choline has been researched along with piperidines in 100 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (38.00) | 18.7374 |
| 1990's | 28 (28.00) | 18.2507 |
| 2000's | 22 (22.00) | 29.6817 |
| 2010's | 11 (11.00) | 24.3611 |
| 2020's | 1 (1.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knowles, PF; Marsh, D; Watts, A | 1 |
| Maeda, T; Ohnishi, SI; Yanagida, M | 1 |
| Ichiki, T; Setaka, M; Shimizu, H | 1 |
| Iarv, IaL; Kesvatera, TA; Rozengart, EV | 1 |
| Gerlach, J | 1 |
| Wagner, G; Walczok, A; Wessler, I | 1 |
| Badini, I; Beani, L; Bianchi, C; Cintra, A; Fuxe, K; Siniscalchi, A | 1 |
| Collier, B; Gomez, MV; Prado, MA | 1 |
| Van der Kloot, W; Yu, SP | 1 |
| Long, JP; Sheff, KY; Yorek, MA | 3 |
| Kang, YS; Ohnishi, T; Terasaki, T; Tsuji, A | 1 |
| Gildersleeve, DL; Jung, YW; Van Dort, ME; Wieland, DM | 1 |
| Diebler, MF; Gaudry-Talarmain, YM; O'Regan, S | 1 |
| Mingard, F; Montrose-Rafizadeh, C; Murer, H; Roch-Ramel, F | 1 |
| Vizi, ES | 1 |
| Collier, B; Mykita, S | 1 |
| Suszkiw, JB; Toth, G | 1 |
| Bhatnagar, RK; Cannon, JG; Flynn, JR; Long, JP; Tedford, CE | 1 |
| Cannon, JG; Flynn, JR; Long, JP; Sheff, KY; Tedford, CE; Yorek, MA | 1 |
| Bhatnagar, R; Cannon, JG; Chatterjee, T; Long, JP; Sheff, K; Tedford, CE; Wang, YF | 1 |
| Cabeza, R; Collier, B | 1 |
| Bhatnagar, RK; Cannon, JG; Chatterjee, TK; Long, JP | 1 |
| Carroll, PT; Ivy, MT | 1 |
| Bahr, BA; Parsons, SM | 1 |
| Collins, RC; Olney, JW; Sloviter, RS | 1 |
| Johnson, GV; Jope, RS | 1 |
| Collier, B; Welner, SA | 1 |
| Meyer, EM; Otero, DH; Wilbekin, F | 1 |
| Christensen, HN; De Cespedes, C; Handlogten, ME; Ronquist, G | 1 |
| Domer, FR; Hiatt, RA | 1 |
| Brittain, RT; Levy, GP; Tyers, MB | 1 |
| McConnell, HM; McNamee, MG | 1 |
| Marshall, IG | 2 |
| Borg, KO; Holgersson, H; Lagerström, PO | 1 |
| Ekström, J | 1 |
| Jewers, K; McLean, WF | 1 |
| Gandiha, A; Marshall, IG | 1 |
| Thron, CD; Waud, DR | 1 |
| Contestabile, A; Migani, P; Poli, A; Villani, L | 1 |
| Aracava, Y; Deslauriers, R; Phadke, R; Schreier, S; Smith, IC | 1 |
| Kuroda, K; Maeda, T; Ohnishi, S; Toyama, S | 1 |
| Hemsworth, BA; Shreeve, SM; Veitch, GB | 1 |
| Adelung, C; Lang, JD; Späth, L; Starke, K | 1 |
| Bartosz, G; Gwoździński, K; Leyko, W | 1 |
| Cooke, HJ; Javed, N; Reddix, R; Wang, YZ | 1 |
| Gebauer, A; Haas, J; Kilbinger, H; Ladinsky, H; Rizzi, CA | 1 |
| Dietrich, C; Kilbinger, H | 1 |
| Diebler, MF; Meunier, FM; O'Regan, S; Vyas, S | 1 |
| Bobbin, RP; Erostegui, C; Norris, CH | 1 |
| Abdel-Ghany, Y; Kunin, CM; LeRudulier, D; Miller, DD; Poggi, MC; Tong, HH | 1 |
| Suidan, HS; Tolkovsky, AM | 1 |
| Efange, SM; Khare, AB; Michelson, RH; Thomas, JR | 1 |
| Nakamura, S; Ohno, T | 1 |
| Bonanno, G; Fassio, A; Fontana, G; Marchi, M; Raiteri, M; Usai, C | 1 |
| Balezina, OP; Naves, LA; Van der Kloot, W | 1 |
| Naves, LA; Van der Kloot, W | 1 |
| Davison, JS; Jennings, LJ; Pariente, JA; Salido, GM; Sharkey, KA; Singh, J | 1 |
| Fitzgerald, RS; Ishizawa, Y; Shirahata, M | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K | 1 |
| Kobayashi, H; Saitoh, S; Suzuki, T; Takeno, K; Watanabe, T; Yasufuku, T | 1 |
| Cheng, DH; Tang, XC | 1 |
| Eaton, BM; Sooranna, SR | 1 |
| Lu, Y; Shi, H; Wang, H; Wang, Z; Yang, B | 1 |
| Auld, DS; Day, JC; Mennicken, F; Quirion, R | 2 |
| Gustafsson, LE; Olgart, C; Wiklund, NP | 1 |
| D'Agostino, G; Erbelding, D; Kilbinger, H | 1 |
| Kathmann, M; Schlicker, E; Weber, B | 1 |
| Carroll, PT; Roghani, A | 1 |
| Chen, QW; Li, HW; Liu, Y; Ma, ML; Wang, Y; Yang, BF; Zhang, Y | 1 |
| Feuerstein, TJ; Klar, M; Rominger, A; Steffens, M; Szabo, B; Zentner, J | 1 |
| Jin, H; Kopke, RD; Sha, D; Wu, JY | 1 |
| Jing, YH; Li, HL; Liu, Y; Sun, HL; Yang, BF | 1 |
| Bravo, DT; Kolmakova, NG; Parsons, SM | 1 |
| Dong, DL; Jiao, JD; Liu, Y; Wang, HZ; Xu, CQ; Yang, BF | 1 |
| Kang, YS; Lee, KE; Lee, NY; Terasaki, T | 1 |
| Küçükkilinç, T; Ozer, I | 1 |
| Kusumoto, H; Minami, A; Shimazu, S; Takahata, K; Yoneda, F | 1 |
| Bartha, R; Borrie, MJ; Rupsingh, R; Rylett, J; Smith, M; Wells, JL | 1 |
| Shimohama, S | 1 |
| Cheng, K; Davis, RJ; Drachenberg, C; Nomikos, G; Raufman, JP; Samimi, R; Shant, J; Wade, M; Xie, G | 1 |
| Pan, GP; Sun, LH; Wang, L; Yang, BF; Zhang, GX; Zhang, YL | 1 |
| Du, ZM; Gao, Y; Li, DL; Liu, Y; Lu, YJ; Sun, HL; Wang, LY; Wang, YP; Yang, BF | 1 |
| Kesler, SR; Lightbody, AA; Reiss, AL | 1 |
| Oberg, J; Pahnke, J; Reyer, H; Spenger, C; Wahlund, LO; Westman, E | 1 |
| Chung, SJ; Kim, DD; Kim, MH; Lee, KR; Maeng, HJ; Shim, CK; Tsuruo, T; Yu, KH | 1 |
| Chonpathompikunlert, P; Muchimapura, S; Wattanathorn, J | 1 |
| Ikarashi, Y; Imamura, S; Kanno, H; Kase, Y; Sekiguchi, K; Tabuchi, M; Terawaki, K; Yamaguchi, T | 1 |
| Colburn, NH; Farrar, W; Kim, YS; Milner, JA | 1 |
| Bessaire, T; Delatour, T; Stadler, RH; Tarres, A | 1 |
| Altinbas, B; Jochem, J; Savci, V; Yalcin, M; Yilmaz, MS | 1 |
| Bi, XY; He, X; Lu, XZ; Xu, M; Yu, XJ; Zang, WJ; Zhao, M; Zhao, ZH | 1 |
| Acevedo, AC; Chardin, H; De Luca Canto, G; Gozal, D; Guerra, EN; Leite, AF | 1 |
| Hopfeld, J; Klein, J; Lau, H; Stein, C | 1 |
| Alves, G; Falcao, A; Matias, M; Silvestre, S | 1 |
| Li, L; Ning, Q; Wang, H; Wang, X; Xiao, F | 1 |
| Duan, M; Han, S; Hu, L; Li, M; Ma, L; Rao, MJ; Tahir Ul Qamar, M; Wang, L; Wei, X; Zuo, H | 1 |
5 review(s) available for choline and piperidines
| Article | Year |
|---|---|
Recent advances in the use of selective neuron-destroying agents for neurobiological research.
Topics: Animals; Aziridines; Choline; Colchicine; Folic Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Lectins; Mitogens; Mustard Compounds; Nerve Degeneration; Nervous System; Neurons; Piperidines; Pyrrolidonecarboxylic Acid; Quinolinic Acid; Quinolinic Acids | 1984 |
[Treatment of Alzheimer's disease: status quo and future considerations].
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Behavioral Symptoms; Choline; Cholinesterase Inhibitors; Cognition; Donepezil; Drug Design; Galantamine; Glutamic Acid; Humans; Indans; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Risk Factors; Rivastigmine | 2008 |
Cancer stem cells: potential target for bioactive food components.
Topics: Alkaloids; Benzodioxoles; Catechin; Cell Differentiation; Cell Proliferation; Choline; Curcumin; Cyclin-Dependent Kinase 6; Diet; Epigenesis, Genetic; Gene Expression Regulation; Genistein; Glutamates; Humans; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Membrane Proteins; Mesenchymal Stem Cells; Neoplastic Stem Cells; Nuclear Proteins; Piperidines; Plant Extracts; Polycomb Repressive Complex 1; Polyunsaturated Alkamides; Proto-Oncogene Proteins; Repressor Proteins; STAT1 Transcription Factor; Sulfoxides; Thiocyanates; Vitamin A; Vitamin D; Wnt Proteins | 2012 |
Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carbocysteine; Choline; Head and Neck Neoplasms; Humans; Interleukin-8; Middle Aged; Phenylalanine; Piperidines; Saliva; Sensitivity and Specificity; Young Adult | 2015 |
Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders.
Topics: Analgesics; Central Nervous System Diseases; Choline; Donepezil; Epilepsy; gamma-Aminobutyric Acid; Humans; Indans; Opioid Peptides; Pain; Piperidines; Tacrine | 2017 |
2 trial(s) available for choline and piperidines
| Article | Year |
|---|---|
High field (1)H MRS of the hippocampus after donepezil treatment in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain Chemistry; Choline; Cholinesterase Inhibitors; Creatine; Donepezil; Female; Hippocampus; Humans; Indans; Inositol; Magnetic Resonance Spectroscopy; Male; Piperidines; Protons | 2008 |
Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary 1H MRS study.
Topics: Adolescent; Adult; Case-Control Studies; Choline; Cholinesterase Inhibitors; Cognition; Creatine; Donepezil; Dose-Response Relationship, Drug; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Indans; Intelligence; Male; Nuclear Magnetic Resonance, Biomolecular; Pilot Projects; Piperidines; Prefrontal Cortex; Prospective Studies; Radiography; Time Factors; Treatment Outcome; Young Adult | 2009 |
93 other study(ies) available for choline and piperidines
| Article | Year |
|---|---|
Evidence for phase boundary lipid. Permeability of Tempo-choline into dimyristoylphosphatidylcholine vesicles at the phase transition.
Topics: Binding Sites; Biological Transport; Choline; Electron Spin Resonance Spectroscopy; Kinetics; Mathematics; Membranes, Artificial; Models, Biological; Molecular Conformation; Myristic Acids; Permeability; Phosphatidylcholines; Piperidines; Temperature; Thermodynamics | 1976 |
Infection-triggered release of tempocholine from bacteriophage G4 studied by electron spin resonance.
Topics: Choline; Coliphages; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Escherichia coli; Kinetics; Piperidines; Spin Labels; Virus Replication | 1978 |
Asymmetric permeability of the membrane of egg phosphatidylcholine-cholesterol vesicles to 2,2,6,6 tetramethyl piperidinyl-l-oxycholine.
Topics: Cholesterol; Choline; Electron Spin Resonance Spectroscopy; Liposomes; Permeability; Phosphatidylcholines; Piperidines; Spin Labels; Surface Properties; Temperature | 1978 |
[Inhibition of acetylcholinesterase hydrolysis of cationic substrates by the reaction product].
Topics: Acetylcholine; Binding Sites; Choline; Cholinesterase Inhibitors; Hydrolysis; Kinetics; Piperidines | 1978 |
The relationship between parkinsonism and tardive dyskinesia.
Topics: Age Factors; Aminobutyrates; Baclofen; Basal Ganglia; Biperiden; Choline; Dopamine; Dyskinesia, Drug-Induced; Humans; Levodopa; Methyltyrosines; Mouth; Parkinson Disease; Piperidines; Tranquilizing Agents | 1977 |
Suppression by cholinesterase inhibition of a Ca(2+)-independent efflux of [3H]acetylcholine from the neuromuscular junction of the isolated rat diaphragm.
Topics: Acetylcholine; Animals; Calcium; Choline; Cholinesterase Inhibitors; Diaphragm; Female; In Vitro Techniques; Male; Neuromuscular Junction; Physostigmine; Piperidines; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tritium | 1992 |
Muscarinic modulation of acetylcholine release from slices of guinea pig nucleus basalis magnocellularis.
Topics: Acetylcholine; Animals; Atropine; Calcium; Choline; Female; Guinea Pigs; Male; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Receptors, Muscarinic; Substantia Innominata; Tetrodotoxin | 1992 |
Mobilization of the readily releasable pool of acetylcholine from a sympathetic ganglion by tityustoxin in the presence of vesamicol.
Topics: Acetylcholine; Animals; Cats; Choline; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Neuromuscular Depolarizing Agents; Piperidines; Scorpion Venoms; Tritium | 1992 |
Increasing quantal size at the mouse neuromuscular junction and the role of choline.
Topics: Acetylcholine; Animals; Anura; Choline; Curare; Electric Stimulation; Female; Hormones; Hypertonic Solutions; In Vitro Techniques; Kinetics; Male; Mice; Models, Neurological; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Piperidines; Sodium; Species Specificity; Synapses | 1991 |
Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells.
Topics: Animals; Biphenyl Compounds; Choline; Ethanolamine; Ethanolamines; Mice; Neuroblastoma; Phosphatidylcholines; Phospholipids; Piperidines; S-Adenosylmethionine; Tumor Cells, Cultured | 1991 |
Hemicholinium-3 derivatives A-4 and A-5 affect choline and acetylcholine metabolism.
Topics: Acetylcholine; Animals; Biological Transport, Active; Biphenyl Compounds; Choline; Hemicholinium 3; Neurons; Parasympatholytics; Piperidines; Tumor Cells, Cultured | 1991 |
Characterization of the effect of two 4-methyl piperidine derivatives of hemicholinium-3, A-4 and A-5, on choline transport.
Topics: Animals; Biological Transport; Biphenyl Compounds; Choline; Dose-Response Relationship, Drug; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Sodium; Tumor Cells, Cultured | 1990 |
In vivo and in vitro evidence for a common carrier mediated transport of choline and basic drugs through the blood-brain barrier.
Topics: Animals; Biological Transport; Biphenyl Compounds; Blood-Brain Barrier; Capillaries; Choline; Drug Carriers; Isoproterenol; Kinetics; Male; Parasympatholytics; Piperidines; Propiophenones; Rats; Scopolamine; Thiamine; Tritium | 1990 |
A radiotracer for mapping cholinergic neurons of the brain.
Topics: Acetylcholine; Animals; Brain; Cerebellum; Cerebral Cortex; Choline; Corpus Striatum; Female; Iodine Radioisotopes; Kinetics; Mice; Molecular Structure; Neurons; Phencyclidine; Piperidines; Stereoisomerism; Tetrahydronaphthalenes; Tritium | 1990 |
Compared effects of two vesicular acetylcholine uptake blockers, AH5183 and cetiedil, on cholinergic functions in Torpedo synaptosomes: acetylcholine synthesis, choline transport, vesicular uptake, and evoked acetylcholine release.
Topics: Acetylcholine; Animals; Azepines; Biological Transport; Calcimycin; Choline; Electric Organ; Hydrogen-Ion Concentration; Kinetics; Neuromuscular Depolarizing Agents; Phencyclidine; Piperidines; Synaptic Vesicles; Synaptosomes; Torpedo | 1989 |
Carrier-mediated transport of tetraethylammonium across rabbit renal basolateral membrane.
Topics: Acridine Orange; Amiloride; Animals; Biological Transport; Cell Membrane; Choline; Female; Ganglionic Blockers; Kidney Cortex; Kinetics; Male; Monensin; Morphine; Piperidines; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
In favour of the vesicular hypothesis: neurochemical evidence that vesamicol (AH5183) inhibits stimulation-evoked release of acetylcholine from neuromuscular junction.
Topics: Acetylcholine; Animals; Calcium; Choline; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Phencyclidine; Phrenic Nerve; Piperidines | 1989 |
Acetylcholine synthesis by a sympathetic ganglion in the presence of 2-(4-phenylpiperidino)cyclohexanol (AH5183) and picrylsulfonic acid.
Topics: Acetylcholine; Animals; Cats; Choline; Drug Combinations; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Neuromuscular Depolarizing Agents; Nitrobenzenes; Osmolar Concentration; Phencyclidine; Piperidines; Trinitrobenzenesulfonic Acid | 1989 |
Storage and release of acetylcholine in rat cortical synaptosomes: effects of D,L-2-(4-phenylpiperidino)cyclohexanol (AH5183).
Topics: Acetylcholine; Animals; Calcium; Cerebral Cortex; Choline; Cholinergic Fibers; Phencyclidine; Piperidines; Potassium; Rats; Synaptic Transmission; Synaptosomes | 1986 |
Alterations in acetylcholine metabolism in rat striatal slices by a 4-methyl piperidine analog of hemicholinium-3.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Choline; Chromatography, High Pressure Liquid; Corpus Striatum; Hemicholinium 3; Piperidines; Potassium; Rats; Structure-Activity Relationship | 1988 |
Stereoisomers of quaternary and tertiary 4-methyl piperidine analogs of hemicholinium-3.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Caudate Nucleus; Cells, Cultured; Choline; Hemicholinium 3; Male; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Sciatic Nerve; Stereoisomerism | 1988 |
Optical isomers of some piperidine-derived hemicholinium congeners containing secondary alcohol groups: preparation and biological activities.
Topics: Alcohols; Animals; Caudate Nucleus; Chemical Phenomena; Chemistry; Choline; Hemicholinium 3; In Vitro Techniques; Male; Neuromuscular Junction; Piperidines; Rabbits; Rats; Stereoisomerism; Synaptosomes | 1988 |
Acetylcholine mobilization in a sympathetic ganglion in the presence and absence of 2-(4-phenylpiperidino)cyclohexanol (AH5183).
Topics: Acetylcholine; Animals; Black Widow Spider; Cats; Choline; Electric Stimulation; Female; Ganglia, Sympathetic; Kinetics; Male; Neuromuscular Depolarizing Agents; Phencyclidine; Piperidines; Spider Venoms; Tritium | 1988 |
Methylpiperidine analog of hemicholinium-3: a selective, high affinity non-competitive inhibitor of sodium dependent choline uptake system.
Topics: Animals; Choline; Corpus Striatum; Hemicholinium 3; In Vitro Techniques; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains; Sodium; Synaptosomes | 1988 |
Effect of 2-(4-phenylpiperidino)cyclohexanol (AH 5183) on the veratridine-induced increase in acetylcholine synthesis by rat hippocampal tissue.
Topics: Acetylcholine; Animals; Choline; Choline O-Acetyltransferase; Hippocampus; Isotonic Solutions; L-Lactate Dehydrogenase; Male; Naphthylvinylpyridine; Octoxynol; Phencyclidine; Piperidines; Polyethylene Glycols; Rats; Rats, Inbred Strains; Solubility; Subcellular Fractions; Veratridine; Veratrine | 1988 |
Demonstration of a receptor in Torpedo synaptic vesicles for the acetylcholine storage blocker L-trans-2-(4-phenyl[3,4-3H]-piperidino) cyclohexanol.
Topics: Acetylcholine; Animals; Binding, Competitive; Choline; Electric Organ; Kinetics; Phencyclidine; Piperidines; Receptors, Drug; Stereoisomerism; Synaptic Vesicles; Torpedo | 1986 |
Excitotoxic mechanisms of epileptic brain damage.
Topics: Administration, Topical; Amygdala; Animals; Axons; Biomechanical Phenomena; Brain; Choline; Cholinesterase Inhibitors; Convulsants; Corpus Striatum; Epilepsy; Folic Acid; Injections; Kainic Acid; Lithium; Motor Cortex; Neural Pathways; Neurotoxins; Piperidines; Rats; Seizures; Somatosensory Cortex | 1986 |
Quinacrine and 2-(4-phenylpiperidino)cyclohexanol (AH5183) inhibit acetylcholine release and synthesis in rat brain slices.
Topics: Acetylcholine; Animals; Biological Transport; Brain; Choline; In Vitro Techniques; Kinetics; Male; Neuromuscular Depolarizing Agents; Phencyclidine; Piperidines; Potassium; Quinacrine; Rats; Rats, Inbred Strains | 1986 |
Accumulation, acetylation, and releasability of diethylhomocholine from a sympathetic ganglion.
Topics: Acetylation; Acetylcholine; Animals; Calcium; Cats; Choline; Electric Stimulation; Female; Ganglia, Sympathetic; Magnesium; Male; Neuromuscular Depolarizing Agents; Phencyclidine; Physostigmine; Piperidines | 1985 |
Effects of 4-(2-hydroxyethyl)-1-piperazine-ethanesulfonic acid (AH5183) on rat cortical synaptosome choline uptake, acetylcholine storage and release.
Topics: Acetylcholine; Animals; Cerebral Cortex; Choline; In Vitro Techniques; Male; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Modified transport substrates as probes for intramembrane gradients.
Topics: Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Cell Membrane; Choline; Dinitrophenols; Gramicidin; Kinetics; Lysine; Membrane Potentials; Methods; Mice; Models, Biological; Piperidines; Sodium; Time Factors | 1974 |
Effects of quaternary ammonium compounds on the movement of potassium out of the cerebrospinal fluid.
Topics: Animals; Biological Transport; Cats; Choline; Decamethonium Compounds; Female; Hexamethonium Compounds; Male; Muscle Contraction; Neostigmine; Niacinamide; Perfusion; Piperidines; Potassium; Potassium Isotopes; Quaternary Ammonium Compounds; Succinylcholine; Tetraethylammonium Compounds; Tubocurarine | 1968 |
The neuromuscular blocking action of 2-(4-phenylpiperidino) cyclohexanol (AH 5183).
Topics: Animals; Atropine; Cats; Chickens; Choline; Cyclohexanes; Diaphragm; Electric Stimulation; Guinea Pigs; Ileum; Injections, Intravenous; Male; Mice; Muscle Contraction; Muscles; Neuromuscular Nondepolarizing Agents; Phrenic Nerve; Physostigmine; Piperidines; Rats; Tibia; Tubocurarine | 1969 |
Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles.
Topics: Animals; Ascorbic Acid; Biological Transport; Cell Membrane; Centrifugation, Density Gradient; Choline; Cyclic N-Oxides; Electric Organ; Electron Spin Resonance Spectroscopy; Fishes; Kinetics; Membrane Potentials; Organoids; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Piperidines; Sodium; Sodium Isotopes; Time Factors | 1973 |
Studies on the blocking action of 2-(4-phenyl piperidino) cyclohexanol (AH5183).
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cats; Chickens; Choline; Cyclohexanes; Diaphragm; Ear, External; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Neostigmine; Neuromuscular Junction; Phrenic Nerve; Piperidines; Rabbits; Rats; Tetraethylammonium Compounds | 1970 |
Determination of piribenzil in urine containing a metabolite and dextropropoxyphene by an ion pair extraction method.
Topics: Benzilates; Choline; Dextropropoxyphene; Humans; Methods; Nicotine; Parasympatholytics; Photometry; Piperidines; Quaternary Ammonium Compounds; Solubility; Tryptamines; Tyramine | 1970 |
A comparison between the blocking actions of 2-(4-phenylpiperidino) cyclohexanol (AH 5183) and its N-methyl quaternary analogue (AH 5954).
Topics: Adrenergic alpha-Antagonists; Alcohols; Anesthesia, Local; Animals; Cats; Chickens; Choline; Cyclohexanes; Electric Stimulation; Hypersensitivity; In Vitro Techniques; Muscles; Neostigmine; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Piperidines; Quaternary Ammonium Compounds; Rabbits; Rats; Tetraethylammonium Compounds | 1970 |
Choline acetyltransferase activity in rat salivary glands after cellulose rich diet or treatment with an atropine-like drug.
Topics: Acetyltransferases; Amides; Animals; Atropine; Cellulose; Choline; Diet; Parasympatholytics; Parotid Gland; Piperidines; Rats | 1974 |
Thin-layer chromatography of quaternary ammonium salts on alumina layers.
Topics: Acetylcholine; Betaine; Carnitine; Choline; Chromatography, Thin Layer; Hexamethonium Compounds; Methods; Piperidines; Pyridinium Compounds; Pyrrolidines; Quaternary Ammonium Compounds; Tetraethylammonium Compounds | 1972 |
Studies on the action of some cholinoceptor agonists on the chick biventer cervicis muscle preparation.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Choline; Cyclohexanols; Decamethonium Compounds; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Electric Stimulation; Ganglionic Stimulants; In Vitro Techniques; Muscle Contraction; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Nicotine; Parasympathomimetics; Physostigmine; Piperidines; Quaternary Ammonium Compounds | 1973 |
The rate of action of atropine.
Topics: Animals; Atropine; Carbachol; Choline; Dibenzylchlorethamine; Guinea Pigs; Heart; Heart Atria; Hexamethonium Compounds; Ileum; In Vitro Techniques; Kinetics; Models, Biological; Perfusion; Physostigmine; Piperidines; Receptors, Drug; Reserpine | 1968 |
Spin label reduction kinetics, a procedure to study the effect of drugs on membrane permeability: the effects of monosodium urate, dimethyl sulfoxide and amphotericin B.
Topics: Amphotericin B; Ascorbic Acid; Cell Membrane Permeability; Cholesterol; Choline; Cyclic N-Oxides; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Kinetics; Liposomes; Oxidation-Reduction; Piperidines; Spin Labels; Uric Acid | 1981 |
Interaction of hemagglutinating virus of Japan with erythrocytes as studied by release of a spin probe from virus.
Topics: Choline; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Hot Temperature; Humans; In Vitro Techniques; Parainfluenza Virus 1, Human; Piperidines; Spin Labels | 1981 |
Pharmacological actions of some cyclic analogues of choline.
Topics: Abdominal Muscles; Acetylcholine; Animals; Biological Transport, Active; Brain; Chemical Phenomena; Chemistry; Choline; Cholinesterase Inhibitors; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Phrenic Nerve; Piperidines; Ranidae; Rats; Synaptic Transmission; Synaptosomes | 1984 |
Further functional in vitro comparison of pre- and postsynaptic dopamine receptors in the rabbit caudate nucleus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Apomorphine; Benzazepines; Caudate Nucleus; Choline; Clonidine; Female; Male; Piperidines; Rabbits; Receptors, Dopamine | 1983 |
Effect of gamma radiation on the transport of spin-labeled compounds across the erythrocyte membrane.
Topics: Animals; Biological Transport; Cattle; Choline; Cyclic N-Oxides; Dose-Response Relationship, Radiation; Erythrocyte Membrane; Erythrocytes; Extracellular Space; Gamma Rays; Kinetics; Mathematics; Piperidines; Spin Labels | 1981 |
Cholinergic and VIP-ergic pathways mediate histamine H2 receptor-induced cyclical secretion in the guinea pig colon.
Topics: Acetylcholine; Amiloride; Animals; Atropine; Choline; Colon; Dimaprit; Electric Conductivity; Guinea Pigs; Histamine Release; Intestinal Mucosa; Male; ortho-Aminobenzoates; Piperidines; Pirenzepine; Receptors, Histamine H2; Vasoactive Intestinal Peptide | 1995 |
Benzimidazolones and renzapride facilitate acetylcholine release from guinea-pig myenteric plexus via 5-HT4 receptors.
Topics: Acetylcholine; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Choline; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Myenteric Plexus; Phosphodiesterase Inhibitors; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Prejunctional M1 and postjunctional M3 muscarinic receptors in the circular muscle of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Choline; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
A Ewing's sarcoma cell line showing some, but not all, of the traits of a cholinergic neuron.
Topics: Acetylcholine; Adult; Calcium-Binding Proteins; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Humans; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Neuromuscular Depolarizing Agents; Neurons; Piperidines; Proteolipids; RNA, Messenger; Sarcoma, Ewing; Synaptotagmin I; Synaptotagmins; Tritium; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1995 |
In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Bungarotoxins; Carbachol; Choline; Cholinergic Antagonists; Curare; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Nicotine; Piperidines; Pirenzepine; Quinolizines; Receptors, Cholinergic; Strychnine; Trimethaphan | 1994 |
Effect of novel compound, 1-methyl-1-piperidino methane sulfonate (MPMS), on the osmoprotectant activity of glycine betaine, choline and L-proline in Escherichia coli.
Topics: Azetidinecarboxylic Acid; Betaine; Biological Transport; Choline; Escherichia coli; Mesylates; Piperidines; Proline; Sodium Chloride; Water-Electrolyte Balance | 1993 |
Sympathetic neurons expressing cholinergic properties are poised to allocate choline symmetrically between acetylcholine and the phosphatidylcholine-generating pathway in growing neurites.
Topics: Acetylcholine; Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Choline; Choline O-Acetyltransferase; Ganglia, Sympathetic; Kinetics; Meglumine; Neurites; Neuromuscular Depolarizing Agents; Neurons; Organ Culture Techniques; Phosphatidylcholines; Piperidines; Potassium; Rats; Time Factors; Tritium | 1993 |
Synthesis and tissue distribution of (m-[125I]iodobenzyl)trozamicol ([125I]MIBT): potential radioligand for mapping central cholinergic innervation.
Topics: Animals; Autoradiography; Brain; Cerebellum; Cerebral Cortex; Choline; Corpus Striatum; Iodine Radioisotopes; Iodobenzenes; Isotope Labeling; Kinetics; Male; Molecular Structure; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Tissue Distribution | 1993 |
Spatial learning impairment in aged rats: comparing between aged basal forebrain lesioned and normal aged rats.
Topics: Acetylcholinesterase; Aging; Animals; Aziridines; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Coloring Agents; Kinetics; Male; Maze Learning; Neuromuscular Blocking Agents; Piperidines; Prosencephalon; Rats; Rats, Inbred F344; Space Perception | 1995 |
Role of external and internal calcium on heterocarrier-mediated transmitter release.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Carrier Proteins; Chelating Agents; Choline; Clonidine; Dopamine; Dopamine Agonists; Egtazic Acid; Ergolines; GABA Modulators; Hippocampus; Male; Muscarinic Agonists; Neostriatum; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Norepinephrine; Oxotremorine; Piperidines; Presynaptic Terminals; Quinpirole; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium; Yohimbine | 1996 |
Monoethylcholine as a false transmitter precursor at the frog and mouse neuromuscular junctions.
Topics: Animals; Choline; Cholinesterase Inhibitors; Edrophonium; Electric Stimulation; Hemicholinium 3; Methylamines; Mice; Mice, Inbred Strains; Neostigmine; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Piperidines; Prodrugs; Rana pipiens | 1996 |
Transmitter packaging at frog neuromuscular junctions exposed to anticholinesterases; the role of second-stage acetylcholine loading.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Cholinesterase Inhibitors; Motor Endplate; Neostigmine; Neuromuscular Depolarizing Agents; Piperidines; Rana pipiens | 1996 |
Control of exocrine secretion in the guinea-pig pancreas by histamine H3 receptors.
Topics: alpha-Amylases; Animals; Choline; Electric Stimulation; Female; Guinea Pigs; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Pancreas; Piperidines; Pyrilamine; Receptors, Histamine H3; Tritium | 1996 |
The presynaptic component of a cholinergic mechanism in the carotid body chemotransduction of hypoxia in the cat.
Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Azepines; Carotid Body; Carrier Proteins; Cats; Cell Hypoxia; Choline; Choline O-Acetyltransferase; Enzyme Inhibitors; Glossopharyngeal Nerve; Hemicholinium 3; Hypoxia; Membrane Transport Proteins; Models, Neurological; Naphthylvinylpyridine; Nerve Tissue Proteins; Piperidines; Pyridines; Receptors, Presynaptic; Signal Transduction; Synaptic Vesicles | 1996 |
Effects of thioperamide on the cholinergic system and the step-through passive avoidance test in mice.
Topics: Acetylcholine; Animals; Avoidance Learning; Brain Chemistry; Choline; Histamine Antagonists; Male; Memory; Mice; Mice, Inbred ICR; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Rats; Scopolamine | 1995 |
Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain; Choline; Choline O-Acetyltransferase; Dichlorvos; Injections, Intraperitoneal; Male; Neuromuscular Depolarizing Agents; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Subcellular Fractions | 1997 |
Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities.
Topics: Alkaloids; Animals; Aziridines; Choline; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Dose-Response Relationship, Drug; Female; Indans; Injections, Intraventricular; Male; Maze Learning; Memory; Memory, Short-Term; Neuromuscular Blocking Agents; Piperidines; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tacrine | 1998 |
Regulation of the choline transport system in superfused microcarrier cultures of BeWo cells.
Topics: Bethanechol; Biological Transport; Choline; Choriocarcinoma; Drug Carriers; Female; Hemicholinium 3; Humans; Microvilli; Naphthalenes; Neostigmine; Nicotine; Physostigmine; Piperidines; Quaternary Ammonium Compounds; Trophoblasts; Tumor Cells, Cultured; Uterine Neoplasms | 1998 |
Choline modulates cardiac membrane repolarization by activating an M3 muscarinic receptor and its coupled K+ channel.
Topics: Animals; Choline; Dogs; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Myocardium; Patch-Clamp Techniques; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic | 1999 |
Pharmacological characterization of endogenous acetylcholine release from primary septal cultures.
Topics: Acetylcholine; Animals; Cells, Cultured; Choline; Choline O-Acetyltransferase; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Muscarinic Agonists; Neuromuscular Depolarizing Agents; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Rats; Septum of Brain; Time Factors; Veratridine | 2000 |
Evidence for nonvesicular nitric oxide release evoked by nerve activation.
Topics: Acetylcholine; Animals; Atropine; Botulinum Toxins; Botulinum Toxins, Type A; Choline; Electric Stimulation; Enzyme Inhibitors; Exocytosis; Guinea Pigs; Intestines; Membrane Proteins; Muscle, Smooth; Myenteric Plexus; Nerve Tissue Proteins; Neural Inhibition; Nitric Oxide; Nitroarginine; Parasympatholytics; Piperidines; Quinuclidines; R-SNARE Proteins; Synaptic Transmission; Tetrodotoxin; Tritium | 2000 |
Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea.
Topics: Acetylcholine; Animals; Benzamides; Capsaicin; Choline; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Trachea | 2000 |
Cannabinoid CB1 receptor-mediated inhibition of acetylcholine release in the brain of NMRI, CD-1 and C57BL/6J mice.
Topics: Acetylcholine; Animals; Benzoxazines; Brain; Calcium; Choline; Cyclohexanols; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morpholines; Naphthalenes; Oxotremorine; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tritium | 2001 |
Neurotrophins differentially enhance acetylcholine release, acetylcholine content and choline acetyltransferase activity in basal forebrain neurons.
Topics: Acetylcholine; Animals; Biological Transport; Calcium Channel Blockers; Carrier Proteins; Cells, Cultured; Choline; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Membrane Transport Proteins; Nerve Growth Factors; Neuromuscular Depolarizing Agents; Neurons; Piperidines; Potassium; Prosencephalon; Rats; Rats, Sprague-Dawley; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2001 |
Analysis of uptake and release of newly synthesized acetylcholine in PC12 cells overexpressing the rat vesicular acetylcholine transporter (VAChT).
Topics: Acetates; Acetylcholine; Animals; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Central Nervous System; Choline; Choline O-Acetyltransferase; Clone Cells; Cloning, Molecular; Gene Expression Regulation; Membrane Potentials; Membrane Transport Proteins; Neuromuscular Depolarizing Agents; PC12 Cells; Piperidines; Potassium; Presynaptic Terminals; Rats; Subcellular Fractions; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles; Transfection; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2002 |
[Cardiac-hemodynamic effects of M3 receptor agonist on rat and rabbit hearts].
Topics: Animals; Choline; Female; Heart; Heart Rate; Hemodynamics; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Rabbits; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 2001 |
Modulation of electrically evoked acetylcholine release through cannabinoid CB1 receptors: evidence for an endocannabinoid tone in the human neocortex.
Topics: Acetylcholine; Adolescent; Adult; Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Brain Chemistry; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Child; Choline; Dose-Response Relationship, Drug; Dronabinol; Electric Stimulation; Endocannabinoids; Hemicholinium 3; Humans; Mice; Middle Aged; Morpholines; Naphthalenes; Neocortex; Nootropic Agents; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tritium | 2003 |
Choline acetyltransferase: regulation and coupling with protein kinase and vesicular acetylcholine transporter on synaptic vesicles.
Topics: Adenosine Triphosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Choline; Choline O-Acetyltransferase; Enzyme Activation; Enzyme Inhibitors; Gramicidin; Membrane Transport Proteins; Piperidines; Protein Kinase Inhibitors; Protein Kinases; Swine; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2004 |
[Relationship between M3 receptor and myocyte apoptosis induced by acute myocardial infarction].
Topics: Animals; Apoptosis; Choline; fas Receptor; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Piperidines; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Tumor Necrosis Factor; Superoxide Dismutase | 2004 |
Choline is transported by vesicular acetylcholine transporter.
Topics: Acetylcholine; Animals; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Choline; Intracellular Membranes; Membrane Transport Proteins; PC12 Cells; Piperidines; Quaternary Ammonium Compounds; Radioligand Assay; Rats; Subcellular Fractions; Tritium; Vesicular Acetylcholine Transport Proteins | 2004 |
M3-R/IK(M3)--a new target of antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Separation; Choline; Guinea Pigs; Heart Ventricles; Male; Myocytes, Cardiac; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2005 |
Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB).
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Transformed; Central Nervous System Agents; Choline; Cyclic N-Oxides; Donepezil; Endothelial Cells; Indans; Models, Biological; Nerve Tissue Proteins; Nitrogen Oxides; Organic Cation Transport Proteins; Piperidines; Plasma Membrane Neurotransmitter Transport Proteins; Rats; Symporters; Tacrine | 2005 |
Inhibition of human plasma cholinesterase by malachite green and related triarylmethane dyes: mechanistic implications.
Topics: Binding Sites; Butyrylthiocholine; Choline; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Humans; Hydrogen-Ion Concentration; Indans; Kinetics; Ligands; Methyl Green; Peripheral Nerves; Phenothiazines; Piperidines; Propidium; Rosaniline Dyes; Temperature; Toluidines | 2005 |
Effects of selegiline alone or with donepezil on memory impairment in rats.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Aziridines; Behavior, Animal; Choline; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Synergism; Escape Reaction; Fenclonine; Indans; Male; Maze Learning; Memory Disorders; Piperidines; Rats; Rats, Inbred F344; Reaction Time; Scopolamine; Selegiline; Time Factors | 2005 |
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.
Topics: Acetylcholine; Acetylcholinesterase; Atropine; Autocrine Communication; Caco-2 Cells; Cell Proliferation; Choline; Choline O-Acetyltransferase; Cholinergic Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dose-Response Relationship, Drug; Electrochemistry; Hemicholinium 3; HT29 Cells; Humans; Immunohistochemistry; Membrane Transport Proteins; Muscarinic Antagonists; Physostigmine; Piperidines; Polymerase Chain Reaction; Receptor, Muscarinic M3; RNA, Messenger; Tacrine | 2008 |
[Role of ventricular M3 receptor in arrhythmia resulted from cerebral-cardiac syndrome].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Choline; Electrocardiography; Heart Ventricles; Infarction, Middle Cerebral Artery; Male; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Potassium Chloride; Random Allocation; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2008 |
Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Calcium; Choline; Disease Models, Animal; Female; Guinea Pigs; Male; Myocytes, Cardiac; Ouabain; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2008 |
In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment.
Topics: Amyloid beta-Protein Precursor; Animals; Brain; Choline; Cholinesterase Inhibitors; Corpus Striatum; Creatine; Donepezil; Enzyme-Linked Immunosorbent Assay; Female; Frontal Lobe; Glutamic Acid; Hippocampus; Humans; Indans; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multivariate Analysis; Mutation; Parietal Lobe; Piperidines; Presenilin-1; Taurine | 2009 |
Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Cell Line, Transformed; Choline; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Indans; Male; Organic Cation Transport Proteins; Piperidines; Rats; Rats, Sprague-Dawley; Transfection | 2010 |
Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Aziridines; Benzodioxoles; Choline; Cognition Disorders; Donepezil; Hippocampus; Indans; Injections, Intraventricular; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Nerve Degeneration; Neuromuscular Blocking Agents; Neuroprotective Agents; Nootropic Agents; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Rats; Space Perception; Thailand | 2010 |
Effects of yokukansan and donepezil on learning disturbance and aggressiveness induced by intracerebroventricular injection of amyloid β protein in mice.
Topics: Aggression; Amyloid beta-Peptides; Animals; CHO Cells; Choline; Cricetinae; Cricetulus; Donepezil; Drugs, Chinese Herbal; Indans; Injections, Intraventricular; Learning; Membrane Transport Proteins; Mice; Piperidines; Protein Binding; Rats; Receptors, Cell Surface | 2011 |
Role of choline and glycine betaine in the formation of N,N-dimethylpiperidinium (mepiquat) under Maillard reaction conditions.
Topics: Alkaloids; Betaine; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Deuterium; Hot Temperature; Kinetics; Lysine; Maillard Reaction; Methylation; Models, Chemical; Molecular Structure; Molecular Weight; Piperidines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Chlorpheniramine; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hemorrhage; Histamine; Histamine Agonists; Histamine Antagonists; Hypotension; Hypothalamus, Posterior; Male; Microdialysis; Piperidines; Rats; Rats, Sprague-Dawley; Time Factors | 2015 |
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway.
Topics: Administration, Intravenous; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; Cholinergic Agonists; Dose-Response Relationship, Drug; Ischemia; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Reperfusion Injury; Signal Transduction; Structure-Activity Relationship; Vascular System Injuries | 2015 |
Effects of Ginkgo biloba Extract EGb 761, Donepezil and their Combination on Central Cholinergic Function in Aged Rats.
Topics: Acetylcholine; Aging; Animals; Brain; Choline; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Ginkgo biloba; Hippocampus; Indans; Male; Microdialysis; Neuroprotective Agents; Piperidines; Plant Extracts; Rats; Rats, Sprague-Dawley | 2015 |
Epoxyeicosatrienoic acids alleviate methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice.
Topics: Animals; Cell Line; Cell Line, Tumor; Chemokines; Choline; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytokines; Diet; Down-Regulation; Hep G2 Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Liver; Macrophages; Methionine; Mice; NF-kappa B; Non-alcoholic Fatty Liver Disease; Phenylurea Compounds; Piperidines; PPAR alpha; RNA, Messenger; Signal Transduction; Sterol Regulatory Element Binding Protein 1; THP-1 Cells; Vascular Cell Adhesion Molecule-1 | 2019 |
LC-MS/MS-based metabolomics approach revealed novel phytocompounds from sugarcane rind with promising pharmacological value.
Topics: Acetylcholine; Anthocyanins; Antioxidants; Choline; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flavonoids; Metabolomics; Methoxydimethyltryptamines; Piperidines; Plant Extracts; Saccharum; Tandem Mass Spectrometry | 2022 |