choline has been researched along with folic acid in 359 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (30.64) | 18.7374 |
| 1990's | 21 (5.85) | 18.2507 |
| 2000's | 52 (14.48) | 29.6817 |
| 2010's | 131 (36.49) | 24.3611 |
| 2020's | 45 (12.53) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Poirier, LA | 2 |
| Rogers, AE | 1 |
| Douglas, CR; Edds, GT; Harms, RH; Wilson, HR | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
| Bowers, JA; Engler, PP | 1 |
| Petri, WA; Poirier, LA | 1 |
| Asoklis, K; Asoklis, R | 1 |
| Hieb, WF; Lu, NC; Stokstad, EL | 1 |
| Cross, DR; James, SJ; Miller, BJ | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Olszewski, AJ | 1 |
| Bhandari, SD; Fortney, T; McMartin, KE | 1 |
| Pesti, GM; Rowland, GN; Ryu, KS | 1 |
| Locniskar, M; Newberne, PM | 1 |
| Newberne, PM; Rogers, AE | 1 |
| James, SJ; Yin, L | 1 |
| Bhandari, SD; Joshi, SK; McMartin, KE | 1 |
| Bialkowska, M; McCully, KS; Olszewski, AJ; Rudnicki, S; Szostak, WB | 1 |
| Fisler, JS; McKee, R; Sun, S; Swendseid, ME | 1 |
| Collins, RC; Olney, JW; Sloviter, RS | 1 |
| Blair, R; Newsome, F | 1 |
| Boyd, JN; Graham, ES; Graham, TC; Tennant, BC | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 1 |
| Drill, VA; Laird, RD | 1 |
| Chambers, JW; Nelson, AB; Neumann, AL; Ray, EE; Smith, GS | 1 |
| Kaul, S; Saxena, SC | 1 |
| Poirier, LA; Whitehead, VM | 1 |
| Konttinen, K; Oura, E; Suomalainen, H | 1 |
| Dadd, RH | 1 |
| Daniel, JC | 1 |
| Cairella, M | 1 |
| Ournac, A | 1 |
| Lanfranchi, R; Sabetta, F | 1 |
| Woodard, JC | 1 |
| Bianchi, V; Borri, P; Vittori, C | 1 |
| Blaker, GJ; Pirt, SJ | 1 |
| Alford, JA; Hargrove, RE; Mattingly, WA; McDonough, FE; Posati, LP | 1 |
| Monnens, LA; Schretlen, ED; Sengers, RC; Trijbels, JM; van der Zee, SP; Vrenken, JA | 1 |
| Margen, S | 1 |
| Bouveng, R | 1 |
| Kirk, JE | 1 |
| Heide, M | 1 |
| Wildhirt, E | 1 |
| Lansing, AI; Lieberman, I; Pekarthy, JM; Short, J | 1 |
| Batra, KK; Buehring, KU; Stokstad, EL | 1 |
| Fuller, HL; Keshavarz, K | 1 |
| Bais, BS; Shukla, TN | 1 |
| Arnaud, SB; Barness, LA; Morrow, G; Oski, FA; Williams, ML | 1 |
| Manfredi, LM; Mitolo, M | 1 |
| Landureau, JC | 1 |
| Newberne, PM; Woodard, JC | 1 |
| Daniel, LJ; Lust, G | 1 |
| Branco, CL; Tôrres, IN | 1 |
| Hegsted, DM; Vitale, JJ | 1 |
| Hegsted, DM; McCombs, HL; Roach, AM | 1 |
| Contestabile, A; Migani, P; Poli, A; Villani, L | 1 |
| Hughes, JR; Matalon, R; Michals, K; Naidu, S | 1 |
| Avila, JL; Bretaña, A; Pérez-Kepp, R | 1 |
| Maletta, GJ; Vatassery, GT | 1 |
| Rose, RC | 1 |
| Avila, A; Avila, JL | 1 |
| Eitenmiller, RR; Pesti, GM; Roberson, KD; Ryu, KS | 1 |
| Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ | 1 |
| Baik, MG; Choi, CB; Keller, WL; Park, CS | 1 |
| da Costa, KA; Kim, YI; Mason, JB; Miller, JW; Nadeau, M; Selhub, J; Smith, D; Zeisel, SH | 1 |
| Henning, SM; Jacob, RA; Swendseid, ME; Wu, MM | 1 |
| Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E | 1 |
| Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G | 1 |
| Kim, SH; Moon, YS; Park, CS | 1 |
| Alonso-Aperte, E; Varela-Moreiras, G | 1 |
| Henning, SM; Swendseid, ME | 1 |
| Appling, DR; Kastanos, E; Pasternack, LB; Woldman, YY | 1 |
| Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL | 1 |
| Glade, MJ | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K | 1 |
| Niculescu, MD; Zeisel, SH | 2 |
| Hirosawa, K; Hishida, A; Ikegaya, N; Katoh, S; Kimura, M; Kumagai, H | 1 |
| Fenech, M; Wang, X | 1 |
| Jirtle, RL; Waterland, RA | 1 |
| Keshavarz, K | 1 |
| SMITH, P; STEKOL, JA; WEISS, K; WEISS, S | 1 |
| FATTERPAKER, P; MARFATIA, U; SREENIVASAN, A | 1 |
| SMITH, EL | 1 |
| DAY, PL; DINNING, JS; NEATROUR, R | 1 |
| BRIGGS, GM; DAFT, FS | 1 |
| ANDERSON, EI; HSU, PT; STEKOL, JA; WATJEN, A; WEISS, S | 1 |
| BACQ, ZM; LIEBECQ-HUTTER, S | 1 |
| LIEBECQ-HUTTER, S | 1 |
| FRITZ, IB | 1 |
| DUPONT, P; FRITZ, IB | 1 |
| TOTTER, JR | 1 |
| BROQUIST, HP | 1 |
| PARIGI, A | 1 |
| SAUBERLICH, HE | 1 |
| DALAL, FR; FATTERPAKER, P; REGE, DV; SREENIVASAN, A | 1 |
| DIEGNER, S | 1 |
| ROTZSCH, W; THOMITZEK, WD | 1 |
| BIEBER, LL; CHELDELIN, VH; NEWBURGH, RW | 1 |
| CAVINS, JF; CHRISTIANSON, DD; DIMLER, RJ; WALL, JS | 1 |
| REEVES, RE | 1 |
| KOCH, A; SCHWARZ, I | 1 |
| LUKOMSKII, PE | 1 |
| LITTMAN, ML; MIWATANI, T | 1 |
| BALL, CR | 1 |
| HOSEIN, EA | 1 |
| RYALL, RW; STONE, N; WATKINS, JC | 1 |
| BLUMENSTEIN, J | 1 |
| GROS, H | 1 |
| DRILL, VA; LAIRD, RD; MCCORMICK, HM | 1 |
| FRITZ, IB; SCHULTZ, SK | 1 |
| JONES, RS; MACDONALD, RA; PECHET, GS | 1 |
| GEER, BW; VOVIS, GF | 1 |
| HOSEIN, EA; ORZECK, A | 1 |
| DOWE, GH; WHITTAKER, VP | 1 |
| FRAENKEL, GS; FRIEDMAN, S; HINTON, T; LASZLO, S; NOLAND, JL | 1 |
| HEUSER, GF; NORRIS, LC; YOUNG, RJ | 1 |
| Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM | 1 |
| BANDELIN, FJ; TUSCHHOFF, JV | 1 |
| HALE, OM; SCHAEFER, AE | 1 |
| KNOWLES, JL; SCHAEFER, AE | 1 |
| SALMON, WD; SCHAEFER, EA; STRENGTH, DR | 1 |
| CALETTI, G | 1 |
| STEKOL, JA; WEISS, KW; WEISS, S | 1 |
| Carreras, O; Delgado-Villa, MJ; García-Benítez, O; Murillo, ML | 1 |
| SALMON, WD; SCHAEFER, AE | 1 |
| DUCKWORTH, J; ELLINGER, GM | 1 |
| DAY, PL; DINNING, JS; KEITH, CK | 1 |
| DAVIS, PL; DAY, PL; DINNING, JS; KEITH, CK | 1 |
| DITTRICH, H; SCHMID, S | 1 |
| Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE | 1 |
| Zeisel, SH | 6 |
| Olthof, MR; Verhoef, P | 1 |
| Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
| Fokkema, MR; Holm, PI; Muskiet, FA; Ueland, PM; van der Dijs, FP; Velzing-Aarts, FV | 1 |
| Choi, SW; Mason, JB | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| da Costa, KA; Fischer, LM; Kohlmeier, M; Zeisel, SH | 1 |
| Asoh, M; Furukawa, M; Kanno, T; Kojima, T; Sakurai, T; Yonekubo, A | 1 |
| Gulevich, RG; Latypov, IF; Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN; Vsevolodov, EB | 1 |
| Cho, E; Colditz, GA; Dougherty, L; Jacques, P; Selhub, J; Willett, WC; Zeisel, SH | 1 |
| Maloney, CA; Rees, WD; Wilson, FA | 1 |
| Batra, V; Kesavan, V; Mishra, KP | 1 |
| Craciunescu, CN; da Costa, KA; Fischer, LM; Niculescu, MD; Zeisel, SH | 1 |
| Batra, V; Mishra, KP | 1 |
| Dolinoy, DC; Lin, JR; Shi, X; Smith, CA; Tahiliani, KG; Waterland, RA | 1 |
| Blouet, C; Daré, S; Hammiche, A; Huneau, JF; Mariotti, F; Tomé, D | 1 |
| Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Bots, ML; Dalmeijer, GW; Olthof, MR; van der Schouw, YT; Verhoef, P | 1 |
| Hay, SM; Maloney, CA; Rees, WD | 1 |
| Allen, RH; daCosta, KA; Fischer, LM; Kwock, L; Lu, TS; Stabler, SP; Stewart, PW; Zeisel, SH | 1 |
| Ahsan, H; Baron, JA; Chen, Y; Gamble, MV; Graziano, JH; Heck, JE; Howe, GR; Parvez, F; Slavkovich, V | 1 |
| Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA | 1 |
| Abratte, CM; Caudill, MA; Li, R; Moriarty, DJ; Wang, W | 1 |
| Lim, U; Ziegler, RG | 1 |
| Davis, JE | 2 |
| Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH | 1 |
| Caudill, MA; Ivanov, AA; Li, R; Maletz, CV; Moriarty, DJ; Solis, C; Tran, S; Veenema, K; Wang, W | 1 |
| Abratte, CM; Axume, J; Caudill, MA; Li, R; Moriarty, DJ; Wang, W | 1 |
| Abratte, CM; Caudill, MA; Hung, J; Li, R; Moriarty, DJ; Wang, W | 1 |
| Batra, V; Devasagayam, TP | 1 |
| Carmichael, SL; Correa, A; Olney, RS; Shaw, GM; Yang, W | 1 |
| Drevon, CA; Konstantinova, SV; Tell, GS; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Calder, AG; Holtrop, G; Lobley, GE; O'Kennedy, N; Rees, WD; van den Borne, JJ; Wilson, FA | 1 |
| Caudill, MA; Hinkis, S; Ivanov, A; Nash-Barboza, S | 1 |
| Cantoral, A; Chen, J; Galván-Portillo, MV; Hernandez-Ramirez, RU; Herrera-Goepfert, R; López-Carrillo, L; Oñate-Ocaña, LF; Palma-Coca, O; Torres-Sanchez, L | 1 |
| Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S | 1 |
| Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN | 1 |
| Blom, HJ; Carmichael, SL; Finnell, RH; Shaw, GM; Ueland, PM; Vollset, SE; Yang, W | 1 |
| Dziegelewska, M; Hozyasz, KK; Jagodzinski, PP; Mostowska, A; Wojcicki, P | 1 |
| Batra, V; Devasagayam, TP; Sridhar, S | 1 |
| Audonnet, S; Beck, B; Blaise, S; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Koziel, V; Ortiou, S; Pourié, G; Rio, MC; Tomasetto, C | 1 |
| Cho, E; Hankinson, SE; Holmes, MD; Willett, WC | 1 |
| Beckman, KB; Cropley, JE; Martin, DI; Suter, CM | 1 |
| Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH | 1 |
| COTTINGHAM, E; MILLS, CA; TAYLOR, E | 1 |
| Adriaenssens, T; Anckaert, E; Romero, S; Smitz, J | 1 |
| Hollenbeck, CB | 1 |
| Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN | 1 |
| Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
| Blusztajn, JK; Crivello, NA; Joseph, JA; Shukitt-Hale, B; Smith, DE | 1 |
| Dowd, SE; Harris, RA; Kellermayer, R; Schaible, TD; Smith, CW | 1 |
| Abarinov, EV; Allen, RH; Beaudin, AE; Chu, S; Noden, DM; Perry, CA; Stabler, SP; Stover, PJ | 1 |
| Jagodziński, PP; Lianeri, M; Mostowska, A; Myka, M; Roszak, A | 1 |
| Jagodziński, PP; Lianeri, M; Marianowski, P; Mostowska, A; Skrzypczak, J; Szczepańska, M; Wirstlein, P | 1 |
| Caudill, MA; West, AA | 1 |
| Campion, J; Cordero, P; Martínez, JA; Milagro, FI | 2 |
| Toriello, HV | 1 |
| Brenna, JT; Carrier, BJ; Caudill, MA; Chew, TW; Gregory, JF; Jiang, X; Lusa, AL; Malysheva, OV; Wang, W; West, AA; Yan, J | 1 |
| Chen, CS; Juo, SH; Ko, CH; Kuo, YT; Lee, CC; Li, CW; Lin, HF; Liu, GC; Tsai, HY; Yeh, YC; Yen, CF | 1 |
| Böhlke, M; Broersen, LM; Hageman, RJ; Kamphuis, PJ; Maher, TJ; van Wijk, N; Watkins, CJ; Wurtman, RJ | 1 |
| Abarinov, EV; Beaudin, AE; Caudill, M; Malysheva, O; Perry, CA; Stover, PJ | 1 |
| Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA | 1 |
| Shane, B | 1 |
| Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
| Jagodzinski, PP; Kędzia, H; Lianeri, M; Mostowska, A; Pawlik, P; Sajdak, S | 1 |
| Drake, AJ; Holmes, MC; Kerrigan, D; Seckl, JR; Wyrwoll, CS | 1 |
| Ballard, MS; Ko, J; Sun, M | 1 |
| Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L | 1 |
| Ozaki, M; Parle-McDermott, A | 1 |
| Allen, RH; Beaudin, AE; Perry, CA; Stabler, SP; Stover, PJ | 1 |
| Baccarelli, A; Boeke, CE; Burris, HH; Gillman, M; Kleinman, KP; Litonjua, AA; Rifas-Shiman, SL; Tarantini, L | 1 |
| Fenech, M; Lu, L; Ni, J; Wang, X; Xu, W; Zhou, T | 1 |
| Anderson, SE; Calder, AG; Holtrop, G; Lobley, GE; Rees, WD; Wilson, FA | 1 |
| Allen, LH | 1 |
| Gillman, MW; Oken, E; Rifas-Shiman, SL; Villamor, E | 1 |
| Bossenmeyer-Pourie, C; Bressenot, A; Chevaux, JB; Coste, F; Gauchotte, G; Germain, A; Guéant, JL; Peyrin-Biroulet, L; Pooya, S; Vignaud, JM | 1 |
| Beland, FA; Collins, L; de Conti, A; Fuscoe, JC; Han, T; Kobets, T; Koturbash, I; Kutanzi, K; Latendresse, JR; Melnyk, S; Pogribny, IP; Ross, SA; Rusyn, I; Shymonyak, S; Tryndyak, V | 1 |
| Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Esashi, T; Hanai, M | 1 |
| Chen, YM; Ho, SC; Li, B; Lin, FY; Mo, XF; Pan, MX; Wang, L; Zhang, CX | 1 |
| Deckersbach, T; Nierenberg, AA; Peters, AT; Sylvia, LG | 1 |
| Eggersdorfer, M; Kraemer, K; Schaumberg, DA; Semba, RD | 1 |
| Bertolo, RF; McBreairty, LE | 2 |
| Awaji, H; Horie, K; Kim, M; Nakata, R; Sugiyama, A | 1 |
| Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L | 1 |
| Forman, MR; Hernandez, LM; Lupo, PJ; Peterson, CB; Shete, S; Spitz, MR; Swartz, MD; Vannucci, M; Wu, X | 1 |
| Boeke, CE; Gillman, MW; Hughes, MD; Oken, E; Rifas-Shiman, SL; Villamor, E | 1 |
| Beland, FA; de Conti, A; James, SJ; Kutanzi, K; Latendresse, JR; Melnyk, S; Montgomery, B; Muskhelishvili, L; Pogribna, M; Pogribny, IP; Rusyn, I; Tryndyak, V | 1 |
| De Vivo, I; Giovannucci, E; Hankinson, SE; Liu, JJ; Prescott, J; Rosner, B | 1 |
| Mehedint, MG; Zeisel, SH | 1 |
| Delaney, C; Hewagama, A; Hoeltzel, MF; Johnson, K; Mickelson, B; Richardson, BC; Sawalha, AH; Strickland, FM; Wu, A; Yung, R | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM | 1 |
| Arning, E; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Greene, ND; Jerome-Majewska, L; Krupenko, NI; Leung, KY; MacKenzie, RE; Malysheva, OV; Rozen, R | 1 |
| Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT | 1 |
| Ali, NS; Michels, KB; Osterhues, A | 1 |
| Obeid, R | 1 |
| Benoist, JF; Blom, HJ; Imbard, A | 1 |
| Clark, JD; Liang, D; Sahbaie, P; Sun, Y | 1 |
| Cho, K; Choi, WS; Crane, CL; Park, CS | 1 |
| Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Buck, K; Caudill, MA; Cheng, TY; Hou, L; Malysheva, O; Maneval, DR; Miller, JW; Neuhouser, ML; Song, X; Ulrich, CM; Xiao, L; Zheng, Y | 1 |
| de Waal, H; Kamphuis, PJ; Lansbergen, MM; Maestú, F; Scheltens, P; Stam, CJ; van Straaten, EC; Wieggers, RL | 1 |
| Berger-Sweeney, J; Ricceri, L; Schaevitz, L | 1 |
| Bertoia, ML; Cooke, JP; Joosten, MM; Mittleman, MA; Mukamal, KJ; Pai, JK; Rimm, EB | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 2 |
| Brody, LC; Fan, R; Kirke, PN; Liu, A; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM | 1 |
| Aliani, M; Eskin, MN; Giesbrecht, HE; Suh, M; Young, JK | 1 |
| Brereton, NH; Guerrerio, AL; Hauck, SA; Henry, BJ; Keet, CA; Oh, S; Robbins, KA; Stasinopoulos, DM; Wood, RA | 1 |
| Brosnan, JT; Brosnan, ME; Lamarre, SG; MacFarlane, AJ; MacMillan, L; Morrow, GP; Young, SK | 1 |
| Dubrova, YE; Glen, CD; McVeigh, LE; Voutounou, M | 1 |
| Hamill, LL; Keaveney, EM; McNulty, H; Molloy, AM; Piironen, V; Price, RK; Shewry, PR; Strain, JJ; Ueland, PM; von Reding, W; Wallace, JM; Ward, JL; Ward, M; Welch, RW | 1 |
| Abate, L; Amore, M; Cocito, L; Emberti Gialloreti, L; Guida, S; Krueger, F; Massucco, D; Mattei, C; Pardini, M; Sassos, D; Serrati, C | 1 |
| Ishii, D; Kawai, K; Mashimo, Y; Matsuda, S; Matsuzawa, D; Shimizu, E; Sutoh, C; Tomizawa, H | 1 |
| Aguiar, S; de Carvalho, AM; Ferrari, A; Marchioni, DM; Steluti, J; Teixeira, J | 1 |
| Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
| Hoeflich, A; Muráni, E; Nuchchanart, W; Oster, M; Ponsuksili, S; Trakooljul, N; Wimmers, K; Wirthgen, E; Zeyner, A | 1 |
| Coathup, V; Smith, L; Wheeler, S | 1 |
| Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Cho, K; Choi, WS; Crane, CL; Mabasa, L; Park, CS; Singh, RK | 1 |
| Lane, RH; Majnik, AV | 1 |
| Du, YF; Lin, FY; Long, WQ; Luo, WP; Mo, XF; Xu, M; Yan, B; Zhang, CX | 1 |
| Drews, K | 1 |
| Caudill, MA; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Malysheva, O; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Beland, FA; Fuscoe, JC; Han, T; Pogribny, IP; Ross, SA; Tryndyak, VP | 1 |
| Carrier, B; Caudill, MA; Chuang, JC; Cohen, VV; Fomin, VG; Ganti, A; Ganz, AB; Lopez, YS; Lovesky, J; Malysheva, OV; Mohan, S; Mudrak, E; Shields, K; Stover, JA; Swersky, CC; Taeswuan, S; Vitiello, GA; Yan, J | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Hultdin, J; Johansson, I; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Van Guelpen, B | 1 |
| Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C; Widmann, T | 1 |
| Chen, Y; Hong, Y; Wang, W; Xiao, Z; Yu, L | 1 |
| Devlieger, R; Duca, RC; Freson, K; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Straetmans, D; Van Herck, E | 1 |
| Giardina, C; Hanley, MP; Kadaveru, K; Perret, C; Rosenberg, DW | 1 |
| Basta, PV; Carrier, KS; Diskin, SJ; Engel, SM; Maris, JM; Maxen, C; Mazul, AL; Naranjo, A; Olshan, AF; Siega-Riz, AM; Vaksman, Z; Weinberg, CR; Zou, F | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; Randell, EW; Robinson, JL | 1 |
| Bertolo, RF; Brunton, JA; Harding, SV; Robinson, JL | 1 |
| de Vos, WM; Jaakkola, T; Kolho, KL; Pessia, A; Velagapudi, V | 1 |
| Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK | 1 |
| Chauhan, A; Jaiswal, SK; Kumar, A; Lakhotia, AR; Rai, AK; Sukla, KK | 1 |
| Arning, E; Bahous, RH; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Hou, W; Jerome-Majewska, LA; Malysheva, OV; Rozen, R | 1 |
| A S Langie, S; Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S | 1 |
| Block, RC; Fernandez, ID; Groth, SW; Ossip, DJ; Stewart, PA; Wixom, N | 1 |
| Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Langie, SAS; Pauwels, S | 1 |
| Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Langie, SAS; Pauwels, S; Truijen, I | 1 |
| Du, YF; Huang, J; Huang, WQ; Luo, WP; Mo, XF; Xu, M; Yan, B; Zhang, CX | 1 |
| Wu, MM; Yang, F | 1 |
| Aylsworth, AS; Botto, LD; Carmichael, SL; Correa, A; Gilboa, SM; Langlois, PH; Luben, TJ; Nembhard, WN; Olshan, AF; Richmond-Bryant, J; Shaw, GM; Stingone, JA | 1 |
| Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S | 1 |
| Attia, JR; Butler, T; Chan, EC; Collins, CE; Evans, TJ; Hure, AJ; Mossman, D; Smith, R; Smith, T; Taylor, RM; Wong-Brown, MW | 1 |
| Bainbridge, S; Fontaine-Bisson, B; McGee, M | 1 |
| Ray, D; Richardson, BC; Strickland, FM | 1 |
| Barzilay, E; Berger, H; Caudill, MA; Croxford, R; Kim, YI; Ly, A; Malysheva, O; Masih, SP; Moon, A; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Bagnoli, M; Mezzanzanica, D; Napoli, A; Rizzo, A; Roggiani, F; Tomassetti, A | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Cai, Y; Guo, H; He, M; Hou, FF; Huo, Y; Li, GF; Li, Y; Liu, S; Nie, J; Qin, X; Qiu, B; Wang, B; Wang, Y; Xie, L; Xu, X; Zhang, H; Zhao, BX; Zhu, F | 1 |
| Dahdoul, T; Nijhout, HF; Reed, MC; Sadre-Marandi, F | 1 |
| Fuchida, T; Goto, T; Ishii, D; Matsuzawa, D; Sahara, Y; Shimizu, E; Sutoh, C | 1 |
| Chmurzynska, A; Radziejewska, A | 1 |
| Collins, CE; Evans, TJ; Hure, AJ; Smith, R; Taylor, RM | 1 |
| Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA | 1 |
| Bassett, JK; Boussioutas, A; Brinkman, MT; Dugué, PA; English, DR; Giles, GG; Hodge, AM; Joo, JE; Milne, RL; Mitchell, H; Southey, MC; Wong, EM | 1 |
| Crider, KS; Mitchell, AA; Parker, SE; Petersen, JM; Tinker, SC; Werler, MM | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; KurzawiŃska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Wolski, H | 1 |
| Bustamante, A; Cakora, P; Felder, MR; Hall-South, A; Owen, A; Shorter, KR; Smith, N; Vrana, PB; Yadon, N | 1 |
| Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
| Blusztajn, JK; Caudill, MA; Klatt, KC; Wallace, TC; Zeisel, SH | 1 |
| Cui, Y; Guan, CY; Ma, X; Song, G; Sun, DG; Wang, R; Xia, HF | 1 |
| Chu, KY; Huang, KT; Huang, RS; Ku, WC; Lee, CN; Liu, CY; Shen, YL | 1 |
| Chmurzynska, A; Martínez, JA; Milagro, FI; Muzsik, A; Radziejewska, A | 1 |
| Ampong, I; Eid, N; Griffiths, HR; Morgan, HL; Rouillon, C; Watkins, AJ | 1 |
| Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
| Elango, R | 1 |
| Christensen, KE; Issa, JJ; Jelinek, J; Leclerc, D; Rozen, R | 1 |
| Jové, M; Maldonado, J; Martín-Masot, R; Mota-Martorell, N; Nestares, T; Pamplona, R | 1 |
| Anderson, GH; Bottiglieri, T; Caudill, MA; Hammoud, R; Kubant, R; Malysheva, OV; Pannia, E; Wasek, B | 1 |
| Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
| Clark, AM; Freedman, R; Hoffman, MC; Hunter, SK; Law, AJ; Roberts, A | 1 |
| Eyal, S; Moushaev, S; Shmuel, M; Tetro, N | 1 |
| Andraos, S; Cameron-Smith, D; Chia, PHP; D'Souza, RF; Gillies, NA; Knowles, SO; Milan, AM; Mitchell, CJ; Mitchell, SM; Ramzan, F; Roy, NC; Sharma, P; Sjödin, A; Wagner, KH; Zeng, N | 1 |
| Clark, AM; Freedman, R; Hoffman, MC; Hunter, SK; Law, AJ | 1 |
| Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E | 1 |
| Aardema, NDJ; Bunnell, ML; Cho, CE; Hintze, KJ; Mjaaseth, UN; Norris, JC; Ward, RE | 1 |
| Devlieger, R; Godderis, L; Hoeylaerts, S; Huybrechts, I; Koppen, G; Pauwels, S; Van Opstal, A | 1 |
| Chang, CY; Chang, TY; Doong, JY; Huang, RS; Kuo, CS; Lee, FJ; Lin, YS; Wang, BW; Wu, CH | 1 |
| Aghajafari, F; Dewey, D; England-Mason, G; Field, CJ; Irvine, N | 1 |
| Cruz, M; Diaz-Flores, M; Fernandez-Osornio, LF; Gomez-Diaz, RA; Gonzalez-Carranza, E; Hernández-Pineda, J; Maldonado-Rodriguez, R; Mondragon-Gonzalez, R; Sharma, T; Valladares-Salgado, A; Wacher, NH | 1 |
| Chang, HJ; Kim, J; Lee, J; Oh, JH; Shin, A; Sohn, DK | 1 |
| Chmurzynska, A; Muzsik-Kazimierska, A; Nikrandt, G; Szwengiel, A | 1 |
| Avigan, MI; Beland, FA; da Costa, GG; de Conti, A; Nagumalli, SK; Pogribny, IP; Rusyn, I; Tryndyak, VP; Willett, RA | 1 |
| Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
| Alvarez, JA; Cui, X; Ramakrishnan, U; Schoen, MS; Singh, RH; Ziegler, TR | 1 |
| Bo, Y; Cao, Y; Dou, W; Duan, D; Fu, W; Liu, Y; Lyu, Q; Ma, S; Zeng, F; Zhao, X | 1 |
| Holzgreve, W; Obeid, R; Pietrzik, K | 1 |
| Baccarelli, AA; Bozack, AK; Cardenas, A; DeMeo, DL; Duca, RC; Godderis, L; Hivert, MF; Oken, E; Parsons, E; Rifas-Shiman, SL | 1 |
| Caton, JS; Crouse, MS; Cushman, RA; Dahlen, CR; Freetly, HC; King, LE; Lee, RT; Lindholm-Perry, AK; Neville, BW; Oliver, WT; Reynolds, LP; Syring, JG; Ward, AK | 1 |
| Cuffe, JSM; Moritz, KM; Steane, SE | 1 |
| Devlin, AM; Dhillon, AK; Elango, R; Innis, SM; Wiedeman, AM; Wu, BT | 1 |
| Bell, RC; Dewey, D; England-Mason, G; Field, CJ; Giesbrecht, GF; Irvine, N; Kinniburgh, DW; Letourneau, N; MacDonald, AM; Martin, JW | 1 |
| Hurley, L; Ille, S; Jadavji, NM; Jauhal, J; Malysheva, OV; Pull, K | 1 |
| Putilina, MV | 1 |
| Antonova, IV; Kozubenko, OV; Turchaninov, DV; Vilms, EA | 1 |
| Brown, AR; Carlson, SE; Crawford, SA; Gajewski, BJ; Kerling, EH; Sullivan, DK; Teruel Camargo, J; Valentine, CJ | 1 |
| Alegria-Lertxundi, I; Arroyo-Izaga, M; de Pancorbo, MM; Martín-Fernández-de-Labastida, S | 1 |
| Feiten, AF; Ittner, LM; Ke, YD; Sontag, E; Sontag, JM; Taleski, G; van Hummel, A | 1 |
| Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H | 1 |
| Carmichael, SL; Darling, AM; Desrosiers, TA; Nestoridi, E; Parker, SE; Petersen, JM; Politis, MD; Shaw, GM; Smith-Webb, RS; Werler, MM; Yazdy, MM | 1 |
| Buckley, D; de Vries, MM; Hasken, JM; Kalberg, WO; Marais, AS; May, PA; Parry, CDH; Seedat, S | 1 |
| Jadavji, NM; McKee, AM; Nuthi, M; Virdi, S | 1 |
| Esfandiarei, M; Folk, R; Gusek, B; Jackson, S; Jadavji, NM; Kang, J; Pull, K | 1 |
47 review(s) available for choline and folic acid
| Article | Year |
|---|---|
B-vitamin retention in meat during storage and preparation. A review.
Topics: Animals; Biotin; Choline; Drug Stability; Folic Acid; Food Handling; Food Preservation; Meat; Muscles; Nicotinic Acids; Pantothenic Acid; Poultry Products; Pyridoxine; Riboflavin; Sheep; Swine; Temperature; Thiamine; Time Factors; Vitamin B Complex | 1976 |
Roles of micronutrients in cancer prevention: recent evidence from the laboratory.
Topics: Animals; Ascorbic Acid; Choline; Female; Folic Acid; Methionine; Mice; Minerals; Neoplasms, Experimental; Rats; Selenium; Vitamin A; Vitamins; Zinc | 1990 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Involvement of water-soluble vitamins in diseases of swine.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Biotin; Choline; Choline Deficiency; Folic Acid; Folic Acid Deficiency; Niacin; Nutritional Requirements; Pantothenic Acid; Pyridoxine; Riboflavin; Riboflavin Deficiency; Solubility; Swine; Swine Diseases; Thiamine; Thiamine Deficiency; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins; Water | 1985 |
Insect nutrition: current developments and metabolic implications.
Topics: Amino Acids; Animals; Aphids; Ascorbic Acid; Choline; Coleoptera; Cystine; DNA; Drosophila melanogaster; Fatty Acids; Folic Acid; Glycine; Insecta; Lepidoptera; Methionine; Minerals; Nutritional Physiological Phenomena; Proline; RNA; Sterols; Tyrosine; Urea; Vitamin B 12; Vitamin E | 1973 |
[Vitamins of wine].
Topics: Aminobenzoates; Ascorbic Acid; Biotin; Choline; Fermentation; Flavonoids; Folic Acid; Food Additives; Food Preservation; Food-Processing Industry; Fruit; Inositol; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Vitamin B 12; Vitamins; Wine | 1970 |
Recent advances in the use of selective neuron-destroying agents for neurobiological research.
Topics: Animals; Aziridines; Choline; Colchicine; Folic Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Lectins; Mitogens; Mustard Compounds; Nerve Degeneration; Nervous System; Neurons; Piperidines; Pyrrolidonecarboxylic Acid; Quinolinic Acid; Quinolinic Acids | 1984 |
Water-soluble vitamin absorption in intestine.
Topics: 4-Aminobenzoic Acid; Animals; Ascorbic Acid; Biological Transport; Biotin; Choline; Folic Acid; Humans; Intestinal Absorption; Nicotinic Acids; Pyridoxine; Riboflavin; Solubility; Thiamine; Vitamins | 1980 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms | 1996 |
Nutritional importance of choline for brain development.
Topics: Animals; Apoptosis; Brain; Cell Division; Cell Movement; Cell Proliferation; Choline; Female; Folic Acid; Gene Expression Regulation, Developmental; Homocysteine; Humans; Male; Memory; Neurons; Pregnancy | 2004 |
Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Folic Acid; Homocysteine; Humans; Lipids | 2005 |
Effects of alcohol on folate metabolism: implications for carcinogenesis.
Topics: Animals; Betaine; Biological Availability; Central Nervous System Depressants; Choline; Ethanol; Folic Acid; Humans; Neoplasms | 2005 |
Perinatal choline influences brain structure and function.
Topics: Brain; Choline; Female; Fetal Development; Folic Acid; Humans; Infant, Newborn; Lactation; Male; Methionine; Nootropic Agents; Perinatal Care; Pregnancy | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
The fetal origins of memory: the role of dietary choline in optimal brain development.
Topics: Brain; Choline; Diet; Female; Folic Acid; Humans; Infant; Methionine; Nootropic Agents; Pregnancy; Sex Factors | 2006 |
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
Topics: Animals; Brain; Choline; Choline Deficiency; Diet; Epigenesis, Genetic; Estrogens; Folic Acid; Humans; Methionine; Nutritional Requirements; Polymorphism, Genetic; Response Elements; Vitamin B Complex | 2007 |
Is maternal diet supplementation beneficial? Optimal development of infant depends on mother's diet.
Topics: Adult; Choline; Diet; Dietary Supplements; Docosahexaenoic Acids; Female; Folic Acid; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Iodine; Male; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy; Prenatal Nutritional Physiological Phenomena | 2009 |
Importance of methyl donors during reproduction.
Topics: Brain; Choline; Female; Fetal Development; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Methylation; Neural Tube Defects; Nootropic Agents; Nutritional Requirements; Pregnancy; Prenatal Nutritional Physiological Phenomena; Vitamin B Complex | 2009 |
Nutritional genomics: defining the dietary requirement and effects of choline.
Topics: Animals; Choline; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Nutrigenomics; Nutritional Requirements; Polymorphism, Single Nucleotide; Pregnancy | 2011 |
Genetic variation: impact on folate (and choline) bioefficacy.
Topics: Biological Availability; Choline; Epistasis, Genetic; Folic Acid; Genetic Variation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2) | 2010 |
The impact of nutrition on differential methylated regions of the genome.
Topics: Adult; Amino Acids; Animals; Choline; DNA Methylation; Female; Folic Acid; Food; Genistein; Genome, Human; Humans; Leptin; Methionine; Pregnancy; Proteins | 2011 |
B vitamins in breast milk: relative importance of maternal status and intake, and effects on infant status and function.
Topics: Breast Feeding; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Lactation; Maternal Nutritional Physiological Phenomena; Milk, Human; Nutritional Status; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Nutrient-based therapies for bipolar disorder: a systematic review.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Choline; Chromium; Dietary Supplements; Fatty Acids, Omega-3; Folic Acid; Humans; Inositol; Lipotropic Agents; Magnesium; Trace Elements; Tryptophan; Vitamin B Complex | 2013 |
The nutritional burden of methylation reactions.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines | 2013 |
Choline's role in maintaining liver function: new evidence for epigenetic mechanisms.
Topics: Animals; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Folic Acid; Gene Expression; Histones; Humans; Liver; Liver Cirrhosis; Models, Animal; Polymorphism, Genetic; S-Adenosylmethionine | 2013 |
The role of folic acid fortification in neural tube defects: a review.
Topics: Biological Availability; Choline; Edible Grain; Female; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Pregnancy; Recommended Dietary Allowances; United States; Vitamin B 12 | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
One-carbon metabolism in neurodevelopmental disorders: using broad-based nutraceutics to treat cognitive deficits in complex spectrum disorders.
Topics: Carbon; Choline; Cognition Disorders; Developmental Disabilities; Dietary Supplements; Folic Acid; Humans | 2014 |
Nutrition implications for fetal alcohol spectrum disorder.
Topics: Alcohol Drinking; Animals; Antioxidants; Brain; Choline; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Female; Fetal Alcohol Spectrum Disorders; Fetal Development; Folic Acid; Humans; Infant; Micronutrients; Nutritional Status; Pregnancy; Prenatal Nutritional Physiological Phenomena; Vitamin A; Zinc | 2014 |
The relationship between early-life environment, the epigenome and the microbiota.
Topics: Choline; Chromatin; Disease Resistance; DNA Methylation; Epigenesis, Genetic; Fatty Acids, Volatile; Folic Acid; Gene-Environment Interaction; Genome, Human; Histones; Humans; Isothiocyanates; Microbiota; Polyphenols; Probiotics; Protein Processing, Post-Translational | 2015 |
[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy].
Topics: Choline; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Maternal Nutritional Physiological Phenomena; Pregnancy; Pregnancy Complications; Prenatal Nutritional Physiological Phenomena; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
The dynamics of methionine supply and demand during early development.
Topics: Betaine; Child Development; Choline; Creatine; Diet; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Methionine; Phosphatidylcholines | 2016 |
[Research advances in the association between maternal intake of methyl donor nutrients during pregnancy and DNA methylation in offspring].
Topics: Betaine; Choline; DNA Methylation; Female; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Vitamin B 12 | 2017 |
A crucial role for maternal dietary methyl donor intake in epigenetic programming and fetal growth outcomes.
Topics: Animals; Birth Weight; Carbon; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Fetal Development; Fetus; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Nutrients; Placenta; Pregnancy; Vitamin B Complex; Zinc | 2018 |
One-Carbon Metabolism: Biological Players in Epithelial Ovarian Cancer.
Topics: Carbon; Carcinoma, Ovarian Epithelial; Choline; Female; Folic Acid; Humans; Models, Biological; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms | 2018 |
Folate and choline absorption and uptake: Their role in fetal development.
Topics: Animals; Biological Transport, Active; Choline; Eating; Female; Fetal Development; Folic Acid; Humans; Membrane Transport Proteins; Pregnancy | 2019 |
Choline: The Neurocognitive Essential Nutrient of Interest to Obstetricians and Gynecologists.
Topics: Choline; Diet; Female; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy; Vitamins | 2020 |
One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.
Topics: Animals; Betaine; Carbon; Choline; Disease Progression; Female; Folic Acid; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lipid Metabolism; Liver; Methionine; Microbiota; Models, Genetic; Non-alcoholic Fatty Liver Disease; Nutrients; Polymorphism, Single Nucleotide; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2020 |
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methionine; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic; Uremia; Vitamin B 12; Vitamin B 6 | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Choline, folic acid, Vitamin D, and fetal brain development in the psychosis spectrum.
Topics: Brain; Child; Choline; Dietary Supplements; Female; Fetal Development; Folic Acid; Humans; Micronutrients; Pregnancy; Prenatal Care; Psychotic Disorders; Vitamin A; Vitamin D; Vitamins | 2022 |
Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development.
Topics: Animals; Brain; Child Development; Choline; COVID-19; Developmental Disabilities; Dietary Supplements; Fatty Acids, Omega-3; Female; Fetal Development; Fetus; Folic Acid; Humans; Infant; Inflammation; Mothers; Nutritional Requirements; Nutritional Status; Pandemics; Placenta; Pregnancy; Pregnancy Complications, Infectious; SARS-CoV-2; Vitamin D | 2021 |
Prenatal Folate and Choline Levels and Brain and Cognitive Development in Children: A Critical Narrative Review.
Topics: Animals; Brain; Child; Child Development; Child, Preschool; Choline; Cognition; Female; Fetal Development; Folic Acid; Humans; Infant; Male; Mice; Nutritional Status; Pregnancy; Prenatal Nutritional Physiological Phenomena; Surveys and Questionnaires; Vitamins | 2022 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
The role of maternal choline, folate and one-carbon metabolism in mediating the impact of prenatal alcohol exposure on placental and fetal development.
Topics: Carbon; Choline; Female; Fetal Development; Folic Acid; Humans; Maternal-Fetal Exchange; Micronutrients; Placenta; Pregnancy; Prenatal Exposure Delayed Effects | 2023 |
The Role of One-Carbon Metabolism in Healthy Brain Aging.
Topics: Brain; Choline; Dietary Supplements; Folic Acid; Healthy Aging; Humans; Vitamin B 12 | 2023 |
22 trial(s) available for choline and folic acid
| Article | Year |
|---|---|
[Orthopedic and traumatologic clinical experimentation with a heparin preparation].
Topics: Adult; Aged; Choline; Clinical Trials as Topic; Drug Synergism; Female; Folic Acid; Heparin; Humans; Joint Diseases; Lipid Metabolism; Male; Middle Aged; Niacinamide; Thromboembolism; Vitamin B 12 | 1969 |
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors | 1995 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans.
Topics: Adolescent; Adult; Aged; Apoptosis; Biomarkers; Caspase 3; Caspases; Choline; Choline Deficiency; Comet Assay; DNA Damage; Female; Folic Acid; Humans; In Situ Nick-End Labeling; Liver; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Muscle, Skeletal | 2006 |
Sex and menopausal status influence human dietary requirements for the nutrient choline.
Topics: Adolescent; Adult; Aged; Choline; Choline Deficiency; Dose-Response Relationship, Drug; Fatty Liver; Female; Folic Acid; Humans; Male; Menopause; Middle Aged; Muscle, Skeletal; Nutrition Policy; Nutritional Requirements; Phosphatidylcholines; Sex Factors | 2007 |
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex | 2007 |
Folate intake at RDA levels is inadequate for Mexican American men with the methylenetetrahydrofolate reductase 677TT genotype.
Topics: Adult; Choline; Diet; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Genetic Variation; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Nutrition Policy; Vitamin B Complex | 2008 |
Choline status is not a reliable indicator of moderate changes in dietary choline consumption in premenopausal women.
Topics: Adolescent; Adult; Betaine; Choline; Diet; Female; Folic Acid; Genotype; Humans; Liver Diseases; Nutritional Status; Phosphatidylcholines; Premenopause; Sphingomyelins; Treatment Outcome | 2009 |
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult | 2009 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study.
Topics: Aged; Alzheimer Disease; Brain; Choline; Cognitive Dysfunction; Docosahexaenoic Acids; Eicosapentaenoic Acid; Electroencephalography; Folic Acid; Food, Formulated; Humans; Likelihood Functions; Middle Aged; Nerve Net; Phospholipids; Regression Analysis; Selenium; Synapses; Treatment Outcome; Uridine Monophosphate; Vitamins | 2014 |
Postprandial plasma betaine and other methyl donor-related responses after consumption of minimally processed wheat bran or wheat aleurone, or wheat aleurone incorporated into bread.
Topics: Adult; Betaine; Bread; Choline; Cross-Over Studies; Dietary Fiber; Female; Folic Acid; Food Handling; Humans; Male; Postprandial Period; Sarcosine; Seeds; Triticum | 2015 |
Souvenaid reduces behavioral deficits and improves social cognition skills in frontotemporal dementia: a proof-of-concept study.
Topics: Aged; Choline; Cognition; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Executive Function; Female; Folic Acid; Frontotemporal Dementia; Humans; Male; Mental Disorders; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Selenium; Social Skills; Synapses; Treatment Outcome; Uridine Monophosphate | 2015 |
Supplementation with Folic Acid, but Not Creatine, Increases Plasma Betaine, Decreases Plasma Dimethylglycine, and Prevents a Decrease in Plasma Choline in Arsenic-Exposed Bangladeshi Adults.
Topics: Adult; Arsenic; Bangladesh; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Humans; Male; Middle Aged; Sarcosine; Tandem Mass Spectrometry; Vitamin B Complex; Young Adult | 2016 |
Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
Topics: Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Lactation; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylcholines; Polymorphism, Single Nucleotide | 2016 |
One-carbon metabolites and telomere length in a prospective and randomized study of B- and/or D-vitamin supplementation.
Topics: Aged; Biomarkers; Body Mass Index; Calcium Carbonate; Carbon; Choline; Cross-Sectional Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Pilot Projects; Prospective Studies; Sarcosine; Telomere; Telomere Homeostasis; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2017 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial.
Topics: Aged; Betaine; Carbon; Choline; Diet; Diet, High-Protein; Folic Acid; Homocysteine; Humans; Male; Vitamin B Complex | 2021 |
Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women.
Topics: Choline; Cross-Sectional Studies; Diet; Dietary Supplements; Female; Folic Acid; Humans; Iron; Magnesium; Micronutrients; Nutritional Requirements; Potassium; Pregnancy; Pregnant Women; Trace Elements | 2023 |
290 other study(ies) available for choline and folic acid
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12 | 1975 |
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylnitrosamine; Esophageal Neoplasms; Folic Acid; Hemangioendothelioma; Lipotropic Agents; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Nicotinic Acids; Nitrosamines; Rats | 1977 |
Reduction of aflatoxin effects of quail.
Topics: Aflatoxins; Animals; Cholecalciferol; Choline; Folic Acid; Housing, Animal; Leucomycins; Oxytetracycline; Penicillin G Procaine; Poultry Diseases; Pyridoxine; Quail; Streptomycin; Vitamin A; Vitamin B 12; Vitamin E; Vitamin K | 1975 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
A methionine-reversible folate deficiency in rats following the acute administration of diethylnitrosamine and alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Animals; Choline; Diet; Diethylnitrosamine; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Male; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Thiocyanates; Time Factors | 1977 |
[Treatment of vitamin B 12 deficiency].
Topics: Arginine; Aspartic Acid; Choline; Drug Combinations; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intramuscular; Malates; Phosphorylcholine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 1977 |
Effect of vitamin B12 and folate on biosynthesis of methionine from homocysteine in the nematode Caenorhabditis briggsae.
Topics: Animals; Choline; Folic Acid; Homocysteine; Methionine; Nematoda; Vitamin B 12 | 1976 |
Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid.
Topics: Animals; Choline; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Folic Acid Deficiency; Male; Methionine; Nucleotides; Rats; Rats, Inbred F344; Spleen | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error.
Topics: Amino Acids; Anticoagulants; Choline; Coronary Disease; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Pyridoxine; Riboflavin; Vitamin B 12 | 1991 |
Analysis of the pH dependence of folate binding and transport by rat kidney brush border membrane vesicles.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport, Active; Choline; Folic Acid; Hydrogen-Ion Concentration; Kidney; Male; Microvilli; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
Folate deficiency in chicks fed diets containing practical ingredients.
Topics: Animal Feed; Animals; Chickens; Choline; Folic Acid; Folic Acid Deficiency; Glycine max; Liver; Male; Methionine; Poultry Diseases; Weight Gain; Zea mays | 1991 |
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats.
Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine | 1989 |
Folate binding and transport by rat kidney brush-border membrane vesicles.
Topics: Animals; Biological Transport; Choline; Electrochemistry; Folic Acid; Glucose; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Male; Microvilli; Osmolar Concentration; Rats; Rats, Inbred Strains; Sodium Chloride; Tritium | 1988 |
Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis.
Topics: Adult; Anticoagulants; Choline; Coronary Artery Disease; Coronary Disease; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Lipids; Male; Middle Aged; Pyridoxine; Riboflavin; Vitamin B 12 | 1989 |
Muscle creatine content in rats given repeated large doses of nicotinamide: effects of dietary methionine, choline, carnitine, and other supplements.
Topics: Animals; Carnitine; Choline; Creatine; Diet; Folic Acid; Food, Fortified; Histidine; Male; Methionine; Muscles; Niacinamide; Rats; Rats, Inbred Strains; Vitamin B 12 | 1986 |
Generic descriptors and trivial names for vitamins and related compounds.
Topics: 4-Aminobenzoic Acid; Ascorbic Acid; Avitaminosis; Biotin; Choline; Folic Acid; Inositol; Niacin; Pantothenic Acid; Pyridoxine; Terminology as Topic; Thiamine; Thioctic Acid; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamin K; Vitamins | 1986 |
Excitotoxic mechanisms of epileptic brain damage.
Topics: Administration, Topical; Amygdala; Animals; Axons; Biomechanical Phenomena; Brain; Choline; Cholinesterase Inhibitors; Convulsants; Corpus Striatum; Epilepsy; Folic Acid; Injections; Kainic Acid; Lithium; Motor Cortex; Neural Pathways; Neurotoxins; Piperidines; Rats; Seizures; Somatosensory Cortex | 1986 |
A comparison of the response of woodchucks and rats to variations in dietary lipotrope and lipid content.
Topics: Animals; Blood Cell Count; Body Weight; Choline; Diet; Dietary Fats; Folic Acid; Liver; Liver Function Tests; Male; Marmota; Methionine; Organ Size; Rats; Rats, Inbred F344; Sciuridae; Vitamin B 12 | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
Lipotropic activity of inositol and chlortetracycline alone and in various combinations of choline, vitamin B 12 and folic acid. Activity of three liver extracts with assays for these substances.
Topics: Animals; Body Weight; Cattle; Chlortetracycline; Choline; Dietary Fats; Drug Combinations; Fatty Liver; Folic Acid; Inositol; Lipids; Lipotropic Agents; Liver; Liver Extracts; Male; Organ Size; Rats; Vitamin B 12 | 1971 |
Lipotropic factors for beef cattle fed high-concentrate diets.
Topics: Animal Feed; Animals; Body Weight; Cattle; Choline; Diet; Female; Folic Acid; Injections, Intraperitoneal; Inositol; Lipids; Lipotropic Agents; Liver; Male; Niacinamide; Phospholipids; Vitamin B 12 | 1974 |
Qualitative vitamin requirements of Oryzaephilus mercator fauvel and their deficiency effects on the survival and growth of F1-progeny.
Topics: Aminobenzoates; Animals; Biotin; Choline; Female; Folic Acid; Inositol; Insecta; Larva; Male; Metamorphosis, Biological; Nicotinic Acids; Pantothenic Acid; Pupa; Pyridoxine; Reproduction; Riboflavin; Thiamine; Vitamins | 1974 |
Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats.
Topics: Animals; Betaine; Carcinogens; Choline; Diet; Drinking; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamates; Histidine; Liver; Male; Methionine; Nitrosamines; Rats; Stimulation, Chemical; Transferases; Urocanate Hydratase; Vitamin B 12 | 1973 |
Influence of short-term alcohol consumption on the excretion of some components of the vitamin-B group in the urine of rats.
Topics: Alcoholism; Animals; Biological Assay; Biotin; Choline; Ethanol; Feces; Female; Fluorometry; Folic Acid; Humans; Lipotropic Agents; Male; Methionine; Niacinamide; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Rats; Thiamine; Vitamin B Complex | 1967 |
Vitamins and growth factors in the nutrition of rabbit blastocysts in vitro.
Topics: Animals; Ascorbic Acid; Biotin; Choline; Embryo, Mammalian; Female; Folic Acid; Hypoxanthines; In Vitro Techniques; Inositol; Niacinamide; Nutritional Physiological Phenomena; Ovum; Pantothenic Acid; Pyridoxine; Rabbits; Riboflavin; Thiamine; Thymidine; Vitamin A; Vitamin B 12; Vitamin B Complex; Vitamin D; Vitamin E; Vitamins | 1967 |
[Clinical evaluation of a new preparation with liver-protective and anti-anemic action].
Topics: Adolescent; Adult; Aged; Anemia; Choline; Female; Folic Acid; Hemochromatosis; Humans; Hydroxybutyrates; Liver Diseases; Male; Middle Aged; Niacinamide; Phosphoric Acids; Pyridoxine; Vitamin B 12 | 1966 |
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Development; Estrus; Female; Fertility; Fetal Death; Folic Acid; Formaldehyde; Glycine; Growth; Hernia, Umbilical; Hydrocephalus; Kidney Cortex Necrosis; Male; Niacinamide; Nutritional Requirements; Oxidation-Reduction; Pregnancy; Rats; Reproduction; Sarcosine; Spinal Dysraphism; Vitamin B 12 | 1970 |
[On the comparative results of the use of Clarisco in peripheral vascular diseases].
Topics: Aged; Arteriosclerosis Obliterans; Choline; Coronary Disease; Folic Acid; Gangrene; Heparin; Humans; Male; Middle Aged; Niacinamide; Sympathectomy; Thrombosis; Vascular Diseases; Vasodilator Agents; Vitamin B 12 | 1970 |
The uptake of vitamins by mouse fibroblast cells (strain LS) during growth in a chemically defined medium.
Topics: Animals; Biological Assay; Biotin; Cell Line; Choline; Culture Media; Culture Techniques; Fibroblasts; Folic Acid; Hypoxanthines; Inositol; Mice; Niacinamide; Pantothenic Acid; Riboflavin; Thiamine; Vitamin B 12; Vitamins | 1971 |
Tentative rules for generic descriptors and trivial names for vitamins and related compounds.
Topics: Aminobenzoates; Ascorbic Acid; Biotin; Carotenoids; Choline; Folic Acid; Inositol; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Terminology as Topic; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamin K; Vitamins | 1971 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
Composition and properties of whey protein concentrates from ultrafiltration.
Topics: Amino Acids; Cheese; Choline; Dairy Products; Folic Acid; Food-Processing Industry; Hot Temperature; Hydrogen-Ion Concentration; Industrial Waste; Lactose; Milk Proteins; Minerals; Nicotinic Acids; Pantothenic Acid; Riboflavin; Solubility; Thiamine; Ultrafiltration | 1974 |
A patient with nonketotic hyperglycinemia: biochemical findings and therapeutic approaches.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Benzoates; Biopsy; Carbon Radioisotopes; Child, Preschool; Choline; Diet Therapy; Electroencephalography; Female; Folic Acid; Glycine; Humans; Infant; Infant, Newborn; Leucovorin; Liver; Methionine; Pyridoxine; Salicylates; Tetrahydrofolates | 1974 |
Vitamin and mineral allowances.
Topics: Ascorbic Acid; Biotin; Calcium; Chlorine; Choline; Folic Acid; Humans; Magnesium; Minerals; Nicotinic Acids; Nutritional Physiological Phenomena; Nutritional Requirements; Pantothenic Acid; Phosphorus; Potassium; Pyridoxine; Riboflavin; Sodium; Thiamine; Trace Elements; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamin K; Vitamins | 1972 |
Schildt B, Sörbo B,+SORBO B:Studies on the biosynthesis and transfer of labile methyl groups in experimental burns.
Topics: Animals; Burns; Choline; Folic Acid; Liver; Methionine; Methylation; Mice; Vitamin B 12 | 1973 |
Vitamin contents of arterial tissue.
Topics: Aminobenzoates; Animals; Arteries; Arteriosclerosis; Ascorbic Acid; Biotin; Carotenoids; Chickens; Choline; Dogs; Folic Acid; Humans; Inositol; Nicotinic Acids; Pyridoxine; Rabbits; Riboflavin; Thiamine; Vitamin A; Vitamin B 12; Vitamin E; Vitamins | 1973 |
[The treatment of gastrointestinal disorders with Enzymed].
Topics: Amylases; Ascorbic Acid; Choline; Delayed-Action Preparations; Enzyme Therapy; Folic Acid; Gastrointestinal Diseases; Humans; Pancreatin; Pepsin A; Riboflavin; Thiamine; Vitamins | 1968 |
[Therapeutic progress in chronic liver diseases].
Topics: Choline; Chronic Disease; Folic Acid; Hepatitis; Humans; Liver Cirrhosis; Orotic Acid; Thioctic Acid; Vitamin B 12 | 1968 |
Nomenclature policy: generic descriptors and trivial names for vitamins and related compounds.
Topics: Aminobenzoates; Ascorbic Acid; Biotin; Carotenoids; Chemical Phenomena; Chemistry; Choline; Folic Acid; Inositol; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Riboflavin; Solubility; Terminology as Topic; Thiamine; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamin K; Vitamins | 1972 |
Function and control of liver alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Bile; Cell Membrane; Cell Nucleus; Choline; DNA Replication; Drug Synergism; Fatty Acids; Female; Folic Acid; Glycine; Heparin; Hepatectomy; Hydrocortisone; Liver; Liver Regeneration; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Rats; Serine; Solubility | 1972 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency | 1972 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays | 1971 |
Effect of certain vitamins on the growth and sporulation of Curvularia lunata (Wakker) Boedijn.
Topics: Biotin; Choline; Culture Media; Folic Acid; Inositol; Mitosporic Fungi; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Riboflavin; Spores; Spores, Fungal; Thiamine; Vitamins | 1971 |
Vitamin E response in infants fed a low-fat formula.
Topics: Anemia, Hemolytic; Blood Proteins; Body Weight; Choline; Creatine; Creatine Kinase; Creatinine; Folic Acid; Hemoglobins; Hemolysis; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Injections, Intramuscular; Malonates; Reticulocytes; Serum Albumin; Vitamin B 12; Vitamin E | 1968 |
[New studies on intervitamin correlations. VI. Correlative relationship between L-ascorbic acid and five vitamin factors of the B complex in guinea pigs (folic and pantothenic acids, choline, pyridoxine, cyanocobalamin)].
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Choline; Drug Synergism; Folic Acid; Guinea Pigs; Male; Pantothenic Acid; Pyridoxine; Vitamin B 12; Vitamin B Complex | 1968 |
[Study on the requirements of an insect cell line (EPa strain). II. Hydrosoluble vitamins].
Topics: Animals; Choline; Culture Techniques; Folic Acid; Inositol; Insecta; Pantothenic Acid; Vitamin B 12; Vitamins | 1969 |
Relation of vitamin B12 and one-carbon metabolism to hydrocephalus in the rat.
Topics: Animals; Animals, Newborn; Carbon; Choline; Diet; Folic Acid; Folic Acid Antagonists; Hydrocephalus; Methionine; Rats; Vitamin B 12 Deficiency | 1966 |
The biosynthesis of the methyl groups of choline in Ochromonas malhamensis.
Topics: Alkylation; Amino Alcohols; Choline; Eukaryota; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Microsomes; Mitochondria; Nucleosides; Phosphatidylcholines; Subcellular Fractions; Vitamin B 12 | 1966 |
Determination of some water-soluble vitamin levels in Planorbidae.
Topics: Aminobenzoates; Biotin; Choline; Folic Acid; Nicotinic Acids; Pyridoxine; Snails; Vitamin B 12; Vitamin B Complex | 1966 |
Vitamin B12 deficiency in the rat: effect on serum folate and liver formiminotransferase activity.
Topics: Aldehyde-Lyases; Animals; Biological Assay; Choline; Folic Acid; Glutamates; Liver; Male; Methionine; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1967 |
Effect of vitamin B-12 in choline deficiency in the rat.
Topics: Amino Acids; Animals; Body Weight; Choline; Choline Deficiency; Diet; FIGLU Test; Folic Acid; Growth; Hematocrit; Hemoglobins; Kidney; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Rats; Vitamin B 12; Vitamin B Deficiency | 1967 |
Nonketotic hyperglycinemia: treatment with diazepam--a competitor for glycine receptors.
Topics: Binding, Competitive; Choline; Diazepam; Electroencephalography; Female; Folic Acid; Glycine; Humans; Infant, Newborn; Receptors, Cell Surface; Receptors, Glycine; Seizures | 1983 |
A minimal medium for the cultivation of infective Trypanosoma cruzi epimastigotes.
Topics: Animals; Catalase; Choline; Culture Media; Folic Acid; Glucose; Host-Parasite Interactions; Hydrogen-Ion Concentration; Mice; Microscopy, Electron; Rhodnius; Salts; Trypanosoma cruzi | 1983 |
Relationship between nutrition and dementia in the elderly.
Topics: Acetylcholine; Aged; Aged, 80 and over; Aging; Aluminum; Choline; Cognition; Dementia; Folic Acid; Humans; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Psychoses, Alcoholic; Thiamine Deficiency; Vitamin B 12 | 1983 |
Trypanosoma cruzi: nucleotide and vitamin requirements of growing epimastigotes.
Topics: Animals; Choline; Culture Media; Folic Acid; Nucleotides; Trypanosoma cruzi; Vitamins | 1981 |
The folic acid requirements of starting broiler chicks fed diets based on practical ingredients. 1. Interrelationships with dietary choline.
Topics: Animals; Body Weight; Bone and Bones; Chickens; Choline; Folic Acid; Food, Fortified; Male; Nutritional Requirements; Osteochondrodysplasias; Tibia | 1995 |
Modulation of expression of fos and Ha-ras oncogenes and ornithine decarboxylase activity in mammary gland and liver of young female rats by the absence of dietary lipotropes.
Topics: Animals; Choline; Choline Deficiency; Diet; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genes, fos; Genes, ras; Liver; Mammary Glands, Animal; Methionine; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency | 1994 |
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver.
Topics: Animals; Body Weight; Choline; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Phosphorylcholine; Rats; Rats, Sprague-Dawley | 1994 |
Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
Topics: Adult; Choline; Diet; Folic Acid; Folic Acid Deficiency; Glycine max; Homocysteine; Humans; Male; Methionine; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12 | 1994 |
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12 | 1993 |
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats.
Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar | 1995 |
Lipotrope-mediated c-jun and ornithine decarboxylase mRNA expression in mammary acinar cells.
Topics: Animals; Choline; Female; Folic Acid; Gene Expression; Genes, jun; Mammary Glands, Animal; Methionine; Ornithine Decarboxylase; Rats; RNA, Messenger; Vitamin B 12 | 1996 |
Brain folates and DNA methylation in rats fed a choline deficient diet or treated with low doses of methotrexate.
Topics: Animals; Brain; Choline; Choline Deficiency; Diet; DNA Methylation; Folic Acid; Male; Methotrexate; Rats; Rats, Wistar | 1996 |
Use of 13C nuclear magnetic resonance to evaluate metabolic flux through folate one-carbon pools in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Choline; Folic Acid; Formates; Glycine; Leucovorin; Magnetic Resonance Spectroscopy; Purines; Saccharomyces cerevisiae; Serine | 1997 |
Translating the science behind the Dietary Reference Intakes.
Topics: Adolescent; Adult; Calcium, Dietary; Child; Choline; Folic Acid; Humans; Middle Aged; Nutrition Policy; Phosphorus, Dietary; United States; Vitamin B 12; Vitamin D | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline.
Topics: Animals; Choline; Diet; DNA Methylation; Folic Acid; Methionine; Mice; Rats | 2002 |
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning | 2002 |
A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro.
Topics: Adult; Biological Availability; Carrier Proteins; Cell Division; Cells, Cultured; Choline; Chromosome Breakage; Chromosomes, Human; Deoxyuracil Nucleotides; DNA; DNA Damage; DNA Methylation; DNA Replication; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lymphocyte Activation; Lymphocytes; Membrane Transport Proteins; Methionine; Micronucleus Tests; Middle Aged; Oxidation-Reduction; Phytohemagglutinins; Prodrugs; Receptors, Cell Surface; Reduced Folate Carrier Protein; Tetrahydrofolates; Uracil | 2003 |
Transposable elements: targets for early nutritional effects on epigenetic gene regulation.
Topics: Alleles; Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; DNA Transposable Elements; Exons; Folic Acid; Gene Expression Regulation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Genetic; Molecular Sequence Data; Nutritional Physiological Phenomena; Phenotype; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Vitamin B 12 | 2003 |
Effects of reducing dietary protein, methionine, choline, folic acid, and vitamin B12 during the late stages of the egg production cycle on performance and eggshell quality.
Topics: Animal Feed; Animal Husbandry; Animals; Chickens; Choline; Dietary Proteins; Egg Shell; Female; Folic Acid; Methionine; Ovum; Vitamin B 12 | 2003 |
The synthesis of choline and creatine in rats under various dietary conditions.
Topics: Animals; Choline; Creatine; Creatinine; Diet; Folic Acid; Folic Acid Deficiency; Rats; Vitamin B 12 Deficiency | 1953 |
Non-participation of folic acid in the biosynthesis of methyl compounds from precursors.
Topics: Biochemical Phenomena; Choline; Coenzymes; Folic Acid; Methionine | 1954 |
Water-soluble vitamins. I. Folic acid, B12, CF, choline, PAB, biotin.
Topics: Biotin; Choline; Folic Acid; Vitamins | 1954 |
The effect of folic acid deficiency on the metabolism of choline by chick bone marrow.
Topics: Animals; Bone Marrow; Chickens; Choline; Folic Acid; Folic Acid Deficiency; Humans | 1954 |
Water-soluble vitamins. I. Vitamin B12, folic acid, choline, and para-aminobenzoic acid.
Topics: 4-Aminobenzoic Acid; Choline; Folic Acid; Vitamin B 12; Vitamins | 1955 |
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 1957 |
Antagonism of gamma-butyrobetaine and carnitine on chick embryonic bones cultivated in vitro.
Topics: Animals; Betaine; Bone and Bones; Carnitine; Chickens; Choline; Folic Acid; In Vitro Techniques; Vitamin B Complex | 1957 |
[Antagonism of gamma-butyrobetaine and carnitine in bone skeleton cultivated in vitro].
Topics: Betaine; Bone and Bones; Carnitine; Choline; Embryo, Mammalian; Embryo, Nonmammalian; Folic Acid; In Vitro Techniques; Vitamin B Complex | 1957 |
Effects of choline deficiency and carnitine on palmitic acid oxidation by rat liver homogenates.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Fatty Acids; Folic Acid; Lipid Metabolism; Liver; Oxidation-Reduction; Palmitic Acid; Rats; Ventricular Fibrillation; Vitamin B Complex | 1957 |
Ineffectiveness of carnitine as a choline substitute in the prevention of fatty livers of rats maintained on a choline-deficient diet.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Diet; Fatty Liver; Folic Acid; Rats; Vitamin B Complex | 1957 |
Water-soluble vitamins. I. Vitamin B12, folic acid, choline, and para-aminobenzoic acid.
Topics: 4-Aminobenzoic Acid; Choline; Folic Acid; Vitamin B 12; Vitamins | 1957 |
Water-soluble vitamins. I. Folic acid, B12 group, choline.
Topics: Choline; Folic Acid; Vitamin B 12; Vitamins | 1958 |
[Clinical experimentation on a preparation with antisclerogenous action].
Topics: Arteriosclerosis; Choline; Folic Acid; Heparin; Humans; Vitamin B Complex | 1959 |
Methionine, homocystine, choline, folic acid and vitamin B12 in the nutrition of the mouse.
Topics: Animals; Choline; Cystine; Folic Acid; Homocystine; Humans; Methionine; Mice; Nutritional Status; Vitamin B 12 | 1959 |
Effect of dietary deficiencies of folic acid and choline on lipid metabolism in the rat.
Topics: Animals; Choline; Choline Deficiency; Folic Acid; Folic Acid Deficiency; Lipid Metabolism; Lipids; Rats | 1960 |
[On the treatment of skin diseases associated with liver disorders].
Topics: Choline; Folic Acid; Humans; Liver Diseases; Methionine; Skin Diseases; Vitamin B Complex | 1961 |
[The influence of gama-butyrobetaine, crotonic acid betaine and isomeric carnitine on the growth of a mouse sarcoma].
Topics: Animals; Betaine; Carnitine; Choline; Folic Acid; Sarcoma, Experimental; Vitamin B Complex | 1962 |
Studies on a beta-methylcholine-containing phospholipid derived from carnitine.
Topics: Carnitine; Choline; Folic Acid; Phospholipids; Vitamin B Complex | 1963 |
Chromatography of quaternary nitrogen compounds on buffered cation-exchange resins.
Topics: Buffers; Cation Exchange Resins; Cations; Choline; Chromatography; Folic Acid; Niacin; Niacinamide; Nitrogen; Nitrogen Compounds; Vitamin B Complex | 1963 |
PANTETHINE-REQUIRING BACTEROIDES.
Topics: Bacteroides; Biotin; Choline; Coenzyme A; Culture Media; Entamoeba histolytica; Folic Acid; Pantetheine; Pyridoxine; Research; Spectrophotometry; Thiamine | 1963 |
[THE TRIBOLIUM TEST AS A QUANTITATIVE TEST FOR 8 B-VITAMINS].
Topics: Animals; Chemistry, Pharmaceutical; Choline; Folic Acid; Humans; Pantothenic Acid; Thiamine; Tribolium; Vitamin B Complex; Vitamins | 1963 |
[PROBLEMS IN DRUG THERAPY AND ATHEROSCLEROSIS PREVENTION].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Fatty Acids; Folic Acid; Hematinics; Humans; Lipid Metabolism; Lipotropic Agents; Niacin; Nicotinic Acids; Proteins; Pyridoxine; Vitamin B 12 | 1963 |
EFFECT OF WATER SOLUBLE VITAMINS AND THEIR ANALOGUES ON GROWTH OF CANDIDA ALBICANS. III. PARA-AMINOBENZOIC ACID, NICOTINIC ACID, INOSITOL AND THEIR ANALOGUES.
Topics: 4-Aminobenzoic Acid; Ascorbic Acid; Biotin; Candida; Candida albicans; Choline; Corrinoids; Culture Media; Folic Acid; Inositol; Metabolism; Niacin; Nicotinic Acids; Pantothenic Acid; Pharmacology; Pyridines; Research; Riboflavin; Sulfisoxazole; Sulfonic Acids; Thiamine; Thioctic Acid; Vitamin B 12; Vitamin B Complex; Vitamins | 1964 |
ACTIONS OF BETAINE, CARNITINE AND CHOLINE ON THE PATTERN OF HEPATIC LIPOSIS IN MICE FED A HIGH-FAT, LOW-PROTEIN DIET.
Topics: Animals; Betaine; Carnitine; Choline; Diet, High-Fat; Diet, Protein-Restricted; Dietary Fats; Dietary Proteins; Folic Acid; Lipid Metabolism; Lipidoses; Lipotropic Agents; Liver; Liver Diseases; Mice; Pathology; Research; Statistics as Topic; Vitamin B Complex | 1964 |
PROULX P: ACETYLCHOLINE-LIKE ACTIVITY IN SUBCELLULAR PARTICLES ISOLATED FROM RAT BRAIN.
Topics: Acetylcholine; Animals; Anura; Biological Assay; Brain; Brain Chemistry; Choline; Chromatography; Folic Acid; Physostigmine; Rats; Research; Tissue Extracts; Ultraviolet Rays; Vitamin B Complex | 1964 |
THE CHOLINOMIMETIC ACTIVITY OF EXTRACTS OF BRAIN NERVE TERMINALS.
Topics: Acetylcholine; Amines; Biological Assay; Brain; Brain Chemistry; Carnitine; Choline; Cholinergic Agents; Chromatography; Electrophoresis; Folic Acid; Mitochondria; Muscle, Smooth; Muscles; Myocardium; Nerve Endings; Physostigmine; Research; Tissue Extracts; Vitamin B Complex | 1964 |
STUDIES IN PHOSPHOLIPID METABOLISM. I. EFFECT OF GUANIDOACETIC ACID AND CHOLINE ON LIVER PHOSPHOLIPIDS.
Topics: Acetates; Choline; Folic Acid; Glycine; Guanidines; Lecithins; Lipid Metabolism; Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Research; Vitamin B 12 | 1964 |
[THE VARIOUS FORMS OF HEPATIC COMA AND THEIR TREATMENT].
Topics: Adrenal Cortex Hormones; Anti-Infective Agents, Local; Choline; Drug Therapy; Folic Acid; Fructose; Hepatic Encephalopathy; Humans; Vitamin B Complex | 1965 |
LIPOTROPIC ACTIVITY OF CHOLINE, VITAMINS B12 AND B-126, FOLIC ACID, AND CITROVORUM FACTOR.
Topics: Body Weight; Choline; Dietary Fats; Folic Acid; Leucovorin; Lipotropic Agents; Liver; Organ Size; Pharmacology; Rats; Research; Vitamin B 12; Vitamin B Complex; Vitamins | 1965 |
CARNITINE ACETYLTRANSFERASE. II. INHIBIITON BY CARNITINE ANALOGUES AND BY SULFHYDRYL REAGENTS.
Topics: Acyltransferases; Aminobutyrates; Benzoates; Carnitine; Carnitine O-Acetyltransferase; Choline; Coenzyme A; Edrophonium; Enzyme Inhibitors; Folic Acid; Mercaptoethanol; Neostigmine; Neuromuscular Nondepolarizing Agents; Research; Sulfhydryl Reagents; Vitamin B Complex | 1965 |
FOLIC ACID DEFICIENCY AND HEMOCHROMATOSIS.
Topics: Blood Chemical Analysis; Choline; Diet; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemochromatosis; Iron; Lipotropic Agents; Liver; Neomycin; Pancreas; Pantothenic Acid; Pharmacology; Pyridoxine; Rats; Research; Sucrose; Vitamin B 12; Vitamin B Complex | 1965 |
THE EFFECTS OF CHOLINE AND RELATED COMPOUNDS ON THE GROWTH AND DEVELOPMENT OF DROSOPHILA MELANOGASTER.
Topics: Amino Acids; Amino Alcohols; Ammonium Compounds; Animals; Betaine; Carnitine; Chemical Phenomena; Chemistry; Choline; Diet; Drosophila; Drosophila melanogaster; Fatty Liver; Folic Acid; Growth and Development; Meat; Metamorphosis, Biological; Methionine; Neurospora; Pharmacology; Poultry; Quaternary Ammonium Compounds; Rats; Research; Salts; Vitamin B Complex | 1965 |
SOME PHYSIOLOGICAL AND BIOCHEMICAL PROPERTIES OF ACETYL-L-CARNITINE ISOLATED FROM BRAIN TISSUE EXTRACTS.
Topics: Acetylcarnitine; Acetylcholine; Ammonium Compounds; Animals; Brain; Brain Chemistry; Carnitine; Cattle; Chemical Phenomena; Chemistry, Physical; Choline; Chromatography; Crystallization; Folic Acid; Physical Examination; Quaternary Ammonium Compounds; Research; Tissue Extracts; Vitamin B Complex | 1964 |
THE IDENTIFICATION OF THE ACETYLCHOLINE-LIKE SUBSTANCE IN SYNATOSOMES DERIVED FROM GUINEA-PIG BRAIN AS ACETYLCHOLINE ITSELF.
Topics: Acetylcholine; Animals; Biological Assay; Brain; Brain Chemistry; Carnitine; Choline; Chromatography; Folic Acid; Guinea Pigs; Muscles; Research; Ultracentrifugation; Vitamin B Complex | 1964 |
The effect of substituting carnitine for choline in the nutrition of several organisms.
Topics: Animals; Carnitine; Choline; Folic Acid; Insecta; Neurospora; Vitamin B Complex | 1955 |
The chick's requirement for folic acid in the utilization of choline and its precursors betaine and methylaminoethanol.
Topics: Animals; Betaine; Chickens; Choline; Folic Acid; Humans; Meat; Poultry | 1955 |
The determination of choline in the presence of B complex vitamins.
Topics: Choline; Folic Acid; Health Services; Vitamin B Complex; Vitamins | 1951 |
Choline requirement of rats as influenced by age, strain, vitamin B12 and folacin.
Topics: Animals; Choline; Corrinoids; Folic Acid; Hematinics; Rats; Vitamin B 12 | 1951 |
Influence of vitamin B12 and folacin on the synthesis of choline and methionine by the rat.
Topics: Animals; Biochemical Phenomena; Choline; Corrinoids; Folic Acid; Hematinics; Methionine; Rats; Vitamin B 12 | 1951 |
The relation of vitamin B12 and folacin to the utilization of choline and its precursors for lipotropism and renal protection in rats.
Topics: Animals; Choline; Folic Acid; Kidney; Lipotropic Agents; Rats; Vitamin B 12 | 1951 |
[Contribution to the study of pellagra].
Topics: Choline; Folic Acid; Humans; Methionine; Pellagra; Vitamin B Complex | 1951 |
Vitamin B12 and folic acid in the synthesis of choline in the rat.
Topics: Animals; Biochemical Phenomena; Choline; Folic Acid; Humans; Rats; Vitamin B 12 | 1952 |
Sex-related differences in effect of ethanol administration and folic acid supplementation on pancreatic amylase in rats.
Topics: Amylases; Animals; Body Weight; Central Nervous System Depressants; Choline; Dietary Supplements; Ethanol; Female; Folic Acid; Hematinics; Lactation; Male; Maternal-Fetal Exchange; Organ Size; Pancreas; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sex Factors | 2004 |
Interrelationship of folacin, vitamin B12 and choline; effect on hemorrhagic kidney syndrome in the rat and on growth of the chick.
Topics: Animals; Chickens; Choline; Folic Acid; Humans; Kidney; Kidney Diseases; Rats; Vitamin B 12; Vitamin B Complex | 1950 |
The requirements of poultry for aneurin, choline, folic acid, nicotinic acid, pantothenic acid and riboflavin.
Topics: Animals; Choline; Folic Acid; Meat; Niacin; Nicotinic Acids; Pantothenic Acid; Poultry; Riboflavin; Thiamine | 1949 |
A relationship of folic acid to choline oxidase.
Topics: Alcohol Oxidoreductases; Choline; Coloring Agents; Folic Acid; Humans; Oxidoreductases; Peroxidase; Peroxidases | 1949 |
The inhibition of chicken-bone marrow choline oxidase by aminopterin in vivo.
Topics: Alcohol Oxidoreductases; Aminopterin; Animals; Bone Marrow; Chickens; Choline; Coloring Agents; Folic Acid; Meat; Oxidoreductases; Peroxidase; Peroxidases | 1950 |
VITAMIN B12, folic acid, and choline interrelations.
Topics: Choline; Folic Acid; Humans; Vitamin B 12; Vitamin B Complex | 1950 |
[Treatment of toxic granulocytopenia].
Topics: Agranulocytosis; Choline; Folic Acid; Humans; Vitamin B 6 | 1950 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans.
Topics: Adult; Aged; Carbon; Choline; Choline Deficiency; Female; Folic Acid; Genetic Predisposition to Disease; Heterozygote; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Premenopause | 2005 |
Fat-soluble and water-soluble vitamin contents of breast milk from Japanese women.
Topics: Ascorbic Acid; Biotin; Cholecalciferol; Choline; Fats; Female; Folic Acid; Humans; Inositol; Japan; Lactation; Milk, Human; Niacin; Pantothenic Acid; Seasons; Solubility; Time Factors; Vitamin A; Vitamin B Complex; Vitamin E; Vitamins; Water | 2005 |
[The effect of methyl-containing supplements during pregnancy on the phenotypic modification of offspring hair color in rats].
Topics: Agouti Signaling Protein; Animals; Betaine; Choline; Color; Dietary Supplements; Electron Spin Resonance Spectroscopy; Female; Folic Acid; Hair Color; Heterozygote; Homozygote; Intercellular Signaling Peptides and Proteins; Male; Methionine; Phenotype; Pigments, Biological; Pregnancy; Rats; Vitamin B 12; Zinc | 2006 |
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Sex Factors; Surveys and Questionnaires; Vitamin B Complex | 2006 |
Modification of p53 protein profile by gamma irradiation followed by methyl donor starvation.
Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Liver; Male; Methionine; Mice; Spleen; Thymus Gland; Tumor Suppressor Protein p53 | 2006 |
Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation.
Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; S-Adenosylmethionine | 2007 |
Maternal methyl supplements increase offspring DNA methylation at Axin Fused.
Topics: Alleles; Animals; Axin Protein; Betaine; Body Weight; Choline; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation; Heterozygote; Introns; Mice; Mice, Inbred C57BL; Models, Genetic; Polymerase Chain Reaction; Pregnancy; Random Allocation; Repressor Proteins; Sulfites; Vitamin B 12 | 2006 |
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors | 2006 |
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2007 |
Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women.
Topics: Aged; Betaine; Cardiovascular Diseases; Choline; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Netherlands; Nutrition Surveys; Odds Ratio; Postmenopause; Prospective Studies; Surveys and Questionnaires | 2008 |
Folate deficiency during pregnancy impacts on methyl metabolism without affecting global DNA methylation in the rat fetus.
Topics: Amino Acids; Animals; Choline; Diet; DNA Methylation; Female; Fetus; Folic Acid; Folic Acid Deficiency; Liver; Maternal-Fetal Exchange; Metabolic Networks and Pathways; Methionine; Phosphorylcholine; Pregnancy; Pregnancy Complications; Rats; Weight Gain | 2007 |
Consumption of folate-related nutrients and metabolism of arsenic in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Choline; Cysteine; Dietary Proteins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Niacin; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
Folate intake and the MTHFR C677T genotype influence choline status in young Mexican American women.
Topics: Adolescent; Adult; Betaine; Choline; Diet; Dietary Supplements; Female; Folic Acid; Genotype; Hispanic or Latino; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Nutritional Status; Phosphatidylcholines; Sphingomyelins | 2008 |
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution.
Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine | 2007 |
Reduction of Excess Acetylcholine in the Serum of Pernicious Anemia Patients by Treatment With Pteroyl Glutamic Acid, Liver Extract, or Ventriculin.
Topics: Acetylcholine; Anemia; Anemia, Pernicious; Blood; Choline; Folic Acid; Glutamates; Liver; Liver Extracts; Tracheophyta; Vitamin B Complex; Vitamins | 1946 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Ethnicity and folate influence choline status in young women consuming controlled nutrient intakes.
Topics: Adolescent; Adult; Betaine; Black or African American; Body Mass Index; Choline; Diet; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sphingomyelins; White People | 2008 |
Interaction between cytotoxic effects of gamma-radiation and folate deficiency in relation to choline reserves.
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Animals; Brain Chemistry; Choline; DNA; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Eating; Folic Acid; Folic Acid Deficiency; Gamma Rays; Indicators and Reagents; Kidney; Liver; Male; Mice; Phosphatidylcholines; Tetrahydrofolate Dehydrogenase | 2009 |
Hypospadias and intake of nutrients related to one-carbon metabolism.
Topics: Carbon; Choline; Diet; Dietary Supplements; Female; Folic Acid; Humans; Hypospadias; Infant, Newborn; Male; Methionine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Riboflavin; Thiamine; Vitamin B 12; Vitamin B 6; Zinc | 2009 |
Dietary patterns, food groups, and nutrients as predictors of plasma choline and betaine in middle-aged and elderly men and women.
Topics: Aged; Betaine; Bread; Cardiovascular Diseases; Choline; Cohort Studies; Diet Surveys; Dietary Fats; Eggs; Factor Analysis, Statistical; Feeding Behavior; Female; Folic Acid; Food, Fortified; Humans; Linear Models; Male; Meat; Metabolic Syndrome; Middle Aged; Norway; Phospholipids | 2008 |
Tissue methionine cycle activity and homocysteine metabolism in female rats: impact of dietary methionine and folate plus choline.
Topics: Animals; Body Composition; Choline; Diet; Dietary Proteins; Female; Folic Acid; Homocysteine; Methionine; Models, Biological; Rats; Tissue Distribution | 2009 |
Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted.
Topics: Adolescent; Adult; Biomarkers; Choline; Dose-Response Relationship, Drug; Female; Folic Acid; Folic Acid Deficiency; Genetic Variation; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mexican Americans; Nutritional Status; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Premenopause; Young Adult | 2009 |
Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers.
Topics: Adenocarcinoma; Case-Control Studies; Choline; Diet; DNA Methylation; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Polymorphism, Restriction Fragment Length; Risk Factors; Stomach Neoplasms; Vitamin B 6 | 2009 |
[Methyl-containing diet of mothers affects the AGOUTI gene expression in the offspring of rats with various behavioral types].
Topics: Aggression; Agouti Signaling Protein; Animals; Behavior, Animal; Betaine; Choline; Dietary Supplements; Female; Folic Acid; Hair Color; Methionine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selection, Genetic; Species Specificity; Vitamin B 12; Zinc | 2009 |
Choline and risk of neural tube defects in a folate-fortified population.
Topics: Adult; California; Choline; Dietary Supplements; Female; Folic Acid; Humans; Lipotropic Agents; Neural Tube Defects; Odds Ratio; Prospective Studies; Risk Assessment; Young Adult | 2009 |
Associations of folate and choline metabolism gene polymorphisms with orofacial clefts.
Topics: Betaine-Homocysteine S-Methyltransferase; Choline; Choline-Phosphate Cytidylyltransferase; Cleft Lip; Cleft Palate; Databases, Genetic; Epistasis, Genetic; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Metabolic Networks and Pathways; Polymorphism, Single Nucleotide | 2010 |
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gamma Rays; Homocysteine; Male; Mice; S-Adenosylmethionine; Time Factors | 2010 |
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.
Topics: Animals; Body Weight; Cell Lineage; Choline; Deficiency Diseases; Enteroendocrine Cells; Female; Fetal Development; Folic Acid; Gastric Mucosa; Ghrelin; Growth Hormone; Homocysteine; Immunohistochemistry; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Weaning | 2010 |
Choline and betaine intake and risk of breast cancer among post-menopausal women.
Topics: Adult; Aged; Aged, 80 and over; Betaine; Breast Neoplasms; Choline; Female; Folic Acid; Humans; Middle Aged; Postmenopause; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Risk | 2010 |
CpG methylation of a silent controlling element in the murine Avy allele is incomplete and unresponsive to methyl donor supplementation.
Topics: Agouti Signaling Protein; Alleles; Animals; Base Sequence; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genes, Intracisternal A-Particle; Germ Cells; Male; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Insertional; Phenotype; Promoter Regions, Genetic; Retroelements | 2010 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
The influence of environmental temperature on dietary requirement for thiamine, pyridoxine, nicotinic acid, folic acid and choline in chicks.
Topics: Animals; Chickens; Choline; Cold Temperature; Environment; Folic Acid; Hot Temperature; Niacin; Nicotinic Acids; Nutritional Requirements; Nutritional Sciences; Pyridoxine; Temperature; Thiamine; Vitamin B Complex; Vitamins | 1947 |
Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment.
Topics: Analysis of Variance; Animals; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Culture Media; DNA Methylation; Female; Folic Acid; Genomic Imprinting; Methionine; Mice; Oocytes; Ovarian Follicle; Radioimmunoassay; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; RNA, Untranslated; snRNP Core Proteins; Vitamin B 12; Vitamin B 6 | 2010 |
The importance of being choline.
Topics: Brain; Choline; Choline Deficiency; Folic Acid; Humans; Lipotropic Agents; Liver; Methionine; Nootropic Agents; Nutrition Policy; Nutritional Requirements | 2010 |
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12 | 2011 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
Hyperchromic anemia produced by choline or acetyl choline and the induced remission of both by folic acid or liver injection; the probable mechanism of action of liver and folic acid in treatment of anemia.
Topics: Acetylcholine; Anemia; Choline; Folic Acid; Liver; Liver Extracts; Vitamin B Complex; Vitamins | 1946 |
Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age.
Topics: Acetylcholine; Aging; Animals; Brain; Choline; Choline Deficiency; Diet; Dopamine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Lung; Male; Myocardium; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2010 |
Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes.
Topics: Animals; Bacteria; Betaine; Choline; Colitis; Dietary Supplements; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Maternal Nutritional Physiological Phenomena; Metagenome; Mice; Mice, Inbred C57BL; Pedigree; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2011 |
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.
Topics: Animals; Biomarkers; Choline; Choline Deficiency; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Gene Expression; Glycine Hydroxymethyltransferase; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Tube Defects; Purines; Severity of Illness Index; Thymidine Monophosphate; Thymidylate Synthase; Vitamin B Complex | 2011 |
Folate and choline metabolism gene variants and development of uterine cervical carcinoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Alleles; Betaine-Homocysteine S-Methyltransferase; Choline; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Models, Biological; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Uterine Cervical Neoplasms | 2011 |
Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.
Topics: Adult; Choline; Endometriosis; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Humans; Infertility, Female; Methylenetetrahydrofolate Reductase (NADPH2); Multifactor Dimensionality Reduction; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Severity of Illness Index; Young Adult | 2011 |
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver.
Topics: Animals; Betaine; Choline; Dietary Fats; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; Fatty Liver; Folic Acid; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Vitamin B 12 | 2011 |
Policy statement on folic acid and neural tube defects.
Topics: Choline; Dietary Supplements; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Vitamin B Complex | 2011 |
Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice.
Topics: Animals; Choline; Female; Folic Acid; Genotype; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors | 2011 |
Brain biochemical correlates of the plasma homocysteine level: a proton magnetic resonance spectroscopy study in the elderly subjects.
Topics: Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Cobamides; Creatine; Female; Folic Acid; Frontal Lobe; Hippocampus; Homocysteine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sex Characteristics | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice.
Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Energy Intake; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Mice; Mice, Knockout; Neural Tube Defects; Risk Factors | 2012 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Folate-responsive birth defects: of mice and women.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Mutation; Neural Tube Defects; Thymidine Monophosphate; Vitamin B Complex | 2012 |
Folate and choline metabolism gene variants in relation to ovarian cancer risk in the Polish population.
Topics: Cadherins; Case-Control Studies; Choline; Databases, Genetic; DNA Methylation; Epistasis, Genetic; Female; Folic Acid; Gene Frequency; Genes, Neoplasm; Genetic Predisposition to Disease; Humans; Incidence; Metabolic Networks and Pathways; Middle Aged; Ovarian Neoplasms; Poland; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors | 2012 |
Altered placental methyl donor transport in the dexamethasone programmed rat.
Topics: Animals; Biological Transport; Choline; Dexamethasone; DNA Methylation; Embryonic Development; Epistasis, Genetic; Female; Folic Acid; Methane; Methionine; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2012 |
Vitamin A, folate, and choline as a possible preventive intervention to fetal alcohol syndrome.
Topics: Animals; Avitaminosis; Choline; Epigenesis, Genetic; Female; Fetal Alcohol Spectrum Disorders; Folic Acid; Humans; Mice; Pregnancy; Rats; Risk Factors; Socioeconomic Factors; Vitamin A | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy | 2012 |
Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population.
Topics: Adult; Betaine; Choline; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Infant, Newborn; Long Interspersed Nucleotide Elements; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Vitamin B 12 | 2012 |
Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro.
Topics: Adult; Apoptosis; Cell Death; Cell Nucleus; Cells, Cultured; Choline; Choline Deficiency; DNA Damage; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Necrosis | 2012 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
Maternal intake of methyl-donor nutrients and child cognition at 3 years of age.
Topics: Adult; Betaine; Child Development; Child, Preschool; Choline; Cognition; Cohort Studies; Diet; DNA Methylation; Female; Folic Acid; Food; Humans; Massachusetts; Maternal Age; Maternal Nutritional Physiological Phenomena; Methionine; Multivariate Analysis; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2012 |
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.
Topics: Alkaline Phosphatase; Animal Feed; Animals; Apoptosis; beta Catenin; Cadherins; Caspase 3; Cell Differentiation; Choline; Choline Deficiency; Enterocytes; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Intestine, Small; Muramidase; Paneth Cells; Rats; Rats, Wistar; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism.
Topics: Animal Feed; Animals; Choline; Choline Deficiency; Cytochrome P-450 Enzyme System; Diet; DNA Damage; Fatty Liver; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genetic Variation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Protein Array Analysis; Transcriptome | 2012 |
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers.
Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
The interactive effect of dietary water-soluble vitamin levels on the depression of gonadal development in growing male rats kept under disturbed daily rhythm.
Topics: Animals; Biotin; Body Weight; Choline; Chronobiology Disorders; Diet; Dietary Supplements; Folic Acid; Male; Niacin; Organ Size; Pantothenic Acid; Rats; Rats, Inbred F344; Riboflavin; Testis; Thiamine; Vitamin B 6; Vitamin B Complex; Vitamins | 2012 |
Choline and betaine intake is inversely associated with breast cancer risk: a two-stage case-control study in China.
Topics: Betaine; Breast Neoplasms; Case-Control Studies; China; Choline; Diet; Eating; Female; Folic Acid; Humans; Logistic Models; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires | 2013 |
Introduction: the diverse and essential biological functions of vitamins.
Topics: Ascorbic Acid; Biotin; Choline; Folic Acid; Humans; Niacin; Nutritional Requirements; Pantothenic Acid; Riboflavin; Thiamine; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin E; Vitamin K; Vitamins | 2012 |
The beneficial effect of folate-enriched egg on the folate and homocysteine levels in rats fed a folate- and choline-deficient diet.
Topics: Animal Feed; Animals; Choline; Diet; Egg Yolk; Folic Acid; Food, Fortified; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex | 2013 |
Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.
Topics: Aged; Alcohol Drinking; Bayes Theorem; Betaine; Case-Control Studies; Choline; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Vitamin B Complex | 2013 |
Choline intake during pregnancy and child cognition at age 7 years.
Topics: Adult; Betaine; Child; Child Development; Choline; Cognition; Dietary Supplements; Female; Folic Acid; Humans; Intelligence; Male; Massachusetts; Memory; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Smoking; Socioeconomic Factors; Vitamin B 12 | 2013 |
Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury.
Topics: Animals; Carbon; Choline; Choline Deficiency; Cystathionine beta-Synthase; Disease Models, Animal; Down-Regulation; Fatty Liver; Folic Acid; Folic Acid Deficiency; Humans; Liver; Male; Methionine Adenosyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred Strains; Non-alcoholic Fatty Liver Disease; Species Specificity | 2013 |
One-carbon metabolism factors and leukocyte telomere length.
Topics: Aged; Biomarkers; Carbon; Choline; Cross-Sectional Studies; Diet; DNA; DNA Methylation; Ethanol; Folic Acid; Genotype; Humans; Leukocytes; Metabolic Networks and Pathways; Methionine; Middle Aged; Multivariate Analysis; Nutritional Status; Polymorphism, Single Nucleotide; Surveys and Questionnaires; Telomere; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.
Topics: Animals; Antibodies, Antinuclear; Betaine; CD40 Ligand; Choline; Coenzymes; Diet; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Genetic Predisposition to Disease; Lupus Erythematosus, Systemic; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Zinc | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
Topics: Aminohydrolases; Animals; Cell Proliferation; Cells, Cultured; Choline; Congenital Abnormalities; Embryo Loss; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Knock-In Techniques; Genetic Variation; Humans; Leucovorin; Leukocyte Count; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Models, Animal; Multienzyme Complexes; Multifunctional Enzymes; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Purines | 2013 |
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Male; Methionine; Middle Aged; Pregnancy; Prospective Studies; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Effects of methyl donor diets on incisional pain in mice.
Topics: Animals; Choline; Dietary Supplements; Female; Folic Acid; Hindlimb; Hyperalgesia; Male; Methionine; Mice; Mice, Inbred C57BL; Pain; Vitamin B 12; Weaning | 2013 |
Pubertal supplementation of lipotropes in female rats reduces mammary cancer risk by suppressing histone deacetylase 1.
Topics: Animals; Breast Neoplasms; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Female; Folic Acid; Histone Deacetylase 1; Methionine; Methylnitrosourea; Micronutrients; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Vitamin B 12 | 2014 |
Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort.
Topics: Aged; Biomarkers; Choline; Cohort Studies; DNA Methylation; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Leukocytes; Middle Aged; Postmenopause | 2014 |
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.
Topics: Adult; Aged; Betaine; Case-Control Studies; Choline; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet.
Topics: Adipose Tissue; Animals; Betaine; Body Composition; Choline; Diet; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Folic Acid; Gene Expression; Lactation; Liver; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; Receptors, Leptin; RNA, Messenger; Vitamin B 12 | 2014 |
Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.
Topics: Adult; Betaine; Case-Control Studies; Choline; Dietary Supplements; Female; Folic Acid; Genome, Human; Genotype; Humans; Logistic Models; Neural Tube Defects; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Selection, Genetic; Young Adult | 2014 |
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12 | 2014 |
Growth and nutrition in children with food allergy requiring amino acid-based nutritional formulas.
Topics: Adolescent; Adolescent Development; Amino Acids; Carbohydrates; Child; Child Development; Child, Preschool; Choline; Fats; Female; Folic Acid; Food Hypersensitivity; Food, Formulated; Humans; Infant; Male; Micronutrients; Proteins; Trace Elements; Vitamins | 2014 |
In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.
Topics: Animals; Choline; Dimethylglycine Dehydrogenase; Folic Acid; Folic Acid Deficiency; Formaldehyde; Formates; Glycine; Histidine; Liver; Male; Methionine; Mitochondria; Mitochondria, Liver; Oxygen; Rats; Rats, Sprague-Dawley; Sarcosine Dehydrogenase; Serine; Tetrahydrofolates | 2015 |
The effects of methyl-donor deficiency on the pattern of gene expression in mice.
Topics: Animals; Choline; Deficiency Diseases; Diet; Female; Folic Acid; Gene Expression Regulation; Kidney; Liver; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Inbred CBA; Spleen; Tissue Array Analysis | 2015 |
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.
Topics: Adolescent; Adult; Belgium; Betaine; Choline; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Nutrition Assessment; Reproducibility of Results; Surveys and Questionnaires; Young Adult | 2015 |
Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus.
Topics: Age Factors; Animals; Choline; Choline Deficiency; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Memory; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Nutritional Requirements; Promoter Regions, Genetic; Receptors, AMPA; Receptors, Glutamate | 2015 |
Folate and nutrients involved in the 1-carbon cycle in the pretreatment of patients for colorectal cancer.
Topics: Aged; Brazil; Carbon Cycle; Choline; Colorectal Neoplasms; Dietary Carbohydrates; Dietary Proteins; Dietary Supplements; Energy Intake; Female; Folic Acid; Humans; Male; Middle Aged; Riboflavin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Choline; Diet; Dietary Supplements; Female; Fetal Development; Fetal Weight; Fetus; Folic Acid; Gene Expression; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor II; Liver; Maternal Nutritional Physiological Phenomena; Methionine; Micronutrients; Muscle, Skeletal; Pregnancy; Signal Transduction; Swine; Vitamin B 12; Vitamin B 6 | 2016 |
A method comparison of a food frequency questionnaire to measure folate, choline, betaine, vitamin C and carotenoids with 24-h dietary recalls in women of reproductive age.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Betaine; Body Mass Index; Carotenoids; Choline; Diet Surveys; Educational Status; Energy Intake; Ethnicity; Female; Folic Acid; Follow-Up Studies; Humans; Mental Recall; Micronutrients; Nutrition Assessment; Reproducibility of Results; Reproduction; Surveys and Questionnaires; United Kingdom; White People; Young Adult | 2016 |
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Suppression of Mammary Carcinogenesis Through Early Exposure to Dietary Lipotropes Occurs Primarily In Utero.
Topics: Animals; Animals, Newborn; Choline; Chromatin Assembly and Disassembly; Diet; Female; Folic Acid; Histone Deacetylases; Lactation; Mammary Neoplasms, Animal; Maternal-Fetal Exchange; Methionine; Methylnitrosourea; Pregnancy; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2015 |
Serum betaine but not choline is inversely associated with breast cancer risk: a case-control study in China.
Topics: Adult; Aged; Betaine; Breast Neoplasms; Case-Control Studies; China; Choline; Diet; Exercise; Female; Folic Acid; Humans; Logistic Models; Middle Aged; Nutritional Status; Risk Factors; Socioeconomic Factors | 2017 |
Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice.
Topics: Animals; Choline; CpG Islands; Cytosine; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Folic Acid; Histones; Liver; Mice; Mice, Inbred A; Mice, Inbred Strains; Non-alcoholic Fatty Liver Disease | 2016 |
Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk.
Topics: Aged; Amino Acids; Betaine; Biomarkers; Biomarkers, Tumor; Case-Control Studies; Choline; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Protective Factors; Sarcosine; Sweden | 2016 |
Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Homocysteine; Hypoxia; Male; Maze Learning; Memory; Memory Disorders; Mice; Phosphorylation; tau Proteins; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report | 2016 |
Dietary Methyl Donor Depletion Suppresses Intestinal Adenoma Development.
Topics: Adenoma; Animals; Choline; Diet; Folic Acid; Intestinal Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Random Allocation; Vitamin B 12 | 2016 |
A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children's Oncology Group.
Topics: Child, Preschool; Choline; Dietary Supplements; Female; Folic Acid; Gene-Environment Interaction; Genetic Variation; Genotype; Humans; Infant; Male; Neuroblastoma; Odds Ratio; Polymorphism, Single Nucleotide; Pregnancy; Registries; United States | 2016 |
Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet.
Topics: Animals; Betaine; Choline; Cysteine; Diet; Feeding Behavior; Folic Acid; Methionine; Methylation; Protein Biosynthesis; Swine | 2016 |
Dietary Methyl Donors Contribute to Whole-Body Protein Turnover and Protein Synthesis in Skeletal Muscle and the Jejunum in Neonatal Piglets.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Dose-Response Relationship, Drug; Female; Folic Acid; Jejunum; Male; Methionine; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Faecal and Serum Metabolomics in Paediatric Inflammatory Bowel Disease.
Topics: Adolescent; Amino Acids; Carnosine; Case-Control Studies; Child; Choline; Colitis, Ulcerative; Crohn Disease; Feces; Female; Folic Acid; Humans; Leukocyte L1 Antigen Complex; Male; Metabolic Networks and Pathways; Metabolomics; Prospective Studies; Ribose; Sex Factors; Signal Transduction; Sphingolipids | 2017 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Choline metabolic pathway gene polymorphisms and risk for Down syndrome: An association study in a population with folate-homocysteine metabolic impairment.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Child; Choline; Choline Dehydrogenase; Down Syndrome; Female; Folic Acid; Genetic Association Studies; Genotype; Homocysteine; Humans; Metabolic Networks and Pathways; Mothers; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Risk Factors | 2017 |
Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
Topics: Aminohydrolases; Animals; Choline; Dietary Supplements; Embryo, Mammalian; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Logistic Models; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Multienzyme Complexes; Placenta; Polymorphism, Single Nucleotide; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation.
Topics: Adult; Betaine; Choline; Cohort Studies; Diet; Dietary Supplements; DNA Methylation; Epigenomics; Feeding Behavior; Female; Fetal Blood; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Nutrition Surveys; Pregnancy; Surveys and Questionnaires | 2017 |
Micronutrient Intake Is Inadequate for a Sample of Pregnant African-American Women.
Topics: Adolescent; Adult; Black or African American; Body Mass Index; Calcium, Dietary; Choline; Energy Intake; Female; Folic Acid; Humans; Iron, Dietary; Micronutrients; New England; Nutrition Assessment; Poverty; Pregnancy; Pregnant Women; Prospective Studies; Vitamin D; Young Adult | 2017 |
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants.
Topics: Betaine; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; High-Throughput Nucleotide Sequencing; Humans; Infant; Insulin-Like Growth Factor II; Leptin; Maternal Nutritional Physiological Phenomena; Nutrition Surveys; Pregnancy; Retinoid X Receptor alpha; Sequence Analysis, DNA | 2017 |
The effect of paternal methyl-group donor intake on offspring DNA methylation and birth weight.
Topics: Adult; Belgium; Betaine; Birth Weight; Choline; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Male; Methionine; Middle Aged; Obesity | 2017 |
[Effect of peripheral bloodgenomic DNA methylation on the relationship between methyl donor status and risk of breast cancer].
Topics: Betaine; Breast Neoplasms; Case-Control Studies; Choline; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Risk | 2017 |
Maternal Exposure to Nitrogen Dioxide, Intake of Methyl Nutrients, and Congenital Heart Defects in Offspring.
Topics: Adult; Air Pollutants; Air Pollution; Case-Control Studies; Choline; Diet Records; Eating; Female; Folic Acid; Food Analysis; Heart Defects, Congenital; Humans; Infant, Newborn; Maternal Exposure; Methionine; Nitrogen Dioxide; Odds Ratio; Pregnancy; Prenatal Nutritional Physiological Phenomena; Risk Factors; United States; Vitamin B 12; Vitamin B 6 | 2017 |
Methyl-Donor and Cofactor Nutrient Intakes in the First 2-3 Years and Global DNA Methylation at Age 4: A Prospective Cohort Study.
Topics: Child, Preschool; Choline; Diet; Diet Records; Dietary Supplements; DNA Methylation; Female; Folic Acid; Humans; Linear Models; Longitudinal Studies; Male; Mental Recall; Methionine; Mouth Mucosa; Nutrition Assessment; Prospective Studies; Riboflavin; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2018 |
Oxidative stress and dietary micronutrient deficiencies contribute to overexpression of epigenetically regulated genes by lupus T cells.
Topics: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes; Choline; Diet; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Methionine; Micronutrients; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Riboflavin; T-Lymphocytes; Vitamin B 12; Vitamin B 6; Young Adult; Zinc | 2018 |
Fetal one-carbon nutrient concentrations may be affected by gestational diabetes.
Topics: Adult; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Fetal Blood; Fetal Development; Fetus; Folic Acid; Humans; Infant, Newborn; Nutrients; Nutritional Status; Pregnancy; Prenatal Care; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates.
Topics: Animals; Animals, Newborn; Betaine; Blood; Choline; Female; Folic Acid; Male; Methionine; Methylation; Swine; Vitamin U | 2018 |
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltransferase; Diet; Female; Folic Acid; Genotype; Homozygote; Humans; Infant, Newborn; Methylamines; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Young Adult | 2018 |
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission | 2019 |
Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Topics: Aged; Carnitine; Case-Control Studies; China; Choline; Female; Folic Acid; Gastrointestinal Microbiome; Humans; Hypertension; Male; Methylamines; Middle Aged; Odds Ratio; Stroke | 2018 |
Sex differences in hepatic one-carbon metabolism.
Topics: Betaine; Carbon; Choline; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Models, Biological; Sex Characteristics | 2018 |
Paternal methyl donor deficient diets during development affect male offspring behavior and memory-related gene expression in mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Fear; Folic Acid; Gene Expression; Male; Methionine; Mice; Mice, Inbred C57BL; Receptors, Neuropeptide Y | 2019 |
Dietary intake and food sources of one-carbon metabolism nutrients in preschool aged children.
Topics: Australia; Child Nutritional Physiological Phenomena; Child, Preschool; Choline; Diet; Female; Folic Acid; Humans; Male; Methionine; Nutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2019 |
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine | 2019 |
Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study.
Topics: Adult; Aged; Australia; Betaine; Carbon; Case-Control Studies; Choline; Diet; Female; Folic Acid; Helicobacter Infections; Humans; Male; Middle Aged; Nutrients; Odds Ratio; Riboflavin; Risk Factors; Stomach Neoplasms; Vitamin B Complex | 2019 |
One-Carbon Cofactor Intake and Risk of Neural Tube Defects Among Women Who Meet Folic Acid Recommendations: A Multicenter Case-Control Study.
Topics: Adult; Betaine; Carbon; Case-Control Studies; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Methionine; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Socioeconomic Factors; United States; Vitamin B 12; Vitamin B 6 | 2019 |
Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant Polish women.
Topics: Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Choline; Female; Folic Acid; Genotype; Glutathione; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Genetic; Pregnancy; Pregnancy Trimester, Third; Young Adult | 2020 |
A high methyl donor diet affects physiology and behavior in Peromyscus polionotus.
Topics: Absorptiometry, Photon; Animals; Anxiety; Behavior, Animal; Betaine; Choline; Diet; DNA Methylation; Female; Folic Acid; Gonadotropin-Releasing Hormone; Male; Peromyscus; Social Behavior; Vitamin B 12 | 2019 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Choline, not folate, can attenuate the teratogenic effects ofdibutyl phthalate (DBP) during early chick embryo development.
Topics: Animals; Apoptosis; Body Fluids; Chick Embryo; Chickens; Choline; Dibutyl Phthalate; Embryonic Development; Environmental Pollutants; Female; Folic Acid; Humans; Maternal Exposure; Neural Tube Defects; Oxidative Stress; Teratogenesis | 2019 |
Using Differential Threshold Effects of Individual and Combined Periconceptional Methyl Donor Status on Maternal Genomic LINE-1 and Imprinted H19 DNA Methylation to Predict Birth Weight Variance in the Taiwan Pregnancy-Newborn Epigenetics (TPNE) Cohort St
Topics: Adult; Betaine; Birth Weight; Choline; Cohort Studies; Differential Threshold; DNA; DNA Methylation; Epigenomics; Female; Folic Acid; Genomics; Humans; Infant, Newborn; Long Interspersed Nucleotide Elements; Pregnancy; RNA, Long Noncoding; Taiwan | 2020 |
Low protein diet and methyl-donor supplements modify testicular physiology in mice.
Topics: Animals; Betaine; Choline; Diet, Protein-Restricted; Dietary Supplements; Fatty Acids; Folic Acid; Male; Methionine; Mice; Testis; Vitamin B 12 | 2020 |
High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis.
Topics: Animals; Cholesterol; Choline; Diet; DNA Methylation; Folic Acid; Food, Fortified; Homeostasis; Humans; Lipid Metabolism; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Protein 2; Receptors, Lipoprotein | 2021 |
Alterations in One-Carbon Metabolism in Celiac Disease.
Topics: Adolescent; Carbon; Celiac Disease; Child; Child, Preschool; Choline; Cross-Sectional Studies; Diet, Gluten-Free; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Methionine | 2020 |
Choline and Folic Acid in Diets Consumed during Pregnancy Interact to Program Food Intake and Metabolic Regulation of Male Wistar Rat Offspring.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Appetite Regulation; Body Weight; Brain; Choline; Eating; Female; Folic Acid; Gene Expression; Hypothalamus; Insulin; Intra-Abdominal Fat; Leptin; Male; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Models, Animal; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Weaning | 2021 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
Antiseizure medications and fetal nutrients: Effects on choline transporters in a human placental cell line.
Topics: Adult; Anticonvulsants; Antigens, CD; Cell Line; Choline; Female; Fetus; Folic Acid; Gene Expression Regulation; Humans; Levetiracetam; Membrane Glycoproteins; Membrane Transport Proteins; Metabolic Networks and Pathways; Nutrients; Organic Cation Transport Proteins; Placenta; Pregnancy; Valproic Acid | 2021 |
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors | 2021 |
Excess Vitamins or Imbalance of Folic Acid and Choline in the Gestational Diet Alter the Gut Microbiota and Obesogenic Effects in Wistar Rat Offspring.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Choline; Diet; Female; Folic Acid; Gastrointestinal Microbiome; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Vitamins | 2021 |
Validation of a food-frequency questionnaire to assess methyl-group donor intake in preschoolers.
Topics: Adult; Betaine; Child; Choline; Diet; Diet Records; Diet Surveys; Energy Intake; Folic Acid; Humans; Reproducibility of Results; Surveys and Questionnaires | 2022 |
Optimal Dietary Intake Composition of Choline and Betaine Is Associated with Minimized Visceral Obesity-Related Hepatic Steatosis in a Case-Control Study.
Topics: Adiposity; Aged; Betaine; Biomarkers; Body Composition; Case-Control Studies; Choline; Diet Records; Eating; Fatty Liver; Female; Folic Acid; Humans; Male; Middle Aged; Obesity; Obesity, Abdominal; Odds Ratio; Taiwan; Ultrasonography | 2022 |
Micronutrients of the one-carbon metabolism cycle are altered in mothers and neonates by gestational diabetes and are associated with weight, height and head circumference at birth.
Topics: Betaine; Birth Weight; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Glycine; Humans; Infant, Newborn; Micronutrients; Mothers; Pregnancy; Tandem Mass Spectrometry; Vitamin B 12 | 2022 |
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status.
Topics: Case-Control Studies; Choline; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA Mismatch Repair; Folic Acid; Humans; Methionine; Microsatellite Instability; Niacin; Nutrients; Polymorphism, Genetic; Risk Factors | 2022 |
Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women.
Topics: Betaine; Biomarkers; Choline; Fatty Liver; Female; Folic Acid; Glutathione; Homocysteine; Humans; Postmenopause | 2022 |
Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice.
Topics: Animals; Choline; Collaborative Cross Mice; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Female; Folic Acid; Lipidomics; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Sucrose | 2022 |
Characterization of Choline Nutriture among Adults and Children with Phenylketonuria.
Topics: Adult; Child; Choline; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Phenylalanine; Phenylketonurias; Pregnancy; Vitamin B 12; Vitamins | 2022 |
One-carbon metabolism-related nutrients intake is associated with lower risk of preeclampsia in pregnant women: a matched case-control study.
Topics: Case-Control Studies; Choline; Eating; Female; Folic Acid; Humans; Methionine; Nutrients; Pre-Eclampsia; Pregnancy; Pregnant Women; Pyridoxine; Racemethionine; Vitamin B 12; Vitamin B 6; Vitamins | 2022 |
[Folate, Choline, and Vitamin B12 Supplementation for Pre-Conceptional and Pregnant Women].
Topics: Animals; Choline; Dietary Supplements; Female; Folic Acid; Humans; Lactation; Neural Tube Defects; Pregnancy; Pregnant Women; Vitamin B 12 | 2022 |
Prenatal trimester-specific intake of micronutrients: global DNA methylation and hydroxymethylation at birth and persistence in childhood.
Topics: Child, Preschool; Choline; DNA Methylation; Female; Folic Acid; Humans; Infant, Newborn; Micronutrients; Pregnancy; Vitamins | 2023 |
One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme transcript abundance in a dose-dependent manner.
Topics: Animals; Carbon; Cattle; Choline; Dietary Supplements; Estrous Cycle; Female; Folic Acid; Liver; Methionine; Racemethionine; Rumen; S-Adenosylmethionine | 2023 |
Children Aged 5-6 Years in Vancouver, Canada Meet Dietary Recommendations for Folate and Vitamin B12 but not Choline.
Topics: Biomarkers; Canada; Child; Choline; Cross-Sectional Studies; Diet; Folic Acid; Humans; United States; Vitamin B 12; Vitamin B Complex | 2023 |
Associations between maternal folate status and choline intake during pregnancy and neurodevelopment at 3-4 years of age in the Alberta Pregnancy Outcomes and Nutrition (APrON) study.
Topics: Alberta; Animals; Child; Child, Preschool; Choline; Dietary Supplements; Female; Folic Acid; Humans; Pregnancy; Pregnancy Outcome | 2023 |
Maternal Dietary Deficiencies in Folic Acid and Choline Result in Larger Damage Volume, Reduced Neuro-Degeneration and -Inflammation and Changes in Choline Metabolites after Ischemic Stroke in Middle-Aged Offspring.
Topics: Animals; Choline; Dietary Supplements; Female; Folic Acid; Inflammation; Ischemic Stroke; Lactation; Male; Mice; Pregnancy; Stroke | 2023 |
[A complex of B vitamins, choline and inosine in the treatment of chronic pain].
Topics: Choline; Chronic Pain; Folic Acid; Humans; Inosine; Vitamin B Complex | 2023 |
[Assessment of the role of nutritional and genetic determinants in the formation of the risk of diseases associated with folate cycle disorders in the population of the Omsk region].
Topics: Adult; Case-Control Studies; Choline; Female; Folic Acid; Genotype; Humans; Male; Methionine; Polymorphism, Genetic | 2023 |
Association between nutrient intake related to the one-carbon metabolism and colorectal cancer risk: a case-control study in the Basque Country.
Topics: Betaine; Carbon; Case-Control Studies; Choline; Colorectal Neoplasms; Diet; Eating; Folic Acid; Humans; Logistic Models; Risk Factors; Spain | 2023 |
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
Topics: Alzheimer Disease; Animals; Betaine; Carbon; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Humans; Mice; Mice, Transgenic; Phosphorylation; Protein Phosphatase 2; tau Proteins; Tauopathies | 2023 |
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation.
Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements | 2023 |
Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recom
Topics: Betaine; Carbon; Case-Control Studies; Choline; Female; Folic Acid; Humans; Methionine; Micronutrients; Neural Tube Defects; Racemethionine; Trace Elements; Vitamin B 6 | 2023 |
Maternal dietary intake among alcohol-exposed pregnancies is linked to early infant physical outcomes in South Africa.
Topics: Calcium; Choline; Diet; Eating; Ethanol; Fatty Acids; Female; Fetal Alcohol Spectrum Disorders; Folic Acid; Humans; Infant; Magnesium; Pregnancy; Prenatal Exposure Delayed Effects; South Africa; Vitamin A; Vitamin B 6; Vitamins; Zinc | 2023 |
Impact of maternal dietary folic acid or choline dietary deficiencies on vascular function in young and middle-aged female mouse offspring after ischemic stroke.
Topics: Animals; Carbon; Choline; Diet; Female; Folic Acid; Humans; Ischemic Stroke; Maternal Nutritional Physiological Phenomena; Mice; Pregnancy; Prenatal Exposure Delayed Effects | 2023 |