Compounds > cholic acid

cholic acid and obeticholic acid

cholic acid has been researched along with obeticholic acid in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auwerx, J; Costantino, G; Gioiello, A; Giorgi, G; Macchiarulo, A; Pellicciari, R; Sadeghpour, BM; Sato, H; Schoonjans, K1
Auwerx, J; Gioiello, A; Macchiarulo, A; Natalini, B; Pastorini, E; Pellicciari, R; Pruzanski, M; Roda, A; Rosatelli, E; Sardella, R; Schoonjans, K; Thomas, C1
Auwerx, J; De Franco, F; Ferrari, C; Giacchè, N; Gioiello, A; Macchiarulo, A; Nuti, R; Pellicciari, R; Pols, TW; Pruzanski, M; Schoonjans, K; Thomas, C1
Carotti, A; Colliva, C; De Franco, F; Filipponi, P; Franco, P; Gadaleta, RM; Gioiello, A; Macchiarulo, A; Moschetta, A; Mostarda, S; Passeri, D; Pellicciari, R; Roda, A1
Gu, XZ; He, XL; Qiu, WW; Wang, LT; Xiao, JX1
Feng, W; Hao, Z; Liu, Y; Ren, L; Song, Q; Zhang, L1
Faber, KN; Groen, AK; Heegsma, J; Paulusma, CC; Saeed, A; van Mil, SWC; Wang, B; Yang, J; Zhou, L1

Other Studies

7 other study(ies) available for cholic acid and obeticholic acid

ArticleYear
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.
    Journal of medicinal chemistry, 2007, Sep-06, Volume: 50, Issue:18

    Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; DNA-Binding Proteins; Humans; Ligands; Methylation; Models, Molecular; Molecular Structure; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Ursodeoxycholic Acid

2007
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.
    Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24

    Topics: Animals; Chlorocebus aethiops; CHO Cells; Cholic Acids; COS Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Humans; Obesity; Rats; Receptors, G-Protein-Coupled; Stereoisomerism

2009
Probing the Binding Site of Bile Acids in TGR5.
    ACS medicinal chemistry letters, 2013, Dec-12, Volume: 4, Issue:12

    Topics:

2013
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.
    Journal of medicinal chemistry, 2016, Oct-13, Volume: 59, Issue:19

    Topics:

2016
A facile synthesis of ursodeoxycholic acid and obeticholic acid from cholic acid.
    Steroids, 2018, Volume: 140

    Topics: Chemistry Techniques, Synthetic; Chenodeoxycholic Acid; Cholic Acid; Cost-Benefit Analysis; Ursodeoxycholic Acid

2018
Probiotic Lactobacillus rhamnosus GG prevents progesterone metabolite epiallaopregnanolone sulfate-induced hepatic bile acid accumulation and liver injury.
    Biochemical and biophysical research communications, 2019, 11-26, Volume: 520, Issue:1

    Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid

2019
Farnesoid X receptor and bile acids regulate vitamin A storage.
    Scientific reports, 2019, 12-20, Volume: 9, Issue:1

    Topics: Acyltransferases; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Hepatocytes; Liver; Mice; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; Vitamin A

2019