cholic acid and gw 4064

cholic acid has been researched along with gw 4064 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, Y; Hayashi, H; Misawa, T; Sugiyama, Y1
Hashimoto, Y; Hayashi, H; Makishima, M; Misawa, T; Sugiyama, Y1
Bundman, D; Chua, SS; Han, Y; Heyman, RA; Karin, M; Kim, CS; Lee, YK; Moore, DD; Thevananther, S; Wang, L; Wei, P1
Björkhem, I; Eggertsen, G; Einarsson, C; Gåfvels, M; Murphy, C; Parini, P; Wang, J1
Edwards, PA; Kast-Woelbern, HR; Lusis, AJ; Shih, DM; Wong, J; Xia, YR1
Baptissart, M; Baron, S; Caira, F; de Haze, A; Martinot, E; Rouaisnel, B; Schoonjans, K; Sédes, L; Vega, A; Volle, DH1

Other Studies

6 other study(ies) available for cholic acid and gw 4064

ArticleYear
Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2.
    Bioorganic & medicinal chemistry, 2012, May-01, Volume: 20, Issue:9

    Topics: Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cell Line; Cholestasis, Intrahepatic; Dogs; Drug Evaluation, Preclinical; Endoplasmic Reticulum; Gene Expression; Isoxazoles; Mutation; Phenylbutyrates; Structure-Activity Relationship

2012
E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: structural development study and separation from farnesoid X receptor-agonistic activity.
    Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

    Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cell Line; Dogs; Dose-Response Relationship, Drug; Humans; Isoxazoles; Mutation; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2012
Redundant pathways for negative feedback regulation of bile acid production.
    Developmental cell, 2002, Volume: 2, Issue:6

    Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; DNA-Binding Proteins; Feedback; Homeostasis; Isoxazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Nicotinic Acids; Nuclear Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; RNA, Messenger; Stem Cells; Tetrahydronaphthalenes; Transcription Factors

2002
Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice.
    Journal of lipid research, 2006, Volume: 47, Issue:2

    Topics: Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Cholic Acid; DNA-Binding Proteins; Feces; Female; Gene Expression; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Isoxazoles; Lipids; Lipoproteins; Liver; Liver X Receptors; Male; Mice; Mice, Knockout; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Steroid 12-alpha-Hydroxylase; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factors

2006
A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
    Journal of lipid research, 2006, Volume: 47, Issue:2

    Topics: Administration, Oral; Animals; Anthracenes; Aryldialkylphosphatase; Bile Acids and Salts; Cell Line, Tumor; Chenodeoxycholic Acid; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Cholic Acid; Dietary Fats; DNA-Binding Proteins; Enzyme Inhibitors; Female; Fibroblast Growth Factors; Gene Expression; Humans; Isoxazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phospholipid Transfer Proteins; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Sterol Regulatory Element Binding Protein 1; Transcription Factors

2006
Bile acid-FXRα pathways regulate male sexual maturation in mice.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Animals; Bile Acids and Salts; Cell Line; Cholic Acid; Fertility; Isoxazoles; Leydig Cells; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Receptors, Cytoplasmic and Nuclear; RNA Interference; Sexual Maturation; Signal Transduction; Testis; Testosterone

2016