cholic acid and simvastatin

cholic acid has been researched along with simvastatin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Aldini, R; Bazzoli, F; Cipolla, A; Festi, D; Mazzella, G; Parini, P; Roda, A; Roda, E; Salzetta, A; Tonelli, D1
Benhizia, F; Griglio, S; Lagrange, D; Malewiak, MI1
Gao, Y; Huang, L; Jiang, L; Liu, G; Mei, L; Shi, X; Tao, W; Wang, X; Wang, Z; Wu, Y; Zeng, X1
Abd El-Alim, SH; Darwish, AB; Salama, A1
Gao, H; Huang, X; Liu, J; Zhang, Q; Zhang, W1

Trials

1 trial(s) available for cholic acid and simvastatin

ArticleYear
Effect of simvastatin, ursodeoxycholic acid and simvastatin plus ursodeoxycholic acid on biliary lipid secretion and cholic acid kinetics in nonfamilial hypercholesterolemia.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Bile; Cholesterol; Cholic Acid; Cholic Acids; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kinetics; Lipid Metabolism; Liver; Lovastatin; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid

1992

Other Studies

6 other study(ies) available for cholic acid and simvastatin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver.
    Biochimica et biophysica acta, 1994, Mar-03, Volume: 1211, Issue:2

    Topics: Animals; Body Weight; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cholic Acid; Cholic Acids; Diet; Female; Hydroxymethylglutaryl CoA Reductases; Lipase; Lipid Metabolism; Lipids; Liver; Lovastatin; Rats; Rats, Zucker; RNA, Messenger; Simvastatin

1994
Novel Simvastatin-Loaded Nanoparticles Based on Cholic Acid-Core Star-Shaped PLGA for Breast Cancer Treatment.
    Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cholic Acid; Diffusion; Female; Lactic Acid; Mice; Mice, Inbred BALB C; Nanocapsules; Neoplasms, Experimental; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Simvastatin; Tissue Distribution; Treatment Outcome

2015
Provesicular elastic carriers of Simvastatin for enhanced wound healing activity: An in-vitro/in-vivo study.
    International journal of pharmaceutics, 2020, Jul-30, Volume: 585

    Topics: Animals; Chemistry, Pharmaceutical; Cholesterol; Collagen Type I; Drug Carriers; Drug Liberation; Drug Stability; Hexoses; Male; Particle Size; Polysorbates; Rats; Rats, Wistar; Simvastatin; Sodium Cholate; Vascular Endothelial Growth Factor A; Wound Healing

2020
Regulating the Size of Simvastatin-loaded Discoidal Reconstituted Highdensity Lipoprotein: Preparation, Characterization, and Investigation of Cellular Cholesterol Efflux.
    Current drug delivery, 2023, Volume: 20, Issue:5

    Topics: Cholesterol; Lipoproteins, HDL; Macrophages; Simvastatin; Sodium Cholate

2023