cholic acid has been researched along with methotrexate in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
| Griffin, D; Said, HM | 1 |
| Balinska, M; Fox, MP; Galivan, J; Nimec, Z | 1 |
| Henderson, GB; Hughes, TR; Saxena, M | 2 |
| Henderson, GB; Saxena, M | 1 |
| Chen, G; Fawcett, JP; Mikov, M; Tucker, IG | 1 |
| Cha, JH; Kim, HS; Kim, JK; Qureshi, OS; Zeb, A | 1 |
10 other study(ies) available for cholic acid and methotrexate
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |
The enterohepatic circulation of methotrexate in vivo: inhibition by bile salt.
Topics: Animals; Bile; Cholic Acid; Cholic Acids; Enterohepatic Circulation; Liver; Male; Methotrexate; Rats; Rats, Inbred Strains | 1987 |
Factors controlling the concentrations of methotrexate in cultured hepatic cells.
Topics: Animals; Anions; Biotransformation; Cell Survival; Cells, Cultured; Cholic Acid; Cholic Acids; Liver; Male; Methotrexate; Rats; Tetrahydrofolate Dehydrogenase | 1982 |
Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells.
Topics: Biological Transport; Cells, Cultured; Cholic Acid; Cholic Acids; Dinitrochlorobenzene; Ethacrynic Acid; Hematopoietic Stem Cells; Humans; Indomethacin; Lymphocytes; Methotrexate; Prostaglandins A | 1995 |
ATP-dependent efflux of 2,4-dinitrophenyl-S-glutathione. Properties of two distinct transport systems in inside-out vesicles from L1210 cells and a variant subline with altered efflux of methotrexate and cholate.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cell Membrane; Cholic Acid; Cholic Acids; Clone Cells; Glutathione; Kinetics; Leukemia L1210; Methotrexate; Mice; Tritium; Tumor Cells, Cultured | 1995 |
Functional implications from the effects of 1-chloro-2,4-dinitrobenzene and ethacrynic acid on efflux routes for methotrexate and cholate in L1210 cells.
Topics: Adenosine Triphosphate; Animals; Anions; Biological Transport; Cholic Acid; Cholic Acids; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Leukemia L1210; Methotrexate; Mice; Tumor Cells, Cultured | 1994 |
Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Animals; Area Under Curve; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Intestinal Absorption; Male; Methotrexate; Rats; Rats, Wistar; Sodium Cholate | 2009 |
Improved skin permeation of methotrexate via nanosized ultradeformable liposomes.
Topics: Administration, Cutaneous; Animals; Drug Carriers; Drug Delivery Systems; Liposomes; Male; Methotrexate; Microscopy, Confocal; Nanostructures; Particle Size; Phosphatidylcholines; Polysorbates; Rats, Sprague-Dawley; Skin; Skin Absorption; Sodium Cholate | 2016 |