cholestyramine resin has been researched along with methotrexate in 11 studies
| Studies (cholestyramine resin) | Trials (cholestyramine resin) | Recent Studies (post-2010) (cholestyramine resin) | Studies (methotrexate) | Trials (methotrexate) | Recent Studies (post-2010) (methotrexate) |
|---|---|---|---|---|---|
| 2,669 | 342 | 190 | 41,593 | 5,666 | 11,969 |
| Protein | Taxonomy | cholestyramine resin (IC50) | methotrexate (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 1.8 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 0.211 | |
| Toll-like receptor 4 | Homo sapiens (human) | 1.04 | |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 0.08 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0522 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0331 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0348 | |
| Dihydrofolate reductase | Gallus gallus (chicken) | 0.0545 | |
| Dihydrofolate reductase | Enterococcus faecium | 0.0014 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.0138 | |
| Thymidylate synthase | Homo sapiens (human) | 0.343 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0147 | |
| Thymidylate synthase | Escherichia coli K-12 | 0.0181 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1529 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.084 | |
| Folate receptor beta | Homo sapiens (human) | 0.1585 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0011 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.0012 | |
| Folate receptor alpha | Homo sapiens (human) | 0.2263 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0717 | |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | 0.0014 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.01 | |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | 0.01 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Reduced folate transporter | Homo sapiens (human) | 0.012 | |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | 0.0174 | |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | 3.2 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.0547 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.11 | |
| Dihydrofolate reductase | Bacillus anthracis | 0.0136 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0047 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.1207 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheurlen, M; Weber, P; Wiedmann, KH | 1 |
| Kaplan, MM | 1 |
| Daly, JM; McAnena, OJ; Ridge, JA | 1 |
| Erttmann, R; Gkanatsas, A | 1 |
| Erttmann, R; Landbeck, G | 1 |
| Cain, GD; Rahman, F | 1 |
| Strum, WB | 1 |
| Horiuchi, R; Shinozaki, T; Takagishi, K; Tomidokoro, R; Watanabe, H; Yamamoto, K | 1 |
| Szalay, F | 1 |
| Carrera, A; Jiménez-Torres, NV; Merino-Sanjuán, M; Monte, E | 1 |
| Koulaouzidis, A | 1 |
3 review(s) available for cholestyramine resin and methotrexate
| Article | Year |
|---|---|
Medical approaches to primary sclerosing cholangitis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipruritics; Azathioprine; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Humans; Mercaptopurine; Methotrexate; Penicillamine; Ursodeoxycholic Acid; Vitamins | 1991 |
Current concepts in therapy: drug-induced malabsorption--a review.
Topics: Aminosalicylic Acids; Calcium Carbonate; Cholestyramine Resin; Clofibrate; Colchicine; Contraceptives, Oral; Diuretics; Ethanol; Humans; Intestinal Absorption; Malabsorption Syndromes; Mannitol; Methotrexate; Phenytoin | 1973 |
[Treatment of primary biliary cirrhosis].
Topics: Antioxidants; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Colchicine; Enzyme Inhibitors; Humans; Liver; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Ursodeoxycholic Acid | 2003 |
8 other study(ies) available for cholestyramine resin and methotrexate
| Article | Year |
|---|---|
[Methotrexate in the therapy of primary biliary cirrhosis].
Topics: Adult; Alkaline Phosphatase; Bilirubin; Cholesterol; Cholestyramine Resin; Drug Evaluation; Female; Humans; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Pilot Projects; Time Factors | 1991 |
Alteration of methotrexate metabolism in rats by administration of an elemental liquid diet. II. Reduced toxicity and improved survival using cholestyramine.
Topics: Animals; Bile; Cholestyramine Resin; Diet; Drug Interactions; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Metabolic Clearance Rate; Methotrexate; Rats | 1987 |
[Clinical significance of non-renal elimination mechanisms of methotrexate (MTX)].
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bile; Child; Child, Preschool; Cholestyramine Resin; Chromatography, High Pressure Liquid; Enterohepatic Circulation; Female; Femoral Neoplasms; Humans; Kinetics; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Neoplasms; Osteosarcoma | 1985 |
Effect of oral cholestyramine on the elimination of high-dose methotrexate.
Topics: Administration, Oral; Adolescent; Bile; Charcoal; Child; Cholestyramine Resin; Female; Humans; Methotrexate | 1985 |
Characteristics of the transport of pteroylglutamate and amethopterin in rat jejunum.
Topics: Animals; Cholestyramine Resin; Diffusion; Drug Interactions; Ethanol; Folic Acid; Hydrogen-Ion Concentration; Intestinal Absorption; Jejunum; Male; Methotrexate; Rats; Serum Albumin, Bovine; Sodium; Sulfasalazine | 1981 |
Successful rescue by oral cholestyramine of a patient with methotrexate nephrotoxicity: nonrenal excretion of serum methotrexate.
Topics: Anion Exchange Resins; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Cholestyramine Resin; Humans; Kidney; Liver; Male; Methotrexate; Osteosarcoma; Tibia; Time Factors; Treatment Outcome | 2000 |
Adsorption of methotrexate and calcium leucovorin onto cholestyramine in vitro.
Topics: Adsorption; Anion Exchange Resins; Antimetabolites, Antineoplastic; Cholestyramine Resin; Hydrogen-Ion Concentration; Leucovorin; Methotrexate | 2004 |
Microscopic colitis and endoscopy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Azathioprine; Cholestyramine Resin; Colitis, Collagenous; Colitis, Lymphocytic; Colonoscopy; Cyclosporine; Gastric Mucosa; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Methotrexate; Proton Pump Inhibitors | 2009 |