Page last updated: 2024-09-03

cholestyramine resin and pravastatin

cholestyramine resin has been researched along with pravastatin in 56 studies

Compound Research Comparison

Studies
(cholestyramine resin)
Trials
(cholestyramine resin)
Recent Studies (post-2010)
(cholestyramine resin)
Studies
(pravastatin)
Trials
(pravastatin)
Recent Studies (post-2010) (pravastatin)
2,6693421903,5751,036816

Protein Interaction Comparison

ProteinTaxonomycholestyramine resin (IC50)pravastatin (IC50)
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.1452
Insulin receptor Rattus norvegicus (Norway rat)0.0056
Prostaglandin G/H synthase 2Homo sapiens (human)0.0056
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0254
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.6

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.36)18.7374
1990's45 (80.36)18.2507
2000's8 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itakura, H1
Clifton, P; Janus, ED; Nestel, PJ; Parfitt, A; Simons, J; Simons, LA1
Arai, H; Hara, S; Ishii, K; Kita, T; Kume, N; Nagano, Y; Otani, H; Ueda, Y; Yokode, M1
Alessandri, C; Peverini, F1
Fukami, M; Fukushige, J; Itakura, H; Ito, T; Kuroda, M; Matsumoto, A; Nara, F; Shiomi, M; Tsujita, Y; Watanabe, Y1
Jacob, BG; Möhrle, W; Richter, WO; Schwandt, P1
Aviram, M; Brook, GJ; Hoffman, R1
Betteridge, DJ; Bhatnager, D; Bing, RF; Durrington, PN; Evans, GR; Flax, H; Jay, RH; Lewis-Barned, N; Mann, J; Matthews, DR1
Mimura, K; Yukawa, S1
Dammann, HG; Ditschuneit, H; Ditschuneit, HH; Dreyer, M1
Angelin, B1
Berrocal, M; Chang, S; Drexler, A; Gordon, B; Kavanagh, M; Robertson, C; Yannuzzi, L1
Angelin, B; Berglund, L; Dallner, G; Elmberger, PG; Eriksson, M; Kalén, A; Lund, E; Reihnér, E1
Betteridge, DJ; Jay, RH; Katz, M; McGarrigle, HH; Reckless, JP; Stirling, C; Sturley, RH1
Angelin, B; Berglund, L; Bondjers, G; Eriksson, M; Fager, G; Olofsson, SO; Wiklund, O1
Batta, A; Ness, G; Nguyen, LB; Packin, V; Salen, G; Shefer, S; Shore, V; Tanaka, RD; Thomas, P1
Bard, JM; Douste-Blazy, P; Fruchart, JC; Parra, HJ1
Maher, VM; Thompson, GR1
Brescia, D; DeVault, AR; Ivashkiv, E; Pan, HY; Swites, BJ; Whigan, D; Willard, DA1
Arai, M; Fukami, M; Fukushige, J; Ito, T; Kuroda, M; Shiomi, M; Tamura, A; Tsujita, Y; Watanabe, Y1
Angelin, B; Berglund, L; Bondjers, G; Eriksson, M; Fager, G; Lindén, T; Olofsson, SO; Sjöberg, A; Wiklund, O1
Kurota, M; Maeda, H; Matsuda, T; Miyaho, S; Morikawa, K; Nakai, T; Oida, K; Takahashi, S; Takai, H; Tamai, T1
Bimmermann, A; Schleicher, J; Schwartzkopff, W1
Betteridge, DJ; Jay, RH; Rampling, MW1
Freudenberger, JS; Lee, LY; Mosley, ST; Schafer, BL; Tanaka, RD1
Arai, H; Ishii, K; Kawai, C; Kita, T; Kume, N; Nagano, Y; Otani, H; Ueda, Y; Yokode, M1
Ishii, K; Kawai, C; Kita, T; Kume, N; Mikami, A; Nagano, Y; Yokode, M1
Reynolds, GA1
Ebisuno, S; Isohashi, F; Nakanishi, Y; Sakamoto, Y1
Jacob, BG; Richter, WO; Schwandt, P1
Bowler, A; Elsegood, CL; Mamo, JC; Redgrave, TG1
Gibson, CM; Pasternak, RC; Rosner, B; Sacks, FM; Stone, PH1
Angelin, B; Berglund, L; Bondjers, G; Eggertsen, G; Eriksson, M; Lindén, T; Olofsson, SO; Wiklund, O1
Dobs, AS; Goldberg, A; Guccione, M; Hoover, DR; Prasad, M1
Wendelhag, I; Wiklund, O; Wikstrand, J1
Kamata, K; Kasuya, Y; Suenaga, H; Sugiura, M1
Dotti, MT; Federico, A; Lindenthal, B; Lütjohann, D; Simatupang, A; von Bergmann, K1
Bambauer, R; Müller, UA; Schiel, R1
Hidaka, H; Kashiwagi, A; Kawabata, T; Kikkawa, R; Kojima, H; Konaka, K; Nakamura, T; Shigeta, Y1
Corrigan, F1
Bönner, G1
Ito, MK; Shabetai, R1
Ikeda, K; Michihara, A; Nara, Y; Sawamura, M; Yamori, Y1
Eriksson, M; Hådell, K; Holme, I; Kjellström, T; Walldius, G1
Higashikata, T; Inazu, A; Kajinami, K; Koizumi, J; Mabuchi, H; Yagi, K1
Agrawal, R; Arntz, HR; Fischer, F; Linderer, T; Schnitzer, L; Schultheiss, HP; Stern, R; Wunderlich, W1
Fukui, T; Iwahori, A; Iwama, M; Nakamoto, M; Takahashi, N1
El-Sohemy, A1
Agrawal, R; Arntz, HR; Fischer, F; Schnitzer, L; Schultheiss, HP; Stern, R; Wunderlich, W1
Kersting, F; Selenka, A; Walch, S1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M1
Mishra, TK; Routray, S1
Asaka, M; Imamura, M; Kanamori, H; Kawamura, T; Masauzi, N; Miura, T; Obara, S; Tanaka, J; Tsutsumi, Y; Yamato, H1
Plans-Rubió, P1

Reviews

2 review(s) available for cholestyramine resin and pravastatin

ArticleYear
[Clinical evaluation of a selective inhibitor of cholesterol synthesis: pravastatin].
    Minerva medica, 1992, Volume: 83, Issue:11

    Topics: Adult; Animals; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Pravastatin; Rats; Risk Factors; Simvastatin; Time Factors

1992
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
    Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome

2003

Trials

19 trial(s) available for cholestyramine resin and pravastatin

ArticleYear
Treatment of primary hypercholesterolaemia with pravastatin: efficacy and safety over three years.
    The Medical journal of Australia, 1992, Nov-02, Volume: 157, Issue:9

    Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Safety; Treatment Outcome; Triglycerides

1992
Treatment of familial hypercholesterolaemia. United Kingdom lipid clinics study of pravastatin and cholestyramine.
    BMJ (Clinical research ed.), 1992, May-23, Volume: 304, Issue:6838

    Topics: Adolescent; Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pravastatin; Treatment Outcome; Triglycerides

1992
[Pravastatin, cholestyramine and gemfibrozil in long-term therapy of primary hypercholesterolemia. An open randomized comparative study].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Mar-15, Volume: 86, Issue:3

    Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholestyramine Resin; Female; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides

1991
Effects of pravastatin and cholestyramine on gonadal and adrenal steroid production in familial hypercholesterolaemia.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:4

    Topics: Adrenal Glands; Cholestyramine Resin; Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Gonads; Humans; Hydrocortisone; Hyperlipoproteinemia Type II; Male; Pravastatin; Sex Hormone-Binding Globulin; Steroids

1991
HMG CoA reductase inhibitors as lipid-lowering agents: five years experience with lovastatin and an appraisal of simvastatin and pravastatin.
    The Quarterly journal of medicine, 1990, Volume: 74, Issue:274

    Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Phenotype; Pravastatin; Simvastatin; Time Factors

1990
Pharmacokinetics and pharmacodynamics of pravastatin alone and with cholestyramine in hypercholesterolemia.
    Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Phospholipids; Pravastatin; Randomized Controlled Trials as Topic; Triglycerides

1990
Treatment of familial hypercholesterolaemia: a controlled trial of the effects of pravastatin or cholestyramine therapy on lipoprotein and apolipoprotein levels.
    Journal of internal medicine, 1990, Volume: 228, Issue:3

    Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Apolipoproteins; Aspartate Aminotransferases; Cholesterol, LDL; Cholestyramine Resin; Double-Blind Method; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Naphthalenes; Pravastatin; Randomized Controlled Trials as Topic; Triglycerides

1990
[Comparison of the effectiveness of the HMG-CoA-reductase inhibitors pravastatin versus colestyramine in hypercholesteremia].
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:12

    Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides

1990
Abnormalities of blood rheology in familial hypercholesterolaemia: effects of treatment.
    Atherosclerosis, 1990, Volume: 85, Issue:2-3

    Topics: Adult; Anticholesteremic Agents; Blood Viscosity; Cholestyramine Resin; Erythrocyte Aggregation; Erythrocyte Deformability; Female; Fibrinogen; Hematocrit; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Male; Middle Aged; Naphthalenes; Pravastatin; Rheology

1990
Effect on coronary atherosclerosis of decrease in plasma cholesterol concentrations in normocholesterolaemic patients. Harvard Atherosclerosis Reversibility Project (HARP) Group.
    Lancet (London, England), 1994, Oct-29, Volume: 344, Issue:8931

    Topics: Anticholesteremic Agents; Cardiac Catheterization; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Gemfibrozil; Humans; Lipids; Male; Middle Aged; Niacin; Pravastatin; Treatment Outcome

1994
Apolipoprotein E phenotypes in familial hypercholesterolaemia: importance for expression of disease and response to therapy.
    Journal of internal medicine, 1993, Volume: 233, Issue:2

    Topics: Apolipoproteins E; Cholestyramine Resin; Double-Blind Method; Humans; Hyperlipoproteinemia Type II; Lipids; Phenotype; Pravastatin; Treatment Outcome

1993
Comparative efficacy and safety of pravastatin and cholestyramine alone and combined in patients with hypercholesterolemia. Pravastatin Multicenter Study Group II.
    Archives of internal medicine, 1993, Jun-14, Volume: 153, Issue:11

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Creatine Kinase; Double-Blind Method; Drug Combinations; Female; Humans; Hypercholesterolemia; Liver; Male; Middle Aged; Placebos; Pravastatin; Safety; Triglycerides

1993
Changes in serum lipoprotein(a) in hyperlipidemic subjects undergoing long-term treatment with lipid-lowering drugs.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Double-Blind Method; Humans; Hyperlipidemias; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides

1995
Four years' treatment efficacy of patients with severe hyperlipidemia. Lipid lowering drugs versus LDL-apheresis.
    The International journal of artificial organs, 1995, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Anticholesteremic Agents; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Longitudinal Studies; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Quality of Life

1995
Pravastatin alone and in combination with low-dose cholestyramine in patients with primary hypercholesterolemia and coronary artery disease.
    The American journal of cardiology, 1997, Sep-15, Volume: 80, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Coronary Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Triglycerides

1997
Compliance with and efficacy of treatment with pravastatin and cholestyramine: a randomized study on lipid-lowering in primary care.
    Journal of internal medicine, 1998, Volume: 243, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Patient Compliance; Pravastatin; Primary Health Care; Sex Factors; Sweden; Treatment Outcome

1998
[Short- and long-term effects of intensified versus conventional antilipidemic therapy in patients with coronary heart disease. Results from the Lipid-Coronary Artery Disease (L-CAD) Study].
    Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:8

    Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Coronary Disease; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Niacin; Pravastatin; Prospective Studies; Treatment Outcome

1999
Beneficial effects of pravastatin (+/-colestyramine/niacin) initiated immediately after a coronary event (the randomized Lipid-Coronary Artery Disease [L-CAD] Study).
    The American journal of cardiology, 2000, Dec-15, Volume: 86, Issue:12

    Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Chemoprevention; Chi-Square Distribution; Cholesterol, LDL; Cholestyramine Resin; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Drug Combinations; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Niacin; Odds Ratio; Peripheral Vascular Diseases; Pravastatin; Regression Analysis; Statistics, Nonparametric; Stroke; Survival Rate; Treatment Outcome

2000
Effects of cholestyramine on vitamin E levels in patients treated with statins.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:12 Pt 2

    Topics: Adult; Aged; Anticholesteremic Agents; Antioxidants; Cholesterol, LDL; Cholestyramine Resin; Drug Interactions; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Vitamin E

2000

Other Studies

35 other study(ies) available for cholestyramine resin and pravastatin

ArticleYear
[Treatment of hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Blood Component Removal; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Coronary Disease; Dietary Fiber; Energy Intake; Female; Humans; Hyperlipidemias; Male; Niceritrol; Pravastatin; Probucol

1992
The role of oxidized lipoproteins in the pathogenesis of atherosclerosis.
    Clinical and experimental pharmacology & physiology. Supplement, 1992, Volume: 20

    Topics: Animals; Apolipoproteins B; Cholesterol Esters; Cholestyramine Resin; Coronary Artery Disease; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mice; Oxidation-Reduction; Pravastatin; Probucol; Rabbits; Receptors, LDL; RNA, Messenger

1992
Effects of pravastatin sodium alone and in combination with cholestyramine on hepatic, intestinal and adrenal low density lipoprotein receptors in homozygous Watanabe heritable hyperlipidemic rabbits.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:1

    Topics: Adrenal Glands; Animals; Cholesterol, LDL; Cholestyramine Resin; Drug Synergism; Hyperlipidemias; Intestinal Mucosa; Intestines; Liver; Male; Pravastatin; Rabbits; Receptors, LDL; RNA, Messenger

1992
Short- and long-term effects of lovastatin and pravastatin alone and in combination with cholestyramine on serum lipids, lipoproteins and apolipoproteins in primary hypercholesterolaemia.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides

1992
Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies.
    Atherosclerosis, 1992, Volume: 93, Issue:1-2

    Topics: Adult; Animals; Bezafibrate; Cells, Cultured; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Esterification; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Male; Malondialdehyde; Mice; Middle Aged; Pravastatin; Vitamin E

1992
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidney Failure, Chronic; Niceritrol; Pantetheine; Pravastatin; Probucol; Vitamin E

1991
Regulation of hepatic cholesterol metabolism in man.
    Annals of medicine, 1991, Volume: 23, Issue:2

    Topics: Cholelithiasis; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Naphthalenes; Pravastatin; Receptors, LDL

1991
The effects of lipid lowering on diabetic retinopathy.
    American journal of ophthalmology, 1991, Oct-15, Volume: 112, Issue:4

    Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Dietary Fats; Female; Humans; Hyperlipidemias; Male; Middle Aged; Pravastatin; Triglycerides; Visual Acuity

1991
Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia.
    Journal of lipid research, 1991, Volume: 32, Issue:6

    Topics: Adult; Aged; Cholesterol; Cholestyramine Resin; Dolichols; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Male; Mevalonic Acid; Middle Aged; Pravastatin; Ubiquinone

1991
Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia.
    Lancet (London, England), 1990, Jun-09, Volume: 335, Issue:8702

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins A; Cholestyramine Resin; Coronary Disease; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Naphthalenes; Pravastatin; Receptors, LDL

1990
Purification of cholesterol 7 alpha-hydroxylase from human and rat liver and production of inhibiting polyclonal antibodies.
    The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8

    Topics: Animals; Antibodies; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Cholestyramine Resin; Chromatography; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Heptanoic Acids; Humans; Immunoblotting; Isoenzymes; Male; Microsomes, Liver; Molecular Weight; Naphthalenes; Pravastatin; Rats; Rats, Inbred Strains; Starvation; Steroid Hydroxylases

1990
Effect of pravastatin, an HMG CoA reductase inhibitor, and cholestyramine, a bile acid sequestrant, on lipoprotein particles defined by their apolipoprotein composition.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:3

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Apolipoproteins C; Apolipoproteins E; Bile Acids and Salts; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Evaluation; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Naphthalenes; Pravastatin; Random Allocation; Triglycerides

1990
Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low. Effect of pravastatin sodium in combination with cholestyramine.
    Atherosclerosis, 1990, Volume: 83, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta; Arteriosclerosis; Cholesterol; Cholestyramine Resin; Coronary Disease; Heptanoic Acids; Naphthalenes; Phospholipids; Pravastatin; Rabbits; Triglycerides; Xanthomatosis

1990
[A case of familial hypercholesterolemia associated with nephrotic syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Aug-10, Volume: 79, Issue:8

    Topics: Cholestyramine Resin; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Middle Aged; Naphthalenes; Nephrotic Syndrome; Pravastatin; Prednisolone; Probucol

1990
Purification and regulation of mevalonate kinase from rat liver.
    The Journal of biological chemistry, 1990, Feb-05, Volume: 265, Issue:4

    Topics: Amino Acids; Animals; Anticholesteremic Agents; Cholestyramine Resin; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Female; Fluorides; Heptanoic Acids; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Kinetics; Liver; Lovastatin; Molecular Weight; Naphthalenes; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pravastatin; Rats; Rats, Inbred Strains; Reference Values

1990
Lipoproteins and atherosclerosis.
    Japanese circulation journal, 1990, Volume: 54, Issue:9

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholesterol Esters; Cholestyramine Resin; Disease Models, Animal; Foam Cells; Heptanoic Acids; Hyperlipidemia, Familial Combined; Lipoproteins, LDL; Liver; Macrophages; Mice; Naphthalenes; Pravastatin; Probucol; Rabbits; Receptors, Cell Surface; Receptors, Lipoprotein

1990
Induction of mRNA for low-density lipoprotein receptors in heterozygous Watanabe heritable hyperlipidemic rabbits treated with CS-514 (Pravastatin) and cholestyramine.
    Circulation, 1989, Volume: 79, Issue:5

    Topics: Animals; Anticholesteremic Agents; Cholestyramine Resin; Heptanoic Acids; Heterozygote; Hyperlipoproteinemia Type II; Liver; Male; Naphthalenes; Pravastatin; Rabbits; Receptors, LDL; RNA, Messenger

1989
Rational therapy of familial hypercholesterolemia.
    Circulation, 1989, Volume: 79, Issue:5

    Topics: Animals; Anticholesteremic Agents; Cholestyramine Resin; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Naphthalenes; Pravastatin; Rabbits; Receptors, LDL

1989
Acetyl-CoA hydrolase: relation between activity and cholesterol metabolism in rat.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Acetyl-CoA Hydrolase; Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofibric Acid; Cytosol; Diabetes Mellitus, Experimental; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Naphthalenes; Pravastatin; Rats; Thiolester Hydrolases

1988
Long-term treatment (2 years) with the HMG CoA reductase inhibitors lovastatin or pravastatin in combination with cholestyramine in patients with severe primary hypercholesterolemia.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Triglycerides

1993
Clearance of chylomicron-like lipid emulsions is increased in normal rabbits but not in heterozygous Watanabe heritable hyperlipidaemic rabbits following treatment with cholestyramine or pravastatin.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:9

    Topics: Analysis of Variance; Animals; Bile Acids and Salts; Cholestyramine Resin; Chylomicrons; Fat Emulsions, Intravenous; Heterozygote; Hydroxymethylglutaryl CoA Reductases; Hyperlipoproteinemia Type II; Metabolic Clearance Rate; Pravastatin; Rabbits

1994
Intima-media thickness after cholesterol lowering in familial hypercholesterolemia. A three-year ultrasound study of common carotid and femoral arteries.
    Atherosclerosis, 1995, Volume: 117, Issue:2

    Topics: Anticholesteremic Agents; Carotid Artery, Common; Cholesterol; Cholestyramine Resin; Female; Femoral Artery; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Tunica Intima; Tunica Media; Ultrasonography

1995
[Effect of cholestyramine on angiopathies in cholesterol-fed mice and diabetic mice].
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6

    Topics: Animals; Anticholesteremic Agents; Cholesterol, Dietary; Cholestyramine Resin; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hypercholesterolemia; Male; Mice; Mice, Inbred ICR; Pravastatin; Vascular Diseases; Vasodilation

1995
Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis.
    Journal of lipid research, 1996, Volume: 37, Issue:10

    Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Middle Aged; Pravastatin; Reproducibility of Results; Simvastatin; Xanthomatosis, Cerebrotendinous

1996
Effects of an HMG-CoA reductase inhibitor, pravastatin, and bile sequestering resin, cholestyramine, on plasma plant sterol levels in hypercholesterolemic subjects.
    Journal of atherosclerosis and thrombosis, 1995, Volume: 2, Issue:1

    Topics: Acyl Coenzyme A; Adult; Anticholesteremic Agents; Cholestyramine Resin; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Pravastatin

1995
Lipid-lowering drugs and mortality.
    The British journal of psychiatry : the journal of mental science, 1997, Volume: 170

    Topics: Cholestyramine Resin; Coronary Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Pravastatin; Treatment Outcome

1997
[Care Study. Secondary prevention after myocardial infarct in moderately elevated total cholesterol].
    Fortschritte der Medizin, 1997, Jun-20, Volume: 115, Issue:17

    Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Combined Modality Therapy; Diet, Fat-Restricted; Humans; Hyperlipidemias; Myocardial Infarction; Pravastatin; Risk Factors; Survival Rate

1997
Purification and characterization of two mevalonate pyrophosphate decarboxylases from rat liver: a novel molecular species of 37 kDa.
    Journal of biochemistry, 1997, Volume: 122, Issue:3

    Topics: Animals; Anticholesteremic Agents; Carboxy-Lyases; Cholesterol; Cholestyramine Resin; Enzyme Induction; Glycosylation; Hydrogen-Ion Concentration; Immunoblotting; Immunohistochemistry; Isoelectric Point; Isoenzymes; Kinetics; Liver; Male; Molecular Weight; Oligosaccharides; Pravastatin; Rats; Rats, Inbred WKY

1997
Low-density lipoprotein receptor genotype-dependent response to cholesterol lowering by combined pravastatin and cholestyramine in familial hypercholesterolemia.
    The American journal of cardiology, 1998, Jul-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Anion Exchange Resins; Anticholesteremic Agents; Bile; Cholestyramine Resin; Drug Therapy, Combination; Female; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Male; Middle Aged; Pravastatin; Receptors, LDL; Treatment Outcome

1998
cDNA-derived amino acid sequence of acetoacetyl-CoA synthetase from rat liver.
    FEBS letters, 2000, Jan-28, Volume: 466, Issue:2-3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cholestyramine Resin; Coenzyme A Ligases; Diet; DNA, Complementary; Female; Liver; Molecular Sequence Data; Pravastatin; Rats; Rats, Sprague-Dawley; Sequence Homology, Amino Acid

2000
Statin drugs and the risk of fracture.
    JAMA, 2000, Oct-18, Volume: 284, Issue:15

    Topics: Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cholestyramine Resin; Fractures, Bone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pravastatin; Risk; Transforming Growth Factor beta

2000
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention.
    Prescrire international, 1999, Volume: 8, Issue:42

    Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome

1999
Current perspectives on statins.
    Journal of the Indian Medical Association, 2003, Volume: 101, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Coronary Artery Disease; Female; Humans; India; Lovastatin; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Simvastatin

2003
Rhabdomyolysis caused by distigmine bromide.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:11

    Topics: Aged; Anticholesteremic Agents; Cholestyramine Resin; Drug Interactions; Female; Humans; Muscle, Skeletal; Pravastatin; Pyridinium Compounds; Rhabdomyolysis; Urinary Retention

2003
Cost-effectiveness analysis of cholesterol-lowering therapies in Spain.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2006, Volume: 6, Issue:3

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Meta-Analysis as Topic; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Spain

2006