of biochemistry, 1974, Volume: 52, Issue:6 Topics: Calcium; Carbon Radioisotopes; Carboxy-Lyases; Choline; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Cytosine Nucleotides; Escherichia coli; Ethanolamines; Microsomes; Phosphatidylcholines; Phosphatidylethanolamines; Plant Cells; Plants; S-Adenosylmethionine; Serine; Silicon Dioxide; Transferases; Ultrasonics	1974
Incorporation of (14-C) ethanolamine and (3-H) methionine into phospholipids of rat brain and liver in vivo and in vitro. Journal of neurobiology, 1974, Volume: 5, Issue:5 Topics: Animals; Brain; Carbon Radioisotopes; Choline; Ethanolamines; In Vitro Techniques; Inositol; Liver; Male; Methionine; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; S-Adenosylmethionine; Sphingomyelins; Synaptosomes; Tritium	1974
Studies on the biosynthesis of disaturated lecithin of the lung: the importance of the lysolecithin pathway. Pediatric research, 1974, Volume: 8, Issue:11 Topics: Animals; Carbon Radioisotopes; Choline; Female; Glycerol; Isotope Labeling; Lung; Lysophosphatidylcholines; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Pulmonary Surfactants; Rabbits; S-Adenosylmethionine; Time Factors; Tritium	1974
Differential regulation of the N-methyl transferases responsible for phosphatidylcholine synthesis in Saccharomyces cerevisiae. Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:1 Topics: Carbon Isotopes; Cell-Free System; Choline; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Culture Media; Ethanolamines; Fatty Acids; Kinetics; Methyltransferases; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors	1973
Liquid cation exchange--a basis for sensitive radiometric assays for aromatic amino acid decarboxylases. Analytical biochemistry, 1972, Volume: 45, Issue:1 Topics: Aminobutyrates; Animals; Carbon Isotopes; Carboxy-Lyases; Carnitine; Choline; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Drosophila melanogaster; Glutamates; Histamine; Histidine; Hydrogen-Ion Concentration; Ion Exchange; Methods; Norepinephrine; Organophosphorus Compounds; Phenethylamines; S-Adenosylmethionine; Serotonin; Tritium; Tyramine; Tyrosine; Tyrosine Decarboxylase	1972
[Biological transmethylations]. Il Farmaco; edizione pratica, 1973, Volume: 28, Issue:8 Topics: Choline; Creatine; Histamine; Methylation; S-Adenosylmethionine; Tyrosine	1973
Relation between the hepatic action of drugs and the synthesis of subcellular structures. International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:1 Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Choline; Dactinomycin; Deficiency Diseases; Diet; Drug Interactions; In Vitro Techniques; Liver; Male; Methionine; Methylation; Methyltransferases; Microsomes, Liver; Phenobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats; S-Adenosylmethionine; Subcellular Fractions	1974
In vivo and in vitro utilization of labeled precursors for choline synthesis in mature Japanese quail as compared to rats. The Journal of nutrition, 1974, Volume: 104, Issue:7 Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Chickens; Choline; Coturnix; Ethanolamines; Female; In Vitro Techniques; Liver; Methionine; Methylamines; Methylation; Methyltransferases; Nutritional Requirements; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine; Serine; Species Specificity	1974
Markers for gene expression in cultured cells from the nervous system. The Journal of biological chemistry, 1972, May-25, Volume: 247, Issue:10 Topics: Acetylcholinesterase; Acyltransferases; Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Catechol O-Methyltransferase; Cell Line; Cells, Cultured; Choline; Coenzyme A; Genes; Glutamates; Glycolates; Humans; Methyltransferases; Mice; Mice, Inbred Strains; Neuroblastoma; Neuroglia; Rats; S-Adenosylmethionine	1972
Pancreas acinar cell differentiation. V. Significance of methyl groups in morphologic and enzymatic development. Experimental cell research, 1972, Volume: 73, Issue:1 Topics: Amylases; Animals; Choline; Chymotrypsin; Culture Media; Cysteine; Cystine; Lipase; Methionine; Methylation; Microscopy, Electron; Organ Culture Techniques; Pancreas; Rats; RNA, Transfer; S-Adenosylmethionine	1972
Catabolism of betaine and its relationship to cobalamin overproduction. Biochimica et biophysica acta, 1971, Apr-20, Volume: 237, Issue:1 Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12	1971
Inhibitors of CDP-choline synthesis, action potential calcium channels, and stimulus-secretion coupling. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14 Topics: Acetylcholine; Action Potentials; Animals; Calcium; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Deoxyadenosines; Hybrid Cells; Ion Channels; Mice; Motor Endplate; Nucleotidyltransferases; Phosphatidylcholines; Rats; Receptors, Nicotinic; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin	1984
Synaptosomes and mitochondria from rat brain cerebral cortex: in vivo interference on some enzymatic activities by SAMe and CDP-choline. Journal of neuroscience research, 1982, Volume: 7, Issue:3 Topics: Acetylcholinesterase; Animals; Cerebral Cortex; Choline; Citrate (si)-Synthase; Cytidine Diphosphate Choline; Electron Transport Complex IV; Female; Malate Dehydrogenase; Mitochondria; NADH Dehydrogenase; Rats; S-Adenosylmethionine; Synaptosomes	1982
[Effect of the administration of nucleotide coenzymes on the lipogenic enzyme changes caused by chronic alcohol intoxication]. Revista espanola de fisiologia, 1982, Volume: 38 Suppl Topics: Alcohol Oxidoreductases; Alcoholism; Animals; Choline; Coenzyme A; Cytidine Diphosphate Choline; Dietary Fats; Humans; Lipid Metabolism; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars	1982
Decreased levels of S-adenosylmethionine in the livers of rats fed phenobarbital and DDT. Carcinogenesis, 1982, Volume: 3, Issue:5 Topics: Animals; Body Weight; Choline; DDT; Diet; Eating; Liver; Male; Methionine; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; S-Adenosylmethionine	1982
Role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholine by hepatocytes isolated from choline-deficient rats. FEBS letters, 1982, Aug-23, Volume: 145, Issue:2 Topics: Animals; Choline; Choline Deficiency; In Vitro Techniques; Lipoproteins; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Triglycerides	1982
Alteration in the phosphatidylcholine biosynthesis of rat liver microsomes caused by vitamin B6 deficiency. Bioscience, biotechnology, and biochemistry, 1995, Volume: 59, Issue:2 Topics: Animals; Caseins; Choline; Choline Kinase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diacylglycerol Cholinephosphotransferase; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 6 Deficiency	1995
In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells. Magnetic resonance in medicine, 1994, Volume: 32, Issue:3 Topics: Animals; Carbon Isotopes; Cell Division; Choline; Ethanolamines; Glioma; Magnetic Resonance Spectroscopy; Methionine; Organophosphorus Compounds; Phosphatidylcholines; Phosphatidylserines; Phosphorus Isotopes; Phosphorylcholine; Rats; Rats, Inbred F344; S-Adenosylmethionine; Tumor Cells, Cultured	1994
Evidence that the major membrane lipids, except cholesterol, are made in axons of cultured rat sympathetic neurons. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: Acetates; Acetic Acid; Animals; Axons; Carbon Radioisotopes; Cells, Cultured; Cholesterol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Ethanolamine; Ethanolamines; Inositol; Kinetics; Membrane Lipids; Neurons; Nucleotidyltransferases; Phospholipids; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Serine; Superior Cervical Ganglion; Tritium	1994
Elevation of cerebrospinal fluid choline levels by nicotinamide involves the enzymatic formation of N1-methylnicotinamide in brain tissue. Life sciences, 1996, Volume: 58, Issue:22 Topics: Acetylcholine; Animals; Brain; Choline; Chromatography, High Pressure Liquid; Male; Niacinamide; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Tritium	1996
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:11 Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc	1998
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. Journal of inherited metabolic disease, 1998, Volume: 21, Issue:8 Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates	1998
Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder. Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4 Topics: Adult; Benzophenones; Catechol O-Methyltransferase Inhibitors; Caudate Nucleus; Choline; Depressive Disorder, Major; Female; Frontal Lobe; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nitrophenols; Personality Inventory; Reference Values; S-Adenosylmethionine; Tolcapone; Treatment Outcome	1999
Isolated hypermethioninemia: measurements of S-adenosylmethionine and choline. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:12 Topics: Choline; Humans; Isoenzymes; Methionine; Methionine Adenosyltransferase; Nervous System Diseases; S-Adenosylmethionine	2000
Effect of salt stress on the metabolism of ethanolamine and choline in leaves of the betaine-producing mangrove species Avicennia marina. Phytochemistry, 2003, Volume: 64, Issue:5 Topics: Adaptation, Physiological; Adenosine Kinase; Avicennia; Betaine; Carbon Dioxide; Carbon Radioisotopes; Choline; Ethanolamines; N-Glycosyl Hydrolases; Organophosphorus Compounds; Plant Leaves; S-Adenosylmethionine; Sodium Chloride	2003
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. Brain research. Developmental brain research, 2004, Apr-19, Volume: 149, Issue:2 Topics: Acyltransferases; Animals; Blotting, Western; Brain; Calbindin 2; Choline; Chromatography, High Pressure Liquid; Diet; DNA; Embryo, Mammalian; Female; Gene Deletion; Gene Expression Regulation, Developmental; Hippocampus; Histones; Liver; Male; Methylation; Methyltransferases; Mice; Mice, Knockout; Mitosis; Neurons; Phosphatidylethanolamine N-Methyltransferase; Pregnancy; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; S100 Calcium Binding Protein G; Stem Cells	2004
In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway. The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13 Topics: Amino Acid Sequence; Animals; Base Sequence; Biochemical Phenomena; Biochemistry; Blotting, Western; Choline; Codon; Ethanolamines; Genetic Complementation Test; Genotype; Methyltransferases; Models, Biological; Molecular Sequence Data; Mutation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Plasmodium falciparum; Protein Binding; S-Adenosylmethionine; Saccharomyces cerevisiae; Substrate Specificity; Temperature	2005
Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens. The Journal of nutrition, 2005, Volume: 135, Issue:7 Topics: Animals; Chickens; Choline; Diet; Male; Methionine; S-Adenosylmethionine; Vitamin U	2005
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet. Journal of hepatology, 2006, Volume: 44, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biomarkers; Choline; Chromatography, High Pressure Liquid; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Heterozygote; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Severity of Illness Index; Up-Regulation	2006
Glutathione-enhancing agents protect against steatohepatitis in a dietary model. Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:1 Topics: Animals; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Food, Formulated; Inflammation; Lipotropic Agents; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Thiazoles; Transaminases	2006
S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. Journal of inherited metabolic disease, 2006, Volume: 29, Issue:4 Topics: Adenosylhomocysteinase; Adult; Choline; DNA Methylation; Erythrocytes; Family Health; Humans; Magnetic Resonance Imaging; Male; Metabolism, Inborn Errors; Muscular Diseases; Mutation, Missense; S-Adenosylhomocysteine; S-Adenosylmethionine	2006
Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation. Molecular and cellular biochemistry, 2007, Volume: 294, Issue:1-2 Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; S-Adenosylmethionine	2007
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Digestive diseases and sciences, 2008, Volume: 53, Issue:10 Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated; Glutathione; Hepatitis; Homeostasis; Lipid Metabolism; Liver; Methionine; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; S-Adenosylmethionine	2008
Reduced brain choline in homocystinuria due to remethylation defects. Neurology, 2008, Jul-01, Volume: 71, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Chemistry; Child; Child, Preschool; Choline; Choline Deficiency; Creatine; Female; Homocysteine S-Methyltransferase; Homocystinuria; Humans; Magnetic Resonance Spectroscopy; Male; Methylation; S-Adenosylmethionine	2008
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications. Chemico-biological interactions, 2010, Feb-12, Volume: 183, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gamma Rays; Homocysteine; Male; Mice; S-Adenosylmethionine; Time Factors	2010
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. The Journal of biological chemistry, 2010, Jun-11, Volume: 285, Issue:24 Topics: Animal Feed; Animals; Ceramides; Choline; Fatty Liver; Glutathione; Inflammation; Lipids; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Prodrugs; S-Adenosylmethionine; Sphingomyelin Phosphodiesterase	2010
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats. Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:7 Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine	2010
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. The Journal of biological chemistry, 2011, Oct-21, Volume: 286, Issue:42 Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Carcinoma, Hepatocellular; Choline; Fatty Liver; Gene Deletion; Humans; Lipoproteins, VLDL; Mice; Mice, Knockout; Neoplasm Proteins; Phospholipids; S-Adenosylmethionine; Triglycerides	2011
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model. Molecular nutrition & food research, 2012, Volume: 56, Issue:10 Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult	2012
Methyl group balance in brain and liver: role of choline on increased S-adenosyl methionine (SAM) demand by chronic arsenic exposure. Toxicology letters, 2012, Nov-30, Volume: 215, Issue:2 Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Choline; Female; Immunohistochemistry; Liver; Male; Methylation; Phosphatidylcholines; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Triglycerides	2012
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers. Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3 Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult	2013
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen	2013
The beneficial effect of folate-enriched egg on the folate and homocysteine levels in rats fed a folate- and choline-deficient diet. Journal of food science, 2012, Volume: 77, Issue:12 Topics: Animal Feed; Animals; Choline; Diet; Egg Yolk; Folic Acid; Food, Fortified; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine	2012
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. The American journal of clinical nutrition, 2013, Volume: 97, Issue:6 Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult	2013
Methylation metabolites in amniotic fluid depend on gestational age. Prenatal diagnosis, 2013, Volume: 33, Issue:9 Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine	2013
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads. International journal of food sciences and nutrition, 2014, Volume: 65, Issue:6 Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult	2014
Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism. The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:4 Topics: Animals; Carbon; Carnitine O-Palmitoyltransferase; Cholesterol; Choline; Choline Deficiency; Creatine; Diet; Dietary Supplements; Fatty Liver; Ion Channels; Lipid Metabolism; Liver; Male; Malondialdehyde; Mitochondrial Proteins; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; S-Adenosylmethionine; Triglycerides; Uncoupling Protein 2	2015
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism. The American journal of clinical nutrition, 2016, Volume: 103, Issue:3 Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors	2016
Effects of Nonpurified and Choline Supplemented or Nonsupplemented Purified Diets on Hepatic Steatosis and Methionine Metabolism in C3H Mice. Metabolic syndrome and related disorders, 2016, Volume: 14, Issue:4 Topics: Animals; Choline; Diet; Dietary Fats; Dietary Sucrose; Dietary Supplements; Fatty Liver; Feeding Behavior; Female; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine	2016
Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development. The American journal of clinical nutrition, 2016, Volume: 104, Issue:5 Topics: Aminohydrolases; Animals; Choline; Dietary Supplements; Embryo, Mammalian; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Logistic Models; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Multienzyme Complexes; Placenta; Polymorphism, Single Nucleotide; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine	2016
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model. Biochimie, 2018, Volume: 152 Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine	2018
Purification and Characterization of the Choline Trimethylamine-Lyase (CutC)-Activating Protein CutD. Methods in enzymology, 2018, Volume: 606 Topics: Adaptor Proteins, Signal Transducing; Bacterial Proteins; Choline; Cloning, Molecular; Desulfovibrio; Electron Spin Resonance Spectroscopy; Enzyme Assays; Lyases; Methylamines; Protein Processing, Post-Translational; Recombinant Proteins; S-Adenosylmethionine	2018
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency. Molecular neurobiology, 2019, Volume: 56, Issue:6 Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission	2019
Nutritional characterization of sake cake (sake-kasu) after heat-drying and freeze-drying. Bioscience, biotechnology, and biochemistry, 2019, Volume: 83, Issue:8 Topics: Aspergillus oryzae; beta-Glucans; Betaine; Carbohydrate Metabolism; Choline; Food Handling; Freeze Drying; Fungal Proteins; Hot Temperature; Lipid Metabolism; Niacin; Nucleic Acids; Nutritive Value; Oryza; S-Adenosylmethionine; Saccharomyces cerevisiae; Vitamin B 6	2019
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease. European journal of pharmacology, 2019, Mar-15, Volume: 847 Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine	2019
GlmS mediated knock-down of a phospholipase expedite alternate pathway to generate phosphocholine required for phosphatidylcholine synthesis in Plasmodium falciparum. The Biochemical journal, 2021, 09-30, Volume: 478, Issue:18 Topics: Carboxy-Lyases; Choline; Erythrocytes; Gene Expression Regulation; Gene Knockdown Techniques; Genes, Reporter; Green Fluorescent Proteins; Homeostasis; Humans; Life Cycle Stages; Lipid Metabolism; Lysophosphatidylcholines; Lysophospholipase; Methyltransferases; Phosphatidylcholines; Phosphorylcholine; Plasmodium falciparum; Protozoan Proteins; S-Adenosylmethionine; Serine	2021
Maternal and neonatal one-carbon metabolites and the epigenome-wide infant response. The Journal of nutritional biochemistry, 2022, Volume: 101 Topics: Adult; Betaine; Carbon; Choline; Cohort Studies; DNA Methylation; Epigenome; Female; Fetal Blood; Histone Code; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Metabolomics; Methionine; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine	2022
Prenatal Choline Supplementation Alters One Carbon Metabolites in a Rat Model of Periconceptional Alcohol Exposure. Nutrients, 2022, Apr-29, Volume: 14, Issue:9 Topics: Animals; Carbon; Choline; Dietary Supplements; Ethanol; Female; Humans; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Vitamins	2022
One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme transcript abundance in a dose-dependent manner. Journal of animal science, 2023, Jan-03, Volume: 101 Topics: Animals; Carbon; Cattle; Choline; Dietary Supplements; Estrous Cycle; Female; Folic Acid; Liver; Methionine; Racemethionine; Rumen; S-Adenosylmethionine	2023
Functional analysis of phosphoethanolamine N-methyltransferase in plants and parasites: Essential S-adenosylmethionine-dependent methyltransferase in choline and phospholipid metabolism. Methods in enzymology, 2023, Volume: 680 Topics: Animals; Choline; Humans; Methyltransferases; Parasites; Phospholipids; Phylogeny; S-Adenosylmethionine	2023
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups. Cell reports, 2023, 02-28, Volume: 42, Issue:2 Topics: Animals; Choline; Glycerylphosphorylcholine; Liver; Lysophospholipase; Methionine; Mice; Phosphatidylcholines; Racemethionine; S-Adenosylmethionine; Triglycerides	2023
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation. Nutrients, 2023, Aug-17, Volume: 15, Issue:16 Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements	2023